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displayed at the surface of the stigma epidermal cells that capture pollen and its small protein ligand located in the outer coating of pollen grains. His team conducted gene transfer experiments that demonstrated that these two genes are necessary and sufficient for determining specificity in the
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haplotype) explained how the stigma can discriminate between self- and non-self pollen grains in self-incompatible crucifers. This mechanism of self-recognition has now been shown to operate in all tested self-incompatible species from various crucifer genera, such as
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103:-centric focus which at the time had been the norm in research aimed at identifying the molecular components of self-incompatibility in various plant families, he reasoned that investigating the contribution of the
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as a starting point for identifying the molecular components of self-incompatibility has become common practice for molecular analysis of self-incompatibility across various plant families.
825:
Takayama, S; Shimosato, H; Shiba, H; Funato, M; Che, FS; Watanabe, M; Iwano, M; Isogai, A (2001). "Direct ligand-receptor complex interaction controls
Brassica self-incompatibility".
99:
As a doctoral student at
Cornell, Nasrallah made a major scientific contribution by devising a new approach to the molecular analysis of self-incompatibility. Instead of the
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self-incompatibility response. The subsequent finding that the interaction of the stigma receptor with its pollen ligand, and hence receptor activation, is
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Nasrallah, ME; Liu, P; Nasrallah, JB (2002). "Generation of self-incompatible
Arabidopsis thaliana by transfer of two S locus genes from A. lyrata".
67:
92:
Over the course of his career, Nasrallah's work has resulted in numerous scientific publications which have been cited over 10,000 times with an
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Kachroo, A; Schopfer, CR; Nasrallah, ME; Nasrallah, JB (2001). "Allele-specific receptor-ligand interactions in
Brassica self-incompatibility".
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205:'s highest scholastic honor, the Penrose Award, in 1960; an award in Horticulture from the Burpee Foundation in 1961; and an award from the
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125:. This approach led him to identify the first molecule encoded by an self-incompatibility–determining gene. This strategy of using the
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The stigma molecule identified by
Nasrallah was later used by his team at Cornell as a launching pad for a detailed analysis of the
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Nasrallah carried out postdoctoral research at
Cornell University from 1965-1967. He had a faculty position in Genetics at the
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to the self-incompatibility response would be a more successful approach for identifying molecules involved in SI. Working in
612:"Molecular cloning of a putative receptor protein kinase gene encoded at the self-incompatibility locus of Brassica oleracea"
26:
in flowering plants. He is professor emeritus in the Plant
Biology Section of the School of Integrative Plant Science in the
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47:
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Nasrallah, ME; Wallace, DH (1967). "Immunochemical detection of antigens in self-incompatibility genotypes of cabbage".
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haplotype-specific (i.e. they will only occur if the pollen ligand and the stigma receptor are derived from the same
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of 51. His research has also been featured in several perspective articles and paper alerts in high-impact journals.
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in 1970 in recognition of an outstanding research contribution related to a vegetable crop used for processing.
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Schopfer, CR; Nasrallah, ME; Nasrallah, JB (1999). "The male determinant of self-incompatibility in
Brassica".
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Schopfer, CR; Nasrallah, ME; Nasrallah, JB (1999). "The male determinant of self-incompatibility in
Brassica".
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MS thesis: Hybridization and inheritance studies in
Solanum melongena L., and selected Solanum species
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46:. He received a Bachelor of Science degree in Agriculture and a certification in Agronomy from the
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Physiological and immunogenetic studies on self-incompatibility in Brassica oleracea var. capitata
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Charlesworth, D (2000). "Plant Genetics: Unlocking the secrets of self-incompatibility".
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and at the surface of which "self" pollen grains are inhibited in self-incompatible
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Lewis, D (1952). "Serological reactions of pollen incompatibility substances".
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Self-incompatibility in Flowering Plants: Evolution, Diversity, and Mechanisms
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Much of Nasrallah's research has focused on the molecular genetic analysis of
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New York State College of Agriculture and Life Sciences at Cornell University
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417:"Self-incompatibility in Brassica: The elusive pollen S gene is identified!"
