206:
witness" and that the parents who brought the case were "misled by physicians who are guilty, in my view, of gross medical misjudgment." In another case, the judge noted of
Krigsman's qualification for identifying a new disease like "autistic enterocolitis" which is "unrecognized by other authorities in the field, were, even when inflated, sadly lacking" and that his testimony about the existence of "autistic enterocolitis" was "speculative and unsupported by the weight of the evidence."
205:
provided by
Krigsman. They noted concerns regarding a title he said he held at New York University Medical School which may not have matched his duties as well as possible misrepresentations of publications he has published. In one case, the judge noted that he thinks Krigsman was not a "credible
149:
and the MMR vaccine. In 2003, Krigsman, who was at Lenox Hill, reported similar findings as those of
Wakefield, saying he found the intestines of 40 autistic children showed signs of inflammation, thus lending support to Wakefield's ideas that MMR was related to autism and also to gastrointestinal
167:
However, the concept of "autistic enterocolitis" has not been accepted in the medical community due to lack of rigorous studies confirming the condition, as many studies purportedly showing this diagnosis have been marred by numerous methodological faults. Even a position statement by a panel of
47:. The original study that tied the MMR vaccine to autism and GI complaints conducted by one of Krigsman's associates has been found to be fraudulent, and the diagnosis of "autistic enterocolitis" has not been accepted by the medical community.
115:
about research he had done on 43 patients, and later refused to provide medical charts as requested by a committee set up by the hospital to investigate the situation, before resigning from the hospital in 2004.
91:
in general pediatrics and in pediatric gastroenterology, though no longer practices general pediatrics. In April 2010, Krigsman left
Thoughtful House to open a private practice in Austin and New York.
107:
Office for Human
Research Protections later reviewed the situation, noting reports from the hospital that Krigsman applied for permission to conduct research but was not approved by the institution's
199:" rendering decisions about these cases have questioned his credibility due to previous regulatory sanctions by the Texas Medical Board and Lenox Hill Hospital, as well as concerns regarding the
619:
175:
Andrew
Wakefield, who later joined and worked with Krigsman at Thoughtful House, was found to have falsified the 1998 Lancet study, which was described as "an elaborate fraud."
172:
that included
Krigsman concluded that the clinical significance of the findings of inflammation in the intestines is unknown as it is also found in children without autism.
979:
737:
164:
published the memoir of a mother with two autistic children, which heavily featured Dr. Krigsman and detailed his treatment protocol from the patient perspective.
383:
969:
67:
at
Brooklyn in 1989 and later completed his pediatric residency at SUNY Brooklyn's Kings County Medical Center. After completing pediatric gastroenterology
127:
in Texas, for failing to report previous regulatory sanctions by the
Florida medical board, and for the disciplinary action by the Lenox Hill Hospital.
620:"Clinical Presentation and Histologic Findings at Ileocolonoscopy in Children with Autistic Spectrum Disorder and Chronic Gastrointestinal Symptoms"
766:
104:
639:
954:
674:
111:, which was concerned about risk to patients from unwarranted procedures. The report also noted Krigsman nevertheless testified before a
571:
933:
596:
959:
64:
99:
In 2004, Krigsman left Lenox Hill under "questionable circumstances," after his hospital privileges were restricted from conducting
468:
984:
964:
103:
due to allegations that he was performing medically unwarranted endoscopies on autistic children for research purposes. The
306:"Identification of Unique Gene Expression Profile in Children with Regressive Autism Spectrum Disorder (ASD) and Ileocolitis"
889:
828:
733:
442:
188:
79:
from 2000 through 2004 in the same position. He subsequently left to work as director of the gastroenterology clinic at
540:
974:
376:
108:
72:
56:
40:
505:"Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children"
28:
949:
263:"Decreased Serum Hepatocyte Growth Factor (HGF) in Autistic Children with Severe Gastrointestinal Disease"
44:
123:
for multiple violations, including representing he was available to see patients prior to obtaining his
112:
68:
759:
80:
934:'Wake Forest Researcher Warns Against Making Connection Between Presence of Measles Virus and Autism'
317:
156:
120:
88:
76:
412:
150:
disease. This information was not formally published until seven years later in 2010, in the non-
881:
820:
715:
532:
60:
39:. He specializes in the evaluation and treatment of gastrointestinal pathology in children with
24:
873:
812:
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670:
563:
524:
345:
292:
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690:
MacDonald TT, Domizio P (2007). "Autistic enterocolitis; is it a histopathological entity?".
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335:
325:
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136:
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195:") by parents seeking compensation for damages purportedly caused by vaccination. The "
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244:
217:
196:
184:
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559:
520:
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Walker, S. J.; Fortunato, J.; Gonzalez, L. G.; Krigsman, A. (2013). Hu, Wenhui (ed.).
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703:
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161:
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824:
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20:
536:
330:
851:
792:
32:
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218:"Low serum myeloperoxidase in autistic children with gastrointestinal disease"
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504:
145:, where he purported an association between autistic regression, intestinal
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877:
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349:
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36:
382:. Office of Special Masters, United States Court of Special Claims.
852:"Wakefield's article linking MMR vaccine and autism was fraudulent"
187:
in a number of test claims to the Office of
Special Masters of the
71:
in 1995, he joined the Department of Pediatric Gastroenterology of
448:. Office of Special Masters, United States Court of Special Claims
856:
261:
Russo, A. J.; Krigsman, A.; Jepson, B.; Wakefield, A. (2009).
216:
Russo, A. J.; Krigsman, A.; Jepson, B.; Wakefield, A. (2009).
