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Andrzej Tarkowski

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217:(in this technique genetically engineered stem cells are aggregated with developing embryo. Chimaera obtained this way is phenotypically changed and passes it to the next generation). In 1966 Tarkowski developed a technique which enabled observing chromosome in oocytes, which has been widely used in early studies of embryo (Tarkowski, 1967; Cytogenetics). This publication is often cited, although has been publicised over 50 years ago. In later years professor Tarkowski with his collaborators showed for the first time in history that parthenogenetically activated mouse oocytes are able of developing until mid-gestation (Tarkowski, et al.,1970;Nature). It was a serious argument for the hypothesis of 201:
Royal Society at the University of Oxford (UK), Rockefeller University of New York (USA), University of Adelaide (Australia) and Institute of Jacques Monod CNRS and Paris University XVII (France). Tarkowski was also a member of the Polish Academy of Sciences, the Polish Academy of Arts and Sciences, the French Academy of Sciences, the American Academy of Sciences, and Academia Europaea. In 1997–2004 he was also a member of the Advisory Board of the Foundation for Polish Science.
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that a single blastomere isolated from a 2-cell stage mouse embryo is fully able to develop and the result is healthy and fertile mouse (Tarkowski, 1959, Nature). His next achievement was, reported in 1961, birth of first chimaeric mice produced experimentally by injecting blastomeres from one embryo to genetically different embryo (Tarkowski, 1961;Nature). Since then the chimaera has become a useful tool, used in producing
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In 1972 he was appointed professor. He eventually received full professorship in 1978. From 1964 until his retirement in 2003 he was the head of the Department of Embryology, and during two periods (1972–1981; 1987–2003) he was the head of the Institute of Zoology in the Faculty of Biology, University of Warsaw.
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In 1950 Tarkowski was admitted to study at the Faculty of Biology and Earth Sciences (currently the Faculty of Biology) University of Warsaw. He graduated in 1955 with M.Sc. degree. His Ph.D. was received in 1959, and in 1963 he reached a D.Sc. degree at the Faculty of Biology, University of Warsaw.
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Tarkowski contributed to international science throughout his professional life. He collaborated with many research centers around the world. He was a Fellow of the Rockefeller Foundation in the Department of Zoology, University College of North Wales (UK), and served as a visiting professor of the
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Pioneering work of Andrzej K. Tarkowski initiated in 1950s formed the basis not only for modern mammalian developmental biology and progress in animal breeding, but also in such techniques as assisted reproduction (in vitro fertilisation) or preimplantational diagnostics. In 1959 Tarkowski showed
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The achievements of Tarkowski have been honored with prestigious scientific awards such as the Albert Brachet Prize of the Royal Academy of Belgium (1980), Polish National Award (1980), the Alfred Jurzykowski Foundation Award (1984), the Embryo Transfer Pioneer Award, the International Embryo
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Professor Tarkowski was passionate about photography. His photographic exhibitions – "Botanical impressions", "Tree and Wood", "The Earth We Walk On" and "On the Border of Nature and Abstraction" – have been appreciated in many Polish cities.
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Tarkowski et al. (2005) Identical triplets and twins developed from isolated blastomeres of 8- and 16-cell mouse embryos supported with tetraploid blastomeres. Int. J. Dev. Biol. 49, 825-832.
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Tarkowski, A.K., Witkowska, A. and Opas, J. (1977) Development of cytochalasin B-induced tetraploid and diploid/tetraploid mosaic mouse embryos. J. Embryol. exp. Morph. 41, 47-64.
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Tarkowski et al. (2001) Mouse singletons and twins developed from isolated diploid blastomeres supported with tetraploid blastomeres. Int. J. Dev. Biol. 45, 591-596.
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Czolowska, R., Modlinski, J.A. and Tarkowski, A.K. (1984) Behaviour of thymocyte nuclei in non-activated and activated mouse oocytes. J. Cell Sci. 69, 19-34.
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Tarkowski, A.K. and Wroblewska, J. (1967) Development of blastomeres of mouse eggs isolated at the 4- and 8-cell stage. J. Embryol. exp. Morph., 18, 155-180.
