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Burkholderia pseudomallei

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can go through transformation. The bacteria is able to uptake a free plasmid using electroporation and the plasmid material will integrate into the host DNA when they are electrocompetent. An example is given by an experiment performed by Mack K. and Titball R. W., which showed that a Burkholderia
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is very variable and a single strain may display multiple colony types, so inexperienced laboratory staff may mistakenly believe the growth is not pure. The organism grows more slowly than other bacteria that may be present in clinical specimens, and in specimens from nonsterile sites, is easily
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survived in distilled water for 16 years, demonstrating that it is capable of living in water if a specific environment is provided. It is resistant to a variety of harsh conditions including nutrient deficiency, extreme temperature or pH. It infects humans, causing the disease
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Nandi T, Ong C, Singh AP, Boddey J, Atkins T, Sarkar-Tyson M, Essex-Lopresti AE, Chua HH, Pearson T, Kreisberg JF, Nilsson C, Ariyaratne P, Ronning C, Losada L, Ruan Y, Sung WK, Woods D, Titball RW, Beacham I, Peak I, Keim P, Nierman WC, Tan P (2010). Guttman DS (ed.).
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regions worldwide, particularly in Thailand and northern Australia. It was reported in 2008 that there had been an expansion of the affected regions due to significant natural disasters, and it could be found in Southern China, Hong Kong, and countries in the Americas.
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Baker, Sarah M.; Settles, Erik W.; Davitt, Christopher; Gellings, Patrick; Kikendall, Nicole; Hoffmann, Joseph; Wang, Yihui; Bitoun, Jacob; Lodrigue, Kasi-Russell; Sahl, Jason W.; Keim, Paul; Roy, Chad; McLachlan, James; Morici, Lisa A. (29 January 2021).
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and is helpful in identification. Unfortunately, the majority of strains in Sarawak, Borneo, are susceptible to aminoglycosides and macrolides, which means the conventional recommendations for isolation and identification do not apply there.
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Rodríguez, José Y.; Huertas, Mónica G.; Rodríguez, Gerson J.; Vargas-Otalora, Sandra; Benıtez-Peñuela, Miguel A.; Esquea, Kelin; Rios, Rafael; Mendoza, Laura R.; Diaz, Lorena; Reyes, Jinnethe; Álvarez-Moreno, Carlos A. (2020-11-04).
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or Whitmore's disease. It is spread though direct contact with water or soil that holds the bacteria. There have been few cases of transmission of the bacteria perinatally. Its mortality is 20 to 50% even with treatment.
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is an opportunistic pathogen. An environmental organism, it has no requirement to pass through an animal host to replicate. From the point of view of the bacterium, human infection is a developmental "dead end".
973:. It may have the ability to cause disease in humans because of DNA it has acquired from other microorganisms. Its mutation rate is also high, and the organism continues to evolve even after infecting a host. 455:
can be difficult, especially in Western countries where it is rarely seen. The large, wrinkled colonies look like environmental contaminants, so are often discarded as being of no clinical significance.
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is one of the first Proteobacteria to be identified as containing an active type VI secretion system. It is also the only organism identified that contains up to six different type VI secretion systems.
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in cultures may not actually trigger alarms in physicians unfamiliar with the disease. Routine biochemical methods for identification of bacteria vary widely in their identification of this organism: the
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rod with a characteristic "safety pin" appearance (bipolar staining). On sensitivity testing, the organism appears highly resistant (it is innately resistant to many antibiotics including
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Limmathurotsakul, Direk; Golding, Nick; Dance, David A. B.; Messina, Jane P.; Pigott, David M.; Moyes, Catherine L.; Rolim, Dionne B.; Bertherat, Eric; Day, Nicholas P. J. (2016-01-11).
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Ruppitsch W, Stöger A, Indra A, et al. (March 2007). "Suitability of partial 16S ribosomal RNA gene sequence analysis for the identification of dangerous bacterial pathogens".
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in clinical samples is of an intracellular, bipolar-staining, Gram-negative rod, but this is of little value in identifying the organism from clinical samples. Some suggest the
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isolates are intrinsically resistant to all aminoglycosides (via an efflux pump mechanism), but sensitive to co-amoxiclav: this pattern of resistance almost never occurs in
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agent. It infects other animals, most commonly livestock such as goats, pigs, and sheep, less frequently. It is also capable of infecting plants in a laboratory setting.
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Trunck LA; Propst, KL; Wuthiekanun, V; Tuanyok, A; Beckstrom-Sternberg, SM; Beckstrom-Sternberg, JS; Peacock, SJ; Keim, P; et al. (2009). Picardeau, Mathieu (ed.).
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tests should be used in preference. The actions of co-trimoxazole and doxycycline are antagonistic, which suggests these two drugs ought not to be used together.
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Pumpuang, Apinya; Chantratita, Narisara; Wikraiphat, Chanthiwa; Saiprom, Natnaree; Day, Nicholas P.J.; Peacock, Sharon J.; Wuthiekanun, Vanaporn (October 2011).
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White NJ, Dance DA, Chaowagul W, Wattanagoon Y, Wuthiekanun V, Pitakwatchara N (September 1989). "Halving of mortality of severe melioidosis by ceftazidime".
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Brundage WG, Thuss CJ, Walden DC (March 1968). "Four fatal cases of melioidosis in U. S. soldiers in Vietnam. Bacteriologic and pathologic characteristics".
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medium) may be used for selective isolation. Cultures typically become positive in 24 to 48 hours (this rapid growth rate differentiates the organism from
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1026b does not play a role in quorum sensing, virulence factor production, or extrusion of aminoglycosides, but is a broad-spectrum drug efflux system"
5779: 5818: 3578:"The Type VI secretion system spike protein VgrG5 mediates membrane fusion during intercellular spread by pseudomallei group Burkholderia species" 4123: 5336: 3908:"Glyphosate resistance as a novel select-agent-compliant, non-antibiotic-selectable marker in chromosomal mutagenesis of the essential genes 3875: 1287: 4731: 419:, which is in contrast, exquisitely sensitive to many antibiotics. For environmental specimens only, differentiation from the nonpathogenic 4986: 1038: 983:, and to spread from cell to cell, causing cell fusion and the formation of multinucleated giant cells. It possesses a uniquely fusogenic 399:, which typically takes a minimum of 72 hours to grow). Colonies are wrinkled, have a metallic appearance, and possess an earthy odor. On 5900: 4412: 987:
that is required for cell-cell spread and virulence in mammalian hosts. The bacterium also expresses a toxin called lethal factor 1.
4540: 4183: 3799:"Burkholderia pseudomallei OMVs derived from infection mimicking conditions elicit similar protection to a live-attenuated vaccine" 542:
hybridisation has also been described, but has not been clinically validated, and it is not commercially available. In Thailand, a
4105: 4976: 4981: 4522: 5644: 3981:Δasd mutant exhibits attenuated intracellular infectivity and imparts protection against acute inhalation melioidosis in mice" 4554: 5823: 484:
Even when the isolate is recognized to be significant, commonly used identification systems may misidentify the organism as
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to trimethoprim-sulfamethoxazole by standard disk diffusion method and by minimal inhibitory concentration determination".
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Lumbiganon P, Tattawasatra U, Chetchotisakd P, et al. (2000). "Comparison between the antimicrobial susceptibility of
4370: 2020:"Contribution of the BacT/ALERT MB Mycobacteria Bottle to bloodstream infection surveillance in Thailand: added yield for 923:
for the treatment of acute melioidosis. Disc diffusion tests are unreliable when looking for co-trimoxazole resistance in
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in 99% of cases, as does the automated Vitek 1 system, but the automated Vitek 2 system only identifies 19% of isolates.
5540: 4864: 4300: 68: 5805: 5201: 5195: 4811: 358:. The role of the toxins identified in the process of melioidosis symptom development has not been fully elucidated. 5280: 1245: 421: 5849: 4258: 4133: 5895: 5001: 4805: 4735: 4516: 546:
assay is widely used, while a rapid immunofluorescence technique is also available in a small number of centres.
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Strains which cause disease in humans differ from those causing disease in other animals, by possessing certain
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induces cell fusion and actin-associated membrane protrusion: a possible mechanism for cell-to-cell spreading"
326:, optimal proliferation temperature is reported around 40 Â°C in neutral or slightly acidic environments ( 5680: 5560: 5520: 5462: 5181: 4948: 4384: 4342: 4090: 283:
Although it is mainly a soil-dwelling bacteria, a study performed by Apinya Pumpuang and others showed that
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The pattern of resistance to antimicrobials is distinctive, and helps to differentiate the organism from
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medium). For heavily contaminated samples, such as feces, a modified version of Ashdown's that includes
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pseudomallei 4845 was capable of transformation by electroporation, utilizing the incQ plasmid pKT230.
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overgrown. Nonsterile specimens should, therefore, be cultured in selective media (e.g., Ashdown's or
5859: 5766: 5674: 5634: 5587: 5469: 5120: 5078: 5058: 5015: 4871: 4670: 4350: 3931: 3654: 2866: 492: 481:) by bioMĂ©rieux has been shown to have superior yields compared to conventional blood culture media. 382: 1515:"Toxin production by Burkholderia pseudomallei strains and correlation with severity of melioidosis" 5652: 5597: 5266: 5142: 5087: 5035: 4954: 4897: 4850: 4785: 4633: 4625: 4619: 4336: 4322: 4191: 1034:
As of 2023 no vaccine had been licensed, although many had been evaluated in pre-clinical studies.
