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Silybum marianum

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Milk thistle is an upright herb that can grow to be 30 to 200 cm (12 to 79 in) tall and has an overall conical shape. The approximate maximum base diameter is 160 cm (63 in). The stem is grooved and may be covered in a light cottony fuzz. The largest specimens have hollow stems.
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Andrzejewska, Jadwiga, Katarzyna Sadowska, und Sebastian Mielcarek. „Effect of sowing date and rate on the yield and flavonolignan content of the fruits of milk thistle (Silybum marianum L. Gaertn.) grown on light soil in a moderate climate“. Industrial Crops and Products 33, Nr. 2 (2011):
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complex) and 20–35% fatty acids, including linoleic acid. Silymarin is a complex mixture of polyphenolic molecules, including seven closely related flavonolignans (silybin A, silybin B, isosilybin A, isosilybin B, silychristin, isosilychristin, silydianin) and one flavonoid
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establishes itself in sunny, warm ruderal meadows in regularly disturbed places such as rubble deposits, at the foot of south-exposed walls or villages and on urban fallow land or on cattle pastures. However, it does not prefer dry, stony soils.
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The flower heads are 4 to 12 cm long and wide, of red-purple colour. They flower from June to August in the North or December to February in the Southern Hemisphere (summer through autumn). The flower head is surround by
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Veprikova Z, Zachariasova M, Dzuman Z, Zachariasova A, Fenclova M, Slavikova P, Vaclavikova M, Mastovska K, Hengst D, Hajslova J (2015). "Mycotoxins in Plant-Based Dietary Supplements: Hidden Health Risk for Consumers".
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Karkanis, Anestis, Dimitrios Bilalis, und Aspasia Efthimiadou. „Cultivation of Milk Thistle (Silybum Marianum L. Gaertn.), a Medicinal Weed“. Industrial Crops and Products 34, Nr. 1 (1. Juli 2011): 825–30.
296:. This fairly typical thistle has red to purple flowers and shiny pale green leaves with white veins. Originally a native of Southern Europe through to Asia, it is now found throughout the world. 1158:
Hogan, Fawn S.; Krishnegowda, Naveen K.; Mikhailova, Margarita; Kahlenberg, Morton S. (2007). "Flavonoid, Silibinin, Inhibits Proliferation and Promotes Cell-Cycle Arrest of Human Colon Cancer".
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Qavami, N., BADI H. NAGHDI, M. R. Labbafi, und A. Mehrafarin. „A review on pharmacological, cultivation and biotechnology aspects of milk thistle (Silybum marianum (L.) Gaertn.)“, 2013.
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that it has any medicinal effect, and the quality of research has been poor. Silymarin is extracted from the milk thistle seeds and available as a standardized extract. In 2019,
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Zheljazkov, Valtcho D., Ivan Zhalnov, und Nedko K. Nedkov. „Herbicides for weed control in blessed thistle (Silybum marianum)“. Weed technology 20, Nr. 4 (2006): 1030–1034.
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is applied before sowing, to improve yields. Harvest normally occurs in July or August. Since the flower heads don't ripen evenly, optimal harvest time is about a
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stated: "We need a lot more research with reliable clinical trials before we can be sure that milk thistle will play any part in treating or preventing cancers."
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Milk thistle has been potentially observed to modify fire regimes in its invasive range. Its invasion into new habitats may also be encouraged by fire.
