1204:(Black Flying Fox) is described here. There were no significant amino acids that differed in c9orf135 from the rest of the mouse body. However, in the Black Flying Fox, it was valine poor and tryptophan rich. As seen from the human results, the Black Flying fox only shared the tryptophan surplus results. The House Mouse and Black Flying Fox were both used because they shared 64% and 79% similarity in the c9orf135 genome respectively. Analysis demonstrates that alanine and tyrosine could predict points of interest because they both contained results differing from the rest of the human gene averages.
234:
211:
1169:
1157:
108:
133:
1181:
240:
139:
935:
947:
879:
1890:
908:
923:
967:
It is likely that c9orf135 is a nuclear protein because it has properties that match attributes of nuclear proteins rather than secretory pathways. Furthermore, there is a nuclear localization signal (PEKVKKL) from amino acid 67 to 73 on c9orf135. C9orf135 is soluble with an average hydrophobicity of
1277:
The orthologs of c9orf135 were sequenced in BLAST and 20 orthologs were picked. The orthologs were all multicellular organisms and were limited to aquatic animals, reptiles, amphibians, and warm-blooded animals. Also, protists, bacteria, archea, and fungi did not have orthologs. However, no paralogs
1141:
c9orf135 is expressed in connective tissue and testicular tissue at high levels. It is likely that the expression of c9orf135 is expressed at low levels throughout human cells. It was also found that c9orf135 is found at significantly higher levels in the adult human umbilical cord versus the foetal
915:
The mRNA of c9orf135 is 906 nucleotides in length. The 5' and 3' Untranslated regions (UTR) contain hairpin loops. The 3' UTR comprises 123 nucleotides and the 5' UTR comprises 18 nucleotides. The mRNA encodes a protein with a secondary structure composed of both beta-sheets and alpha-helices.
1017:
Eleven different common DNA genome variants of the human c9orf135 gene have been identified. All of the mutations within those genome variants have been compiled into the following table. Mutations that were present at levels of 0.01 frequency or higher have been incorporated into the table;
1004:
stealing in which it binds the pre-mRNA cap an ultimately cleaves 10-13 nucleotides off. PB2 is also important for starting the replication of viral genomes. PB2 is also known to inhibit type 1 interferon by inhibiting the mitochondrial antiviral signalling protein
1278:
were found when c9orf135 was sequenced in BLAST. Please refer to the spreadsheet for the complete list of orthologs to c9orf135. Time tree was a program that was used to find the evolutionary branching shown in MYA There were no paralogs found for c9orf135.
2314:
886:
There is some evidence associating the c9orf135 gene with premature ovarian failure. In affected women, an autosomal recessive microduplication occurs which may be linked to premature ovarian failure. A
996:
PB2 interacts with c9orf135 which was found from a two-hybrid yeast assay. The information provided about PB2 (Polymerase Basic
Protein 2) is that it is a viral protein that is involved with the
2311:
2200:
247:
146:
1168:
2290:
2390:
2371:
540:
559:
69:
1006:
2041:"Genomic analysis using high-resolution single-nucleotide polymorphism arrays reveals novel microdeletions associated with premature ovarian failure"
1180:
1156:
2312:
https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?geneId=138255&ctg=NT_008470.20&mrna=XM_011518232.1&prot=XP_011516534.1&orien=forward
2091:
Chung SJ, Armasu SM, Biernacka JM, Anderson KJ, Lesnick TG, Rider DN, Cunningham JM, Eric
Ahlskog J, Frigerio R, Maraganore DM (August 2012).
1952:
1970:
2471:
233:
2143:
790:
783:
210:
1886:
is shown in the chart. Overall, c9orf135 has diverged significantly quicker than fibrinogen and slightly slower than cytochrome C.
934:
875:
superfamily 4572. Also, c9orf135 is known by the name of LOC138255 which is a description of the gene location on
Chromosome 9.1.
2333:
2162:
2197:
1939:
1918:
946:
2352:
888:
1935:
2181:
2023:
980:
sites were seen at amino acid positions 7, 50, 86, 98, and 194. Threonine phosphorylation occurs at 34, 129, 155, and 201.
