3329:
50:
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Amir; Bossone, Eduardo; Citro, Rodolfo; Ueyama, Takashi; Corrado, Domenico; Kurisu, Satoshi; Ruschitzka, Frank; Winchester, David; Lyon, Alexander R; Omerovic, Elmir; Bax, Jeroen J; Meimoun, Patrick; Tarantini, Giuseppe; Rihal, Charanjit; Y.-Hassan, Shams; Migliore, Federico; Horowitz, John D; Shimokawa, Hiroaki; LĂŒscher, Thomas Felix; Templin, Christian (7 June 2018).
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sufficiently different from any normal sensation that they indicate a panic disorder. Other symptoms on the list can occur in people who may or may not have panic disorder. Panic disorder does not require four or more symptoms to all be present at the same time. Causeless panic and racing heartbeat are sufficient to indicate a panic attack.
1370:
has been free of symptoms for at least six months. It is usually safest to withdraw from these drugs gradually while undergoing therapy. While drug treatment seems promising for children and adolescents, they are at an increased risk of suicide while taking these medications and their well-being should be monitored closely.
275:, confusion, or a feeling of impending doom or of losing control. Typically, symptoms reach a peak within ten minutes of onset, and last for roughly 30 minutes, but the duration can vary from seconds to hours. Although they can be extremely frightening and distressing, panic attacks themselves are not physically dangerous.
1329:
There was a meta-analysis of the comorbidity of panic disorders and agoraphobia. It used exposure therapy to treat patients over a period. Hundreds of patients were used in these studies and they all met the DSM-IV criteria for both of these disorders. A result was that thirty-two percent of patients
1369:
While the use of drugs in treating panic attacks can be very successful, it is generally recommended that people also be in some form of therapy, such as cognitive-behavioral therapy. Drug treatments are usually used throughout the duration of panic attack symptoms and discontinued after the patient
1293:
are the best treatment for panic disorder. Medication might also be appropriate in some cases." The first part of therapy is largely informational; many people are greatly helped by simply understanding exactly what panic disorder is and how many others experience it. Many people with panic disorder
858:
Many physical symptoms of anxiety, such as rapid heart rate and hand tremors, are regulated by norepinephrine. Drugs that counteract norepinephrine's effect may be effective in reducing the physical symptoms of a panic attack. Nevertheless, some drugs that increase 'background' norepinephrine levels
1298:
helps people to replace those thoughts with more realistic, positive ways of viewing the attacks. Avoidant behavior is one of the key aspects that prevent people with frequent panic attacks from functioning healthily. Exposure therapy, which includes repeated and prolonged confrontation with feared
1250:
recommends breathing exercises for those with anxiety. One such breathing exercise is a 5-2-5 count. Using the stomach (or diaphragm)âand not the chestâinhale (feel the stomach come out, as opposed to the chest expanding) for 5 seconds. As the maximal point at inhalation is reached, hold the breath
611:
Panic attacks may also occur due to short-term stressors. Significant personal loss, including an emotional attachment to a romantic partner, life transitions, and significant life changes may all trigger a panic attack to occur. A person with an anxious temperament, excessive need for reassurance,
2519:
Zvolensky, Michael J.; Gonzalez, Adam; Bonn-Miller, Marcel O.; Bernstein, Amit; Goodwin, Renee D. (February 2008). "Negative reinforcement/negative affect reduction cigarette smoking outcome expectancies: Incremental validity for anxiety focused on bodily sensations and panic attack symptoms among
1777:
Ghadri, Jelena-Rima; Wittstein, Ilan Shor; Prasad, Abhiram; Sharkey, Scott; Dote, Keigo; Akashi, Yoshihiro John; Cammann, Victoria Lucia; Crea, Filippo; Galiuto, Leonarda; Desmet, Walter; Yoshida, Tetsuro; Manfredini, Roberto; Eitel, Ingo; Kosuge, Masami; Nef, Holger M; Deshmukh, Abhishek; Lerman,
862:
Because glutamate is the primary excitatory neurotransmitter involved in the central nervous system (CNS), it can be found in almost every neural pathway in the body. Glutamate is likely involved in conditioning, which is the process by which certain fears are formed, and extinction, which is the
1365:
SSRIs carry a relatively low risk since they are not associated with much tolerance or dependence, and are difficult to overdose with. TCAs are similar to SSRIs in their many advantages but come with more common side effects such as weight gain and cognitive disturbances. They are also easier to
1258:
Although breathing into a paper bag was a common recommendation for short-term treatment of symptoms of an acute panic attack, it has been criticized as inferior to measured breathing, potentially worsening the panic attack and possibly reducing needed blood oxygen. While the paper bag technique
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that primarily consists of the fear of experiencing a difficult or embarrassing situation from which the affected cannot escape. Panic attacks are commonly linked to agoraphobia. People with severe agoraphobia may become confined to their homes, experiencing difficulty traveling from this "safe
1401:
or early adulthood. Children and older people are less commonly affected. A meta-analysis was conducted on data collected about twin studies and family studies on the link between genes and panic disorder. The researchers also examined the possibility of a link to phobias, obsessive-compulsive
282:
terminology for describing different types of panic attacks (i.e., situationally bound/cued, situationally predisposed, and unexpected/uncued) is generally simplified into two types: unexpected and expected panic attacks. Panic attacks function as a marker and prognostic factor for severity of
1227:
Muscle relaxation techniques are useful to some individuals. These can be learned using recordings, videos, or books. While muscle relaxation has proved to be less effective than cognitive-behavioral therapies in controlled trials, many people still find at least temporary relief from muscle
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People who have been diagnosed with panic disorder have approximately double the risk of coronary heart disease. Certain stress responses to depression also have been shown to increase the risk and those diagnosed with both depression and panic disorder are nearly three times more at risk.
556:
There are long-term, biological, environmental, and social causes of panic attacks. In 1993, Fava et al. proposed a staging method of understanding the origins of disorders. The first stage in developing a disorder involves predisposing factors, such as genetics, personality, and a lack of
1388:
It is not unusual to experience only one or two symptoms at a time, such as vibrations in their legs, shortness of breath, or an intense wave of heat traveling up their bodies, which is not similar to hot flashes due to estrogen shortage. Some symptoms, such as vibrations in the legs, are
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for. Panic attacks may also become situationally-bound when certain situations are associated with panic due to previously experiencing an attack in that particular situation. People may also have a cognitive or behavioral predisposition to having panic attacks in certain situations.
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Leicht, Gregor; Mulert, Christoph; Eser, Daniela; SĂ€mann, Philipp G.; Ertl, Matthias; Laenger, Anna; Karch, Susanne; Pogarell, Oliver; Meindl, Thomas; Czisch, Michael; Rupprecht, Rainer (2013). "Benzodiazepines
Counteract Rostral Anterior Cingulate Cortex Activation Induced by
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and antidepressants. Benzodiazepines are being prescribed less often because of their potential side effects, such as dependence, fatigue, slurred speech, and memory loss. Antidepressant treatments for panic attacks include selective serotonin reuptake inhibitors
3551:
Soares-Filho, Gastao L. F.; Arias-Carrion, Oscar; Santulli, Gaetano; Silva, Adriana C.; Machado, Sergio; Nardi, Alexandre M. Valenca and
Antonio E.; Nardi, AE (31 July 2014). "Chest Pain, Panic Disorder and Coronary Artery Disease: A Systematic Review".
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to accumulate their data. The results concluded that the aforementioned disorders have a genetic component and are inherited or passed down through genes. For the non-phobias, the likelihood of inheriting is 30â40%, and for the phobias, it was 50â60%.
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The symptoms of a panic attack may cause the person to feel that their body is failing. The symptoms can be understood as follows. First, there is frequently the sudden onset of fear with little provoking stimulus. This leads to a release of
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Bandelow, Borwin; Seidler-Brandler, Ulrich; Becker, Andreas; Wedekind, Dirk; RĂŒther, Eckart (January 2007). "Meta-analysis of randomized controlled comparisons of psychopharmacological and psychological treatments for anxiety disorders".