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ranges from 5.5 to 7.6, but a wide range is acceptable. The seeds are directly sown into the soil with a sowing depth of 1 to 1.5 cm. For
2550: 2545: 1319: 773: 38: 440:, which simplifies cultivation. When the main requirements of the plant are met, then the milk thistle will blossom in the first year. 1840: 917: 738: 2520: 2452: 2261: 2515: 2364: 1951: 2555: 2540: 2510: 2505: 2225: 2031: 2395: 2129: 1995: 2535: 2052: 1595: 971: 580:, the bacteria in the animal's stomach breaks the chemical down, producing nitrite ions. Nitrite ions then combine with 2490: 2312: 2176: 1977: 1735: 1636: 1461: 705: 1421: 608: 972:"CATALINA ISLAND'S INVASIVE PLANT MANAGEMENT PROGRAM, WITH AN EMPHASIS ON INVASION AND PROTECTION OF OAK ECOSYSTEMS" 2525: 2495: 2413: 2230: 2163: 1485: 2070: 2485: 2026: 1632: 701: 336: 455:
is not necessarily needed because of the low nutrient requirements. A standard fertilization rate of 50 kg
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The highest mycotoxin concentrations were found in milk thistle-based supplements (up to 37 mg/kg in the sum).
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Lambert, Adam; D'antonio, Carla; Dudley, Tom (2010). "Invasive species and fire in California ecosystems".
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content, the plant has been found to be toxic to cattle and sheep. When potassium nitrate is eaten by
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Bhattacharya, Sanjib (2011-01-01), Preedy, Victor R.; Watson, Ronald Ross; Patel, Vinood B. (eds.),
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concentrations of up to 37 mg/kg when compared to various plant-based dietary supplements.
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weed. It also spreads invasively in almost all of Europe as a consequence of field cultivation.
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which are hairless, with triangular, spine-edged appendages, tipped with a stout yellow spine.
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Traditional milk thistle extract is made from the seeds, which contain approximately 4–6%
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Milk thistle has low soil nutrient requirements and is drought resistant. The optimal
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Milk thistle is an adaptive crop with low requirements. It is mainly cultivated as a
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Pflanzensoziologische Exkursionsflora für Deutschland und angrenzende Gebiete
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but it is also sometimes used as a food source. It's mainly cultivated in
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The leaves are oblong to lanceolate and 15–60 cm long and typically
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Milk thistle based supplements have been measured to have the highest
