59:
182:(CHSS) established a North American Registry in order to study a large multi-institutional cohort of patients with AAOCA. This initiative is intended to generate new knowledge concerning the natural history of AAOCA, to describe the outcomes of surgical intervention versus observation in children and young adults with AAOCA, and to generate evidence to support risk stratification among patients with AAOCA and eventually suggest evidence-based guidelines for management.
128:
75:) is a rare congenital heart defect in which a coronary artery inappropriately arises from the aorta, usually from the incorrect sinus of Valsalva. This anomalous coronary artery often takes an interarterial (between the aorta and pulmonary artery), intraconal (within the myocardium), or intramural course (within the aortic wall), and is associated with an increased risk of
31:
114:
is estimated at 0.1% to 0.3% of the general population. Neither the true risk of sudden death nor the best way to treat these patients is known with certainty. Because of the risk of sudden death, doctors face the pressure to "do something" but in the absence of long-term follow-up data, the risks
162:
Surgical intervention is indicated for coronary artery abnormalities in symptomatic patients with AAOCA (particularly with origin of the LCA from the right sinus), such as those with serious ventricular tachyarrhythmias or documented myocardial ischemia. There are no controlled studies which have
166:
The indications for intervention in asymptomatic patients with AAOCA with an intramural course are debated, especially with AAOCA RCA from the left sinus of
Valsalva. Generally refer asymptomatic patients with left coronary artery arising from the right coronary sinus for surgical repair.
360:
345:
232:
Anomalous origin of the right coronary artery originating from the pulmonary trunk (ARCAPA) is a rare but potentially fatal anomaly. The goal of surgical therapy is establishment of a physiologic bi-coronary circulation.
224:. Hospitals from across North America continue to join the study group and enroll patients. Over 140 patients with AAOCA have been enrolled by June 2011, making it the largest cohort ever assembled of this anomaly.
250:
Brothers JA, Gaynor JW, Jacobs JP, Caldarone C, Jegatheeswaran A, Jacobs ML (2010). "The registry of anomalous aortic origin of the coronary artery of the
Congenital Heart Surgeons' Society".
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185:
Patients who are diagnosed with AAOCA at or before age 30 years are eligible for this study. They should have otherwise normal heart or only minor defects such as
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102:
Children and young adults with these defects can die suddenly, especially during or just after exercise. In fact, AAOCA is the second leading cause of
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Asymptomatic patients with the right coronary artery arising from the left sinus are managed on a case-by-case basis.
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Patients who have other major heart problems that require operations are currently not included in this
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The
Registry has been enrolling new patients from participating institutions that are member of the
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563:
469:
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295:"Anomalous origin of right coronary artery from pulmonary artery with aneurysmal coronary arteries"
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Anomalous origin of the right coronary artery from the left coronary sinus on
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30:
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in children and adolescents in the United States behind hypertrophic
212:. Any other problems with coronary arteries are also not included.
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evaluated the outcome of intervention in asymptomatic individuals.
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and benefits of different management options are unconfirmed.
39:
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arises from the wrong location on the main blood vessel, the
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with an inter-arterial, potentially dangerous course.
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24:
Anomalous Aortic Origin of a
Coronary Artery (AAOCA)
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554:
531:
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293:Gallo M, Rizzati F, Padalino M, Stellin G (2016).
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806:Anomalous aortic origin of a coronary artery
69:Anomalous aortic origin of a coronary artery
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57:
29:
20:
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7:
541:Sinus venosus atrial septal defect
499:Transposition of the great vessels
222:Congenital Heart Surgeons' Society
180:Congenital Heart Surgeons' Society
14:
126:
91:in the heart that occurs when a
837:Epidemiological study projects
574:Atrioventricular septal defect
1:
516:Persistent truncus arteriosus
487:Double outlet right ventricle
479:Aortopulmonary septal defect
312:10.1016/j.crvasa.2015.07.004
858:
556:Ventricular septal defect
264:10.1017/S1047951110001095
191:Ventricular septal defect
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28:
832:Congenital heart defects
462:Congenital heart defects
195:Patent ductus arteriosus
801:Coronary artery anomaly
624:Valvular heart disease
603:Cyanotic heart disease
546:Lutembacher's syndrome
135:This section is empty.
811:Ventricular inversion
523:Aortopulmonary window
492:Taussig–Bing syndrome
610:Eisenmenger syndrome
533:Atrial septal defect
187:Atrial septal defect
104:sudden cardiac death
87:The AAOCA is a rare
564:Tetralogy of Fallot
470:Heart septal defect
402:External resources
203:pulmonary stenosis
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818:
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681:Ebstein's anomaly
618:
617:
428:
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258:(Suppl 3): 50–8.
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18:Medical condition
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796:Brugada syndrome
791:Crisscross heart
661:tricuspid valves
639:pulmonary valves
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305:(5): e515–e517.
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137:You can help by
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53:Medical genetics
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786:Cor triatriatum
752:Underdeveloped
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332:Classification
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216:Current status
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842:Rare diseases
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731:regurgitation
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721:mitral valves
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709:insufficiency
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699:aortic valves
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582:Ostium primum
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146:February 2018
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776:Dextrocardia
591:Consequences
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210:Cohort study
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139:adding to it
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89:birth defect
86:
77:sudden death
72:
68:
67:
15:
769:Uhl anomaly
299:Cor et Vasa
197:, bicuspid
826:Categories
781:Levocardia
387:DiseasesDB
237:References
112:prevalence
411:eMedicine
158:Treatment
119:Diagnosis
48:Specialty
726:stenosis
714:bicuspid
704:stenosis
676:stenosis
644:stenosis
419:ped/2506
280:23699270
272:21087560
174:Research
666:atresia
654:absence
416:med/445
381:D003330
201:, mild
504:dextro
370:746.85
278:
270:
228:ARCAPA
110:. The
55:
759:right
746:Other
632:Right
392:34206
355:Q24.5
276:S2CID
205:etc.
97:aorta
83:Cause
73:AAOCA
764:left
692:Left
509:levo
376:MeSH
365:9-CM
268:PMID
361:ICD
346:ICD
307:doi
260:doi
141:.
40:MRI
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