Knowledge (XXG)

Ashani Weeraratna

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Hsin-Yao; Yin, Xiangfan; Wood, William H.; Lehrmann, Elin; Becker, Kevin G.; Flaherty, Keith T.; Frederick, Dennie T.; Wargo, Jennifer A.; Cooper, Zachary A.; Tetzlaff, Michael T.; Hudgens, Courtney; Aird, Katherine M.; Zhang, Rugang; Xu, Xiaowei; Liu, Qin; Bartlett, Edmund; Karakousis, Giorgos; Eroglu, Zeynep; Lo, Roger S.; Chan, Matthew; Menzies, Alexander M.; Long, Georgina V.; Johnson, Douglas B.; Sosman, Jeffrey; Schilling, Bastian; Schadendorf, Dirk; Speicher, David W.; Bosenberg, Marcus; Ribas, Antoni; Weeraratna, Ashani T. (April 4, 2016).
916: 221:, then known as the Johns Hopkins Oncology Center. From there, she went on to become a Staff Scientist in the laboratory of Jeff Trent, then Scientific Director of the National Human Genome Research Institute, at the National Institutes of Health. It was here that she followed up on the discovery by Dr Trent, and Dr. Michael Bittner, of the non-canonical Wnt signaling molecule, Wnt5A in melanoma. She spent the next decade or so of her career trying to understand the role of Wnt5A in melanoma metastasis. 484:
Kaur, Amanpreet; Webster, Marie R.; Marchbank, Katie; Behera, Reeti; Ndoye, Abibatou; Kugel, Curtis H.; Dang, Vanessa M.; Appleton, Jessica; O’Connell, Michael P.; Cheng, Phil; Valiga, Alexander A.; Morissette, Rachel; McDonnell, Nazli B.; Ferrucci, Luigi; Kossenkov, Andrew V.; Meeth, Katrina; Tang,
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remarked that "Dr. Weeraratna has demonstrated outstanding scientific initiative and is a great ambassador for our Institute...she is changing the way we understand melanoma, as she and her team seek ways to prevent and treat this dangerous disease. Under her leadership, we look forward to continued
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innovation and growth during these exciting times of research expansion at Wistar." In 2018, Dr. Weeraratna is head of the Weeraratna Lab at the Wistar Institute. The lab researches molecular mechanisms related to melanoma metastasis, especially the
333:, instead highlighting the scientific achievements and economic growth attributed to immigrants in the United States. She urged others to exercise their right to vote, stating that she was only recently able to do so because she is an immigrant. 250:. In 2015, her research encompassed the effects of aging on skin and the corresponding changes in tumor growth. She was named the Ira Brind associate professor, in 2016. In receiving the professorship, Wistar Institute president and CEO, 262:
In 2018, Weeraratna became a full professor and co-program leader of the Immunology, Microenvironment, and Metastasis Program at the Wistar Institute. Until 2018, she was the program director of the Cancer Biology doctorate program at
173:. At the Wistar Institute, Weeraratna was a full professor and co-program leader of the Immunology, Microenvironment, and Metastasis Program at the Wistar Institute and the program director of the cancer biology program at the 848: 1066: 360: 238:. Weeraratna joined the Wistar Institute in 2011, first as an assistant professor and then as an associate professor and program leader of the Tumor Microenvironment and Metastasis Program at 874: 166:. Weeraratna is a member of the National Cancer Advisory Board, which advises and assists the director of the National Cancer Institute on the activities of the national cancer program. 217:
was her doctoral advisor. From 1998 to 2000, Weeraratna completed post-graduate training and was a postdoctoral fellow in experimental therapeutics and pharmacology at the Johns Hopkins
1021: 624: 996: 1006: 158:(born 1970 or 1971) is a Sri Lanka-born American cancer researcher whose findings are contributing to the scientific understanding of melanoma tumors. She is a 1061: 956: 941: 279: 163: 375:
Weeraratna, Ashani T.; Arnold, Julia T.; George, Dan J.; Demarzo, Angelo; Isaacs, John T. (2000). "Rational basis for Trk inhibition therapy for prostate cancer".
