247:
224:
121:
146:
5479:
498:
253:
152:
29:
1135:
protein into an outward-facing conformation, releasing HCO3- into the extracellular environment and capturing Cl- into the binding pocket. Finally, the AE2 protein returns to its inward-facing conformation and releases Cl- into the cytosol. This working cycle of the AE2 protein replaces a weak acid anion with a strong acid anion, thereby lowering the cellular pH and re-balancing pH homeostasis.
1125:
The cryo electron microscopic studies revealed that human AE2 protein forms a homodimer and stays in resting state of inward-facing conformation at physiological pH. A loop between transmembrane (TM) helices 10 and 11 extends from TM domain into its cytoplamic domain, forming a "trigger" locking the
1134:
During the process of acid secretion, the cellular pH increases, triggering the release of the "trigger" loop from the cytoplasmic domain. This allows for the re-arrangement of the TM helices, while the CTD loop is forced out, enabling HCO3- binding. Further conformational changes then turn the AE2
1552:
Huang QR, Li Q, Chen YH, Li L, Liu LL, Lei SH, et al. (June 2010). "Involvement of anion exchanger-2 in apoptosis of endothelial cells induced by high glucose through an mPTP-ROS-Caspase-3 dependent pathway".
2083:
Mobasheri A, Golding S, Pagakis SN, Corkey K, Pocock AE, Fermor B, et al. (1999). "Expression of cation exchanger NHE and anion exchanger AE isoforms in primary human bone-derived osteoblasts".
2054:
Jöns T, Drenckhahn D (March 1998). "Anion exchanger 2 (AE2) binds to erythrocyte ankyrin and is colocalized with ankyrin along the basolateral plasma membrane of human gastric parietal cells".
2227:
Medina JF, Lecanda J, Acín A, Ciesielczyk P, Prieto J (January 2000). "Tissue-specific N-terminal isoforms from overlapping alternate promoters of the human AE2 anion exchanger gene".
1906:
Havenga MJ, Bosman GJ, Appelhans H, De Grip WJ (August 1994). "Expression of the anion exchanger (AE) gene family in human brain. Identification of a new AE protein: AE0".
260:
159:
5520:
2392:
5413:
3772:
2360:
82:
2328:
Soleimani M, Greeley T, Petrovic S, Wang Z, Amlal H, Kopp P, Burnham CE (February 2001). "Pendrin: an apical Cl/OH/HCO exchanger in the kidney cortex".
761:
742:
4813:
1126:
TM helices in the resting state. In addition, the C-terminal loop (CTD loop) inserts into the anion binding pocket to further block its activities.
3678:
1725:
Gehrig H, Müller W, Appelhans H (April 1992). "Complete nucleotide sequence of band 3 related anion transport protein AE2 from human kidney".
5208:
4734:
1224:
1206:
5539:
5066:
2934:
2603:
2264:
Vince JW, Reithmeier RA (May 2000). "Identification of the carbonic anhydrase II binding site in the Cl(-)/HCO(3)(-) anion exchanger AE1".
2370:
5513:
4076:
3570:
2496:
2491:
2416:
2385:
993:
246:
1970:
Medina JF, Acín A, Prieto J (January 1997). "Molecular cloning and characterization of the human AE2 anion exchanger (SLC4A2) gene".
5462:
5363:
4530:
3492:
2790:
2704:
2461:
1000:
223:
3294:
1269:
2120:
Hyde K, Harrison D, Hollingsworth MA, Harris A (September 1999). "Chloride-bicarbonate exchangers in the human fetal pancreas".
5549:
3555:
2631:
2476:
1193:
1172:
5403:
3030:
2007:
García C, Montuenga LM, Medina JF, Prieto J (March 1998). "In situ detection of AE2 anion-exchanger mRNA in the human liver".
5544:
5506:
5383:
5378:
5349:
3890:
3454:
3256:
3251:
2378:
1189:
145:
120:
3449:
3444:
3439:
3424:
3419:
3414:
3409:
3199:
4775:
4577:
4377:
1168:
5373:
2151:"Primary structure of a sperm cell anion exchanger and its messenger ribonucleic acid expression during spermatogenesis"
62:
3365:
4345:
2186:"Localization of a gene for autosomal recessive distal renal tubular acidosis with normal hearing (rdRTA2) to 7q33-34"
259:
158:
4224:
1503:"Putative re-entrant loop 1 of AE2 transmembrane domain has a major role in acute regulation of anion exchange by pH"
1270:"Entrez Gene: SLC4A2 solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)"
3928:
4297:
2800:
2409:
1077:
1056:
252:
151:
4954:
4610:
3103:
5358:
3246:
5142:
5408:
3230:
2997:
806:
70:
5099:
3626:
2295:"Identification of the full-length AE2 (AE2a) isoform as the Golgi-associated anion exchanger in fibroblasts"
5368:
5000:
2729:
787:
1095:
1285:"AE2 Cl-/HCO3- exchanger is required for normal cAMP-stimulated anion secretion in murine proximal colon"
5344:
5180:
4866:
4051:
3976:
3370:
3241:
3236:
2810:
2412:
1756:"Associations of human erythrocyte band 4.2. Binding to ankyrin and to the cytoplasmic domain of band 3"
1144:
5441:
5436:
3403:
2805:
1674:
1404:
1345:
1242:
Tanner MJ (January 1993). "Molecular and cellular biology of the erythrocyte anion exchanger (AE1)".
134:
49:
5033:
2739:
2514:
1087:
972:
947:
943:
939:
909:
884:
880:
876:
2795:
2252:
2108:
2042:
1995:
1869:"Identification of a band-3 binding site near the N-terminus of erythrocyte membrane protein 4.2"
1663:"HCO3-/Cl- anion exchanger SLC4A2 is required for proper osteoclast differentiation and function"
1643:
1578:
1393:"HCO3-/Cl- anion exchanger SLC4A2 is required for proper osteoclast differentiation and function"
94:
1450:
Josephsen K, Praetorius J, Frische S, Gawenis LR, Kwon TH, Agre P, et al. (February 2009).
976:
951:
913:
888:
4936:
4931:
4279:
4274:
4201:
4196:
4191:
4186:
4181:
4176:
4156:
4151:
4146:
4141:
4126:
4116:
4106:
4101:
4091:
4066:
3872:
3857:
3852:
3474:
3469:
3464:
2345:
2316:
2281:
2244:
2215:
2172:
2137:
2100:
2071:
2034:
1987:
1958:
1923:
1894:
1855:
1820:
1777:
1742:
1702:
1635:
1617:
1570:
1534:
1483:
1432:
1373:
1314:
1251:
1114:
42:
5490:
5190:
5157:
5124:
5114:
5081:
5076:
5010:
4891:
4843:
4833:
4790:
4754:
4749:
4716:
4711:
4706:
4701:
4692:
4687:
4682:
4654:
4644:
4635:
4630:
4625:
4460:
4445:
4440:
4425:
4392:
4359:
4269:
4229:
3986:
3958:
3943:
3938:
3933:
3910:
3905:
3753:
3749:
3740:
3698:
3522:
3512:
3502:
3434:
3380:
3314:
3299:
3133:
3128:
3123:
2974:
2875:
2870:
2840:
2764:
2759:
2754:
2681:
2184:
Karet FE, Finberg KE, Nayir A, Bakkaloglu A, Ozen S, Hulton SA, et al. (December 1999).
5486:
5478:
5236:
3337:
3075:
3065:
3050:
3012:
3007:
2825:
2749:
2676:
2401:
2337:
2306:
2273:
2236:
2205:
2197:
2162:
2129:
2092:
2063:
2024:
2016:
1979:
1948:
1915:
1884:
1876:
1845:
1810:
1802:
1767:
1734:
1692:
1682:
1625:
1609:
1562:
1524:
1514:
1473:
1463:
1422:
1412:
1363:
1353:
1304:
1296:
497:
339:
270:
214:
169:
90:
1832:
Palumbo AP, Isobe M, Huebner K, Shane S, Rovera G, Demuth D, et al. (September 1986).
5320:
2405:
1789:
Demuth DR, Showe LC, Ballantine M, Palumbo A, Fraser PJ, Cioe L, et al. (June 1986).
314:
1332:
Medina JF, Recalde S, Prieto J, Lecanda J, Saez E, Funk CD, et al. (December 2003).
1678:
1630:
1597:
1408:
1349:
2210:
2185:
1889:
1868:
1850:
1833:
1815:
1806:
1790:
1697:
1662:
1529:
1502:
1478:
1451:
1427:
1392:
1309:
1284:
1099:
2149:
Holappa K, Mustonen M, Parvinen M, Vihko P, Rajaniemi H, Kellokumpu S (October 1999).
