321:
298:
195:
220:
2651:
40:
327:
226:
4828:
4848:
1404:
synapses. This enzyme is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo
66:
2353:
Tsujimura K, Tanaka J, Ando S, Matsuoka Y, Kusubata M, Sugiura H, et al. (August 1994). "Identification of phosphorylation sites on glial fibrillary acidic protein for cdc2 kinase and Ca(2+)-calmodulin-dependent protein kinase II".
2312:"Microtubule-associated protein/microtubule affinity-regulating kinase (p110mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262"
2691:
2114:
Tokui T, Yamauchi T, Yano T, Nishi Y, Kusagawa M, Yatani R, Inagaki M (June 1990). "Ca2(+)-calmodulin-dependent protein kinase II phosphorylates various types of non-epithelial intermediate filament proteins".
2976:
2081:"Nitric oxide synthase regulatory sites. Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase; identification of flavin and calmodulin binding sites"
2684:
1768:"The cyclin-dependent kinase 5 activators p35 and p39 interact with the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II and alpha-actinin-1 in a calcium-dependent manner"
1405:
autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. According to a 2018 study by
2677:
334:
233:
2884:
1546:"Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro"
3432:
1389:
1347:
4271:
2735:
4380:
3118:
3005:
2650:
2385:"Identification of Ser38 as the site in cardiac sarcoplasmic reticulum Ca(2+)-ATPase that is phosphorylated by Ca2+/calmodulin-dependent protein kinase"
1011:
156:
3393:
992:
2463:"Identification of a phosphorylation site for calcium/calmodulindependent protein kinase II in the NR2B subunit of the N-methyl-D-aspartate receptor"
4366:
3831:
2722:
2704:
1385:
4468:
4349:
4922:
4055:
2924:
4893:
4119:
3094:
2630:
1526:
4912:
4375:
2269:"Identification of the major physiologic phosphorylation site of human keratin 18: potential kinases and a role in filament reorganization"
1508:
320:
2909:
2590:
1267:
4432:
4107:
1274:
297:
4547:
3364:
3354:
3039:
2181:"Ca2+/calmodulin-dependent protein kinase II: localization in the interphase nucleus and the mitotic apparatus of mammalian cells"
4046:
2506:"Mice expressing activated CaMKII lack low frequency LTP and do not form stable place cells in the CA1 region of the hippocampus"
1719:"Densin-180 forms a ternary complex with the (alpha)-subunit of Ca2+/calmodulin-dependent protein kinase II and (alpha)-actinin"
1644:
4315:
3987:
3349:
3340:
1495:
1474:
4703:
2596:
1491:
2420:"A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity"
219:
194:
63:
3730:
3227:
3218:
2875:
2821:
4818:
1991:
Wegner M, Cao Z, Rosenfeld MG (April 1992). "Calcium-regulated phosphorylation within the leucine zipper of C/EBP beta".
1470:
2918:
1401:
136:
1426:
333:
232:
2669:
3942:
3760:
3256:
326:
225:
4688:
4886:
4804:
4791:
4778:
4765:
4752:
4739:
4726:
3932:
3927:
3922:
3912:
3907:
3902:
3892:
3687:
3462:
3058:
2623:
4698:
4652:
4595:
4155:
4146:
4097:
2863:
2708:
2146:"Phosphorylation sites linked to glial filament disassembly in vitro locate in a non-alpha-helical head domain"
1056:
144:
4600:
4455:
3878:
1410:
1037:
4621:
4540:
3154:
4693:
2549:"The regulatory Ser262 of microtubule-associated protein tau is phosphorylated by phosphorylase kinase"
127:, CAMKA, calcium/calmodulin dependent protein kinase II alpha, MRD53, CaMKIINalpha, MRT63, CaMKIIalpha
4879:
3721:
2616:
2192:
2000:
1598:
208:
2310:
Drewes G, Trinczek B, Illenberger S, Biernat J, Schmitt-Ulms G, Meyer HE, et al. (March 1995).
123:
4657:
2602:
1397:
1250:
1246:
1234:
1213:
1209:
1205:
1163:
1142:
1138:
1134:
4229:
1815:
Gardoni F, Mauceri D, Fiorentini C, Bellone C, Missale C, Cattabeni F, Di Luca M (November 2003).
4917:
4590:
4332:
4286:
2535:
2492:
2341:
2024:
1894:
1846:
1414:
1393:
168:
1242:
1238:
1201:
1197:
1171:
1167:
1130:
1126:
1544:
Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, et al. (February 1999).
3592:
3301:
2570:
2527:
2484:
2449:
2406:
2371:
2333:
2298:
2255:
2220:
2167:
2132:
2102:
2067:
2016:
1979:
1958:"Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase"
1944:
1923:
1886:
1838:
1797:
1748:
1695:
1626:
1567:
116:
56:
4863:
1585:
Lin CR, Kapiloff MS, Durgerian S, Tatemoto K, Russo AF, Hanson P, et al. (August 1987).
4636:
4631:
4605:
4533:
4185:
3427:
3417:
3412:
3330:
3321:
3251:
3242:
3188:
3179:
2836:
2560:
2517:
2474:
2439:
2431:
2396:
2363:
2323:
2288:
2280:
2245:
2210:
2200:
2157:
2124:
2092:
2057:
2049:
2008:
1969:
1915:
1878:
1828:
1787:
1779:
1738:
1730:
1685:
1675:
1616:
1606:
1557:
413:
344:
288:
243:
164:
2418:
Rivera VM, Miranti CK, Misra RP, Ginty DD, Chen RH, Blenis J, Greenberg ME (October 1993).
4683:
4667:
4580:
4011:
3082:
3077:
3072:
2367:
1714:
1433:
1406:
1359:
388:
2196:
2004:
1602:
39:
4832:
4721:
4662:
2293:
2268:
2144:
Inagaki M, Gonda Y, Nishizawa K, Kitamura S, Sato C, Ando S, et al. (March 1990).
2062:
2037:
1906:
Hook SS, Means AR (2001). "Ca(2+)/CaM-dependent kinases: from activation to function".
