3052:
319:
296:
193:
218:
577:
570:
325:
224:
42:
1513:. It is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. ApoA-II regulates many steps in HDL metabolism, and its role in coronary heart disease is unclear. Remarkably, defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.
1368:
3350:
68:
2063:"Isolation and characterization of the human apolipoprotein A-II gene. Electron microscopic analysis of RNA:DNA hybrids, nucleotide sequence, identification of a polymorphic MspI site, and general structural organization of apolipoprotein genes"
1866:
1554:
2307:
Vollmer E, Brust J, Roessner A, Bosse A, Burwikel F, Kaesberg B, Harrach B, Robenek H, Böcker W (1991). "Distribution patterns of apolipoproteins A1, A2, and B in the wall of atherosclerotic vessels".
2699:
Moore MN, Kao FT, Tsao YK, Chan L (Aug 1984). "Human apolipoprotein A-II: nucleotide sequence of a cloned cDNA, and localization of its structural gene on human chromosome 1".
3274:
3254:
332:
231:
2958:
2582:
Shelley CS, Sharpe CR, Baralle FE, Shoulders CC (Nov 1985). "Comparison of the human apolipoprotein genes. Apo AII presents a unique functional intron-exon junction".
1467:
3302:
3051:
2849:
Stoffel W, Krüger E, Deutzmann R (Mar 1983). "Cell-free translation of human liver apolipoprotein AI and AII mRNA. Processing of primary translation products".
2165:"Binding of phospholipid transfer protein (PLTP) to apolipoproteins A-I and A-II: location of a PLTP binding domain in the amino terminal region of apoA-I"
1075:
154:
1056:
3164:
2878:
Knott TJ, Priestley LM, Urdea M, Scott J (May 1984). "Isolation and characterisation of a cDNA encoding the precursor for human apolipoprotein AII".
3197:
2381:"Extracellular processing of proapolipoprotein A-II in Hep G2 cell cultures is mediated by a 54-kDa protease immunologically related to cathepsin B"
1906:
1594:
2270:
Kalopissis AD, Pastier D, Chambaz J (Apr 2003). "Apolipoprotein A-II: beyond genetic associations with lipid disorders and insulin resistance".
1909:
1597:
3424:
1879:
1567:
3395:
2527:
2043:
1415:
3414:
3229:
2951:
2666:"Isolation and characterization of the tryptic and cyanogen bromide peptides of apoLp-Gln-II (apoA-II), plasma high density apolipoprotein"
2545:
Middleton-Price HR, van den Berghe JA, Scott J, Knott TJ, Malcolm S (Jul 1988). "Regional chromosomal localisation of APOA2 to 1q21-1q23".
2025:
1878:
1566:
1897:
1585:
1299:
318:
2208:
1306:
1913:
1601:
3192:
2907:
Lackner KJ, Law SW, Brewer HB, Sakaguchi AY, Naylor SL (Aug 1984). "The human apolipoprotein A-II gene is located on chromosome 1".
295:
1899:
1587:
3312:
3015:
2149:
1910:
1598:
2944:
2012:
1991:
2008:
1876:
1564:
1487:
2613:"Amino acid sequence of human apoLp-Gln-II (apoA-II), an apolipoprotein isolated from the high-density lipoprotein complex"
2214:
1912:
1892:
1886:
1881:
1600:
1580:
1574:
1569:
217:
192:
65:
3202:
3184:
1904:
1884:
1592:
1572:
1526:
1987:
3001:
1936:
1877:
1565:
134:
1372:
structures of apolipoprotein a-ii and a lipid surrogate complex provide insights into apolipoprotein-lipid interactions
1895:
1894:
1873:
1583:
1582:
1561:
1522:
1914:
1903:
1890:
1889:
1888:
1602:
1591:
1578:
1577:
1576:
331:
230:
1907:
1893:
1595:
1581:
1911:
1908:
1599:
1596:
324:
223:
3388:
1891:
1579:
1917:
1916:
1874:
1870:
1605:
1604:
1562:
1558:
3419:
3036:
1915:
1905:
1902:
1901:
1900:
1885:
1883:
1882:
1880:
1872:
1871:
1869:
1603:
1593:
1590:
1589:
1588:
1573:
1571:
1570:
1568:
1560:
1559:
1557:
1120:
142:
1898:
1887:
1875:
1586:
1575:
1563:
1475:
1896:
1584:
3020:
1101:
3212:
2237:"Role of apoA-II in lipid metabolism and atherosclerosis: advances in the study of an enigmatic protein"
1471:
3381:
2624:
1428:
206:
3041:
2220:
1278:
1274:
1270:
1223:
1219:
1215:
121:
3174:
2759:
2570:
2332:
2295:
166:
2511:
2502:
1282:
1249:
1211:
1190:
3116:
3111:
3106:
3101:
3071:
3011:
2924:
2895:
2866:
2837:
2794:
2751:
2716:
2687:
2652:
2599:
2562:
2533:
2523:
2488:
2445:
2402:
2367:
2324:
2287:
2258:
2186:
2131:
2123:
2084:
1462:
576:
114:
58:
3365:
2416:"The human apolipoprotein A-II gene: complete nucleic acid sequence and genomic organization"
3143:
3133:
3128:
3123:
3093:
2916:
2887:
2858:
2827:
2819:
2784:
2741:
2708:
2677:
2642:
2632:
2591:
2554:
2515:
2478:
2470:
2435:
2427:
2392:
2357:
2316:
2279:
2248:
2176:
2115:
2074:
411:
342:
286:
241:
3289:
3264:
1454:
569:
162:
3138:
2936:
386:
2628:
2163:
Pussinen PJ, Jauhiainen M, Metso J, Pyle LE, Marcel YL, Fidge NH, Ehnholm C (Jan 1998).
