61:
37:
106:. The lesions range in hue from brown to skin tone, and their friction might cause vesicles. The backs of the hands and feet's proximal and distal interphalangeal joints are typically where the lesions are seen. Lesions are less common and only occasionally seen on other body parts. The frontal scalp, flexures, and
85:
resembling warts along with palmoplantar punctate keratoses and pits. However sporadic forms, whose less than 10 cases have been reported, presents at a later age, usually after the first decade and generally lack palmoplantar keratoses. Whether acrokeratosis verruciformis and Darier disease are
826:
811:
731:
Bergman, Reuven; Sezin, Tanya; Indelman, Margarita; Helou, Wissam Abo; Avitan-Hersh, Emily (2012). "Acrokeratosis
Verruciformis of Hopf Showing P602L Mutation in ATP2A2 and Overlapping Histopathological Features With Darier Disease".
630:
Wang, P.-G.; Gao, M.; Lin, G.-S.; Yang, S.; Lin, D.; Liang, Y.-H.; Zhang, G.-L.; Zhu, Y.-G.; Cui, Y.; Zhang, K.-Y.; Huang, W.; Zhang, X.-J. (2006). "Genetic heterogeneity in acrokeratosis verruciformis of Hopf".
373:
Andrade, Tatiana
Cristina Pedro Cordeiro de; Silva, GardĂŞnia Viana da; Silva, Tatiane Meira Pinho; Pinto, Ana CecĂlia Versiani Duarte; Nunes, Adauto JosĂ© Ferreira; Martelli, AntĂ´nio Carlos Ceribelli (2016).
180:
946:
686:
Farro, P.; Zalaudek, I.; Ferrara, G.; Fulgione, E.; Cicale, L.; Petrillo, G.; Zanchini, R.; Ruocco, E.; Argenziano, G. (2004-05-26). "Fallberichte".
111:
604:
Ormond, Débora Teresa da Silva; Viana, Silvânia
Saraiva; Vitral, Érica A. O; Pereira, Carlos Adolpho C; Carvalho, Maria Teresa Feital de (1998).
259:
234:
209:
992:
980:
841:
94:
gene. however the specific mutations found in the ATP2A2 gene in acrokeratosis verruciformis have never been found in Darier's disease.
431:
Serarslan, Gamze; Di˙dar Balci, Di˙dem; Homan, Seydo (2007-01-01). "Acitretin treatment in acrokeratosis verruciformis of Hopf".
939:
175:
280:"Acrokeratosis verruciformis of Hopf is caused by mutation in ATP2A2: evidence that it is allelic to Darier's disease"
1043:
932:
1101:
1151:
1073:
903:
497:(Suppl 1). Korean Dermatological Association and The Korean Society for Investigative Dermatology: S61-3.
321:"Whole-exome sequencing solves diagnostic dilemma in a rare case of sporadic acrokeratosis verruciformis"
820:
278:
Dhitavat J, Macfarlane S, Dode L, Leslie N, Sakuntabhai A, MacSween R, et al. (February 2003).
60:
1078:
1027:
783:
87:
765:
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464:
350:
74:
924:
114:
is another symptom of the illness. Changes to the nails, such as thickening of the nail plate,
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49:
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Gupta A, Sharma YK, Vellarikkal SK, Jayarajan R, Dixit V, Verma A, et al. (April 2016).
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Bang, Chul Hwan; Kim, Hei Sung; Park, Young Min; Kim, Hyung Ok; Lee, Jun Young (2011).
408:
375:
155:
143:
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699:
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151:
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Clinical signs of acrokeratosis include verrucous plaques and flat-topped, polygonal
769:
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468:
354:
391:
745:
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115:
107:
78:
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Superficial ablation is currently the only effective treatment available.
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444:
139:
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707:
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510:
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Acrokeratosis verruciformis has an autosomal dominant pattern of inheritance
761:
715:
660:
590:
528:
460:
417:
346:
305:
898:
158:, which are limited epidermal elevations referred to as "church spires."
803:
225:
Freedberg IM, Eisen IZ, Wolff K, Austen F, Goldsmith LA, Katz S (2003).
1096:
337:
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987:
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959:
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The diagnosis is established by histological characteristics such as
127:
118:, longitudinal ridges, and nicks in the free edges, are often noted.
103:
91:
82:
912:
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disorder appearing at birth or in early childhood, characterized by
1061:
868:
846:
928:
325:
Journal of the
European Academy of Dermatology and Venereology
229:(6th ed.). New York: McGraw-Hill, Medical Pub. Division.
547:"Acrokeratosis verruciformis of hopf along lines of blaschko"
110:
are not affected by the condition. On the palms and soles,
126:
Acrokeratosis verruciformis is caused by mutations in the
86:
related or distinct entities has been controversial, like
740:(6). Ovid Technologies (Wolters Kluwer Health): 597–601.