1933: 912:(8., stark überarb. und erg. Aufl ed.). Stuttgart. p. 967. 483: 476: 421: 379: 332: 31: 1662: 521:, a semipurified fraction of silymarin, is primarily a mixture of 2 2369: 1832: 621: 493: 363: 325: 303: 80: 30:"Blessed milk thistle" redirects here. For "blessed thistle", see 1956: 981:. Proceedings of an on-island workshop, February 2–4, 2007: 35–46 1446: 425: 1819: 1666: 1450: 475:
after 50% of the flower heads are dry. For harvesting a common
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outside its natural range, for example into North America,
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Greenlee, H.; Abascal, K.; Yarnell, E.; Ladas, E. (2007).
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Use of milk thistle may cause stomach upset and produce
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Tucker JM, et al. Nitrate Poisoning in Livestock (1961)
1073:"Clinical Applications of Silybum marianum in Oncology" 660:. Greensboro, North Carolina: National Plant Data Team 27:
Species of plant of genus Silybum in family Asteraceae
508:. The extract consists of about 65–80% silymarin (a 2277: 1675: 1608: 1578: 1525: 1516: 1484: 1117:Kroll, D. J.; Shaw, H. S.; Oberlies, N. H. (2007). 1002:"ELEMENT STEWARDSHIP ABSTRACT for Silybum marianum" 525:, silybin A and silybin B, in a roughly 1:1 ratio. 37:"Milk thistle" redirects here. For other uses, see 723: 721: 719: 717: 715: 686:Flora of North America Editorial Committee (ed.). 1401:http://ucanr.edu/sites/UCCE_LR/files/180507.pdf 1314:, San Diego: Academic Press, pp. 759–766, 1312:Nuts and Seeds in Health and Disease Prevention 730:Flora of Australia Volume 37 : Asteraceae 1462: 1031:https://doi.org/10.1016/j.indcrop.2011.03.027 8: 697:Flora of North America North of Mexico (FNA) 1255:The Cochrane Database of Systematic Reviews 1663: 1522: 1469: 1455: 1447: 1365:Journal of Agricultural and Food Chemistry 1024: 1022: 846:Catálogo de plantas y líquenes de Colombia 54: 45: 1274: 1134: 1088: 954: 1191: 1189: 1112: 1110: 1108: 796:. Fraser Valley Invasive Species Society 618:Botanical Society of Britain and Ireland 529:Traditional medicine and adverse effects 1249:Rambaldi A, Jacobs BP, Gluud C (2007). 600: 533:Although milk thistle has been used in 366:; in Africa it reaches as far south as 883: 881: 733:. Melbourne: CSIRO Publishing. 2015. 681: 679: 677: 675: 658:The PLANTS Database (plants.usda.gov) 7: 2406:0acb6e75-049a-49a0-8378-7479545e2a16 2231:a77e05fe-9988-4717-9c55-9b83dde11966 2081:51ed3cc3-7c82-4152-bb8d-efcc33f9eda3 1539:Antiemetics/gastroprokinetic agents: 1428:UC Davis profile for blessed thistle 39:List of plants known as milk thistle 768:. Frederick Warne. pp. 388–9. 889:"Silybum marianum // Mariendistel" 25: 843:Bernal; Gradstein; Celis (2019). 2531:Flora of the Indian subcontinent 2419:urn:lsid:ipni.org:names:188813-1 2169:urn:lsid:ipni.org:names:249211-1 1415: 1343:. Cancer Research UK. 9 May 2019 272:(though not to be confused with 67: 1341:"Milk thistle and liver cancer" 2501:Flora of the Arabian Peninsula 1267:10.1002/14651858.CD003620.pub3 1: 1596:Thyrotropin-releasing hormone 906:Oberdorfer, Erich (c. 2001). 