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Schwartze, Dominique; Barkowski, Sarah; Strauss, Bernhard; Burlingame, Gary M.; Barth, JĂŒrgen; Rosendahl, Jenny (June 2017). "Efficacy of group psychotherapy for panic disorder: Meta-analysis of randomized, controlled trials".
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Kabat-Zinn, J; Massion, AO; Kristeller, J; Peterson, LG; Fletcher, KE; Pbert, L; Lenderking, WR; Santorelli, SF (July 1992). "Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders".
1200:
Increased and regimented aerobic exercise such as running has been shown to have a positive effect on combating panic anxiety. There is evidence that suggests that this effect is correlated to the release of exercise-induced
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for 2 seconds. Then slowly exhale, over 5 seconds. Repeat this cycle twice and then breathe 'normally' for 5 cycles (1 cycle = 1 inhale + 1 exhale). The point is to focus on breathing and relax the heart rate. Regular
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in that panic attacks are often sudden and unprovoked. However, panic attacks experienced by those with panic disorder may also be linked to or heightened by certain places or situations, making daily life difficult.
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There remains a chance of panic symptoms becoming triggered or being made worse due to increased respiration rate that occurs during aerobic exercise. This increased respiration rate can lead to hyperventilation and
533:(ruling out other conditions) must be performed before diagnosing a panic attack. It is especially important to do this for people whose mental health and heart health statuses are unknown. This can be done using an
745:(ÏÏÎČÎżÏ), the term "agora" referring to the city centre in an ancient Greek city. In Japan, people who exhibit extreme agoraphobia to the point of becoming unwilling or unable to leave their homes are referred to as
1362:(MAOIs). SSRIs in particular tend to be the first drug treatment used to treat panic attacks. Selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants appear similar for short-term efficacy.
396:, mostly due to blood flow leaving the head to more critical parts of the body in defense. These feelings may provoke a strong urge to escape or flee the place where the attack began (a consequence of the "
3664:
Shear, M. K.; Rucci, P.; Williams, J.; Frank, E.; Grochocinski, V.; Vander Bilt, J.; Houck, P.; Wang, T. (2001). "Reliability and validity of the Panic
Disorder Severity Scale: Replication and extension".
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In DSM-5, culture-specific symptoms (e.g., tinnitus, neck soreness, headache, and uncontrollable screaming or crying) may be seen. Such symptoms should not count as one of the four required symptoms.
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well-being. Panic disorder often occurs in early adulthood, although it may appear at any age. It occurs more frequently in women and more often in people with above-average intelligence. Various
1397:
In Europe, about 3% of the population has a panic attack in a given year while in the United States they affect about 11%. They are more common in females than in males. They often begin during
360:
In Europe, about 3% of the population has a panic attack in a given year while in the United States they affect about 11%. They are more common in females than in males. They often begin during
1019:(PFC) region of the brain. There is evidence that having an anxiety disorder increases the risk of cardiovascular disease (CVD). Those affected also have a reduction in heart rate variability.
1839:
2610:
685:. Studies report that about 20% to 30% of recreational users experience such problems after smoking marijuana." Cigarette smoking is another substance that has been linked to panic attacks.
833:
An increase of serotonin in certain pathways of the brain seems to be correlated with reduced anxiety. More evidence that suggests serotonin plays a role in anxiety is that people who take
540:
Panic attacks are distinguished from other forms of anxiety by their intensity and their sudden, episodic nature. They are often experienced in conjunction with anxiety disorders and other
283:
diagnosis, course, and comorbidity across an array of disorders, including but not limited to anxiety disorders. Hence, panic attacks can be listed as a specifier that is applicable to all
702:
People who have repeated, persistent attacks or feel severe anxiety about having another attack are said to have panic disorder. Panic disorder is strikingly different from other types of
4273:
Fava, G. A.; Rafanelli, C.; Grandi, S.; Conti, S.; Ruini, C.; Mangelli, L.; Belluardo, P. (July 2001). "Long-term outcome of panic disorder with agoraphobia treated by exposure".
1095:. It is not considered a specific disorder on its own, with the symptoms of a panic attack regarded as characteristics of another disorder during which the panic attack occurs.
3815:
American
Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed., text rev., p. 479). Washington, D.C.: American Psychiatric Association.
1217:, which mimics symptoms of a heart attack, thus inducing a panic attack. The benefits of incorporating an exercise regimen have shown the best results when paced accordingly.
612:
hypochondriacal fears, overcautious view of the world, and cumulative stress have been correlated with panic attacks. In adolescents, social transitions may also be a cause.
2293:
Davies, Matthew N.; Verdi, Serena; Burri, Andrea; Trzaskowski, Maciej; Lee, Minyoung; Hettema, John M.; Jansen, Rick; Boomsma, Dorret I.; Spector, Tim D. (14 August 2015).
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had a panic episode after treatment. They concluded that the use of exposure therapy has lasting efficacy for a client who is living with a panic disorder and agoraphobia.
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1980:
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situations and body sensations, helps weaken anxiety responses to panic-inducing external and internal stimuli and reinforce realistic ways of viewing panic symptoms.
859:
such as tricyclics and SNRIs are effective for the long-term treatment of panic attacks, possibly by blunting the norepinephrine spikes associated with panic attacks.
762:
of these situations and begin to avoid them. Eventually, the pattern of avoidance and level of anxiety about another attack may reach the point where individuals with
1351:
3465:
Soares-Filho, Gastão Luiz; Mesquita, Claudio; Mesquita, Evandro; Arias-Carrión, Oscar; Machado, Sergio; Gonzålez, Manuel; Valença, Alexandre; Nardi, Antonio (2012).
3989:
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Moreira, FabrĂcio A.; Gobira, Pedro H.; Viana, ThĂ©rcia G.; Vicente, Maria A.; Zangrossi, HĂ©lio; Graeff, Frederico G. (2013). "Modeling panic disorder in rodents".
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an abrupt surge of intense fear or intense discomfort that reaches a peak within minutes and during which time four or more of the following symptoms occur":
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Roughly one-third are treatment-resistant. These people continue to have panic attacks and various other panic disorder symptoms after receiving treatment.
4503:
Freire, Rafael C.; Zugliani, Morena M.; Garcia, Rafael F.; Nardi, Antonio E. (22 January 2016). "Treatmentâresistant panic disorder: a systematic review".
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The efficacy of group therapy treatment over conventional individual therapy for people with panic disorder with or without agoraphobia appears similar.
1311:
4549:
Hettema, John M.; Neale, Michael C.; Kendler, Kenneth S. (October 2001). "A Review and Meta-Analysis of the
Genetic Epidemiology of Anxiety Disorders".
2497:
4068:
569:
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Stewart, Julian M.; Pianosi, Paul; Shaban, Mohamed A.; Terilli, Courtney; Svistunova, Maria; Visintainer, Paul; Medow, Marvin S. (1 November 2018).
1828:
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830:. More research into how these neurotransmitters interact with one another during a panic attack is needed to make any solid conclusions, however.
688:
A common denominator of current psychiatric approaches to panic disorder is that no real danger exists, and the person's anxiety is inappropriate.
4037:
Do not use a paper bag in an attempt to treat hyperventilation. These patients can often be cared for with low-flow oxygen and lots of reassurance
851:
that affect dopamine production have been proven to treat anxiety. However, this may be attributed to dopamine's tendency to increase feelings of
678:
3872:
2713:"Severe Social Withdrawal: Cultural Variation in Past Hikikomori Experiences of University Students in Nigeria, Singapore, and the United States"
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Panic attack symptoms can be experimentally induced in the laboratory by various means. Among them, for research purposes, by administering a
681:), can cause a panic attack. According to the Harvard Mental Health Letter, "the most commonly reported side effects of smoking marijuana are
4225:
4030:
3744:
3621:
Houck, P. R.; Spiegel, D. A.; Shear, M. K.; Rucci, P. (2002). "Reliability of the self-report version of the Panic
Disorder Severity Scale".
3323:
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where one identical twin has an anxiety disorder have reported a high incidence of the other twin also having an anxiety disorder diagnosis.