3169:
3060:
3031:
2457:
Knott TJ, Wallis SC, Robertson ME, Priestley LM, Urdea M, Rall LB, Scott J (Sep 1985).
2362:
2345:
41:
2891:
2832:
2807:
2789:
2772:
2682:
2665:
2647:
2612:
2483:
2458:
2440:
2415:
2397:
2380:
2253:
2236:
2181:
2164:
2119:
2079:
2062:
1957:
1940:
1927:
990:
985:
980:
975:
970:
965:
960:
955:
950:
945:
940:
935:
930:
925:
920:
915:
910:
905:
900:
895:
890:
885:
880:
875:
870:
865:
860:
855:
850:
845:
840:
835:
830:
825:
820:
815:
810:
805:
800:
795:
790:
785:
780:
775:
759:
754:
749:
744:
739:
734:
729:
724:
719:
714:
709:
693:
688:
683:
678:
673:
668:
663:
658:
653:
648:
643:
638:
633:
628:
623:
618:
3408:
2920:
2746:
2729:
2712:
2595:
2519:
2283:
1420:
605:
2574:
2459:"The human apolipoprotein AII gene: structural organization and sites of expression"
2346:"A splice-junction mutation responsible for familial apolipoprotein A-II deficiency"
2336:
1865:
1553:
1396:
3361:
3297:
2992:
2763:
2299:
1450:
404:
183:
146:
2862:
2806:
Sharpe CR, Sidoli A, Shelley CS, Lucero MA, Shoulders CC, Baralle FE (May 1984).
1408:
170:
3007:
2996:
2980:
2971:
2808:"Human apolipoproteins AI, AII, CII and CIII. cDNA sequences and mRNA abundance"
2048:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2030:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2771:
Gordon JI, Budelier KA, Sims HF, Edelstein C, Scanu AM, Strauss AW (Nov 1983).
2617:
Proceedings of the
National Academy of Sciences of the United States of America
487:
1538:
Click on genes, proteins and metabolites below to link to respective articles.
303:
200:
150:
2730:"Human apolipoprotein A-II: complete nucleic acid sequence of preproapo A-II"
2474:
2431:
2127:
2823:
1020:
547:
425:
370:
357:
269:
256:
158:
2637:
2503:"Molecular cloning and sequence analysis of human apolipoprotein A-II cDNA"
2291:
2262:
2135:
2103:
2928:
2899:
2870:
2841:
2798:
2755:
2720:
2691:
2656:
2603:
2566:
2537:
2492:
2449:
2406:
2371:
2328:
2190:
2088:
1424:
1367:
1346:
1341:
2508:
Plasma
Lipoproteins Part A: Preparation, Structure, and Molecular Biology
1403:
1330:
1165:
1146:
2558:
2320:
1503:
1132:
1087:
781:
negative regulation of very-low-density lipoprotein particle remodeling
826:
negative regulation of cytokine production involved in immune response
91:
87:
3221:
3156:
1482:
1314:
1042:
17:
3349:
2235:
Blanco-Vaca F, Escolà-Gil JC, Martín-Campos JM, Julve J (Nov 2001).
3332:
3327:
3322:
3284:
3279:
3239:
3086:
3081:
3076:
2967:
2379:
Gordon JI, Sims HF, Edelstein C, Scanu AM, Strauss AW (Nov 1985).
1005:
1001:
3357:
3269:
3259:
3249:
3244:
3234:
1510:
1444:
1391:
138:
2940:
664:
phosphatidylcholine-sterol O-acyltransferase activator activity
2344:
Deeb SS, Takata K, Peng RL, Kajiyama G, Albers JJ (Apr 1990).
2102:
Tailleux A, Duriez P, Fruchart JC, Clavey V (September 2002).
585:
2061:
Tsao YK, Wei CF, Robberson DL, Gotto AM, Chan L (Dec 1985).
1864:
1552:
1955:
The interactive pathway map can be edited at WikiPathways:
2104:"Apolipoprotein A-II, HDL metabolism and atherosclerosis"
394:
3369:
911:
negative regulation of cholesterol transporter activity
559:
2851:
3311:
3211:
3183:
3154:
3059:
2979:
2909:
2880:
2701:
1481:
1461:
1443:
1438:
1414:
1402:
1390:
1382:
1377:
1360:
1263:
1242:
1204:
1183:
2501:
2004:
2002:
2000:
1983:
1981:
1979:
644:high-density lipoprotein particle receptor binding
2773:"Biosynthesis of human preproapolipoprotein A-II"
2510:. Methods in Enzymology. Vol. 128. pp.
926:triglyceride-rich lipoprotein particle remodeling
801:positive regulation of cholesterol esterification
341:
240:
2664:Lux SE, John KM, Ronan R, Brewer HB (Dec 1972).
2611:Brewer HB, Lux SE, Ronan R, John KM (May 1972).