1792:
1783:
1767:
1743:
1734:
1718:
1690:
1659:
1645:"Entrez Gene: CAMK2A calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha"
1351:
2565:
2548:
2522:
2505:
2444:
2419:
2401:
2384:
2250:
2233:
2162:
2145:
2097:
2080:
1974:
1957:
1919:
1882:
1621:
1586:
926:
921:
916:
911:
906:
901:
896:
891:
886:
881:
876:
871:
866:
861:
856:
851:
846:
841:
836:
831:
826:
821:
816:
811:
806:
801:
796:
791:
775:
770:
765:
760:
755:
750:
745:
740:
735:
730:
725:
720:
715:
710:
705:
700:
695:
690:
685:
669:
664:
659:
654:
649:
644:
639:
634:
629:
624:
619:
614:
609:
604:
4906:
4626:
4585:
3135:
3067:
2215:
2180:
2128:
591:
2539:
2038:"PKC epsilon-related kinase associates with and phosphorylates cytokeratin 8 and 18"
2028:
1898:
1850:
4859:
4575:
4006:
2831:
2496:
2345:
1664:
mutation causes growth delay, frequent seizures and severe intellectual disability"
1587:"Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase"
406:
185:
148:
2012:
172:
4799:
4734:
4570:
4212:
3844:
3784:
3667:
3587:
3311:
1658:
Chia PH, Zhong FL, Niwa S, Bonnard C, Utami KH, Zeng R, et al. (May 2018).
1531:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1513:
National Center for
Biotechnology Information, U.S. National Library of Medicine
4827:
2185:
Proceedings of the
National Academy of Sciences of the United States of America
1591:
Proceedings of the
National Academy of Sciences of the United States of America
822:
regulation of mitochondrial membrane permeability involved in apoptotic process
489:
4300:
2774:
2383:
Toyofuku T, Curotto
Kurzydlowski K, Narayanan N, MacLennan DH (October 1994).
305:
202:
152:
2479:
2462:
4773:
4747:
3261:
2328:
2311:
2205:
1869:
Soderling TR (June 2000). "CaM-kinases: modulators of synaptic plasticity".
1611:
1562:
1545:
956:
549:
427:
372:
359:
271:
258:
160:
2435:
1948:
1927:
1890:
1842:
1833:
1816:
1801:
1752:
1699:
1571:
2574:
2531:
2504:
Rotenberg A, Mayford M, Hawkins RD, Kandel ER, Muller RU (December 1996).
2488:
2453:
2410:
2375:
2337:
2302:
2284:
2259:
2224:
2171:
2136:
2106:
2071:
2053:
2036:
Omary MB, Baxter GT, Chou CF, Riopel CL, Lin WY, Strulovici B (May 1992).
2020:
1983:
1630:
1314:
1309:
3617:
3512:
3507:
3502:
2461:
Omkumar RV, Kiely MJ, Rosenstein AJ, Min KT, Kennedy MB (December 1996).
1298:
1101:
1082:
2234:"Protein kinase A phosphorylates retinal phosducin on serine 73 in situ"
1680:
1409:, the recessive mutation of CAMK2A in humans cause a syndrome of severe
4276:
4254:
4249:
4239:
4234:
4036:
4031:
4026:
4021:
4016:
4001:
3996:
3647:
3612:
2851:
2846:
2841:
1766:
Dhavan R, Greer PL, Morabito MA, Orlando LR, Tsai LH (September 2002).
1362:
1068:
1023:
17:
93:
89:
85:
4786:
4556:
4506:
4501:
4496:
4491:
4486:
4481:
4476:
4427:
4422:
4417:
4412:
4407:
4390:
4385:
4259:
4244:
4195:
4190:
4175:
4170:
4165:
4160:
4134:
4129:
4124:
4112:
4090:
4085:
3977:
3952:
3627:
3452:
3447:
3442:
3437:
3422:
3266:
3203:
3198:
3193:
3169:
2995:
2990:
2964:
2959:
2954:
2944:
2939:
2929:
2769:
2700:
1439:
1381:
1355:
1282:
978:
4847:
1817:"CaMKII-dependent phosphorylation regulates SAP97/NR2A interaction"
4760:
4402:
4395:
4305:
4202:
4102:
4080:
4075:
4070:
4065:
4060:
3972:
3967:
3962:
3957:
3947:
3917:
3897:
3774:
3769:
3750:
3745:
3735:
3711:
3706:
3701:
3677:
3672:
3662:
3657:
3652:
3642:
3622:
3607:
3602:
3597:
3577:
3572:
3562:
3557:
3552:
3547:
3542:
3532:
3527:
3522:
3517:
3497:
3492:
3487:
3482:
3477:
3472:
3457:
3407:
3402:
3296:
3291:
3286:
3281:
3276:
3271:
3232:
3164:
3159:
3108:
3103:
3029:
3024:
3019:
2985:
2977:
3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase
2779:
2764:
2759:
2754:
2749:
2744:
2659:: CRYSTAL STRUCTURE OF CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE
1327:
Calcium/calmodulin-dependent protein kinase type II subunit alpha
941:
937:
4855:
4295:
4222:
4217:
4207:
4180:
3937:
3887:
3868:
3863:
3858:
3853:
3808:
3803:
3798:
3793:
3740:
3696:
3637:
3632:
3582:
3567:
3537:
3467:
3383:
3378:
3373:
3306:
3208:
3149:
3144:
3048:
3014:
2899:
2894:
2889:
2858:
2826:
2814:
2809:
2804:
2794:
2789:
1445:
1369:
140:
4529:
4453:
3829:
2720:
2673:
2612:
4264:
2799:
2784:
2608:
837:
positive regulation of NF-kappaB transcription factor activity
1713:
Walikonis RS, Oguni A, Khorosheva EM, Jeng CJ, Asuncion FJ,
812:
positive regulation of cardiac muscle cell apoptotic process
4525:
665:
calcium-dependent protein serine/threonine kinase activity
1937:
Tanpakushitsu
Kakusan Koso. Protein, Nucleic Acid, Enzyme
751:
calcium- and calmodulin-dependent protein kinase complex
396:
4867:
4816:
561:
4712:
4676:
4645:
4614:
4563:
4467:
4365:
4348:
4331:
4314:
4285:
4145:
4045:
3986:
3877:
3843:
3783:
3759:
3720:
3686:
3392:
3363:
3339:
3320:
3241:
3217:
3178:
3134:
3117:
3093:
3057:
3038:
3004:
2975:
2908:
2874:
2734:
2117:
1227:
1190:
1156:
1119:
500:
dentate gyrus of hippocampal formation granule cell
1487:
1485:
1483:
1466:
1464:
1462:
1956:Countaway JL, Nairn AC, Davis RJ (January 1992).
