Knowledge (XXG)

ADAM22

Source đź“ť

308: 285: 182: 207: 573: 566: 559: 314: 213: 2646: 2666: 61: 1722:
D'Abaco GM, Ng K, Paradiso L, Godde NJ, Kaye A, Novak U (January 2006). "ADAM22, expressed in normal brain but not in high-grade gliomas, inhibits cellular proliferation via the disintegrin domain".
1693:
Zhu P, Sang Y, Xu H, Zhao J, Xu R, Sun Y, Xu T, Wang X, Chen L, Feng H, Li C, Zhao S (June 2005). "ADAM22 plays an important role in cell adhesion and spreading with the assistance of 14-3-3".
1839:
Chabrol E, Gourfinkel-An I, Scheffer IE, Picard F, Couarch P, Berkovic SF, McMahon JM, Bajaj N, Mota-Vieira L, Mota R, Trouillard O, Depienne C, Baulac M, LeGuern E, Baulac S (August 2007).
1574:
Zhu Pc, Sun Y, Xu R, Sang Y, Zhao J, Liu G, Cai L, Li C, Zhao S (February 2003). "The interaction between ADAM 22 and 14-3-3zeta: regulation of cell adhesion and spreading".
1423:
Poindexter K, Nelson N, DuBose RF, Black RA, Cerretti DP (September 1999). "The identification of seven metalloproteinase-disintegrin (ADAM) genes from genomic libraries".
1794:
Fukata Y, Adesnik H, Iwanaga T, Bredt DS, Nicoll RA, Fukata M (September 2006). "Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission".
1475:
Fukata Y, Adesnik H, Iwanaga T, Bredt DS, Nicoll RA, Fukata M (September 2006). "Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission".
321: 220: 1533:"The specific expression of three novel splice variant forms of human metalloprotease-like disintegrin-like cysteine-rich protein 2 gene inBrain tissues and gliomas" 1970: 811: 792: 143: 1380:"Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain" 2750: 2711: 2312: 1360: 1342: 2730: 58: 1999: 1963: 1233: 1930: 307: 1147: 2365: 284: 1461: 1154: 1329: 1308: 1956: 1761:"Efficient ADAM22 surface expression is mediated by phosphorylation-dependent interaction with 14-3-3 protein family members" 2521: 1936: 1325: 1255:, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including 206: 181: 2636: 1304: 1251:
etalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom
2317: 123: 1276: 320: 219: 1840: 2211: 2206: 313: 212: 2506: 2704: 2622: 2609: 2596: 2583: 2570: 2557: 2544: 1990: 2516: 2470: 2413: 2327: 2144: 1987: 856: 131: 1648:
Sagane K, Hayakawa K, Kai J, Hirohashi T, Takahashi E, Miyamoto N, Ino M, Oki T, Yamazaki K, Nagasu T (2006).
2740: 2418: 1883:
Gödde NJ, D'Abaco GM, Paradiso L, Novak U (November 2007). "Differential coding potential of ADAM22 mRNAs".
837: 2439: 2358: 2302: 2511: 1841:"Absence of mutations in the LGI1 receptor ADAM22 gene in autosomal dominant lateral temporal epilepsy" 2697: 1983: 1803: 1484: 195: 2475: 1942: 1130: 1126: 1122: 1118: 1114: 1067: 1063: 1059: 1055: 1051: 1031: 1027: 1023: 1019: 1015: 994: 990: 986: 982: 978: 974: 970: 966: 962: 958: 954: 950: 946: 110: 2745: 2735: 2408: 1871: 1827: 1747: 1508: 155: 1093: 1089: 1085: 1081: 1077: 936: 932: 928: 924: 920: 1948: 1531:
Harada T, Nishie A, Torigoe K, Ikezaki K, Shono T, Maehara Y, Kuwano M, Wada M (October 2000).
572: 565: 558: 1900: 1863: 1819: 1782: 1739: 1710: 1681: 1636: 1591: 1562: 1500: 1440: 1405: 103: 51: 2681: 2454: 2449: 2423: 2351: 2251: 1892: 1855: 1811: 1772: 1731: 1702: 1671: 1661: 1626: 1616: 1583: 1552: 1544: 1492: 1432: 1395: 1387: 400: 331: 275: 230: 151: 1924: 2501: 2485: 2398: 2007: 375: 1807: 1488: 2650: 2539: 2480: 1735: 1676: 1649: 1557: 1548: 1532: 1400: 1379: 1631: 1604: 1587: 1436: 726: 721: 716: 711: 706: 701: 696: 691: 675: 670: 665: 660: 655: 650: 645: 629: 624: 619: 614: 2724: 2444: 2403: 1859: 1256: 601: 1875: 1831: 1751: 1512: 135: 2677: 2393: 1260: 393: 172: 1267:
ligand in the brain. Alternative splicing results in several transcript variants.