1868:
1556:
861:regulation of intestinal cholesterol absorption
27:Protein-coding gene in the species Homo sapiens
2009:GRCm38: Ensembl release 89: ENSMUSG00000005681
921:negative regulation of lipid catabolic process
816:positive regulation of lipid catabolic process
3389:
2952:
125:, Apo-AII, ApoA-II, apoAII, Apolipoprotein A2
8:
896:negative regulation of cholesterol transport
851:high-density lipoprotein particle remodeling
1988:GRCh38: Ensembl release 89: ENSG00000158874
941:high-density lipoprotein particle clearance
866:low-density lipoprotein particle remodeling
735:spherical high-density lipoprotein particle
3396:
3382:
2959:
2945:
2937:
2728:Lackner KJ, Law SW, Brewer HB (Sep 1984).
2414:Lackner KJ, Law SW, Brewer HB (Jun 1985).
1435:
1366:
1016:
836:high-density lipoprotein particle assembly
601:
382:
281:
178:
76:
2831:
2788:
2745:
2681:
2646:
2636:
2482:
2439:
2396:
2361:
2252:
2180:
2078:
946:positive regulation of catalytic activity
776:negative regulation of cholesterol import
684:high-density lipoprotein particle binding
506:fetal liver hematopoietic progenitor cell
2150:"Entrez Gene: APOA2 apolipoprotein A-II"
906:phosphatidylcholine biosynthetic process
1975:
1948:
976:post-translational protein modification
1357:
856:negative regulation of lipase activity
31:
956:regulation of lipid metabolic process
730:very-low-density lipoprotein particle
346:
307:
302:
245:
204:
199:
7:
3346:
3344:
2777:The Journal of Biological Chemistry
2670:The Journal of Biological Chemistry
2385:The Journal of Biological Chemistry
2067:The Journal of Biological Chemistry
986:positive regulation of phagocytosis
659:protein heterodimerization activity
3368:. You can help Knowledge (XXG) by
2500:Chan L, Moore MN, Tsao YK (1986).
2350:American Journal of Human Genetics
1260:
1239:
1201:
1180:
1156:
1137:
1111:
1092:
1066:
1047:
564:
482:
420:
399:
25:
1506:that in humans is encoded by the
750:high-density lipoprotein particle
624:protein homodimerization activity
3348:
3050:
2284:10.1097/00041433-200304000-00008
886:peptidyl-methionine modification
786:diacylglycerol catabolic process
575:
568:
330:
323:
317:
294:
229:
222:
216:
191:
40:
796:regulation of protein stability
639:apolipoprotein receptor binding
931:triglyceride metabolic process
881:phospholipid catabolic process
586:More reference expression data
548:More reference expression data
1:
3425:Human chromosome 1 gene stubs
2892:10.1016/S0006-291X(84)80168-0
2790:10.1016/S0021-9258(17)44023-3
2683:10.1016/S0021-9258(19)44556-0
2398:10.1016/S0021-9258(17)38646-5
2272:Current Opinion in Lipidology
2254:10.1016/S0022-2275(20)31499-1
2182:10.1016/S0022-2275(20)34211-5
2120:10.1016/s0021-9150(01)00751-1
2080:10.1016/S0021-9258(18)95725-X
1527:phospholipid transfer protein
1439:Available protein structures:
971:lipoprotein metabolic process
951:cholesterol metabolic process
936:reverse cholesterol transport
674:cholesterol transfer activity
315:
214:
2921:10.1016/0006-291X(84)91172-0
2863:10.1515/bchm2.1983.364.1.227
2747:10.1016/0014-5793(84)80590-6
2713:10.1016/0006-291X(84)90371-1
2596:10.1016/0022-2836(85)90255-4
2584:Journal of Molecular Biology
2520:10.1016/0076-6879(86)28103-3
3415:Genes on human chromosome 1
871:acute inflammatory response
720:endoplasmic reticulum lumen
629:phosphatidylcholine binding
3441:
3343:
2219:gene details page in the
1521:ApoA-II has been shown to
841:retinoid metabolic process
821:response to glucocorticoid
694:signaling receptor binding
689:heat shock protein binding
634:lipid transporter activity
534:sexually immature organism
3048:
2241:Journal of Lipid Research
2169:Journal of Lipid Research
2044:"Mouse PubMed Reference:"
2026:"Human PubMed Reference:"
1434:
1365:
1345:
1340:
1336:
1329:
1313:
1307:Chr 1: 171.05 – 171.05 Mb