836: 543: 395: 386: 276:, amongst other pathogens, has been found in monkeys imported into the United States from Asia for 1966: 5640: 5551: 5052: 5041: 4962: 4906: 4694: 4392: 4378: 4308: 4285: 3881: 3505: 3001: 2493: 2344: 2100: 1101:
Yabuuchi, E; Kosako, Y; Oyaizu, H; Yano, I; Hotta, H; Hashimoto, Y; Ezaki, T; Arakawa, M (1992).
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in the laboratory, but the concentrations used are much higher than those achievable in humans.
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Hemarajata, Peera; Baghdadi, Jonathan D.; Hoffman, Risa; Humphries, Romney M. (December 2016).
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from Sarawak, Malaysian Borneo are predominantly susceptible to aminoglycosides and macrolides"
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measures 2–5 ÎŒm in length and 0.4–0.8 ÎŒm in diameter and is capable of self-propulsion using
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has been proposed. In blood culture, the BacT/ALERT MB system (normally used for culturing
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Inglis TJ, Chiang D, Lee GS, Chor-Kiang L (February 1998). "Potential misidentification of
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Kespichayawattana W, Intachote P, Utaisincharoen P, Stitaya Sirisinha S (2004). "Virulent
1050: 1003: 970: 908: 855:. The microorganism can also be destroyed by heating to above 74 Â°C for 10 min or by 193: 110: 5836: 2511:
Wattiau P, Van Hessche M, Neubauer H, Zachariah R, Wernery U, Imberechts H (March 2007).
2364:"A comparison of routine bench and molecular diagnostic methods in the identification of 2175: 3935: 3658: 2870: 5666: 5316: 5310: 5173: 5069: 5026: 4921: 4442: 4209: 4179: 4109: 4005: 3976: 3952: 3907: 3833: 3798: 3773: 3744: 3675: 3634: 3610: 3577: 3447: 3416: 3392: 3361: 3334: 3303: 3235: 3206: 3182: 3151: 2953: 2895: 2854: 2830: 2801: 2720: 2687: 2639: 2614: 2541: 2512: 2445: 2416: 2392: 2363: 2238: 2209: 2048: 2019: 1995: 1864: 1835: 1811: 1782: 1758: 1733: 1732:
Sheridan EA, Ramsay AR, Short JM, Stepniewska K, Wuthiekanun V, Simpson AJ (May 2007).
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Wuthiekanun V, Wongsuwan G, Pangmee S, Teerawattanasook N, Day NP, Peacock SJ (2010).
2777: 2744: 2151: 2122: 1261: 1189:"Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis" 5889: 5662: 5578: 5405: 5360: 5101: 5093: 4936: 4703: 4614: 4274: 4240: 4215: 4200: 3885: 2517:
and related bacteria by multiple-locus sequence typing-derived PCR and real-time PCR"
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is able to invade cells (it is an intracellular pathogen). It is able to polymerise
932: 404: 400: 310:. The bacteria can grow in a number of artificial nutrient environments, especially 248: 3544: 3509: 3005: 2497: 2348: 2104: 502:. Again, because the disease is rarely seen in Western countries, identification of 5658: 5432: 4911: 4639: 4579: 4526: 4511: 4456: 2630: 1288:"US public not warned that monkeys imported from Cambodia carried deadly pathogens" 478: 445: 297: 130: 5758: 3720: 3279: 1386: 1313: 3437: 3415:
Price EP, Hornstra HM, Limmathurotsakul D, et al. (2010). Guttman DS (ed.).
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I. Morphology, cultivation, viability, and isolation from contaminated specimens"
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Chaiyaroj SC, Kotrnon K, Koonpaew S, Anantagool N, White NJ, Sirisinha S (1999).
1329: 1246:"The global distribution of Burkholderia pseudomallei and melioidosis: an update" 330:
6.8–7.0). The majority of strains are capable of oxidation, not fermentation, of
5738: 5232: 5187: 5138: 4842: 4594: 2688:"Burkholderia pseudomallei: Challenges for the Clinical Microbiology Laboratory" 2564:
Hagen RM, Frickmann H, Elschner M, et al. (2011). "Rapid identification of
1046: 999: 912: 896: 890: 877: 868: 856: 474: 470: 466: 289: 3815: 2821: 2591: 17: 4606: 3867: 3700:"In vivo expression technology identifies a type VI secretion system locus in 2415:
Podin Y, Sarovich DS, Price EP, Kaestli M, Mayo M, Hii K, et al. (2013).
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is never isolated from clinical specimens). The laboratory identification of
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Toesca, Isabelle J.; French, Christopher T.; Miller, Jeff F. (2014-04-01).
3562: 3501: 3456: 3401: 3343: 3287: 3191: 3152:"Molecular basis of rare aminoglycoside susceptibility and pathogenesis of 3136: 3081: 3036: 2962: 2920: 2904: 2839: 2786: 2729: 2648: 2599: 2550: 2489: 2454: 2401: 2340: 2300: 2247: 2191: 2160: 2057: 2004: 1951: 1873: 1820: 1767: 1670:
Walsh AL, Wuthiekanun V (1996). "The laboratory diagnosis of melioidosis".
1653: 1604: 1499: 1412: 1355: 1269: 1230: 4061: 2997: 2936: 2096: 1986: 1718: 1683: 1540: 1140: 5723: 4856: 3996: 3943: 3859:
Vaccines for Neglected Pathogens: Strategies, Achievements and Challenges
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how important is this combination in maintenance therapy of melioidosis?"
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hybridization (FISH) from culture and paraffin-embedded tissue samples".
2532: 2436: 2383: 2282: 2229: 2039: 1912: 1749: 1620:"Differences in genomic macrorestriction patterns of arabinose-positive ( 998:
is intrinsically resistant to many antimicrobial agents by virtue of its
943: 408: 351: 322: 315: 307: 80: 3492: 3471: 2261:
Moore RA, DeShazer D, Reckseidler S, Weissman A, Woods DE (March 1999).
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identification using the API 20NE system and a latex agglutination test"
2123:"Comparison of automated and nonautomated systems for identification of 1802: 448:
is useful for this purpose, but this has been shown not to be the case.
280:, posing a risk that the pathogen could be introduced into the country. 5784: 5447: 5393: 4747: 4712: 1926:
Roesnita B; Tay ST; Puthucheary SD; Sam IC. (2012). "Diagnostic use of
1783:"Biological relevance of colony morphology and phenotypic switching by 1734:"Evaluation of the Wayson stain for the rapid diagnosis of melioidosis" 1314:"Survival of Burkholderia pseudomallei in distilled water for 16 years" 840: 343: 335: 311: 264: 3127: 2208:
Amornchai P, Chierakul W, Wuthiekanun V, et al. (November 2007).
43: 4225: 4106:"Getting a Grip on the Great Mimicker: Secrets of a Stealth Organism" 2921:"Case Report: Gestational Melioidosis through Perinatal Transmission" 1887:
Ashdown LR (1979). "An improved screening technique for isolation of
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Currie, Bart J.; Dance, David A.B.; Cheng, Allen C. (December 2008).
1054: 852: 824: 347: 256: 5700: 3523:
Kespichayawattana W, Rattanachetkul S, Wanun T, et al. (2000).
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Miller, WR; Pannell, L; Cravitz, L; Tanner, WA; Ingalls, MS (1948).
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Wuthiekanun V, Peacock SJ (June 2006). "Management of melioidosis".
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is effectively killed by the commercial disinfectants, Perasafe and
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Wiersinga WJ, van der Poll T, White NJ, Day NP, Peacock SJ (2006).
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Sim SH, Yu Y, Lin CH, et al. (October 2008). Achtman M (ed.).
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in invasion of and adherence to cultured human epithelial cells".
3052:"Trimethoprim/sulfamethoxazole resistance in clinical isolates of 2615:"Rapid immunofluorescence microscopy for diagnosis of melioidosis" 2613:
Wuthiekanun V, Desakorn V, Wongsuvan G, et al. (April 2005).
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Transactions of the Royal Society of Tropical Medicine and Hygiene
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Transactions of the Royal Society of Tropical Medicine and Hygiene
980: 946:, and this fact is helpful in the identification of the organism. 928: 331: 1781:
Chantratita N, Wuthiekanun V, Boonbumrung K, et al. (2007).
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gene removed) protects against inhalational melioidosis in mice.
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Morphological, physiological, and biochemical characteristics of
4468: 4427: 4030:"Transformation of Burkholderia pseudomallei by electroporation" 3097:"In vitro interactions between cotrimoxazole and doxycycline in 1967:"An improved selective culture medium enhances the isolation of 5771: 5704: 4152: 3633:
Cruz-Migoni A, Hautbergue GM, Artymiuk PJ, et al. (2011).
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Saraya S, Soontornpas C, Chindavijak B, Mootsikapun P (2009).
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provides insights into the evolution of accidental virulence"
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Pumpuang A, Chantratita N, Wikraiphat C, et al. (2011).
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classifies it as a "Tier 1 select agent" with potential as a
2263:"Efflux-mediated aminoglycoside and macrolide resistance in 1557:
Peacock SJ, Chieng G, Cheng AC, et al. (October 2005).
1371:"Melioidosis: Epidemiology, Pathophysiology, and Management" 2174:
Kite-Powell A, Livengood JR, Suarez J, et al. (2006).
327: 3050:
Wuthiekanun V, Cheng AC, Chierakul W, et al. (2005).