159: 2617: 2552: 2388: 2322: 2307: 2152: 1365:
National Center for Biotechnology Information, U.S. National Library of Medicine
1347:
National Center for Biotechnology Information, U.S. National Library of Medicine
1252: 2645: 1896: 1706: 476: 2297: 2169: 292: 189: 139: 2591: 2565: 1815: 1496: 756: 536: 414: 359: 346: 258: 245: 147: 1904: 1867: 1823: 1786: 1743: 1714: 1685: 1666: 1640: 1621: 1595: 1566: 1504: 1444: 1409: 1194: 1189: 2332: 2134: 2129: 2124: 1979: 1264: 1178: 901: 882: 2119: 2114: 2109: 2104: 2099: 2094: 2089: 868: 823: 1777: 1760: 1650:"Ataxia and peripheral nerve hypomyelination in ADAM22-deficient mice" 1391: 80: 2604: 2374: 2256: 2084: 2079: 2074: 2064: 2059: 2054: 2049: 2027: 2022: 2017: 1920: 1214: 1162: 778: 24: 2665: 1263:. This gene is highly expressed in the brain and may function as an 2578: 2281: 2276: 2271: 2266: 2261: 2246: 2241: 2236: 2231: 2226: 2221: 2216: 2201: 2196: 2044: 2039: 2034: 2012: 741: 737: 2673: 2191: 2186: 2179: 2174: 2162: 2157: 1280: 1221: 581: 127: 2347: 1952: 114:, ADAM 22, MDC2, ADAM metallopeptidase domain 22, EIEE61, DEE61 1207:
Disintegrin and metalloproteinase domain-containing protein 22
2343: 1759:
Gödde NJ, D'Abaco GM, Paradiso L, Novak U (August 2006).
383: 2685: 1378:
Sagane K, Ohya Y, Hasegawa Y, Tanaka I (August 1998).
2634: 1923:
online database for peptidases and their inhibitors:
1462:"Entrez Gene: ADAM22 ADAM metallopeptidase domain 22" 548: 2530: 2494: 2463: 2432: 2381: 2290: 2143: 1998: 1695:
Biochemical and Biophysical Research Communications
1576:
Biochemical and Biophysical Research Communications
1107: 1050: 1008: 919: 676:
integral component of postsynaptic density membrane
1321: 1319: 1317: 1300: 1298: 1296: 330: 229: 1326:GRCm38: Ensembl release 89: ENSMUSG00000040537 2705: 2359: 1964: 8: 1605:"An unappreciated role for RNA surveillance" 1305:GRCh38: Ensembl release 89: ENSG00000008277 2712: 2698: 2366: 2352: 2344: 1971: 1957: 1949: 1047: 916: 752: 597: 371: 270: 167: 69: 1776: 1675: 1665: 1630: 1620: 1603:Hillman RT, Green RE, Brenner SE (2005). 1556: 1399: 1456: 1454: 717:myelination in peripheral nervous system 2641: 1292: 29: 2313:Pregnancy-associated plasma protein A 335: 296: 291: 234: 193: 188: 7: 2662: 2660: 702:negative regulation of cell adhesion 1537:Japanese Journal of Cancer Research 2684:. You can help Knowledge (XXG) by 1736:10.1227/01.NEU.0000192363.84287.8B 1549:10.1111/j.1349-7006.2000.tb00877.x 1104: 1005: 892: 873: 847: 828: 802: 783: 707:central nervous system development 553: 471: 409: 388: 14: 1217:that in humans is encoded by the 425:lateral nuclear group of thalamus 19:This article is about the enzyme 2664: 2644: 1860:10.1016/j.eplepsyres.2007.06.014 1730:(1): 179–86, discussion 179–86. 