132:
107:
1738:
1914:
2219:
1147:
246:
145:
2282:
1603:
872:
239:
138:
2387:
2368:
1765:
981:
604:
57:
1470:
1362:
585:
1711:
1143:
985:
922:
892:
1524:
871:
site at amino acid 75. C9orf135 is part of the GRCh37 gene on
Chromosome 9 and is contained within the
2266:
1019:
850:
121:
44:
2386:
Geo
Profile, Obese women with polycystic ovary syndrome and obese, healthy women: skeletal muscle,
1551:
745:
741:
737:
733:
686:
682:
678:
674:
988:
site is present at amino acid 3. A Signal cleavage site is present between amino acids 11 and 12.
1846:
1630:
1146:
the expression of c9orf135 is much higher in the epithelial cells within the ovaries. Women with
81:
766:
707:
2437:
2140:
2122:
2070:
1819:
1443:
997:
37:
899:. Further research is required to establish whether c9orf135 relates to Parkinson's disease.
2427:
2419:
2198:
http://abi.inf.uni-tuebingen.de/Services/YLoc/webloc.cgi?id=86ac5008fd25bd20a065f49a970fd19c
2112:
2104:
2060:
2052:
860:
326:
257:
201:
156:
77:
2394:
2375:
2356:
2337:
2318:
2270:
2223:
2204:
2185:
2166:
2147:
2027:
1792:
1416:
977:
301:
48:, chromosome 9 open reading frame 135, C9orf135, cilia and flagella associated protein 95
2476:
2432:
2407:
2367:
Geo
Profile, Ovarian normal surface epithelia and the ovarian cancer epithelial cells,
2117:
2092:
2065:
2040:
1001:
896:
878:
2330:
1150:
have a lower expression of c9orf135 than those people who do not have the condition.
2465:
2159:
2108:
2056:
868:
864:
2349:
968:-0.772. The negative hydrophobicity value is due to its slightly acidic properties.
61:
2457:
1889:
1879:
1389:
1335:
1308:
855:
319:
98:
85:
2020:
1988:
1975:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1957:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1684:
1657:
2178:
402:
2215:
SOSUI Classification and
Secondary Structure Prediction of Membrane Proteins,
1883:
1497:
846:
218:
115:
65:
2216:
2093:"Genomic determinants of motor and cognitive outcomes in Parkinson's disease"
1265:
c9orf135 is conserved through eukaryotes, ranging from mammals, reptiles and
2423:
2388:
https://www.ncbi.nlm.nih.gov/geo/tools/profileGraph.cgi?ID=GDS4133:243610_at
2369:
https://www.ncbi.nlm.nih.gov/geo/tools/profileGraph.cgi?ID=GDS3592:236519_at
2039:
McGuire MM, Bowden W, Engel NJ, Ahn HW, Kovanci E, Rajkovic A (April 2011).
907:
504:
462:
340:
285:
272:
184:
171:
73:
2441:
2126:
2074:
2235:
2006:
830:
825:
1266:
1124:
1107:
1090:
814:
649:
630:
616:
571:
2250:
798:
526:
1174:
Ovarian normal surface epithelia and ovarian cancer epithelial cells
1888:
1186:
Polycystic ovarian syndrome versus obese women regarding c9orf135.
906:
877:
2408:"Tree of life reveals clock-like speciation and diversification"
2406:
Hedges SB, Marin J, Suleski M, Paymer M, Kumar S (April 2015).
882:
c9orf135 location on chromosome 9 and the neighboring genes.