259:. Weeraratna also investigates how changes to tumor microenvironment, especially aging, can change melanoma growth and the development of therapeutic resistance. 991: 330: 282:(JHSPH). In this role, she will continue her melanoma research and expand the aging and cancer programs at JHSPH. Weeraratna holds a joint appointment in the 1011: 206: 278:
of cancer biology. She will serve as the first female E.V. McCollum Professor and Chair of the department of biochemistry and molecular biology at the
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appointed Weeraratna as one of seven clinicians and researchers to the National Cancer Advisory Board, which advises the director of the
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Weeraratna, Ashani T.; Jiang, Yuan; Hostetter, Galen; Rosenblatt, Kevin; Duray, Paul; Bittner, Michael; Trent, Jeffrey M. (2002).
1031: 559: 283: 388: 1056: 849:"The Wistar Institute Names Ashani Weeraratna, PhD, the Ira Brind Associate Professor for Outstanding Scientific Leadership" 162:
of cancer biology and the E.V. McCollum Professor and Chair of the department of biochemistry and molecular biology at the
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in 1997, during which time she met the Hand. She earned a doctorate in Molecular and Cellular Oncology from the
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Weeraratna, Ashani T. (2005). "A Wnt-er Wonderland—The complexity of Wnt signaling in melanoma".
400: 748: 738: 686: 524: 464: 435: 392: 514: 506: 456: 425: 384: 239: 197:. She earned a bachelor's degree in 1991. Weeraratna obtained a Master's in Philosophy from 170: 135: 915: 907: 596:"Leach Leads Hundreds in Protest Demanding Trump Keep Families Together - Senator Leach" 502: 325:. She revealed the difficulties she faced while emigrating without family to pursue the 911: 519: 486: 326: 566: 487:"sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance" 430: 413: 925: 657:"Expert in cancer and aging joins Johns Hopkins as Bloomberg Distinguished Professor" 251: 476: 414:"Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma" 404: 322: 781: 782:"Promotion of tumor invasion and pseudosenescence by the aging microenvironment" 189:. From the age of 15, she wanted to become a cancer researcher. In 1988, due to 460: 68: 982:
George Washington University School of Medicine & Health Sciences alumni
752: 690: 298: 243: 190: 528: 468: 439: 396: 91: 510: 193:, Weeraratna left Southern Africa at the age of 17 to study biology at 186: 389:
10.1002/1097-0045(20001001)45:2<140::AID-PROS8>3.0.CO;2-#
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Loss of uteroglobin expression in metastatic human prostate cancer
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In 2007, Weeraratna worked in the Laboratory of Immunology at the
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Loss of Uteroglobin Expression in Metastatic Human Prostate Cancer
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Loss of Uteroglobin Expression in Metastatic Human Prostate Cancer
737:. Korenberg, Michael J. Totowa, N.J.: Humana Press. 2007. 735:
Microarray data analysis : methods and applications
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Johns Hopkins Bloomberg School of Public Health faculty
290:. In 2020, Weeraratna will serve as president of the 131: 123: 115: 110: 100: 85: 67: 62: 50: 42: 30: 23: 280:Johns Hopkins Bloomberg School of Public Health 185:Weeraratna was born in Sri Lanka and raised in 164:Johns Hopkins Bloomberg School of Public Health 305:on activities of the national cancer program. 1022:Columbian College of Arts and Sciences alumni 331:Trump administration family separation policy 8: 207:George Washington University Medical Center 914: 169:She was head of the Weeraratna Lab at the 20: 997:Sri Lankan emigrants to the United States 875:"Cancer Biology Graduate Program Faculty" 518: 429: 288:Sidney Kimmel Comprehensive Cancer Center 219:Sidney Kimmel Comprehensive Cancer Center 38:1970 or 1971 (age 52–53) 801:Ashani Weeraratna on Aging and Melanoma 705:"Ashani Weeraratna - Faculty Biosketch" 542: 364:, Johns Hopkins University Press, 2021. 