571: 564: 557: 519:dorsomedial hypothalamic nucleus 319: 312: 306: 283: 218: 211: 205: 180: 646:integral component of membrane 582:More reference expression data 537:More reference expression data 1: 2751:Human chromosome 7 gene stubs 1588:10.1016/S0006-291X(03)00056-1 1437:10.1016/S0378-1119(99)00302-9 620:metalloendopeptidase activity 304: 203: 2318:Bone morphogenetic protein 1 1386:. 334 ( Pt 1) (Pt 1): 93–8. 692:Schwann cell differentiation 23:. For the podcast host, see 2731:Genes on human chromosome 7 2767: 2659: 1941:gene details page in the 1897:10.1016/j.gene.2007.07.033 1707:10.1016/j.bbrc.2005.03.229 1259:, muscle development, and 1232:ADAM22 is a member of the 18: 2522:Michaelis–Menten kinetics 2145:Matrix metalloproteinases 1361:"Mouse PubMed Reference:" 1343:"Human PubMed Reference:" 1275:ADAM22 has been shown to 1193: 1188: 1184: 1177: 1161: 1142: 1111: 1074: 1043: 1012: 943: 912: 899: 895: 880: 876: 867: 854: 850: 835: 831: 822: 809: 805: 790: 786: 777: 762: 755: 751: 735: 697:adult locomotory behavior 630:metallopeptidase activity 600: 596: 579: 556: 547: 534: 511:medial geniculate nucleus 483: 474: 421: 412: 382: 374: 370: 353: 340: 303: 282: 273: 269: 252: 239: 202: 179: 170: 166: 121: 118: 108: 101: 96: 77: 72: 55: 50: 45: 41: 37: 32: 2414:Diffusion-limited enzyme 2328:Insulin-degrading enzyme 507:anterior amygdaloid area 1816:10.1126/science.1129947 1765:Journal of Cell Science 1497:10.1126/science.1129947 1384:The Biochemical Journal 1667:10.1186/1471-2202-6-33 1622:10.1186/gb-2004-5-2-r8 1148:Chr 7: 87.93 – 88.2 Mb 499:lateral septal nucleus 461:superior frontal gyrus 16:Enzyme found in humans 2507:Eadie–Hofstee diagram 2440:Allosteric regulation 2303:Procollagen peptidase 1984:metalloendopeptidases 1155:Chr 5: 8.12 – 8.42 Mb 671:glutamatergic synapse 457:cerebellar hemisphere 429:middle temporal gyrus 2517:Lineweaver–Burk plot 1935:genome location and 523:ventromedial nucleus 445:orbitofrontal cortex 298:Chromosome 5 (mouse) 196:Chromosome 7 (human) 73:List of PDB id codes 46:Available structures 1943:UCSC Genome Browser 1808:2006Sci...313.1792F 1771:(Pt 16): 3296–305. 1489:2006Sci...313.1792F 337:5 A1|5 3.39 cM 2672:This article on a 2476:Enzyme superfamily 2409:Enzyme promiscuity 857:ENSMUSG00000040537 685:Biological process 639:Cellular component 608:Molecular function 487:lobe of cerebellum 160:ADAM22 - orthologs 2693: 2692: 2632: 2631: 2341: 2340: 1848:Epilepsy Research 1778:10.1242/jcs.03065 1392:10.1042/bj3340093 1204: 1203: 1200: 1199: 1173: 1172: 1138: 1137: 1101: 1100: 1039: 1038: 1002: 1001: 908: 907: 889: 888: 863: 862: 844: 843: 818: 817: 799: 798: 747: 746: 592: 591: 588: 587: 543: 542: 530: 529: 515:nucleus accumbens 491:cerebellar vermis 468: 467: 441:postcentral gyrus 366: 365: 265: 264: 92: 91: 88: 87: 56:Ortholog search: 2758: 2714: 2707: 2700: 2668: 2661: 2649: 2648: 2640: 2512:Hanes–Woolf plot 2455:Enzyme activator 2450:Enzyme inhibitor 2424:Enzyme catalysis 2368: 2361: 2354: 2345: 2008:Alpha secretases 1973: 1966: 1959: 1950: 1908: 1879: 1845: 1835: 1802:(5794): 1792–5. 