301:
180:
43:
287:
A diagnosis of this syndrome is made when an individual has the constellation of the characteristic recurrent neutrophilic dermatosis, flu-like symptoms, arthralgias or arthritis, and myalgias in the setting of a pathology of the bowels that is not best explained by another diagnosis.
401:
Brouard MC, Chavaz P, Borradori L (January 2004). "Acute pustulosis of the legs in diverticulitis with sigmoid stenosis: an overlap between bowel-associated dermatosis-arthritis syndrome and pustular pyoderma gangrenosum".
540:
Jorizzo JL, Schmalstieg FC, Dinehart SM, et al. (April 1984). "Bowel-associated dermatosis-arthritis syndrome. Immune complex-mediated vessel damage and increased neutrophil migration".
616:
109:) and skin changes. It has been reported to occur in up to 20% of patients who had jejunoileal bypass surgery, a form of obesity surgery that is rarely performed today.
488:
Prpić-Massari L, Kastelan M, Brajac I, Cabrijan L, Zamolo G, Massari D (August 2007). "Bowel-associated dermatosis-arthritis syndrome in a patient with appendicitis".
366:
Jorizzo JL, Apisarnthanarax P, Subrt P, et al. (March 1983). "Bowel-bypass syndrome without bowel bypass. Bowel-associated dermatosis-arthritis syndrome".
445:
Slater GH, Kerlin P, Georghiou PR, Fielding GA (January 2004). "Bowel-associated dermatosis-arthritis syndrome after biliopancreatic diversion".
524:
227:
336:
226:. The joint pains in BADAS are typically episodic, migratory and affecting multiple joints. They can affect the small joints (e.g.
223:
171:. Since "bowel bypass syndrome" is not applicable to these cases, the term BADAS was coined by Jorizzo and co-authors in 1984.
275:
into the affected joints and skin. The effect of antibacterial therapy supports a role for bacteria in the disease mechanism (
341:
148:
160:
251:
are thought to cause blood vessel damage, attracting neutrophils into the skin and synovium in BADAS. These
90:
195:
264:
144:
are an alternative. Surgical repair of the normal bowel transit, where possible, can be effective.
470:
427:
207:
86:
51:
592:
557:
520:
497:
462:
419:
383:
167:, also known as Scopinaro procedure), and in one case, BADAS occurred in a patient with acute
164:
67:
584:
549:
454:
411:
375:
211:
137:
259:
complexes are thought to be caused by excessive exposure to bacterial antigens (especially
141:
113:
575:
Ely PH (June 1980). "The bowel bypass syndrome: a response to bacterial peptidoglycans".
260:
248:
152:
102:
588:
300:
610:
415:
231:
133:
125:
474:
431:
276:
267:
appears to be a frequent underlying condition. These antibodies possibly stimulate
188:
168:
117:
272:
219:
215:
156:
121:
553:
458:
379:
268:
129:
210:
can recur every 4–6 weeks and predominantly affect the upper chest and arms.
501:
466:
423:
179:
596:
561:
387:
256:
237:
203:
42:
252:
199:
106:
98:
191:
178:
94:
515:
Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007).
295:
183:
Crusts around the ankles and feet in the same patient as above
124:
have been used successfully to treat the condition (including
234:, but there is no erosion or deformation in the long term.
222:
is examined under the microscope, there can be signs of a
50:
Pustules and crusts around the elbows in a patient with
311:
66:
26:
21:
187:The most typical skin changes are a red patch (
147:BADAS has later been reported in patients with
35:Intestinal bypass arthritis–dermatitis syndrome
79:Bowel-associated dermatosis–arthritis syndrome
56:bowel-associated dermatosis-arthritis syndrome
22:Bowel-associated dermatosis–arthritis syndrome
361:
359:
357:
8:
230:of the fingers) and there can be associated
617:Reactive neutrophilic cutaneous conditions
159:). BADAS has also been reported following
41:
18:
155:and following resection of the stomach (
353:
7:
14:
416:10.1111/j.1468-3083.2004.00712.x
337:Sweet's syndrome-like dermatosis
299:
1:
589:10.1016/S0190-9622(80)80148-4
404:J Eur Acad Dermatol Venereol
342:List of cutaneous conditions
218:can affect the legs. When a
101:), multiple painful joints (
120:is thought to cause BADAS.
633:
554:10.1001/archinte.144.4.738
459:10.1381/096089204772787446
380:10.1001/archinte.143.3.457
149:inflammatory bowel disease
517:Dermatology: 2-Volume Set
161:biliopancreatic diversion
49:
40:
85:), is a complication of
224:neutrophilic dermatosis
308:This section is empty.
228:interphalangeal joints
184:
89:surgery consisting of
577:J. Am. Acad. Dermatol
182:
31:Bowel bypass syndrome
519:. St. Louis: Mosby.