872:Wnt signaling pathway, calcium modulating pathway
343:
242:
27:Protein-coding gene in the species Homo sapiens
2232:Lee RH, Brown BM, Lolley RN (September 1990).
1492:GRCm38: Ensembl release 89: ENSMUSG00000024617
4887:
4541:
2736:Non-specific serine/threonine protein kinases
2685:
2624:
8:
2079:Bredt DS, Ferris CD, Snyder SH (June 1992).
1908:Annual Review of Pharmacology and Toxicology
1396:signaling is crucial for several aspects of
862:positive regulation of calcium ion transport
660:calmodulin-dependent protein kinase activity
1471:GRCh38: Ensembl release 89: ENSG00000070808
797:interferon-gamma-mediated signaling pathway
4894:
4880:
4548:
4534:
4526:
4464:
4450:
3840:
3826:
3119:Goodpasture-antigen-binding protein kinase
2731:
2717:
2692:
2678:
2670:
2631:
2617:
2609:
952:
847:regulation of neuronal synaptic plasticity
587:
384:
283:
180:
74:
3832:Serine/threonine-specific protein kinases
3006:(isocitrate dehydrogenase (NADP+)) kinase
2723:Serine/threonine-specific protein kinases
2705:Serine/threonine-specific protein kinases
2564:
2521:
2478:
2443:
2400:
2327:
2292:
2249:
2214:
2204:
2161:
2096:
2061:
1973:
1832:
1791:
1742:
1689:
1679:
1620:
1610:
1561:
1390:Ca/calmodulin-dependent protein kinase II
4367:Receptor protein serine/threonine kinase
2179:Ohta Y, Ohba T, Miyamoto E (July 1990).
1386:serine/threonine-specific protein kinase
817:regulation of neurotransmitter secretion
650:protein serine/threonine kinase activity
4823:
4350:Low-density-lipoprotein receptor kinase
2646:
1458:
842:regulation of cellular response to heat
807:angiotensin-activated signaling pathway
922:peptidyl-threonine autophosphorylation
917:regulation of synaptic vesicle docking
29:
3095:Fas-activated serine/threonine kinase
2368:10.1093/oxfordjournals.jbchem.a124542
1380:The product of the CAMK2A gene is an
1334:
907:G1/S transition of mitotic cell cycle
348:
309:
304:
247:
206:
201:
7:
4844:
4842:
4376:Bone morphogenetic protein receptors
2910:Dephospho-(reductase kinase) kinase
2553:The Journal of Biological Chemistry
2467:The Journal of Biological Chemistry
2389:The Journal of Biological Chemistry
2316:The Journal of Biological Chemistry
2238:The Journal of Biological Chemistry
2150:The Journal of Biological Chemistry
2085:The Journal of Biological Chemistry
1962:The Journal of Biological Chemistry
1821:The Journal of Biological Chemistry
1365:) that in humans is encoded by the
4866:. You can help Knowledge (XXG) by
3365:G-protein coupled receptor kinases
1784:10.1523/JNEUROSCI.22-18-07879.2002
1735:10.1523/JNEUROSCI.21-02-00423.2001
1224:
1187:
1153:
1116:
1092:
1073:
1047:
1028:
1002:
983:
887:peptidyl-threonine phosphorylation
566:
484:
422:
401:
25:
3355:Beta adrenergic receptor kinase-2
3040:(tyrosine 3-monooxygenase) kinase
1920:10.1146/annurev.pharmtox.41.1.471
897:intracellular signal transduction
776:Schaffer collateral - CA1 synapse
620:protein homodimerization activity
4846:
4826:
4047:Mitogen-activated protein kinase
2649:
2267:Ku NO, Omary MB (October 1994).
332:
325:
319:
296:
231:
224:
218:
193:
38:
4433:Anti-Müllerian hormone receptor
4316:(acetyl-CoA carboxylase) kinase
3988:(RNA-polymerase)-subunit kinase
3350:Beta adrenergic receptor kinase
3341:Beta adrenergic receptor kinase
1871:Current Opinion in Neurobiology
1660:"A homozygous loss-of-function
882:peptidyl-serine phosphorylation
4056:Extracellular signal-regulated
2424:Molecular and Cellular Biology
927:regulation of neuron migration
550:More reference expression data
450:Region I of hippocampus proper
1:
4923:Human chromosome 5 gene stubs
4120:P38 mitogen-activated protein
3219:cGMP-dependent protein kinase
3180:cAMP-dependent protein kinase
2876:Pyruvate dehydrogenase kinase
2822:Ataxia telangiectasia mutated
2566:10.1016/S0021-9258(19)67481-8
2523:10.1016/S0092-8674(00)81829-2
2402:10.1016/S0021-9258(18)47221-3
2251:10.1016/S0021-9258(18)55478-8
2163:10.1016/S0021-9258(19)39622-X
2098:10.1016/S0021-9258(19)49862-1
1975:10.1016/S0021-9258(18)48406-2
1935:Yamamoto H (March 2002). "".
1883:10.1016/S0959-4388(00)00090-8
317:
216:
2919:AMP-activated protein kinase
2129:10.1016/0006-291X(90)91977-Z
2013:10.1126/science.256.5055.370
4913:Genes on human chromosome 5
3834:(EC 2.7.11.21-EC 2.7.11.30)
2273:The Journal of Cell Biology
2042:The Journal of Cell Biology
1772:The Journal of Neuroscience
1723:The Journal of Neuroscience
912:dendritic spine development
852:protein autophosphorylation
4939:
4841:
3761:Elongation factor 2 kinase
2725:(EC 2.7.11.1-EC 2.7.11.20)
2601:gene details page in the
2547:Paudel HK (January 1997).