2067:
1791:"Cloning and structural characterization of a human non-erythroid band 3-like protein"
1772:
1755:
1368:
1333:
676:
671:
666:
661:
656:
651:
646:
641:
636:
631:
626:
610:
605:
600:
595:
590:
585:
580:
564:
559:
554:
549:
544:
539:
5533:
5336:
2364:
2341:
1919:
1738:
1647:
1598:"The structural basis of the pH-homeostasis mediated by the Cl−/HCO3− exchanger, AE2"
1452:"Targeted disruption of the Cl-/HCO3- exchanger Ae2 results in osteopetrosis in mice"
526:
2256:
2112:
2046:
1582:
332:
111:
74:
1999:
28:
98:
4959:
4415:
4011:
3212:
1229:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1211:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1074:
2311:
2294:
2167:
2150:
1667:
Proceedings of the
National Academy of Sciences of the United States of America
1613:
1456:
Proceedings of the
National Academy of Sciences of the United States of America
1397:
Proceedings of the
National Academy of Sciences of the United States of America
1338:
Proceedings of the
National Academy of Sciences of the United States of America
415:
5395:
4553:
1566:
1103:
231:
128:
78:
1834:"Chromosomal localization of a human band 3-like gene to region 7q35----7q36"
1621:
1300:
5332:
1937:"Normalization and subtraction: two approaches to facilitate gene discovery"
1687:
1468:
1417:
1358:
706:
475:
353:
298:
285:
197:
184:
86:
2349:
2320:
2285:
2248:
2240:
2219:
2176:
2141:
2133:
2104:
2096:
1983:
1706:
1639:
1574:
1538:
1519:
1487:
1436:
1377:
1318:
2075:
2038:
2020:
1991:
1962:
1927:
1898:
1859:
1824:
1781:
1746:
1255:
1040:
1035:
4926:
4921:
4916:
4848:
4465:
4206:
4171:
4166:
4161:
4136:
4131:
4121:
4111:
4096:
4086:
4081:
4071:
4061:
4056:
4046:
4036:
4031:
4026:
3867:
3862:
3847:
3842:
3837:
3832:
3827:
3822:
3592:
3459:
2786:
1070:
1024:
851:
832:
5293:
5288:
5283:
5278:
5273:
5268:
5218:
5213:
5185:
5162:
5152:
5147:
5119:
5109:
5104:
5071:
5015:
5005:
4911:
4906:
4901:
4896:
4886:
4881:
4876:
4871:
4838:
4828:
4823:
4818:
4795:
4785:
4780:
4757:
4744:
4739:
4673:
4668:
4659:
4649:
4620:
4615:
4592:
4587:
4582:
4559:
4535:
4512:
4455:
4450:
4435:
4430:
4420:
4397:
4387:
4382:
4354:
4349:
4327:
4322:
4317:
4312:
4307:
4302:
4264:
4259:
4254:
4249:
4244:
4239:
4234:
4021:
4016:
4006:
4001:
3996:
3991:
3981:
3953:
3948:
3900:
3895:
3817:
3812:
3807:
3802:
3797:
3792:
3787:
3782:
3777:
3735:
3726:
3717:
3712:
3703:
3693:
3688:
3683:
3637:
3632:
3608:
3603:
3598:
3537:
3532:
3527:
3517:
3507:
3497:
3429:
3385:
3375:
3347:
3342:
3319:
3309:
3304:
3276:
3271:
3266:
3261:
3209:
3204:
3160:
3155:
3150:
3145:
3138:
3118:
3113:
3108:
3085:
3080:
2979:
2969:
2964:
2890:
2885:
2880:
2865:
2860:
2855:
2850:
2845:
2686:
2584:
2579:
2574:
2569:
2564:
2029:
1953:
1936:
818:
773:
2277:
1880:
1596:
Zhang Q, Jian L, Yao D, Rao B, Xia Y, Hu K, et al. (2023-03-31).
5417:
4506:
4041:
3588:
3070:
3060:
3055:
3045:
3040:
3035:
3002:
2959:
2954:
2949:
2944:
2926:
2921:
2916:
2911:
2835:
2830:
2820:
2815:
2782:
2744:
2734:
2724:
2719:
2709:
2671:
2666:
2661:
2656:
2651:
2646:
2641:
2636:
2613:
2608:
2559:
2549:
2544:
2486:
2481:
2471:
2466:
1289:
American
Journal of Physiology. Gastrointestinal and Liver Physiology
1067:
1008:
728:
1283:
Gawenis LR, Bradford EM, Alper SL, Prasad V, Shull GE (April 2010).
2201:
1727:
Biochimica et
Biophysica Acta (BBA) - Gene Structure and Expression
53:, AE2, BND3L, EPB3L1, HKB3, NBND3, solute carrier family 4 member 2
3565:
3560:
2714:
2554:
2539:
2534:
2529:
2524:
2519:
1501:
Stewart AK, Kurschat CE, Vaughan-Jones RD, Alper SL (March 2009).
1086:
have been used to explore the function of AE2. AE2 contributes to
691:
687:
5048:
5043:
5038:
2939:
1083:
1063:
66:
5318:
5257:
4982:
4814:
System A & N, sodium-coupled neutral amino-acid transporter
4488:
3660:
3181:
2443:
2428:
2374:
2293:
Holappa K, Suokas M, Soininen P, Kellokumpu S (February 2001).
506:
1334:"Anion exchanger 2 is essential for spermiogenesis in mice"
1107:
2462:
high affinity glutamate and neutral amino-acid transporter
2908:
cationic amino-acid transporter/glycoprotein-associated
322:
5494:
2933:
glycoprotein-associated/light or catalytic subunits of
1113:
AE3 has been suggested as a target for prevention of
487:
5067:
Na-independent, system-L like amino-acid transporter
5394:
5331:
5229:
5201:
5173:
5135:
5092:
5059:
5026:
4993:
4947:
4859:
4806:
4768:
4727:
4603:
4570:
4546:
4523:
4499:
4408:
4370:
4338:
4290:
4217:
3969:
3921:
3883:
3765:
3671:
3619:
3581:
3548:
3485:
3396:
3358:
3330:
3287:
3223:
3192:
3096:
3023:
2990:
2901:
2775:
2697:
2624:
2595:
2507:
2454:
2229:
2122:
965:
932:
902:
869:
1935:Bonaldo MF, Lennon G, Soares MB (September 1996).
1661:Wu J, Glimcher LH, Aliprantis AO (November 2008).
1391:Wu J, Glimcher LH, Aliprantis AO (November 2008).
1185:
1183:
1181:
1164:
1162:
1160:
269:
168:
2330:American Journal of Physiology. Renal Physiology
2299:The Journal of Histochemistry and Cytochemistry
1867:Rybicki AC, Musto S, Schwartz RS (July 1995).
1190:GRCm38: Ensembl release 89: ENSMUSG00000028962
1106:function. The activity of AE2 is sensitive to
5514:
2386:
8:
3773:organic cation/anion/zwitterion transporter
1169:GRCh38: Ensembl release 89: ENSG00000164889
5521:
5507:
5328:
5315:
5254:
4990:
4979:
4496:
4485:
3668:
3657:
3295:human Na-sulfate/carboxylate cotransporter
3189:
3178:
2451:
2440:
2436:
2425:
2393:
2379:
2371:
2361:United States National Library of Medicine
702:
522:
310:
209:
106:
2310:
2209:
2166:
2028:
1952:
1888:
1849:
1814:
1771:
1696:
1686:
1629:
1528:
1518:
1477:
1467:
1426:
1416:
1367:
1357:
1308:
2359:This article incorporates text from the
1908:Brain Research. Molecular Brain Research
545:anion transmembrane transporter activity
3891:Na+-dependent ascorbic acid transporter
1156:
3679:Organic anion-transporting polypeptide
18:
4735:proton-coupled amino-acid transporter
2935:heterodimeric amino-acid transporters
2604:heterodimeric amino-acid transporters
1066:. AE2 is functionally similar to the
611:integral component of plasma membrane
565:sodium:bicarbonate symporter activity
274:
235:
230:
173:
132:
127:
7:
5475:
5473:
3200:proton coupled metal ion transporter
1875:. 309. 309 ( Pt 2) (Pt 2): 677–681.
1102:in mice. AE2 is required for normal
438:vestibular membrane of cochlear duct
4776:sugar-phosphate/phosphate exchanger
4378:facilitative nucleoside transporter
1760:The Journal of Biological Chemistry
1507:The Journal of Biological Chemistry
5493:. You can help Knowledge (XXG) by
4578:type II Na-phosphate cotransporter
2791:sodium:neurotransmitter symporters
2190:American Journal of Human Genetics
1838:American Journal of Human Genetics
1807:10.1002/j.1460-2075.1986.tb04348.x
1754:Korsgren C, Cohen CM (July 1988).