1300:Chr 1: 161.22 – 161.22 Mb
1294:
1267:
1246:
1235:
1208:
1187:
1176:
1163:
1159:
1144:
1140:
1131:
1118:
1114:
1099:
1095:
1086:
1073:
1069:
1054:
1050:
1041:
1026:
1019:
1015:
999:
876:animal organ regeneration
619:lipase inhibitor activity
604:
600:
583:
567:
558:
545:
494:
485:
432:
423:
393:
385:
381:
364:
351:
314:
293:
284:
280:
263:
250:
213:
190:
181:
177:
132:
129:
119:
112:
107:
84:
79:
62:
57:
52:
48:
39:
34:
468:tendon of biceps brachii
3185:Lipid transfer proteins
1533:Interactive pathway map
901:cholesterol homeostasis
3213:Cell surface receptors
2812:Nucleic Acids Research
2638:10.1073/pnas.69.5.1304
2475:10.1093/nar/13.17.6387
2463:Nucleic Acids Research
2432:10.1093/nar/13.12.4597
2420:Nucleic Acids Research
1958:"Statin_Pathway_WP430"
1920:
1608:
961:chylomicron remodeling
2824:10.1093/nar/12.9.3917
1919:
1607:
991:protein stabilization
811:cholesterol transport
755:extracellular exosome
3315:cassette transporter
2213:genome location and
1926:|alt=Statin pathway
966:chylomicron assembly
846:response to estrogen
740:extracellular region
669:phospholipid binding
348:1 H3|1 79.22 cM
309:Chromosome 1 (mouse)
207:Chromosome 1 (human)
80:List of PDB id codes
53:Available structures
3042:Remnant cholesterol
2974:particle metabolism
2629:1972PNAS...69.1304B
2221:UCSC Genome Browser
1500:Apolipoprotein A-II
831:response to glucose
806:phospholipid efflux
760:extracellular space
715:blood microparticle
649:cholesterol binding
440:epithelium of colon
436:right lobe of liver
3356:This article on a
2559:10.1007/BF00366253
2321:10.1007/BF01600220
1921:
1609:
1121:ENSMUSG00000005681
891:cholesterol efflux
769:Biological process
703:Cellular component
612:Molecular function
498:left lobe of liver
3377:
3376:
3341:
3340:
2529:978-0-12-182028-2
2309:Virchows Archiv A
1497:
1496:
1493:
1492:
1488:structure summary
1356:
1355:
1352:
1351:
1325:
1324:
1290:
1289:
1257:
1256:
1231:
1230:
1198:
1197:
1172:
1171:
1153:
1152:
1127:
1126:
1108:
1107:
1082:
1081:
1063:
1062:
1011:
1010:
596:
595:
592:
591:
554:
553:
541:
540:
479:
478:
464:left uterine tube
456:bone marrow cells
377:
376:
276:
275:
171:APOA2 - orthologs
103:
102:
99:
98:
63:Ortholog search:
16:(Redirected from
3432:
3398:
3391:
3384:
3352:
3345:
3054:
2983:particle classes
2961:
2954:
2947:
2938:
2932:
2903:
2874:
2845:
2835:
2802:
2792:
2767:
2749:
2724:
2695:
2685:
2660:
2650:
2640:
2607:
2578:
2541:
2505:
2496:
2486:
2453:
2443:
2426:(12): 4597–608.
2410:
2400:
2391:(27): 14824–31.
2375:
2365:
2340:
2303:
2266:
2256:
2195:
2194:
2184:
2160:
2154:
2153:
2146:
2140:
2139:
2099:
2093:
2092:
2082:
2073:(28): 15222–31.
2058:
2052:
2051:
2040:
2034:
2033:
2022:
2016:
2006:
1995:
1985:
1962:
1961:
1953:
1860:
1855:
1850:
1845:
1840:
1835:
1830:
1825:
1820:
1815:
1810:
1805:
1800:
1795:
1790:
1785:
1780:
1775:
1770:
1765:
1760:
1755:
1750:
1745:
1740:
1735:
1730:
1725:
1720:
1715:
1710:
1705:
1700:
1695:
1690:
1685:
1680:
1675:
1670:
1665:
1660:
1655:
1650:
1645:
1640:
1635:
1630:
1625:
1620:
1615:
1436:
1370:
1358:
1338:
1337:
1309:
1302:
1285:
1261:
1252:
1240:
1236:RefSeq (protein)
1226:
1202:
1193:
1181:
1157:
1138:
1112:
1093:
1067:
1048:
1017:
602:
588:
579:
572:
565:
550:
490:
488:Top expressed in
483:
428:
426:Top expressed in
421:
400:
383:
373:
360:
349:
334:
327:
321:
310:
298:
282:
272:
259:
248:
233:
226:
220:
209:
195:
179:
173:
124:
117:
94:
77:
71:
50:
49:
44:
32:
21:
3440:
3439:
3435:
3434:
3433:
3431:
3430:
3429:
3420:Apolipoproteins
3405:
3404:
3403:
3402:
3342:
3337:
3314:
3307:
3207:
3179:
3150:
3061:Apolipoproteins
3055:
3046:
2984:
2975:
2965:
2935:
2906:
2877:
2848:
2805:
2783:(22): 14054–9.
2770:
2727:
2698:
2676:(23): 7519–27.
2663:
2610:
2581:
2544:
2530:
2499:
2469:(17): 6387–98.
2456:
2413:
2378:
2343:
2306:
2269:
2247:(11): 1727–39.