1460:"Identification of tomato plant as a novel host model for 1111:
homology group II to the new genus, with the type species
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toxin inhibits helicase activity of translation factor
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or other nonfermenting, Gram-negative bacilli such as
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showing the characteristic cornflower head morphology
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Norris MH, Kang Y, Lu D, Wilcox BA, Hoang TT (2009).
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The American Journal of Tropical Medicine and Hygiene
2855:"UV Light Inactivation of Bacterial Biothreat Agents" 2018:
Jorakate P, Higdon M, Kaewpan A, et al. (2015).
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Goodyear A, Strange L, Rholl DA, et al. (2013).
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The American Journal of Tropical Medicine and Hygiene
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gen. nov. and transfer of seven species of the genus
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Haase A, Janzen J, Barrett S, Currie B (July 1997).
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is susceptible to numerous disinfectants, including
5713: 5624: 5615: 5577: 5550: 5530: 5486: 5431: 5404: 5359: 5333: 5297: 5229: 5220: 5112: 5077: 5068: 5025: 4920: 4905: 4896: 4826: 4773: 4746: 4711: 4702: 4693: 4605: 4578: 4569: 4502: 4467: 4426: 4284: 4273: 4224: 4208: 4199: 4190: 2314: 2312: 2310: 3975:Norris MH, Propst KL, Kang Y, et al. (2011). 2802:"Perasafe, Virkon and bleach are bactericidal for 2745:"Studies on certain biological characteristics of 2362:Hodgson K, Engler C, Govan B, et al. (2009). 3472:"Melioidosis: insights into the pathogenicity of 847:, and to a lesser extent, phenolic preparations. 342:; older cultures are reported to also metabolize 2203: 2201: 2176:"Imported Melioidosis—South Florida, 2005" 292:; mortality is 20–50% even with treatment. The 1369:Cheng, Allen C.; Currie, Bart J. (April 2005). 373:and grows on a large variety of culture media ( 1930:selective media in a low prevalence setting". 958:Pathogenicity mechanisms and virulence factors 4164: 3704:that is induced upon invasion of macrophages" 2619:Clinical and Diagnostic Laboratory Immunology 2579:International Journal of Medical Microbiology 1447:. New Jersey Department of Agriculture. 2003. 1053:(DAP) in rich media and auxotrophic for DAP, 263:. It is a soil-dwelling bacterium endemic in 8: 3698:Shalom G, Shaw JG, Thomas MS (August 2007). 2806:a select agent and the cause of melioidosis" 2121:Lowe P, Engler C, Norton R (December 2002). 1665: 1663: 885:Antibiotic treatment and sensitivity testing 581:2–5 ÎŒm in length and 0.4–0.8 ÎŒm in diameter 3355: 3353: 3304:"A genomic survey of positive selection in 938:The organism is intrinsically resistant to 927:(they greatly overestimate resistance) and 5701: 5621: 5226: 5074: 4917: 4902: 4708: 4699: 4575: 4281: 4221: 4205: 4196: 4171: 4157: 4149: 1552: 1550: 42: 31: 4004: 3951: 3832: 3814: 3772: 3719: 3674: 3609: 3552: 3491: 3446: 3436: 3391: 3381: 3333: 3323: 3234: 3181: 3171: 3126: 3116: 3071: 2952: 2894: 2853:Rose, L. J.; O'Connell, H. (2009-05-01). 2829: 2776: 2719: 2638: 2540: 2444: 2391: 2290: 2237: 2150: 2047: 1994: 1863: 1810: 1757: 1643: 1594: 1567:selective agar for clinical isolation of 1530: 1489: 1479: 1458:Lee YH, Chen Y, Ouyang X, Gan YH (2010). 1402: 1345: 1220: 1130: 334:without gas formation (most importantly, 1281: 1279: 1039:Aspartate-ÎČ-semialdehyde dehydrogenase ( 1037:Vaccine candidates have been suggested. 919:), they have been proven to be inferior 560: 415:) and that again differentiates it from 4028:Mack, K.; Titball, R. W. (1996-11-01). 2321:Expert Review of Anti-infective Therapy 2116: 2114: 1093: 1002:mechanism. This mediates resistance to 2859:Applied and Environmental Microbiology 1115:(Palleroni and Holmes 1981) comb. nov" 437:has been described in the literature. 5337:Aggregatibacter actinomycetemcomitans 3366:: implications for human melioidosis" 2271:Antimicrobial Agents and Chemotherapy 7: 5860:343a0770-1e1b-43de-a99e-74e8cd0e7b77 4722:Neisseria meningitidis/meningococcus 3856:Christodoulides, Myron, ed. (2023). 440:The classic textbook description of 3421:in four cases of acute melioidosis" 3362:"The core and accessory genomes of 1286:Colley, Claire (18 December 2022). 4184:Gram-negative bacterial infections 1645:10.1111/j.1348-0421.1999.tb02449.x 1132:10.1111/j.1348-0421.1992.tb02129.x 511:20NE system accurately identifies 25: 4541:Human monocytotropic ehrlichiosis 3262:is more efficient than avirulent 1559:"Comparison of Ashdown's medium, 4757:Neisseria gonorrhoeae/gonococcus 4732:Waterhouse–Friderichsen syndrome 4108:. Wellcome Trust. Archived from 4083:genomes and related information" 3156:clinical isolates from Thailand" 2692:Journal of Clinical Microbiology 2521:Journal of Clinical Microbiology 2482:10.1111/j.1365-2672.2006.03107.x 2218:Journal of Clinical Microbiology 2143:10.1128/JCM.40.12.4625-4627.2002 2131:Journal of Clinical Microbiology 1840:in distilled water for 16 years" 1738:Journal of Clinical Microbiology 1587:10.1128/JCM.43.10.5359-5361.2005 1575:Journal of Clinical Microbiology 808:Note: + = Positive, – =Negative 67: 4523:Human granulocytic anaplasmosis 3745:"The BpeAB-OprB efflux pump of 3545:10.1128/IAI.68.9.5377-5384.2000 2470:Journal of Applied Microbiology 1519:Journal of Medical Microbiology 4555:Ehrlichiosis ewingii infection 2631:10.1128/CDLI.12.4.555-556.2005 1163:VirginiaTech Pathogen Database 1069:bacterium (bacterium with the 876:infection in humans is called 558:are shown in the Table below. 1: 4371:Flinders Island spotted fever 3743:Mima T, Schweizer HP (2010). 3280:10.1016/j.micpath.2004.01.001 3118:10.1016/S0255-0857(21)01773-4 2990:10.1016/S0140-6736(89)90768-X 1387:10.1128/CMR.18.2.383-416.2005 1375:Clinical Microbiology Reviews 1262:10.1016/S0035-9203(08)70002-6 451:Laboratory identification of 5541:Stenotrophomonas maltophilia 4865:Burkholderia cepacia complex 4301:Rocky Mountain spotted fever 3753:Antimicrob. Agents Chemother 3438:10.1371/journal.ppat.1000725 3383:10.1371/journal.ppat.1000178 3325:10.1371/journal.ppat.1000845 3173:10.1371/journal.pntd.0000519 2769:10.1128/JB.55.1.115-126.1948 1971:from contaminated specimens" 1944:10.1016/j.trstmh.2011.10.007 1856:10.1016/j.trstmh.2011.06.004 1330:10.1016/j.trstmh.2011.06.004 895:The antibiotic of choice is 5202:Far East scarlet-like fever 5196:Yersinia pseudotuberculosis 4812:Chromobacteriosis infection 3721:10.1099/mic.0.2007/006585-0 3480:Nature Reviews Microbiology 3211:in the clinical laboratory" 2663:"Burkholderia Pseudomallei" 2425:Antimicrob Agents Chemother 1632:Microbiology and Immunology 228:(Whitmore 1913) Haynes 1957 5917: 5901:Bacteria described in 1993 3918:Burkholderia pseudomallei. 