436:, it is normally grown as an 2551:Flora of Southwestern Europe 2546:Flora of Southeastern Europe 1616:Breast development inducers: 1160:Journal of Surgical Research 1123:Integrative Cancer Therapies 1077:Integrative Cancer Therapies 825:. Royal Botanic Gardens, Kew 1637:medroxyprogesterone acetate 1486:Prolactin receptor agonists 979:Catalina Island Conservancy 706:Harvard University Herbaria 537:for centuries, there is no 2577: 1218:Rainone, Francine (2005). 823:Plants of the World Online 394:where it is considered an 262:Mediterranean milk thistle 36: 29: 1224:American Family Physician 1172:10.1016/j.jss.2007.03.080 702:Missouri Botanical Garden 335:with a simple long white 213: 206: 191: 184: 64:Scientific classification 62: 53: 48: 1503:Human placental lactogen 1377:10.1021/acs.jafc.5b02105 1136:10.1177/1534735407301825 1090:10.1177/1534735407301727 1007:. The Nature Conservancy 343:Distribution and habitat 2521:Flora of Eastern Europe 2516:Flora of Middle Europe 1649:Milk letdown inducers: 704:, St. Louis, MO & 501: 358:and much of Europe to 309: 284:). This species is an 2556:Flora of Western Asia 2541:Flora of North Africa 2511:Flora of Central Asia 2506:Flora of the Caucasus 497: 432:. Milk thistle is a 331:The fruits are black 307: 2536:Flora of Macaronesia 1531:receptor antagonists 1424:at Wikimedia Commons 970:Knapp, John (2010). 535:traditional medicine 292:plant of the family 258:Saint Mary's thistle 1641:cyproterone acetate 1518:Prolactin releasers 1439:Plants for a Future 766:The Wild Flower Key 275:Onopordum acanthium 246:blessed milkthistle 2491:Christian folklore 1434:"Silybum marianum" 861:"Silybum marianum" 590:oxygen deprivation 550:allergic reactions 543:Cancer Research UK 502: 310: 266:variegated thistle 236:. It has various 2526:Flora of Ethiopia 2496:CYP3A4 inhibitors 2468: 2467: 2115:Open Tree of Life 1669:Taxon identifiers 1660: 1659: 1604: 1603: 1420:Media related to 1321:978-0-12-375688-6 775:978-0-7232-2419-8 652:Silphium marianum 539:clinical evidence 480:combine harvester 225: 224: 220: 16:(Redirected from 2568: 2486:Medicinal plants 2461: 2460: 2448: 2447: 2435: 2434: 2422: 2421: 2409: 2408: 2399: 2398: 2386: 2385: 2373: 2372: 2360: 2359: 2347: 2346: 2334: 2333: 2321: 2320: 2308: 2307: 2298: 2297: 2296: 2279:Carduus marianus 2270: 2269: 2257: 2256: 2244: 2243: 2234: 2233: 2221: 2220: 2211: 2210: 2198: 2197: 2185: 2184: 2172: 2171: 2159: 2158: 2146: 2145: 2133: 2132: 2123: 2122: 2110: 2109: 2097: 2096: 2084: 2083: 2074: 2073: 2061: 2060: 2058:NHMSYS0000463605 2048: 2047: 2035: 2034: 2022: 2021: 2012: 2011: 1999: 1998: 1986: 1985: 1973: 1972: 1960: 1959: 1947: 1946: 1937: 1936: 1924: 1923: 1911: 1910: 1898: 1897: 1888: 1887: 1885:Silybum marianum 1875: 1874: 1862: 1861: 1849: 1848: 1836: 1835: 1823: 1822: 1810: 1809: 1797: 1796: 1784: 1783: 1781:silybum-marianum 1774: 1773: 1764: 1763: 1754: 1753: 1744: 1743: 1731: 1730: 1721: 1720: 1711: 1710: 1709: 1707:Silybum marianum 1696: 1695: 1694: 1677:Silybum marianum 1664: 1523: 1471: 1464: 1457: 1448: 1443: 1422:Silybum marianum 1419: 1404: 1398: 1392: 1391: 1359: 1353: 1352: 1350: 1348: 1337: 1331: 1330: 1329: 1328: 1303: 1297: 1296: 1278: 1246: 1240: 1239: 1215: 1209: 1208: 1206: 