219:
1302:
29:
414:
384:
Aceperone has been used as a tool in the study of the biochemical basis of learning. Although aceperone does not block learning per se, it blocks access to an attentional mechanism by which animals ‘tune in’ to the relevant visual dimension when learning a visual discrimination task at doses below
471:
Baker HF, Ridley RM, Haystead TA, Crow TJ (May 1983). "Further consideration of the learning impairment after aceperone in the marmoset: effects of the drug on shape and colour discrimination and on an alternation task".
428:
Ridley RM, Haystead TA, Baker HF, Crow TJ (June 1981). "A new approach to the role of noradrenaline in learning: problem-solving in the marmoset after alpha-noradrenergic receptor blockade".
49:
1347:
319:
295:
347:
InChI=1S/C24H29FN2O2/c1-19(28)26-18-24(21-6-3-2-4-7-21)13-16-27(17-14-24)15-5-8-23(29)20-9-11-22(25)12-10-20/h2-4,6-7,9-12H,5,8,13-18H2,1H3,(H,26,28)
576:
1366:
1340:
1376:
1261:
515:
Scraggs PR, Ridley RM (March 1979). "The effect of dopamine and noradrenaline blockade on amphetamine-induced behaviour in the marmoset".
1396:
1381:
1333:
339:
1391:
73:
1386:
569:
158:
1278:
198:
1222:
412:, "Alkoxylamino and alkoxycarbonylamino derivatives of 1(aroylalkyl)-4-arylpiperidines.", published 1961
910:
811:
1266:
674:
562:
1174:
1078:
1045:
1025:
905:
876:
789:
784:
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187:
1130:
888:
806:
639:
622:
598:
378:
405:
214:
1371:
1309:
374:
93:
540:
497:
453:
532:
489:
445:
1317:
1116:
818:
524:
481:
437:
235:
1301:
167:
147:
1058:
866:
853:
848:
838:
754:
218:
102:
1313:
1272:
900:
796:
722:
707:
1360:
1237:
1142:
1137:
1103:
1054:
977:
939:
833:
828:
697:
666:
607:
585:
485:
441:
370:
306:
544:
457:
1200:
1125:
1108:
1073:
1000:
995:
871:
861:
843:
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702:
679:
589:
501:
409:
127:
1247:
1195:
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1120:
1095:
1090:
1085:
1063:
1020:
1005:
969:
949:
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934:
883:
801:
769:
727:
717:
684:
651:
634:
617:
366:
1227:
1205:
1180:
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1010:
959:
732:
661:
629:
612:
271:
138:
1232:
1165:
1160:
1155:
1035:
990:
982:
954:
929:
895:
823:
656:
493:
449:
20:
1185:
1015:
964:
764:
689:
646:
536:
554:
779:
528:
113:
28:
178:
294:
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558:
203:
1321:
1214:
1044:
921:
597:
305:
283:
270:
234:
229:
197:
177:
157:
137:
112:
92:
64:
48:
40:
35:
126:
327:Fc1ccc(cc1)C(=O)CCCN3CCC(c2ccccc2)(CC3)CNC(=O)C
101:
1341:
570:
84:-({1--4-phenyl-4-piperidinyl}methyl)acetamide
8:
19:
1348:
1334:
577:
563:
555:
217:
146:
400:
398:
166:
474:Pharmacology, Biochemistry, and Behavior
430:Pharmacology, Biochemistry, and Behavior
394:
344:
324:
311:97 to 100 °C (207 to 212 °F)
213:
78:
18:
385:those that affect general behaviour.
