255:
180:
47:
410:
481:
477:
38:
724:
560:
480:
418:
390:
525:
498:
573:
482:
483:
768:
763:[Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese).
538:
304:
756:
269:
633:
510:
792:(2022 ed.). United States Department of Justice Drug Enforcement Administration Office of Diversion Control. May 9, 2014.
893:
812:
764:
760:
580:
446:
212:
233:
409:
491:
888:
129:
761:"RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial"
744:
674:-Phenethyl-4-piperidinone is useful in the synthesis of addictive drugs, primarily fentanyl and its analogs.
660:
175:
679:
637:
432:
402:
640:
in 2007. Both domestic sales and domestic importations are thus subject to DEA reporting requirements.
883:
656:
59:
250:
46:
619:
456:
95:
856:
711:
699:
687:
804:
848:
607:
878:
840:
327:
221:
157:
105:
254:
179:
17:
831:
Beckett AH, Casy AF, Kirk G (February 1959). "Alpha- and beta-prodine type compounds".
683:
652:
603:
551:
37:
872:
630:
375:
168:
860:
675:
452:
201:
723:
355:
148:
852:
715:
623:
497:
490:
463:
278:
InChI=1S/C13H17NO/c15-13-7-10-14(11-8-13)9-6-12-4-2-1-3-5-12/h1-5H,6-11H2
844:
629:
Because of its possible use in the illicit manufacture of fentanyl, the
288:
InChI=1/C13H17NO/c15-13-7-10-14(11-8-13)9-6-12-4-2-1-3-5-12/h1-5H,6-11H2
695:
365:
188:
790:
DEA Chemical
Handler's Manual: A Guide to Chemical Control Regulations
618:
NO. It is used as an intermediate in the manufacture of chemicals and
703:
550:
Except where otherwise noted, data are given for materials in their
438:
128:
118:
238:
519:
475:
380:
56 to 60 °C (133 to 140 °F; 329 to 333 K)
532:
568:
686:. The Siegfried method (shown below and published on
73:1-Phenethylpiperidin-4-one (no longer recommended)
833:Journal of Medicinal and Pharmaceutical Chemistry
200:
651:-Phenethyl-4-piperidinone can be prepared from
479:
104:
8:
698:, and then reducing the imine product with
682:) first synthesized fentanyl in 1960 from
253:
178:
156:
26:
659:in biphasic conditions with a variety of
220:
736:
309:
274:
249:
169:
710:(ANPP). This product is reacted with
636:(DEA) placed NPP under control as a
281:Key: YDJXNYNKKXZBMP-UHFFFAOYSA-N
7:
291:Key: YDJXNYNKKXZBMP-UHFFFAOYAQ
191:
25:
722:
558:
408:
345:
339:
64:1-(2-Phenylethyl)piperidin-4-one
45:
36:
813:Chemical & Engineering News
771:from the original on 2023-08-03
694:-phenethyl-4-piperidinone with
634:Drug Enforcement Administration
554:(at 25 °C , 100 kPa).
348:
333:
1:
809:List of Top Pharmaceuticals
78:-Phenylethyl-4-piperidinone
910:
360:203.28 g/mol
31:-Phenethyl-4-piperidinone
596:-Phenethyl-4-piperidinone
548:
389:
384:
320:
300:
265:
88:
70:
58:
53:
44:
35:
767:(published 2023-04-04).
661:phase transfer catalysts
447:Precautionary statements
18:N-phenethyl-4-piperidone
765:Diário Oficial da União
83:-Phenethyl-4-piperidone
528:(Prohibited substance)
486:
312:O=C2CCN(CCc1ccccc1)CC2
894:Janssen Pharmaceutica
680:Janssen Pharmaceutica
602:) is a derivative of
485:
708:-phenethylpiperidine
690:) involves reacting
620:pharmaceutical drugs
468:(fire diamond)
60:Preferred IUPAC name
845:10.1021/jm50002a004
32:
712:propionyl chloride
700:sodium borohydride
581:Infobox references
487:
27:
657:phenethyl bromide
608:molecular formula
589:Chemical compound
587:
586:
541:(Drug precursors)
536:
523:
433:Hazard statements
234:CompTox Dashboard
130:Interactive image
16:(Redirected from
901:
864:
817:
816:
800:
794:
793:
786:
780:
779:
777:
776:
753:
747:
741:
726:
571:
565:
562:
561:
534:
531:
521:
518:
500:
493:
478:
458:
454:
440:
412:
350:
347:
341:
335:
328:Chemical formula
258:
257:
242:
240:
224:
204:
193:
182:
171:
160:
132:
108:
49:
40:
33:
21:
909:
908:
904:
903:
902:
900:
899:
898:
889:Phenethylamines
869:
868:
867:
830:
826:
824:Further reading
821:
820:
802:
801:
797:
788:
787:
783:
774:
772:
755:
754:
750:
742:
738:
733:
669:
646:
638:List 1 Chemical
617:
613:
590:
583:
578:
577:
576: ?)