962:
929:
899:
866:
842:
823:
797:
778:
752:
733:
672:sodium ion transmembrane transport
560:inorganic anion exchanger activity
492:
426:choroid plexus of fourth ventricle
410:
348:
327:
14:
4531:Vesicular glutamate transporter 1
3493:Vesicular glutamate transporter 1
3366:proton oligopeptide cotransporter
1059:that in humans is encoded by the
5477:
2342:10.1152/ajprenal.2001.280.2.f356
2056:European Journal of Cell Biology
496:
258:
251:
245:
222:
157:
150:
144:
119:
27:
4346:Na-coupled nucleoside transport
4225:multifunctional anion exchanger
3556:vesicular monoamine transporter
647:regulation of intracellular pH
581:integral component of membrane
507:More reference expression data
476:More reference expression data
1:
5209:multidrug and toxin extrusion
4298:fatty acid transport proteins
2515:facilitative GLUT transporter
2068:10.1016/s0171-9335(98)80117-9
1773:10.1016/S0021-9258(19)81500-4
662:anion transmembrane transport
368:muscle layer of sigmoid colon
243:
142:
4955:basolateral iron transporter
4611:nucleoside-sugar transporter
3104:sodium bile salt cotransport
2705:sodium glucose cotransporter
1920:10.1016/0169-328X(94)90283-6
1739:10.1016/0167-4781(92)90446-7
434:Epithelium of choroid plexus
5540:Genes on human chromosome 7
2410:membrane transport proteins
627:digestive tract development
591:basolateral plasma membrane
392:stromal cell of endometrium
5566:
5472:
5143:Putative sugar transporter
2312:10.1177/002215540104900213
2168:10.1095/biolreprod61.4.981
2085:Cell Biology International
1614:10.1038/s41467-023-37557-y
1057:membrane transport protein
450:retinal pigment epithelium
380:mucosa of transverse colon
5458:
5327:
5314:
5264:
5253:
4989:
4978:
4495:
4484:
3667:
3656:
3188:
3177:
2450:
2439:
2435:
2424:
1567:10.1007/s10495-010-0477-9
1225:"Mouse PubMed Reference:"
1207:"Human PubMed Reference:"
1130:Mechanism of ion exchange
1039:
1034:
1030:
1023:
1007:
994:Chr 7: 151.06 – 151.08 Mb
988:
969:
936:
925:
906:
873:
862:
849:
845:
830:
826:
817:
804:
800:
785:
781:
772:
759:
755:
740:
736:
727:
712:
705:
701:
685:
652:inorganic anion transport
525:
521:
504:
495:
486:
473:
422:
413:
360:
351:
321:
313:
309:
292:
279:
242:
221:
212:
208:
191:
178:
141:
118:
109:
105:
60:
57:
47:
40:
35:
26:
21:
5463:solute carrier disorders
5100:Choline-like transporter
3231:electroneutral cation-Cl
2009:Cell and Tissue Research
1301:10.1152/ajpgi.00178.2009
1053:Anion exchange protein 2
5001:Magnesium transporter E
2632:bicarbonate transporter
2155:Biology of Reproduction
1873:The Biochemical Journal
1688:10.1073/pnas.0808763105
1469:10.1073/pnas.0811682106
1418:10.1073/pnas.0808763105
1359:10.1073/pnas.2536127100
1001:Chr 5: 24.63 – 24.65 Mb
657:transmembrane transport
16:Protein found in humans
5550:Membrane protein stubs
5489:–related article is a
5396:Antiporter (exchanger)
2241:10.1006/bbrc.1999.1951
2134:10.1006/bbrc.1999.1367
2097:10.1006/cbir.1998.0299
1984:10.1006/geno.1996.4467
1520:10.1074/jbc.M802051200
1244:Seminars in Hematology
1098:. AE2 is required for
1096:gastrointestinal tract
596:apical plasma membrane
446:mucous cell of stomach
5545:Solute carrier family
4867:metal ion transporter
3977:mitochondrial carrier
3627:type III Na-phosphate
2021:10.1007/s004410051017
1602:Nature Communications
1145:Solute carrier family
1115:diabetic vasculopathy
667:bicarbonate transport
430:epithelium of stomach
1088:basolateral membrane
555:transporter activity
276:5 A3|5 11.74 cM
237:Chromosome 5 (mouse)
135:Chromosome 7 (human)
5034:Ammonia transporter
3929:Na/(Ca-K) exchanger
1766:(21): 10212–10218.
1679:2008PNAS..10516934W
1673:(44): 16934–16939.
1409:2008PNAS..10516934W
1403:(44): 16934–16939.
1350:2003PNAS..10015847M
1344:(26): 15847–15852.
550:antiporter activity
376:right lobe of liver
372:canal of the cervix
5181:Folate transporter
2602:heavy subunits of
2363:, which is in the
1954:10.1101/gr.6.9.791
807:ENSMUSG00000028962
620:Biological process
574:Cellular component
533:Molecular function
99:SLC4A2 - orthologs
5502:
5501:
5470:
5469:
5454:
5453:
5450:
5449:
5310:
5309:
5306:
5305:
5302:
5301:
5249:
5248:
5245:
5244:
4974:
4973:
4970:
4969:
4480:
4479:
4476:
4475:
3652:
3651:
3648:
3647:
3173:
3172:
3169:
3168:
2402:Membrane proteins
2278:10.1021/bi992564p
2272:(18): 5527–5533.
1881:10.1042/bj3090677
1513:(10): 6126–6139.
1094:transport in the
1050:
1049:
1046:
1045:
1019:
1018:
984:
983:
959:
958:
921:
920:
896:
895:
858:
857:
839:
838:
813:
812:
794:
793:
768:
767:
749:
748:
697:
696:
517:
516:
513:
512:
482:
481:
469:
468:
407:
406:
396:left uterine tube
305:
304:
204:
203:
5557:
5523:
5516:
5509:
5487:membrane protein
5481:
5474:
5429:
5428:
5427:
5329:
5316:
5255:
5237:Heme transporter
4991:
4980:
4497:
4486:
3669:
3658:
3338:urea transporter
3190:
3179:
2452:
2441:
2437:
2426:
2406:carrier proteins
2395:
2388:
2381:
2372:
2353:
2336:(2): F356–F364.
2324:
2314:
2289:
2260:
2223:
2213:
2196:(6): 1656–1665.
2180:
2170:
2145:
2116:
2091:(7–8): 551–562.
2079:
2050:
2032:
2003:
1966:
1956:
1931:
1902:
1892:
1863:
1853:
1828:
1818:
1801:(6): 1205–1214.
1795:The EMBO Journal
1785:
1775:
1750:
1711:
1710:
1700:
1690:
1658:
1652:
1651:
1633:
1593:
1587:
1586:
1549:
1543:
1542:
1532:
1522:
1498:
1492:
1491:
1481:
1471:
1462:(5): 1638–1641.
1447:
1441:
1440:
1430:
1420:
1388:
1382:
1381:
1371:
1361:
1329:
1323:
1322:
1312:
1295:(4): G493–G503.
1280:
1274:
1273:
1266:
1260:
1259:
1239:
1233:
1232:
1221:
1215:
1214:
1203:
1197:
1187:
1176:
1166:
1032:
1031:
1003:
996:
979:
963:
954:
930:
926:RefSeq (protein)
916:
900:
891:
867:
843:
824:
798:
779:
753:
734:
703:
523:
509:
500:
493:
478:
418:
416:Top expressed in
411:
388:body of pancreas
356:
354:Top expressed in
349:
328:
311:
301:
288:
277:
262:
255:
249:
238:
226:
210:
200:
187:
176:
161:
154:
148:
137:
123:
107:
101:
52:
45:
31:
19:
5565:
5564:
5560:
5559:
5558:
5556:
5555:
5554:
5530:
5529:
5528:
5527:
5471:
5466:
5446:
5426:
5423:
5422:
5421:
5419:
5390:
5353:
5323:
5298:
5260:
5241:
5225:
5197:
5169:
5131:
5088:
5055:
5022:
4985:
4966:
4943:
4855:
4802:
4764:
4723:
4599:
4566:
4542:
4519:
4491:
4472:
4404:
4366:
4334:
4286:
4213:
3965:
3917:
3879:
3761:
3663:
3644:
3615:
3577:
3544:
3481:
3404:monocarboxylate
3392:
3354:
3326:
3283:
3219:
3184:
3165:
3092:
3019:
2998:Na/Ca exchanger
2986:
2897:
2771:
2693:
2620:
2591:
2503:
2446:
2431:
2420:
2399:
2356:
2327:
2292:
2263:
2226:
2183:
2148:
2119:
2082:
2053:
2006:
1969:
1941:Genome Research
1934:
1914:(1–2): 97–104.