3816:10.1038/s41541-021-00281-z 3417:"Within-host evolution of 3264:Burkholderia thailandensis 3099:Burkholderia pseudomallei: 2822:10.1016/j.jhin.2010.06.026 2804:Burkholderia pseudomallei, 2592:10.1016/j.ijmm.2011.04.017 2022:Burkholderia pseudomallei. 1891:from clinical specimens". 1785:Burkholderia pseudomallei. 1622:Burkholderia thailandensis 1082:Burkholderia pseudomoallei 1045:gene deletion mutants are 888: 866: 639: 5837:burkholderia-pseudomallei 5745:Burkholderia pseudomallei 5715:Burkholderia pseudomallei 5002:Hemolytic-uremic syndrome 4837:Burkholderia pseudomallei 4806:Chromobacterium violaceum 4736:Meningococcal septicaemia 4517:Anaplasma phagocytophilum 4136:Burkholderia pseudomallei 4081:Burkholderia pseudomallei 3979:Burkholderia pseudomallei 3868:10.1007/978-3-031-24355-4 3747:Burkholderia pseudomallei 3702:Burkholderia pseudomallei 3637:Burkholderia pseudomallei 3527:Burkholderia pseudomallei 3474:Burkholderia pseudomallei 3419:Burkholderia pseudomallei 3364:Burkholderia pseudomallei 3306:Burkholderia pseudomallei 3260:Burkholderia pseudomallei 3154:Burkholderia pseudomallei 3054:Burkholderia pseudomallei 3021:Burkholderia pseudomallei 2751:Malleomyces pseudomallei: 2566:Burkholderia pseudomallei 2515:Burkholderia pseudomallei 2419:Burkholderia pseudomallei 2366:Burkholderia pseudomallei 2265:Burkholderia pseudomallei 2212:Burkholderia pseudomallei 2125:Burkholderia pseudomallei 2089:10.1080/00313029800169685 2073:Burkholderia pseudomallei 1969:Burkholderia pseudomallei 1928:Burkholderia pseudomallei 1905:10.3109/00313027909061954 1838:Burkholderia pseudomallei 1711:10.4269/ajtmh.1968.17.183 1626:Burkholderia pseudomallei 1624:) and arabinose-negative 1569:Burkholderia pseudomallei 1565:Burkholderia pseudomallei 1532:10.1099/00222615-46-7-557 1462:Burkholderia pseudomallei 1205:10.1038/nmicrobiol.2015.8 1157:Burkholderia pseudomallei 977:Burkholderia pseudomallei 963:Burkholderia pseudomallei 874:Burkholderia pseudomallei 817:Burkholderia pseudomallei 755: 737: 621:Physiological characters 620: 610:Morphological characters 574: 556:Burkholderia pseudomallei 487:Chromobacterium violaceum 367:Burkholderia pseudomallei 350:). Bacteria produce both 304:Burkholderia pseudomallei 285:Burkholderia pseudomallei 238:Burkholderia pseudomallei 214:Loefflerella pseudomallei 203:Stanton and Fletcher 1921 187: 180: 163:Burkholderia pseudomallei 159: 152: 64:Scientific classification 62: 52:Burkholderia pseudomallei 50: 41: 36:Burkholderia pseudomallei 34: 5477:Plesiomonas shigelloides 5259:Brazilian purpuric fever 4876:Bordetella parapertussis 4665:Bartonella bacilliformis 4484:Flea-borne spotted fever 4414:Rickettsia aeschlimannii 4407:Rickettsia aeschlimannii 4399:American tick bite fever 3209:Pseudomonas pseudomallei 2333:10.1586/14787210.4.3.445 1932:Trans R Soc Trop Med Hyg 1889:Pseudomonas pseudomallei 1844:Trans R Soc Trop Med Hyg 985:type VI secretion system 244:Pseudomonas pseudomallei 225:Pseudomonas pseudomallei 221:Pfeiferella pseudomallei 207:Malleomyces pseudomallei 5645:Guillain–BarrĂ© syndrome 5561:Cardiobacterium hominis 5521:Acinetobacter baumannii 5463:Vibrio parahaemolyticus 5182:Yersinia enterocolitica 4949:Klebsiella granulomatis 4385:African tick bite fever 4343:North Asian tick typhus 4089:. NIAID. Archived from 4034:Analytical Biochemistry 3667:10.1126/science.1211915 1481:10.1186/1471-2180-10-28 1065:in minimal media. The Δ 667:Oxidative-Fermentative 640:Biochemical characters 5497:Pseudomonas aeruginosa 5415:Francisella tularensis 5374:Legionella longbeachae 5370:Legionella pneumophila 5012:Enterobacter aerogenes 4657:Bacillary angiomatosis 4451:Orientia tsutsugamushi 4357:Queensland tick typhus 4329:Japanese spotted fever 4263:Flying squirrel typhus 4046:10.1006/abio.1996.0430 3924:Appl Environ Microbiol 3582:Infection and Immunity 3268:Microbial Pathogenesis 3105:Indian J Med Microbiol 3060:J Antimicrob Chemother 833:potassium permanganate 499:Pseudomonas aeruginosa 217:Brindle and Cowan 1951 5514:Moraxella catarrhalis 5380:Legionnaires' disease 5301:Pasteurella multocida 4931:Klebsiella pneumoniae 4728:Meningococcal disease 4535:Ehrlichia chaffeensis 4295:Rickettsia rickettsii 4259:Brill–Zinsser disease 4249:Rickettsia prowazekii 4142:NCBI Taxonomy Browser 2937:10.4269/ajtmh.20-0223 1987:10.4269/ajtmh.13-0119 891:Melioidosis treatment 821:benzalkonium chloride 190:Bacillus pseudomallei 5675:Helicobacter cinaedi 5635:Campylobacter jejuni 5588:Aeromonas hydrophila 5470:Vibrio alginolyticus 5121:Shigella dysenteriae 5059:Citrobacter freundii 5016:Enterobacter cloacae 4872:Bordetella pertussis 4351:Rickettsia australis 3997:10.1128/IAI.05044-11 3944:10.1128/AEM.00820-09 3765:10.1128/AAC.01803-09 3594:10.1128/IAI.01367-13 3227:10.1136/jcp.32.5.500 3205:Ashdown, LR (1979). 2879:10.1128/AEM.02180-08 2704:10.1128/JCM.01636-16 2533:10.1128/JCM.02350-06 2437:10.1128/AAC.01842-13 2384:10.1128/JCM.02507-08 2283:10.1128/AAC.43.3.465 2230:10.1128/JCM.00935-07 2180:Morb Mortal Wkly Rep 2040:10.1128/JCM.02008-14 1750:10.1128/JCM.00396-07 1561:Burkholderia cepacia 1113:Burkholderia cepacia 952:B. pseudomallei 925:B. pseudomallei 632:Growth at 6.5% NaCl 524:B. pseudomallei 493:Burkholderia cepacia 442:B. pseudomallei 403:, the organism is a 391:Burkholderia cepacia 145:B. pseudomallei 27:Species of bacterium 5653:Helicobacter pylori 5143:Bacillary dysentery 5088:Salmonella enterica 5036:Serratia marcescens 4955:Granuloma inguinale 4851:Burkholderia mallei 4786:Eikenella corrodens 4634:Bartonella quintana 4626:Cat-scratch disease 4620:Bartonella henselae 4337:Rickettsia sibirica 4323:Rickettsia japonica 3936:2009ApEnM..75.6062N 3659:2011Sci...334..821C 3493:10.1038/nrmicro1385 3207:"Identification of 2871:2009ApEnM..75.2987R 2667:www.antimicrobe.org 2570:Burkholderia mallei 2513:"Identification of 1803:10.1128/JB.01258-06 1193:Nature Microbiology 837:sodium hypochlorite 544:latex agglutination 534:Molecular methods ( 429:test is necessary ( 5641:Campylobacteriosis 5552:Cardiobacteriaceae 5053:Citrobacter koseri 4963:Klebsiella oxytoca 4393:Rickettsia parkeri 4379:Rickettsia africae 4309:Rickettsia conorii 3160:PLOS Negl Trop Dis 3073:10.1093/jac/dki151 2747:Malleomyces mallei 1030:Vaccine candidates 863:Medical importance 723:Nitrate reductase 575:Colony characters 528:P. aeruginosa 522:. The majority of 520:P. aeruginosa 318:-containing ones. 200:Bacterium whitmori 101:Betaproteobacteria 5883: 5882: 5868:Open Tree of Life 5707:Taxon identifiers 5698: 5697: 5694: 5693: 5626:Campylobacterales 5611: 5610: 5592:Aeromonas veronii 5456:Vibrio vulnificus 5388:Coxiella burnetii 5355: 5354: 5281:H. parainfluenzae 5216: 5215: 5212: 5211: 5151:Proteus mirabilis 5098:Paratyphoid fever 4987:Enterohemorrhagic 4907:Enterobacteriales 4892: 4891: 4822: 4821: 4689: 4688: 4685: 4684: 4671:Carrion's disease 4565: 4564: 4549:Ehrlichia ewingii 4498: 4497: 4494: 4493: 4315:Boutonneuse fever 3877:978-3-031-24354-7 3714:(Pt 8): 2689–99. 