688:
JDDG: Journal der
Deutschen Dermatologischen Gesellschaft
252:
376:"Acrokeratosis verruciformis of Hopf — Case report"
130:
gene and is inherited in an autosomal dominant fashion.
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1111:
1088:
1053:
1002:
967:
878:
797:
606:"Acroceratose verruciforme de Hopf: relato de caso"
540:
538:
48:
26:
21:
487:"Non-familial Acrokeratosis Verruciformis of Hopf"
254:(10th ed.). Philadelphia: Saunders Elsevier.
480:
478:
273:
271:
940:
639:(4). Oxford University Press (OUP): 558–563.
368:
366:
364:
227:Fitzpatrick's Dermatology in General Medicine
181:List of genes mutated in cutaneous conditions
8:
200:Rapini RP, Bolognia JL, Jorizzo JL (2007).
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18:
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734:The American Journal of Dermatopathology
284:The Journal of Investigative Dermatology
192:
90:, it is associated with defects in the
297:10.1046/j.1523-1747.2003.t01-1-12045.x
633:Clinical and Experimental Dermatology
250:James WD, Berger T, Elston D (2006).
7:
993:Alternating hemiplegia of childhood
981:Alternating hemiplegia of childhood
433:Journal of Dermatological Treatment
386:(5). FapUNIFESP (SciELO): 639–641.
30:Acrokeratosis verruciformis of Hopf
439:(2). Informa UK Limited: 123–125.
14:
380:Anais Brasileiros de Dermatologia
700:10.1046/j.1439-0353.2004.04776.x
645:10.1111/j.1365-2230.2006.02134.x
81:that are small, verrucous, flat
1:
551:Indian Journal of Dermatology
392:10.1590/abd1806-4841.20164919
746:10.1097/dad.0b013e31823f9194
176:List of cutaneous conditions
1032:Acrokeratosis verruciformis
71:Acrokeratosis verruciformis
22:Acrokeratosis verruciformis
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503:10.5021/ad.2011.23.s1.s61
445:10.1080/09546630601121029
202:Dermatology: 2-Volume Set
43:
34:
564:10.4103/0019-5154.117324
545:Nair, PragyaA (2013).
1044:Hailey–Hailey disease
694:(6). Wiley: 440–447.
612:(in Portuguese): 25–7
491:Annals of Dermatology
1102:Kufor–Rakeb syndrome
204:. St. Louis: Mosby.
557:(5). Medknow: 406.
879:External resources
610:An. Bras. Dermatol
112:punctate keratosis
98:Signs and symptoms
75:autosomal dominant
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338:10.1111/jdv.12983
261:978-0-7216-2921-6
236:978-0-07-138076-8
211:978-1-4160-2999-1
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16:Medical condition
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1119:Osteopetrosis B1
1079:Wilson's disease
1028:Darier's disease
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1016:Brody myopathy
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79:skin lesions
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116:leukonychia
108:oral mucosa
27:Other names
853:DiseasesDB
789:StatPearls
616:2024-02-26
187:References
140:acanthosis
73:is a rare
1130:see also
962:disorders
888:eMedicine
869:400085009
864:SNOMED CT
754:0193-1091
708:1610-0379
653:0307-6938
573:0019-5154
511:1013-9087
453:0954-6634
400:0365-0596
162:Treatment
134:Diagnosis
50:Specialty
1146:Category
913:Q4675784
899:Orphanet
770:21488408
762:22814319
724:28306714
716:16281601
669:29529897
661:16716163
591:24082200
529:22028575
469:21336730
461:17520472
418:27828639
355:35181817
347:25622760
306:12542527
170:See also
150:without
1097:ATP13A2
909:Scholia
784:DermNet
582:3778795
520:3199425
409:5087224
104:papules
83:papules
1132:ATPase
1039:ATP2C1
1023:ATP2A2
1011:ATP2A1
988:ATP1A3
976:ATP1A2
960:ATPase
847:101900
821:EC20.Y
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154:, and
128:ATP2A2
122:Causes
92:ATP2A2
57:
1112:Other
1089:ATP13
1074:ATP7B
1062:ATP7A
904:79151
836:Q82.8
766:S2CID
720:S2CID
665:S2CID
465:S2CID
351:S2CID
1054:ATP7
1003:ATP2
968:ATP1
858:3467
842:OMIM
758:PMID
750:ISSN
712:PMID
704:ISSN
657:PMID
649:ISSN
587:PMID
569:ISSN
525:PMID
507:ISSN
457:PMID
449:ISSN
414:PMID
396:ISSN
343:PMID
302:PMID
256:ISBN
231:ISBN
206:ISBN
827:ICD
812:ICD
742:doi
696:doi
641:doi
577:PMC
559:doi
515:PMC
499:doi
441:doi
404:PMC
388:doi
333:doi
292:doi
288:120
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384:91
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329:30
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