2432:
William T. OâDonohue,· Lorraine T. Benuto, Lauren
Woodward Tolle (eds, 2013). Handbook of Adolescent Health Psychology, Springer, New York.
1780:"International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology"
3599:
1687:
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4178:
4005:
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Bowker, Julie C.; Bowker, Matthew H.; Santo, Jonathan B.; Ojo, Adesola
Adebusola; Etkin, Rebecca G.; Raja, Radhi (3 September 2019).
1866:"Hemodynamic characteristics of postural hyperventilation: POTS with hyperventilation versus panic versus voluntary hyperventilation"
565:
322:
increase the risk of having a panic attack. Before diagnosis, conditions that produce similar symptoms should be ruled out, such as
3944:
3103:"Exaggerated compensatory response to acute respiratory alkalosis in panic disorder is induced by increased lactic acid production"
2150:
2689:
4403:
Bakker, A.; Van Balkom, A. J. L. M.; Spinhoven, P. (2002). "SSRIs vs. TCAs in the treatment of panic disorder: a meta-analysis".
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Maddock, Richard J.; Carter, Cameron S. (May 1991). "Hyperventilation-induced panic attacks in panic disorder with agoraphobia".
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may cause or exacerbate panic anxiety. Anxiety can temporarily increase during withdrawal from caffeine and various other drugs.
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Panic disorder is usually effectively treated with a variety of interventions, including psychological therapies and medication.
3825:
2767:
1972:
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Hyperventilation syndrome may occur when a person breathes from the chest, which can lead to over-breathing (exhaling excessive
4151:
2295:"Generalised Anxiety Disorder â A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression"
1703:
1319:
673:
Panic attacks may also be caused by substances. Discontinuation or marked reduction in the dose of a substance such as a drug (
3708:
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is involved, exacerbating the effects of the panic attack. Breathing retraining exercise helps to rebalance the oxygen and CO
573:
416:
299:
139:
4231:
4175:"Cognitive Restructuring Ability, Teacher Guidance and Perceptual Distracter Tasks: An Aptitude Treatment Interaction Study"
1031:. A panic attack induces significant sympathetic activation, which can cause vasoconstriction of small coronary vessels and
1066:
may exacerbate ischemic pain by increasing myocardial oxygen demand through increased heart rate, blood pressure, coronary
3149:
1701:
Lo, Yu-Chi; Chen, Hsi-Han (May 2020). "Shiau-Shian Huang Panic
Disorder Correlates with the Risk for Sexual Dysfunction".
1167:
751:. The phenomena in general is known by the same name, and it is estimated that roughly half a million Japanese youths are
31:
2114:
Panic
Anxiety and Its Treatments: Report of the World Psychiatric Association Presidential Educational Program Task Force
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1186:. A 2009 review found positive results from therapy and medication and a much better result when the two were combined.
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may be used. Breathing training and muscle relaxation techniques may also help. Those affected are at a higher risk of
2555:
Gorman, JM; Kent, JM; Sullivan, GM; Coplan, JD (April 2000). "Neuroanatomical hypothesis of panic disorder, revised".
400:", in which the hormone causing this response is released in significant amounts). This response floods the body with
658:. This syndrome often involves prominent mouth breathing as well. This causes a cluster of symptoms, including rapid
3750:
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412:
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People will often experience panic attacks as a direct result of exposure to an object/situation that they have a
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are unable to drive or even step out of the house. At this stage, the person is said to have panic disorder with
647:
495:. These physical symptoms are interpreted with alarm in people prone to panic attacks. This results in increased
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147:
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are worried that their panic attacks mean they are "going crazy" or that the panic might induce a heart attack.
4652:
1355:
1036:
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848:
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3467:"Panic attack triggering myocardial ischemia documented by myocardial perfusion imaging study. A case report"
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overdose on. MAOIs are generally suggested for patients who have not responded to other forms of treatment.
1303:
1295:
1252:
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295:
135:
96:
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A Guide to the Standard EMDR Therapy Protocols for Clinicians, Supervisors, and Consultants, Second Edition
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Inglis, Sally C; Clark, Robyn A; Dierckx, Riet; Prieto-Merino, David; Cleland, John GF (31 October 2015).
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can be used to detect possible cases of disorder and suggest the need for a formal diagnostic assessment.
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Some maintaining causes include avoidance of panic-provoking situations or environments, anxious/negative
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521:. Because chest pain and shortness of breath are hallmark symptoms of cardiovascular illnesses, including
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Treatment of panic attacks should be directed at the underlying cause. In those with frequent attacks,
4072:
1385:. These panic attacks are less comprehensive, with fewer than four bodily symptoms being experienced.
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are the predominant symptoms. Many people experiencing a panic attack incorrectly attribute them to a
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627:("what-if" thinking), mistaken beliefs ("these symptoms are harmful and/or dangerous"), and withheld
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along with decreased blood flow and blood sugar in the brain can lead to decreased activity in the
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Hyperventilation Syndrome â Can I treat hyperventilation syndrome by breathing into a paper bag?
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3354:
Chalmers, John A.; Quintana, Daniel S.; Abbott, Maree J.-Anne; Kemp, Andrew H. (11 July 2014).
3054:"Acidâbase dysregulation and chemosensory mechanisms in panic disorder: a translational update"
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2174:"The psychological development of panic disorder: implications for neurobiology and treatment"
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2628:"Structured telephone support or non-invasive telemonitoring for patients with heart failure"
479:(particularly in the hands, which may 'lock up' and become difficult to move), sensations of
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4096:"Hyperventilation in panic disorder and asthma: Empirical evidence and clinical strategies"
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Bergeron, J. David; Le Baudour, Chris (2009). "Chapter 9: Caring for Medical Emergencies".
3940:
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tend to feel a reduction of anxiety when their brain has more serotonin available to use.
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disorder (OCD), and generalized anxiety disorder. The researchers used a database called
1007:
has been suggested to have a critical role. The combination of increased activity in the
4214:
Abramowitz, Jonathan S.; Deacon, Brett J.; Whiteside, Stephen P. H. (17 December 2012).
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Rockville (MD), Substance Abuse and Mental Health Services Administration. (June 2016).
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Derealization (feelings of unreality) or depersonalization (being detached from oneself)
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3356:"Anxiety Disorders are Associated with Reduced Heart Rate Variability: A Meta-Analysis"
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Bystritsky, Alexander; Khalsa, Sahib S.; Cameron, Michael E.; Schiffman, Jason (2013).
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Treating Severe Depressive and Persecutory Anxiety States: To Transform the Unbearable
3968:"Breathing Exercise - A Commanding Tool for Self-help Management during Panic attacks"
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1602:
844:(CNS) is GABA. Most of the pathways that use GABA tend to reduce anxiety immediately.
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3967:
3003:"The noradrenergic paradox: implications in the management of depression and anxiety"
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2012:
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According to the American Psychological Association, "most specialists agree that a
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A depiction of someone experiencing a panic attack being reassured by another person
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3856:
3700:
3592:"Table 3.10, Panic Disorder and Agoraphobia Criteria Changes from DSM-IV to DSM-5"
3001:
Montoya, Alonso; Bruins, Robert; Katzman, Martin A; Blier, Pierre (1 March 2016).
2728:
2081:
1925:"Diversity of effective treatments of panic attacks: what do they have in common?"
4657:
4562:
4215:
2319:
1716:
3851:
2712:
1027:
Panic attacks can cause chest pain by directly affecting the circulation in the
968:
964:
885:
767:
725:
716:
643:
472:
405:
278:
The essential features of panic attacks remain unchanged, although the official
155:
4668:
3272:
3259:
Maren, Stephen (November 2009). "An Acid-Sensing Channel Sows Fear and Panic".
3143:
2568:
1795:
880:
when the body prepares for strenuous physical activity, resulting in increased
4631:
4370:
4353:
4352:
Batelaan, Neeltje M.; Van Balkom, Anton J. L. M.; Stein, Dan J. (April 2012).