2984:(8665): 697–701. 2698:(12): 2866–2873. 1975:Am J Trop Med Hyg 1850:(10–2): 598–600. 1119:Microbiol Immunol 829:mercuric chloride 806: 805: 458:Colony morphology 234: 233: 229: 218: 211: 204: 197: 16:(Redirected from 5908: 5896:Burkholderiaceae 5876: 5875: 5863: 5862: 5853: 5852: 5840: 5839: 5827: 5826: 5814: 5813: 5801: 5800: 5788: 5787: 5775: 5774: 5762: 5761: 5749: 5748: 5747: 5734: 5733: 5732: 5702: 5622: 5532:Xanthomonadaceae 5340: 5323:Actinobacillosis 5304: 5237: 5227: 5157:Proteus vulgaris 5075: 4972:Escherichia coli 4918: 4903: 4778: 4709: 4700: 4589:Brucella abortus 4576: 4571:Hyphomicrobiales 4478:Rickettsia felis 4437:Rickettsia akari 4365:Rickettsia honei 4282: 4235:Rickettsia typhi 4222: 4206: 4197: 4173: 4166: 4159: 4150: 4145: 4120: 4118: 4117: 4101: 4099: 4098: 4066: 4065: 4025: 4019: 4018: 4008: 3972: 3966: 3965: 3955: 3903: 3897: 3896: 3894: 3892: 3853: 3847: 3846: 3836: 3818: 3793: 3787: 3786: 3776: 3740: 3734: 3733: 3723: 3695: 3689: 3688: 3678: 3630: 3624: 3623: 3613: 3588:(4): 1436–1444. 3573: 3567: 3566: 3556: 3520: 3514: 3513: 3495: 3467: 3461: 3460: 3450: 3440: 3412: 3406: 3405: 3395: 3385: 3376:(10): e1000178. 3357: 3348: 3347: 3337: 3327: 3298: 3292: 3291: 3255: 3249: 3248: 3238: 3202: 3196: 3195: 3185: 3175: 3147: 3141: 3140: 3130: 3120: 3092: 3086: 3085: 3075: 3047: 3041: 3040: 3025:J Med Assoc Thai 3016: 3010: 3009: 2973: 2967: 2966: 2956: 2931:(5): 1838–1840. 2915: 2909: 2908: 2898: 2865:(9): 2987–2990. 2850: 2844: 2843: 2833: 2797: 2791: 2790: 2780: 2740: 2734: 2733: 2723: 2683: 2677: 2676: 2674: 2673: 2659: 2653: 2652: 2642: 2610: 2604: 2603: 2572:by fluorescence 2561: 2555: 2554: 2544: 2508: 2502: 2501: 2465: 2459: 2458: 2448: 2412: 2406: 2405: 2395: 2372:J Clin Microbiol 2359: 2353: 2352: 2316: 2305: 2304: 2294: 2258: 2252: 2251: 2241: 2205: 2196: 2195: 2171: 2165: 2164: 2154: 2118: 2109: 2108: 2068: 2062: 2061: 2051: 2028:J Clin Microbiol 2015: 2009: 2008: 1998: 1962: 1956: 1955: 1923: 1917: 1916: 1884: 1878: 1877: 1867: 1831: 1825: 1824: 1814: 1778: 1772: 1771: 1761: 1729: 1723: 1722: 1694: 1688: 1687: 1667: 1658: 1657: 1647: 1615: 1609: 1608: 1598: 1554: 1545: 1544: 1534: 1510: 1504: 1503: 1493: 1483: 1455: 1449: 1448: 1441: 1435: 1434: 1423: 1417: 1416: 1406: 1366: 1360: 1359: 1349: 1309: 1303: 1302: 1300: 1298: 1283: 1274: 1273: 1241: 1235: 1234: 1224: 1184: 1178: 1177: 1175: 1174: 1165:. Archived from 1151: 1145: 1144: 1134: 1098: 1016:fluoroquinolones 950:is used to kill 899:. While various 731:ÎČ-Galactosidase 689:Voges-Proskauer 570:Characteristics 561: 431:B. thailandensis 422:B. thailandensis 387:Ashdown's medium 227: 216: 209: 202: 192: 165: 121:Burkholderiaceae 72: 71: 46: 32: 21: 5916: 5915: 5911: 5910: 5909: 5907: 5906: 5905: 5886: 5885: 5884: 5879: 5871: 5866: 5858: 5856: 5848: 5843: 5835: 5830: 5822: 5817: 5809: 5804: 5796: 5791: 5783: 5778: 5770: 5765: 5757: 5752: 5743: 5742: 5737: 5728: 5727: 5722: 5709: 5699: 5690: 5607: 5573: 5546: 5526: 5488:Pseudomonadales 5482: 5442:Vibrio cholerae 5427: 5400: 5351: 5334: 5329: 5298: 5293: 5230: 5208: 5164:Yersinia pestis 5108: 5064: 5021: 4977:Enterotoxigenic 4909: 4888: 4828:Burkholderiales 4818: 4792:Kingella kingae 4774: 4769: 4742: 4681: 4675:Verruga peruana 4601: 4561: 4504:Anaplasmataceae 4490: 4463: 4422: 4276: 4269: 4255:Epidemic typhus 4213: 4186: 4177: 4132: 4115: 4113: 4104: 4096: 4094: 4077: 4074: 4069: 4027: 4026: 4022: 3974: 3973: 3969: 3930:(19): 6062–75. 3905: 3904: 3900: 3890: 3888: 3878: 3862:. p. 329. 3855: 3854: 3850: 3795: 3794: 3790: 3742: 3741: 3737: 3697: 3696: 3692: 3653:(6057): 821–4. 3632: 3631: 3627: 3575: 3574: 3570: 3522: 3521: 3517: 3469: 3468: 3464: 3431:(1): e1000725. 3414: 3413: 3409: 3359: 3358: 3351: 3318:(4): e1000845. 3300: 3299: 3295: 3257: 3256: 3252: 3204: 3203: 3199: 3149: 3148: 3144: 3094: 3093: 3089: 3049: 3048: 3044: 3018: 3017: 3013: 2975: 2974: 2970: 2917: 2916: 2912: 2852: 2851: 2847: 2799: 2798: 2794: 2742: 2741: 2737: 2685: 2684: 2680: 2671: 2669: 2661: 2660: 2656: 2612: 2611: 2607: 2563: 2562: 2558: 2510: 2509: 2505: 2467: 2466: 2462: 2414: 2413: 2409: 2361: 2360: 2356: 2318: 2317: 2308: 2260: 2259: 2255: 2207: 2206: 2199: 2173: 2172: 2168: 2120: 2119: 2112: 2070: 2069: 2065: 2017: 2016: 2012: 1964: 1963: 1959: 1925: 1924: 1920: 1886: 1885: 1881: 1833: 1832: 1828: 1780: 1779: 1775: 1731: 1730: 1726: 1696: 1695: 1691: 1672:Br J Biomed Sci 1669: 1668: 1661: 1617: 1616: 1612: 1581:(10): 5359–61. 1556: 1555: 1548: 1512: 1511: 1507: 1457: 1456: 1452: 1443: 1442: 1438: 1425: 1424: 1420: 1368: 1367: 1363: 1324:(10): 598–600. 1311: 1310: 1306: 1296: 1294: 1285: 1284: 1277: 1243: 1242: 1238: 1186: 1185: 1181: 1172: 1170: 1153: 1152: 1148: 1125:(12): 1251–75. 1100: 1099: 1095: 1091: 1079: 1051:diaminopimelate 1032: 1004:aminoglycosides 996:B. pseudomallei 989:B. pseudomallei 971:genomic islands 960: 909:chloramphenicol 893: 887: 871: 865: 849:B. pseudomallei 814: 756:Utilization of 707: 616:Rod (Variable) 552: 550:Characteristics 513:B. pseudomallei 504:B. pseudomallei 453:B. pseudomallei 435:B. pseudomallei 364: 274:B. pseudomallei 241:(also known as 223: 219: 212: 205: 198: 176: 170: 169:(Whitmore 1913) 167: 161: 148: 111:Burkholderiales 66: 28: 23: 22: 18:B. pseudomallei 15: 12: 11: 5: 5914: 5912: 5904: 5903: 5898: 5888: 5887: 5881: 5880: 5878: 5877: 5864: 5854: 5841: 5828: 5815: 5802: 5789: 5776: 5763: 5750: 5735: 5719: 5717: 5711: 5710: 5705: 5696: 5695: 5692: 5691: 5689: 5688: 5687: 5686: 5671: 5670: 5669: 5667:Gastric cancer 5649: 5648: 5647: 5630: 5628: 5619: 5613: 5612: 5609: 5608: 5606: 5605: 5604: 5603: 5583: 5581: 5575: 5574: 5572: 5571: 5570: 5569: 5556: 5554: 5548: 5547: 5545: 5544: 5536: 5534: 5528: 5527: 5525: 5524: 5517: 5510: 5509: 5508: 5492: 5490: 5484: 5483: 5481: 5480: 5473: 5466: 5459: 