1905:
1866:
1831:
1788:
1753:
1724:
1720:
1718:Further reading
1715:
1714:
1660:
1659:
1655:
1595:
1594:
1590:
1551:
1550:
1546:
1500:
1499:
1495:
1449:
1448:
1444:
1390:
1389:
1385:
1331:
1330:
1326:
1282:
1281:
1277:
1268:
1267:
1263:
1241:
1240:
1236:
1223:
1222:
1218:
1205:
1204:
1200:
1188:
1179:
1167:
1158:
1153:
1141:
1132:
1123:
1093:
1041:View/Edit Mouse
1036:View/Edit Human
999:
992:
989:Location (UCSC)
975:
971:
950:
946:
942:
938:
912:
908:
887:
883:
879:
875:
788:ENSG00000164889
681:
637:spermatogenesis
632:anion transport
615:
586:plasma membrane
569:
505:
474:
465:
460:
456:
452:
448:
444:
440:
436:
432:
428:
414:
403:
398:
394:
390:
386:
382:
378:
374:
370:
366:
364:body of stomach
352:
296:
283:
275:
265:
264:
263:
256:
236:
213:Gene location (
195:
182:
174:
164:
163:
162:
155:
133:
110:Gene location (
61:
48:
41:
17:
12:
11:
5:
5563:
5561:
5553:
5552:
5547:
5542:
5532:
5531:
5526:
5525:
5518:
5511:
5503:
5500:
5499:
5482:
5468:
5467:
5459:
5456:
5455:
5452:
5451:
5448:
5447:
5445:
5444:
5439:
5434:
5433:
5432:
5424:
5406:
5400:
5398:
5392:
5391:
5389:
5388:
5387:
5386:
5381:
5371:
5366:
5361:
5356:
5351:
5347:
5341:
5339:
5325:
5324:
5319:
5312:
5311:
5308:
5307:
5304:
5303:
5300:
5299:
5297:
5296:
5291:
5286:
5281:
5276:
5271:
5265:
5262:
5261:
5258:
5251:
5250:
5247:
5246:
5243:
5242:
5240:
5239:
5233:
5231:
5227:
5226:
5224:
5223:
5222:
5221:
5216:
5205:
5203:
5199:
5198:
5196:
5195:
5194:
5193:
5188:
5177:
5175:
5171:
5170:
5168:
5167:
5166:
5165:
5160:
5155:
5150:
5139:
5137:
5133:
5132:
5130:
5129:
5128:
5127:
5122:
5117:
5112:
5107:
5096:
5094:
5090:
5089:
5087:
5086:
5085:
5084:
5079:
5074:
5063:
5061:
5057:
5056:
5054:
5053:
5052:
5051:
5046:
5041:
5030:
5028:
5024:
5023:
5021:
5020:
5019:
5018:
5013:
5008:
4997:
4995:
4987:
4986:
4983:
4976:
4975:
4972:
4971:
4968:
4967:
4965:
4964:
4963:
4962:
4951:
4949:
4945:
4944:
4942:
4941:
4940:
4939:
4934:
4929:
4924:
4919:
4914:
4909:
4904:
4899:
4894:
4889:
4884:
4879:
4874:
4863:
4861:
4857:
4856:
4854:
4853:
4852:
4851:
4846:
4841:
4836:
4831:
4826:
4821:
4810:
4808:
4804:
4803:
4801:
4800:
4799:
4798:
4793:
4788:
4783:
4772:
4770:
4766:
4765:
4763:
4762:
4761:
4760:
4752:
4747:
4742:
4731:
4729:
4725:
4724:
4722:
4721:
4720:
4719:
4714:
4709:
4704:
4697:
4696:
4695:
4690:
4685:
4678:
4677:
4676:
4671:
4664:
4663:
4662:
4657:
4652:
4647:
4640:
4639:
4638:
4633:
4628:
4623:
4618:
4607:
4605:
4601:
4600:
4598:
4597:
4596:
4595:
4590:
4585:
4574:
4572:
4568:
4567:
4565:
4564:
4563:
4562:
4550:
4548:
4544:
4543:
4541:
4540:
4539:
4538:
4527:
4525:
4521:
4520:
4518:
4517:
4516:
4515:
4503:
4501:
4493:
4492:
4489:
4482:
4481:
4478:
4477:
4474:
4473:
4471:
4470:
4469:
4468:
4463:
4458:
4453:
4448:
4443:
4438:
4433:
4428:
4423:
4412:
4410:
4406:
4405:
4403:
4402:
4401:
4400:
4395:
4390:
4385:
4374:
4372:
4368:
4367:
4365:
4364:
4363:
4362:
4357:
4342:
4340:
4336:
4335:
4333:
4332:
4331:
4330:
4325:
4320:
4315:
4310:
4305:
4294:
4292:
4288:
4287:
4285:
4284:
4283:
4282:
4277:
4272:
4267:
4262:
4257:
4252:
4247:
4242:
4237:
4232:
4221:
4219:
4215:
4214:
4212:
4211:
4210:
4209:
4204:
4199:
4194:
4189:
4184:
4179:
4174:
4169:
4164:
4159:
4154:
4149:
4144:
4139:
4134:
4129:
4124:
4119:
4114:
4109:
4104:
4099:
4094:
4089:
4084:
4079:
4074:
4069:
4064:
4059:
4054:
4049:
4044:
4039:
4034:
4029:
4024:
4019:
4014:
4009:
4004:
3999:
3994:
3989:
3984:
3973:
3971:
3967:
3966:
3964:
3963:
3962:
3961:
3956:
3951:
3946:
3941:
3936:
3925:
3923:
3919:
3918:
3916:
3915:
3914:
3913:
3908:
3903:
3898:
3887:
3885:
3881:
3880:
3878:
3877:
3876:
3875:
3870:
3865:
3860:
3855:
3850:
3845:
3840:
3835:
3830:
3825:
3820:
3815:
3810:
3805:
3800:
3795:
3790:
3785:
3780:
3769:
3767:
3763:
3762:
3760:
3759:
3758:
3757:
3745:
3744:
3743:
3738:
3731:
3730:
3729:
3722:
3721:
3720:
3715:
3708:
3707:
3706:
3701:
3696:
3691:
3686:
3675:
3673:
3665:
3664:
3661:
3654:
3653:
3650:
3649:
3646:
3645:
3643:
3642:
3641:
3640:
3635:
3629:cotransporter
3623:
3621:
3617:
3616:
3614:
3613:
3612:
3611:
3606:
3601:
3585:
3583:
3579:
3578:
3576:
3575:
3574:
3573:
3568:
3563:
3552:
3550:
3546:
3545:
3543:
3542:
3541:
3540:
3535:
3530:
3525:
3520:
3515:
3510:
3505:
3500:
3489:
3487:
3483:
3482:
3480:
3479:
3478:
3477:
3472:
3467:
3462:
3457:
3452:
3447:
3442:
3437:
3432:
3427:
3422:
3417:
3412:
3400:
3398:
3394:
3393:
3391:
3390:
3389:
3388:
3383:
3378:
3373:
3362:
3360:
3356:
3355:
3353:
3352:
3351:
3350:
3345:
3334:
3332:
3328:
3327:
3325:
3324:
3323:
3322:
3317:
3312:
3307:
3302:
3291:
3289:
3285:
3284:
3282:
3281:
3280:
3279:
3274:
3269:
3264:
3259:
3254:
3249:
3244:
3239:
3233:cotransporter
3227:
3225:
3221:
3220:
3218:
3217:
3216:
3215:
3207:
3196:
3194:
3186:
3185:
3182:
3175:
3174:
3171:
3170:
3167:
3166:
3164:
3163:
3158:
3153:
3148:
3143:
3142:
3141:
3136:
3131:
3126:
3121:
3116:
3111:
3100:
3098:
3094:
3093:
3091:
3090:
3089:
3088:
3083:
3078:
3073:
3068:
3063:
3058:
3053:
3048:
3043:
3038:
3031:Na/H exchanger
3027:
3025:
3021:
3020:
3018:
3017:
3016:
3015:
3010:
3005:
2994:
2992:
2988:
2987:
2985:
2984:
2983:
2982:
2977:
2972:
2967:
2962:
2957:
2952:
2947:
2942:
2931:
2930:
2929:
2924:
2919:
2914:
2905:
2903:
2899:
2898:
2896:
2895:
2894:
2893:
2888:
2883:
2878:
2873:
2868:
2863:
2858:
2853:
2848:
2843:
2838:
2833:
2828:
2823:
2818:
2813:
2808:
2803:
2798:
2779:
2777:
2773:
2772:
2770:
2769:
2768:
2767:
2762:
2757:
2752:
2747:
2742:
2737:
2732:
2727:
2722:
2717:
2712:
2701:
2699:
2695:
2694:
2692:
2691:
2690:
2689:
2684:
2679:
2674:
2669:
2664:
2659:
2654:
2649:
2644:
2639:
2628:
2626:
2622:
2621:
2619:
2618:
2617:
2616:
2611:
2599:
2597:
2593:
2592:
2590:
2589:
2588:
2587:
2582:
2577:
2572:
2567:
2562:
2557:
2552:
2547:
2542:
2537:
2532:
2527:
2522:
2511:
2509:
2505:
2504:
2502:
2501:
2500:
2499:
2494:
2489:
2484:
2479:
2474:
2469:
2458:
2456:
2448:
2447:
2444:
2433:
2432:
2429:
2422:
2421:
2413:solute carrier
2400:
2398:
2397:
2390:
2383:
2375:
2355:
2354:
2325:
2305:(2): 259–269.
2290:
2261:
2235:(1): 228–235.
2224:
2202:10.1086/302679
2181:
2161:(4): 981–986.
2146:
2128:(2): 315–321.
2117:
2080:
2062:(3): 232–236.
2051:
2015:(3): 481–488.
2004:
1967:
1947:(9): 791–806.
1932:
1903:
1864:
1844:(3): 307–316.
1829:
1786:
1751:
1733:(3): 326–328.
1721:
1719:
1716:
1713:
1712:
1653:
1588:
1561:(6): 693–704.
