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169:(IRCM) since 1974. He is the director of the laboratory of Biochemical Neuroendocrinology. He discovered and cloned seven (PC1, PC2, PC4, PC5, PC7, SKI-1 and PCSK9) of the nine known enzymes belonging to the convertase family. During this period, he also greatly contributed to demonstrating that the
189:, likely because of a gain of function related to the ability of PCSK9 to enhance the degradation of cell surface receptors, such as the low-density lipoprotein receptor (LDLR). He has since worked on the elucidation of the functions and mechanisms of action of PCSK9 and
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1999 - Medal of Honor, Pharmaceutical
Manufacturers Association of Canada (PMAC) Health Research Foundation
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both in cells and in vivo, and is developing specific PCSK9 and PCSK7 inhibitors/silencers.
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2014 - Jacques Genest Award from the
Canadian Society of Endocrinology & Metabolism
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2009 - Pfizer
Distinguished Cardiovascular-Metabolic Research Jean-Davignon Award
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is a wide mechanism that also concerns “non-neuropeptide” proteins such as
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2016 - CIHR Distinguished
Lecturer Award in Cardiovascular Sciences
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2021 - Elected member of the
Canadian Academy of Health Sciences
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2013 - Simon Pierre-Noël
Memorial Lecture Award in Lipid Research
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1995 - Medical
Research Council Distinguished Scientist Award
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Grand Prix scientifique de la
Fondation Lefoulon-Delalande
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2003-2024 - Canada Chair Tier 1 in
Precursor Proteolysis
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where he obtained his Ph.D. in 1973. He emigrated to
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202:1977 - The Clarke Institute of Psychiatry Award
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463:This article about a Canadian scientist is a
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275:2015 - Anne and Neil McArthur Research Award
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549:Officers of the National Order of Quebec
265:Queen Elizabeth II Diamond Jubilee Medal
393:Clinical Research Institute of Montreal
332:International Consortium on Anti-Virals
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167:Clinical Research Institute of Montreal
117:Clinical Research Institute of Montreal
539:Fellows of the Royal Society of Canada
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414:"Nabil G. Seidah, C.M., O.Q., Ph.D."
217:1994 - Manning Award of Distinction
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574:21st-century Canadian scientists
569:20th-century Canadian scientists
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260:in Biomedical Research in Québec
544:Members of the Order of Canada
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187:familial hypercholesterolemia
559:Georgetown University alumni
467:. You can help Knowledge by
165:and has been working at the
223:1997 - Made Officer of the
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417:Governor General of Canada
229:1999 - Made member of the
211:1991 - Made Fellow of the
145:(born 1949) is a Canadian
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579:Canadian scientist stubs
524:Scientists from Montreal
225:Ordre national du Québec
554:Cairo University alumni
360:Royal Society of Canada
356:"Nabil G. Seidah, FRSC"
213:Royal Society of Canada
389:"Director's biography"
175:proprotein convertases
157:, and subsequently at
258:Wilder-Penfield Prize
244:2001 - Winner of the
238:2001 - Winner of the
159:Georgetown University
153:, he was educated at
86:Proprotein convertase
76:Georgetown University
564:Canadian biochemists
185:gene cause dominant
529:Egyptian scientists
149:scientist. Born in
246:LĂ©o-Pariseau Prize
207:Marcel-Piché Prize
16:Canadian scientist
534:Egyptian chemists
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328:"Nabil G. Seidah"
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97:Scientific career
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362:. Archived from
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231:Order of Canada
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396:. Retrieved
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368:. Retrieved
364:the original
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335:. Retrieved
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296:Lucian Award
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113:Institutions
107:Biochemistry
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23:Nabil Seidah
514:1949 births
422:26 December
398:26 December
370:26 December
337:26 December
171:proteolysis
58:Nationality
508:Categories
305:References
289:Akira Endo
147:Québécois
62:Canadian
294:2018 -
287:2018 -
281:2018 -
263:2013 -
256:2011 -
205:1983 -
173:by the
197:Awards
163:Canada
103:Fields
291:Award
191:PCSK7
183:PCSK9
151:Egypt
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90:PCSK9
51:Egypt
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465:stub
424:2010
400:2010
372:2010
339:2010
142:FRSC
47:1949
44:Born
36:FRSC
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