5452: 5451: 5450: 5437: 5435: 5429: 5428: 5426: 5425: 5424: 5423: 5410: 5408: 5402: 5401: 5399: 5398: 5397: 5396: 5384: 5383: 5382: 5365: 5363: 5357: 5356: 5353: 5352: 5350: 5349: 5343: 5341: 5331: 5330: 5328: 5327: 5326: 5325: 5317:Actinobacillus 5313: 5311:Pasteurellosis 5307: 5305: 5295: 5294: 5292: 5291: 5290: 5289: 5277: 5276: 5275: 5263: 5262: 5261: 5256: 5240: 5238: 5224: 5222:Pasteurellales 5218: 5217: 5214: 5213: 5210: 5209: 5207: 5206: 5205: 5204: 5192: 5191: 5190: 5178: 5177: 5176: 5174:Bubonic plague 5160: 5147: 5146: 5145: 5116: 5114: 5110: 5109: 5107: 5106: 5105: 5104: 5083: 5081: 5072: 5066: 5065: 5063: 5062: 5049: 5048: 5047: 5031: 5029: 5023: 5022: 5020: 5019: 5007: 5006: 5005: 5004: 4994: 4989: 4984: 4982:Enteroinvasive 4979: 4967: 4966: 4959: 4958: 4957: 4945: 4944: 4943: 4926: 4924: 4915: 4900: 4894: 4893: 4890: 4889: 4887: 4886: 4885: 4884: 4868: 4861: 4860: 4859: 4847: 4846: 4845: 4832: 4830: 4824: 4823: 4820: 4819: 4817: 4816: 4815: 4814: 4802: 4801: 4800: 4781: 4779: 4771: 4770: 4768: 4767: 4766: 4765: 4752: 4750: 4744: 4743: 4741: 4740: 4739: 4738: 4717: 4715: 4706: 4697: 4691: 4690: 4687: 4686: 4683: 4682: 4680: 4679: 4678: 4677: 4661: 4660: 4659: 4644: 4643: 4642: 4630: 4629: 4628: 4611: 4609: 4607:Bartonellaceae 4603: 4602: 4600: 4599: 4598: 4597: 4584: 4582: 4573: 4567: 4566: 4563: 4562: 4560: 4559: 4558: 4557: 4545: 4544: 4543: 4531: 4530: 4529: 4508: 4506: 4500: 4499: 4496: 4495: 4492: 4491: 4489: 4488: 4487: 4486: 4473: 4471: 4465: 4464: 4462: 4461: 4460: 4459: 4447: 4446: 4445: 4443:Rickettsialpox 4432: 4430: 4424: 4423: 4421: 4420: 4419: 4418: 4403: 4402: 4401: 4389: 4388: 4387: 4375: 4374: 4373: 4361: 4360: 4359: 4347: 4346: 4345: 4333: 4332: 4331: 4319: 4318: 4317: 4305: 4304: 4303: 4290: 4288: 4279: 4271: 4270: 4268: 4267: 4266: 4265: 4245: 4244: 4243: 4230: 4228: 4219: 4210:Rickettsiaceae 4203: 4194: 4188: 4187: 4180:Pseudomonadota 4178: 4176: 4175: 4168: 4161: 4153: 4147: 4146: 4130: 4121: 4102: 4073: 4072:External links 4070: 4068: 4067: 4020: 3991:(10): 4010–8. 3967: 3898: 3876: 3848: 3788: 3759:(8): 3113–20. 3735: 3690: 3625: 3568: 3539:(9): 5377–84. 3515: 3462: 3407: 3349: 3293: 3250: 3197: 3142: 3087: 3066:(6): 1029–31. 3042: 3011: 2968: 2910: 2845: 2792: 2763:(1): 115–126. 2735: 2678: 2654: 2605: 2556: 2503: 2460: 2407: 2378:(5): 1578–80. 2354: 2306: 2253: 2224:(11): 3774–6. 2197: 2166: 2137:(12): 4625–7. 2110: 2075:by API 20NE". 2063: 2010: 1957: 1918: 1879: 1826: 1773: 1744:(5): 1669–70. 1724: 1689: 1659: 1610: 1546: 1505: 1450: 1436: 1418: 1381:(2): 383–416. 1361: 1304: 1275: 1236: 1179: 1146: 1092: 1090: 1087: 1078: 1077:Transformation 1075: 1031: 1028: 959: 956: 917:co-trimoxazole 889:Main article: 886: 883: 867:Main article: 864: 861: 845:glutaraldehyde 813: 810: 804: 803: 800: 796: 795: 792: 788: 787: 784: 780: 779: 776: 772: 771: 768: 764: 763: 760: 757: 753: 752: 750: 746: 745: 742: 739: 738:Hydrolysis of 735: 734: 732: 728: 727: 724: 720: 719: 717: 713: 712: 709: 705: 701: 700: 697: 693: 692: 690: 686: 685: 683: 679: 678: 675: 671: 670: 668: 664: 663: 660: 656: 655: 652: 648: 647: 644: 643:Gram staining 641: 637: 636: 633: 629: 628: 625: 622: 618: 617: 614: 611: 607: 606: 603: 599: 598: 595: 591: 590: 587: 583: 582: 579: 576: 572: 571: 568: 565: 551: 548: 379:MacConkey agar 363: 362:Identification 360: 278:laboratory use 232: 231: 185: 184: 178: 177: 168: 157: 156: 150: 149: 142: 140: 136: 135: 128: 124: 123: 118: 114: 113: 108: 104: 103: 98: 94: 93: 91:Pseudomonadota 88: 84: 83: 78: 74: 73: 60: 59: 56:Ashdown's agar 48: 47: 39: 38: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 5913: 5902: 5899: 5897: 5894: 5893: 5891: 5874: 5869: 5865: 5861: 5855: 5851: 5846: 5842: 5838: 5833: 5829: 5825: 5820: 5816: 5812: 5807: 5803: 5799: 5794: 5790: 5786: 5781: 5777: 5773: 5768: 5764: 5760: 5755: 5751: 5746: 5740: 5736: 5731: 5725: 5721: 5720: 5718: 5716: 5712: 5708: 5703: 5685: 5683: 5679: 5678: 5677: 5676: 5672: 5668: 5664: 5663:MALT lymphoma 5660: 5657: 5656: 5655: 5654: 5650: 5646: 5642: 5639: 5638: 5637: 5636: 5632: 5631: 5629: 5627: 5623: 5620: 5618: 5614: 5602: 5600: 5596: 5595: 5594: 5593: 5589: 5585: 5584: 5582: 5580: 5579:Aeromonadales 5576: 5568: 5565: 5564: 5563: 5562: 5558: 5557: 5555: 5553: 5549: 5543: 5542: 5538: 5537: 5535: 5533: 5529: 5523: 5522: 5518: 5516: 5515: 5511: 5507: 5505: 5501: 5500: 5499: 5498: 5494: 5493: 5491: 5489: 5485: 5479: 5478: 5474: 5472: 5471: 5467: 5465: 5464: 5460: 5458: 5457: 5453: 5449: 5446: 5445: 5444: 5443: 5439: 5438: 5436: 5434: 5430: 5422: 5419: 5418: 5417: 5416: 5412: 5411: 5409: 5407: 5406:Thiotrichales 5403: 5395: 5392: 5391: 5390: 5389: 5385: 5381: 5378: 5377: 5376: 5375: 5371: 5367: 5366: 5364: 5362: 5361:Legionellales 5358: 5348: 5345: 5344: 5342: 5339: 5338: 5332: 5324: 5321: 5320: 5319: 5318: 5314: 5312: 5309: 5308: 5306: 5303: 5302: 5296: 5288: 5285: 5284: 5283: 5282: 5278: 5274: 5271: 5270: 5269: 5268: 5264: 5260: 5257: 5255: 5253: 5249: 5248: 5247: 5246: 5245:H. influenzae 5242: 5241: 5239: 5236: 5234: 5228: 5225: 5223: 5219: 5203: 5200: 5199: 5198: 5197: 5193: 5189: 5186: 5185: 5184: 5183: 5179: 5175: 5171: 5168: 5167: 5166: 5165: 5161: 5159: 5158: 5153: 5152: 5148: 5144: 5140: 5137: 5136: 5135: 5134: 5130: 5126: 5122: 5118: 5117: 5115: 5111: 5103: 5102:Salmonellosis 5099: 5095: 5094:Typhoid fever 5092: 5091: 5090: 5089: 5085: 5084: 5082: 5080: 5076: 5073: 5071: 5067: 5061: 5060: 5055: 5054: 5050: 5046: 5044: 5040: 5039: 5038: 5037: 5033: 5032: 5030: 5028: 5024: 5018: 5017: 5013: 5009: 5008: 5003: 5000: 4999: 4998: 4995: 4993: 4990: 4988: 4985: 4983: 4980: 4978: 4974: 4973: 4969: 4968: 4965: 4964: 4960: 4956: 4953: 4952: 4951: 4950: 4946: 4942: 4938: 4937:Rhinoscleroma 4935: 4934: 4933: 4932: 4928: 4927: 4925: 4923: 4919: 4916: 4913: 4908: 4904: 4901: 4899: 4895: 4883: 4880: 4879: 4878: 4877: 4873: 4869: 4867: 4866: 4862: 4858: 4855: 4854: 4853: 4852: 4848: 4844: 4841: 4840: 4839: 4838: 4834: 4833: 4831: 4829: 4825: 4813: 4810: 4809: 4808: 4807: 4803: 4799: 4796: 4795: 4794: 4793: 4788: 4787: 4783: 4782: 4780: 4777: 4772: 4764: 4761: 4760: 4759: 4758: 4754: 4753: 4751: 4749: 4745: 4737: 4733: 4729: 4726: 4725: 4724: 4723: 4719: 4718: 4716: 4714: 4710: 4707: 4705: 4701: 4698: 4696: 4692: 4676: 4672: 4669: 4668: 4667: 4666: 4662: 4658: 4655: 4654: 4653: 4649: 4645: 4641: 4638: 4637: 4636: 4635: 4631: 4627: 4624: 4623: 4622: 4621: 4616: 4615:Bartonellosis 4613: 4612: 4610: 4608: 4604: 4596: 4593: 4592: 4591: 4590: 4586: 4585: 4583: 4581: 4577: 4574: 4572: 4568: 4556: 4553: 4552: 4551: 4550: 4546: 4542: 4539: 4538: 