Knowledge

Auer rod

Source đź“ť

121: 145: 136: 120: 395: 209: 358: 20: 364: 388: 105:, as Auer himself acknowledged in his 1906 paper. Both McCrae and Auer mistakenly thought that the cells containing the rods were 309: 669: 381: 59: 207:
Auer, John (1906). "Some hitherto undescribed structures found in the large lymphocytes of a case of acute leukaemia".
70: 706: 694: 531: 477: 98: 66: 731: 144: 726: 489: 787: 258: 628: 167: 135: 102: 55: 580: 741: 585: 736: 664: 590: 521: 554: 368: 234: 349: 782: 721: 716: 328: 285: 226: 189: 647: 569: 318: 275: 267: 218: 179: 44: 85:
and can resemble needles, commas, diamonds, rectangles, corkscrews, or (rarely) granules.
19: 711: 674: 454: 413: 280: 253: 127: 63: 51: 776: 559: 484: 222: 238: 699: 549: 438: 433: 428: 686: 595: 508: 472: 462: 404: 353: 106: 38: 184: 656: 623: 605: 503: 126:
Bone marrow aspirate showing acute myeloid leukemia with Auer rods in several
78: 23: 230: 513: 498: 168:"Microscopic and Histochemical Studies on the Auer Bodies in Leukemic Cells" 94: 82: 74: 41: 332: 289: 271: 193: 633: 467: 48: 373: 323: 304: 18: 377: 97:, they were first described in 1905 by Canadian physician 254:"Acute lymphatic leukaemia with a report of five cases" 93:
Although Auer rods are named for American physiologist
750: 685: 655: 646: 616: 568: 542: 447: 421: 412: 26:with an Auer rod (to the left of the nucleus). 389: 8: 652: 418: 396: 382: 374: 322: 279: 183: 210:American Journal of the Medical Sciences 16:Crystalline cytoplasmic inclusion bodies 158: 116: 7: 14: 252:McCrae, Thomas (February 1905). 223:10.1097/00000441-190606000-00008 143: 134: 119: 310:American Journal of Hematology 1: 303:Bain, Barbara (August 2011). 166:Ackerman, G. Adolph (1950). 71:myeloproliferative disorders 60:acute promyelocytic leukemia 305:"Auer rods or McCrae rods?" 804: 185:10.1182/blood.V5.9.847.847 695:Hypersegmented neutrophil 602:Hemoglobin precipitation 532:Hereditary stomatocytosis 478:Hereditary elliptocytosis 67:myelodysplastic syndromes 727:Critical green inclusion 518:Sickle cell/drepanocyte 490:Hereditary spherocytosis 459:Membrane abnormalities 259:British Medical Journal 629:Red cell agglutination 272:10.1136/bmj.1.2304.404 103:Johns Hopkins Hospital 56:acute myeloid leukemia 47:sometimes observed in 27: 73:. Composed of fused 22: 732:Alder–Reilly anomaly 586:Basophilic stippling 707:Pelger–HuĂ«t anomaly 665:Reactive lymphocyte 591:Pappenheimer bodies 522:Sickle cell disease 555:Hypochromic anemia 369:University of Utah 28: 770: 769: 766: 765: 722:Toxic vacuolation 717:Toxic granulation 648:White blood cells 642: 641: 581:Howell–Jolly body 324:10.1002/ajh.21978 266:(2304): 404–408. 113:Additional images 79:lysosomal enzymes 795: 737:Jordans' anomaly 653: 570:Inclusion bodies 419: 398: 391: 384: 375: 361:at wadsworth.org 337: 336: 326: 300: 294: 293: 283: 249: 243: 242: 217:(6): 1002–1015. 204: 198: 197: 187: 163: 147: 138: 123: 81:, Auer rods are 45:inclusion bodies 803: 802: 798: 797: 796: 794: 793: 792: 773: 772: 771: 762: 746: 681: 638: 612: 564: 538: 443: 414:Red blood cells 408: 402: 346: 341: 340: 302: 301: 297: 251: 250: 246: 206: 205: 201: 165: 164: 160: 155: 148: 139: 130: 124: 115: 91: 17: 12: 11: 5: 801: 799: 791: 790: 788:Histopathology 785: 775: 774: 768: 767: 764: 763: 761: 760: 754: 752: 748: 747: 745: 744: 739: 734: 729: 724: 719: 714: 709: 704: 703: 702: 691: 689: 683: 682: 680: 679: 678: 677: 675:Russell bodies 667: 661: 659: 650: 644: 643: 640: 639: 637: 636: 631: 626: 620: 618: 614: 613: 611: 610: 609: 608: 600: 599: 598: 593: 588: 583: 577:Developmental 574: 572: 566: 565: 563: 562: 557: 552: 546: 544: 540: 539: 537: 536: 535: 534: 526: 525: 524: 516: 511: 506: 501: 496: 495: 494: 493: 492: 482: 481: 480: 470: 465: 457: 455:Poikilocytosis 451: 449: 445: 444: 442: 441: 436: 431: 425: 423: 416: 410: 409: 403: 401: 400: 393: 386: 378: 372: 371: 362: 356: 345: 344:External links 342: 339: 338: 295: 244: 199: 178:(9): 847–863. 