24:
662:
Sótonyi, P; Merkely, B; Hubay, M; Járay, J; Zima, E; Soós, P; Kovács, A; Szentmáriay, I (February 2004). "Comparative study on cardiotoxic effect of
Tinuvin 770: a light stabilizer of medical plastics in rat model".
499:
Papke, RL; Craig, AG; Heinemann, SF (February 1994). "Inhibition of nicotinic acetylcholine receptors by bis (2,2,6,6-tetramethyl- 4-piperidinyl) sebacate (Tinuvin 770), an additive to medical plastics".
471:
84:
578:
Sótonyi, P; Keller, E; Járay, J; Nemes, B; Benkõ, T; Kovács, A; Tolokán, A; Rajs, I (15 July 2001). "A light stabilizer
Tinuvin 770-induced toxic injury of adult rat cardiac myocytes".
220:
204:
InChI=1S/C28H52N2O4/c1-25(2)17-21(18-26(3,4)29-25)33-23(31)15-13-11-9-10-12-14-16-24(32)34-22-19-27(5,6)30-28(7,8)20-22/h21-22,29-30H,9-20H2,1-8H3
527:
Glossmann, H; Hering, S; Savchenko, A; Berger, W; Friedrich, K; Garcia, ML; Goetz, MA; Liesch, JM; Zink, DL; Kaczorowski, GJ (15 October 1993).
462:
195:
392:
338:
442:
424:
380:
529:"A light stabilizer (Tinuvin 770) that elutes from polypropylene plastic tubes is a potent L-type Ca(2+)-channel blocker"
318:
172:
704:
115:
133:
613:
Krepuska, M; Hubay, M; Zima, E; Kovacs, A; Kekesi, V; Kalasz, H; Szilagyi, B; Merkely, B; Sotonyi, P (2018).
400:
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399:. It is also able to induce dose-dependent hemodynamic alterations. Similar to early
300:
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463:"An industrial chemical is showing up in fentanyl in the U.S., troubling scientists"
376:
161:
630:
533:
Proceedings of the
National Academy of Sciences of the United States of America
665:
Toxicological
Sciences : An Official Journal of the Society of Toxicology
404:
277:
95:
676:
545:
684:
648:
599:
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513:
615:"Hemodynamic Effects of the Light Stabilizer Tinuvin 770 in Dogs In Vivo"
364:
290:
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116:
311:
Except where otherwise noted, data are given for materials in their
83:
73:
23:
228:
CC1(C)CC(CC(C)(C)N1)OC(=O)CCCCCCCCC(=O)OC2CC(C)(C)NC(C)(C)C2
486:"Preparation method of hindered amine light stabilizer 770"
363:
In 2024 it was detected as an adulterant in illicitly sold
502:
The
Journal of Pharmacology and Experimental Therapeutics
305:
81 to 85 °C (178 to 185 °F; 354 to 358 K)
447:
The Center for
Forensic Science Research & Education
160:
425:"Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate"
59:
38:Bis(2,2,6,6-tetramethyl-4-piperidinyl) sebacate
8:
395:. Additionally, it is a potent blocker of
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15:
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460:Alpert Reyes, Emily (16 September 2024).
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474:from the original on 16 September 2024.
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225:
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207:Key: XITRBUPOXXBIJN-UHFFFAOYSA-N
7:
619:The Open Medicinal Chemistry Journal
360:. It is a white crystalline powder.
151:
14:
393:nicotinic acetylcholine receptors
261:
255:
22:
339:hindered amine light stabilizer
315:(at 25 °C , 100 kPa).
580:Forensic Science International
387:Potential medical significance
267:
249:
1:
592:10.1016/s0379-0738(00)00462-x
391:It is capable of inhibiting
631:10.2174/1874104501812010088
731:
341:with the chemical formula
309:
236:
216:
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43:
35:
30:
21:
429:pubchem.ncbi.nlm.nih.gov
401:calcium channel blockers
375:Its production involves
371:Production and reactions
546:10.1073/pnas.90.20.9523
397:L-type calcium channels
381:tetramethylpiperidinol
367:in the United States.
677:10.1093/toxsci/kfh025
403:, it can precipitate
285: g·mol
18:
705:Plastics additives
319:Infobox references
16:
488:. 13 August 2014.
468:Los Angeles Times
327:Chemical compound
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85:Interactive image
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539:(20): 9523–7.
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671:(2): 368–74.
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508:(2): 718–26.
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586:(3): 322–7.
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377:sebacic acid
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330:
329:
44:Identifiers
36:Other names
710:Piperidines
335:Tinuvin 770
237:Properties
699:Categories
411:References
405:adrenergic
295:1.05 g/cm
278:Molar mass
182:6803A71201
96:ChemSpider
72:3D model (
61:52829-07-9
51:CAS Number
625:: 88–97.
407:release.
125:258-207-9
117:EC Number
685:14657520
649:30288180
600:11390147
472:Archived
365:fentanyl
640:6142673
565:8415734
514:8113983
443:"BTMPS"
337:) is a
291:Density
283:480.734
149:PubChem
140:C083752
715:Esters
683:
647:
637:
598:
563:
553:
512:
221:SMILES
162:164282
105:144046
31:Names
17:BTMPS
556:47601
331:BTMPS
196:InChI
74:JSmol
681:PMID
645:PMID
596:PMID
561:PMID
510:PMID
379:and
173:UNII
134:MeSH
673:doi
635:PMC
627:doi
588:doi
584:119
551:PMC
541:doi
506:268
152:CID
701::
679:.
669:77
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623:12
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345:28
259:52
253:28
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543::
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449:.
431:.
357:4
355:O
353:2
351:N
347:H
343:C
271:4
268:O
265:2
262:N
256:H
250:C
76:)
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