877:nervous system development
686:endocytic vesicle membrane
635:glutamate receptor binding
4704:Michaelis–Menten kinetics
4463:
4449:
4156:MAP kinase kinase kinases
3839:
3825:
3688:Myosin light-chain kinase
3394:Ca2+/calmodulin-dependent
3059:Myosin-heavy-chain kinase
2730:
2716:
2644:
1527:"Mouse PubMed Reference:"
1509:"Human PubMed Reference:"
1425:CAMK2A has been shown to
1313:
1308:
1304:
1297:
1281:
1268:Chr 5: 150.22 – 150.29 Mb
1262:
1231:
1194:
1183:
1160:
1123:
1112:
1099:
1095:
1080:
1076:
1067:
1054:
1050:
1035:
1031:
1022:
1009:
1005:
990:
986:
977:
962:
955:
951:
935:
670:identical protein binding
590:
586:
574:
569:
560:
547:
496:
487:
462:anterior cingulate cortex
434:
425:
395:
387:
383:
366:
353:
316:
295:
286:
282:
265:
252:
215:
192:
183:
179:
134:
131:
121:
114:
109:
82:
77:
60:
55:
50:
46:
37:
32:
4596:Diffusion-limited enzyme
4456:Dual-specificity kinases
2480:10.1074/jbc.271.49.31670
1275:Chr 18: 61.06 – 61.12 Mb
520:anterior amygdaloid area
3879:Cyclin-dependent kinase
2356:Journal of Biochemistry
2329:10.1074/jbc.270.13.7679
2206:10.1073/pnas.87.14.5341
1612:10.1073/pnas.84.16.5962
1411:intellectual disability
1388:family, as well as the
1339:Ca/calmodulin-dependent
902:protein phosphorylation
615:protein kinase activity
2436:10.1128/mcb.13.10.6260
1834:10.1074/jbc.M303576200
867:dendrite morphogenesis
508:lateral septal nucleus
504:superior frontal gyrus
350:18 E1|18 34.41 cM
4689:Eadie–Hofstee diagram
4622:Allosteric regulation
2285:10.1083/jcb.127.1.161
2054:10.1083/jcb.117.3.583
1563:10.1093/dnares/6.1.63
857:calcium ion transport
771:postsynaptic membrane
532:primary visual cortex
311:Chromosome 18 (mouse)
4699:Lineweaver–Burk plot
3722:Phosphorylase kinase
2595:genome location and
1384:that belongs to the
1346:, is one subunit of
892:cell differentiation
832:response to ischemia
741:postsynaptic density
721:presynaptic membrane
605:transferase activity
470:orbitofrontal cortex
209:Chromosome 5 (human)
78:List of PDB id codes
51:Available structures
2603:UCSC Genome Browser
2197:1990PNAS...87.5341O
2005:1992Sci...256..370W
1681:10.7554/eLife.32451
1603:1987PNAS...84.5962L
1398:synaptic plasticity
4854:This article on a
4658:Enzyme superfamily
4591:Enzyme promiscuity
4333:Tropomyosin kinase
4287:Tau-protein kinase
1415:growth retardation
1057:ENSMUSG00000024617
785:Biological process
679:Cellular component
655:calmodulin binding
610:nucleotide binding
598:Molecular function
512:olfactory tubercle
446:right frontal lobe
173:CAMK2A - orthologs
4875:
4874:
4814:
4813:
4523:
4522:
4519:
4518:
4515:
4514:
4445:
4444:
4441:
4440:
3821:
3820:
3817:
3816:
3302:Protein kinase N1
3257:Protein kinase Cζ
2667:
2666:
1324:
1323:
1320:
1319:
1293:
1292:
1258:
1257:
1221:
1220:
1179:
1178:
1150:
1149:
1108:
1107:
1089:
1088:
1063:
1062:
1044:
1043:
1018:
1017:
999:
998:
947:
946:
746:neuron projection
645:metal ion binding
582:
581:
578:
577:
556:
555:
543:
542:
536:perirhinal cortex
481:
480:
442:prefrontal cortex
379:
378:
278:
277:
105:
104:
101:
100:
61:Ortholog search:
16:(Redirected from
4930:
4896:
4889:
4882:
4850:
4843:
4831:
4830:
4822:
4694:Hanes–Woolf plot
4637:Enzyme activator
4632:Enzyme inhibitor
4606:Enzyme catalysis
4550:
4543:
4536:
4527:
4465:
4451:
4098:C-Jun N-terminal
3841:
3827:
3331:Rhodopsin kinase
3322:Rhodopsin kinase
3252:Protein kinase C
3243:Protein kinase C
3228:Protein kinase G
3189:Protein kinase A
2800:Protein kinase B
2732:
2718:
2694:
2687:
2680:
2671:
2653:
2633:
2626:
2619:
2610:
2578:
2568:
2543:
2525:
2500:
2482:
2457:
2447:
2414:
2404:
2379:
2349:
2331:
2306:
2296:
2263:
2253:
2228:
2218:
2208:
2175:
2165:
2140:
2110:
2100:
2091:(16): 10976–81.
2075:
2065:
2032:
1987:
1977:
1952:
1931:
1902:
1855:
1854:
1836:
1827:(45): 44745–52.
1812:
1806:
1805:
1795:
1763:
1757:
1756:
1746:
1717:(January 2001).
1710:
1704:
1703:
1693:
1683:
1655:
1649:
1648:
1641:
1635:
1634:
1624:
1614:
1582:
1576:
1575:
1565:
1541:
1535:
1534:
1523:
1517:
1516:
1505:
1499:
1489:
1478:
1468:
1344:
1340:
1336:
1306:
1305:
1277:
1270:
1253:
1225:
1216:
1188:
1184:RefSeq (protein)
1174:
1154:
1145:
1117:
1093:
1074:
1048:
1029:
1003:
984:
953:
588:
567:
552:
492:
490:Top expressed in
485:
474:Brodmann area 46
430:
428:Top expressed in
423:
402:
385:
375:
362:
351:
336:
329:
323:
312:
300:
284:
274:
261:
250:
235:
228:
222:
211:
197:
181:
175:
126:
119:
96:
75:
69:
48:
47:
42:
30:
21:
4938:
4937:
4933:
4932:
4931:
4929:
4928:
4927:
4903:
4902:
4901:
4900:
4839:
4837:
4825:
4817:
4815:
4810:
4722:Oxidoreductases
4708:
4684:Enzyme kinetics
4672:
4668:List of enzymes
4641:
4610:
4581:Catalytic triad
4559:
4554:
4524:
4511:
4459:
4437:
4361:
4344:
4327:
4310:
4281:
4141:
4041:
4012:P70-S6 Kinase 1
3982:
3873:
3835:
3813:
3779:
3755:
3716:
3682:
3388:
3359:
3335:
3316:
3237:
3213:
3174:
3130:
3113:
3089:
3083:Aurora C kinase
3078:Aurora B kinase
3073:Aurora A kinase
3053:
3034:
3000:
2971:
2904:
2870:
2726:
2712:
2698:
2668:
2663:
2660:
2654:
2640:
2637:
2586:
2581:
2546:
2503:
2473:(49): 31670–8.