1790: 1780: 1755: 1718: 1689: 1679: 1669: 1654:BMC Neuroscience 1644: 1634: 1624: 1599: 1570: 1560: 1517: 1516: 1483:(5794): 1792–5. 1472: 1466: 1465: 1458: 1449: 1448: 1420: 1414: 1413: 1403: 1375: 1369: 1368: 1357: 1351: 1350: 1339: 1333: 1323: 1312: 1302: 1209:, also known as 1186: 1185: 1157: 1150: 1133: 1105: 1096: 1048: 1044:RefSeq (protein) 1034: 1006: 997: 917: 893: 874: 848: 829: 803: 784: 753: 615:integrin binding 598: 584: 575: 568: 561: 554: 539: 479: 477:Top expressed in 472: 449:Brodmann area 46 437:Brodmann area 23 417: 415:Top expressed in 410: 389: 372: 362: 349: 338: 323: 316: 310: 299: 287: 271: 261: 248: 237: 222: 215: 209: 198: 184: 168: 162: 113: 106: 83: 70: 64: 43: 42: 30: 2766: 2765: 2761: 2760: 2759: 2757: 2756: 2755: 2721: 2720: 2719: 2718: 2657: 2655: 2643: 2635: 2633: 2628: 2540:Oxidoreductases 2526: 2502:Enzyme kinetics 2490: 2486:List of enzymes 2459: 2428: 2399:Catalytic triad 2377: 2372: 2342: 2337: 2286: 2139: 1994: 1977: 1916: 1911: 1882: 1843: 1838: 1793: 1758: 1721: 1692: 1647: 1602: 1573: 1530: 1526: 1524:Further reading 1521: 1520: 1474: 1473: 1469: 1460: 1459: 1452: 1422: 1421: 1417: 1377: 1376: 1372: 1359: 1358: 1354: 1341: 1340: 1336: 1324: 1315: 1303: 1294: 1289: 1273: 1230: 1195:View/Edit Mouse 1190:View/Edit Human 1153: 1146: 1143:Location (UCSC) 1129: 1125: 1121: 1117: 1113: 1092: 1088: 1084: 1080: 1076: 1070: 1066: 1062: 1058: 1054: 1030: 1026: 1022: 1018: 1014: 993: 989: 985: 981: 977: 973: 969: 965: 961: 957: 953: 949: 945: 939: 935: 931: 927: 923: 838:ENSG00000008277 731: 680: 661:cell projection 656:plasma membrane 634: 625:protein binding 580: 570: 569: 563: 562: 535: 526: 521: 517: 513: 509: 505: 501: 497: 495:dorsal striatum 493: 489: 475: 464: 459: 455: 451: 447: 443: 439: 435: 431: 427: 413: 357: 344: 336: 326: 325: 324: 317: 297: 274:Gene location ( 256: 243: 235: 225: 224: 223: 216: 194: 171:Gene location ( 122: 109: 102: 79: 57: 28: 17: 12: 11: 5: 2764: 2762: 2754: 2753: 2748: 2743: 2741:Human proteins 2738: 2733: 2723: 2722: 2717: 2716: 2709: 2702: 2694: 2691: 2690: 2669: 2654: 2653: 2630: 2629: 2627: 2626: 2613: 2600: 2587: 2574: 2561: 2548: 2534: 2532: 2528: 2527: 2525: 2524: 2519: 2514: 2509: 2504: 2498: 2496: 2492: 2491: 2489: 2488: 2483: 2478: 2473: 2467: 2465: 2464:Classification 2461: 2460: 2458: 2457: 2452: 2447: 2442: 2436: 2434: 2430: 2429: 2427: 2426: 2421: 2416: 2411: 2406: 2401: 2396: 2391: 2385: 2383: 2379: 2378: 2373: 2371: 2370: 2363: 2356: 2348: 2339: 2338: 2336: 2335: 2330: 2325: 2320: 2315: 2310: 2305: 2300: 2294: 2292: 2288: 2287: 2285: 2284: 2279: 2274: 2269: 2264: 2259: 2254: 2249: 2244: 2239: 2234: 2229: 2224: 2219: 2214: 2209: 2204: 2199: 2194: 2189: 2184: 2183: 2182: 2177: 2167: 2166: 2165: 2160: 2149: 2147: 2141: 2140: 2138: 2137: 2132: 2127: 2122: 2117: 2112: 2107: 2102: 2097: 2092: 2087: 2082: 2077: 2072: 2067: 2062: 2057: 2052: 2047: 2042: 2037: 2032: 2031: 2030: 2025: 2020: 2015: 2004: 2002: 1996: 1995: 1978: 1976: 1975: 1968: 1961: 1953: 1947: 1946: 1927: 1915: 1914:External links 1912: 1910: 1909: 1880: 1836: 1791: 1756: 1719: 1690: 1645: 1609:Genome Biology 1600: 1571: 1543:(10): 1001–6. 