4286:
3786:
3525:"Elevated troponin linked to mental stress ischemia in heart disease patients"
2921:
2533:
1274:
1202:
952:
944:
940:
921:
873:
747:
720:
655:
510:
484:
443:, cold flashes, burning sensations (particularly in the facial or neck area),
436:
350:
264:
223:
216:
67:
17:
3492:
3433:
3372:
2822:
2736:
2401:
1891:
3101:
Ueda, Y.; Aizawa, M.; Takahashi, A.; Fujii, M.; Isaka, Y. (8 October 2008).
2798:
1052:
1044:
1012:
988:
956:
827:
811:
790:). Various animal models of panic attacks have been experimentally studied.
663:
624:
452:
440:
420:
381:
377:
310:, and medical problems. They can either be triggered or occur unexpectedly.
233:
101:
4570:
4524:
4486:
4424:
4389:
4294:
4129:
3794:
3686:
3642:
3573:
3510:
3483:
3451:
3391:
3290:
3245:
3128:
3087:
3038:
2987:
2929:
2886:
2830:
2744:
2671:
2576:
2541:
2419:
2338:
2199:
1950:
1909:
1813:
1724:
1610:
1182:
has the most complete and longest duration of effect, followed by specific
3926:
3918:
2471:
1070:, or sympathetic hyperactivity regulated by the autonomic nervous system.
364:
or early adulthood. Children and older people are less commonly affected.
49:
3730:
3425:
3281:
3119:
3102:
2111:
Klerman, Gerald L.; Hirschfeld, Robert M. A.; Weissman, Myrna M. (1993).
1416:
1206:
1194:
1008:
1004:
980:
976:
819:
444:
401:
315:
3227:
4330:
3069:
3019:
1403:
1398:
1326:. Paranoid anxiety may reach the level of a persecutory anxiety state.
893:
807:
628:
496:
480:
456:
424:
361:
354:
311:
160:
105:
4614:
4467:
4380:
3410:"Panic Disorder and Chest Pain: Mechanisms, Morbidity, and Management"
2652:
4626:
4599:
3732:
Generalised anxiety disorder and panic disorder in adults: management
3634:
3408:
Huffman, Jeff C.; Pollack, Mark H.; Stern, Theodore A. (2002-04-01).
1941:
1924:
1264:
759:
758:
People who have had a panic attack in certain situations may develop
742:
639:
616:
544:
conditions, although panic attacks are not generally indicative of a
448:
385:
279:
1827:
American Psychiatric Association, American Psychiatric Association.
1255:
may be achieved by extending the out-breath by counting or humming.
3171:
Nardi, Antonio Egidio; Freire, Rafael Christophe R. (25 May 2016).
1426:
1096:
1088:
909:
787:
738:
476:
284:
1589:
Craske, Michelle G; Stein, Murray B (December 2016). "Anxiety".
1381:
Many people being treated for panic attacks begin to experience
1039:
activation and hyperventilation during panic attacks may induce
905:
834:
815:
256:
80:
2034:"Panic attack symptoms - What are the signs of a panic attack?"
1525:
Diagnostic and Statistical Manual of Mental Disorders (5th ed.)
896:), and sweating. Because strenuous activity rarely ensues, the
608:, an area of the brain stem, has been linked to panic attacks.
4025:(8 ed.). New Jersey: Pearson Prentice Hall. p. 262.
3972:
Research Journal of Pharmacy and Technology, 10(12), 4471-4473
1555:
Bandelow, Borwin; Domschke, Katharina; Baldwin, David (2013).
4354:"Evidence-based pharmacotherapy of panic disorder: an update"
2799:"Diagnosis and treatment of agoraphobia with panic disorder"
1105:
3212:"The Neurocircuitry of Fear, Stress, and Anxiety Disorders"
933:
913:
290:
Panic attacks can occur due to several disorders including
3966:
Bhagat, Vidya; Haque2, Mainul; Jaalam3, Kamarudin (2017).
372:
People with panic attacks often report a fear of dying or
1670:
Geddes, John; Price, Jonathan; McKnight, Rebecca (2012).
1302:
In deeper-level psychoanalytic approaches, in particular
847:
Dopamine's role in anxiety is not well understood. Some
388:, numbness throughout the body, shortness of breath and
1528:, Arlington: American Psychiatric Publishing, pp.
1341:
Medication options for panic attacks typically include
392:, or loss of body control. Some people also experience
2962:"Current Diagnosis and Treatment of Anxiety Disorders"
2797:
Perugi, Giulio; Frare, Franco; Toni, Cristina (2007).
408:(adrenaline), which aid it in defending against harm.
4217:
Exposure Therapy for Anxiety: Principles and Practice
4173:
Cramer, K., Post, T., & Behr, M. (January 1989).
3174:
Panic Disorder: Neurobiological and Treatment Aspects
2213:
Marquardt, David Z. Hambrick, Madeline (March 2018).
4604:
4358:
The International Journal of Neuropsychopharmacology
1120:
Sensations of shortness of breath or being smothered
411:
A panic attack can result when up-regulation by the
4608:
2768:"Why won't 541,000 young Japanese leave the house?"
1746:Smith, Melinda; Robinson, Lawrence; Segal, Jeanne.
1220:Meditation may also be helpful in the treatment of
1205:and the subsequent reduction of the stress hormone
242:
232:
222:
208:
180:
170:
154:
127:
119:
111:
95:
73:
61:
42:
3701:"Panic disorder: MedlinePlus Medical Encyclopedia"
2082:"Panic disorder: MedlinePlus Medical Encyclopedia"
1263:and so reduces symptoms, it may excessively lower
1091:a panic attack is part of the diagnostic class of
855:and confidence, which indirectly reduces anxiety.
802:are affected when the body is under the increased
3737:National Institute for Health and Care Excellence
2494:"Medical marijuana and the mind - Harvard Health"
2379:
2377:
2375:
2373:
1291:combination of cognitive and behavioral therapies
892:) which may be perceived as shortness of breath (
4144:"Answers to Your Questions About Panic Disorder"
4094:Meuret, Alicia E.; Ritz, Thomas (October 2010).
1350:), serotonin noradrenaline reuptake inhibitors (
936:shift into autonomic and respiratory responses.
4544:
4542:
4498:
4496:
4444:
4442:
4268:
4266:
3546:
3544:
3349:
3347:
3210:Shin, Lisa M; Liberzon, Israel (January 2010).
1306:, panic attacks are frequently associated with
4451:"Pharmacological management of panic disorder"
4319:Group Dynamics: Theory, Research, and Practice
3052:Vollmer, L L; Strawn, J R; Sah, R (May 2015).
1148:Paresthesias (numbness or tingling sensations)
1136:Feeling dizzy, unsteady, lightheaded, or faint
733:place". The word "agoraphobia" comes from the
3826:"3 Tips for Using Exercise to Shrink Anxiety"
3554:CNS & Neurological Disorders Drug Targets
2008:
2006:
2004:
2002:
2000:
1998:
8:
4199:: CS1 maint: multiple names: authors list (
3414:The Primary Care Companion for CNS Disorders
2522:Experimental and Clinical Psychopharmacology
2243:: CS1 maint: multiple names: authors list (
2117:. American Psychiatric Association. p.
1584:
1582:
840:The main inhibitory neurotransmitter in the
810:that accompany a panic attack. Some include
3988:: CS1 maint: numeric names: authors list (
1318:. They are often found to be comorbid with
1111:Palpitations, and/or accelerated heart rate
1099:criteria for a panic attack is defined as "
4605:
3775:The World Journal of Biological Psychiatry
1550:
1548:
1312:paranoid-schizoid and depressive positions
48:
39:
4476:
4466:
4379:
4369:
4119:
4100:International Journal of Psychophysiology
3908:
3500:
3482:
3441:
3381:
3371:
3280:
3235:
3118:
3077:
3028:
3018:
2977:
2955:
2953:
2951:
2949:
2947:
2865:Cholecystokinin-Tetrapeptide in Humans".
2661:
2651:
2409:
2328:
2318:
2189:
2143:"Panic Disorder | Anxiety and Depression"
1940:
1899:
1881:
1803:
1665:
1663:
1661:
1630:
1628:
1522:American Psychiatric Association (2013),
1444:
1442:
1051:and cardiac chest pain, despite a normal
570:postural orthostatic tachycardia syndrome
3312:PhD, Andrew M. Leeds (3 February 2016).
