242:
219:
116:
141:
248:
147:
1722:
1066:
are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular gene spans about 20 kb of genomic DNA and is composed of 9 coding exons. The gene encodes a single transcript of 2.8 kb that is highly
1067:
expressed in kidney and lung. The functional significance of this gene and the cellular localization of its product are presently unknown. Two transcript variants encoding different isoforms have been found for this gene.
1419:
Wang Y, Hu Y, Fang Y, Zhang K, Yang H, Ma J, Xu Q, Shen Y (Jun 2009). "Evidence of epistasis between the catechol-O-methyltransferase and aldehyde dehydrogenase 3B1 genes in paranoid schizophrenia".
255:
154:
1529:
1275:
Sun X, Jia Y, Zhang X, Xu Q, Shen Y, Li Y (Jun 2005). "Multi-locus association study of schizophrenia susceptibility genes with a posterior probability method".
1386:"Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects"
1694:
1684:
1669:
1664:
1659:
1628:
1494:
741:
77:
722:
1701:
1196:
Hsu LC, Chang WC, Yoshida A (Apr 1997). "Human aldehyde dehydrogenase genes, ALDH7 and ALDH8: genomic organization and gene structure comparison".
1791:
1767:
1786:
1522:
1143:
1125:
241:
1248:
977:
1312:
Hsu LC, Chang WC, Yoshida A (Dec 1994). "Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family".
1161:
Hsu LC, Chang WC, Yoshida A (Dec 1994). "Cloning of a cDNA encoding human ALDH7, a new member of the aldehyde dehydrogenase family".
218:
1633:
984:
1515:
1231:
1112:
1091:
1254:
140:
115:
1108:
1087:
57:
254:
153:
247:
146:
1760:
1542:
786:
65:
767:
1538:
1063:
1753:
129:
1260:
939:
935:
931:
927:
876:
872:
868:
860:
44:
1444:
1300:
89:
960:
923:
897:
864:
550:
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
1479:
1436:
1407:
1372:
1329:
1292:
1213:
1178:
37:
1737:
85:
1469:
1428:
1397:
1362:
1354:
1321:
1284:
1205:
1170:
334:
265:
209:
164:
309:
1474:
1457:
1367:
1342:
1209:
656:
651:
646:
641:
636:
631:
626:
621:
616:
600:
595:
590:
585:
580:
575:
570:
565:
549:
544:
540:
535:
530:
525:
1780:
1733:
1603:
1507:
1498:
1325:
1174:
512:
1448:
1304:
69:
1432:
327:
106:
93:
1148:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1130:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1358:
410:
226:
123:
73:
686:
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348:
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179:
81:
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1411:
1376:
1296:
1483:
1333:
1217:
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1024:
1019:
1689:
1008:
835:
816:
812:
1402:
1385:
1679:
1674:
1643:
1590:
1585:
1577:
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1560:
1288:
798:
753:
1044:
992:
708:
1721:
1612:
671:
667:
1729:
1051:
61:
1511:
1343:"Expression and initial characterization of human ALDH3B1"
48:, ALDH4, ALDH7, aldehyde dehydrogenase 3 family member B1
317:
1741:
482:
1652:
1621:
1601:
1550:
1456:Yoshida A, Rzhetsky A, Hsu LC, Chang C (Feb 1998).
1347:
953:
916:
890:
853:
1104:
1102:
1100:
1083:
1081:
1079:
1341:Marchitti SA, Orlicky DJ, Vasiliou V (May 2007).
264:
163:
16:Protein-coding gene in the species Homo sapiens
1109:GRCm38: Ensembl release 89: ENSMUSG00000024885
1761:
1523:
526:3-chloroallyl aldehyde dehydrogenase activity
8:
1384:Saito A, Kawamoto M, Kamatani N (Jun 2009).