2234:
2230:
2228:Further reading
2204:
2199:
2198:
2162:
2161:
2157:
2148:
2147:
2143:
2108:Atherosclerosis
2101:
2100:
2096:
2060:
2059:
2055:
2042:
2041:
2037:
2024:
2023:
2019:
2007:
1998:
1986:
1977:
1972:
1967:
1966:
1965:
1956:
1954:
1950:
1945:
1944:
1943:
1939:Statin pathway
1938:
1933:
1932:
1931:
1925:
1924:
1923:
1922:
1918:
1862:
1861:
1858:
1856:
1853:
1851:
1848:
1846:
1843:
1841:
1838:
1836:
1833:
1831:
1828:
1826:
1823:
1821:
1818:
1816:
1813:
1811:
1808:
1806:
1803:
1801:
1798:
1796:
1793:
1791:
1788:
1786:
1783:
1781:
1778:
1776:
1773:
1771:
1768:
1766:
1763:
1761:
1758:
1756:
1753:
1751:
1748:
1746:
1743:
1741:
1738:
1736:
1733:
1731:
1728:
1726:
1723:
1721:
1718:
1716:
1713:
1711:
1708:
1706:
1703:
1701:
1698:
1696:
1693:
1691:
1688:
1686:
1683:
1681:
1678:
1676:
1673:
1671:
1668:
1666:
1663:
1661:
1658:
1656:
1653:
1651:
1648:
1646:
1643:
1641:
1638:
1636:
1633:
1631:
1628:
1626:
1623:
1621:
1618:
1616:
1613:
1610:
1606:
1535:
1519:
1373:
1347:View/Edit Mouse
1342:View/Edit Human
1305:
1298:
1295:Location (UCSC)
1281:
1277:
1273:
1269:
1248:
1222:
1218:
1214:
1210:
1189:
1102:ENSG00000158874
995:
791:lipid transport
764:
698:
654:protein binding
584:
574:
573:
546:
537:
532:
530:proximal tubule
528:
524:
520:
516:
512:
508:
504:
500:
486:
475:
470:
466:
462:
458:
454:
450:
446:
442:
438:
424:
368:
355:
347:
337:
336:
335:
328:
308:
285:Gene location (
267:
254:
246:
236:
235:
234:
227:
205:
182:Gene location (
133:
120:
113:
86:
64:
28:
23:
22:
15:
12:
11:
5:
3438:
3436:
3428:
3427:
3422:
3417:
3407:
3406:
3401:
3400:
3393:
3386:
3378:
3375:
3374:
3353:
3339:
3338:
3336:
3335:
3330:
3325:
3319:
3317:
3309:
3308:
3306:
3305:
3300:
3294:
3293:
3292:
3287:
3282:
3277:
3272:
3267:
3262:
3257:
3252:
3247:
3242:
3237:
3225:
3224:
3217:
3215:
3209:
3208:
3206:
3205:
3200:
3195:
3189:
3187:
3181:
3180:
3178:
3177:
3172:
3167:
3161:
3159:
3155:Extracellular
3152:
3151:
3149:
3148:
3147:
3146:
3136:
3131:
3126:
3121:
3120:
3119:
3114:
3109:
3104:
3096:
3091:
3090:
3089:
3084:
3079:
3074:
3065:
3063:
3057:
3056:
3049:
3047:
3045:
3044:
3039:
3034:
3029:
3026:
3023:
3018:
3004:
2999:
2988:
2986:
2985:and subclasses
2977:
2976:
2966:
2964:
2963:
2956:
2949:
2941:
2934:
2933:
2904:
2875:
2846:
2818:(9): 3917–32.
2803:
2768:
2725:
2696:
2661:
2608:
2579:
2547:Human Genetics
2542:
2528:
2497:
2454:
2411:
2376:
2341:
2304:
2267:
2231:
2229:
2226:
2225:
2224:
2203:
2202:External links
2200:
2197:
2196:
2155:
2141:
2094:
2053:
2035:
2017:
1996:
1974:
1973:
1971:
1968:
1964:
1963:
1947:
1946:
1935:
1934:
1863:
1857:
1852:
1847:
1842:
1837:
1832:
1827:
1822:
1817:
1812:
1807:
1802:
1797:
1792:
1787:
1782:
1777:
1772:
1767:
1762:
1757:
1752:
1747:
1742:
1737:
1732:
1727:
1722:
1717:
1712:
1707:
1702:
1697:
1692:
1687:
1682:
1677:
1672:
1667:
1662:
1657:
1652:
1647:
1642:
1637:
1632:
1627:
1622:
1617:
1612:
1611:
1551:
1550:
1549:
1548:
1546:
1545:
1544:
1543:
1542:
1541:
1534:
1531:
1518:
1515:
1495:
1494:
1491:
1490:
1485:
1479:
1478:
1465:
1459:
1458:
1448:
1441:
1440:
1432:
1431:
1418:
1412:
1411:
1406:
1400:
1399:
1394:
1388:
1387:
1384:
1380:
1379:
1375:
1374:
1371:
1363:
1362:
1354:
1353:
1350:
1349:
1344:
1334:
1333:
1327:
1326:
1323:
1322:
1320:
1318:
1311:
1310:
1303:
1296:
1292:
1291:
1288:
1287:
1265:
1264:
1258:
1255:
1254:
1244:
1243:
1237:
1233:
1232:
1229:
1228:
1206:
1205:
1199:
1196:
1195:
1185:
1184:
1178:
1174:
1173:
1170:
1169:
1161:
1160:
1154:
1151:
1150:
1142:
1141:
1135:
1129:
1128:
1125:
1124:
1116:
1115:
1109:
1106:
1105:
1097:
1096:
1090:
1084:
1083:
1080:
1079:
1071:
1070:
1064:
1061:
1060:
1052:
1051:
1045:
1039:
1038:
1033:
1028:
1024:
1023:
1013:
1012:
1009:
1008:
997:
996:
994:
993:
988:
983:
978:
973:
968:
963:
958:
953:
948:
943:
938:
933:
928:
923:
918:
913:
908:
903:
898:
893:
888:
883:
878:
873:
868:
863:
858:
853:
848:
843:
838:
833:
828:
823:
818:
813:
808:
803:
798:
793:
788:
783:
778:
772:
770:
766:
765:
763:
762:
757:
752:
747:
745:early endosome
742:
737:
732:
727:
722:
717:
712:
706:
704:
700:
699:
697:
696:
691:
686:
681:
676:
671:
666:
661:
656:
651:
646:
641:
636:
631:
626:
621:
615:
613:
609:
608:
598:
597:
594:
593:
590:
589:
581:
580:
562:
556:
555:
552:
551:
543:
542:
539:
538:
536:
535:
531:
527:
523:
519:
515:
514:abdominal wall
511:
507:
503:
499:
495:
492:
491:
480:
477:
476:
474:
473:
469:
465:
461:
457:
453:
449:
445:
441:
437:
433:
430:
429:
417:
416:
408:
397:
391:
390:
387:RNA expression
379:
378:
375:
374:
366:
362:
361:
353:
350:
345:
339:
338:
329:
322:
316:
312:
311:
306:
300:
299:
291:
290:
278:
277:
274:
273:
265:
261:
260:
252:
249:
244:
238:
237:
228:
221:
215:
211:
210:
203:
197:
196:
188:
187:
175:
174:
131:
127:
126:
118:
110:
109:
105:
104:
101:
100:
97:
96:
82:
81:
73:
72:
61:
55:
54:
46:
45:
37:
36:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
3437:
3426:
3423:
3421:
3418:
3416:
3413:
3412:
3410:
3399:
3394:
3392:
3387:
3385:
3380:
3379:
3373:
3371:
3367:
3363:
3359:
3354:
3351:
3347:
3334:
3331:
3329:
3326:
3324:
3321:
3320:
3318:
3316:
3310:
3304:
3301:
3299:
3295:
3291:
3288:
3286:
3283:
3281:
3278:
3276:
3273:
3271:
3268:
3266:
3263:
3261:
3258:
3256:
3253:
3251:
3248:
3246:
3243:
3241:
3238:
3236:
3233:
3232:
3231:
3227:
3226:
3223:
3219:
3218:
3216:
3214:
3210:
3204:
3201:
3199:
3196:
3194:
3191:
3190:
3188:
3186:
3182:
3176:
3173:
3171:
3168:
3166:
3163:
3162:
3160:
3158:
3153:
3145:
3142:
3141:
3140:
3137:
3135:
3132:
3130:
3127:
3125:
3122:
3118:
3115:
3113:
3110:
3108:
3105:
3103:
3100:
3099:
3097:
3095:
3092:
3088:
3085:
3083:
3080:
3078:
3075:
3073:
3070:
3069:
3067:
3066:
3064:
3062:
3058:
3053:
3043:
3040:
3038:
3035:
3033:
3030:
3027:
3024:
3022:
3019:
3017:
3013:
3009:
3005:
3003:
3000:
2998:
2994:
2990:
2989:
2987:
2982:
2978:
2973:
2969:
2962:
2957:
2955:
2950:
2948:
2943:
2942:
2939:
2930:
2926:
2922:
2918:
2915:(3): 877–83.
2914:
2910:
2905:
2901:
2897:
2893:
2889:
2886:(3): 734–40.
2885:
2881:
2876:
2872:
2868:
2864:
2860:
2857:(3): 227–37.
2856:
2852:
2847:
2843:
2839:
2834:
2829:
2825:
2821:
2817:
2813:
2809:
2804:
2800:
2796:
2791:
2786:
2782:
2778:
2774:
2769:
2765:
2761:
2757:
2753:
2748:
2743:
2740:(1): 159–64.
2739:
2735:
2731:
2726:
2722:
2718:
2714:
2710:
2706:
2702:
2697:
2693:
2689:
2684:
2679:
2675:
2671:
2667:
2662:
2658:
2654:
2649:
2644:
2639:
2634:
2630:
2626:
2623:(5): 1304–8.
2622:
2618:
2614:
2609:
2605:
2601:
2597:
2593:
2589:
2585:
2580:
2576:
2572:
2568:
2564:
2560:
2556:
2552:
2548:
2543:
2539:
2535:
2531:
2525:
2521:
2517:
2513:
2509:
2504:
2498:
2494:
2490:
2485:
2480:
2476:
2472:
2468:
2464:
2460:
2455:
2451:
2447:
2442:
2437:
2433:
2429:
2425:
2421:
2417:
2412:
2408:
2404:
2399:
2394:
2390:
2386:
2382:
2377:
2373:
2369:
2364:
2359:
2355:
2351:
2347:
2342:
2338:
2334:
2330:
2326:
2322:
2318:
2314:
2310:
2305:
2301:
2297:
2293:
2289:
2285:
2281:
2278:(2): 165–72.
2277:
2273:
2268:
2264:
2260:
2255:
2250:
2246:
2242:
2238:
2233:
2232:
2227:
2222:
2218:
2217:
2212:
2211:
2206:
2205:
2201:
2192:
2188:
2183:
2178:
2175:(1): 152–61.