1204: 1193: 1184: 1183: 1155: 1149: 1148: 1138: 1114: 1103: 1102: 1092: 1068: 1062: 1058: 1052: 1049: 1043: 1040: 1034: 1026: 1017: 1016: 1014: 1012: 1006: 997: 991: 990: 988: 986: 976: 967: 961: 960: 958: 938: 932: 931: 903: 897: 896: 885: 876: 875: 873: 871: 857: 851: 850: 840: 834: 833: 831: 830: 818:Silybum marianum 812: 806: 805: 803: 801: 786: 780: 779: 758: 752: 751: 749: 747: 725: 710: 709: 708:, Cambridge, MA. 690:Silybum marianum 683: 670: 669: 667: 665: 642: 636: 635: 633: 632: 626: 620:. Archived from 615: 605: 552:in some people. 523:diastereoisomers 482:can be used. In 402:Silybum marianum 374:has been widely 354:from around the 348:Silybum marianum 232:is a species of 229:Silybum marianum 218: 216:Carduus marianus 197: 195:Silybum marianum 177:S. marianum 72: 71: 58: 46: 21: 2576: 2575: 2571: 2570: 2569: 2567: 2566: 2565: 2471: 2470: 2469: 2464: 2456: 2451: 2443: 2438: 2430: 2425: 2417: 2412: 2404: 2402: 2394: 2389: 2381: 2376: 2368: 2363: 2355: 2350: 2342: 2337: 2329: 2324: 2316: 2311: 2303: 2301: 2292: 2291: 2286: 2273: 2265: 2260: 2252: 2247: 2239: 2237: 2229: 2224: 2216: 2214: 2206: 2201: 2193: 2188: 2180: 2175: 2167: 2162: 2154: 2149: 2141: 2136: 2128: 2126: 2118: 2113: 2105: 2102:Observation.org 2100: 2092: 2087: 2079: 2077: 2069: 2064: 2056: 2051: 2043: 2038: 2030: 2025: 2017: 2016:MichiganFlora: 2015: 2007: 2002: 1994: 1989: 1981: 1976: 1968: 1963: 1955: 1950: 1942: 1940: 1932: 1927: 1919: 1914: 1906: 1901: 1893: 1891: 1883: 1878: 1870: 1865: 1857: 1852: 1844: 1839: 1831: 1826: 1818: 1813: 1805: 1800: 1792: 1787: 1779: 1777: 1769: 1767: 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Gaertn. 194: 192: 176: 175: 163: 126: 113: 100: 87: 43: 18:Milk Thistle 2040:NatureServe 1929:iNaturalist 1701:Wikispecies 1562:Risperidone 1542:Domperidone 664:15 November 584:to produce 572:Because of 449:germination 412:Cultivation 388:New Zealand 372:S. marianum 300:Description 107:Angiosperms 2475:Categories 2143:gcc-114114 2138:Plant List 1768:Calflora: 1327:2021-12-02 1203:20 October 829:2023-04-29 800:24 January 646:USDA, NRCS 631:2014-10-17 596:References 582:hemoglobin 461:phosphorus 376:introduced 294:Asteraceae 240:including 153:Asteraceae 2294:Q21872176 1872:200024549 1854:FloraBase 1778:Cal-IPC: 1623:estradiol 1619:Estrogens 1586:Estrogens 1567:Sulpiride 1508:Prolactin 951:CiteSeerX 943:Fremontia 865:plantpono 578:ruminants 562:mycotoxin 519:Silibinin 515:taxifolin 506:silymarin 499:Silibinin 490:Chemistry 473:fortnight 465:potassium 384:Australia 171:Species: 143:Asterales 77:Kingdom: 2427:Tropicos 2383:10203217 2370:188813-1 2288:Wikidata 2226:VicFlora 2215:VASCAN: 2203:Tropicos 2045:2.143221 1970:11113162 1758:BioLib: 1751:286-4-1a 1686:Wikidata 1652:Oxytocin 1385:26168136 1347:9 August 1293:41057368 1285:17943794 1236:16225032 1180:17950073 1145:17548790 1099:17548794 1061:462–468. 1011:9 August 985:9 August 928:50980051 870:9 August 764:(1981). 746:9 August 648:(n.d.). 