2141:
https://www.ncbi.nlm.nih.gov/nuccore/809279636?report=fasta
2019:
Result
Filters. (n.d.). Retrieved February 07, 2016, from
895:; a statistically significant mutation has been seen on a
2263:
1878:
A divergence comparison of c9orf135 with fast diverging
309:
2283:"1 binary interaction found for search term C9orf135"
474:
2331:
https://www.ncbi.nlm.nih.gov/nuccore/NM_001308086.1
759:
726:
700:
667:
2160:http://sfold.wadsworth.org/cgi-bin/showcentroid.pl
1931:
1929:
1927:
1910:
1908:
1906:
2350:https://www.ncbi.nlm.nih.gov/geoprofiles/78193260
1142:human umbilical cord. Furthermore, in women with
911:Splice Variants of c9orf135 based on NCBI AceView
256:
155:
1936:GRCm38: Ensembl release 89: ENSMUSG00000033053
984:sites occur at 78, 160, 177, and 209. Also, a
2021:https://www.ncbi.nlm.nih.gov/protein/Q5VTT2.1
8:
2179:http://zhanglab.ccmb.med.umich.edu/I-TASSER/
2086:
2084:
1915:GRCh38: Ensembl release 89: ENSG00000204711
891:(SNP) the c9orf135 gene has been linked to
2217:http://harrier.nagahama-i-bio.ac.jp/sosui/
500:
297:
196:
93:
2431:
2116:
2064:
1162:Fetal and Adult Umbilical cord expression
940:5' UTR loop structure of c9orf135 of mRNA
1280:
1206:
1024:
2236:http://psort.hgc.jp/cgi-bin/runpsort.pl
1902:
1196:A comparison between the c9orf135 from
1152:
918:
16:Mammalian protein found in Homo sapiens
2262:ExPasy, Sibs bioinformatics analysis,
2245:
2243:
1217:Compared to normal protein amounts in
952:3' UTR loop structure of c9orf135 mRNA
867:domain from amino acids 124-140 and a
18:
2287:IntAct Molecular Interaction Database
261:
222:
217:
160:
119:
114:
7:
2097:Parkinsonism & Related Disorders
2251:http://seqtool.sdsc.edu/CGI/BW.cgi#
2007:"BLAST protein sequence, c9orf135"
756:
723:
697:
664:
640:
621:
595:
576:
550:
531:
479:
397:
335:
314:
14:
2109:10.1016/j.parkreldis.2012.04.025
2057:10.1016/j.fertnstert.2010.12.052
1179:
1167:
1155:
972:Post-translational modifications
945:
933:
921:
245:
238:
232:
209:
144:
137:
131:
106:
2412:Molecular Biology and Evolution
2293:from the original on 2018-08-25
2234:PSORT II, PSORT II Prediction,
928:Secondary structure of c9orf135
2249:SDSC Biology Workbench, SAPS,
1000:. It is primarily involved in
889:Single Nucleotide Polymorphism
463:More reference expression data
359:olfactory zone of nasal mucosa
1:
1739:Strongylocentrotus purpuratus
845:is a gene that encodes a 229
445:vestibular sensory epithelium
230:
129:
1290:Divergence from Humans (MYA)
429:Epithelium of choroid plexus
2472:Genes on human chromosome 9
1148:polycystic ovarian syndrome
2493:
1604:Alligator mississippiensis
873:domain of unknown function
849:protein. It is located on
1971:"Mouse PubMed Reference:"
1953:"Human PubMed Reference:"
829:
824:
820:
813:
797:
778:
763:
730:
719:
704:
671:
660:
647:
643:
628:
624:
615:
602:
598:
583:
579:
570:
557:
553:
538:
534:
525:
510:
503:
499:
487:
482:
473:
460:
409:
400:
379:epithelium of nasopharynx
367:mucosa of paranasal sinus
351:bronchial epithelial cell
347:
338:
308:
300:
296:
279:
266:
229:
208:
199:
195:
178:
165:
128:
105:
96:
92:
55:
52:
42:
35:
30:
26:
21:
1766:Saccoglossus kowalevskii
1557:Chinese Softshell Turtle
1368:Golden Snub-Nosed Monkey
1213:Compositional Percentage
982:Tyrosine phosphorylation
791:Chr 19: 23.54 – 23.63 Mb
2045:Fertility and Sterility
1471:Panthera tigris altaica
1363:Rhinopithecus roxellana
784:Chr 9: 69.82 – 69.91 Mb
