402:
379:
133:
25:
812:
David A, Leith-Ross F, Vallance DK (July 1957). "Antitussive and other pharmacological properties of the diethylaminoethoxyethyl ester of alpha alpha-diethylphenylacetic acid, (oxeladin)".
882:
163:
526:
145:
482:
875:
736:
Oxeladin is available as drops, syrup and tablets, providing easier ways of management which will be chosen depending on the age and clinical stage.
847:
1411:
868:
468:
502:
108:
1470:
196:
46:
1227:
550:. It is a highly potent and effective drug used to treat all types of cough of various etiologies. It is not related to
298:
89:
1460:
1428:
358:
61:
35:
42:
68:
1028:
510:
InChI=1S/C20H33NO3/c1-5-20(6-2,18-12-10-9-11-13-18)19(22)24-17-16-23-15-14-21(7-3)8-4/h9-13H,5-8,14-17H2,1-4H3
1416:
1171:
1167:
954:
950:
397:
965:
681:
571:
347:
75:
1455:
922:
645:
851:
1113:
555:
57:
1258:
1132:
946:
374:
213:
848:"Pharmaceuticals: Restrictions in Use and Availability: Monocomponent products: Oxeladin citrate"
744:
Each 1ml (33 drops) contains oxeladin citrate 20 mg. The bottle contains 20ml of solution.
760:
Each tablet contains oxeladin citrate 20 mg. The box contains 20 tablets in blister packs
1088:
937:
917:
829:
611:
547:
1333:
1192:
1138:
980:
821:
414:
307:
1465:
1293:
1000:
985:
969:
912:
904:
287:
401:
378:
222:
590:
and its derivatives, are used. It may be used at every age, as well as in patients with
1422:
1143:
1118:
1008:
891:
825:
575:
752:
Each 100ml contains oxeladin citrate 200 mg. The bottle contains 100ml of syrup.
82:
1449:
1383:
1368:
1288:
1207:
1187:
1177:
1153:
1023:
975:
728:
or its derivatives) in that there is no evidence of risk of addiction or dependence.
724:
Oxeladin differs from common antitussives that cause addiction (such as etilmorphin,
591:
390:
860:
155:
1303:
1298:
1278:
1248:
1212:
1038:
960:
895:
775:
Children 12 yrs and over and adults: 15ml (50 drops), or 2 tablets, every 4–6 hours
669:
579:
176:
171:
684:
have not been reported, oxeladin should not be used during the first trimester of
638:
247:
1378:
1343:
1253:
1243:
1202:
1163:
1123:
1068:
942:
716:. These usually disappear on reducing the dosage or interrupting the treatment.
607:
563:
132:
24:
1388:
1373:
1353:
1348:
1338:
1328:
1318:
1273:
1268:
1263:
1222:
1148:
1053:
1048:
1043:
1018:
793:
659:
655:
626:
444:
278:
644:
Treatment of cough in patients with heart disease (it has no action upon the
1363:
1313:
1308:
1217:
1197:
1078:
990:
713:
705:
685:
663:
651:
619:
615:
594:, since it has a high level of safety and a great selectivity to act on the
583:
559:
149:
833:
1393:
1323:
1283:
1182:
1073:
1058:
1033:
1013:
932:
709:
567:
258:
124:
267:
1128:
927:
789:
785:
725:
632:
587:
233:
1158:
1102:
595:
338:
788:
rejected the registration of oxeladin in July 2000 since studies in
327:
1097:
1063:
554:
or its derivatives, so treatment with oxeladin is free of risk of
551:
467:
458:
772:
Children 6-12 yrs: 10ml (33 drops), or 1 tablet, every 4–6 hours
701:
689:
318:
864:
796:
of the drug. (Reference: Communication to WHO, 9 August 2000.)
18:
668:
Treatment of cough in pre- and post-operative treatment for
363:
606:
Oxeladin is indicated in all types of cough. Besides its
204:
2-(2-diethylaminoethoxy)ethyl 2-ethyl-2-phenyl-butanoate
533:
586:) which are present when common antitussives, such as
769:
Children 2-5yrs: 2.5ml-5ml (17 drops) every 4–6 hours
1236:
1096:
1087:
999:
903:
456:
443:
413:
408:
389:
357:
337:
317:
297:
277:
257:
232:
212:
187:
162:
144:
139:
49:. Unsourced material may be challenged and removed.