1544:
1493:
1442:
1383:
1324:
1275:
1261:
1234:
1216:
1198:
1177:
1155:
1154:
1152:
1149:
1148:
1147:
1140:
1137:
1131:
1128:
1122:
1119:
1100:spermiogenesis
1091:
1048:
1047:
1044:
1043:
1038:
1028:
1027:
1021:
1020:
1017:
1016:
1014:
1012:
1005:
1004:
997:
990:
986:
985:
982:
981:
967:
966:
960:
957:
956:
934:
933:
927:
923:
922:
919:
918:
904:
903:
897:
894:
893:
871:
870:
864:
860:
859:
856:
855:
847:
846:
840:
837:
836:
828:
827:
821:
815:
814:
811:
810:
802:
801:
795:
792:
791:
783:
782:
776:
770:
769:
766:
765:
757:
756:
750:
747:
746:
738:
737:
731:
725:
724:
719:
714:
710:
709:
699:
698:
695:
694:
683:
682:
680:
679:
674:
669:
664:
659:
654:
649:
644:
639:
634:
629:
623:
621:
617:
616:
614:
613:
608:
606:focal adhesion
603:
598:
593:
588:
583:
577:
575:
571:
570:
568:
567:
562:
557:
552:
547:
542:
540:enzyme binding
536:
534:
530:
529:
519:
518:
515:
514:
511:
510:
502:
501:
490:
484:
483:
480:
479:
471:
470:
467:
466:
464:
463:
459:
455:
454:pyloric antrum
451:
447:
443:
439:
435:
431:
427:
423:
420:
419:
408:
405:
404:
402:
401:
397:
393:
389:
385:
384:body of uterus
381:
377:
373:
369:
365:
361:
358:
357:
345:
344:
336:
325:
319:
318:
315:RNA expression
307:
306:
303:
302:
294:
290:
289:
281:
278:
273:
267:
266:
257:
250:
244:
240:
239:
234:
228:
227:
219:
218:
206:
205:
202:
201:
193:
189:
188:
180:
177:
172:
166:
165:
156:
149:
143:
139:
138:
131:
125:
124:
116:
115:
103:
102:
59:
55:
54:
46:
38:
37:
33:
32:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
5562:
5551:
5548:
5546:
5543:
5541:
5538:
5537:
5535:
5524:
5519:
5517:
5512:
5510:
5505:
5504:
5498:
5496:
5492:
5488:
5483:
5480:
5476:
5465:
5464:
5457:
5443:
5440:
5438:
5435:
5431:
5415:
5412:
5411:
5410:
5407:
5405:
5402:
5401:
5399:
5397:
5393:
5385:
5382:
5380:
5377:
5376:
5375:
5372:
5370:
5367:
5365:
5362:
5360:
5357:
5355:
5348:
5346:
5343:
5342:
5340:
5338:
5337:Cotransporter
5334:
5330:
5326:
5322:
5317:
5313:
5295:
5292:
5290:
5287:
5285:
5282:
5280:
5277:
5275:
5272:
5270:
5267:
5266:
5263:
5256:
5252:
5238:
5235:
5234:
5232:
5228:
5220:
5217:
5215:
5212:
5211:
5210:
5207:
5206:
5204:
5200:
5192:
5189:
5187:
5184:
5183:
5182:
5179:
5178:
5176:
5172:
5164:
5161:
5159:
5156:
5154:
5151:
5149:
5146:
5145:
5144:
5141:
5140:
5138:
5134:
5126:
5123:
5121:
5118:
5116:
5113:
5111:
5108:
5106:
5103:
5102:
5101:
5098:
5097:
5095:
5091:
5083:
5080:
5078:
5075:
5073:
5070:
5069:
5068:
5065:
5064:
5062:
5058:
5050:
5047:
5045:
5042:
5040:
5037:
5036:
5035:
5032:
5031:
5029:
5025:
5017:
5014:
5012:
5009:
5007:
5004:
5003:
5002:
4999:
4998:
4996:
4992:
4988:
4981:
4977:
4961:
4958:
4957:
4956:
4953:
4952:
4950:
4946:
4938:
4935:
4933:
4930:
4928:
4925:
4923:
4920:
4918:
4915:
4913:
4910:
4908:
4905:
4903:
4900:
4898:
4895:
4893:
4890:
4888:
4885:
4883:
4880:
4878:
4875:
4873:
4870:
4869:
4868:
4865:
4864:
4862:
4858:
4850:
4847:
4845:
4842:
4840:
4837:
4835:
4832:
4830:
4827:
4825:
4822:
4820:
4817:
4816:
4815:
4812:
4811:
4809:
4805:
4797:
4794:
4792:
4789:
4787:
4784:
4782:
4779:
4778:
4777:
4774:
4773:
4771:
4767:
4759:
4756:
4753:
4751:
4748:
4746:
4743:
4741:
4738:
4737:
4736:
4733:
4732:
4730:
4726:
4718:
4715:
4713:
4710:
4708:
4705:
4703:
4700:
4699:
4698:
4694:
4691:
4689:
4686:
4684:
4681:
4680:
4679:
4675:
4672:
4670:
4667:
4666:
4665:
4661:
4658:
4656:
4653:
4651:
4648:
4646:
4643:
4642:
4641:
4637:
4634:
4632:
4629:
4627:
4624:
4622:
4619:
4617:
4614:
4613:
4612:
4609:
4608:
4606:
4602:
4594:
4591:
4589:
4586:
4584:
4581:
4580:
4579:
4576:
4575:
4573:
4569:
4561:
4558:
4557:
4555:
4552:
4551:
4549:
4545:
4537:
4534:
4533:
4532:
4529:
4528:
4526:
4522:
4514:
4511:
4510:
4508:
4505:
4504:
4502:
4498:
4494:
4487:
4483:
4467:
4464:
4462:
4459:
4457:
4454:
4452:
4449:
4447:
4444:
4442:
4439:
4437:
4434:
4432:
4429:
4427:
4424:
4422:
4419:
4418:
4417:
4414:
4413:
4411:
4407:
4399:
4396:
4394:
4391:
4389:
4386:
4384:
4381:
4380:
4379:
4376:
4375:
4373:
4369:
4361:
4358:
4356:
4353:
4352:
4351:
4347:
4344:
4343:
4341:
4337:
4329:
4326:
4324:
4321:
4319:
4316:
4314:
4311:
4309:
4306:
4304:
4301:
4300:
4299:
4296:
4295:
4293:
4289:
4281:
4278:
4276:
4273:
4271:
4268:
4266:
4263:
4261:
4258:
4256:
4253:
4251:
4248:
4246:
4243:
4241:
4238:
4236:
4233:
4231:
4228:
4227:
4226:
4223:
4222:
4220:
4216:
4208:
4205:
4203:
4200:
4198:
4195:
4193:
4190:
4188:
4185:
4183:
4180:
4178:
4175:
4173:
4170:
4168:
4165:
4163:
4160:
4158:
4155:
4153:
4150:
4148:
4145:
4143:
4140:
4138:
4135:
4133:
4130:
4128:
4125:
4123:
4120:
4118:
4115:
4113:
4110:
4108:
4105:
4103:
4100:
4098:
4095:
4093:
4090:
4088:
4085:
4083:
4080:
4078:
4075:
4073:
4070:
4068:
4065:
4063:
4060:
4058:
4055:
4053:
4050:
4048:
4045:
4043:
4040:
4038:
4035:
4033:
4030:
4028:
4025:
4023:
4020:
4018:
4015:
4013:
4010:
4008:
4005:
4003:
4000:
3998:
3995:
3993:
3990:
3988:
3985:
3983:
3980:
3979:
3978:
3975:
3974:
3972:
3968:
3960:
3957:
3955:
3952:
3950:
3947:
3945:
3942:
3940:
3937:
3935:
3932:
3931:
3930:
3927:
3926:
3924:
3920:
3912:
3909:
3907:
3904:
3902:
3899:
3897:
3894:
3893:
3892:
3889:
3888:
3886:
3882:
3874:
3871:
3869:
3866:
3864:
3861:
3859:
3856:
3854:
3851:
3849:
3846:
3844:
3841:
3839:
3836:
3834:
3831:
3829:
3826:
3824:
3821:
3819:
3816:
3814:
3811:
3809:
3806:
3804:
3801:
3799:
3796:
3794:
3791:
3789:
3786:
3784:
3781:
3779:
3776:
3775:
3774:
3771:
3770:
3768:
3764:
3755:
3751:
3748:
3747:
3746:
3742:
3739:
3737:
3734:
3733:
3732:
3728:
3725:
3724:
3723:
3719:
3716:
3714:
3711:
3710:
3709:
3705:
3702:
3700:
3697:
3695:
3692:
3690:
3687:
3685:
3682:
3681:
3680:
3677:
3676:
3674:
3670:
3666:
3659:
3655:
3639:
3636:
3634:
3631:
3630:
3628:
3625:
3624:
3622:
3618:
3610:
3607:
3605:
3602:
3600:
3597:
3596:
3594:
3590:
3587:
3586:
3584:
3580:
3572:
3569:
3567:
3564:
3562:
3559:
3558:
3557:
3554:
3553:
3551:
3547:
3539:
3536:
3534:
3531:
3529:
3526:
3524:
3521:
3519:
3516:
3514:
3511:
3509:
3506:
3504:
3501:
3499:
3496:
3495:
3494:
3491:
3490:
3488:
3484:
3476:
3473:
3471:
3468:
3466:
3463:
3461:
3458:
3456:
3453:
3451:
3448:
3446:
3443:
3441:
3438:
3436:
3433:
3431:
3428:
3426:
3423:
3421:
3418:
3416:
3413:
3411:
3408:
3407:
3405:
3402:
3401:
3399:
3395:
3387:
3384:
3382:
3379:
3377:
3374:
3372:
3369:
3368:
3367:
3364:
3363:
3361:
3357:
3349:
3346:
3344:
3341:
3340:
3339:
3336:
3335:
3333:
3329:
3321:
3318:
3316:
3313:
3311:
3308:
3306:
3303:
3301:
3298:
3297:
3296:
3293:
3292:
3290:
3286:
3278:
3275:
3273:
3270:
3268:
3265:
3263:
3260:
3258:
3255:
3253:
3250:
3248:
3245:
3243:
3240:
3238:
3235:
3234:
3232:
3229:
3228:
3226:
3222:
3214:
3211:
3208:
3206:
3203:
3202:
3201:
3198:
3197:
3195:
3191:
3187:
3180:
3176:
3162:
3159:
3157:
3154:
3152:
3149:
3147:
3144:
3140:
3137:
3135:
3132:
3130:
3127:
3125:
3122:
3120:
3117:
3115:
3112:
3110:
3107:
3106:
3105:
3102:
3101:
3099:
3095:
3087:
3084:
3082:
3079:
3077:
3074:
3072:
3069:
3067:
3064:
3062:
3059:
3057:
3054:
3052:
3049:
3047:
3044:
3042:
3039:
3037:
3034:
3033:
3032:
3029:
3028:
3026:
3022:
3014:
3011:
3009:
3006:
3004:
3001:
3000:
2999:
2996:
2995:
2993:
2989:
2981:
2978:
2976:
2973:
2971:
2968:
2966:
2963:
2961:
2958:
2956:
2953:
2951:
2948:
2946:
2943:
2941:
2938:
2937:
2936:
2932:
2928:
2925:
2923:
2920:
2918:
2915:
2913:
2910:
2909:
2907:
2906:
2904:
2900:
2892:
2889:
2887:
2884:
2882:
2879:
2877:
2874:
2872:
2869:
2867:
2864:
2862:
2859:
2857:
2854:
2852:
2849:
2847:
2844:
2842:
2839:
2837:
2834:
2832:
2829:
2827:
2824:
2822:
2819:
2817:
2814:
2812:
2809:
2807:
2804:
2802:
2799:
2797:
2794:
2793:
2792:
2788:
2784:
2781:
2780:
2778:
2774:
2766:
2763:
2761:
2758:
2756:
2753:
2751:
2748:
2746:
2743:
2741:
2738:
2736:
2733:
2731:
2728:
2726:
2723:
2721:
2718:
2716:
2713:
2711:
2708:
2707:
2706:
2703:
2702:
2700:
2696:
2688:
2685:
2683:
2680:
2678:
2675:
2673:
2670:
2668:
2665:
2663:
2660:
2658:
2655:
2653:
2650:
2648:
2645:
2643:
2640:
2638:
2635:
2634:
2633:
2630:
2629:
2627:
2623:
2615:
2612:
2610:
2607:
2606:
2605:
2601:
2600:
2598:
2594:
2586:
2583:
2581:
2578:
2576:
2573:
2571:
2568:
2566:
2563:
2561:
2558:
2556:
2553:
2551:
2548:
2546:
2543:
2541:
2538:
2536:
2533:
2531:
2528:
2526:
2523:
2521:
2518:
2517:
2516:
2513:
2512:
2510:
2506:
2498:
2495:
2493:
2490:
2488:
2485:
2483:
2480:
2478:
2475:
2473:
2470:
2468:
2465:
2464:
2463:
2460:
2459:
2457:
2453:
2449:
2442:
2438:
2434:
2427:
2423:
2418:
2414:
2411:
2407:
2403:
2396:
2391:
2389:
2384:
2382:
2377:
2376:
2373:
2369:
2368:
2366:
2365:public domain
2362:
2351:
2347:
2343:
2339:
2335:
2331:
2326:
2322:
2318:
2313:
2308:
2304:
2300:
2296:
2291:
2287:
2283:
2279:
2275:
2271:
2267:
2262:
2258:
2254:
2250:
2246:
2242:
2238:
2234:
2230:
2225:
2221:
2217:
2212:
2207:
2203:
2199:
2195:
2191:
2187:
2182:
2178:
2174:
2169:
2164:
2160:
2156:
2152:
2147:
2143:
2139:
2135:
2131:
2127:
2123:
2118:
2114:
2110:
2106:
2102:
2098:
2094:
2090:
2086:
2081:
2077:
2073:
2069:
2065:
2061:
2057:
2052:
2048:
2044:
2040:
2036:
2031:
2026:
2022:
2018:
2014:
2010:
2005:
2001:
1997:
1993:
1989:
1985:
1981:
1977:
1973:
1968:
1964:
1960:
1955:
1950:
1946:
1942:
1938:
1933:
1929:
1925:
1921:
1917:
1913:
1909:
1904:
1900:
1896:
1891:
1886:
1882:
1878:
1874:
1870:
1865:
1861:
1857:
1852:
1847:
1843:
1839:
1835:
1830:
1826:
1822:
1817:
1812:
1808:
1804:
1800:
1796:
1792:
1787:
1783:
1779:
1774:
1769:
1765:
1761:
1757:
1752:
1748:
1744:
1740:
1736:
1732:
1728:
1723:
1722:
1717:
1708:
1704:
1699:
1694:
1689:
1684:
1680:
1676:
1672:
1668:
1664:
1657:
1654:
1649:
1645:
1641:
1637:
1632:
1627:
1623:
1619:
1615:
1611:
1607:
1603:
1599:
1592:
1589:
1584:
1580:
1576:
1572:
1568:
1564:
1560:
1556:
1548:
1545:
1540:
1536:
1531:
1526:
1521:
1516:
1512:
1508:
1504:
1497:
1494:
1489:
1485:
1480:
1475:
1470:
1465:
1461:
1457:
1453:
1446:
1443:
1438:
1434:
1429:
1424:
1419:
1414:
1410:
1406:
1402:
1398:
1394:
1387:
1384:
1379:
1375:
1370:
1365:
1360:
1355:
1351:
1347:
1343:
1339:
1335:
1328:
1325:
1320:
1316:
1311:
1306:
1302:
1298:
1294:
1290:
1286:
1279:
1276:
1271:
1265:
1262:
1257:
1253:
1249:
1245:
1238:
1235:
1230:
1226:
1220:
1217:
1212:
1208:
1202:
1199:
1195:
1191:
1186:
1184:
1182:
1178:
1174:
1170:
1165:
1163:
1161:
1157:
1150:
1146:
1143:
1142:
1138:
1136:
1129:
1127:
1120:
1118:
1116:
1111:
1109:
1105:
1101:
1097:
1089:
1085:
1081:
1079:
1076:
1072:
1069:
1065:
1062:
1058:
1054:
1042:
1037:
1033:
1029:
1026:
1022:
1015:
1013:
1010:
1006:
1002:
998:
995:
991:
987:
980:
978:
974:
968:
964:
961:
955:
953:
949:
945:
941:
935:
931:
928:
924:
917:
915:
911:
905:
901:
898:
892:
890:
886:
882:
878:
872:
868:
865:
863:RefSeq (mRNA)
861:
854:
853:
848:
844:
841:
835:
834:
829:
825:
822:
820:
816:
809:
808:
803:
799:
796:
790:
789:
784:
780:
777:
775:
771:
764:
763:
758:
754:
751:
745:
744:
739:
735:
732:
730:
726:
723:
720:
718:
715:
711:
708:
704:
700:
693:
689:
684:
678:
675:
673:
670:
668:
665:
663:
660:
658:
655:
653:
650:
648:
645:
643:
642:ion transport
640:
638:
635:
633:
630:
628:
625:
624:
622:
619:
618:
612:
609:
607:
604:
602:
599:
597:
594:
592:
589:
587:
584:
582:
579:
578:
576:
573:
572:
566:
563:
561:
558:
556:
553:
551:
548:
546:
543:
541:
538:
537:
535:
532:
531:
528:
527:Gene ontology
524:
520:
508:
503:
499:
494:
491:
489:
485:
477:
472:
461:
457:
453:
449:
445:
441:
437:
433:
429:
425:
424:
421:
417:
412:
409:
399:
395:
391:
387:
383:
379:
375:
371:
367:
363:
362:
359:
355:
350:
347:
346:
343:
341:
337:
335:
334:
330:
329:
326:
324:
320:
316:
312:
308:
300:
295:
291:
287:
282:
272:
268:
261:
254:
248:
241:
233:
229:
225:
220:
216:
211:
207:
199:
194:
190:
186:
181:
171:
167:
160:
153:
147:
140:
136:
130:
126:
122:
117:
113:
108:
104:
100:
96:
92:
88:
84:
80:
76:
72:
68:
64:
56:
51:
44:
39:
34:
30:
25:
20:
5495:expanding it
5484:
5460:
4556:transporter
4509:transporter
3595:transporter
3406:transporter
2789:- dependent
2358:
2357:
2333:
2329:
2302:
2298:
2269:
2266:Biochemistry
2265:
2232:
2228:
2193:
2189:
2158:
2154:
2125:
2121:
2088:
2084:
2059:
2055:
2012:
2008:
1978:(1): 74–85.