1527: 1525: 1522: 1519: 1518: 1467: 1450: 1415: 1370: 1352: 1334: 1313: 1291: 1290: 1288: 1285: 1272: 1269: 1229: 1226: 1202: 1201: 1198: 1197: 1192: 1182: 1181: 1175: 1174: 1171: 1170: 1168: 1166: 1159: 1158: 1151: 1144: 1140: 1139: 1136: 1135: 1109: 1108: 1102: 1099: 1098: 1072: 1071: 1045: 1041: 1040: 1037: 1036: 1010: 1009: 1003: 1000: 999: 941: 940: 914: 910: 909: 906: 905: 897: 896: 890: 887: 886: 878: 877: 871: 865: 864: 861: 860: 852: 851: 845: 842: 841: 833: 832: 826: 820: 819: 816: 815: 807: 806: 800: 797: 796: 788: 787: 781: 775: 774: 769: 764: 760: 759: 749: 748: 745: 744: 733: 732: 730: 729: 724: 719: 714: 709: 704: 699: 694: 688: 686: 682: 681: 679: 678: 673: 668: 663: 658: 653: 648: 642: 640: 636: 635: 633: 632: 627: 622: 617: 611: 609: 605: 604: 594: 593: 590: 589: 586: 585: 577: 576: 551: 545: 544: 541: 540: 532: 531: 528: 527: 525: 524: 520: 516: 512: 508: 504: 500: 496: 492: 488: 484: 481: 480: 469: 466: 465: 463: 462: 458: 454: 450: 446: 442: 438: 434: 430: 426: 422: 419: 418: 406: 405: 397: 386: 380: 379: 376:RNA expression 368: 367: 364: 363: 355: 351: 350: 342: 339: 334: 328: 327: 318: 311: 305: 301: 300: 295: 289: 288: 280: 279: 267: 266: 263: 262: 254: 250: 249: 241: 238: 233: 227: 226: 217: 210: 204: 200: 199: 192: 186: 185: 177: 176: 164: 163: 120: 116: 115: 107: 99: 98: 94: 93: 90: 89: 86: 85: 75: 74: 66: 65: 54: 48: 47: 39: 38: 35: 34: 15: 13: 10: 9: 6: 4: 3: 2: 2763: 2752: 2749: 2747: 2744: 2742: 2739: 2737: 2734: 2732: 2729: 2728: 2726: 2715: 2710: 2708: 2703: 2701: 2696: 2695: 2689: 2687: 2683: 2679: 2675: 2670: 2667: 2663: 2658: 2652: 2647: 2642: 2638: 2624: 2620: 2619: 2614: 2611: 2607: 2606: 2601: 2598: 2594: 2593: 2588: 2585: 2581: 2580: 2575: 2572: 2568: 2567: 2562: 2559: 2555: 2554: 2549: 2546: 2542: 2541: 2536: 2535: 2533: 2529: 2523: 2520: 2518: 2515: 2513: 2510: 2508: 2505: 2503: 2500: 2499: 2497: 2493: 2487: 2484: 2482: 2481:Enzyme family 2479: 2477: 2474: 2472: 2469: 2468: 2466: 2462: 2456: 2453: 2451: 2448: 2446: 2445:Cooperativity 2443: 2441: 2438: 2437: 2435: 2431: 2425: 2422: 2420: 2417: 2415: 2412: 2410: 2407: 2405: 2404:Oxyanion hole 2402: 2400: 2397: 2395: 2392: 2390: 2387: 2386: 2384: 2380: 2376: 2369: 2364: 2362: 2357: 2355: 2350: 2349: 2346: 2334: 2331: 2329: 2326: 2324: 2321: 2319: 2316: 2314: 2311: 2309: 2306: 2304: 2301: 2299: 2296: 2295: 2293: 2289: 2283: 2280: 2278: 2275: 2273: 2270: 2268: 2265: 2263: 2260: 2258: 2255: 2253: 2250: 2248: 2245: 2243: 2240: 2238: 2235: 2233: 2230: 2228: 2225: 2223: 2220: 2218: 2215: 2213: 2210: 2208: 2205: 2203: 2200: 2198: 2195: 2193: 2190: 2188: 2185: 2181: 2178: 2176: 2173: 2172: 2171: 2168: 2164: 2161: 2159: 2156: 2155: 2154: 2151: 2150: 2148: 2146: 2142: 2136: 2133: 2131: 2128: 2126: 