221:. Mutually with his Ph.D. student Jacek Kubiak, Tarkowski devised a technique of blastomere electrofusion leading to the generation of tetraploid embryo. 101: 310:
Tarkowski et al. (2010) Individual blastomeres of 16- and 32- cell mouse embryos are able to develop into foetuses and mice. Dev. Biol. 348, 190-198.
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Although Professor Tarkowski retired in 2003, he still continued his researches by undertaking new experiments and inventing new techniques.
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Suwińska et al. (2005) Experimentally produced diploid-triploid mouse chimaeras develop up to adulthood. Mol. Rep. Dev. 72, 362-376.
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Tarkowski, A.K. and Rossant, J. (1976) Haploid mouse blastocysts developed from bisected zygotes. Nature 259, 663-665.
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Tarkowski, A.K., Witkowska, A., and Nowicka, J. (1970) Experimental parthenogenesis in the mouse. Nature 226, 162-165.
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Tarkowski, A.K. (1959) Experiments on the development of isolated blastomeres of mouse eggs. Nature 184, 1286-1287
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Tarkowski, A.K. (1966) An air-drying method for chromosome preparations from mouse eggs. Cytogenetics 5, 394-400.
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Kubiak and Tarkowski (1985)Electrofusion of mouse blastomeres. Exp. Cell Res. 157, 561-566.
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Tarkowski, A.K. (1961) Mouse chimaeras developed from fused eggs. Nature 190, 857-860.
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for their discoveries concerning the early development of mammalian embryos.
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Transfer Society Award (1991), and the Commander's Cross with star of the
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Foreign associates of the National Academy of Sciences
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He also received a Doctor Honoris Causa degree at the
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Tarkowski 1933–2016" 1002:/ John Frederick Grassle (2013) 433:Reproductive BioMedicine Online 1: 712:Ernest John Christopher Polge 547:Foundation for Polish Science 269:Most influential publications 248:Foundation for Polish Science 329:"The Japan Prize Foundation" 215:genetically modified animals 92:Albert Brachet Prize (1980) 543:Information about Tarkowski 168:of the twentieth century – 141:[ˈan.dʐɛjtarkɔfski] 133:Andrzej Krzysztof Tarkowski 33:Andrzej Krzysztof Tarkowski 1217: 446:10.1016/j.rbmo.2017.03.001 263:Medical University of Łódź 244:Order of Polonia Restituta 728:William Hayward Pickering 603:Ephraim Katchalski-Katzir 126: 108: 869:/ Keith J. Sainsbury / 259:Jagiellonian University 1040:Emmanuelle Charpentier 659:Frank Sherwood Rowland 170:in vitro fertilization 250:Prize (2013) and the 137:Polish pronunciation: 1145:John Michael Wallace 72:University of Warsaw 1129:/ Kazuo Hagimoto / 968:Tadamitsu Kishimoto 698:Jacques-Louis Lions 148:and a professor at 81:Mammalian embryos, 16:Polish embryologist 1107:Robert A. Weinberg 1089:Robert G. Gallager 1034:Steven D. Tanksley 