1088:GRCh38: Ensembl release 89: ENSG00000006534
1768:
1754:
1530:
1516:
1508:
1495:United States National Library of Medicine
1458:"Human aldehyde dehydrogenase gene family"
1037:Aldehyde dehydrogenase 3 family, member B1
682:
508:
305:
204:
101:
1473:
1401:
1366:
1493:This article incorporates text from the
1277:Science in China Series C: Life Sciences
1075:
1675:α-Aminoadipic semialdehyde — (ALDH7A1)
545:aldehyde dehydrogenase (NAD+) activity
18:
642:cellular response to oxidative stress
269:
230:
225:
168:
127:
122:
7:
1718:
1716:
1702:Glyceraldehyde 3-phosphate — (GAPDH)
1629:Dimeric NADP-preferring — (ALDH3A1)
637:cellular aldehyde metabolic process
1740:. You can help Knowledge (XXG) by
1475:10.1046/j.1432-1327.1998.2510549.x
950:
913:
887:
850:
826:
803:
777:
758:
732:
713:
487:
405:
343:
322:
14:
1047:that in humans is encoded by the
632:sphingolipid biosynthetic process
1720:
1462:European Journal of Biochemistry
253:
246:
240:
217:
152:
145:
139:
114:
1792:Human chromosome 11 gene stubs
1433:10.1016/j.biopsych.2008.11.027
471:More reference expression data
367:olfactory zone of nasal mucosa
1:
1210:10.1016/S0378-1119(96)00839-6
238:
137:
1787:Genes on human chromosome 11
1326:10.1016/0378-1119(94)90672-6
1175:10.1016/0378-1119(94)90672-6
429:Epithelium of choroid plexus
1808:
1715:
1634:Fatty aldehyde — (ALDH3A2)
1359:10.1016/j.bbrc.2007.03.046
1259:gene details page in the
627:aldehyde catabolic process
586:secretory granule membrane
1582:Formyltetrahydrofolate —
1390:Journal of Human Genetics
1144:"Mouse PubMed Reference:"
1126:"Human PubMed Reference:"
1023:
1018:
1014:
1007:
991:
972:
957:
920:
909:
894:
857:
846:
833:
829:
810:
806:
797:
784:
780:
765:
761:
752:
739:
735:
720:
716:
707:
692:
685:
681:
665:
652:alcohol metabolic process
617:ethanol catabolic process
591:specific granule membrane
511:
507:
495:
490:
481:
468:
417:
408:
383:mucosa of paranasal sinus
359:bronchial epithelial cell
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
978:Chr 11: 68.01 – 68.03 Mb
657:neutrophil degranulation
1539:Aldehyde dehydrogenases
1064:aldehyde dehydrogenases
541:aldehyde dehydrogenase
536:oxidoreductase activity
1232:"Entrez Gene: ALDH3B1"
985:Chr 19: 3.96 – 3.98 Mb
1421:Biological Psychiatry
581:extracellular exosome
441:stroma of bone marrow
232:Chromosome 19 (mouse)
130:Chromosome 11 (human)
1253:genome location and
1403:10.1038/jhg.2009.31
1261:UCSC Genome Browser
453:seminiferous tubule
94:ALDH3B1 - orthologs
1728:This article on a
1497:, which is in the
1289:10.1007/bf03183620
787:ENSMUSG00000024885
610:Biological process
559:Cellular component
519:Molecular function
449:tibiofemoral joint
391:thoracic diaphragm
363:right uterine tube
1749:
1748:
1710:
1709:
1034:
1033:
1030:
1029:
1003:
1002:
968:
967:
947:
946:
905:
904:
884:
883:
842:
841:
823:
822:
793:
792:
774:
773:
748:
747:
729:
728:
677:
676:
503:
502:
499:
498:
477:
476:
464:
463:
402:
401:
300:
299:
199:
198:
1799:
1770:
1763:
1756:
1724:
1717:
1557:Retinaldehyde —
1532:
1525:
1518:
1509:
1487:
1477:
1452:
1415:
1405:
1380:
1370:
1337:
1308:
1236:
1235:
1228:
1222:
1221:
1193:
1187:
1186:
1158:
1152:
1151:
1140:
1134:
1133:
1122:
1116:
1106:
1095:
1085:
1016:
1015:
987:
980:
963:
951:
942:
914:
910:RefSeq (protein)
900:
888:
879:
851:
827:
804:
778:
759:
733:
714:
683:
622:lipid metabolism
509:
488:
473:
413:
411:Top expressed in
406:
371:nasal epithelium
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
1807:
1806:
1802:
1801:
1800:
1798:
1797:
1796:
1777:
1776:
1775:
1774:
1713:
1711:
1706:
1648:
1617:
1597:
1546:
1536:
1505:
1490:
1455:
1427:(12): 1048–54.
1418:
1383:
1340:
1311:
1274:
1270:
1268:Further reading
1244:
1239:
1230:
1229:
1225:
1195:
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1190:
1160:
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1155:
1142:
1141:
1137:
1124:
1123:
1119:
1107:
1098:
1086:
1077:
1073:
1060:
1025:View/Edit Mouse
1020:View/Edit Human
983:
976:
973:Location (UCSC)
959:
938:
934:
930:
926:
922:
896:
875:
871:
867:
863:
859:
815:
768:ENSG00000006534
661:
605:
576:plasma membrane
554:
531:protein binding
469:
460:
455:
451:
447:
443:
439:
437:right lung lobe
435:
431:
427:
423:
409:
398:
393:
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381:
377:
373:
369:
365:
361:
347:
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278:
270:
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258:
251:
231:
208:Gene location (
190:
177:
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150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
1805:
1803:
1795:
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1563:
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1537:
1535:
1534:
1527:
1520:
1512:
1489:
1488:
1453:
1416:
1381:
1338:
1320:(1–2): 285–9.