556:Toxicity 457:nitrogen 396:invasive 392:Colombia 368:Ethiopia 290:biennial 208:Synonyms 149:Family: 133:Asterids 120:Eudicots 2481:Silybum 2458:1173071 2432:2716926 2344:3145219 2267:1106175 2208:2711064 2027:MoBotPF 1957:91418-3 1908:3145214 1802:Ecocrop 1692:Q193798 1631:(e.g., 1621:(e.g., 1276:8724782 574:nitrate 469:hectare 333:achenes 234:thistle 164:Silybum 159:Genus: 139:Order: 81:Plantae 2403:NZOR: 2396:510125 2318:109222 2305:100810 2302:APDB: 2195:2961-1 2151:PLANTS 2120:650188 2078:NZOR: 2032:277472 2009:202991 1895:silmar 1892:FoIO: 1846:159640 1820:509366 1748:APSA: 1725:APDB: 1609:Others 1579:Others 1571:Others 1383:  1318:  1291:  1283:  1273:  1234:  1178:  1143:  1097:  953:  926:  916:  772:  737:  484:Poland 477:cereal 422:Europe 390:, and 380:Hawaii 352:native 337:pappus 326:bracts 286:annual 32:Cnicus 2453:WoRMS 2378:IRMNG 2262:WoRMS 2238:WoI: 2190:SANBI 2182:17359 2156:SIMA3 2127:PFI: 2089:NZPCN 2071:92921 1996:38413 1983:50304 1965:IRMNG 1941:IPA: 1934:52586 1921:33952 1880:FoAO2 1841:EUNIS 1833:SLYMA 1794:6YPNF 1761:41396 1741:76429 1728:95141 1715:APA: 1289:S2CID 1005:(PDF) 975:(PDF) 625:(xls) 614:(xls) 364:India 127:Clade 114:Clade 101:Clade 88:Clade 2414:POWO 2391:ITIS 2365:IPNI 2357:9022 2352:GRIN 2339:GBIF 2331:R6XP 2313:APNI 2218:3434 2164:POWO 2130:5927 2107:7468 2094:2766 2066:NCBI 2004:IUCN 1991:ITIS 1952:IPNI 1944:4462 1916:GRIN 1903:GBIF 1859:8227 1828:EPPO 1807:9784 1771:7622 1736:APNI 1381:PMID 1349:2020 1316:ISBN 1281:PMID 1259:2009 1232:PMID 1205:2020 1176:PMID 1141:PMID 1095:PMID 1013:2020 987:2020 924:OCLC 914:ISBN 872:2020 802:2021 770:ISBN 748:2020 735:ISBN 666:2015 467:per 428:and 426:Asia 362:and 268:and 2440:WFO 2326:CoL 2249:WFO 2177:RHS 2053:NBN 2019:449 1978:ISC 1867:FNA 1815:EoL 1789:CoL 1718:971 1373:doi 1271:PMC 1263:doi 1168:doi 1164:143 1131:doi 1085:doi 517:). 350:is 288:or 278:or 2477:: 2455:: 2442:: 2429:: 2416:: 2393:: 2380:: 2367:: 2354:: 2341:: 2328:: 2315:: 2290:: 2264:: 2251:: 2241:75 2228:: 2205:: 2192:: 2179:: 2166:: 2153:: 2140:: 2117:: 2104:: 2091:: 2068:: 2055:: 2042:: 2029:: 2006:: 1993:: 1980:: 1967:: 1954:: 1931:: 1918:: 1905:: 1882:: 1869:: 1856:: 1843:: 1830:: 1817:: 1804:: 1791:: 1738:: 1703:: 1688:: 1639:, 1635:, 1436:. 1387:. 1379:. 1369:63 1367:. 1310:, 1287:. 1279:. 1269:. 1257:. 1253:. 1228:72 1226:. 1222:. 1188:^ 1174:. 1162:. 1139:. 1125:. 1121:. 1107:^ 1093:. 1079:. 1075:. 1021:^ 977:. 947:38 945:. 922:. 891:. 880:^ 863:. 792:. 714:^ 694:. 674:^ 656:. 616:. 592:. 445:pH 386:, 382:, 264:, 260:, 256:, 252:, 248:, 244:, 219:L. 129:: 116:: 103:: 90:: 1643:) 1625:) 1529:2 1527:D 1496:/ 1470:e 1463:t 1456:v 1442:. 1375:: 1351:. 1295:. 1265:: 1238:. 1207:. 1182:. 1170:: 1147:. 1133:: 1127:6 1101:. 1087:: 1081:6 1033:. 1015:. 989:. 959:. 930:. 895:. 874:. 832:. 816:" 804:. 778:. 750:. 692:" 688:" 668:. 654:" 650:" 634:. 513:( 41:. 34:. 20:)

Index

Milk Thistle
Cnicus
List of plants known as milk thistle

Scientific classification
Edit this classification
Plantae
Tracheophytes
Angiosperms
Eudicots
Asterids
Asterales
Asteraceae
Silybum
Binomial name
Synonyms
thistle
common names
Onopordum acanthium
Cirsium vulgare
annual
biennial
Asteraceae

pinnately lobed
bracts
achenes
pappus
native
Mediterranean

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