Knowledge

Alison R. H. Narayan

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BenĂ­tez, Attabey RodrĂ­guez; Tweedy, Sara; Dockrey, Summer A. Baker; Lukowski, April L.; Wymore, Troy; Khare, Dheeraj; Brooks L. Charles III; Smith Janet L.; Narayan Alison R.H. (2018): Structural Basis for Selectivity in Flavin-Dependent Monooxygenase-Catalyzed Oxidative Dearomatization. ChemRxiv.
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Narayan, Alison R. H.; Jiménez-Osés, Gonzalo; Liu, Peng; Negretti, Solymar; Zhao, Wanxiang; Gilbert, Michael M.; Ramabhadran, Raghunath O.; Yang, Yun-Fang; Furan, Lawrence R.; Li, Zhe; Podust, Larissa M. (2015).
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Negretti, Solymar; Narayan, Alison R. H.; Chiou, Karoline C.; Kells, Petrea M.; Stachowski, Jessica L.; Hansen, Douglas A.; Podust, Larissa M.; Montgomery, John; Sherman, David H. (2014-04-02).
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The Narayan lab focuses on identifying and characterizing enzymes from various microorganisms that can catalyze chemical reactions that are challenging to reproduce synthetically. These
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Sherman, David H.; Houk, K. N.; Montgomery, John; Podust, Larissa M.; Li, Zhe; Furan, Lawrence R.; Yun-Fang Yang; Ramabhadran, Raghunath O.; Gilbert, Michael M. (August 2015).
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Lukowski, A. L.; Ellinwood, D. C.; Hinze, M. E.; DeLuca, R. J.; Du Bois, J.; Hall, S.; Narayan, A. R. H. "C–H hydroxylation in paralytic shellfish toxin biosynthesis"
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Baker Dockrey, S. A.; Doyon, T. J.; Perkins, J. C.; Narayan, A. R. H. “Whole-cell biocatalysis platform for gram-scale oxidative dearomatization of phenols”
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Baker Dockrey, S. A.; Lukowski, A. L.; Becker, M. R.; Narayan, A. R. H. “Biocatalytic site- and enantioselective oxidative dearomatization of phenols”
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Lukowski, A. L.. and Narayan, A. R. H. “Natural voltage-gated sodium channel ligands: Biosynthesis and biology”
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Chun, S. W.; Hinze, M. E.; Skiba, M. A.; Narayan, A. R. H. "Chemistry of a unique polyketide-like synthase"
267: 231: 167: 100: 1206: 662:"Indolizinones as synthetic scaffolds: fundamental reactivity and the relay of stereochemical information" 215: 191: 160: 96: 51: 442:“Enzymatic Hydroxylation of an Unactivated Methylene C–H Bond Guided by Molecular Dynamics Simulations” ( 897: 294: 187: 1073:"Enzymatic hydroxylation of an unactivated methylene C–H bond guided by molecular dynamics simulations" 1046: 834:"Enzymatic hydroxylation of an unactivated methylene C–H bond guided by molecular dynamics simulations" 636: 140: 1181: 1084: 933: 845: 179: 614:
New Reactions and Synthetic Strategies toward Indolizidine Alkaloids and Pallavicinia Diterpenes
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New Reactions and Synthetic Strategies toward Indolizidine Alkaloids and Pallavicinia Diterpenes
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New Reactions and Synthetic Strategies toward Indolizidine Alkaloids and Pallavicinia Diterpenes
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in 2006. During her bachelor's degree, she carried out research under the supervision of
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Baker Dockrey, S. A. and Narayan, A. R. H. “Flavin-dependent biocatalysts in synthesis”
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in non-native substrates. In 2015, Narayan joined the Department of Chemistry and the
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and the William R. Roush assistant professor in the Department of Chemistry at the
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can be employed to create various chemicals for pharmaceutical or other purposes.
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University of Michigan College of Literature, Science, and the Arts alumni
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rings. Narayan completed her Ph.D. in organic chemistry in 2011 with
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on palladium-catalyzed methodology for the synthesis of substituted
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Sarpong, Richmond; Narayan, Alison R. Hardin (2012-01-07).
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Hay, Michael B.; Hardin, Alison R.; Wolfe, John P. (2005).
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Narayan has received numerous awards and honors including:
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at the University of Michigan as an assistant professor.