2460:
2430:(10): 6260–73.
2417:
2395:(42): 26492–6.
2382:
2352:
2322:(13): 7679–88.
2309:
2266:
2244:(26): 15860–6.
2231:
2178:
2143:
2113:
2078:
2035:
1999:(5055): 370–3.
1990:
1955:
1934:
1905:
1868:
1864:
1862:Further reading
1859:
1858:
1814:
1813:
1809:
1778:(18): 7879–91.
1765:
1764:
1760:
1712:
1711:
1707:
1657:
1656:
1652:
1643:
1642:
1638:
1584:
1583:
1579:
1543:
1542:
1538:
1525:
1524:
1520:
1507:
1506:
1502:
1490:
1481:
1469:
1460:
1455:
1434:Actinin alpha 4
1423:
1407:Bruno Reversade
1378:
1342:
1341:protein kinase
1338:
1315:View/Edit Mouse
1310:View/Edit Human
1273:
1266:
1263:Location (UCSC)
1249:
1245:
1241:
1237:
1233:
1212:
1208:
1204:
1200:
1196:
1170:
1166:
1162:
1141:
1137:
1133:
1129:
1125:
1038:ENSG00000070808
931:
792:phosphorylation
780:
766:dendritic spine
761:cell projection
701:plasma membrane
674:
630:protein binding
625:kinase activity
548:
539:
534:
530:
526:
524:piriform cortex
522:
518:
516:muscle of thigh
514:
510:
506:
502:
488:
477:
472:
468:
464:
460:
458:cingulate gyrus
456:
454:Brodmann area 9
452:
448:
444:
440:
426:
370:
357:
349:
339:
338:
337:
330:
310:
287:Gene location (
269:
256:
248:
238:
237:
236:
229:
207:
184:Gene location (
135:
122:
115:
84:
62:
28:
23:
22:
15:
12:
11:
5:
4936:
4934:
4926:
4925:
4920:
4915:
4905:
4904:
4899:
4898:
4891:
4884:
4876:
4873:
4872:
4851:
4836:
4835:
4812:
4811:
4809:
4808:
4795:
4782:
4769:
4756:
4743:
4730:
4716:
4714:
4710:
4709:
4707:
4706:
4701:
4696:
4691:
4686:
4680:
4678:
4674:
4673:
4671:
4670:
4665:
4660:
4655:
4649:
4647:
4646:Classification
4643:
4642:
4640:
4639:
4634:
4629:
4624:
4618:
4616:
4612:
4611:
4609:
4608:
4603:
4598:
4593:
4588:
4583:
4578:
4573:
4567:
4565:
4561:
4560:
4555:
4553:
4552:
4545:
4538:
4530:
4521:
4520:
4517:
4516:
4513:
4512:
4510:
4509:
4504:
4499:
4494:
4489:
4484:
4479:
4473:
4471:
4461:
4460:
4454:
4447:
4446:
4443:
4442:
4439:
4438:
4436:
4435:
4430:
4425:
4420:
4415:
4410:
4405:
4400:
4399:
4398:
4393:
4388:
4383:
4372:
4370:
4369:(EC 2.7.11.30)
4363:
4362:
4360:
4359:
4355:
4353:
4352:(EC 2.7.11.29)
4346:
4345:
4343:
4342:
4338:
4336:
4335:(EC 2.7.11.28)
4329:
4328:
4326:
4325:
4321:
4319:
4318:(EC 2.7.11.27)
4312:
4311:
4309:
4308:
4303:
4298:
4292:
4290:
4289:(EC 2.7.11.26)
4283:
4282:
4280:
4279:
4274:
4269:
4268:
4267:
4262:
4257:
4252:
4247:
4242:
4237:
4227:
4226:
4225:
4220:
4215:
4210:
4200:
4199:
4198:
4193:
4188:
4183:
4178:
4173:
4168:
4163:
4152:
4150:
4149:(EC 2.7.11.25)
4143:
4142:
4140:
4139:
4138:
4137:
4132:
4127:
4117:
4116:
4115:
4110:
4105:
4095:
4094:
4093:
4088:
4083:
4078:
4073:
4068:
4063:
4052:
4050:
4049:(EC 2.7.11.24)
4043:
4042:
4040:
4039:
4034:
4029:
4024:
4019:
4014:
4009:
4004:
3999:
3993:
3991:
3990:(EC 2.7.11.23)
3984:
3983:
3981:
3980:
3975:
3970:
3965:
3960:
3955:
3950:
3945:
3940:
3935:
3930:
3925:
3920:
3915:
3910:
3905:
3900:
3895:
3890:
3884:
3882:
3881:(EC 2.7.11.22)
3875:
3874:
3872:
3871:
3866:
3861:
3856:
3850:
3848:
3847:(EC 2.7.11.21)
3837:
3836:
3830:
3823:
3822:
3819:
3818:
3815:
3814:
3812:
3811:
3806:
3801:
3796:
3790:
3788:
3787:(EC 2.7.11.21)
3781:
3780:
3778:
3777:
3772:
3766:
3764:
3763:(EC 2.7.11.20)
3757:
3756:
3754:
3753:
3748:
3743:
3738:
3733:
3727:
3725:
3724:(EC 2.7.11.19)
3718:
3717:
3715:
3714:
3709:
3704:
3699:
3693:
3691:
3690:(EC 2.7.11.18)
3684:
3683:
3681:
3680:
3675:
3670:
3665:
3660:
3655:
3650:
3645:
3640:
3635:
3630:
3625:
3620:
3615:
3610:
3605:
3600:
3595:
3590:
3585:
3580:
3575:
3570:
3565:
3560:
3555:
3550:
3545:
3540:
3535:
3530:
3525:
3520:
3515:
3510:
3505:
3500:
3495:
3490:
3485:
3480:
3475:
3470:
3465:
3460:
3455:
3450:
3445:
3440:
3435:
3430:
3425:
3420:
3415:
3410:
3405:
3399:
3397:
3396:(EC 2.7.11.17)
3390:
3389:
3387:
3386:
3381:
3376:
3370:
3368:
3367:(EC 2.7.11.16)
3361:
3360:
3358:
3357:
3352:
3346:
3344:
3343:(EC 2.7.11.15)
3337:
3336:
3334:
3333:
3327:
3325:
3324:(EC 2.7.11.14)
3318:
3317:
3315:
3314:
3309:
3304:
3299:
3294:
3289:
3284:
3279:
3274:
3269:
3264:
3259:
3254:
3248:
3246:
3245:(EC 2.7.11.13)
3239:
3238:
3236:
3235:
3230:
3224:
3222:
3221:(EC 2.7.11.12)
3215:
3214:
3212:
3211:
3206:
3201:
3196:
3191:
3185:
3183:
3182:(EC 2.7.11.11)
3176:
3175:
3173:
3172:
3167:
3162:
3157:
3152:
3147:
3141:
3139:
3138:(EC 2.7.11.10)
3132:
3131:
3129:
3128:
3124:
3122:
3115:
3114:
3112:
3111:
3106:
3100:
3098:
3091:
3090:
3088:
3087:
3086:
3085:
3080:
3075:
3064:
3062:
3055:
3054:
3052:
3051:
3045:
3043:
3036:
3035:
3033:
3032:
3027:
3022:
3017:
3011:
3009:
3002:
3001:
2999:
2998:
2993:
2988:
2982:
2980:
2973:
2972:
2970:
2969:
2968:
2967:
2962:
2957:
2949:
2948:
2947:
2942:
2934:
2933:
2932:
2927:
2915:
2913:
2906:
2905:
2903:
2902:
2897:
2892:
2887:
2881:
2879:
2872:
2871:
2869:
2868:
2867:
2866:
2856:
2855:
2854:
2849:
2844:
2839:
2829:
2824:
2819:
2818:
2817:
2812:
2807:
2797:
2792:
2787:
2782:
2777:
2772:
2767:
2762:
2757:
2752:
2747:
2741:
2739:
2728:
2727:
2721:
2714:
2713:
2699:
2697:
2696:
2689:
2682:
2674:
2665:
2664:
2662:
2661:
2655:
2648:
2645:
2642:
2641:
2638:
2636:
2635:
2628:
2621:
2613:
2607:
2606:
2585:
2584:External links
2582:
2580:
2579:
2559:(3): 1777–85.
2544:
2516:(7): 1351–61.
2501:
2458:
2415:
2380:
2350:
2307:
2264:
2229:
2191:(14): 5341–5.
2176:
2141:
2123:(3): 896–904.
2111:
2076:
2033:
1988:
1968:(2): 1129–40.
1953:
1932:
1914:(1): 471–505.
1903:
1865:
1863:
1860:
1857:
1856:
1807:
1758:
1705:
1650:
1636:
1597:(16): 5962–6.
1577:
1536:
1518:
1500:
1479:
1457:
1456:
1454:
1451:
1450:
1449:
1443:
1437:
1422:
1419:
1377:
1374:
1360:phosphorylates
1352:protein kinase
1322:
1321:
1318:
1317:
1312:
1302:
1301:
1295:
1294:
1291:
1290:
1288:
1286:
1279:
1278:
1271:
1264:
1260:
1259:
1256:
1255:
1229:
1228:
1222:
1219:
1218:
1192:
1191:
1185:
1181:
1180:
1177:
1176:
1158:
1157:
1151:
1148:
1147:
1121:
1120:
1114:
1110:
1109:
1106:
1105:
1097:
1096:
1090:
1087:
1086:
1078:
1077:
1071:
1065:
1064:
1061:
1060:
1052:
1051:
1045:
1042:
1041:
1033:
1032:
1026:
1020:
1019:
1016:
1015:
1007:
1006:
1000:
997:
996:
988:
987:
981:
975:
974:
969:
964:
960:
959:
949:
948:
945:
944:
933:
932:
930:
929:
924:
919:
914:
909:
904:
899:
894:
889:
884:
879:
874:
869:
864:
859:
854:
849:
844:
839:
834:
829:
824:
819:
814:
809:
804:
799:
794:
788:
786:
782:
781:
779:
778:
773:
768:
763:
758:
753:
748:
743:
738:
733:
728:
723:
718:
713:
708:
703:
698:
693:
688:
682:
680:
676:
675:
673:
672:
667:
662:
657:
652:
647:
642:
637:
632:
627:
622:
617:
612:
607:
601:
599:
595:
594:
584:
583:
580:
579:
576:
575:
572:
571:
564:
558:
557:
554:
553:
545:
544:
541:
540:
538:
537:
533:
529:
525:
521:
517:
513:
509:
505:
501:
497:
494:
493:
482:
479:
478:
476:
475:
471:
467:
463:
459:
455:
451:
447:
443:
439:
435:
432:
431:
419:
418:
410:
399:
393:
392:
389:RNA expression
381:
380:
377:
376:
368:
364:
363:
355:
352:
347:
341:
340:
331:
324:
318:
314:
313:
308:
302:
301:
293:
292:
280:
279:
276:
275:
267:
263:
262:
254:
251:
246:
240:
239:
230:
223:
217:
213:
212:
205:
199:
198:
190:
189:
177:
176:
133:
129:
128:
120:
112:
111:
107:
106:
103:
102:
99:
98:
80:
79:
71:
70:
59:
53:
52:
44:
43:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
4935:
4924:
4921:
4919:
4916:
4914:
4911:
4910:
4908:
4897:
4892:
4890:
4885:
4883:
4878:
4877:
4871:
4869:
4865:
4861:
4857:
4852:
4849:
4845:
4840:
4834:
4829:
4824:
4820:
4806:
4802:
4801:
4796:
4793:
4789:
4788:
4783:
4780:
4776:
4775:
4770:
4767:
4763:
4762:
4757:
4754:
4750:
4749:
4744:
4741:
4737:
4736:
4731:
4728:
4724:
4723:
4718:
4717:
4715:
4711:
4705:
4702:
4700:
4697:
4695:
4692:
4690:
4687:
4685:
4682:
4681:
4679:
4675:
4669:
4666:
4664:
4663:Enzyme family
4661:
4659:
4656:
4654:
4651:
4650:
4648:
4644:
4638:
4635:
4633:
4630:
4628:
4627:Cooperativity
4625:
4623:
4620:
4619:
4617:
4613:
4607:
4604:
4602:
4599:
4597:
4594:
4592:
4589:
4587:
4586:Oxyanion hole
4584:
4582:
4579:
4577:
4574:
4572:
4569:
4568:
4566:
4562:
4558:
4551:
4546:
4544:
4539:
4537:
4532:
4531:
4528:
4508:
4505:
4503:
4500:
4498:
4495:
4493:
4490:
4488:
4485:
4483:
4480:
4478:
4475:
4474:
4472:
4470:
4466:
4462:
4457:
4452:
4448:
4434:
4431:
4429:
4426:
4424:
4421:
4419:
4416:
4414:
4411:
4409:
4406:
4404:
4401:
4397:
4394:
4392:
4389:
4387:
4384:
4382:
4379:
4378:
4377:
4374:
4373:
4371:
4368:
4364:
4357:
4356:
4354:
4351:
4347:
4340:
4339:
4337:
4334:
4330:
4323:
4322:
4320:
4317:
4313:
4307:
4304:
4302:
4299:
4297:
4294:
4293:
4291:
4288:
4284:
4278:
4275:
4273:
4270:
4266:
4263:
4261:
4258:
4256:
4253:
4251:
4248:
4246:
4243:
4241:
4238:
4236:
4233:
4232:
4231:
4228:
4224:
4221:
4219:
4216:
4214:
4211:
4209:
4206:
4205:
4204:
4201:
4197:
4194:
4192:
4189:
4187:
4184:
4182:
4179:
4177:
4174:
4172:
4169:
4167:
4164:
4162:
4159:
4158:
4157:
4154:
4153:
4151:
4148:
4144:
4136:
4133:
4131:
4128:
4126:
4123:
4122:
4121:
4118:
4114:
4111:
4109:
4106:
4104:
4101:
4100:
4099:
4096:
4092:
4089:
4087:
4084:
4082:
4079:
4077:
4074:
4072:
4069:
4067:
4064:
4062:
4059:
4058:
4057:
4054:
4053:
4051:
4048:
4044:
4038:
4035:
4033:
4030:
4028:
4025:
4023:
4020:
4018:
4015:
4013:
4010:
4008:
4005:
4003:
4000:
3998:
3995:
3994:
3992:
3989:
3985:
3979:
3976:
3974:
3971:
3969:
3966:
3964:
3961:
3959:
3956:
3954:
3951:
3949:
3946:
3944:
3941:
3939:
3936:
3934:
3931:
3929:
3926:
3924:
3921:
3919:
3916:
3914:
3911:
3909:
3906:
3904:
3901:
3899:
3896:
3894:
3891:
3889:
3886:
3885:
3883:
3880:
3876:
3870:
3867:
3865:
3862:
3860:
3857:
3855:
3852:
3851:
3849:
3846:
3842:
3838:
3833:
3828:
3824:
3810:
3807:
3805:
3802:
3800:
3797:
3795:
3792:
3791:
3789:
3786:
3782:
3776:
3773:
3771:
3768:
3767:
3765:
3762:
3758:
3752:
3749:
3747:
3744:
3742:
3739:
3737:
3734:
3732:
3729:
3728:
3726:
3723:
3719:
3713:
3710:
3708:
3705:
3703:
3700:
3698:
3695:
3694:
3692:
3689:
3685:
3679:
3676:
3674:
3671:
3669:
3666:
3664:
3661:
3659:
3656:
3654:
3651:
3649:
3646:
3644:
3641:
3639:
3636:
3634:
3631:
3629:
3626:
3624:
3621:
3619:
3616:
3614:
3611:
3609:
3606:
3604:
3601:
3599:
3596:
3594:
3591:
3589:
3586:
3584:
3581:
3579:
3576:
3574:
3571:
3569:
3566:
3564:
3561:
3559:
3556:
3554:
3551:
3549:
3546:
3544:
3541:
3539:
3536:
3534:
3531:
3529:
3526:
3524:
3521:
3519:
3516:
3514:
3511:
3509:
3506:
3504:
3501:
3499:
3496:
3494:
3491:
3489:
3486:
3484:
3481:
3479:
3476:
3474:
3471:
3469:
3466:
3464:
3461:
3459:
3456:
3454:
3451:
3449:
3446:
3444:
3441:
3439:
3436:
3434:
3431:
3429:
3426:
3424:
3421:
3419:
3416:
3414:
3411:
3409:
3406:
3404:
3401:
3400:
3398:
3395:
3391:
3385:
3382:
3380:
3377:
3375:
3372:
3371:
3369:
3366:
3362:
3356:
3353:
3351:
3348:
3347:
3345:
3342:
3338:
3332:
3329:
3328:
3326:
3323:
3319:
3313:
3310:
3308:
3305:
3303:
3300:
3298:
3295:
3293:
3290:
3288:
3285:
3283:
3280:
3278:
3275:
3273:
3270:
3268:
3265:
3263:
3260:
3258:
3255:
3253:
3250:
3249:
3247:
3244:
3240:
3234:
3231:
3229:
3226:
3225:
3223:
3220:
3216:
3210:
3207:
3205:
3202:
3200:
3197:
3195:
3192:
3190:
3187:
3186:
3184:
3181:
3177:
3171:
3168:
3166:
3163:
3161:
3158:
3156:
3153:
3151:
3148:
3146:
3143:
3142:
3140:
3137:
3133:
3126:
3125:
3123:
3121:(EC 2.7.11.9)
3120:
3116:
3110:
3107:
3105:
3102:
3101:
3099:
3097:(EC 2.7.11.8)
3096:
3092:
3084:
3081:
3079:
3076:
3074:
3071:
3070:
3069:
3068:Aurora kinase
3066:
3065:
3063:
3061:(EC 2.7.11.7)
3060:
3056:
3050:
3047:
3046:
3044:
3042:(EC 2.7.11.6)
3041:
3037:
3031:
3028:
3026:
3023:
3021:
3018:
3016:
3013:
3012:
3010:
3008:(EC 2.7.11.5)
3007:
3003:
2997:
2994:
2992:
2989:
2987:
2984:
2983:
2981:
2979:(EC 2.7.11.4)
2978:
2974:
2966:
2963:
2961:
2958:
2956:
2953:
2952:
2950:
2946:
2943:
2941:
2938:
2937:
2935:
2931:
2928:
2926:
2923:
2922:
2920:
2917:
2916:
2914:
2912:(EC 2.7.11.3)
2911:
2907:
2901:
2898:
2896:
2893:
2891:
2888:
2886:
2883:
2882:
2880:
2878:(EC 2.7.11.2)
2877:
2873:
2865:
2862:
2861:
2860:
2857:
2853:
2850:
2848:
2845:
2843:
2840:
2838:
2835:
2834:
2833:
2832:EIF-2 kinases
2830:
2828:
2825:
2823:
2820:
2816:
2813:
2811:
2808:
2806:
2803:
2802:
2801:
2798:
2796:
2793:
2791:
2788:
2786:
2783:
2781:
2778:
2776:
2773:
2771:
2768:
2766:
2763:
2761:
2758:
2756:
2753:
2751:
2748:
2746:
2743:
2742:
2740:
2738:(EC 2.7.11.1)
2737:
2733:
2729:
2724:
2719:
2715:
2710:
2706:
2702:
2695:
2690:
2688:
2683:
2681:
2676:
2675:
2672:
2658:
2652:
2647:
2643:
2634:
2629:
2627:
2622:
2620:
2615:
2614:
2611:
2604:
2600:
2599:
2594:
2593:
2588:
2587:
2583:
2576:
2572:
2567:
2562:
2558:
2554:
2550:
2545:
2541:
2537:
2533:
2529:
2524:
2519:
2515:
2511:
2507:
2502:
2498:
2494:
2490:
2486:
2481:
2476:
2472:
2468:
2464:
2459:
2455:
2451:
2446:
2441:
2437:
2433:
2429:
2425:
2421:
2416:
2412:
2408:
2403:
2398:
2394:
2390:
2386:
2381:
2377:
2373:
2369:
2365:
2362:(2): 426–34.