186:
7:
1298:
1296:
755:Levomepromazine (methotrimeprazine)
117:
1320:. You can help Knowledge (XXG) by
14:
1300:
255:
252:
246:
27:
352:Key:VDGZERMDPAAZEJ-UHFFFAOYSA-N
1367:Drugs not assigned an ATC code
261:
240:
1:
1377:Butyrophenone antipsychotics
486:10.1016/0091-3057(83)90009-6
442:10.1016/0091-3057(81)90373-7
377:blocking drug developed by
1413:
1295:
1223:Monoamine-depleting agents
718:Carphenazine (carfenazine)
230:Chemical and physical data
1397:Nervous system drug stubs
1256:
335:
315:
69:
26:
1382:4-Fluorophenyl compounds
1312:article relating to the
911:Zuclopenthixol decanoate
812:Pipotiazine undecylenate
675:Diphenylbutylpiperidines
896:Tiotixene (thiothixene)
1392:Typical antipsychotics
1079:Paliperidone palmitate
1026:Oxyprothepin decanoate
906:Zuclopenthixol acetate
877:Clopenthixol decanoate
790:Perphenazine enanthate
785:Perphenazine decanoate
748:Fluphenazine enanthate
743:Fluphenazine decanoate
1131:Aripiprazole lauroxil
889:Flupentixol decanoate
807:Pipotiazine palmitate
640:Haloperidol decanoate
623:Bromperidol decanoate
379:Janssen Pharmaceutica
1387:4-Phenylpiperidines
23:
1283:Never to phase III
529:10.1007/BF00426033
517:Psychopharmacology
44:Acetabuton; R 3248
1329:
1328:
1293:
1292:
1117:Phenylpiperazines
373:class. It is an
360:
359:
296:Interactive image
199:CompTox Dashboard
16:Chemical compound
1404:
1350:
1343:
1336:
1304:
1297:
1059:benzisothiazoles
819:Prochlorperazine
579:
572:
565:
556:
549:
548:
512:
506:
505:
468:
462:
461:
425:
419:
418:
417:
413:
402:
298:
278:
263:
257:
254:
248:
242:
222:
221:
207:
205:
190:
170:
150:
130:
120:
119:
105:
31:
24:
22:
1412:
1411:
1407:
1406:
1405:
1403:
1402:
1401:
1357:
1356:
1355:
1354:
1294:
1289:
1288:
1273:Clinical trials
1252:
1245:Others/unknown:
1210:
1040:
917:
867:Chlorprothixene
854:Triflupromazine
849:Trifluoperazine
839:Thioproperazine
593:
583:
553:
552:
514:
513:
509:
470:
469:
465:
427:
426:
422:
415:
404:
403:
396:
391:
375:α-noradrenergic
356:
353:
348:
343:
342:
331:
328:
323:
322:
301:
276:
266:
260:
251:
245:
225:
201:
193:
173:
153:
133:
116:
108:
88:
85:
77:
76:
60:
17:
12:
11:
5:
1410:
1408:
1400:
1399:
1394:
1389:
1384:
1379:
1374:
1369:
1359:
1358:
1353:
1352:
1345:
1338:
1330:
1327:
1326:
1314:nervous system
1305:
1291:
1290:
1287:
1286:
1285:
1284:
1281:
1270:
1264:
1258:
1257:
1254:
1253:
1251:
1250:
1241:
1240:
1235:
1230:
1218:
1216:
1212:
1211:
1209:
1208:
1203:
1198:
1189:
1188:
1183:
1178:
1168:
1163:
1151:
1150:
1145:
1140:
1135:
1134:
1133:
1112:
1111:
1104:Butyrophenones
1099:
1098:
1093:
1088:
1083:
1082:
1081:
1071:
1066:
1050:
1048:
1042:
1041:
1039:
1038:
1029:
1028:
1023:
1018:
1013:
1008:
1003:
998:
986:
985:
978:Butyrophenones
973:
972:
967:
962:
957:
952:
947:
942:
937:
925:
923:
919:
918:
916:
915:
914:
913:
908:
901:Zuclopenthixol
898:
893:
892:
891:
881:
880:
879:
869:
857:
856:
851:
846:
841:
836:
831:
826:
821:
816:
815:
814:
809:
799:
797:Piperacetazine
794:
793:
792:
787:
782:
772:
767:
762:
757:
752:
751:
750:
745:
735:
730:
725:
723:Chlorpromazine
720:
715:
710:
708:Acetophenazine
705:
698:Phenothiazines
693:
692:
687:
682:
670:
669:
664:
659:
654:
649:
644:
643:
642:
632:
627:
626:
625:
615:
608:Butyrophenones
603:
601:
595:
594:
586:Antipsychotics
584:
582:
581:
574:
567:
559:
551:
550:
507:
463:
420:
393:
392:
390:
387:
381:in the 1960s.