567:
563:
559:
555:
544:
505:
504:
503:
502:
495:
488:
484:
476:
449:
435:
421:
405:
344:
338:
330:
316:
313:
308:
307:
296:
293:
292:
289:
283:
282:
279:
273:
272:
261:
243:
236:
227:
207:
194:
163:
135:
122:
111:
98:
84:
79:
74:
66:
65:
23:
22:
15:
12:
11:
5:
907:
905:
897:
896:
891:
886:
881:
871:
870:
866:
865:
827:
825:
822:
819:
818:
795:
781:
759:(2023-03-31).
748:
735:
734:
732:
729:
728:
727:
684:Benzylfentanyl
668:
665:
653:4-piperidinone
645:
642:
615:
611:
604:4-piperidinone
588:
585:
584:
579:
557:
556:
552:standard state
549:
546:
545:
543:
542:
529:
515:
513:
507:
506:
496:
489:
474:
473:
472:
471:
469:
460:
459:
450:
445:
442:
441:
436:
431:
428:
427:
422:
417:
414:
413:
406:
401:
398:
397:
387:
386:
382:
381:
378:
372:
371:
368:
362:
361:
358:
352:
351:
342:
336:
331:
326:
323:
322:
318:
317:
315:
314:
311:
303:
302:
301:
298:
297:
295:
294:
290:
287:
286:
284:
280:
277:
276:
268:
267:
266:
263:
262:
260:
259:
251:DTXSID30192826
246:
244:
232:
229:
228:
226:
225:
217:
215:
209:
208:
206:
205:
197:
195:
187:
184:
183:
173:
165:
164:
162:
161:
153:
151:
145:
144:
141:
140:Abbreviations
137:
136:
134:
133:
125:
123:
116:
113:
112:
110:
109:
101:
99:
94:
91:
90:
86:
85:
72:
68:
67:
63:
62:
56:
55:
51:
50:
42:
41:
24:
14:
13:
10:
9:
6:
4:
3:
2:
906:
895:
892:
890:
887:
885:
882:
880:
877:
876:
874:
862:
858:
854:
850:
846:
842:
838:
834:
829:
828:
823:
814:
810:
806:
799:
796:
791:
785:
782:
770:
766:
762:
758:
752:
749:
746:
740:
737:
730:
725:
721:
720:
719:
717:
713:
709:
707:
701:
697:
693:
689:
685:
681:
677:
673:
666:
664:
662:
658:
654:
650:
643:
641:
639:
635:
632:
631:United States
627:
625:
621:
609:
605:
601:
597:
595:
582:
575:
570:
553:
547:
540:
530:
527:
517:
516:
514:
512:
509:
508:
501:
494:
470:
467:
466:
462:
461:
451:
448:
444:
443:
437:
434:
430:
429:
426:
423:
420:
416:
415:
411:
407:
404:
400:
399:
395:
393:
388:
383:
379:
377:
376:Melting point
374:
373:
369:
367:
364:
363:
359:
357:
354:
353:
332:
329:
325:
324:
319:
310:
306:
299:
285:
275:
271:
264:
256:
252:
248:
247:
245:
235:
231:
230:
223:
219:
218:
216:
214:
211:
210:
203:
199:
198:
196:
190:
186:
185:
181:
177:
174:
172:
170:ECHA InfoCard
167:
166:
159:
155:
154:
152:
150:
147:
146:
142:
139:
138:
131:
127:
126:
124:
120:
115:
114:
107:
103:
102:
100:
97:
93:
92:
87:
82:
77:
69:
61:
57:
52:
48:
43:
39:
34:
30:
19:
839:(1): 37–58.
836:
832:
808:
798:
789:
784:
773:. Retrieved
751:
739:
705:
691:
678:(founder of
676:Paul Janssen
671:
670:
648:
647:
628:
599:
593:
592:
591:
511:Legal status
464:
424:
391:
89:Identifiers
80:
75:
71:Other names
28:
884:Piperidines
644:Preparation
419:Signal word
370:1.057 g/cm
321:Properties
176:100.049.630
873:Categories
805:"Fentanyl"
803:Schulz W.
775:2023-08-15
731:References
704:4-anilino-
403:Pictograms
356:Molar mass
222:CIS0S4O95K
149:ChemSpider
117:3D model (
106:39742-60-4
96:CAS Number
606:with the
394:labelling
861:42058755
853:13655028
769:Archived
716:fentanyl
714:to form
688:The Hive
624:fentanyl
622:such as
539:Class D1
465:NFPA 704
385:Hazards
879:Ketones
745:PubChem
696:aniline
574:what is
572: (
425:Warning
366:Density
189:PubChem
859:
851:
757:Anvisa
569:verify
566:
537:
524:
305:SMILES
54:Names
857:S2CID
743:GHS:
270:InChI
202:96437
158:87058
119:JSmol
849:PMID
667:Uses
655:and
457:P270
453:P264
439:H302
213:UNII
143:NPP
841:doi
702:to
626:.
600:NPP
392:GHS
239:EPA
192:CID
875::
855:.
847:.
835:.
811:.
807:.
718:.
663:.
616:17
612:13
533:BR
526:S9
520:AU
455:,
396::
343:17
337:13
863:.
843::
837:1
815:.
778:.
706:N
692:N
672:N
649:N
614:H
610:C
598:(
594:N
564:Y
535::
522::
499:3
492:1
349:O
346:N
340:H
334:C
241:)
237:(
121:)
81:N
76:N
29:N
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