2123: 2121: 2118: 2116: 2113: 2111: 2108: 2106: 2103: 2101: 2098: 2096: 2093: 2091: 2088: 2086: 2083: 2081: 2078: 2076: 2073: 2071: 2068: 2066: 2063: 2061: 2058: 2056: 2053: 2051: 2048: 2046: 2043: 2041: 2038: 2036: 2033: 2029: 2026: 2024: 2021: 2019: 2016: 2014: 2011: 2010: 2009: 2006: 2005: 2003: 2001: 2000:ADAM proteins 1997: 1992: 1989: 1985: 1981: 1974: 1969: 1967: 1962: 1960: 1955: 1954: 1951: 1944: 1940: 1939: 1934: 1933: 1928: 1926: 1922: 1918: 1917: 1913: 1906: 1902: 1898: 1894: 1891:(1–2): 80–8. 1890: 1886: 1881: 1877: 1873: 1869: 1865: 1861: 1857: 1853: 1849: 1842: 1837: 1833: 1829: 1825: 1821: 1817: 1813: 1809: 1805: 1801: 1797: 1792: 1788: 1784: 1779: 1774: 1770: 1766: 1762: 1757: 1753: 1749: 1745: 1741: 1737: 1733: 1729: 1725: 1720: 1716: 1712: 1708: 1704: 1701:(4): 938–46. 1700: 1696: 1691: 1687: 1683: 1678: 1673: 1668: 1663: 1659: 1655: 1651: 1646: 1642: 1638: 1633: 1628: 1623: 1618: 1614: 1610: 1606: 1601: 1597: 1593: 1589: 1585: 1581: 1577: 1572: 1568: 1564: 1559: 1554: 1550: 1546: 1542: 1538: 1534: 1529: 1528: 1523: 1514: 1510: 1506: 1502: 1498: 1494: 1490: 1486: 1482: 1478: 1471: 1468: 1463: 1457: 1455: 1451: 1446: 1442: 1438: 1434: 1430: 1426: 1419: 1416: 1411: 1407: 1402: 1397: 1393: 1389: 1385: 1381: 1374: 1371: 1366: 1362: 1356: 1353: 1348: 1344: 1338: 1335: 1331: 1327: 1322: 1320: 1318: 1314: 1310: 1306: 1301: 1299: 1297: 1293: 1286: 1284: 1282: 1278: 1270: 1268: 1266: 1262: 1258: 1257:fertilization 1254: 1250: 1246: 1242: 1239: 1235: 1227: 1225: 1223: 1220: 1216: 1212: 1208: 1196: 1191: 1187: 1183: 1180: 1176: 1169: 1167: 1164: 1160: 1156: 1152: 1149: 1145: 1141: 1134: 1132: 1128: 1124: 1120: 1116: 1110: 1106: 1103: 1097: 1095: 1091: 1087: 1083: 1079: 1073: 1069: 1065: 1061: 1057: 1053: 1049: 1046: 1042: 1035: 1033: 1029: 1025: 1021: 1017: 1011: 1007: 1004: 998: 996: 992: 988: 984: 980: 976: 972: 968: 964: 960: 956: 952: 948: 942: 938: 934: 930: 926: 922: 918: 915: 913:RefSeq (mRNA) 911: 904: 903: 898: 894: 891: 885: 884: 879: 875: 872: 870: 866: 859: 858: 853: 849: 846: 840: 839: 834: 830: 827: 825: 821: 814: 813: 808: 804: 801: 795: 794: 789: 785: 782: 780: 776: 773: 770: 768: 765: 761: 758: 754: 750: 743: 739: 734: 728: 725: 723: 720: 718: 715: 713: 712:cell adhesion 710: 708: 705: 703: 700: 698: 695: 693: 690: 689: 687: 684: 683: 677: 674: 672: 669: 667: 664: 662: 659: 657: 654: 652: 649: 647: 644: 643: 641: 638: 637: 631: 628: 626: 623: 621: 618: 616: 613: 612: 610: 607: 606: 603: 602:Gene ontology 599: 595: 583: 578: 574: 567: 560: 555: 552: 550: 546: 538: 533: 522: 518: 514: 510: 506: 502: 498: 494: 490: 486: 485: 482: 478: 473: 470: 460: 456: 452: 448: 444: 440: 436: 432: 428: 424: 423: 420: 416: 411: 408: 407: 404: 402: 398: 396: 395: 391: 390: 387: 385: 381: 377: 373: 369: 361: 356: 352: 348: 343: 333: 329: 322: 315: 309: 302: 294: 290: 286: 281: 277: 272: 268: 260: 255: 251: 247: 242: 232: 228: 221: 214: 208: 201: 197: 191: 