40:
276:. Comparative studies involving cytochrome b have resulted in new classification schemes and have been used to assign newly described species to a genus as well as to deepen the understanding of evolutionary relationships.
252:
The heme groups are key parts of the internal electron transfer pathway and indispensable to the functioning of the two quinol oxidizing complexes. Two units of b/b6 also form a quinol entry pathway.
701:
1594:
122:
702:"FRAC Code List ©*2021: Fungal control agents sorted by cross resistance pattern and mode of action (including coding for FRAC Groups on product labels)"
471:
416:
Howell N (August 1989). "Evolutionary conservation of protein regions in the proton motive cytochrome b and their possible roles in redox catalysis".
913:
697:
354:
191:
268:
relationships between organisms, due to its sequence variability. It is considered to be most useful in determining relationships within
1614:
754:
827:
708:
512:
Sarewicz, M; Pintscher, S; Pietras, R; Borek, A; Bujnowicz, Ł; Hanke, G; Cramer, WA; Finazzi, G; Osyczka, A (24 February 2021).
1629:
142:
514:"Catalytic Reactions and Energy Conservation in the Cytochrome bc(1) and b(6)f Complexes of Energy-Transducing Membranes"
608:
Blakely EL, Mitchell AL, Fisher N, Meunier B, Nijtmans LG, Schaefer AM, Jackson MJ, Turnbull DM, Taylor RW (July 2005).
906:
1624:
745:
374:
1619:
981:
885:
202:
195:
176:
610:"A mitochondrial cytochrome b mutation causing severe respiratory chain enzyme deficiency in humans and yeast"
130:
1059:
1040:
1003:
818:
214:
45:
899:
657:
Siregar JE, Syafruddin D, Matsuoka H, Kita K, Marzuki S (June 2008). "Mutation underlying resistance of
234:
737:"Grey mould of strawberry, a devastating disease caused by the ubiquitous necrotrophic fungal pathogen
126:
808:
Cosseboom, Scott D.; Ivors, Kelly L.; Schnabel, Guido; Bryson, Patricia K.; Holmes, Gerald J. (2019).
1184:
1170:
1156:
1142:
425:
285:
1450:
1420:
1344:
986:
206:
1434:
1116:
857:
796:
639:
449:
230:
1415:
1310:
849:
841:
788:
770:
678:
631:
590:
545:
494:
441:
288:
in human patients; though more rare, severe multi-system pathologies have also been reported.
261:
169:
117:
327:
1320:
1279:
1209:
891:
831:
778:
762:
735:
Petrasch, Stefan; Knapp, Steven J.; van Kan, Jan A. L.; Blanco-Ulate, Barbara (2019-04-04).
670:
621:
580:
535:
525:
486:
433:
269:
226:
369:
provide resistance against the main body of group 11, although G143A does not work against
245:
groups, known as b562 and b566. Four conserved histidine residues are postulated to be the
109:
1574:
1429:
758:
585:
564:
370:
238:
210:
881:
429:
1476:
1471:
783:
736:
540:
513:
1608:
1581:
1540:
1455:
1262:
1044:
1027:
966:
861:
626:
609:
490:
187:
161:
800:
643:
71:
1510:
1386:
1372:
1358:
1248:
1223:
453:
265:
183:
105:
674:
661:
to atovaquone in the quinone binding domain 2 (Qo(2)) of the cytochrome b gene".
83:
1517:
930:
530:
182:) — also known as the bc1 complex or ubiquinol-cytochrome c reductase. In plant
172:
165:
836:
809:
1564:
1522:
1425:
948:
470:
Esposti MD, De Vries S, Crimi M, Ghelli A, Patarnello T, Meyer A (July 1993).
300:
845:
774:
241:
encoded by the petB and petD genes. Cytochrome b/b6 non-covalently binds two
1505:
158:
17:
853:
792:
682:
635:
594:
549:
498:
445:
198:
78:
179:
922:
437:
246:
766:
939:
333:
137:
472:"Mitochondrial cytochrome b: evolution and structure of the protein"
39:
190:, there is a homologous protein, cytochrome b6, a component of the
991:
321:
315:
273:
201:), also known as the b6f complex. These complexes are involved in
1100:
1088:
1083:
1015:
926:
242:
99:
66:
895:
1330:
1071:
346:
237:. In plants and cyanobacteria, cytochrome b6 consists of two
205:, the pumping of protons to create a proton-motive force (
810:"Within-Season Shift in Fungicide Resistance Profiles of
299:
are associated with resistance to the anti-malarial drug
157:
is a protein found in the membranes of aerobic cells. In
27:
Membrane protein involved in the electron transport chain
569:
Phylogeny and the
Taxonomy of Great Apes and Mammals"
324:– cytochrome b5 type B (outer mitochondrial membrane)
311:
Human genes encoding cytochrome b proteins include:
1557:
1531:
1496:
1489:
1464:
1443:
1408:
1301:
1241:
1202:
1135:
1124:
1115:
1038:
963:
956:
947:
938:
136:
116:
98:
93:
77:
65:
57:
52:
32:
284:Mutations in cytochrome b primarily result in
217:. These complexes play a vital role in cells.