884:. This results in increased heart rate (
419:(PNS). The most common symptoms include
3148:. Morgan & Claypool Life Sciences.
2632:Cochrane Database of Systematic Reviews
2258:Gregory a. Leskin, PhD (January 2004).
1517:
1515:
1513:
1511:
1509:
1507:
1505:
1503:
1501:
1499:
1497:
1495:
1438:
1184:selective serotonin reuptake inhibitors
679:antidepressant discontinuation syndrome
4455:Neuropsychiatric Disease and Treatment
4192:
4067:Craske, Michelle (30 September 2011).
3981:
3152:from the original on 28 September 2020
3007:Neuropsychiatric Disease and Treatment
2260:"Gender Differences in Panic Disorder"
2236:
1829:"Changes to the DSM-V to the DSM-V-TR"
1636:"Panic Disorder: When Fear Overwhelms"
1575:from the original on 20 December 2016.
1493:
1491:
1489:
1487:
1485:
1483:
1481:
1479:
1477:
1475:
1460:from the original on 29 September 2016
1142:Fear of losing control or going insane
4181:from the original on 22 December 2010
3753:from the original on 22 November 2018
3585:
3583:
3403:
3401:
3332:from the original on 30 December 2023
3191:from the original on 30 December 2023
2845:from the original on 24 February 2021
2215:"Bad News for the Highly Intelligent"
1845:from the original on 2 September 2018
876:(epinephrine) which brings about the
7:
4154:from the original on 10 January 2021
2274:from the original on 23 January 2021
2225:from the original on 27 January 2021
1690:from the original on 4 October 2016.
975:suggests heightened activity in the
176:After other possible causes excluded
4003:Breathing in and out of a paper bag
3107:Nephrology Dialysis Transplantation
2500:from the original on 21 August 2016
1973:"Symptoms and causes - Mayo Clinic"
677:), for example, an antidepressant (
670:, which can trigger panic attacks.
4148:American Psychological Association
4069:"Psychotherapy for panic disorder"
3875:from the original on 23 April 2015
3832:from the original on 20 April 2015
3471:International Archives of Medicine
2766:Emiko Jozuka (12 September 2016).
2557:The American Journal of Psychiatry
2153:from the original on 12 March 2023
1983:from the original on 17 March 2022
1748:"Panic Attacks and Panic Disorder"
1646:from the original on 23 March 2022
1281:levels, may help guide breathing.
25:
4505:Expert Opinion on Pharmacotherapy
4234:from the original on 20 May 2016.
3947:from the original on 13 July 2017
3602:from the original on 7 March 2023
3566:10.2174/1871527313666140612141500
2778:from the original on 6 March 2021
2717:The Journal of Genetic Psychology
2692:from the original on 24 June 2012
2688:. MayoClinic.com. 21 April 2011.
2590:Panic Disorder â familydoctor.org
2266:. Psychiatric Times Vol 21 No 1.
2178:Revista Brasileira de Psiquiatria
1561:. OUP Oxford. p. Chapter 1.
1049:ischemic damage to the myocardium
4417:10.1034/j.1600-0447.2002.02255.x
3711:from the original on 8 June 2023
2815:10.2165/00023210-200721090-00004
2384:Taylor, C Barr (22 April 2006).
2092:from the original on 8 June 2023
2058:"How Anxiety Affects Your Hands"
1923:Roth, Walton T. (January 2010).
1836:Changes to the DSM V to DSM V-TR
1758:from the original on 9 July 2021
1236:In the great majority of cases,
912:. This leads to shifts in blood
259:and discomfort that may include
3869:"Cardio Exercise for Beginners"
3667:Journal of Psychiatric Research
3318:. Springer Publishing Company.
2191:10.1590/s1516-44462012000500003
2017:The Anxiety and Phobia Workbook
1883:10.1152/japplphysiol.00377.2018
1704:Journal of Psychiatric Practice
1320:borderline personality disorder
932:mechanisms that translate this
537:and mental health assessments.
475:(tingling sensations), intense
4551:American Journal of Psychiatry
4449:Marchesi, Carlo (March 2008).
4405:Acta Psychiatrica Scandinavica
4112:10.1016/j.ijpsycho.2010.05.006
3897:American Journal of Psychiatry
3145:Control of Cerebral Blood Flow
2879:10.1016/j.biopsych.2012.09.004
2644:10.1002/14651858.CD007228.pub3
2352:Nolen-Hoeksema, Susan (2013).
2172:Cosci, Fiammetta (June 2012).
1558:Panic Disorder and Agoraphobia
1047:). This process may result in
971:and toward the major muscles.
786:cholecystokinin-tetrapeptide (
596:, and inner ear disturbances (
574:post-traumatic stress disorder
564:Biological causes may include
517:and thus seek treatment in an
417:parasympathetic nervous system
415:(SNS) is not moderated by the
380:or other visual disturbances,
300:post-traumatic stress disorder
255:are sudden periods of intense
140:post-traumatic stress disorder
1:
4517:10.1517/14656566.2016.1109628
3679:10.1016/S0022-3956(01)00028-0
2729:10.1080/00221325.2019.1633618
2356:(6th ed.). McGraw Hill.
1870:Journal of Applied Physiology
1603:10.1016/S0140-6736(16)30381-6
1168:Panic Disorder Severity Scale
566:obsessive-compulsive disorder
32:Panic attack (disambiguation)
4563:10.1176/appi.ajp.158.10.1568
3142:Cipolla, Marilyn J. (2009).
2464:10.1016/0006-3223(91)90051-m
2320:10.1371/journal.pone.0134865
1717:10.1097/PRA.0000000000000460
1180:Cognitive-behavioral therapy
1166:Screening tools such as the
1129:Nausea or abdominal distress
947:during a panic attack cause
863:elimination of those fears.
3941:"Hyperventilation Syndrome"
1676:. OUP Oxford. p. 298.
1277:, which provides exhaled CO
963:. A panic attack can cause
951:resulting in slightly less
818:(gamma-aminobutyric acid),
794:Neurotransmitter imbalances
4707:
3735:. Clinical Guideline 113.
3273:10.1016/j.cell.2009.11.008
2569:10.1176/appi.ajp.157.4.493
967:to be drawn away from the
714:
695:
413:sympathetic nervous system
29:
4371:10.1017/S1461145711000800
4287:10.1017/s0033291701003592
3787:10.1080/15622970601110273
2966:Pharmacy and Therapeutics
2922:10.1007/s00441-013-1610-1
2534:10.1037/1064-1297.16.1.66
1356:tricyclic antidepressants
1215:hyperventilation syndrome
1151:Chills or heat sensations
955:to the head which causes
849:antipsychotic medications
683:anxiety and panic attacks
648:Hyperventilation syndrome
638:related to the amount of
56:
47:
3852:MedlinePlus Encyclopedia
3373:10.3389/fpsyt.2014.00080
3058:Translational Psychiatry
2910:Cell and Tissue Research
2402:10.1136/bmj.332.7547.951
1796:10.1093/eurheartj/ehy076
1126:Chest pain or discomfort
1037:Autonomic nervous system
924:), causing compensatory
878:fight-or-flight response
600:). Dysregulation of the
398:fight-or-flight response
271:, trembling, dizziness,
4054:20 January 2013 at the
4008:21 October 2007 at the
3360:Frontiers in Psychiatry
3216:Neuropsychopharmacology
2595:3 February 2014 at the
1383:limited symptom attacks
1304:object relations theory
1296:Cognitive restructuring
1253:diaphragmatic breathing
1145:Sense of impending doom
1060:coronary artery disease
296:social anxiety disorder
136:social anxiety disorder
4275:Psychological Medicine
4245:Waska, Robert (2010).