4537: 4536: 4532: 4528: 4524: 4521: 4520: 4519: 4518: 4513: 4510: 4509: 4507: 4505: 4501: 4485: 4482: 4481: 4480: 4479: 4475: 4474: 4472: 4470: 4466: 4458: 4455: 4454: 4453: 4452: 4448: 4444: 4441: 4440: 4439: 4438: 4434: 4433: 4431: 4429: 4425: 4417: 4415: 4411: 4410: 4409: 4408: 4404: 4400: 4397: 4396: 4395: 4394: 4390: 4386: 4383: 4382: 4381: 4380: 4376: 4372: 4369: 4368: 4367: 4366: 4362: 4358: 4355: 4354: 4353: 4352: 4348: 4344: 4341: 4340: 4339: 4338: 4334: 4330: 4327: 4326: 4325: 4324: 4320: 4316: 4313: 4312: 4311: 4310: 4306: 4302: 4299: 4298: 4297: 4296: 4292: 4291: 4289: 4287: 4283: 4280: 4278: 4272: 4264: 4260: 4256: 4253: 4252: 4251: 4250: 4246: 4242: 4241:Murine typhus 4239: 4238: 4237: 4236: 4232: 4231: 4229: 4227: 4223: 4220: 4217: 4216:Rickettsioses 4211: 4207: 4204: 4202: 4201:Rickettsiales 4198: 4195: 4193: 4189: 4185: 4181: 4174: 4169: 4167: 4162: 4160: 4155: 4154: 4151: 4143: 4139: 4137: 4131: 4128: 4125: 4122: 4112:on 2009-09-27 4111: 4107: 4103: 4093:on 2011-08-24 4092: 4088: 4084: 4082: 4076: 4075: 4071: 4063: 4059: 4055: 4051: 4047: 4043: 4039: 4035: 4031: 4024: 4021: 4016: 4012: 4007: 4002: 3998: 3994: 3990: 3986: 3982: 3980: 3971: 3968: 3963: 3959: 3954: 3949: 3945: 3941: 3937: 3933: 3929: 3925: 3921: 3919: 3915: 3911: 3902: 3899: 3887: 3883: 3879: 3873: 3869: 3865: 3861: 3860: 3852: 3849: 3844: 3840: 3835: 3830: 3826: 3822: 3817: 3812: 3808: 3804: 3800: 3792: 3789: 3784: 3780: 3775: 3770: 3766: 3762: 3758: 3754: 3750: 3748: 3739: 3736: 3731: 3727: 3722: 3717: 3713: 3709: 3705: 3703: 3694: 3691: 3686: 3682: 3677: 3672: 3668: 3664: 3660: 3656: 3652: 3648: 3644: 3642: 3638: 3629: 3626: 3621: 3617: 3612: 3607: 3603: 3599: 3595: 3591: 3587: 3583: 3579: 3572: 3569: 3564: 3560: 3555: 3550: 3546: 3542: 3538: 3534: 3533:Infect. Immun 3530: 3528: 3519: 3516: 3511: 3507: 3503: 3499: 3494: 3489: 3486:(4): 272–82. 3485: 3481: 3477: 3475: 3466: 3463: 3458: 3454: 3449: 3444: 3439: 3434: 3430: 3426: 3422: 3420: 3411: 3408: 3403: 3399: 3394: 3389: 3384: 3379: 3375: 3371: 3367: 3365: 3356: 3354: 3350: 3345: 3341: 3336: 3331: 3326: 3321: 3317: 3313: 3309: 3307: 3297: 3294: 3289: 3285: 3281: 3277: 3273: 3269: 3265: 3261: 3254: 3251: 3246: 3242: 3237: 3232: 3228: 3224: 3220: 3216: 3215:J Clin Pathol 3212: 3210: 3201: 3198: 3193: 3189: 3184: 3179: 3174: 3169: 3165: 3161: 3157: 3155: 3146: 3143: 3138: 3134: 3129: 3124: 3119: 3114: 3110: 3106: 3102: 3100: 3091: 3088: 3083: 3079: 3074: 3069: 3065: 3061: 3057: 3055: 3046: 3043: 3038: 3034: 3031:(8): 856–60. 3030: 3026: 3022: 3015: 3012: 3007: 3003: 2999: 2995: 2991: 2987: 2983: 2979: 2972: 2969: 2964: 2960: 2955: 2950: 2946: 2942: 2938: 2934: 2930: 2926: 2922: 2914: 2911: 2906: 2902: 2897: 2892: 2888: 2884: 2880: 2876: 2872: 2868: 2864: 2860: 2856: 2849: 2846: 2841: 2837: 2832: 2827: 2823: 2819: 2815: 2811: 2810:J Hosp Infect 2807: 2805: 2796: 2793: 2788: 2784: 2779: 2774: 2770: 2766: 2762: 2758: 2754: 2752: 2748: 2739: 2736: 2731: 2727: 2722: 2717: 2713: 2709: 2705: 2701: 2697: 2693: 2689: 2682: 2679: 2668: 2664: 2658: 2655: 2650: 2646: 2641: 2636: 2632: 2628: 2624: 2620: 2616: 2609: 2606: 2601: 2597: 2593: 2589: 2586:(7): 585–90. 2585: 2581: 2580: 2575: 2571: 2567: 2560: 2557: 2552: 2548: 2543: 2538: 2534: 2530: 2527:(3): 1045–8. 2526: 2522: 2518: 2516: 2507: 2504: 2499: 2495: 2491: 2487: 2483: 2479: 2475: 2471: 2464: 2461: 2456: 2452: 2447: 2442: 2438: 2434: 2430: 2426: 2422: 2420: 2411: 2408: 2403: 2399: 2394: 2389: 2385: 2381: 2377: 2373: 2369: 2367: 2358: 2355: 2350: 2346: 2342: 2338: 2334: 2330: 2327:(3): 445–55. 2326: 2322: 2315: 2313: 2311: 2307: 2302: 2298: 2293: 2288: 2284: 2280: 2277:(3): 465–70. 2276: 2272: 2268: 2266: 2257: 2254: 2249: 2245: 2240: 2235: 2231: 2227: 2223: 2219: 2215: 2213: 2210:"Accuracy of 2204: 2202: 2198: 2193: 2189: 2186:(32): 873–6. 2185: 2181: 2177: 2170: 2167: 2162: 2158: 2153: 2148: 2144: 2140: 2136: 2132: 2128: 2126: 2117: 2115: 2111: 2106: 2102: 2098: 2094: 2090: 2086: 2082: 2078: 2074: 2067: 2064: 2059: 2055: 2050: 2045: 2041: 2037: 2033: 2029: 2025: 2023: 2014: 2011: 2006: 2002: 1997: 1992: 1988: 1984: 1981:(5): 973–82. 1980: 1976: 1972: 1970: 1961: 1958: 1953: 1949: 1945: 1941: 1937: 1933: 1929: 1922: 1919: 1914: 1910: 1906: 1902: 1898: 1894: 1890: 1883: 1880: 1875: 1871: 1866: 1861: 1857: 1853: 1849: 1845: 1841: 1839: 1836:"Survival of 1830: 1827: 1822: 1818: 1813: 1808: 1804: 1800: 1797:(3): 807–17. 1796: 1792: 1788: 1786: 1777: 1774: 1769: 1765: 1760: 1755: 1751: 1747: 1743: 1739: 1735: 1728: 1725: 1720: 1716: 1712: 1708: 1705:(2): 183–91. 1704: 1700: 1693: 1690: 1685: 1681: 1678:(4): 249–53. 1677: 1673: 1666: 1664: 1660: 1655: 1651: 1646: 1641: 1638:(7): 625–30. 1637: 1633: 1629: 1627: 1623: 1614: 1611: 1606: 1602: 1597: 1592: 1588: 1584: 1580: 1576: 1572: 1570: 1566: 1562: 1553: 1551: 1547: 1542: 1538: 1533: 1528: 1525:(7): 557–63. 1524: 1520: 1516: 1509: 1506: 1501: 1497: 1492: 1487: 1482: 1477: 1473: 1469: 1468:BMC Microbiol 1465: 1463: 1454: 1451: 1446: 1445:"Melioidosis" 1440: 1437: 1433:. 2022-07-27. 1432: 1428: 1427:"Melioidosis" 1422: 1419: 1414: 1410: 1405: 1400: 1396: 1392: 1388: 1384: 1380: 1376: 1372: 1365: 1362: 1357: 1353: 1348: 1343: 1339: 1335: 1331: 1327: 1323: 1319: 1315: 1308: 1305: 1293: 1289: 1282: 1280: 1276: 1271: 1267: 1263: 1259: 1255: 1251: 1247: 1240: 1237: 1232: 1228: 1223: 1218: 1214: 1210: 1206: 1202: 1198: 1194: 1190: 1183: 1180: 1169:on 2006-09-01 1168: 1164: 1160: 1158: 1150: 1147: 1142: 1138: 1133: 1128: 1124: 1120: 1116: 1114: 1110: 1106: 1103:"Proposal of 1097: 1094: 1088: 1086: 1083: 1076: 1074: 1072: 1068: 1064: 1060: 1056: 1052: 1048: 1044: 1042: 1035: 1029: 1027: 1025: 1021: 1017: 1013: 1012:tetracyclines 1009: 1005: 1001: 997: 993: 990: 986: 982: 978: 974: 972: 967: 964: 957: 955: 953: 949: 945: 941: 936: 934: 933:agar dilution 930: 926: 922: 918: 914: 910: 906: 902: 898: 892: 884: 882: 879: 875: 870: 862: 860: 859:irradiation. 