2264:http://www.expasy.org/
1893:
1874:Divergence of c9orf135
1712:Branchiostoma floridae
1210:Amino Acid of Interest
1144:ovarian adenocarcinoma
986:N-terminal acetylation
963:Properties of c9orf135
912:
883:
2424:10.1093/molbev/msv037
1892:
1882:, and slow diverging
1525:Elephantulus edwardii
910:
881:
224:Chromosome 19 (mouse)
1302:Sequence similarity
1020:synonymous mutations
863:. The protein has a
425:olfactory epithelium
122:Chromosome 9 (human)
2329:EST profile, NCBI,
1552:Pelodiscus sinensis
1530:Cape Elephant Shrew
1192:Amino Acid Quantity
1031:Amino Acid Position
992:Protein Interaction
893:Parkinson's disease
413:seminiferous tubule
2393:2018-08-19 at the
2374:2018-08-19 at the
2355:2016-09-15 at the
2348:Geo Profile, NCBI
2336:2016-09-16 at the
2317:2018-06-23 at the
2310:NCBI SNP Geneview
2269:2018-01-30 at the
2222:2016-05-05 at the
2203:2016-06-03 at the
2184:2020-02-24 at the
2165:2016-05-06 at the
2146:2016-09-15 at the
2139:NCBI, Nucleotide,
2026:2018-06-23 at the
1894:
1847:Helobdella robusta
1631:Ophiophagus hannah
1609:American Alligator
1449:Przewalski's horse
1341:Sumatran Orangutan
1254:More than average
1243:More than Average
1232:Less than Average
1200:(House Mouse) and
913:
884:
605:ENSMUSG00000033053
371:right uterine tube
86:CFAP95 - orthologs
1871:
1870:
1820:Crassostrea gigas
1444:Equus przewalskii
1299:Sequence identity
1296:Amino Acid Length
1258:
1257:
1134:
1133:
998:influenza A virus
840:
839:
836:
835:
809:
808:
774:
773:
753:
752:
715:
714:
694:
693:
656:
655:
637:
636:
611:
610:
592:
591:
566:
565:
547:
546:
495:
494:
491:
490:
469:
468:
456:
455:
394:
393:
292:
291:
191:
190:
2484:
2446:
2445:
2435:
2403:
2397:
2384:
2378:
2365:
2359:
2346:
2340:
2327:
2321:
2308:
2302:
2301:
2299:
2298:
2279:
2273:
2260:
2254:
2247:
2238:
2232:
2226:
2213:
2207:
2194:
2188:
2175:
2169:
2156:
2150:
2137:
2131:
2130:
2120:
2088:
2079:
2078:
2068:
2036:
2030:
2017:
2011:
2010:
2003:
1997:
1996:
1985:
1979:
1978:
1967:
1961:
1960:
1949:
1943:
1933:
1922:
1912:
1422:Black Flying Fox
1293:Accession number
1281:
1207:
1183:
1171:
1159:
1025:
949:
937:
925:
822:
821:
793:
786:
769:
757:
748:
724:
720:RefSeq (protein)
710:
698:
689:
665:
641:
622:
596:
577:
551:
532:
501:
480:
465:
405:
403:Top expressed in
398:
375:nasal epithelium
343:
341:Top expressed in
336:
315:
298:
288:
275:
264:
249:
242:
236:
225:
213:
197:
187:
174:
163:
148:
141:
135:
124:
110:
94:
88:
47:
40:
19:
2492:
2491:
2487:
2486:
2485:
2483:
2482:
2481:
2462:
2461:
2455:
2453:Further reading
2450:
2449:
2405:
2404:
2400:
2395:Wayback Machine
2385:
2381:
2376:Wayback Machine
2366:
2362:
2357:Wayback Machine
2347:
2343:
2338:Wayback Machine
2328:
2324:
2319:Wayback Machine
2309:
2305:
2296:
2294:
2281:
2280:
2276:
2271:Wayback Machine
2261:
2257:
2248:
2241:
2233:
2229:
2224:Wayback Machine
2214:
2210:
2205:Wayback Machine
2195:
2191:
2186:Wayback Machine
2176:
2172:
2167:Wayback Machine
2157:
2153:
2148:Wayback Machine
2138:
2134:
2090:
2089:
2082:
2051:(5): 1595–600.
2038:
2037:
2033:
2028:Wayback Machine
2018:
2014:
2005:
2004:
2000:
1987:
1986:
1982:
1969:
1968:
1964:
1951:
1950:
1946:
1934:
1925:
1913:
1904:
1899:
1876:
1793:Lingula anatina
1663:Atlantic Salmon
1578:Gekko japonicus
1417:Pteropus alecto
1275:
1263:
1202:Pteropus alecto
1194:
1187:
1184:
1175:
1172:
1163:
1160:
1139:
1137:Gene Expression
1022:were excluded.