358:
357:
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351:
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338:
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336:
333:
332:
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318:
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309:
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274:
268:
267:
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258:
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226:
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215:DTXSID30230510
210:
208:
195:
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192:
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183:
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175:
174:
172:
171:
163:
161:
155:
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143:
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135:
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131:
123:
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110:
109:
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72:
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62:
61:
59:
58:
54:
52:
46:
45:
42:
38:
37:
33:
32:
15:
13:
10:
9:
6:
4:
3:
2:
1409:
1398:
1395:
1393:
1390:
1388:
1385:
1383:
1380:
1378:
1375:
1373:
1370:
1368:
1365:
1364:
1362:
1351:
1346:
1344:
1339:
1337:
1332:
1331:
1325:
1323:
1319:
1315:
1311:
1306:
1303:
1299:
1282:
1280:
1277:
1276:
1274:
1271:
1268:
1265:
1263:
1260:
1259:
1255:
1249:
1246:
1243:
1242:
1239:
1238:Tetrabenazine
1236:
1234:
1231:
1229:
1226:
1224:
1220:
1219:
1217:
1213:
1207:
1204:
1202:
1199:
1197:
1194:
1191:
1190:
1187:
1184:
1182:
1179:
1176:
1172:
1169:
1167:
1164:
1162:
1159:
1157:
1153:
1152:
1149:
1146:
1144:
1143:Brexpiprazole
1141:
1139:
1138:Brilaroxazine
1136:
1132:
1129:
1128:
1127:
1124:
1122:
1118:
1114:
1113:
1110:
1107:
1105:
1101:
1100:
1097:
1094:
1092:
1089:
1087:
1084:
1080:
1077:
1076:
1075:
1072:
1070:
1067:
1065:
1062:
1060:
1056:
1055:Benzisoxazole
1052:
1051:
1049:
1047:
1043:
1037:
1034:
1031:
1030:
1027:
1024:
1022:
1019:
1017:
1014:
1012:
1009:
1007:
1004:
1002:
999:
997:
994:
992:
988:
987:
984:
981:
979:
975:
974:
971:
968:
966:
963:
961:
958:
956:
953:
951:
948:
946:
943:
941:
940:Levosulpiride
938:
936:
933:
931:
927:
926:
924:
920:
912:
909:
907:
904:
903:
902:
899:
897:
894:
890:
887:
886:
885:
882:
878:
875:
874:
873:
870:
868:
865:
863:
862:Thioxanthenes
859:
858:
855:
852:
850:
847:
845:
842:
840:
837:
835:
834:Thiopropazate
832:
830:
829:Sulforidazine
827:
825:
822:
820:
817:
813:
810:
808:
805:
804:
803:
800:
798:
795:
791:
788:
786:
783:
781:
778:
777:
776:
773:
771:
768:
766:
763:
761:
758:
756:
753:
749:
746:
744:
741:
740:
739:
736:
734:
731:
729:
726:
724:
721:
719:
716:
714:
711:
709:
706:
704:
701:
699:
695:
694:
691:
688:
686:
683:
681:
678:
676:
672:
671:
668:
667:Trifluperidol
665:
663:
660:
658:
655:
653:
650:
648:
645:
641:
638:
637:
636:
633:
631:
628:
624:
621:
620:
619:
616:
614:
611:
609:
605:
604:
602:
600:
596:
591:
587:
580:
575:
573:
568:
566:
561:
560:
557:
546:
542:
538:
534:
530:
526:
522:
518:
511:
508:
503:
499:
495:
491:
487:
483:
479:
475:
467:
464:
459:
455:
451:
447:
443:
439:
436:(6): 849–55.