3623:Depression and Anxiety
3484:10.1186/1755-7682-5-24
1929:Depression and Anxiety
1784:European Heart Journal
1308:splitting (psychology)
1074:Cardiovascular disease
991:regions including the
842:central nervous system
774:Experimentally induced
531:diagnosis of exclusion
439:(or chest tightness),
304:substance use disorder
182:Differential diagnosis
27:Period of intense fear
3919:10.1176/ajp.149.7.936
2867:Biological Psychiatry
2613:12 April 2014 at the
2452:Biological Psychiatry
2354:(Ab)normal Psychology
1244:levels in the blood.
1041:coronary artery spasm
1003:. In particular, the
918:respiratory alkalosis
652:respiratory alkalosis
602:norepinephrine system
590:mitral valve prolapse
527:myocardial infarction
487:, difficulty moving,
267:or chest discomfort,
87:, sweating, shaking,
3943:. 28 November 2016.
3596:www.ncbi.nlm.nih.gov
3426:10.4088/PCC.v04n0203
1597:(10063): 3048â3059.
1117:Trembling or shaking
1064:psychological stress
1062:, panic attacks and
1058:In individuals with
1033:microvascular angina
1029:coronary vasculature
997:parabrachial nucleus
888:), rapid breathing (
320:psychological stress
165:psychological stress
30:For other uses, see
3228:10.1038/npp.2009.83
2608:"Anxiety Disorders"
2311:2015PLoSO..1034865D
2219:Scientific American
2021:New Harbinger Press
1450:"Anxiety Disorders"
1232:Breathing exercises
993:periaqueductal gray
900:leads to a drop in
507:Shortness of breath
429:shortness of breath
328:hyperparathyroidism
269:shortness of breath
191:hyperparathyroidism
89:shortness of breath
79:Periods of intense
4331:10.1037/gdn0000064
4220:. Guilford Press.
4075:on 14 October 2017
3120:10.1093/ndt/gfn585
3070:10.1038/tp.2015.67
3020:10.2147/NDT.S91311
2062:www.calmclinic.com
1977:www.mayoclinic.org
1324:child sexual abuse
1123:Feeling of choking
1011:(fear center) and
926:metabolic acidosis
529:(heart attack), a
433:heart palpitations
368:Signs and symptoms
150:, medical problems
4678:
4677:
4557:(10): 1568â1578.
4468:10.2147/ndt.s1557
4227:978-1-4625-0969-0
4032:978-0-13-614059-7
3746:978-1-4731-2854-5
3325:978-0-8261-3117-1
3184:978-3-319-12538-1
2438:978-1-4614-6632-1
2396:(7547): 951â955.
2363:978-0-07-803538-8
2264:Psychiatric Times
2128:978-0-88048-684-2
1790:(22): 2032â2046.
1683:978-0-19-923396-0
1568:978-0-19-100426-1
1539:978-0-89042-555-8
1422:Nervous breakdown
1259:increases needed
1190:Lifestyle changes
1160:
1159:
1093:anxiety disorders
1087:According to the
1023:Cardiac mechanism
1017:prefrontal cortex
800:neurotransmitters
782:injection of the
704:anxiety disorders
535:electrocardiogram
501:positive feedback
489:depersonalization
250:
249:
246:3% (EU), 11% (US)
172:Diagnostic method
37:Medical condition
16:(Redirected from
4698:
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4393:
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4343:
4342:
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4260:
4249:. Karnac Books.
4242:
4236:
4235:
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4205:
4204:
4198:
4190:
4188:
4186:
4170:
4164:
4163:
4161:
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4080:
4071:. Archived from
4064:
4058:
4046:
4040:
4039:
4018:
4012:
4000:
3994:
3993:
3987:
3979:
3978:(12): 4471â4473.
3963:
3957:
3956:
3954:
3952:
3937:
3931:
3930:
3912:
3891:
3885:
3884:
3882:
3880:
3865:
3859:
3857:Hyperventilation
3848:
3842:
3841:
3839:
3837:
3828:. 17 July 2013.
3822:
3816:
3813:
3807:
3806:
3769:
3763:
3762:
3760:
3758:
3739:. 26 July 2019.
3727:
3721:
3720:
3718:
3716:
3697:
3691:
3690:
3661:
3655:
3654:
3635:10.1002/da.10049
3618:
3612:
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3538:
3536:
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2708:
2702:
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2697:
2682:
2676:
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2665:
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2638:(10): CD007228.
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2516:
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2507:
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2386:"Panic disorder"
2381:
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2204:
2203:
2193:
2169:
2163:
2162:
2160:
2158:
2139:
2133:
2132:
2108:
2102:
2101:
2099:
2097:
2078:
2072:
2071:
2069:
2068:
2054:
2048:
2047:
2045:
2044:
2038:www.avogel.co.uk
2030:
2024:
2010:
1993:
1992:
1990:
1988:
1969:
1963:
1962:
1944:
1942:10.1002/da.20601
1920:
1914:
1913:
1903:
1885:
1876:(5): 1396â1403.
1861:
1855:
1854:
1852:
1850:
1844:
1833:
1824:
1818:
1817:
1807:
1774:
1768:
1767:
1765:
1763:
1743:
1737:
1736:
1698:
1692:
1691:
1667:
1656:
1655:
1653:
1651:
1632:
1623:
1622:
1586:
1577:
1576:
1552:
1543:
1542:
1519:
1470:
1469:
1467:
1465:
1446:
1316:paranoid anxiety
1238:hyperventilation
1106:
949:vasoconstriction
908:and then in the
898:hyperventilation
890:hyperventilation
882:sympathetic tone
730:anxiety disorder
594:pheochromocytoma
586:Wilson's disease
469:hyperventilation
465:heavy-headedness
461:light-headedness
390:hyperventilation
338:, drug use, and
123:Seconds to hours
52:
40:
21:
4706:
4705:
4701:
4700:
4699:
4697:
4696:
4695:
4681:
4680:
4679:
4674:
4673:
4617:
4592:
4587:
4586:
4548:
4547:
4540:
4502:
4501:
4494:
4448:
4447:
4440:
4402:
4401:
4397:
4351:
4350:
4346:
4315:
4314:
4310:
4272:
4271:
4264:
4257:
4244:
4243:
4239:
4228:
4213:
4212:
4208:
4191:
4184:
4182:
4172:
4171:
4167:
4157:
4155:
4142:
4141:
4137:
4093:
4092:
4088:
4078:
4076:
4066:
4065:
4061:
4056:Wayback Machine
4047:
4043:
4033:
4023:First Responder
4020:
4019:
4015:
4010:Wayback Machine
4001:
3997:
3980:
3965:
3964:
3960:
3950:
3948:
3939:
3938:
3934:
3910:10.1.1.474.4968
3893:
3892:
3888:
3878:
3876:
3867:
3866:
3862:
3849:
3845:
3835:
3833:
3824:
3823:
3819:
3814:
3810:
3771:
3770:
3766:
3756:
3754:
3747:
3729:
3728:
3724:
3714:
3712:
3705:medlineplus.gov
3699:
3698:
3694:
3663:
3662:
3658:
3620:
3619:
3615:
3605:
3603:
3589:
3588:
3581:
3560:(6): 992â1001.
3550:
3549:
3542:
3533:
3531:
3523:
3522:
3518:
3464:
3463:
3459:
3407:
3406:
3399:
3353:
3352:
3345:
3335:
3333:
3326:
3311:
3310:
3306:
3258:
3257:
3253:
3209:
3208:
3204:
3194:
3192:
3185:
3170:
3169:
3165:
3155:
3153:
3141:
3140:
3136:
3100:
3099:
3095:
3051:
3050:
3046:
3000:
2999:
2995:
2959:
2958:
2945:
2907:
2906:
2902:
2863:
2862:
2858:
2848:
2846:
2796:
2795:
2791:
2781:
2779:
2765:
2764:
2760:
2710:
2709:
2705:
2695:
2693:
2684:
2683:
2679:
2625:
2624:
2620:
2615:Wayback Machine
2606:
2602:
2597:Wayback Machine
2588:
2584:
2554:
2553:
2549:
2518:
2517:
2513:
2503:
2501:
2492:
2491:
2487:
2449:
2448:
2444:
2431:
2427:
2383:
2382:
2371:
2364:
2351:
2350:
2346:
2305:(8): e0134865.