265:Bacterial overgrowth
202:that heals without
208:maculopapular rash
185:
175:Symptoms and signs
87:jejunoileal bypass
542:Arch. Intern. Med
526:978-1-4160-2999-1
368:Arch. Intern. Med
328:
327:
194:) with a central
165:bariatric surgery
105:), muscle aches (
91:flu-like symptoms
76:
75:
16:Medical condition
624:
601:
600:
572:
566:
565:
537:
531:
530:
512:
506:
505:
485:
479:
478:
442:
436:
435:
398:
392:
391:
363:
323:
320:
310:You can help by
303:
296:
249:Immune complexes
240:may also occur.
212:Erythema nodosum
138:fluoroquinolones
45:
19:
632:
631:
627:
626:
625:
623:
622:
621:
607:
606:
605:
604:
574:
573:
569:
539:
538:
534:
527:
514:
513:
509:
496:(8): CS97–100.
490:Med. Sci. Monit
487:
486:
482:
444:
443:
439:
400:
399:
395:
365:
364:
355:
350:
333:
324:
318:
315:
294:
285:
246:
177:
142:Corticosteroids
114:immune response
52:Crohn's disease
17:
12:
11:
5:
630:
628:
620:
619:
609:
608:
603:
602:
567:
532:
525:
507:
480:
437:
393:
352:
351:
349:
346:
345:
344:
339:
332:
329:
326:
325:
306:
304:
293:
290:
284:
281:
261:peptidoglycans
245:
242:
176:
173:
153:diverticulitis
103:polyarthralgia
74:
73:
70:
64:
63:
47:
46:
38:
37:
28:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
629:
618:
615:
614:
612:
598:
594:
590:
586:
583:(6): 473–87.
582:
578:
571:
568:
563:
559:
555:
551:
548:(4): 738–40.
547:
543:
536:
533:
528:
522:
518:
511:
508:
503:
499:
495:
491:
484:
481:
476:
472:
468:
464:
460:
456:
452:
448:
441:
438:
433:
429:
425:
421:
417:
413:
409:
405:
397:
394:
389:
385:
381:
377:
374:(3): 457–61.
373:
369:
362:
360:
358:
354:
347:
343:
340:
338:
335:
334:
330:
322:
319:December 2023
313:
309:
305:
302:
298:
297:
291:
289:
282:
280:
278:
274:
270:
266:
262:
258:
254:
250:
243:
241:
239:
235:
233:
232:tenosynovitis
229:
225:
221:
217:
213:
209:
205:
201:
197:
193:
190:
181:
174:
172:
170:
166:
162:
158:
154:
150:
145:
143:
139:
135:
134:metronidazole
131:
127:
126:tetracyclines
123:
119:
115:
112:An excessive
110:
108:
104:
100:
96:
92:
88:
84:
80:
71:
69:
65:
61:
57:
53:
48:
44:
39:
36:
32:
29:
25:
20:
580:
576:
570:
545:
541:
535:
516:
510:
493:
489:
483:
453:(1): 133–5.
450:
446:
440:
410:(1): 89–92.
407:
403:
396:
371:
367:
316:
312:adding to it
307:
286:
277:pathogenesis
247:
236:
216:skin lesions
189:erythematous
186:
169:appendicitis
146:
118:gut bacteria
111:
82:
78:
77:
59:
55:
34:
30:
273:neutrophils
220:skin biopsy
163:(a form of
157:gastrectomy
122:Antibiotics
72:Dermatology
27:Other names
348:References
130:macrolides
447:Obes Surg
292:Treatment
283:Diagnosis
269:migration
244:Mechanism
68:Specialty
611:Category
502:17660731
475:24225355
467:14980049
432:32328280
424:14678541
331:See also
257:antibody
238:Diarrhea
204:scarring
597:7400404
562:6712372
388:6830382
253:antigen
206:. This
200:pustule
196:vesicle
107:myalgia
99:malaise
595:
560:
523:
500:
473:
465:
430:
422:
386:
214:-like
192:macula
471:S2CID
428:S2CID
95:fever
83:BADAS
60:BADAS
593:PMID
558:PMID
521:ISBN
498:PMID
463:PMID
420:PMID
384:PMID
136:and
54:and
33:and
585:doi
550:doi
546:144
455:doi
412:doi
376:doi
372:143
314:.
279:).
271:of
263:).
198:or
140:).
116:to
613::
591:.
579:.
556:.
544:.
494:13
492:.
469:.
461:.
451:14
449:.
426:.
418:.
408:18
406:.
382:.
370:.
356:^
151:,
132:,
128:,
97:,
599:.
587::
581:2
564:.
552::
529:.
504:.
477:.
457::
434:.
414::
390:.
378::
321:)
317:(
255:-
93:(
81:(
62:)
58:(
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.