1020:Theodore Friedmann 923:Victor A. McKusick 881:Masatoshi Takeichi 829:Timothy R. Parsons 825:John B. Goodenough 819:Kimishige Ishizaka 794:Jack L. Strominger 790:W. Wesley Peterson 770:Hiroyuki Yoshikawa 766:Joseph Engelberger 742:Edward F. Knipling 261:(2000) and at the 237:Honours and awards 219:genomic imprinting 1181:Polish biologists 1158: 1157: 1127:Masataka Nakazawa 1121:Christopher Field 1006:Yasuharu Suematsu 950:Shun-ichi Iwasaki 909:Peter Shaw Ashton 849:Benoit Mandelbrot 843:Andrzej Tarkowski 663:Elias James Corey 150:Warsaw University 130: 129: 122:, animal genetics 110:Scientific career 51:23 September 2016 23:Andrzej Tarkowski 1208: 996:C. Grant Willson 784:Marc Van Montagu 758:Takashi Sugimura 692:Xavier Le Pichon 637:Donald Henderson 633:Georges Vendryes 577: 570: 563: 554: 530: 529: 527: 526: 517:. Archived from 511: 505: 504: 502: 500: 490: 484: 483: 481: 479: 465: 459: 458: 448: 421: 412: 411: 409: 407: 397: 391: 386: 380: 379: 377: 375: 360: 354: 353: 346: 340: 339: 337: 335: 325: 143: 138: 54: 19: 1216: 1215: 1211: 1210: 1209: 1207: 1206: 1205: 1161: 1160: 1159: 1154: 1149:Ronald M. Evans 1135:Karl Deisseroth 1131:Gero Miesenböck 1103:Bert Vogelstein 1099:Martin A. Green 1077: 1058:Max Dale Cooper 1044:Jennifer Doudna 1016:Yutaka Takahasi 938: 885:Erkki Ruoslahti 867:Akira Fujishima 835:Tim Berners-Lee 803: 798:Don Craig Wiley 684:W. Jason Morgan 668: 627:Theodore Maiman 613:Willem J. Kolff 587: 581: 539: 534: 533: 524: 522: 513: 512: 508: 498: 496: 492: 491: 487: 477: 475: 467: 466: 462: 423: 422: 415: 405: 403: 399: 398: 394: 387: 383: 373: 371: 362: 361: 357: 348: 347: 343: 333: 331: 327: 326: 322: 317: 271: 239: 230: 210: 194: 136: 100: 95: 93: 68:Alma mater 52: 43: 37: 35: 34: 24: 17: 12: 11: 5: 1214: 1212: 1204: 1203: 1198: 1193: 1188: 1183: 1178: 1173: 1163: 1162: 1156: 1155: 1153: 1152: 1138: 1124: 1113:Katalin Karikó 1110: 1096: 1085: 1083: 1079: 1078: 1076: 1075: 1068:Yoshio Okamoto 1065: 1062:Jacques Miller 1051: 1037: 1027: 1013: 1010:C. David Allis 1003: 993: 986:Nicholas Lydon 975: 964:Dennis Ritchie 957: 954:Peter Vitousek 946: 944: 940: 939: 937: 936: 929:Dennis Meadows 926: 919:Robert E. Kahn 912: 905:Peter Grünberg 898: 888: 874: 871:John H. Lawton 860: 853:James A. Yorke 846: 832: 822: 811: 809: 805: 804: 802: 801: 787: 773: 755: 748:Charles K. Kao 745: 735: 732:Arvid Carlsson 725: 722:Kary B. Mullis 715: 705: 695: 676: 674: 670: 669: 667: 666: 656: 649:Luc Montagnier 630: 619:Henry Beachell 616: 609:David Turnbull 606: 599:John R. Pierce 595: 593: 589: 588: 582: 580: 579: 572: 565: 557: 551: 550: 538: 537:External links 535: 532: 531: 506: 485: 460: 425:Selwood, Lynne 413: 392: 381: 355: 341: 319: 318: 316: 313: 312: 311: 308: 305: 302: 299: 296: 293: 290: 287: 284: 281: 278: 275: 270: 267: 238: 235: 229: 226: 209: 206: 193: 190: 128: 127: 124: 123: 117: 113: 112: 106: 105: 90: 86: 85: 83:Mouse chimeras 79: 78:Known for 75: 74: 69: 65: 64: 61: 57: 56: 55:(aged 83) 49: 45: 44: 38: 32: 30: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 1213: 1202: 1199: 1197: 1194: 1192: 1189: 1187: 1184: 1182: 1179: 1177: 1174: 1172: 1169: 1168: 1166: 1150: 1146: 1142: 1141:Brian Hoskins 1139: 1136: 1132: 1128: 1125: 1122: 1118: 1117:Drew Weissman 1114: 1111: 1108: 1104: 1100: 1097: 1094: 1090: 1087: 1086: 1084: 1080: 1073: 1069: 1066: 1063: 1059: 1055: 1054:Akira Yoshino 1052: 1049: 1045: 1041: 1038: 1035: 1031: 1028: 1025: 1024:Alain Fischer 1021: 1017: 1014: 1011: 1007: 1004: 1001: 997: 994: 991: 990:Masato Sagawa 987: 983: 979: 976: 973: 972:Toshio Hirano 969: 965: 961: 958: 955: 951: 948: 947: 945: 941: 934: 933:David E. 