1015:
994:
978:phosphorylation
974:
965:
960:
953:
950:
941:
938:
929:
926:
905:
831:View/Edit Mouse
826:View/Edit Human
789:
782:
779:Location (UCSC)
765:
744:
740:
736:
732:
706:
685:
681:
677:
673:
586:ENSG00000204711
461:
452:
449:right lung lobe
447:
443:
439:
435:
431:
427:
423:
419:
415:
401:
390:
385:
383:pituitary gland
381:
377:
373:
369:
365:
361:
357:
353:
339:
283:
270:
262:
252:
251:
250:
243:
223:
200:Gene location (
182:
169:
161:
151:
150:
149:
142:
120:
97:Gene location (
56:
43:
36:
17:
12:
11:
5:
2490:
2488:
2480:
2479:
2474:
2464:
2463:
2454:
2451:
2448:
2447:
2398:
2379:
2360:
2341:
2322:
2303:
2274:
2255:
2239:
2227:
2208:
2189:
2170:
2151:
2132:
2080:
2031:
2012:
1998:
1980:
1962:
1944:
1923:
1901:
1900:
1898:
1895:
1875:
1872:
1869:
1868:
1865:
1862:
1859:
1856:
1853:
1850:
1842:
1841:
1838:
1835:
1832:
1829:
1826:
1825:Pacific Oyster
1823:
1815:
1814:
1811:
1808:
1805:
1802:
1799:
1796:
1788:
1787:
1784:
1781:
1778:
1775:
1772:
1769:
1761:
1760:
1757:
1754:
1751:
1748:
1745:
1742:
1734:
1733:
1730:
1727:
1724:
1721:
1718:
1715:
1707:
1706:
1703:
1700:
1697:
1694:
1691:
1688:
1680:
1679:
1676:
1673:
1670:
1667:
1664:
1661:
1653:
1652:
1649:
1646:
1643:
1640:
1637:
1634:
1626:
1625:
1622:
1619:
1616:
1613:
1610:
1607:
1599:
1598:
1595:
1592:
1589:
1586:
1583:
1580:
1574:
1573:
1570:
1567:
1564:
1561:
1558:
1555:
1547:
1546:
1543:
1540:
1537:
1534:
1531:
1528:
1520:
1519:
1516:
1513:
1510:
1507:
1504:
1501:
1493:
1492:
1489:
1486:
1483:
1480:
1477:
1476:Siberian Tiger
1474:
1466:
1465:
1462:
1459:
1456:
1453:
1450:
1447:
1439:
1438:
1435:
1432:
1429:
1426:
1423:
1420:
1412:
1411:
1408:
1405:
1402:
1399:
1396:
1393:
1385:
1384:
1381:
1378:
1375:
1372:
1369:
1366:
1358:
1357:
1354:
1351:
1348:
1345:
1342:
1339:
1331:
1330:
1327:
1324:
1321:
1318:
1315:
1312:
1304:
1303:
1300:
1297:
1294:
1291:
1288:
1285:
1274:
1271:
1262:
1259:
1256:
1255:
1252:
1249:
1245:
1244:
1241:
1238:
1234:
1233:
1230:
1227:
1223:
1222:
1214:
1211:
1193:
1190:
1189:
1188:
1185:
1178:
1176:
1173:
1166:
1164:
1161:
1154:
1138:
1135:
1132:
1131:
1128:
1122:
1119:
1115:
1114:
1111:
1105:
1102:
1098:
1097:
1094:
1088:
1085:
1081:
1080:
1077:
1074:
1071:
1067:
1066:
1063:
1060:
1057:
1053:
1052:
1049:
1046:
1043:
1039:
1038:
1035:
1032:
1029:
1014:
1011:
993:
990:
973:
970:
964:
961:
959:
956:
955:
954:
951:
944:
942:
939:
932:
930:
927:
920:
904:
901:
897:Manhattan plot
838:
837:
834:
833:
828:
818:
817:
811:
810:
807:
806:
804:
802:
795:
794:
787:
780:
776:
775:
772:
771:
761:
760:
754:
751:
750:
728:
727:
721:
717:
716:
713:
712:
702:
701:
695:
692:
691:
669:
668:
662:
658:
657:
654:
653:
645:
644:
638:
635:
634:
626:
625:
619:
613:
612:
609:
608:
600:
599:
593:
590:
589:
581:
580:
574:
568:
567:
564:
563:
555:
554:
548:
545:
544:
536:
535:
529:
523:
522:
517:
512:
508:
507:
497:
496:
493:
492:
489:
488:
485:
484:
477:
471:
470:
467:
466:
458:
457:
454:
453:
451:
450:
446:
442:
438:
434:
430:
426:
422:
418:
414:
410:
407:
406:
395:
392:
391:
389:
388:
384:
380:
376:
372:
368:
364:
360:
356:
352:
348:
345:
344:
332:
331:
323:
312:
306:
305:
302:RNA expression
294:
293:
290:
289:
281:
277:
276:
268:
265:
260:
254:
253:
244:
237:
231:
227:
226:
221:
215:
214:
206:
205:
193:
192:
189:
188:
180:
176:
175:
167:
164:
159:
153:
152:
143:
136:
130:
126:
125:
118:
112:
111:
103:
102:
90:
89:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
2489:
2478:
2475:
2473:
2470:
2469:
2467:
2460:
2459:
2452:
2443:
2439:
2434:
2429:
2425:
2421:
2418:(4): 835–45.