435:
431:
424:
421:
411:
407:
401:
399:
395:
388:
386:
382:
380:
376:
372:
371:butyrophenone
368:
364:
350:
345:
341:
334:
325:
321:
314:
310:
308:
307:Melting point
304:
297:
293:
292:
290:
287:
282:
275:
273:
269:
239:
237:
233:
228:
220:
216:
212:
211:
209:
200:
196:
189:
185:
184:
182:
180:
176:
169:
165:
164:
162:
160:
156:
149:
145:
144:
142:
140:
136:
129:
125:
124:
122:
115:
111:
104:
100:
99:
97:
95:
91:
83:
79:
75:
68:
63:
56:
55:
53:
51:
47:
43:
39:
36:Clinical data
34:
30:
25:
1322:expanding it
1307:
1244:
1221:
1201:Pimavanserin
1192:
1175:+samidorphan
1154:
1126:Aripiprazole
1121:quinolinones
1115:
1109:Lumateperone
1102:
1074:Paliperidone
1053:
1032:
1001:Clocapramine
996:Carpipramine
989:
976:
928:
872:Clopenthixol
860:
844:Thioridazine
775:Perphenazine
760:Mesoridazine
738:Fluphenazine
713:Butaperazine
703:Acepromazine
696:
680:Fluspirilene
673:
606:
520:
516:
510:
480:(5): 701–4.
477:
473:
466:
433:
429:
423:
383:
369:drug of the
362:
361:
188:ChEMBL136298
81:
1269:from market
1248:Azacyclonol
1196:Blonanserin
1148:Cariprazine
1096:Ziprasidone
1091:Risperidone
1086:Perospirone
1064:Iloperidone
1021:Mosapramine
1006:Clorotepine
970:Veralipride
950:Remoxipride
945:Nemonapride
935:Amisulpride
884:Flupentixol
802:Pipotiazine
770:Periciazine
728:Cyamemazine
685:Penfluridol
652:Pipamperone
635:Haloperidol
618:Bromperidol
523:(1): 41–5.
367:neuroleptic
279: g·mol
65:Identifiers
41:Other names
1372:Acetamides
1361:Categories
1228:Oxypertine
1206:Sertindole
1181:Quetiapine
1171:Olanzapine
1156:Tricyclics
1069:Lurasidone
1011:Clotiapine
991:Tricyclics
960:Sultopride
930:Benzamides
733:Dixyrazine
662:Timiperone
630:Droperidol
613:Benperidol
410:Janssen PA
389:References
284:3D model (
272:Molar mass
168:S69KXZ59AB
139:ChemSpider
94:CAS Number
74:IUPAC name
1279:Phase III
1267:Withdrawn
1233:Reserpine
1166:Clozapine
1161:Asenapine
1036:Molindone
983:Melperone
955:Sulpiride
824:Promazine
657:Spiperone
406:BE 606849
363:Aceperone
21:Aceperone
1186:Zotepine
1046:Atypical
1016:Loxapine
965:Tiapride
922:Disputed
765:Perazine
690:Pimozide
647:Moperone
545:38197514
458:35341802
103:807-31-8
50:ATC code
1193:Others:
1033:Others:
780:BL-1020
599:Typical
502:7905046
494:6222386
450:6114497
277:396.506
236:Formula
114:PubChem
1262:WHO-EM
1215:Others
543:
537:155838
535:
500:
492:
456:
448:
416:
408:,
320:SMILES
179:ChEMBL
1316:is a
1308:This
541:S2CID
498:S2CID
454:S2CID
365:is a
340:InChI
286:JSmol
148:12570
128:13122
1318:stub
1310:drug
590:N05A
533:PMID
490:PMID
446:PMID
159:UNII
57:none
525:doi
482:doi
438:doi
204:EPA
118:CID
1363::
1275::
539:.
531:.
521:62
519:.
496:.
488:.
478:18
476:.
452:.
444:.
434:14
432:.
397:^
250:29
244:24
1349:e
1342:t
1335:v
1324:.
1225::
1177:)
1173:(
1158::
1123::
1119:/
1106::
1061::
1057:/
993::
980::
932::
864::
700::
677::
610::
592:)
588:(
578:e
571:t
564:v
547:.
527::
504:.
484::
460:.
440::
288:)
265:2
262:O
259:2
256:N
253:F
247:H
241:C
206:)
202:(
82:N
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