907:
465:
463:
411:
409:
260:Cytochrome b is commonly used as a region of
249:of the iron atoms of these two heme groups.
8:
1493:
1132:
1121:
960:
953:
944:
914:
900:
892:
291:Single-point mutations in cytochrome b of
90:
1595:disorders of globin and globulin proteins
884:at the U.S. National Library of Medicine
835:
782:
625:
584:
539:
529:
402:. Blackwell Publishing. pp. 124–132.
390:
400:Molecular Mechanisms of Photosynthesis
336:– mitochondrially encoded cytochrome b
29:
698:Fungicide Resistance Action Committee
586:10.1093/oxfordjournals.molbev.a003825
355:Fungicide Resistance Action Committee
330:– cytochrome b, ascorbate dependent 3
7:
192:plastoquinone-plastocyanin reductase
755:British Society for Plant Pathology
379:in California strawberry production
318:– cytochrome b5 type A (microsomal)
828:American Phytopathological Society
25:
168:, cytochrome b is a component of
814:in California Strawberry Fields"
627:10.1111/j.1742-4658.2005.04779.x
164:(inner membrane) and in aerobic
38:
573:Molecular Biology and Evolution
225:Cytochrome b/b6 is an integral
33:Cytochrome b, C-terminal domain
357:group 11. The cyt b mutations
213:is used for the generation of
1:
94:Available protein structures:
675:10.1016/j.parint.2007.12.002
491:10.1016/0005-2728(93)90197-N
398:Blankenship, Robert (2009).
373:(11A). G143A is significant
531:10.1021/acs.chemrev.0c00712
1646:
1615:Electron-transfer proteins
837:10.1094/pdis-03-18-0406-re
663:Parasitology International
1590:
746:Molecular Plant Pathology
345:Cyt b is targeted by the
89:
37:
886:Medical Subject Headings
563:Castresana, J. (2001).
1630:Transmembrane proteins
479:Biochim. Biophys. Acta
235:transmembrane segments
221:Structure and function
46:cytochrome bc1 complex
353:class of fungicides,
293:Plasmodium falciparum
280:Clinical significance
229:of approximately 400
286:exercise intolerance
256:Use in phylogenetics
233:that probably has 8
1451:Glycated hemoglobin
1421:Carbaminohemoglobin
430:1989JMolE..29..157H
231:amino acid residues
659:Plasmodium berghei
438:10.1007/BF02100114
203:electron transport
1602:
1601:
1553:
1552:
1549:
1548:
1485:
1484:
1416:Carboxyhemoglobin
1404:
1403:
1297:
1296:
1111:
1110:
767:10.1111/mpp.12794
262:mitochondrial DNA
170:respiratory chain
152:
151:
148:
147:
143:structure summary
16:(Redirected from
1637:
1625:Protein families
1494:
1133:
1122:
961:
954:
945:
916:
909:
902:
893:
869:
865:
839:
812:Botrytis cinerea
804:
786:
739:Botrytis cinerea
729:
723:
722:
720:
719:
713:
707:. Archived from
706:
700:) (March 2021).
693:
687:
686:
654:
648:
647:
629:
605:
599:
598:
588:
560:
554:
553:
543:
533:
524:(4): 2020–2108.
518:Chemical Reviews
509:
503:
502:
476:
467:
458:
457:
413:
404:
403:
395:
377:Botrytis cinerea
368:
367:
362:
361:
341:Fungicide target
264:for determining
239:protein subunits
227:membrane protein
91:
42:
30:
21:
1645:
1644:
1640:
1639:
1638:
1636:
1635:
1634:
1620:Protein domains
1605:
1604:
1603:
1598:
1586:
1575:Cytochrome P450
1545:
1527:
1481:
1460:
1439:
1430:Deoxyhemoglobin
1400:
1396:
1392:
1382:
1378:
1368:
1364:
1354:
1350:
1340:
1336:
1326:
1316:
1293:
1289:
1285:
1275:
1271:
1266:
1258:
1254:
1237:
1233:
1229:
1219:
1215:
1198:
1194:
1190:
1185:HbE Portland II
1180:
1176:
1166:
1162:
1152:
1148:
1127:
1107:
1034:
965:Alpha locus on
934:
920:
878:
873:
872:
868:
807:
734:
730:
726:
717:
715:
711:
704:
695:
694:
690:
656:
655:
651:
620:(14): 3583–92.