1975:
1971:
1944:
1940:
1911:
1907:
1872:
1841:
1837:
1798:
1794:
1763:
1759:
1730:
1726:
1670:
1666:
1656:
1605:
1601:
1591:
1558:
1554:
1547:
1510:
1506:
1496:
1459:
1455:
1445:
1400:
1396:
1386:
1341:
1337:
1327:
1292:
1288:
1278:
1264:
1250:(1): 34–57.
1247:
1243:
1237:
1228:
1219:
1210:
1201:
1133:
1124:
1112:
1082:
1060:
1052:
1051:
973:NP_001240821
970:
948:NP_001186623
944:NP_001186622
940:NP_001186621
937:
910:NM_001253892
907:
885:NM_001199694
881:NM_001199693
877:NM_001199692
874:
850:
831:
805:
786:
760:
741:
721:
716:
338:
331:
196:151,076,526
183:151,057,210
58:External IDs
4416:zinc efflux
2030:10171/20151
1608:(1): 1812.
1055:(AE2) is a
462:granulocyte
400:right ovary
297:24,645,948
284:24,628,835
36:Identifiers
5534:Categories
5442:Cl-oxalate
5437:Cl-formate
5364:Na/glucose
4554:Acetyl-CoA
1196:, May 2017
1175:, May 2017
1151:References
1104:osteoclast
342:(ortholog)
79:HomoloGene
5461:see also
5333:Symporter
5321:Ion pumps
1648:257858182
1622:2041-1723
1555:Apoptosis
1121:Structure
1080:protein.
977:NP_033233
952:NP_003031
914:NM_009207
889:NM_003040
707:Orthologs
677:transport
87:GeneCards
5430:(Band 3)
5414:Na/(Ca-K
4984:SLC41–48
4937:SLC39A14
4932:SLC39A13
4927:SLC39A12
4922:SLC39A11
4917:SLC39A10
4849:SLC38A10
4490:SLC31–40
4466:SLC30A10
4280:SLC26A11
4275:SLC26A10
4207:SLC25A46
4202:SLC25A45
4197:SLC25A44
4192:SLC25A43
4187:SLC25A42
4182:SLC25A41
4177:SLC25A40
4172:SLC25A39
4167:SLC25A38
4162:SLC25A37
4157:SLC25A36
4152:SLC25A35
4147:SLC25A34
4142:SLC25A33
4137:SLC25A32
4132:SLC25A31
4127:SLC25A30
4122:SLC25A29
4117:SLC25A28
4112:SLC25A27
4107:SLC25A26
4102:SLC25A25
4097:SLC25A24
4092:SLC25A23
4087:SLC25A22
4082:SLC25A21
4077:SLC25A20
4072:SLC25A19
4067:SLC25A18
4062:SLC25A17
4057:SLC25A16
4052:SLC25A15
4047:SLC25A14
4042:SLC25A13
4037:SLC25A12
4032:SLC25A11
4027:SLC25A10
3873:SLC22A20
3868:SLC22A19
3863:SLC22A18
3858:SLC22A17
3853:SLC22A16
3848:SLC22A15
3843:SLC22A14
3838:SLC22A13
3833:SLC22A12
3828:SLC22A11
3823:SLC22A10
3662:SLC21–30
3593:thiamine
3475:SLC16A14
3470:SLC16A13
3465:SLC16A12
3460:SLC16A11
3455:SLC16A10
3183:SLC11–20
2787:chloride
2430:By group
2350:11208611
2321:11156694
2286:10820026
2257:26957969
2249:10623603
2220:10577919
2177:10491633
2142:10491290
2113:12201584
2105:10452823
2047:22738717
1972:Genomics
1707:18971331
1640:37002221
1631:10066210
1583:25917589
1575:20180022
1539:19103596
1488:19164575
1437:18971331
1378:14673081
1319:20110461
1192:–
1171:–
1139:See also
1078:exchange
1025:Wikidata
686:Sources:
601:membrane
442:yolk sac
5345:Na/K,Cl
5259:SLCO1–4
5219:SLC47A2
5214:SLC47A1
5191:SLC46A2
5186:SLC46A1
5163:SLC45A4
5158:SLC54A3
5153:SLC45A2
5148:SLC45A1
5125:SLC44A5
5120:SLC44A4
5115:SLC44A3
5110:SLC44A2
5105:SLC44A1
5082:SLC43A3
5077:SLC43A2
5072:SLC43A1
5016:SLC41A3
5011:SLC41A2
5006:SLC41A1
4960:SLC40A1
4912:SLC39A9
4907:SLC39A8
4902:SLC39A7
4897:SLC39A6
4892:SLC39A5
4887:SLC39A4
4882:SLC39A3
4877:SLC39A2
4872:SLC39A1
4844:SLC38A6
4839:SLC38A5
4834:SLC38A4
4829:SLC38A3
4824:SLC38A2
4819:SLC38A1
4796:SLC37A4
4791:SLC37A3
4786:SLC37A2
4781:SLC37A1
4755:SLC36A4
4750:SLC36A3
4745:SLC36A2
4740:SLC36A1
4717:SLC35E4
4712:SLC35E3
4707:SLC35E2
4702:SLC35E1
4693:SLC35D3
4688:SLC35D2
4683:SLC35D1
4674:SLC35C2
4669:SLC35C1
4660:SLC35B4
4655:SLC35B3
4650:SLC35B2
4645:SLC35B1
4636:SLC35A5
4631:SLC35A4
4626:SLC35A3
4621:SLC35A2
4616:SLC35A1
4593:SLC34A3
4588:SLC34A2
4583:SLC34A1
4560:SLC33A1
4536:SLC32A1
4513:SLC31A1
4461:SLC30A9
4456:SLC30A8
4451:SLC30A7
4446:SLC30A6
4441:SLC30A5
4436:SLC30A4
4431:SLC30A3
4426:SLC30A2
4421:SLC30A1
4398:SLC29A4
4393:SLC29A3
4388:SLC29A2
4383:SLC29A1
4360:SLC28A3
4355:SLC28A2
4350:SLC28A1
4328:SLC27A6
4323:SLC27A5
4318:SLC27A4
4313:SLC27A3
4308:SLC27A2
4303:SLC27A1
4270:SLC26A9
4265:SLC26A8
4260:SLC26A7
4255:SLC26A6
4250:SLC26A5
4245:SLC26A4
4240:SLC26A3
4235:SLC26A2
4230:SLC26A1
4022:SLC25A9
4017:SLC25A8
4012:SLC25A7
4007:SLC25A6
4002:SLC25A5
3997:SLC25A4
3992:SLC25A3
3987:SLC25A2
3982:SLC25A1
3959:SLC24A6
3954:SLC24A5
3949:SLC24A4
3944:SLC24A3
3939:SLC24A2
3934:SLC24A1
3911:SLC23A4
3906:SLC23A3
3901:SLC23A2
3896:SLC23A1
3818:SLC22A9
3813:SLC22A8
3808:SLC22A7
3803:SLC22A6
3798:SLC22A5
3793:SLC22A4
3788:SLC22A3
3783:SLC22A2
3778:SLC22A1
3754:SLCO6A1
3750:SLCO5A1
3741:SLCO4C1
3736:SLCO4A1
3727:SLCO3A1
3718:SLCO2B1
3713:SLCO2A1
3704:SLCO1C1
3699:SLCO1B4
3694:SLCO1B3
3689:SLCO1B1
3684:SLCO1A2
3638:SLC20A2
3633:SLC20A1
3609:SLC19A3
3604:SLC19A2
3599:SLC19A1
3571:SLC18A3
3566:SLC18A2
3561:SLC18A1
3538:SLC17A9
3533:SLC17A8
3528:SLC17A7
3523:SLC17A6
3518:SLC17A5
3513:SLC17A4
3508:SLC17A3
3503:SLC17A2
3498:SLC17A1
3450:SLC16A9
3445:SLC16A8
3440:SLC16A7
3435:SLC16A6
3430:SLC16A5
3425:SLC16A4
3420:SLC16A3
3415:SLC16A2
3410:SLC16A1
3386:SLC15A4
3381:SLC15A3
3376:SLC15A2
3371:SLC15A1
3348:SLC14A2
3343:SLC14A1
3320:SLC13A5
3315:SLC13A4
3310:SLC13A3
3305:SLC13A2
3300:SLC13A1
3277:SLC12A9
3272:SLC12A8
3267:SLC12A7
3262:SLC12A6
3257:SLC12A5
3252:SLC12A4
3247:SLC12A3
3242:SLC12A2
3237:SLC12A1
3210:SLC11A2
3205:SLC11A1
3139:SLC10A7
3134:SLC10A6
3129:SLC10A5
3124:SLC10A4
3119:SLC10A3
3114:SLC10A2
3109:SLC10A1
3086:SLC9A11
3081:SLC9A10
2980:SLC7A14
2975:SLC7A13
2970:SLC7A11