242:. In 2014, she was the recipient of an 1062:Lesotho emigrants to the United States 957:21st-century American women scientists 942:20th-century American women scientists 823:"People on the Move: Wistar Institute" 758: 203:Columbian College of Arts and Sciences 1007:St. Mary's College of Maryland alumni 804:, OncLive Insights, December 14, 2015 16:Sri Lankan-American cancer researcher 7: 992:National Institutes of Health people 650: 648: 646: 619: 617: 590: 588: 586: 584: 554: 552: 550: 548: 546: 313:In June 2018, Weeraratna spoke at a 329:. Weeraratna spoke out against the 209:. Her 1998 dissertation was titled 1012:University of the Sciences faculty 681:Weeraratna, Ashani Tanuja (1998). 14: 276:Bloomberg Distinguished Professor 160:Bloomberg Distinguished Professor 987:Johns Hopkins University fellows 952:21st-century American scientists 937:20th-century American scientists 284:Johns Hopkins School of Medicine 967:American civil rights activists 286:department of oncology and the 1072:Biden administration personnel 655:Pearce, Katie (July 2, 2019). 195:St. Mary's College of Maryland 74:St. Mary's College of Maryland 1: 962:21st-century Sri Lankan women 947:20th-century Sri Lankan women 449:Cancer and Metastasis Reviews 431:10.1016/S1535-6108(02)00045-4 297:In September 2021, President 292:Society of Melanoma Research 199:George Washington University 79:George Washington University 1002:Sri Lankan women scientists 837:– via Newspapers.com. 236:National Institute on Aging 1088: 1052:Sri Lankan women educators 879:University of the Sciences 560:"Ashani Weeraratna, Ph.D." 265:University of the Sciences 175:University of the Sciences 140:University of the Sciences 972:American women biologists 827:The Philadelphia Inquirer 461:10.1007/s10555-005-1574-z 303:National Cancer Institute 248:National Cancer Institute 149: 58: 1042:American women educators 910:publications indexed by 661:Johns Hopkins University 348:Google Scholar citations 315:Families Belong Together 272:Johns Hopkins University 181:Early life and education 156:Ashani Tanuja Weeraratna 144:Johns Hopkins University 35:Ashani Tanuja Weeraratna 1032:Lesotho women educators 765:: CS1 maint: others ( 1057:Immigrants to Lesotho 361:Is Cancer Inevitable? 257:Wnt signaling pathway 1047:Sri Lankan educators 780:Ashani, Weeraratna. 631:. September 15, 2021 855:. September 9, 2016 511:10.1038/nature17392 503:2016Natur.532..250K 127:Melanoma metastasis 63:Academic background 1037:American educators 977:Cancer researchers 829:. October 10, 2016 270:Weeraratna joined 1027:Lesotho educators 908:Ashani Weeraratna 709:www.med.upenn.edu 497:(7598): 250–254. 369:Selected Articles 153: 152: 25:Ashani Weeraratna 1079: 918: 895: 894: 892: 890: 885:on March 9, 2021 881:. Archived from 871: 865: 864: 862: 860: 845: 839: 838: 836: 834: 819: 813: 812: 811: 809: 796: 790: 789: 777: 771: 770: 764: 756: 731: 725: 724: 722: 720: 711:. Archived from 701: 695: 694: 678: 672: 671: 669: 667: 652: 641: 640: 638: 636: 621: 612: 611: 609: 607: 592: 579: 578: 576: 574: 569:on July 10, 2018 565:. 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Index

Alma mater
St. Mary's College of Maryland
George Washington University
Thesis
Loss of Uteroglobin Expression in Metastatic Human Prostate Cancer
Steven Patierno
Wistar Institute
University of the Sciences
Johns Hopkins University
Bloomberg Distinguished Professor
Johns Hopkins Bloomberg School of Public Health
Wistar Institute
University of the Sciences
Lesotho
apartheid
St. Mary's College of Maryland
George Washington University
Columbian College of Arts and Sciences
George Washington University Medical Center
Steven Patierno
Sidney Kimmel Comprehensive Cancer Center
National Institute on Aging
Wistar Institute
R01 grant
National Cancer Institute
Dario Altieri
Wnt signaling pathway
University of the Sciences
Johns Hopkins University
Bloomberg Distinguished Professor

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