858: 854: 850: 846: 842: 838: 834: 830: 826: 822: 818: 811: 809: 801: 798: 797: 793: 790: 789: 785: 782: 781: 777: 774: 773: 769: 766: 765: 761: 758: 754: 751: 748: 747: 743: 740: 736: 733: 730: 729: 725: 722: 721: 718: 715: 714: 710: 708:S Production 703: 702: 698: 695: 694: 691: 688: 687: 684: 681: 680: 676: 673: 672: 669: 666: 665: 661: 658: 657: 653: 650: 649: 645: 642: 638: 634: 631: 630: 626: 623: 619: 615: 612: 609: 608: 604: 601: 600: 596: 593: 592: 588: 585: 584: 580: 577: 573: 569: 566: 563: 562: 559: 557: 549: 547: 545: 541: 537: 532: 529: 525: 521: 516: 514: 510: 505: 501: 500: 495: 494: 489: 488: 482: 480: 476: 472: 468: 464: 459: 454: 449: 447: 443: 438: 436: 432: 428: 424: 423: 418: 414: 410: 406: 405:Gram-negative 402: 401:Gram staining 398: 397: 392: 388: 384: 380: 376: 372: 368: 361: 359: 357: 353: 349: 345: 341: 337: 333: 329: 325: 324: 319: 317: 313: 309: 305: 301: 299: 295: 291: 286: 281: 279: 275: 270: 266: 262: 258: 254: 250: 249:Gram-negative 246: 245: 240: 239: 230: 226: 222: 215: 208: 201: 195: 191: 186: 183: 179: 174: 166: 164: 158: 155: 154:Binomial name 151: 147: 146: 141: 138: 137: 134: 133: 129: 126: 125: 122: 119: 116: 115: 112: 109: 106: 105: 102: 99: 96: 95: 92: 89: 86: 85: 82: 79: 76: 75: 70: 65: 61: 57: 53: 49: 45: 40: 37: 33: 30: 19: 5714: 5682:Helicobacter 5681: 5673: 5659:Peptic ulcer 5651: 5633: 5598: 5586: 5559: 5539: 5519: 5512: 5503: 5495: 5475: 5468: 5461: 5454: 5440: 5433:Vibrionaceae 5413: 5386: 5368: 5335: 5315: 5299: 5279: 5265: 5251: 5243: 5231: 5194: 5180: 5162: 5155: 5149: 5119: 5086: 5057: 5051: 5042: 5034: 5010: 4970: 4961: 4947: 4929: 4870: 4863: 4849: 4836: 4835: 4804: 4790: 4784: 4775: 4755: 4720: 4704:Neisseriales 4663: 4651: 4647: 4640:Trench fever 4632: 4618: 4587: 4580:Brucellaceae 4547: 4533: 4527:Anaplasmosis 4515: 4512:Ehrlichiosis 4476: 4457:Scrub typhus 4449: 4435: 4413: 4405: 4391: 4377: 4363: 4349: 4335: 4321: 4307: 4293: 4247: 4233: 4182:-associated 4141: 4135: 4127:Burkholderia 4126: 4114:. Retrieved 4110:the original 4095:. Retrieved 4091:the original 4086: 4080: 4040:(1): 73–76. 4037: 4033: 4023: 3988: 3985:Infect Immun 3984: 3978: 3970: 3927: 3923: 3917: 3913: 3909: 3901: 3889:. Retrieved 3858: 3851: 3806: 3803:npj Vaccines 3802: 3791: 3756: 3752: 3746: 3738: 3711: 3708:Microbiology 3707: 3701: 3693: 3650: 3646: 3640: 3636: 3628: 3585: 3581: 3571: 3536: 3532: 3526: 3518: 3483: 3479: 3473: 3465: 3428: 3424: 3418: 3410: 3373: 3369: 3363: 3315: 3311: 3305: 3296: 3274:(5): 287–9. 3271: 3267: 3263: 3259: 3253: 3221:(5): 500–4. 3218: 3214: 3208: 3200: 3163: 3159: 3153: 3145: 3108: 3104: 3098: 3090: 3063: 3059: 3053: 3045: 3028: 3024: 3020: 3014: 2981: 2977: 2971: 2928: 2924: 2913: 2862: 2858: 2848: 2816:(2): 183–4. 2813: 2809: 2803: 2795: 2760: 2756: 2750: 2746: 2738: 2695: 2691: 2681: 2670:. Retrieved 2666: 2657: 2625:(4): 555–6. 2622: 2618: 2608: 2583: 2577: 2573: 2569: 2565: 2559: 2524: 2520: 2514: 2506: 2476:(3): 852–9. 2473: 2469: 2463: 2431:(1): 162–6. 2428: 2424: 2418: 2410: 2375: 2371: 2365: 2357: 2324: 2320: 2274: 2270: 2264: 2256: 2221: 2217: 2211: 2183: 2179: 2169: 2134: 2130: 2124: 2080: 2076: 2072: 2066: 2034:(3): 910–4. 2031: 2027: 2021: 2013: 1978: 1974: 1968: 1960: 1938:(2): 131–3. 1935: 1931: 1927: 1921: 1899:(2): 293–7. 1896: 1892: 1888: 1882: 1847: 1843: 1837: 1829: 1794: 1790: 1784: 1776: 1741: 1737: 1727: 1702: 1698: 1692: 1675: 1671: 1635: 1631: 1625: 1621: 1613: 1578: 1574: 1568: 1564: 1563:medium, and 1560: 1522: 1518: 1508: 1471: 1467: 1461: 1453: 1439: 1430: 1421: 1378: 1374: 1364: 1321: 1317: 1307: 1295:. Retrieved 1292:The Guardian 1291: 1253: 1249: 1239: 1199:(1): 15008. 1196: 1192: 1182: 1171:. Retrieved 1167:the original 1162: 1156: 1149: 1122: 1118: 1112: 1108: 1105:Burkholderia 1104: 1096: 1081: 1080: 1070: 1066: 1040: 1036: 1033: 1023: 1007: 995: 994: 988: 976: 975: 968: 962: 961: 951: 937: 924: 920: 904: 894: 873: 872: 848: 816: 815: 812:Disinfection 807: 555: 553: 539: 533: 527: 523: 519: 517: 512: 503: 497: 491: 485: 483: 479:mycobacteria 462: 452: 450: 446:Wayson stain 441: 439: 434: 430: 420: 416: 394: 390: 366: 365: 321: 320: 303: 302: 298:bioterrorism 284: 282: 273: 243: 242: 237: 236: 235: 224: 220: 213: 206: 199: 189: 188: 172: 162: 160: 144: 143: 132:Burkholderia 131: 54:colonies on 51: 35: 29: 5739:Wikispecies 5504:Pseudomonas 5252:Haemophilus 5233:Haemophilus 5188:Yersiniosis 5139:Shigellosis 4843:Melioidosis 4652:B. quintana 4648:B. henselae 4595:Brucellosis 3425:PLOS Pathog 3370:PLOS Pathog 3312:PLOS Pathog 3166:(9): e519. 3111:(1): 88–9. 2757:J Bacteriol 2083:(1): 62–4. 1791:J Bacteriol 1109:Pseudomonas 1047:auxotrophic 1000:efflux pump 913:doxycycline 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2077:Pathology 1893:Pathology 1395:0893-8512 1338:0035-9203 1256:: S1–S4. 1213:2058-5276 1063:threonine 948:Kanamycin 802:Variable 799:Mannitol 759:Glycerol 674:Motility 659:Catalase 624:Motility 605:Multiple 427:arabinose 425:using an 417:B. mallei 396:B. mallei 340:galactose 261:bacterium 171:Yabuuchi 139:Species: 5798:10435430 5724:Wikidata 5129:flexneri 5043:Serratia 4857:Glanders 4144:. 28450. 4129:resource 4015:21807903 3962:19648360 3843:33514749 3783:20498323 3730:17660433 3685:22076380 3620:24421040 3563:10948167 3510:23909148 3502:16541135 3457:20090837 3402:18927621 3344:20368977 3288:15043863 3192:19771149 3137:19172079 3082:15886263 3037:10998837 3006:28919574 2963:32748772 2905:19270145 2840:20832143 2787:16561426 2730:27654336 2649:15817767 2600:21658996 2551:17251403 2498:24843231 2490:17309636 2455:24145517 2402:19279182 2349:35619761 2341:16771621 2301:10049252 2248:17804660 2192:16915220 2161:12454163 2105:31987728 2058:25588650 2005:24062483 1952:22112687 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1652:  1603:  1593:  1539:  1498:  1488:  1474:: 28. 1411:  1401:  1393:  1354:  1344:  1336:  1268:  1229:  1219:  1211:  1139:  1055:lysine 1018:, and 929:Etests 853:Virkon 839:, 70% 825:iodine 613:Shape 602:Shape 594:Color 589:Round 473:, and 348:starch 332:sugars 257:motile 173:et al. 5850:28450 5811:90893 5793:IRMNG 5567:HACEK 5347:HACEK 5287:HACEK 4798:HACEK 4277:fever 3977:"The 3882:S2CID 3641:eIF4A 3506:S2CID 3002:S2CID 2494:S2CID 2345:S2CID 2292:89145 2101:S2CID 981:actin 843:, 2% 835:, 1% 586:Type 578:Size 567:Test 354:and 5845:NCBI 5832:LPSN 5819:ITIS 5780:GBIF 5759:NXJ9 5113:H2S− 5079:H2S+ 5070:Lac− 4922:Lac+ 4058:PMID 4050:ISSN 4011:PMID 3958:PMID 3914:dapB 3912:and 3893:2023 3872:ISBN 3839:PMID 3821:ISSN 3779:PMID 3726:PMID 3681:PMID 3616:PMID 3598:ISSN 3559:PMID 3498:PMID 3453:PMID 3398:PMID 3340:PMID 3284:PMID 3241:PMID 3188:PMID 3133:PMID 3078:PMID 3033:PMID 2994:PMID 2959:PMID 2941:ISSN 2901:PMID 2883:ISSN 2836:PMID 2783:PMID 2749:and 2726:PMID 2708:ISSN 2645:PMID 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Index

B. pseudomallei

Ashdown's agar
Scientific classification
Edit this classification
Bacteria
Pseudomonadota
Betaproteobacteria
Burkholderiales
Burkholderiaceae
Burkholderia
Binomial name
Synonyms
Whitmore
Gram-negative
aerobic
motile
bacterium
tropical
subtropical
laboratory use
melioidosis
CDC
bioterrorism
flagella
betaine
arginine
In vitro
pH
sugars

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