2417:
2413:
2409:
2402:
2399:
2396:
2392:
2389:
2383:
2380:
2377:
2373:
2370:
2364:
2361:
2358:
2354:
2351:
2345:
2342:
2339:
2335:
2332:
2326:
2323:
2320:
2316:
2313:
2307:
2304:
2292:
2288:
2284:
2278:
2275:
2272:
2268:
2265:
2259:
2256:
2252:
2246:
2244:
2240:
2237:
2231:
2228:
2225:
2221:
2218:
2212:
2209:
2206:
2202:
2199:
2193:
2190:
2187:
2183:
2180:
2174:
2171:
2168:
2164:
2161:
2158:Sfold, Srna,
2155:
2152:
2149:
2145:
2142:
2136:
2133:
2128:
2124:
2119:
2114:
2110:
2106:
2102:
2098:
2094:
2087:
2085:
2081:
2076:
2072:
2067:
2062:
2058:
2054:
2050:
2046:
2042:
2035:
2032:
2029:
2025:
2022:
2016:
2013:
2008:
2002:
1999:
1994:
1993:NCBI, Protein
1990:
1984:
1981:
1976:
1972:
1966:
1963:
1958:
1954:
1948:
1945:
1941:
1937:
1932:
1930:
1928:
1924:
1920:
1916:
1911:
1909:
1907:
1903:
1896:
1891:
1887:
1885:
1881:
1873:
1866:
1863:
1860:
1857:
1854:
1851:
1849:
1848:
1844:
1843:
1839:
1836:
1833:
1830:
1827:
1824:
1822:
1821:
1817:
1816:
1812:
1809:
1806:
1803:
1800:
1797:
1795:
1794:
1790:
1789:
1785:
1782:
1779:
1776:
1773:
1770:
1768:
1767:
1763:
1762:
1758:
1755:
1752:
1749:
1746:
1743:
1741:
1740:
1736:
1735:
1731:
1728:
1725:
1722:
1719:
1716:
1714:
1713:
1709:
1708:
1704:
1701:
1698:
1695:
1692:
1690:Northern Pike
1689:
1687:
1686:
1682:
1681:
1677:
1674:
1671:
1668:
1665:
1662:
1660:
1659:
1655:
1654:
1650:
1647:
1644:
1641:
1638:
1635:
1633:
1632:
1628:
1627:
1623:
1620:
1617:
1614:
1611:
1608:
1606:
1605:
1601:
1600:
1596:
1593:
1590:
1587:
1584:
1581:
1579:
1576:
1575:
1571:
1568:
1565:
1562:
1559:
1556:
1554:
1553:
1549:
1548:
1544:
1541:
1538:
1535:
1532:
1529:
1527:
1526:
1522:
1521:
1517:
1514:
1511:
1508:
1505:
1502:
1500:
1499:
1495:
1494:
1490:
1487:
1484:
1481:
1478:
1475:
1473:
1472:
1468:
1467:
1463:
1460:
1457:
1454:
1451:
1448:
1446:
1445:
1441:
1440:
1436:
1433:
1430:
1427:
1424:
1421:
1419:
1418:
1414:
1413:
1409:
1406:
1403:
1400:
1397:
1394:
1392:
1391:
1387:
1386:
1382:
1379:
1376:
1373:
1370:
1367:
1365:
1364:
1360:
1359:
1355:
1352:
1349:
1346:
1343:
1340:
1338:
1337:
1333:
1332:
1328:
1325:
1322:
1319:
1316:
1313:
1311:
1310:
1306:
1305:
1301:
1298:
1295:
1292:
1289:
1286:
1284:Genus/Species
1283:
1282:
1279:
1272:
1270:
1268:
1260:
1253:
1250:
1247:
1246:
1242:
1239:
1236:
1235:
1231:
1228:
1225:
1224:
1221:
1220:
1215:
1212:
1209:
1208:
1205:
1203:
1199:
1191:
1182:
1177:
1170:
1165:
1158:
1153:
1151:
1149:
1145:
1136:
1129:
1126:
1123:
1120:
1117:
1116:
1112:
1109:
1106:
1103:
1100:
1099:
1095:
1092:
1089:
1086:
1083:
1082:
1078:
1075:
1072:
1069:
1068:
1064:
1061:
1058:
1055:
1054:
1050:
1047:
1044:
1041:
1040:
1036:
1033:
1030:
1027:
1026:
1023:
1021:
1012:
1010:
1008:
1003:
999:
991:
989:
987:
983:
979:
971:
969:
962:
957:
948:
943:
936:
931:
924:
919:
917:
909:
902:
900:
898:
894:
890:
880:
876:
874:
870:
869:glycosylation
866:
865:transmembrane
862:
858:
857:
852:
848:
844:
832:
827:
823:
819:
816:
812:
805:
803:
800:
796:
792:
788:
785:
781:
777:
770:
768:
762:
758:
755:
749:
747:
743:
739:
735:
729:
725:
722:
718:
711:
709:
703:
699:
696:
690:
688:
684:
680:
676:
670:
666:
663:
661:RefSeq (mRNA)
659:
652:
651:
646:
642:
639:
633:
632:
627:
623:
620:
618:
614:
607:
606:
601:
597:
594:
588:
587:
582:
578:
575:
573:
569:
562:
561:
556:
552:
549:
543:
542:
537:
533:
530:
528:
524:
521:
518:
516:
513:
509:
506:
502:
498:
486:
481:
478:
476:
472:
464:
459:
448:
444:
440:
436:
432:
428:
424:
420:
416:
412:
411:
408:
404:
399:
396:
386:
382:
378:
374:
370:
366:
362:
358:
354:
350:
349:
346:
342:
337:
334:
333:
330:
328:
324:
322:
321:
317:
316:
313:
311:
307:
303:
299:
295:
287:
282:
278:
274:
269:
259:
255:
248:
241:
235:
228:
220:
216:
212:
207:
203:
198:
194:
186:
181:
177:
173:
168:
158:
154:
147:
140:
134:
127:
123:
117:
113:
109:
104:
100:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
2458:Chromosome 9
2456:
2415:
2411:
2401:
2382:
2363:
2344:
2325:
2306:
2295:. Retrieved
2289:. EMBL-EBI.
2286:
2277:
2258:
2230:
2211:
2192:
2173:
2154:
2135:
2103:(7): 881–6.
2100:
2096:
2048:
2044:
2034:
2015:
2001:
1992:
1983:
1974:
1965:
1956:
1947:
1880:cytochrome C
1877:
1858:XP_009019861
1845:
1831:XP_011426944
1818:
1804:XP_013398605
1791:
1777:XP_002733410
1764:
1737:
1723:XP_002591786
1710:
1696:XP_010901691
1683:
1669:XP_013998840
1656:
1629:
1615:XP_014464144
1602:
1588:XP_015275999
1577:
1563:XP_006137902
1550:
1536:XP_006894485
1523:
1509:XP_014948670
1496:
1482:XP_007077537
1469:
1455:XP_008504806
1442:
1415:
1390:Mus musculus
1388:
1374:XP_010361250
1361:
1347:XP_002819904
1336:Pongo abelii
1334:
1309:Homo sapiens
1307:
1276:
1264:
1218:
1216:
1201:
1198:Mus musculus
1197:
1195:
1140:
1016:
995:
975:
966:
914:
885:
856:Homo sapiens
854:
851:Chromosome 9
842:
841:
764:
746:NP_001295015
742:NP_001295014
738:NP_001295013
734:NP_001010940
731:
705:
687:NM_001308086
683:NM_001308085
679:NM_001308084
675:NM_001010940
672:
648:
629:
603:
584:
558:
539:
519:
514:
421:spermatocyte
325:
318:
263:19|19 B
53:External IDs
1685:Esox lucius
1658:Salmo salar
1395:House Mouse
1287:Common name
284:23,630,176
271:23,536,117
183:69,906,227
170:69,820,817
31:Identifiers
2466:Categories
2297:2018-08-25
2177:I-Tasser,
1989:"Q5VTT2.1"
1942:, May 2017
1921:, May 2017
1897:References
1884:fibrinogen
1798:Ocean Clam
1771:Acorn Worm
1744:Sea Urchin
1636:King Cobra
1498:Ovis aries
1219:H. sapiens
1037:Frequency
859:genome at
847:amino acid
329:(ortholog)
66:HomoloGene
1750:XP_785964
1428:XP_785964
1273:Orthologs
1248:Trytophan