1309:
1271:
1269:
1266:
1265:
1264:
1243:
1242:External links
1240:
1238:
1237:
1223:
1188:
1169:(1–2): 285–9.
1153:
1135:
1117:
1096:
1074:
1072:
1069:
1059:
1056:
1039:also known as
1032:
1031:
1028:
1027:
1022:
1012:
1011:
1005:
1004:
1001:
1000:
998:
996:
989:
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372:
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331:
320:
314:
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310:RNA expression
302:
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126:
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119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
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28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1804:
1793:
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1788:
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1784:
1782:
1771:
1766:
1764:
1759:
1757:
1752:
1751:
1745:
1743:
1739:
1735:
1734:chromosome 11
1731:
1726:
1723:
1719:
1714:
1703:
1700:
1699:
1696:
1693:
1691:
1688:
1686:
1683:
1681:
1678:
1676:
1673:
1671:
1668:
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1663:
1661:
1658:
1657:
1655:
1651:
1645:
1642:
1640:
1637:
1635:
1632:
1630:
1627:
1626:
1624:
1620:
1614:
1611:
1610:
1608:
1605:
1604:mitochondrial
1600:
1592:
1589:
1587:
1584:
1583:
1581:
1579:
1576:
1572:
1569:
1567:
1564:
1562:
1559:
1558:
1556:
1555:
1553:
1549:
1544:
1540:
1533:
1528:
1526:
1521:
1519:
1514:
1513:
1510:
1506:
1503:
1502:
1500:
1499:public domain
1496:
1485:
1481:
1476:
1471:
1468:(3): 549–57.
1467:
1463:
1459:
1454:
1450:
1446:
1442:
1438:
1434:
1430:
1426:
1422:
1417:
1413:
1409:
1404:
1399:
1396:(6): 317–23.
1395:
1391:
1387:
1382:
1378:
1374:
1369:
1364:
1360:
1356:
1352:
1348:
1344:
1339:
1335:
1331:
1327:
1323:
1319:
1315:
1310:
1306:
1302:
1298:
1294:
1290:
1286:
1282:
1278:
1273:
1272:
1267:
1262:
1258:
1257:
1252:
1251:
1246:
1245:
1241:
1233:
1227:
1224:
1219:
1215:
1211:
1207:
1203:
1199:
1192:
1189:
1184:
1180:
1176:
1172:
1168:
1164:
1157:
1154:
1149:
1145:
1139:
1136:
1131:
1127:
1121:
1118:
1114:
1110:
1105:
1103:
1101:
1097:
1093:
1089:
1084:
1082:
1080:
1076:
1070:
1068:
1065:
1057:
1055:
1053:
1050:
1046:
1042:
1038:
1026:
1021:
1017:
1013:
1010:
1006:
999:
997:
994:
990:
986:
982:
979:
975:
971:
964:
962:
956:
952:
949:
943:
941:
937:
933:
929:
925:
919:
915:
912:
908:
901:
899:
893:
889:
886:
880:
878:
874:
870:
866:
862:
856:
852:
849:
847:RefSeq (mRNA)
845:
838:
837:
832:
828:
825:
819:
818:
814:
809:
805:
802:
800:
796:
789:
788:
783:
779:
776:
770:
769:
764:
760:
757:
755:
751:
744:
743:
738:
734:
731:
725:
724:
719:
715:
712:
710:
706:
703:
700:
698:
695:
691:
688:
684:
680:
673:
669:
664:
658:
655:
653:
650:
648:
645:
643:
640:
638:
635:
633:
630:
628:
625:
623:
620:
618:
615:
614:
612:
609:
608:
602:
599:
597:
594:
592:
589:
587:
584:
582:
579:
577:
574:
572:
569:
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564:
563:
561:
558:
557:
551:
548:
546:
543:
539:
537:
534:
532:
529:
527:
524:
523:
521:
518:
517:
514:
513:Gene ontology
510:
506:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
432:
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412:
407:
404:
394:
390:
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378:
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370:
366:
362:
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354:
350:
345:
342:
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329:
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321:
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315:
311:
307:
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295:
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277:
267:
263:
256:
249:
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236:
228:
224:
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215:
211:
206:
202:
194:
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181:
176:
166:
162:
155:
148:
142:
135:
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125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
1742:expanding it
1727:
1712:
1638:
1504:
1492:
1491:
1465:
1461:
1424:
1420:
1393:
1389:
1353:(3): 792–8.