607:
606:
602:
562:
561:
557:
511:
510:
506:
474:
469:
468:
461:
415:
414:
407:
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396:
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387:
371:metyltetraprole
365:
364:
359:
358:
350:
343:
309:
282:
258:
223:
211:proton gradient
48:
28:
23:
22:
15:
12:
11:
5:
1643:
1641:
1633:
1632:
1627:
1622:
1617:
1607:
1606:
1600:
1599:
1591:
1588:
1587:
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1584:
1579:
1578:
1577:
1572:
1561:
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1555:
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1551:
1550:
1547:
1546:
1544:
1543:
1537:
1535:
1529:
1528:
1526:
1525:
1520:
1515:
1514:
1513:
1502:
1500:
1491:
1487:
1486:
1483:
1482:
1480:
1479:
1477:Erythrocruorin
1474:
1468:
1466:
1462:
1461:
1459:
1458:
1453:
1447:
1445:
1441:
1440:
1438:
1437:
1435:Sulfhemoglobin
1432:
1423:
1418:
1412:
1410:
1406:
1405:
1402:
1401:
1399:
1398:
1394:
1390:
1384:
1380:
1376:
1370:
1366:
1362:
1356:
1352:
1348:
1342:
1338:
1334:
1328:
1324:
1318:
1314:
1307:
1305:
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1298:
1295:
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1283:
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1273:
1269:
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1260:
1256:
1252:
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1239:
1238:
1236:
1235:
1231:
1227:
1221:
1217:
1213:
1206:
1204:
1200:
1199:
1197:
1196:
1192:
1188:
1182:
1178:
1174:
1171:HbE Portland I
1168:
1164:
1160:
1154:
1150:
1146:
1139:
1137:
1130:
1119:
1113:
1112:
1109:
1108:
1106:
1105:
1104:
1103:
1093:
1092:
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1086:
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1007:
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989:
984:
973:
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904:
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876:External links
874:
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579:(4): 465–471.
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44:Mitochondrial
43:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
1642:
1631:
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1626:
1623:
1621:
1618:
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1613:
1612:
1610:
1597:
1596:
1589:
1583:
1582:Methemalbumin
1580:
1576:
1573:
1571:
1568:
1567:
1566:
1563:
1562:
1560:
1556:
1542:
1541:Leghemoglobin
1539:
1538:
1536:
1534:
1530:
1524:
1521:
1519:
1516:
1512:
1509:
1508:
1507:
1504:
1503:
1501:
1499:
1495:
1492:
1488:
1478:
1475:
1473:
1472:Chlorocruorin
1470:
1469:
1467:
1463:
1457:
1456:Methemoglobin
1454:
1452:
1449:
1448:
1446:
1442:
1436:
1433:
1431:
1427:
1426:Oxyhemoglobin
1424:
1422:
1419:
1417:
1414:
1413:
1411:
1407:
1388:
1385:
1374:
1371:
1360:
1357:
1346:
1343:
1332:
1329:
1322:
1319:
1312:
1309:
1308:
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1304:
1300:
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1267:
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1211:
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1201:
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1172:
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1131:
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1082:
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1080:
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1029:
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1021:
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1001:
1000:
997:
993:
990:
988:
985:
983:
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979:
978:
975:
974:
972:
970:
968:
962:
959:
955:
952:
950:
946:
943:
941:
937:
932:
928:
925:that contain
924:
917:
912:
910:
905:
903:
898:
897:
894:
887:
883:
882:Cytochromes+b
880:
879:
875:
863:
859:
855:
851:
847:
843:
838:
833:
829:
825:
821:
820:
819:Plant Disease
815:
813:
806:
802:
798:
794:
790:
785:
780:
776:
772:
768:
764:
760:
756:
752:
748:
747:
742:
740:
733:
732:
728:
725:
714:on 2021-11-05
710:
703:
699:
692:
689:
684:
680:
676:
672:
669:(2): 229–32.
668:
664:
660:
653:
650:
645:
641:
637:
633:
628:
623:
619:
615:
611:
604:
601:
596:
592:
587:
582:
578:
574:
570:
568:
559:
556:
551:
547:
542:
537:
532:
527:
523:
519:
515:
508:
505:
500:
496:
492:
488:
485:(3): 243–71.