2174:
2170:
2166:
2159:
2156:
2151:
2145:
2142:
2137:
2133:
2129:
2125:
2121:
2117:
2113:
2109:
2105:
2098:
2095:
2090:
2086:
2081:
2076:
2072:
2068:
2064:
2057:
2054:
2049:
2045:
2039:
2036:
2031:
2027:
2021:
2018:
2014:
2010:
2005:
2003:
2001:
1997:
1993:
1989:
1984:
1982:
1980:
1976:
1969:
1959:
1952:
1949:
1942:
1937:
1929:
1867:
1555:
1540:
1539:
1532:
1530:
1528:
1524:
1516:
1514:
1512:
1509:
1505:
1501:
1489:
1486:
1484:
1480:
1477:
1473:
1469:
1466:
1464:
1460:
1456:
1452:
1449:
1446:
1442:
1437:
1433:
1430:
1426:
1422:
1419:
1417:
1413:
1410:
1407:
1405:
1401:
1398:
1395:
1393:
1389:
1385:
1381:
1376:
1369:
1364:
1359:
1348:
1343:
1339:
1335:
1332:
1328:
1321:
1319:
1316:
1312:
1308:
1304:
1301:
1297:
1293:
1286:
1284:
1280:
1276:
1272:
1266:
1262:
1259:
1253:
1251:
1245:
1241:
1238:
1234:
1227:
1225:
1221:
1217:
1213:
1207:
1203:
1200:
1194:
1192:
1186:
1182:
1179:
1177:RefSeq (mRNA)
1175:
1168:
1167:
1162:
1158:
1155:
1149:
1148:
1143:
1139:
1136:
1134:
1130:
1123:
1122:
1117:
1113:
1110:
1104:
1103:
1098:
1094:
1091:
1089:
1085:
1078:
1077:
1072:
1068:
1065:
1059:
1058:
1053:
1049:
1046:
1044:
1040:
1037:
1034:
1032:
1029:
1025:
1022:
1018:
1014:
1007:
1003:
998:
992:
989:
987:
984:
982:
979:
977:
974:
972:
969:
967:
964:
962:
959:
957:
954:
952:
949:
947:
944:
942:
939:
937:
934:
932:
929:
927:
924:
922:
919:
917:
916:viral process
914:
912:
909:
907:
904:
902:
899:
897:
894:
892:
889:
887:
884:
882:
879:
877:
874:
872:
869:
867:
864:
862:
859:
857:
854:
852:
849:
847:
844:
842:
839:
837:
834:
832:
829:
827:
824:
822:
819:
817:
814:
812:
809:
807:
804:
802:
799:
797:
794:
792:
789:
787:
784:
782:
779:
777:
774:
773:
771:
768:
767:
761:
758:
756:
753:
751:
748:
746:
743:
741:
738:
736:
733:
731:
728:
726:
723:
721:
718:
716:
713:
711:
708:
707:
705:
702:
701:
695:
692:
690:
687:
685:
682:
680:
679:lipid binding
677:
675:
672:
670:
667:
665:
662:
660:
657:
655:
652:
650:
647:
645:
642:
640:
637:
635:
632:
630:
627:
625:
622:
620:
617:
616:
614:
611:
610:
607:
606:Gene ontology
603:
599:
587:
582:
578:
571:
566:
563:
561:
557:
549:
544:
533:
529:
525:
521:
517:
513:
509:
505:
501:
497:
496:
493:
489:
484:
481:
471:
467:
463:
459:
455:
451:
447:
443:
439:
435:
434:
431:
427:
422:
419:
418:
415:
413:
409:
407:
406:
402:
401:
398:
396:
392:
388:
384:
380:
372:
367:
363:
359:
354:
344:
340:
333:
326:
320:
313:
305:
301:
297:
292:
288:
283:
279:
271:
266:
262:
258:
253:
243:
239:
232:
225:
219:
212:
208:
202:
198:
194:
189:
185:
180:
176:
172:
168:
164:
160:
156:
152:
148:
144:
140:
136:
128:
123:
116:
111:
106:
95:
93:
89:
83:
78:
75:
74:
70:
67:
60:
56:
51:
47:
43:
38:
33:
30:
19:
3370:expanding it
3362:chromosome 1
3355:
3313:ATP-binding
3006:delivery of
2991:delivery of
2912:
2908:
2883:
2879:
2854:
2850:
2815:
2811:
2780:
2776:
2737:
2734:FEBS Letters
2733:
2704:
2700:
2673:
2669:
2620:
2616:
2590:(1): 43–51.
2587:
2583:
2553:(3): 283–5.
2550:
2546:
2507:
2466:
2462:
2423:
2419:
2388:
2384:
2356:(4): 822–7.
2353:
2349:
2315:(2): 79–88.
2312:
2308:
2275:
2271:
2244:
2240:
2215:
2209:
2172:
2168:
2158:
2144:
2111:
2107:
2097:
2070:
2066:
2056:
2047:
2038:
2029:
2020:
1951:
1537:
1536:
1520:
1517:Interactions
1507:
1499:
1498:
1279:NP_001292514
1275:NP_001292479
1271:NP_001292478
1268:
1247:
1224:NM_001305585
1220:NM_001305550
1216:NM_001305549
1209:
1188:
1164:
1145:
1119:
1100:
1074:
1055:
1035:
1030:
518:right kidney
410:
403:
369:171,053,948
356:171,052,623
268:161,223,631
255:161,222,292
130:External IDs
85:
29:
2997:Chylomicron
2981:Lipoprotein
2972:lipoprotein
2114:(1): 1–13.
1378:Identifiers
725:chylomicron
510:human fetus
460:granulocyte
108:Identifiers
3409:Categories
2707:(1): 1–7.