157: 156: 154: 151: 150: 149: 142: 140: 133: 131: 125: 118: 114: 111: 90: 87: 15: 13: 10: 9: 6: 4: 3: 2: 800: 789: 786: 784: 781: 780: 778: 759: 756: 755: 753: 749: 743: 740: 738: 735: 733: 730: 728: 725: 723: 720: 718: 715: 713: 710: 708: 705: 701: 698: 697: 696: 693: 692: 690: 688: 684: 676: 673: 672: 671: 668: 666: 663: 662: 660: 658: 654: 651: 649: 645: 635: 632: 630: 627: 625: 622: 621: 619: 615: 607: 604: 603: 601: 597: 594: 592: 589: 587: 584: 582: 579: 578: 576: 575: 573: 571: 567: 561: 560:Polychromasia 558: 556: 553: 551: 548: 547: 545: 541: 533: 530: 529: 527: 523: 520: 519: 517: 515: 512: 510: 507: 505: 502: 500: 497: 491: 488: 487: 486: 483: 479: 476: 475: 474: 471: 469: 466: 464: 461: 460: 458: 456: 453: 452: 450: 446: 440: 437: 435: 432: 430: 427: 426: 424: 420: 417: 415: 411: 406: 399: 394: 392: 387: 385: 380: 379: 376: 370: 366: 363: 360: 357: 355: 351: 348: 347: 343: 334: 330: 325: 320: 316: 312: 311: 306: 299: 296: 291: 287: 282: 277: 273: 269: 265: 261: 260: 255: 248: 245: 240: 236: 232: 228: 224: 220: 216: 212: 211: 203: 200: 195: 191: 186: 181: 177: 173: 169: 162: 159: 152: 146: 141: 137: 132: 129: 122: 117: 112: 110: 108: 104: 100: 99:Thomas McCrae 96: 88: 86: 84: 80: 76: 72: 68: 65: 61: 57: 54:cells during 53: 50: 46: 43: 40: 37:) are large, 36: 32: 25: 21: 757: 712:Döhle bodies 700:Arneth count 687:Granulocytes 550:Anisochromia 528:Stomatocyte 439:Microcytosis 434:Macrocytosis 429:Anisocytosis 314: 308: 298: 263: 257: 247: 214: 208: 202: 175: 171: 161: 107:lymphoblasts 92: 77:and rich in 34: 30: 29: 670:Smudge cell 657:Lymphocytes 596:Cabot rings 509:Schistocyte 473:Elliptocyte 463:Acanthocyte 354:MedlinePlus 83:azurophilic 42:cytoplasmic 39:crystalline 35:Auer bodies 777:Categories 742:Left shift 624:Haemoconia 606:Heinz body 504:Echinocyte 485:Spherocyte 405:Blood film 317:(8): 689. 153:References 101:, then at 64:high-grade 24:Myeloblast 514:Degmacyte 499:Dacrocyte 231:0002-9629 95:John Auer 75:lysosomes 31:Auer rods 783:Leukemia 758:Auer rod 634:Rouleaux 468:Codocyte 407:findings 333:21761434 290:20761949 239:71853154 194:15434012 352:at NIH/ 281:2319598 49:myeloid 543:Colour 359:Slides 331:  288:  278:  237:  229:  192:  128:blasts 89:Eponym 751:Other 617:Other 448:Shape 365:Image 350:Image 235:S2CID 172:Blood 52:blast 422:Size 329:PMID 286:PMID 227:ISSN 190:PMID 69:and 33:(or 367:at 319:doi 276:PMC 268:doi 219:doi 215:131 180:doi 779:: 327:. 315:86 313:. 307:. 284:. 274:. 262:. 256:. 233:. 225:. 213:. 188:. 174:. 170:. 109:. 62:, 58:, 397:e 390:t 383:v 335:. 321:: 292:. 270:: 264:1 241:. 221:: 196:. 182:: 176:5

Index


Myeloblast
crystalline
cytoplasmic
inclusion bodies
myeloid
blast
acute myeloid leukemia
acute promyelocytic leukemia
high-grade
myelodysplastic syndromes
myeloproliferative disorders
lysosomes
lysosomal enzymes
azurophilic
John Auer
Thomas McCrae
Johns Hopkins Hospital
lymphoblasts
Bone marrow aspirate showing acute myeloid leukemia with Auer rods in several blasts
blasts


"Microscopic and Histochemical Studies on the Auer Bodies in Leukemic Cells"
doi
10.1182/blood.V5.9.847.847
PMID
15434012
American Journal of the Medical Sciences
doi

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.

↑