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Wild 688:Dan McKenzie 653:Robert Gallo 645:Frank Fenner 623:Gurdev Khush 523:. Retrieved 519:the original 509: 497:. Retrieved 488: 476:. Retrieved 472: 463: 436: 432: 404:. Retrieved 395: 384: 372:. Retrieved 368: 358: 344: 332:. Retrieved 323: 256: 240: 231: 223: 211: 203: 199: 195: 182:Anne McLaren 146:embryologist 132: 131: 109: 53:(2016-09-23) 1176:2016 deaths 1171:1933 births 901:Albert Fert 857:Seiji Ogawa 718:Frank Press 584:Japan Prize 499:24 November 478:24 November 406:24 November 334:24 November 252:Japan Prize 186:Japan Prize 158:blastomeres 97:Japan Prize 60:Citizenship 1165:Categories 1072:Rattan Lal 1048:Adi Shamir 895:Akira Endo 815:Ian McHarg 762:Bruce Ames 641:Isao Arita 586:recipients 525:2016-09-24 439:(6): 556. 369:nature.com 315:References 120:Embryology 36:4 May 1933 915:Vint Cerf 776:Leo Esaki 752:Masao Ito 455:1472-6483 178:stem cell 254:(2002). 208:Research 184:won the 166:medicine 42:, Poland 549:webpage 174:cloning 162:biology 154:embryos 99:(2002) 1151:(2024) 1137:(2023) 1123:(2022) 1109:(2021) 1095:(2020) 1074:(2019) 1064:(2018) 1050:(2017) 1036:(2016) 1026:(2015) 1012:(2014) 992:(2012) 974:(2011) 956:(2010) 935:(2009) 925:(2008) 911:(2007) 897:(2006) 887:(2005) 873:(2004) 859:(2003) 845:(2002) 831:(2001) 821:(2000) 800:(1999) 786:(1998) 772:(1997) 754:(1996) 744:(1995) 740:Jr. / 734:(1994) 724:(1993) 714:(1992) 704:(1991) 694:(1990) 665:(1989) 655:(1988) 629:(1987) 615:(1986) 605:(1985) 453:  192:Career 116:Fields 104:(2013) 89:Awards 63:Polish 40:Warsaw 1082:2020s 943:2010s 808:2000s 673:1990s 592:1980s 374:4 May 501:2014 480:2014 451:ISSN 408:2014 376:2023 336:2014 176:and 164:and 156:and 48:Died 29:Born 441:doi 1167:: 1147:/ 1143:/ 1133:/ 1119:/ 1115:/ 1105:/ 1101:/ 1091:/ 1070:/ 1060:/ 1056:/ 1046:/ 1042:/ 1032:/ 1022:/ 1018:/ 1008:/ 998:/ 988:/ 984:/ 980:/ 970:/ 966:/ 962:/ 952:/ 931:/ 921:/ 917:/ 907:/ 903:/ 893:/ 883:/ 879:/ 865:/ 855:/ 851:/ 841:/ 837:/ 827:/ 817:/ 796:/ 792:/ 782:/ 778:/ 768:/ 764:/ 760:/ 750:/ 730:/ 720:/ 710:/ 700:/ 690:/ 686:/ 682:/ 661:/ 651:/ 647:/ 643:/ 639:/ 635:/ 625:/ 621:/ 611:/ 601:/ 545:- 471:. 449:. 437:34 435:. 431:. 416:^ 367:. 172:, 576:e 569:t 562:v 528:. 503:. 482:. 457:. 443:: 410:. 378:. 352:. 338:. 135:(

Index

Warsaw
University of Warsaw
Mouse chimeras
Japan Prize
Prize of the Foundation for Polish Science
Embryology
[ˈan.dʐɛjtarkɔfski]
embryologist
Warsaw University
embryos
blastomeres
biology
medicine
in vitro fertilization
cloning
stem cell
Anne McLaren
Japan Prize
genetically modified animals
genomic imprinting
Order of Polonia Restituta
Foundation for Polish Science
Japan Prize
Jagiellonian University
Medical University of Łódź
"The Japan Prize Foundation"
"International Embryo Technology Society (IETS)"
"Andrzej K. Tarkowski 1933–2016"
Warsaw University's Department of Biology website
"2002 (18th) JAPAN PRIZE LAUREATES"

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