246:
688:. Oxeladin is contraindicated in patients with
221:
876:
8:
123:
1093:
883:
869:
861:
784:The Drug and Medical Technology Agency of
400:
377:
286:
131:
306:
109:Learn how and when to remove this message
814:The Journal of Pharmacy and Pharmacology
804:
507:
487:
373:
266:
201:
391:
122:
614:, since it increases the quantity of
346:
154:
7:
780:Restrictions in use and availability
700:Rarely, some patients have reported
175:
47:adding citations to reliable sources
490:O=C(OCCOCCN(CC)CC)C(c1ccccc1)(CC)CC
326:
237:
826:10.1111/j.2042-7158.1957.tb12297.x
14:
431:
425:
23:
515:Key:IQADUMSPOQKAAO-UHFFFAOYSA-N
34:needs additional citations for
610:action, it helps to clear the
434:
419:
1:
892:Cough and cold preparations
562:. Oxeladin has none of the
1487:
409:Chemical and physical data
1406:
732:Composition and packaging
523:
498:
478:
192:
130:
1029:Dembrexine hydrochloride
156:International Drug Names
1471:Diethylamino compounds
961:Hederae helicis folium
714:digestive disturbances
572:respiratory depression
923:Antimony pentasulfide
792:have shown potential
646:cardiovascular system
1114:Acetyldihydrocodeine
43:improve this article
1259:Bibenzonium bromide
682:fetal malformations
127:
1461:Carboxylate esters
1433:Never to phase III
1089:Cough suppressants
1443:
1442:
1402:
1401:
938:Guaiacolsulfonate
918:Ammonium chloride
676:Contraindications
612:respiratory tract
598:centre of cough.
548:cough suppressant
541:
540:
469:Interactive image
359:CompTox Dashboard
119:
118:
111:
93:
16:Chemical compound
1478:
1334:Levodropropizine
1193:Levopropoxyphene
1139:Dextromethorphan
1094:
981:Potassium iodide
885:
878:
871:
862:
856:
855:
854:on 12 June 2011.
850:. Archived from
844:
838:
837:
809:
537:
536:
529:
471:
451:
436:
433:
427:
421:
404:
393:
382:
381:
367:
365:
350:
330:
310:
290:
270:
250:
240:
239:
225:
179:
158:
135:
128:
126:
114:
107:
103:
100:
94:
92:
51:
27:
19:
1486:
1485:
1481:
1480:
1479:
1477:
1476:
1475:
1446:
1445:
1444:
1439:
1438:
1423:Clinical trials
1398:
1294:Diphenhydramine
1232:
1107:and derivatives
1106:
1101:
1083:
995:
970:Syrup of ipecac
899:
889:
859:
846:
845:
841:
811:
810:
806:
802:
794:carcinogenicity
782:
766:
758:
750:
742:
734:
722:
698:
678:
604:
532:
530:
527:(what is this?)
524:
519:
516:
511:
506:
505:
494:
491:
486:
485:
474:
449:
439:
430:
424:
385:
361:
353:
333:
313:
293:
273:
253:
236:
228:
208:
205:
200:
199:
183:
115:
104:
98:
95:
52:
50:
40:
28:
17:
12:
11:
5:
1484:
1482:
1474:
1473:
1468:
1463:
1458:
1448:
1447:
1441:
1440:
1437:
1436:
1435:
1434:
1431:
1420:
1414:
1408:
1407:
1404:
1403:
1400:
1399:
1397:
1396:
1391:
1386:
1381:
1376:
1371:
1366:
1361:
1356:
1351:
1346:
1341:
1336:
1331:
1326:
1321:
1316:
1311:
1306:
1301:
1296:
1291:
1286:
1281:
1276:
1271:
1266:
1261:
1256:
1251:
1246:
1240:
1238:
1234:
1233:
1231:
1230:
1225:
1220:
1215:
1210:
1205:
1200:
1195:
1190:
1185:
1180:
1175:
1161:
1156:
1151:
1146:
1144:Dihydrocodeine
1141:
1136:
1126:
1121:
1119:Benzylmorphine
1116:
1110:
1108:
1091:
1085:
1084:
1082:
1081:
1076:
1071:
1066:
1061:
1056:
1051:
1046:
1041:
1036:
1031:
1026:
1021:
1016:
1011:
1009:Acetylcysteine
1005:
1003:
997:
996:
994:
993:
988:
983:
978:
973:
963:
958:
940:
935:
930:
925:
920:
915:
909:
907:
901:
900:
890:
888:
887:
880:
873:
865:
858:
857:
839:
803:
801:
798:
781:
778:
777:
776:
773:
770:
765:
762:
757:
754:
749:
746:
741:
738:
733:
730:
721:
718:
697:
694:
677:
674:
673:
672:
666:
649:
642:
636:
630:
603:
600:
539:
538:
521:
520:
518:
517:
514:
512:
509:
501:
500:
499:
496:
495:
493:
492:
489:
481:
480:
479:
476:
475:
473:
472:
464:
462:
454:
453:
447:
441:
440:
437:
428:
422:
417:
411:
410:
406:
405:
395:
387:
386:
384:
383:
370:
368:
355:
354:
352:
351:
343:
341:
335:
334:
332:
331:
323:
321:
315:
314:
312:
311:
303:
301:
295:
294:
292:
291:
283:
281:
275:
274:
272:
271:
263:
261:
255:
254:
252:
251:
243:
241:
230:
229:
227:
226:
218:
216:
210:
209:
207:
206:
203:
195:
194:
193:
190:
189:
185:
184:
182:
181:
168:
166:
160:
159:
152:
142:
141:
137:
136:
117:
116:
31:
29:
22:
15:
13:
10:
9:
6:
4:
3:
2:
1483:
1472:
1469:
1467:
1464:
1462:
1459:
1457:
1454:
1453:
1451:
1432:
1430:
1427:
1426:
1424:
1421:
1418:
1415:
1413:
1410:
1409:
1405:
1395:
1392:
1390:
1387:
1385:
1384:Prenoxdiazine
1382:
1380:
1377:
1375:
1372:
1370:
1369:Pentoxyverine
1367:
1365:
1362:
1360:
1357:
1355:
1352:
1350:
1347:
1345:
1342:
1340:
1337:
1335:
1332:
1330:
1327:
1325:
1322:
1320:
1317:
1315:
1312:
1310:
1307:
1305:
1302:
1300:
1297:
1295:
1292:
1290:
1289:Dimethoxanate
1287:
1285:
1282:
1280:
1277:
1275:
1272:
1270:
1267:
1265:
1262:
1260:
1257:
1255:
1252:
1250:
1247:
1245:
1242:
1241:
1239:
1235:
1229:
1226:
1224:
1221:
1219:
1216:
1214:
1211:
1209:
1208:Nicodicodeine
1206:
1204:
1201:
1199:
1196:
1194:
1191:
1189:
1188:Levomethadone
1186:
1184:
1181:
1179:
1178:Hydromorphone
1176:
1173:
1169:
1165:
1162:
1160:
1157:
1155:
1154:Ethylmorphine
1152:
1150:
1147:
1145:
1142:
1140:
1137:
1134:
1130:
1127:
1125:
1122:
1120:
1117:
1115:
1112:
1111:
1109:
1104:
1099:
1095:
1092:
1090:
1086:
1080:
1077:
1075:
1072:
1070:
1067:
1065:
1062:
1060:
1057:
1055:
1052:
1050:
1047:
1045:
1042:
1040:
1037:
1035:
1032:
1030:
1027:
1025:
1024:Carbocisteine
1022:
1020:
1017:
1015:
1012:
1010:
1007:
1006:
1004:
1002:
998:
992:
989:
987:
984:
982:
979:
977:
976:Levoverbenone
974:
971:
967:
964:
962:
959:
956:
952:
948:
944:
941:
939:
936:
934:
931:
929:
926:
924:
921:
919:
916:
914:
911:
910:
908:
906:
902:
897:
893:
886:
881:
879:
874:
872:
867:
866:
863:
853:
849:
843:
840:
835:
831:
827:
823:
820:(7): 446–58.