936:, Wake Forest University Baptist Medical center, January 2006
618:
Krigsman, A; Boris M; Goldblatt A; Stott C (1 January 2010).
474:. Office for Human Research Protections, DHHS. Archived from
139:
in 1998 after the publication of his now-retracted study in
408:
65:
State University of New York Downstate College of Medicine
75:
in New York as Director through 2000, and later joined
43:, and has written in support of the diagnosis he calls
914:'Arthur Krigsman in Close Vote at Texas Medical Board'
662:
436:
434:
432:
430:
409:"Pediatric Gastroenterology of New York and Texas"
31:research in which he attempted to prove that the
793:"How the case against the MMR vaccine was fixed"
135:The term "autistic enterocolitis" was coined by
734:"Autism Speaks Hosts Gastroenterology Workshop"
370:
368:
366:
8:
926:, US court of federal claims, June 2007, at
503:; Murch S; Anthony A; et al. (1998).
222:Clinical and Experimental Gastroenterology
980:SUNY Downstate College of Medicine alumni
339:
329:
286:
243:
233:
850:Godlee F, Smith J, Marcovitch H (2011).
362:
105:Department of Health and Human Services
543:from the original on 27 September 2007
121:Texas State Board of Medical Examiners
892:from the original on 11 November 2013
772:from the original on 29 December 2010
740:from the original on 29 December 2010
7:
831:from the original on 12 January 2011
599:from the original on 20 January 2011
415:from the original on 28 January 2011
970:American anti-vaccination activists
587:Begley, Sharon (21 February 2009).
119:In 2005, Krigsman was fined by the
14:
924:'Arthur Krigsman cross-examined'
704:10.1111/j.1365-2559.2007.02606.x
389:from the original on 12 May 2009
469:"Letter to Lenox Hill Hospital"
83:, where he was colleagues with
1:
560:10.1016/S0140-6736(10)60175-4
521:10.1016/S0140-6736(97)11096-0
183:Krigsman has testified as an
131:Controversial autism research
35:caused diseases, especially
955:American gastroenterologists
760:"Autism Speaks GI Statement"
331:10.1371/journal.pone.0058058
189:U.S. Court of Federal Claims
1001:
109:Institutional Review Board
73:Beth Israel Medical Center
960:American health activists
661:Noonan, Jennifer (2016).
41:autism spectrum disorders
916:, November 21, 2005, at
191:(commonly known as the "
179:Expert witness testimony
168:physicians sponsored by
57:Johns Hopkins University
985:MMR vaccine and autism
965:American pediatricians
665:No Map to This Country
59:, Krigsman earned his
45:autistic enterocolitis
554:(Retracted, see
467:McNeilly, Patrick J.
210:Selected publications
113:Congressional hearing
669:. Da Capo Lifelong.
589:"Anatomy of a Scare"
441:Hastings, George L.
51:Education and career
322:2013PLoSO...858058W
89:board certification
77:Lenox Hill Hospital
27:best known for his
975:Autism researchers
642:on 9 February 2011
375:Vowell, Denise K.
267:Biomarker Insights
87:. Krigsman holds
61:Doctor of Medicine
25:gastroenterologist
870:10.1136/bmj.c7452
809:10.1136/bmj.c5347
765:. Autism Speaks.
736:. Autism Speaks.
676:978-0-7382-1904-2
636:10.4137/AUI.S3252
279:10.4137/BMI.S3656
235:10.2147/CEG.S6051
160:. In April 2016,
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638:. Archived from
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573:Retraction Watch
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515:(9103): 637–41.
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202:curriculum vitae
162:Da Capo Lifelong
154:indexed journal
137:Andrew Wakefield
85:Andrew Wakefield
81:Thoughtful House
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692:Histopathology
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481:on 29 May 2010
459:
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377:"Snyder v HHS"
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185:expert witness
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640:the original
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21:pediatrician
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547:5 September
501:Wakefield A
273:: 181–190.
101:endoscopies
33:MMR vaccine
944:Categories
928:Brian Deer
918:Brian Deer
896:4 February
835:4 February
776:4 February
744:4 February
646:4 February
603:4 February
485:4 February
452:4 February
419:4 February
393:4 February
358:References
142:The Lancet
69:fellowship
864:: c7452.
803:: c5347.
228:: 85–94.
890:Archived
886:43640126
878:21209060
829:Archived
825:46683674
817:21209059
767:Archived
738:Archived
720:22342418
712:17257133
630:: 1–11.
597:Archived
593:Newsweek
568:20137807
541:Archived
413:Archived
384:Archived
350:23520485
310:PLOS ONE
297:20029653
254:21694831
529:9500320
341:3592909
318:Bibcode
288:2796865
245:3108639
152:MEDLINE
63:at the
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95:Ethics
37:autism
882:S2CID
821:S2CID
770:(PDF)
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716:S2CID
533:S2CID
479:(PDF)
472:(PDF)
446:(PDF)
387:(PDF)
380:(PDF)
19:is a
930:.com
920:.com
898:2011
874:PMID
837:2011
813:PMID
778:2011
746:2011
708:PMID
671:ISBN
648:2011
605:2011
564:PMID
549:2007
525:PMID
487:2011
454:2011
421:2011
395:2011
346:PMID
293:PMID
250:PMID
23:and
866:doi
862:342
857:BMJ
805:doi
801:342
797:BMJ
700:doi
632:doi
556:doi
517:doi
513:351
336:PMC
326:doi
283:PMC
275:doi
240:PMC
230:doi
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