Knowledge (XXG)

Ping Zhang (biologist)

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PKA kinase fusion protein. Zhang's lab applies integrated structural biology (single-particle cryo-electron microscopy and X-ray crystallography) and biochemical approaches to achieve our objective of studying these kinase complexes in their functional states. This strategy is used to reveal the
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signaling complexes that are linked to human cancers and other diseases, with a long-term goal of developing new therapeutic strategies. She is a NIH Stadtman Investigator in the Structural Biophysics Laboratory at the
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signaling complexes that are linked to human cancers and other diseases, with a long-term goal of developing new therapeutic strategies. Current research topics include the
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mechanistic details and factors critical for driving the functional activities of these kinases and how these activities may be altered in pathological states.
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Investigator in August 2016. She researches the structural and mechanistic basis of multi-component
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Ping was an assistant project scientist in the department of pharmacology at the
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researching the structural and mechanistic basis of multi-component
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system related to human diseases and learning other techniques in
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This article incorporates text from this source, which is in the
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This article incorporates text from this source, which is in the
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This article incorporates text from this source, which is in the
152:(cryo-EM).  She completed her postdoctoral training at 176:
that are suited for studying dynamic signaling complexes.
140:. Her Ph.D. project was resolving the structures of 188:. She joined the Structural Biophysics Laboratory at 82: 68: 57: 40: 21: 8: 382:University of California, San Diego faculty 29: 18: 272:Carter, Laura Stephenson (2018-12-18). 222: 397:21st-century American women scientists 7: 377:National Institutes of Health people 305: 303: 267: 265: 230: 228: 226: 186:University of California, San Diego 162:University of California, San Diego 73:University of California, San Diego 407:American women medical researchers 402:American people of Chinese descent 350:from websites or documents of the 14: 346: This article incorporates 341: 325: 288: 250: 315:NIH Intramural Research Program 278:NIH Intramural Research Program 154:Howard Hughes Medical Institute 1: 352:National Institutes of Health 274:"The Merry Band of Stadtmans" 150:cryogenic electron microscopy 16:American structural biologist 412:American cancer researchers 124:Zhang completed a Ph.D. in 428: 239:Center for Cancer Research 392:American women biologists 311:"Principal Investigators" 190:National Cancer Institute 114:National Cancer Institute 94: 77:National Cancer Institute 50: 28: 372:Purdue University alumni 192:(NCI) as a NIH Stadtman 348:public domain material 387:Structural biologists 146:X-ray crystallography 105:structural biologist 236:"Ping Zhang, Ph.D." 206:leucine-rich repeat 180:Career and research 166:signal transduction 142:poliovirus-receptor 170:structural biology 62:Structural biology 204:kinases, and the 160:’s laboratory at 130:Purdue University 98: 97: 52:Scientific career 45:Purdue University 419: 345: 344: 335: 329: 328: 324: 322: 321: 307: 298: 292: 291: 287: 285: 284: 269: 260: 254: 253: 249: 247: 246: 232: 144:complexes using 132:in the field of 126:Michael Rossmann 89:Michael Rossmann 84:Doctoral advisor 64:, cancer biology 33: 19: 427: 426: 422: 421: 420: 418: 417: 416: 357: 356: 355: 342: 339: 338: 326: 319: 317: 309: 308: 301: 289: 282: 280: 271: 270: 263: 251: 244: 242: 234: 233: 224: 219: 208:kinases and an 182: 164:, working on a 158:Susan S. Taylor 136:and structural 122: 103:is an American 75: 41:Alma mater 36: 24: 17: 12: 11: 5: 425: 423: 415: 414: 409: 404: 399: 394: 389: 384: 379: 374: 369: 359: 358: 340: 337: 336: 299: 261: 221: 220: 218: 215: 181: 178: 174:cell signaling 121: 118: 96: 95: 92: 91: 86: 80: 79: 70: 66: 65: 59: 55: 54: 48: 47: 42: 38: 37: 34: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 424: 413: 410: 408: 405: 403: 400: 398: 395: 393: 390: 388: 385: 383: 380: 378: 375: 373: 370: 368: 367:Living people 365: 364: 362: 353: 349: 333: 332:public domain 316: 312: 306: 304: 300: 296: 295:public domain 279: 275: 268: 266: 262: 258: 257:public domain 240: 237: 231: 229: 227: 223: 216: 214: 211: 207: 203: 199: 195: 191: 187: 179: 177: 175: 171: 167: 163: 159: 155: 151: 147: 143: 139: 135: 131: 127: 119: 117: 115: 110: 106: 102: 93: 90: 87: 85: 81: 78: 74: 71: 67: 63: 60: 56: 53: 49: 46: 43: 39: 35:Zhang in 2016 32: 27: 20: 318:. Retrieved 314: 281:. Retrieved 277: 243:. Retrieved 241:. 2016-08-24 238: 194:Tenure Track 183: 134:biochemistry 123: 100: 99: 69:Institutions 51: 361:Categories 320:2020-10-11 283:2020-10-11 245:2020-10-11 217:References 202:Raf family 128:’s lab at 101:Ping Zhang 23:Ping Zhang 210:oncogenic 120:Education 138:virology 156:and in 198:kinase 109:kinase 58:Fields 172:and 148:and 363:: 313:. 302:^ 276:. 264:^ 225:^ 116:. 354:. 334:. 323:. 297:. 286:. 259:. 248:.

Index


Purdue University
Structural biology
University of California, San Diego
National Cancer Institute
Doctoral advisor
Michael Rossmann
structural biologist
kinase
National Cancer Institute
Michael Rossmann
Purdue University
biochemistry
virology
poliovirus-receptor
X-ray crystallography
cryogenic electron microscopy
Howard Hughes Medical Institute
Susan S. Taylor
University of California, San Diego
signal transduction
structural biology
cell signaling
University of California, San Diego
National Cancer Institute
Tenure Track
kinase
Raf family
leucine-rich repeat
oncogenic

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