970:"2019 Awardees - Thieme Chemistry - Georg Thieme Verlag" 309:(Special Issue on Biocatalysis in Organic Synthesis). 487:"Alison Rae-Hardin Narayan from Ann Arbor, Michigan" 136: 124: 106: 92: 78: 44: 36: 28: 21: 633:Synthetic organic chemistry lab at UC Berkeley 1047:"2020 Camille Dreyfus Teacher-Scholar Awards" 994:"RCSA Names Two Dozen 2019 Cottrell Scholars" 190:. She completed her B.S. in chemistry at the 8: 998:Research Corporation for Science Advancement 164:College of Literature, Science, and the Arts 535:. University of Michigan. 21 February 2018 18: 1197:University of California, Berkeley alumni 1112: 945: 873: 807: 693: 587: 780:Journal of the American Chemical Society 222:lab. During her postdoc, she engineered 1158:Life Sciences Institute faculty profile 1153:Department of Chemistry faculty profile 898:"A year in the life of a new professor" 478: 264:Thieme Chemistry Journals Award (2019) 1227:21st-century American women scientists 769: 767: 280:Camille Dreyfus Teacher-Scholar Award 7: 741: 739: 737: 666:Organic & Biomolecular Chemistry 655: 653: 214:". In 2011, Narayan returned to the 922:"How bacteria build a deadly toxin" 611:Narayan, Alison Rae Hardin (2011). 208:University of California, Berkeley 60:University of California, Berkeley 14: 1139:Chemical Biology faculty profile 560:The Journal of Organic Chemistry 168:Michigan Life Sciences Institute 639:from the original on 2020-03-31 186:graduating from high school in 1202:21st-century American chemists 1187:University of Michigan faculty 469:2012, DOI: 10.1039/clob06423a) 459:2014, DOI: 10.1021/ja5016052) 449:2015, DOI: 10.1038/nchem.2285) 1: 261:C&EN, Talented 12 (2016) 16:American chemist (born 1984) 629:"The Sarpong Group Homepage" 342:10.26434/chemrxiv.7297766.v1 218:as a postdoctoral fellow in 137:Other academic advisors 32:1984 (age 39–40) 330:(Special Issue: New Talent) 155:(born 1984) is an American 1248: 947:10.1038/d41586-018-02199-4 210:, with a thesis entitled " 1217:American women scientists 932:(7693): 407. 2018-02-19. 437:Mentored Key Publications 306:10.1016/j.tet.2019.01.008 259:American Chemical Society 153:Alison Rae Hardin Narayan 146: 71: 1222:American women academics 1165:publications indexed by 747:"C&EN's Talented 12" 513:. University of Michigan 174:Early life and education 232:Life Sciences Institute 224:cytochrome P450 enzymes 101:Life Sciences Institute 1232:Chemists from Michigan 1212:Sloan Research Fellows 617:(Thesis). UC Berkeley. 327:10.1002/cbic.201800754 216:University of Michigan 192:University of Michigan 161:University of Michigan 97:University of Michigan 52:University of Michigan 348:Chem. Biol. Drug Des. 274:Sloan Research Fellow 228:C-H functionalization 1163:Alison R. H. Narayan 533:"Alison Narayan Lab" 407:10.1021/jacs.7b13297 383:10.1021/jacs.8b08901 1089:2015NatCh...7..653N 938:2018Natur.554U.407. 850:2015NatCh...7..653N 178:Narayan grew up in 23:Alison R.H. Narayan 1097:10.1038/nchem.2285 1051:Dreyfus Foundation 858:10.1038/nchem.2285 678:10.1039/C1OB06423A 431:10.1038/nchem.2879 377:(37), 11863–11869 358:10.1111/cbdd.13443 792:10.1021/ja5016052 786:(13): 4901–4904. 572:10.1021/jo050022+ 465:Org. Biomol. Chem 268:Cottrell Scholars 250:Awards and honors 150: 149: 87:Organic chemistry 73:Scientific career 1239: 1149: 1148: 1146:Official website 1127: 1126: 1116: 1077:Nature Chemistry 1068: 1062: 1061: 1059: 1058: 1043: 1037: 1036: 1034: 1033: 1024:. Archived from 1014: 1008: 1007: 1005: 1004: 990: 984: 983: 981: 980: 966: 960: 959: 949: 918: 912: 911: 909: 908: 894: 888: 887: 877: 838:Nature Chemistry 828: 822: 821: 811: 771: 762: 761: 759: 758: 743: 732: 731: 729: 728: 714: 708: 707: 697: 657: 648: 647: 645: 644: 625: 619: 618: 608: 602: 601: 591: 566:(8): 3099–3107. 