1350:
1346:
1317:
1313:
1283:(3): 263–9.
1280:
1276:
1255:
1249:
1226:
1204:(1): 89–94.
1201:
1197:
1191:
1166:
1162:
1156:
1147:
1138:
1129:
1120:
1061:
1048:
1040:
1036:
1035:
958:
940:NP_001276988
936:NP_001276987
932:NP_001154945
928:NP_001025181
921:
895:
877:NM_001290058
873:NM_001161473
869:NM_001030010
861:NM_001290059
858:
834:
811:
785:
766:
740:
721:
701:
696:
433:right kidney
333:
326:
271:19|19 A
53:External IDs
421:granulocyte
387:granulocyte
191:68,029,282
178:68,008,578
31:Identifiers
1781:Categories
1602:Family 2 (
1115:, May 2017
1094:, May 2017
1071:References
647:metabolism
379:right lung
337:(ortholog)
292:3,979,808
279:3,963,491
74:HomoloGene
1732:on human
961:NP_080592
924:NP_000685
898:NM_026316
865:NM_000694
687:Orthologs
596:cytoplasm
425:spermatid
395:beta cell
82:GeneCards
1695:ALDH18A1
1690:ALDH16A1
1622:Family 3
1551:Family 1
1449:25166866
1441:19159868
1412:19343046
1377:17382292
1305:19136391
1297:16092759
1111:–
1090:–
1058:Function
1009:Wikidata
666:Sources:
571:membrane
445:duodenum
375:monocyte
1685:ALDH9A1
1680:ALDH8A1
1670:ALDH6A1
1665:ALDH5A1
1660:ALDH4A1
1644:ALDH3B2
1639:ALDH3B1
1591:ALDH1L2
1586:ALDH1L1
1578:ALDH1B1
1571:ALDH1A3
1566:ALDH1A2
1561:ALDH1A1
1484:9490025
1368:1899873
1334:7828891
1256:ALDH3B1
1250:ALDH3B1
1218:9161417
1183:7828891
1113:Ensembl
1092:Ensembl
1049:ALDH3B1
1041:ALDH3B1
799:UniProt
754:Ensembl
693:Species
672:QuickGO
601:cytosol
566:vesicle
457:jejunum
312:pattern
170:11q13.2
86:ALDH3B1
70:1914939
45:ALDH3B1
38:Aliases
22:ALDH3B1
1545:1.2.1)
1482:
1447:
1439:
1410:
1375:
1365:
1332:
1303:
1295:
1247:Human
1216:
1181:
1045:enzyme
1043:is an
995:search
993:PubMed
836:Q80VQ0
817:Q9BUJ8
813:P43353
709:Entrez
483:BioGPS
62:600466
1736:is a
1653:Other
1613:ALDH2
1445:S2CID
1301:S2CID
742:67689
702:Mouse
697:Human
668:Amigo
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
78:73890
1738:stub
1730:gene
1480:PMID
1437:PMID
1408:PMID
1373:PMID
1330:PMID
1314:Gene
1293:PMID
1214:PMID
1198:Gene
1179:PMID
1163:Gene
1062:The
1052:gene
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
58:OMIM
1470:doi
1466:251
1429:doi
1398:doi
1363:PMC
1355:doi
1351:356
1322:doi
1318:151
1285:doi
1206:doi
1202:189
1171:doi
1167:151
723:221
491:n/a
288:End
187:End
90:OMA
66:MGI
1783::
1543:EC
1478:.
1464:.
1460:.
1443:.
1435:.
1425:65
1423:.
1406:.
1394:54
1392:.
1388:.
1371:.
1361:.
1349:.
1345:.
1328:.
1316:.
1299:.
1291:.
1281:48
1279:.
1212:.
1200:.
1177:.
1165:.
1146:.
1128:.
1099:^
1078:^
1054:.
670:/
294:bp
281:bp
193:bp
180:bp
88:;
84::
80:;
76::
72:;
68::
64:;
60::
1769:e
1762:t
1755:v
1744:.
1606:)
1541:(
1531:e
1524:t
1517:v
1501:.
1486:.
1472::
1451:.
1431::
1414:.
1400::
1379:.
1357::
1336:.
1324::
1307:.
1287::
1263:.
1234:.
1220:.
1208::
1185:.
1173::
1150:.
1132:.
212:)
109:)
92::
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