2015:, May 2017
1994:, May 2017
1970:References
1451:structures
526:blastocyst
414:(ortholog)
151:HomoloGene
3360:on human
2128:0021-9150
1409:IPR006801
1283:NP_038502
1250:NP_001634
1212:NM_013474
1191:NM_001643
1021:Orthologs
981:transport
159:GeneCards
2575:35574652
2337:31793659
2292:12642785
2263:11714842
2136:12119188
2011:–
1990:–
1523:interact
1468:RCSB PDB
1404:InterPro
1331:Wikidata
1000:Sources:
502:yolk sac
448:monocyte
444:testicle
3157:enzymes
2929:6433912
2900:6428397
2871:6407957
2842:6328445
2799:6315718
2764:9320651
2756:6090207
2721:6089788
2692:4344225
2657:4338591
2625:Bibcode
2604:3935800
2567:3136074
2538:3088392
2493:2995928
2450:2989800
2407:2414299
2372:2107739
2363:1683675
2329:1908160
2300:7365994
2191:9469594
2089:2415515
2013:Ensembl
1992:Ensembl
1547:[[File:
1504:protein
1397:PF04711
1386:ApoA-II
1361:ApoA-II
1133:UniProt
1088:Ensembl
1027:Species
1006:QuickGO
710:cytosol
389:pattern
115:Aliases
3303:LRPAP1
3222:SCARB1
3028:sd LDL
3025:lb LDL
2968:Lipids
2927:
2898:
2869:
2840:
2833:318799
2830:
2797:
2762:
2754:
2719:
2690:
2655:
2648:426687
2645:
2602:
2573:
2565:
2536:
2526:
2512:745–52
2491:
2484:321960
2481:
2448:
2441:321808
2438:
2405:
2370:
2360:
2335:
2327:
2298:
2290:
2261:
2207:Human
2189:
2134:
2126:
2087:
1483:PDBsum
1457:
1447:
1429:SUPFAM
1383:Symbol
1317:search
1315:PubMed
1166:P09813
1147:P02652
1043:Entrez
560:BioGPS
522:embryo
247:1q23.3
139:107670
3364:is a
3333:ABCG8
3328:ABCG5
3323:ABCA1
3296:LDL:
3290:LRP12
3285:LRP11
3280:LRP10
3265:LRP5L
3240:LRP1B
3228:IDL:
3220:HDL:
3098:APOC
3068:APOA
3032:Lp(a)
2760:S2CID
2571:S2CID
2333:S2CID
2296:S2CID
2216:APOA2
2210:APOA2
1859:]
1525:with
1508:APOA2
1502:is a
1425:SCOPe
1416:SCOP2
1076:11807
1036:Mouse
1031:Human
1002:Amigo
472:blood
452:gonad
412:Mouse
405:Human
352:Start
287:Mouse
251:Start
184:Human
163:APOA2
147:88050
122:APOA2
35:APOA2
18:APOA2
3366:stub
3358:gene
3298:LDLR
3275:LRP8
3270:LRP6
3260:LRP5
3255:LRP4
3250:LRP3
3245:LRP2
3235:LRP1
3203:PLTP
3198:MTTP
3193:CETP
3170:LIPC
3165:LCAT
3144:SAA1
3134:APOH
3129:APOE
3124:APOD
3094:APOB
3010:and
3002:VLDL
2925:PMID
2896:PMID
2867:PMID
2838:PMID
2795:PMID
2752:PMID
2717:PMID
2688:PMID
2653:PMID
2600:PMID
2563:PMID
2534:PMID
2524:ISBN
2489:PMID
2446:PMID
2403:PMID
2368:PMID
2325:PMID
2288:PMID
2259:PMID
2187:PMID
2132:PMID
2124:ISSN
2085:PMID
1941:edit
1928:edit
1511:gene
1476:PDBj
1472:PDBe
1455:ECOD
1445:Pfam
1421:1l6k
1392:Pfam
395:Bgee
343:Band
304:Chr.
242:Band
201:Chr.
155:1242
135:OMIM
92:2OU1
88:1L6L
69:RCSB
66:PDBe
3230:LRP
3175:LPL
3139:SAA
3037:HDL
3021:LDL
3016:IDL
2993:TGs
2917:doi
2913:122
2888:doi
2884:120
2859:doi
2855:364
2828:PMC
2820:doi
2785:doi
2781:258
2742:doi
2738:175
2709:doi
2705:123
2678:doi
2674:247
2643:PMC
2633:doi
2592:doi
2588:186
2555:doi
2516:doi
2479:PMC
2471:doi
2436:PMC
2428:doi
2393:doi
2389:260
2358:PMC
2317:doi
2313:419
2280:doi
2249:doi
2177:doi
2116:doi
2112:164
2075:doi
2071:260
1463:PDB
1057:336
365:End
264:End
167:OMA
143:MGI
59:PDB
3411::
3014::
3012:CE
2995::
2970::
2923:.
2911:.
2894:.
2882:.
2865:.
2853:.
2836:.
2826:.
2816:12
2814:.
2810:.
2793:.
2779:.
2775:.
2758:.
2750:.
2736:.
2732:.
2715:.
2703:.
2686:.
2672:.
2668:.
2651:.
2641:.
2631:.
2621:69
2619:.
2615:.
2598:.
2586:.
2569:.
2561:.
2551:79
2549:.
2532:.
2522:.
2514:.
2506:.
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2477:.
2467:13
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2434:.
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2418:.
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2366:.
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2257:.
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2171:.
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2130:.
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2110:.
2106:.
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2028:.
1999:^
1978:^
1930:]]
1529:.
1474:;
1470:;
1453:/
1427:/
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1004:/
371:bp
358:bp
270:bp
257:bp
165:;
161::
157:;
153::
149:;
145::
141:;
137::
90:,
3397:e
3390:t
3383:v
3372:.
3117:4
3112:3
3107:2
3102:1
3087:5
3082:4
3077:2
3072:1
3008:C
2960:e
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2931:.
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2890::
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289:)
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169::
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