1013:Mutations
767:NP_080464
708:NM_026188
505:Orthologs
417:spermatid
74:GeneCards
2442:25739733
2391:Archived
2372:Archived
2353:Archived
2334:Archived
2315:Archived
2291:Archived
2267:Archived
2220:Archived
2201:Archived
2182:Archived
2163:Archived
2144:Archived
2127:22658654
2075:21256485
2024:Archived
1938:–
1917:–
1717:Lancelet
1642:ETE61720
1401:EDL41604
1267:Annelida
1261:Homology
1237:Tyrosine
1125:Missense
1108:Missense
1091:Missense
1034:Mutation
1028:Location
843:C9orf135
815:Wikidata
355:testicle
2433:4379413
2118:3606821
2066:3062633
1940:Ensembl
1919:Ensembl
1226:Alanine
976:Serine
958:Protein
861:9q12.21
853:of the
617:UniProt
572:Ensembl
511:Species
441:utricle
387:trachea
304:pattern
162:9q21.12
62:1914733
38:Aliases
2440:
2430:
2125:
2115:
2073:
2063:
1320:Q5VTT2
1113:0.047
1096:0.018
1079:0.018
1070:5' UTR
1065:0.047
1056:5' UTR
1051:0.386
1042:5' UTR
801:search
799:PubMed
650:Q9CQC3
631:Q5VTT2
541:138255
527:Entrez
475:BioGPS
437:embryo
433:morula
78:CFAP95
45:CFAP95
22:CFAP95
2477:Genes
2196:YLoc
1852:Leech
1774:747.8
1747:747.8
1693:429.6
1666:429.6
1639:320.5
1612:320.5
1585:320.5
1582:Gekko
1560:320.5
1503:Sheep
1314:Human
1130:0.01
1127:E126K
560:67483
520:Mouse
515:Human
363:sperm
327:Mouse
320:Human
267:Start
202:Mouse
166:Start
99:Human
70:49850
2438:PMID
2123:PMID
2071:PMID
1867:44%
1840:57%
1813:59%
1786:58%
1759:62%
1732:59%
1705:47%
1678:55%
1651:59%
1624:64%
1597:64%
1572:68%
1545:82%
1518:77%
1506:97.5
1491:83%
1479:97.5
1464:86%
1452:97.5
1437:86%
1425:97.5
1410:73%
1398:90.9
1383:95%
1371:29.1
1356:87%
1344:15.8
1251:3.1%
1240:5.2%
1229:3.1%
1118:Exon
1110:R53K
1101:Exon
1093:K30T
1084:Exon
1007:MAVS
903:mRNA
310:Bgee
258:Band
219:Chr.
157:Band
116:Chr.
2428:PMC
2420:doi
2113:PMC
2105:doi
2061:PMC
2053:doi
1864:29%
1861:256
1855:847
1837:40%
1834:215
1828:847
1810:43%
1807:220
1801:847
1783:38%
1780:153
1756:47%
1753:241
1729:45%
1726:221
1720:733
1702:30%
1699:154
1675:34%
1648:43%
1645:215
1621:51%
1618:212
1594:52%
1591:221
1569:55%
1566:217
1542:72%
1539:254
1533:105
1515:69%
1512:207
1488:73%
1485:187
1461:77%
1458:183
1434:79%
1431:230
1407:64%
1404:228
1380:93%
1377:229
1353:86%
1350:206
1329:--
1323:229
1121:456
1104:237
1087:169
1076:N/A
1073:138
1062:N/A
1048:N/A
1002:Cap
483:n/a
280:End
179:End
82:OMA
58:MGI
2468::
2436:.
2426:.
2416:32
2414:.
2410:.
2285:.
2242:^
2121:.
2111:.
2101:18
2099:.
2095:.
2083:^
2069:.
2059:.
2049:95
2047:.
2043:.
1991:.
1973:.
1955:.
1926:^
1905:^
1672:99
1326:--
1317:--
1269:.
1059:93
1045:57
1009:.
286:bp
273:bp
185:bp
172:bp
80:;
76::
72:;
68::
64:;
60::
2444:.
2422::
2300:.
2253:!
2129:.
2107::
2077:.
2055::
2009:.
1995:.
1977:.
1959:.
204:)
101:)
84::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