187: 183: 178: 174: 169: 165: 161: 157: 153: 149: 145: 141: 137: 133: 129: 125: 117: 112: 105: 100: 95: 84: 82: 76: 71: 68: 67: 63: 60: 53: 49: 44: 40: 36: 31: 26: 22: 2686:expanding it 2678:chromosome 7 2671: 2656: 2618:Translocases 2615: 2602: 2589: 2576: 2563: 2553:Transferases 2550: 2537: 2394:Binding site 2153:Collagenases 2069: 1937: 1931: 1888: 1884: 1851: 1847: 1799: 1795: 1768: 1764: 1727: 1724:Neurosurgery 1723: 1698: 1694: 1657: 1653: 1612: 1608: 1582:(4): 991–9. 1579: 1575: 1540: 1536: 1480: 1476: 1470: 1431:(1): 61–70. 1428: 1424: 1418: 1383: 1373: 1364: 1355: 1346: 1337: 1274: 1271:Interactions 1261:neurogenesis 1253:disintegrins 1248: 1244: 1240: 1237: 1231: 1218: 1210: 1206: 1205: 1131:NP_001297369 1127:NP_001297368 1123:NP_001091695 1119:NP_001007222 1115:NP_001007221 1112: 1075: 1068:NP_001311350 1064:NP_001311349 1060:NP_001311348 1056:NP_001311347 1052:NP_001311346 1032:NM_001310440 1028:NM_001310439 1024:NM_001098225 1020:NM_001007221 1016:NM_001007220 1013: 995:NM_001391982 991:NM_001391981 987:NM_001391980 983:NM_001391979 979:NM_001391978 975:NM_001391977 971:NM_001391976 967:NM_001391975 963:NM_001324421 959:NM_001324420 955:NM_001324419 951:NM_001324418 947:NM_001324417 944: 900: 881: 855: 836: 810: 791: 771: 766: 399: 392: 119:External IDs 78: 20: 2389:Active site 2323:Lysostaphin 2308:Thermolysin 2170:Gelatinases 1854:(1): 41–8. 1243:isintegrin 727:gliogenesis 722:proteolysis 257:88,202,889 244:87,934,143 97:Identifiers 2725:Categories 2592:Isomerases 2566:Hydrolases 2433:Regulation 2298:Neprilysin 1332:, May 2017 1311:, May 2017 1287:References 453:cerebellum 403:(ortholog) 358:8,418,160 345:8,122,352 140:HomoloGene 2746:EC 3.4.24 2736:Proteases 2676:on human 2471:EC number 1980:Proteases 1615:(2): R8. 1094:NP_068369 1090:NP_068368 1086:NP_068367 1082:NP_057435 1078:NP_004185 937:NM_021723 933:NM_021722 929:NM_021721 925:NM_016351 921:NM_004194 757:Orthologs 503:subiculum 148:GeneCards 2495:Kinetics 2419:Cofactor 2382:Activity 2333:ZMPSTE24 2135:ADAMTS13 2130:ADAMTS12 2125:ADAMTS10 1905:17884303 1876:28172409 1868:17681454 1832:33024022 1824:16990550 1787:16868027 1752:24601244 1744:16385342 1715:15882968 1686:15876356 1641:14759258 1596:12589811 1567:11050470 1513:33024022 1505:16990550 1445:10524237 1328:– 1307:– 1277:interact 1265:integrin 1228:Function 1213:, is an 1179:Wikidata 736:Sources: 666:membrane 2651:Biology 2605:Ligases 2375:Enzymes 2120:ADAMTS9 2115:ADAMTS8 2110:ADAMTS5 2105:ADAMTS4 2100:ADAMTS3 2095:ADAMTS2 2090:ADAMTS1 1925:M12.978 1804:Bibcode 1796:Science 1677:1142324 1558:5926265 1485:Bibcode 1477:Science 1410:9693107 1401:1219666 1330:Ensembl 1309:Ensembl 869:UniProt 824:Ensembl 763:Species 742:QuickGO 378:pattern 236:7q21.12 136:1340046 104:Aliases 2637:Portal 2579:Lyases 2257:MMP23B 2252:MMP23A 2085:ADAM33 2080:ADAM28 2075:ADAM23 2070:ADAM22 2065:ADAM18 2060:ADAM15 2055:ADAM12 2050:ADAM11 2028:ADAM19 2023:ADAM17 2018:ADAM10 1991:3.4.24 1938:ADAM22 1932:ADAM22 1929:Human 1921:MEROPS 1903:  1874:  1866:  1830:  1822:  1785:  1750:  1742:  1713:  1684:  1674:  1660:: 33. 