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Proceedings of the Royal Society of London. Series B - Biological Sciences
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Stein, JC; Howlett, B; Boyes, DC; Nasrallah, ME; Nasrallah, JB (1991).
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plants. This analysis led to the breakthrough demonstration that the
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in 1962, and a doctorate degree in Plant Breeding and Genetics from
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from 1967 to 1985, and subsequently moved to Cornell University.
85:) family. Self-incompatibility prevents flowering plants from
140:") control recognition of "self" pollen in self-incompatible
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locus, whose large number of variants (classically known as "
874:. No. Summer 2009. American University of Beirut. 2009.
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locus is a complex locus and that its "alleles" are in fact
589:(eBook ed.). Berlin, Heidelberg: Springer-Verlag.
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is a plant scientist, specialising in the genetics of
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in 1960, a Master's degree in Horticulture from the
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Proceedings of the National Academy of Sciences USA
89:or reproducing with genetically-related plants.
464:Schneiz, K (2002). "Plant Biology Paper alert".
277:(Ph. D. thesis). Ithaca, NY: Cornell University
8:
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635:
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415:Franklin-Tong, VE; Franklin, FCH (2000).
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207:American Institute of Biological Sciences
160:determinants of self-incompatibility: a
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117:, which is the structure that caps the
68:State University of New York/Cortland
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933:American University of Beirut alumni
252:. University of Vermont Howe Library
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466:Current Opinion in Plant Biology
227:"Mikhail Nasrallah | CALS"
1:
718:10.1126/science.286.5445.1697
683:10.1126/science.286.5445.1697
478:10.1016/S1369-5266(02)00308-4
394:10.1016/s0960-9822(00)00347-x
203:American University of Beirut
48:American University of Beirut
938:University of Vermont alumni
271:Nasrallah, Mikhail (1965).
246:Nasrallah, Mikhail (1962).
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948:Cornell University faculty
585:Franklin-Tong, VE (2008).
16:Plant molecular geneticist
943:Cornell University alumni
296:Charlesworth, D (2010).
886:"The Burpee Foundation"
869:"Maingate/Then and Now"
804:10.1126/science.1062509
761:10.1126/science.1072205
637:10.1073/pnas.88.19.8816
201:Nasrallah received the
513:10.1098/rspb.1952.0049
348:"Mikhail E. Nasrallah"
298:"Self-Incompatibility"
38:Nasrallah was born in
20:Mikhail Elia Nasrallah
890:The Burpee Foundation
52:University of Vermont
433:10.1105/tpc.12.3.305
113:, he focused on the
75:self-incompatibility
24:self-incompatibility
839:2001Natur.413..534T
796:2001Sci...293.1824K
790:(5536): 1824–1826.
753:2002Sci...297..247N
712:(5445): 1697–1700.
677:(5445): 1697–1700.
628:1991PNAS...88.8816S
556:1967Natur.213..700N
505:1952RSPSB.140..127L
386:2000CBio...10.R184C
62:Career and Research
352:scholar.google.com
56:Cornell University
833:(6855): 534–538.
747:(5579): 247–249.
622:(19): 8816–8820.
550:(5077): 700–701.
197:Awards and Honors
77:in plants of the
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421:Plant Cell
232:2024-07-26
213:References
150:haplotypes
40:Kfarmishki
123:crucifers
58:in 1965.
34:Education
908:aibs.org
855:11586363
812:11546871
726:10576728
691:10576728
521:13003917
451:10715315
402:10712893
357:June 28,
334:21173841
190:Capsella
179:Brassica
162:receptor
142:Brassica
110:Brassica
79:crucifer
835:Bibcode
792:Bibcode
784:Science
769:2114625
749:Bibcode
741:Science
706:Science
671:Science
656:1681543
624:Bibcode
572:4174539
552:Bibcode
529:7071084
501:Bibcode
472:: 467.
442:1464689
382:Bibcode
325:2989624
281:28 June
256:28 June
138:alleles
94:h-index
44:Lebanon
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158:pollen
154:stigma
127:pistil
119:pistil
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101:pollen
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517:PMID
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359:2024
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283:2024
258:2024
156:and
843:doi
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.