819:
815:
808:
805:
799:
797:
795:
791:
787:
779:
774:
771:
768:
767:
763:
761:
755:
753:
747:
745:
739:
737:
731:
729:
727:
719:
717:
715:
711:
707:
703:
695:
693:
691:
687:
683:
675:
671:
667:
665:
661:
657:
653:
650:
647:
643:
640:
637:
634:
631:
628:
625:
624:
623:
621:
617:
613:
609:
601:
599:
597:
593:
592:heart disease
589:
585:
581:
577:
573:
569:
565:
561:
557:
553:
549:
545:
535:
528:
522:
513:
508:
504:
497:
488:
484:
477:
470:
466:
465:
463:
460:
455:
448:
446:
442:
418:
416:
412:
407:
403:
399:
396:
394:
392:ECHA InfoCard
388:
380:
376:
375:DTXSID0048343
372:
371:
369:
360:
356:
349:
348:ChEMBL1500276
345:
344:
342:
340:
336:
329:
325:
324:
322:
320:
316:
309:
305:
304:
302:
300:
296:
289:
285:
284:
282:
280:
276:
269:
265:
264:
262:
260:
256:
249:
245:
244:
242:
235:
231:
224:
220:
219:
217:
215:
211:
202:
198:
191:
186:
178:
173:
170:
169:
167:
165:
161:
157:
153:
151:
147:
143:
140:Clinical data
138:
134:
129:
121:
113:
110:
102:
91:
88:
84:
81:
77:
74:
70:
67:
63:
60: –
59:
55:
54:Find sources:
48:
44:
38:
37:
32:This article
30:
26:
21:
20:
1456:Antitussives
1358:
1304:Droxypropine
1299:Dropropizine
1279:Cloperastine
1249:Benproperine
1213:Normethadone
1172:+homatropine
1168:+guaifenesin
1133:+guaifenesin
1039:Dornase alfa
955:+oxomemazine
951:+hydrocodone
905:Expectorants
852:the original
842:
817:
813:
807:
783:
759:
751:
743:
735:
723:
699:
696:Side effects
679:
670:bronchoscopy
605:
580:constipation
564:side effects
543:
542:
531:
525:
120:
105:
96:
86:
79:
72:
65:
53:
41:Please help
36:verification
33:
1419:from market
1379:Piperidione
1344:Moguisteine
1254:Benzonatate
1244:Alloclamide
1203:Nicocodeine
1164:Hydrocodone
1124:Butorphanol
1069:Neltenexine
966:Ipecacuanha
943:Guaifenesin
913:Althea root
639:Psychogenic
622:secretion.
608:antitussive
602:Indications
452: g·mol
398:100.006.740
188:Identifiers
1450:Categories
1389:Tipepidine
1374:Pipazetate
1354:Nepinalone
1349:Morclofone
1339:Meprotixol
1329:Isoaminile
1319:Gefapixant
1274:Clofedanol
1269:Clobutinol
1264:Butamirate
1223:Pholcodine
1149:Dimemorfan
1100:alkaloids,
1054:Letosteine
1049:Erdosteine
1044:Eprazinone
1019:Bromhexine
1001:Mucolytics
800:References
660:bronchitis
656:tracheitis
652:Infectious
627:Irritative
618:and thins
556:dependence
457:3D model (
445:Molar mass
308:SNC1080T5Y
279:ChemSpider
214:CAS Number
197:IUPAC name
69:newspapers
58:"Oxeladin"
1429:Phase III
1417:Withdrawn
1364:Oxolamine
1314:Fominoben
1309:Fedrilate
1218:Noscapine
1198:Methadone
1079:Stepronin
991:Tyloxapol
720:Addiction
706:dizziness
692:therapy.
686:pregnancy
680:Although
664:pneumonia
620:bronchial
616:secretion
584:analgesia
576:tolerance
566:(such as
560:addiction
150:Drugs.com
99:July 2011
1394:Zipeprol
1359:Oxeladin
1324:Glaucine
1284:Dibunate
1228:Thebacon
1183:Laudanum
1074:Sobrerol
1059:Mannitol
1034:Domiodol
1014:Ambroxol
947:+codeine
933:Creosote
834:13439531
712:or mild
710:sedation
633:Allergic
568:hypnosis
544:Oxeladin
534:(verify)
259:DrugBank
223:468-61-1
164:ATC code
125:Oxeladin
1129:Codeine
1103:opioids
928:Cineole
790:Germany
786:Armenia
756:Tablets
726:codeine
654:cough:
588:codeine
450:335.488
415:Formula
268:DB04822
234:PubChem
180:)
174: (
172:R05DB09
83:scholar
1466:Ethers
1412:WHO-EM
1159:Heroin
986:Senega
832:
764:Dosage
596:bulbar
483:SMILES
339:ChEMBL
328:D08310
85:
78:
71:
64:
56:
1237:Other
1098:Opium
1064:Mesna
748:Syrup
740:Drops
641:cough
635:cough
629:cough
552:opium
546:is a
503:InChI
459:JSmol
90:JSTOR
76:books
830:PMID
702:rash
690:MAOI
582:and
319:KEGG
299:UNII
288:4458
248:4619
146:AHFS
62:news
896:R05
822:doi
558:or
364:EPA
238:CID
177:WHO
45:by
1452::
1425::
1170:,
953:,
949:,
828:.
816:.
708:,
704:,
662:,
658:,
578:,
574:,
570:,
429:33
423:20
1174:)
1166:(
1135:)
1131:(
1105:,
972:)
968:(
957:)
945:(
898:)
894:(
884:e
877:t
870:v
836:.
824::
818:9
648:)
461:)
438:3
435:O
432:N
426:H
420:C
366:)
362:(
148:/
112:)
106:(
101:)
97:(
87:·
80:·
73:·
66:·
39:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