2292:
2291:
2287:
2277:
2275:
2257:
2256:
2252:
2235:
2228:
2226:
2212:
2211:
2207:
2171:
2170:
2166:
2156:
2154:
2141:
2140:
2136:
2129:
2110:
2109:
2105:
2095:
2093:
2086:medlineplus.gov
2080:
2079:
2075:
2066:
2064:
2056:
2055:
2051:
2042:
2040:
2032:
2031:
2027:
2019:, 4th Edition:
2011:
1996:
1986:
1984:
1971:
1970:
1966:
1922:
1921:
1917:
1863:
1862:
1858:
1848:
1846:
1842:
1831:
1826:
1825:
1821:
1776:
1775:
1771:
1761:
1759:
1745:
1744:
1740:
1700:
1699:
1695:
1684:
1669:
1668:
1659:
1649:
1647:
1634:
1633:
1626:
1588:
1587:
1580:
1569:
1554:
1553:
1546:
1540:
1521:
1520:
1473:
1463:
1461:
1448:
1447:
1440:
1435:
1413:
1395:
1376:
1343:benzodiazepines
1339:
1287:
1280:
1243:
1234:
1222:panic disorders
1192:
1176:
1161:
1085:
1076:
1025:
1001:Locus coeruleus
961:lightheadedness
943:and release of
939:Moreover, this
869:
867:Pathophysiology
796:
776:
723:
715:Main articles:
713:
700:
694:
675:drug withdrawal
668:lightheadedness
606:locus coeruleus
582:hyperthyroidism
554:
546:mental disorder
523:unstable angina
404:, particularly
378:flashing vision
370:
324:hyperthyroidism
187:Hyperthyroidism
38:
35:
28:
23:
22:
15:
12:
11:
5:
4704:
4702:
4694:
4693:
4683:
4682:
4676:
4675:
4672:
4671:
4660:
4649:
4634:
4618:
4613:
4612:
4610:
4609:Classification
4603:
4602:
4591:
4590:External links
4588:
4585:
4584:
4538:
4511:(2): 159â168.
4492:
4438:
4411:(3): 163â167.
4395:
4364:(3): 403â415.
4344:
4308:
4281:(5): 891â898.
4262:
4256:978-1855757202
4255:
4237:
4226:
4206:
4165:
4135:
4086:
4059:
4041:
4031:
4013:
3995:
3958:
3932:
3903:(7): 936â943.
3886:
3860:
3843:
3817:
3808:
3781:(3): 175â187.
3764:
3745:
3722:
3692:
3673:(5): 293â296.
3656:
3629:(4): 183â185.
3613:
3579:
3540:
3516:
3457:
3397:
3343:
3324:
3304:
3267:(5): 867â869.
3251:
3222:(1): 169â191.
3202:
3183:
3163:
3134:
3113:(3): 825â828.
3093:
3044:
2993:
2943:
2900:
2856:
2809:(9): 741â764.
2789:
2758:
2703:
2677:
2618:
2600:
2582:
2563:(4): 493â505.
2547:
2511:
2485:
2458:(9): 843â854.
2442:
2425:
2369:
2362:
2344:
2285:
2250:
2205:
2164:
2134:
2127:
2103:
2073:
2049:
2025:
1994:
1964:
1915:
1856:
1819:
1769:
1738:
1711:(3): 185â200.
1693:
1682:
1657:
1624:
1578:
1567:
1544:
1538:
1471:
1456:. March 2016.
1437:
1436:
1434:
1431:
1430:
1429:
1424:
1419:
1412:
1409:
1394:
1391:
1375:
1372:
1360:MAO inhibitors
1338:
1335:
1286:
1283:
1278:
1267:levels in the
1261:carbon dioxide
1248:David D. Burns
1241:
1233:
1230:
1191:
1188:
1175:
1172:
1158:
1157:
1153:
1152:
1149:
1146:
1143:
1140:
1137:
1132:
1131:
1130:
1127:
1124:
1121:
1118:
1115:
1112:
1104:
1084:
1081:
1075:
1072:
1068:vasomotor tone
1024:
1021:
904:levels in the
902:carbon dioxide
868:
865:
824:norepinephrine
795:
792:
775:
772:
764:panic disorder
712:
709:
698:Panic disorder
696:Main article:
693:
692:Panic disorder
690:
636:carbon dioxide
553:
550:
519:emergency room
369:
366:
292:panic disorder
248:
247:
244:
240:
239:
236:
230:
229:
228:Antidepressant
226:
220:
219:
210:
206:
205:
184:
178:
177:
174:
168:
167:
158:
152:
151:
132:Panic disorder
129:
125:
124:
121:
117:
116:
113:
109:
108:
99:
93:
92:
77:
71:
70:
65:
59:
58:
54:
53:
45:
44:
36:
26:
24:
18:Anxiety attack
14:
13:
10:
9:
6:
4:
3:
2:
4703:
4692:
4689:
4688:
4686:
4670:
4666:
4665:
4661:
4659:
4655:
4654:
4650:
4648:
4644:
4643:
4639:
4635:
4633:
4629:
4628:
4624:
4620:
4619:
4616:
4611:
4607:
4601:
4597:
4594:
4593:
4589:
4580:
4576:
4572:
4568:
4564:
4560:
4556:
4552:
4545:
4543:
4539:
4534:
4530:
4526:
4522:
4518:
4514:
4510:
4506:
4499:
4497:
4493:
4488:
4484:
4479:
4474:
4469:
4464:
4461:(1): 93â106.
4460:
4456:
4452:
4445:
4443:
4439:
4434:
4430:
4426:
4422:
4418:
4414:
4410:
4406:
4399:
4396:
4391:
4387:
4382:
4377:
4372:
4367:
4363:
4359:
4355:
4348:
4345:
4340:
4336:
4332:
4328:
4324:
4320:
4312:
4309:
4304:
4300:
4296:
4292:
4288:
4284:
4280:
4276:
4269:
4267:
4263:
4258:
4252:
4248:
4241:
4238:
4233:
4229:
4223:
4219:
4218:
4210:
4207:
4202:
4196:
4180:
4176:
4169:
4166:
4153:
4149:
4145:
4139:
4136:
4131:
4127:
4122:
4117:
4113:
4109:
4105:
4101:
4097:
4090:
4087:
4074:
4070:
4063:
4060:
4057:
4053:
4050:
4045:
4042:
4038:
4034:
4028:
4024:
4017:
4014:
4011:
4007:
4004:
3999:
3996:
3991:
3985:
3977:
3973:
3969:
3962:
3959:
3946:
3942:
3936:
3933:
3928:
3924:
3920:
3916:
3911:
3906:
3902:
3898:
3890:
3887:
3874:
3870:
3864:
3861:
3858:
3854:
3853:
3847:
3844:
3831:
3827:
3821:
3818:
3812:
3809:
3804:
3800:
3796:
3792:
3788:
3784:
3780:
3776:
3768:
3765:
3752:
3748:
3742:
3738:
3734:
3733:
3726:
3723:
3710:
3706:
3702:
3696:
3693:
3688:
3684:
3680:
3676:
3672:
3668:
3660:
3657:
3652:
3648:
3644:
3640:
3636:
3632:
3628:
3624:
3617:
3614:
3601:
3597:
3593:
3586:
3584:
3580:
3575:
3571:
3567:
3563:
3559:
3555:
3547:
3545:
3541:
3530:
3526:
3520:
3517:
3512:
3508:
3503:
3498:
3494:
3490:
3485:
3480:
3476:
3472:
3468:
3461:
3458:
3453:
3449:
3444:
3439:
3435:
3431:
3427:
3423:
3419:
3415:
3411:
3404:
3402:
3398:
3393:
3389:
3384:
3379:
3374:
3369:
3365:
3361:
3357:
3350:
3348:
3344:
3331:
3327:
3321:
3317:
3316:
3308:
3305:
3300:
3296:
3292:
3288:
3283:
3282:2027.42/83231
3278:
3274:
3270:
3266:
3262:
3255:
3252:
3247:
3243:
3238:
3233:
3229:
3225:
3221:
3217:
3213:
3206:
3203:
3190:
3186:
3180:
3176:
3175:
3167:
3164:
3151:
3147:
3146:
3138:
3135:
3130:
3126:
3121:
3116:
3112:
3108:
3104:
3097:
3094:
3089:
3085:
3080:
3075:
3071:
3067:
3063:
3059:
3055:
3048:
3045:
3040:
3036:
3031:
3026:
3021:
3016:
3012:
3008:
3004:
2997:
2994:
2989:
2985:
2980:
2975:
2971:
2967:
2963:
2956:
2954:
2952:
2950:
2948:
2944:
2939:
2935:
2931:
2927:
2923:
2919:
2916:(1): 119â25.