551: 545: 544: 542: 540: 529: 523: 522: 520: 518: 511:"Alison Narayan" 507: 501: 500: 498: 497: 491:voterrecords.com 483: 455:J. Am. Chem. Soc 390:J. Am. Chem. Soc 365:J. Am. Chem. Soc 287:Key publications 204:Richmond Sarpong 141:David H. Sherman 131:Richmond Sarpong 126:Doctoral advisor 120: 64: 56: 19: 1247: 1246: 1242: 1241: 1240: 1238: 1237: 1236: 1172: 1171: 1144: 1143: 1135: 1130: 1070: 1069: 1065: 1056: 1054: 1045: 1044: 1040: 1031: 1029: 1016: 1015: 1011: 1002: 1000: 992: 991: 987: 978: 976: 968: 967: 963: 920: 919: 915: 906: 904: 896: 895: 891: 830: 829: 825: 773: 772: 765: 756: 754: 745: 744: 735: 726: 724: 716: 715: 711: 659: 658: 651: 642: 640: 627: 626: 622: 610: 609: 605: 553: 552: 548: 538: 536: 531: 530: 526: 516: 514: 509: 508: 504: 495: 493: 485: 484: 480: 476: 289: 252: 240: 220:David Sherman's 200:tetrahydrofuran 176: 118: 67: 62: 54: 45:Alma mater 24: 17: 12: 11: 5: 1245: 1243: 1235: 1234: 1229: 1224: 1219: 1214: 1209: 1204: 1199: 1194: 1189: 1184: 1174: 1173: 1170: 1169: 1167:Google Scholar 1160: 1155: 1150: 1141: 1134: 1133:External links 1131: 1129: 1128: 1083:(8): 653–660. 1063: 1038: 1018:"2019 Fellows" 1009: 985: 961: 913: 889: 844:(8): 653–660. 823: 763: 733: 709: 649: 620: 603: 546: 524: 502: 477: 475: 472: 471: 470: 460: 450: 434: 433: 409: 385: 360: 344: 333: 311: 288: 285: 284: 283: 277: 271: 265: 262: 251: 248: 239: 236: 175: 172: 148: 147: 144: 143: 138: 134: 133: 128: 122: 121: 110: 104: 103: 94: 90: 89: 80: 76: 75: 69: 68: 66: 65: 57: 48: 46: 42: 41: 38: 34: 33: 30: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 1244: 1233: 1230: 1228: 1225: 1223: 1220: 1218: 1215: 1213: 1210: 1208: 1207:Living people 1205: 1203: 1200: 1198: 1195: 1193: 1190: 1188: 1185: 1183: 1180: 1179: 1177: 1168: 1164: 1161: 1159: 1156: 1154: 1151: 1147: 1142: 1140: 1137: 1136: 1132: 1124: 1120: 1115: 1110: 1106: 1102: 1098: 1094: 1090: 1086: 1082: 1078: 1074: 1067: 1064: 1052: 1048: 1042: 1039: 1028:on 2019-02-20 1027: 1023: 1019: 1013: 1010: 999: 995: 989: 986: 975: 971: 965: 962: 957: 953: 948: 943: 939: 935: 931: 927: 923: 917: 914: 903: 899: 893: 890: 885: 881: 876: 871: 867: 863: 859: 855: 851: 847: 843: 839: 835: 827: 824: 819: 815: 810: 805: 801: 797: 793: 789: 785: 781: 777: 770: 768: 764: 752: 748: 742: 740: 738: 734: 723: 719: 713: 710: 705: 701: 696: 691: 687: 683: 679: 675: 671: 667: 663: 656: 654: 650: 638: 634: 630: 624: 621: 616: 615: 607: 604: 599: 595: 590: 585: 581: 577: 573: 569: 565: 561: 557: 550: 547: 534: 528: 525: 512: 506: 503: 492: 488: 482: 479: 473: 468: 466: 461: 458: 456: 451: 448: 446: 441: 440: 439: 438: 432: 428: 424: 420: 417: 415: 410: 408: 404: 401:, 2430–2433. 400: 396: 393: 391: 386: 384: 380: 376: 372: 368: 366: 361: 359: 355: 352: 349: 345: 343: 339: 334: 331: 328: 324: 321: 318: 317: 312: 310: 307: 303: 300: 297: 296: 291: 290: 286: 281: 278: 275: 272: 269: 266: 263: 260: 257: 256: 255: 249: 247: 245: 237: 235: 233: 229: 225: 221: 217: 213: 209: 205: 201: 197: 196:John P. 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Index

University of Michigan
University of California, Berkeley
Biocatalysis
Organic chemistry
University of Michigan
Life Sciences Institute
Thesis
New Reactions and Synthetic Strategies toward Indolizidine Alkaloids and Pallavicinia Diterpenes
Doctoral advisor
Richmond Sarpong
David H. Sherman
chemist
University of Michigan
College of Literature, Science, and the Arts
Michigan Life Sciences Institute
Cheboygan
Michigan
Frankenmuth
University of Michigan
John P. Wolfe
tetrahydrofuran
Richmond Sarpong
University of California, Berkeley
University of Michigan
David Sherman's
cytochrome P450 enzymes
C-H functionalization
Life Sciences Institute
biocatalysts
American Chemical Society

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