2965:SLC7A10
2891:SLC6A20
2886:SLC6A19
2881:SLC6A18
2876:SLC6A17
2871:SLC6A16
2866:SLC6A15
2861:SLC6A14
2856:SLC6A13
2851:SLC6A12
2846:SLC6A11
2841:SLC6A10
2445:SLC1–10
2211:1288376
2076:9587054
2039:9477304
1992:9027488
1963:8889548
1928:7984058
1899:7626035
1890:1135783
1860:3020980
1851:1683956
1825:3015590
1816:1166929
1782:2968981
1747:1562608
1698:2579356
1675:Bibcode
1530:2649077
1479:2635809
1428:2579356
1405:Bibcode
1346:Bibcode
1310:2853300
1256:8434259
1194:Ensembl
1173:Ensembl
819:UniProt
774:Ensembl
713:Species
692:QuickGO
317:pattern
43:Aliases
4507:copper
3589:folate
3076:SLC9A9
3071:SLC9A8
3066:SLC9A7
3061:SLC9A6
3056:SLC9A5
3051:SLC9A4
3046:SLC9A3
3041:SLC9A2
3036:SLC9A1
3013:SLC8A3
3008:SLC8A2
3003:SLC8A1
2960:SLC7A9
2955:SLC7A8
2950:SLC7A7
2945:SLC7A6
2940:SLC7A5
2927:SLC7A4
2922:SLC7A3
2917:SLC7A2
2912:SLC7A1
2836:SLC6A9
2831:SLC6A8
2826:SLC6A7
2821:SLC6A6
2816:SLC6A5
2811:SLC6A4
2806:SLC6A3
2801:SLC6A2
2796:SLC6A1
2785:- and
2783:sodium
2710:SLC5A1
2637:SLC4A1
2609:SLC3A1
2520:SLC2A1
2467:SLC1A1
2348:
2319:
2284:
2255:
2247:
2218:
2208:
2175:
2140:
2111:
2103:
2074:
2045:
2037:
2000:223493
1998:
1990:
1961:
1926:
1897:
1887:
1858:
1848:
1823:
1813:
1780:
1745:
1705:
1695:
1646:
1638:
1628:
1620:
1581:
1573:
1537:
1527:
1486:
1476:
1435:
1425:
1376:
1369:307656
1366:
1317:
1307:
1254:
1068:Band 3
1061:SLC4A2
1011:search
1009:PubMed
852:P13808
833:P04920
729:Entrez
488:BioGPS
175:7q36.1
91:SLC4A2
83:128699
75:109351
67:109280
50:SLC4A2
22:SLC4A2
5485:This
5409:Na/Ca
5359:Na/Cl
5230:(48):
5202:(47):
5174:(46):
5136:(45):
5093:(44):
5060:(43):
5027:(42):
4994:(41):
4948:(40):
4860:(39):
4807:(38):
4769:(37):
4728:(36):
4604:(35):
4571:(34):
4547:(33):
4524:(32):
4500:(31):
4409:(30):
4371:(29):
4339:(28):
4291:(27):
4218:(26):
3970:(25):
3922:(24):
3884:(23):
3766:(22):
3672:(21):
3620:(20):
3582:(19):
3549:(18):
3486:(17):
3397:(16):
3359:(15):
3331:(14):
3288:(13):
3224:(12):
3193:(11):
3097:(10):
2417:TC 2A
2253:S2CID
2109:S2CID
2043:S2CID
1996:S2CID
1644:S2CID
1579:S2CID
762:20535
722:Mouse
717:Human
688:Amigo
458:molar
340:Mouse
333:Human
280:Start
215:Mouse
179:Start
112:Human
5491:stub
5416:) -
5404:Na/H
5374:Cl/K
5369:Na/I
5350:Na/P
5294:O4A1
5289:O431
5284:O2B1
5279:O1B3
5274:O1B1
5269:O1A2
5049:RhCG
5044:RhBG
5039:RhAG
4758:36A2
3213:11A3
3161:10A7
3156:10A3
3151:10A2
3146:10A1
3024:(9):
2991:(8):
2902:(7):
2776:(6):
2698:(5):
2625:(4):
2596:(3):
2508:(2):
2455:(1):
2346:PMID
2317:PMID
2282:PMID
2245:PMID
2216:PMID
2173:PMID
2138:PMID
2101:PMID
2072:PMID
2035:PMID
1988:PMID
1959:PMID
1924:PMID
1895:PMID
1856:PMID
1821:PMID
1778:PMID
1743:PMID
1731:1130
1703:PMID
1636:PMID
1618:ISSN
1571:PMID
1535:PMID
1484:PMID
1433:PMID
1374:PMID
1315:PMID
1252:PMID
1084:Mice
1075:HCO3
1064:gene
743:6522
323:Bgee
271:Band
232:Chr.
170:Band
129:Chr.
63:OMIM
5420:HCO
5418:Cl/
2338:doi
2334:280
2307:doi
2274:doi
2237:doi
2233:267
2206:PMC
2198:doi
2163:doi
2130:doi
2126:263
2093:doi
2064:doi
2025:hdl
2017:doi
2013:291
1980:doi
1949:doi
1916:doi
1885:PMC
1877:doi
1846:PMC
1811:PMC
1803:doi
1768:doi
1764:263
1735:doi
1693:PMC
1683:doi
1671:105
1626:PMC
1610:doi
1563:doi
1525:PMC
1515:doi
1511:284
1474:PMC
1464:doi
1460:106
1423:PMC
1413:doi
1401:105
1364:PMC
1354:doi
1342:100
1305:PMC
1297:doi
1293:298
1090:HCO
293:End
192:End
95:OMA
71:MGI
5536::
5335:,
2765:12
2760:11
2755:10
2687:11
2682:10
2585:14
2580:13
2575:12
2570:11
2565:10
2408::
2404:,
2344:.
2332:.
2315:.
2303:49
2301:.
2297:.
2280:.
2270:39
2268:.
2251:.
2243:.
2231:.
2214:.
2204:.
2194:65
2192:.
2188:.
2171:.
2159:61
2157:.
2153:.
2136:.
2124:.
2107:.
2099:.
2089:22
2087:.
2070:.
2060:75
2058:.
2041:.
2033:.
2023:.
2011:.
1994:.
1986:.
1976:39
1974:.
1957:.
1943:.
1939:.
1922:.
1912:25
1910:.
1893:.
1883:.
1871:.
1854:.
1842:39
1840:.
1836:.
1819:.
1809:.
1797:.
1793:.
1776:.
1762:.
1758:.
1741:.
1729:.
1701:.
1691:.
1681:.
1669:.
1665:.
1642:.
1634:.
1624:.
1616:.
1606:14
1604:.
1600:.
1577:.
1569:.
1559:15
1557:.
1533:.
1523:.
1509:.
1505:.
1482:.
1472:.
1458:.
1454:.
1431:.
1421:.
1411:.
1399:.
1395:.
1372:.
1362:.
1352:.
1340:.
1336:.
1313:.
1303:.
1291:.
1287:.
1248:30
1246:.
1227:.
1209:.
1180:^
1159:^
1117:.
1110:.
1108:pH
1071:Cl
690:/
299:bp
286:bp
198:bp
185:bp
93:;
89::
85:;
81::
77:;
73::
69:;
65::
5522:e
5515:t
5508:v
5497:.
5425:3
5384:5
5379:4
5354:3
5352:i
4348:(
3756:)
3752:(
3591:/
2750:9
2745:8
2740:7
2735:6
2730:5
2725:4
2720:3
2715:2
2677:9
2672:8
2667:7
2662:6
2657:5
2652:4
2647:3
2642:2
2614:2
2560:9
2555:8
2550:7
2545:6
2540:5
2535:4
2530:3
2525:2
2497:7
2492:6
2487:5
2482:4
2477:3
2472:2
2419:)
2415:(
2394:e
2387:t
2380:v
2367:.
2352:.
2340::
2323:.
2309::
2288:.
2276::
2259:.
2239::
2222:.
2200::
2179:.
2165::
2144:.
2132::
2115:.
2095::
2078:.
2066::
2049:.
2027::
2019::
2002:.
1982::
1965:.
1951::
1945:6
1930:.
1918::
1901:.
1879::
1862:.
1827:.
1805::
1799:5
1784:.
1770::
1749:.
1737::
1709:.
1685::
1677::
1650:.
1612::
1585:.
1565::
1541:.
1517::
1490:.
1466::
1439:.
1415::
1407::
1380:.
1356::
1348::
1321:.
1299::
1272:.
1258:.
1231:.
1213:.
1092:3
1073:/
217:)
114:)
97::
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