2915:
2911:
2904:
2901:
2896:
2892:
2888:
2884:
2880:
2876:
2873:(4): 337â44.
2872:
2868:
2860:
2857:
2844:
2840:
2836:
2832:
2828:
2824:
2820:
2816:
2812:
2808:
2804:
2800:
2793:
2790:
2777:
2773:
2769:
2762:
2759:
2754:
2750:
2746:
2742:
2738:
2734:
2730:
2726:
2722:
2718:
2714:
2707:
2704:
2691:
2687:
2686:"Agoraphobia"
2681:
2678:
2673:
2669:
2664:
2659:
2654:
2649:
2645:
2641:
2637:
2633:
2629:
2622:
2619:
2616:
2612:
2609:
2604:
2601:
2598:
2594:
2591:
2586:
2583:
2578:
2574:
2570:
2566:
2562:
2558:
2551:
2548:
2543:
2539:
2535:
2531:
2527:
2523:
2515:
2512:
2499:
2495:
2489:
2486:
2481:
2477:
2473:
2469:
2465:
2461:
2457:
2453:
2446:
2443:
2439:
2435:
2429:
2426:
2421:
2417:
2412:
2407:
2403:
2399:
2395:
2391:
2387:
2380:
2378:
2376:
2374:
2370:
2365:
2359:
2355:
2348:
2345:
2340:
2336:
2331:
2326:
2321:
2316:
2312:
2308:
2304:
2300:
2296:
2289:
2286:
2273:
2269:
2265:
2261:
2254:
2251:
2246:
2240:
2224:
2220:
2216:
2209:
2206:
2201:
2197:
2192:
2187:
2183:
2179:
2175:
2168:
2165:
2152:
2148:
2144:
2138:
2135:
2130:
2124:
2120:
2116:
2115:
2107:
2104:
2091:
2087:
2083:
2077:
2074:
2063:
2059:
2053:
2050:
2039:
2035:
2029:
2026:
2022:
2018:
2014:
2009:
2007:
2005:
2003:
2001:
1999:
1995:
1982:
1978:
1974:
1968:
1965:
1960:
1956:
1952:
1948:
1943:
1938:
1934:
1930:
1926:
1919:
1916:
1911:
1907:
1902:
1897:
1893:
1889:
1884:
1879:
1875:
1871:
1867:
1860:
1857:
1841:
1837:
1830:
1823:
1820:
1815:
1811:
1806:
1801:
1797:
1793:
1789:
1785:
1781:
1773:
1770:
1757:
1753:
1749:
1742:
1739:
1734:
1730:
1726:
1722:
1718:
1714:
1710:
1706:
1705:
1697:
1694:
1689:
1685:
1679:
1675:
1674:
1666:
1664:
1662:
1658:
1645:
1641:
1637:
1631:
1629:
1625:
1620:
1616:
1612:
1608:
1604:
1600:
1596:
1592:
1585:
1583:
1579:
1574:
1570:
1564:
1560:
1559:
1551:
1549:
1545:
1541:
1535:
1531:
1527:
1526:
1518:
1516:
1514:
1512:
1510:
1508:
1506:
1504:
1502:
1500:
1498:
1496:
1494:
1492:
1490:
1488:
1486:
1484:
1482:
1480:
1478:
1476:
1472:
1459:
1455:
1451:
1445:
1443:
1439:
1432:
1428:
1425:
1423:
1420:
1418:
1415:
1414:
1410:
1408:
1405:
1400:
1392:
1390:
1386:
1384:
1379:
1373:
1371:
1367:
1363:
1361:
1357:
1353:
1349:
1344:
1336:
1334:
1331:
1327:
1325:
1321:
1317:
1313:
1309:
1305:
1300:
1297:
1292:
1284:
1282:
1276:
1272:
1270:
1266:
1262:
1256:
1254:
1249:
1245:
1239:
1231:
1229:
1225:
1223:
1218:
1216:
1210:
1208:
1204:
1198:
1196:
1189:
1187:
1185:
1181:
1173:
1171:
1169:
1164:
1156:
1150:
1147:
1144:
1141:
1138:
1135:
1134:
1133:
1128:
1125:
1122:
1119:
1116:
1113:
1110:
1109:
1108:
1107:
1103:
1102:
1098:
1094:
1090:
1082:
1080:
1073:
1071:
1069:
1065:
1061:
1056:
1054:
1050:
1046:
1042:
1038:
1034:
1030:
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499:and forms a
473:paresthesias
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374:heart attack
371:
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344:
340:dysautonomia
336:lung disease
289:
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263:, sweating,
261:palpitations
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251:
238:Usually good
203:dysautonomia
201:, drug use,
199:lung disease
156:Risk factors
115:Over minutes
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4185:19 November
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1269:bloodstream
965:blood sugar
928:activating
886:tachycardia
768:agoraphobia
726:Agoraphobia
717:Agoraphobia
711:Agoraphobia
644:bloodstream
455:(or slight
441:hot flashes
406:epinephrine
351:medications
287:disorders.
217:medications
213:Counselling
112:Usual onset
4664:DiseasesDB
4381:1871/42311
3534:2024-04-16
3336:27 October
3195:27 October
2849:3 February
2782:26 January
2653:2328/35732
2440:. Page 511
2278:26 January
2229:26 January
2067:2024-05-23
2043:2024-05-23
2013:Bourne, E.
1673:Psychiatry
1591:The Lancet
1433:References
1337:Medication
1275:Capnometry
1203:endorphins
953:blood flow
945:adrenaline
941:hypocapnia
922:hypocapnia
874:adrenaline
753:Hikikomori
748:Hikikomori
721:Hikikomori
656:hypocapnia
650:can cause
511:chest pain
485:smothering
437:chest pain
347:counseling
308:depression
265:chest pain
224:Medication
148:depression
91:, numbness
68:Psychiatry
4339:152168481
4158:8 January
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3757:8 January
3493:1755-7682
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1892:8750-7587
1752:HelpGuide
1733:218643956
1619:208789585
1464:1 October
1374:Prognosis
1174:Treatment
1083:Diagnosis
1053:angiogram
1045:vasospasm
1013:brainstem
989:brainstem
957:dizziness
828:glutamate
812:serotonin
664:dizziness
660:heartbeat
642:in one's
625:self-talk
453:dizziness
421:trembling
382:faintness
243:Frequency
234:Prognosis
209:Treatment
102:Self-harm
63:Specialty
4685:Category
4571:11578982
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4295:11459386
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2272:Archived
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1951:20049938
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1725:32421290
1688:Archived
1650:18 March
1644:Archived
1642:. 2022.
1611:27349358
1573:Archived
1458:Archived
1417:Hysteria
1411:See also
1207:cortisol
1195:Caffeine
1114:Sweating
1009:amygdala
1005:amygdala
981:thalamus
977:amygdala
820:dopamine
629:feelings
445:sweating
402:hormones
316:caffeine
273:numbness
144:drug use
120:Duration
75:Symptoms
4691:Anxiety
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2307:Bibcode
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1530:214â217
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894:dyspnea
808:anxiety
760:phobias
604:in the
503:loop.
497:anxiety
491:and/or
481:choking
457:vertigo
425:dyspnea
362:puberty
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449:nausea
386:nausea
318:, and
280:DSM-IV
128:Causes
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1089:DSM-5
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