484:
480:
473:
466:
464:
460:
455:
451:
447:
443:
439:
435:
431:
427:
424:(2): 157–69.
423:
419:
412:
410:
406:
401:
394:
391:
384:
382:
380:
378:
372:
356:
352:
340:
335:
332:
329:
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323:
320:
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312:
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240:
236:
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228:
220:
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208:
204:
200:
197:
193:
189:
188:cyanobacteria
185:
181:
178:
174:
171:
167:
163:
160:
156:
144:
141:
139:
135:
132:
128:
124:
121:
119:
115:
111:
107:
104:
101:
97:
92:
88:
85:
82:
80:
76:
73:
70:
68:
64:
61:Cytochrom_B_C
60:
56:
51:
47:
41:
36:
31:
19:
1592:
1570:Cytochrome b
1569:
1532:
1511:Metmyoglobin
1497:
1302:
1128:development:
1125:
1095:
1078:
1066:
1054:
1039:
1022:
1010:
998:
976:
964:
931:hemoproteins
823:
817:
811:
761:): 877–892.
750:
744:
738:
727:
716:. Retrieved
709:the original
691:
666:
662:
658:
652:
617:
613:
603:
576:
572:
566:
565:"Cytochrome
558:
521:
517:
507:
482:
478:
421:
418:J. Mol. Evol
417:
399:
393:
376:
344:
310:
296:
292:
290:
283:
266:phylogenetic
259:
251:
224:
184:chloroplasts
162:mitochondria
155:Cytochrome b
154:
153:
18:Cytochrome-b
1518:Neuroglobin
1444:Other human
1157:HbE Gower 2
1143:HbE Gower 1
307:Human genes
173:complex III
166:prokaryotes
53:Identifiers
1609:Categories
1565:Cytochrome
1523:Cytoglobin
1303:pathology:
1126:stages of
1041:Beta locus
949:Hemoglobin
718:2021-06-16
385:References
301:atovaquone
297:P. berghei
159:eukaryotic
106:structures
1593:see also
1506:Myoglobin
1409:Compounds
1280:HbF/Fetal
1210:HbF/Fetal
1136:Embryonic
1117:Tetramers
862:205345358
846:0191-2917
830:: 59–64.
775:1464-6722
199:1.10.99.1
84:IPR005798
1465:Nonhuman
957:Subunits
923:Proteins
854:30422743
801:93002697
793:30945788
683:18248769
644:13938075
636:16008558
595:11264397
550:33464892
270:families
209:). This
180:1.10.2.2
123:RCSB PDB
79:InterPro
940:Globins
784:6637890
541:7908018
499:8329437
454:7298013
446:2509716
426:Bibcode
328:CYBASC3
247:ligands
72:PF00032
1533:plant:
1498:human:
992:pseudo
888:(MeSH)
860:
852:
844:
799:
791:
781:
773:
696:FRAC (
681:
642:
634:
614:FEBS J
593:
548:
538:
497:
452:
444:
334:MT-CYB
274:genera
138:PDBsum
112:
102:
58:Symbol
1558:Other
1490:Other
1321:Barts
1242:Adult
1203:Fetal
858:S2CID
826:(1).
797:S2CID
753:(6).
712:(PDF)
705:(PDF)
640:S2CID
475:(PDF)
450:S2CID
366:F129L
360:G143A
322:CYB5B
316:CYB5A
1101:HBE1
1089:HBG2
1084:HBG1
1016:HBQ1
987:HBA2
982:HBA1
927:heme
850:PMID
842:ISSN
789:PMID
771:ISSN
679:PMID
632:PMID
591:PMID
546:PMID
495:PMID
483:1143
442:PMID
363:and
295:and
272:and
243:heme
186:and
131:PDBj
127:PDBe
110:ECOD
100:Pfam
67:Pfam
1387:HbO
1373:HbE
1359:HbC
1345:HbS
1331:HbD
1311:HbH
1263:HbA
1249:HbA
1224:HbA
1072:HBD
1060:HBB
1043:on
1028:HBM
1004:HBZ
832:doi
824:103
779:PMC
763:doi
759:W-B
671:doi
622:doi
618:272
581:doi
536:PMC
526:doi
522:121
487:doi
434:doi
375:in
215:ATP
207:PMF
118:PDB
1611::
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1375:(α
1361:(α
1347:(α
1333:(α
1323:(γ
1313:(β
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196:EC
177:EC
129:;
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108:/
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1272:δ
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1179:2
1177:γ
1175:2
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1165:2
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1161:2
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1096:ε
1079:γ
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349:o
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