1639:  1632:395752 1629:  1594:  1565:  1555:  1511:  1503:  1443:  1408:  1398:  1219:ADAM22 1215:enzyme 1211:ADAM22 1165:search 1163:PubMed 902:Q9R1V6 883:Q9P0K1 779:Entrez 549:BioGPS 152:ADAM22 128:603709 111:ADAM22 33:ADAM22 25:Adam22 21:ADAM22 2680:is a 2531:Types 2291:Other 2282:MMP28 2277:MMP27 2272:MMP26 2267:MMP25 2262:MMP24 2247:MMP21 2242:MMP20 2237:MMP19 2232:MMP17 2227:MMP16 2222:MMP15 2217:MMP14 2212:MMP13 2207:MMP12 2202:MMP11 2197:MMP10 2045:ADAM8 2040:ADAM7 2035:ADAM2 2013:ADAM9 1872:S2CID 1844:(PDF) 1828:S2CID 1748:S2CID 1509:S2CID 1279:with 812:11496 793:53616 772:Mouse 767:Human 738:Amigo 401:Mouse 394:Human 341:Start 276:Mouse 240:Start 173:Human 144:37898 2682:stub 2674:gene 2623:list 2616:EC7 2610:list 2603:EC6 2597:list 2590:EC5 2584:list 2577:EC4 2571:list 2564:EC3 2558:list 2551:EC2 2545:list 2538:EC1 2192:MMP7 2187:MMP3 2180:MMP9 2175:MMP2 2163:MMP8 2158:MMP1 1919:The 1901:PMID 1885:Gene 1864:PMID 1820:PMID 1783:PMID 1740:PMID 1711:PMID 1682:PMID 1637:PMID 1592:PMID 1563:PMID 1501:PMID 1441:PMID 1425:Gene 1406:PMID 1281:DLG4 1234:ADAM 1222:gene 651:axon 433:pons 384:Bgee 332:Band 293:Chr. 231:Band 190:Chr. 124:OMIM 81:3G5C 62:RCSB 59:PDBe 1893:doi 1889:403 1856:doi 1812:doi 1800:313 1773:doi 1769:119 1732:doi 1703:doi 1699:331 1672:PMC 1662:doi 1627:PMC 1617:doi 1584:doi 1580:301 1553:PMC 1545:doi 1493:doi 1481:313 1433:doi 1429:237 1396:PMC 1388:doi 1247:nd 354:End 253:End 156:OMA 132:MGI 52:PDB 2727:: 1988:EC 1982:: 1899:. 1887:. 1870:. 1862:. 1852:76 1850:. 1846:. 1826:. 1818:. 1810:. 1798:. 1781:. 1767:. 1763:. 1746:. 1738:. 1728:58 1726:. 1709:. 1697:. 1680:. 1670:. 1656:. 1652:. 1635:. 1625:. 1611:. 1607:. 1590:. 1578:. 1561:. 1551:. 1541:91 1539:. 1535:. 1507:. 1499:. 1491:. 1479:. 1453:^ 1439:. 1427:. 1404:. 1394:. 1382:. 1363:. 1345:. 1316:^ 1295:^ 1283:. 1224:. 740:/ 360:bp 347:bp 259:bp 246:bp 154:; 150:: 146:; 142:: 138:; 134:: 130:; 126:: 2713:e 2706:t 2699:v 2688:. 2639:: 2625:) 2621:( 2612:) 2608:( 2599:) 2595:( 2586:) 2582:( 2573:) 2569:( 2560:) 2556:( 2547:) 2543:( 2367:e 2360:t 2353:v 1993:) 1986:( 1972:e 1965:t 1958:v 1945:. 1907:. 1895:: 1878:. 1858:: 1834:. 1814:: 1806:: 1789:. 1775:: 1754:. 1734:: 1717:. 1705:: 1688:. 1664:: 1658:6 1643:. 1619:: 1613:5 1598:. 1586:: 1569:. 1547:: 1515:. 1495:: 1487:: 1464:. 1447:. 1435:: 1412:. 1390:: 1367:. 1349:. 1249:M 1245:A 1241:D 1238:A 1236:( 278:) 175:) 158:: 27:.

Index

Adam22
PDB
PDBe
RCSB
3G5C
Aliases
ADAM22
OMIM
603709
MGI
1340046
HomoloGene
37898
GeneCards
ADAM22
OMA
ADAM22 - orthologs
Human
Chromosome 7 (human)
Chr.
Chromosome 7 (human)
Chromosome 7 (human)
Genomic location for ADAM22
Genomic location for ADAM22
Band
bp
bp
Mouse
Chromosome 5 (mouse)
Chr.

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.

↑