2361:
2357:
2351:
2347:
2343:
2339:
2335:
2330:
2325:
2321:
2317:
2313:
2308:
2304:
2300:
2295:
2290:
2286:
2282:
2279:(1): 161–71.
2278:
2274:
2270:
2265:
2261:
2257:
2252:
2247:
2243:
2239:
2235:
2230:
2226:
2222:
2217:
2212:
2207:
2202:
2198:
2194:
2190:
2186:
2182:
2177:
2173:
2169:
2164:
2159:
2156:(8): 4722–9.
2155:
2151:
2147:
2142:
2138:
2134:
2130:
2126:
2122:
2118:
2112:
2108:
2104:
2099:
2094:
2090:
2086:
2082:
2077:
2073:
2069:
2064:
2059:
2055:
2051:
2048:(3): 583–93.
2047:
2043:
2039:
2034:
2030:
2026:
2022:
2018:
2014:
2010:
2006:
2002:
1998:
1994:
1989:
1985:
1981:
1976:
1971:
1967:
1963:
1959:
1954:
1950:
1946:
1942:
1938:
1933:
1929:
1925:
1921:
1917:
1913:
1909:
1904:
1900:
1896:
1892:
1888:
1884:
1880:
1877:(3): 375–80.
1876:
1872:
1867:
1866:
1861:
1852:
1848:
1844:
1840:
1835:
1830:
1826:
1822:
1818:
1811:
1808:
1803:
1799:
1794:
1789:
1785:
1781:
1777:
1773:
1769:
1762:
1759:
1754:
1750:
1745:
1740:
1736:
1732:
1729:(2): 423–33.
1728:
1724:
1720:
1716:
1709:
1706:
1701:
1697:
1692:
1687:
1682:
1677:
1673:
1669:
1665:
1663:
1654:
1651:
1646:
1640:
1637:
1632:
1628:
1623:
1618:
1613:
1608:
1604:
1600:
1596:
1592:
1588:
1581:
1578:
1573:
1569:
1564:
1559:
1555:
1551:
1547:
1540:
1537:
1532:
1528:
1522:
1519:
1514:
1510:
1504:
1501:
1497:
1493:
1488:
1486:
1484:
1480:
1476:
1472:
1467:
1465:
1463:
1459:
1452:
1447:
1444:
1441:
1438:
1435:
1432:
1431:
1430:
1428:
1420:
1418:
1416:
1412:
1408:
1403:
1402:glutamatergic
1399:
1395:
1391:
1387:
1383:
1375:
1373:
1371:
1368:
1364:
1361:
1357:
1353:
1349:
1345:
1332:
1328:
1316:
1311:
1307:
1303:
1300:
1296:
1289:
1287:
1284:
1280:
1276:
1272:
1269:
1265:
1261:
1254:
1252:
1248:
1244:
1240:
1236:
1230:
1226:
1223:
1217:
1215:
1211:
1207:
1203:
1199:
1193:
1189:
1186:
1182:
1175:
1173:
1169:
1165:
1159:
1155:
1152:
1146:
1144:
1140:
1136:
1132:
1128:
1122:
1118:
1115:
1113:RefSeq (mRNA)
1111:
1104:
1103:
1098:
1094:
1091:
1085:
1084:
1079:
1075:
1072:
1070:
1066:
1059:
1058:
1053:
1049:
1046:
1040:
1039:
1034:
1030:
1027:
1025:
1021:
1014:
1013:
1008:
1004:
1001:
995:
994:
989:
985:
982:
980:
976:
973:
970:
968:
965:
961:
958:
954:
950:
943:
939:
934:
928:
925:
923:
920:
918:
915:
913:
910:
908:
905:
903:
900:
898:
895:
893:
890:
888:
885:
883:
880:
878:
875:
873:
870:
868:
865:
863:
860:
858:
855:
853:
850:
848:
845:
843:
840:
838:
835:
833:
830:
828:
825:
823:
820:
818:
815:
813:
810:
808:
805:
803:
800:
798:
795:
793:
790:
789:
787:
784:
783:
777:
774:
772:
769:
767:
764:
762:
759:
757:
754:
752:
749:
747:
744:
742:
739:
737:
736:mitochondrion
734:
732:
729:
727:
724:
722:
719:
717:
716:cell junction
714:
712:
709:
707:
704:
702:
699:
697:
694:
692:
689:
687:
684:
683:
681:
678:
677:
671:
668:
666:
663:
661:
658:
656:
653:
651:
648:
646:
643:
641:
638:
636:
633:
631:
628:
626:
623:
621:
618:
616:
613:
611:
608:
606:
603:
602:
600:
597:
596:
593:
592:Gene ontology
589:
585:
573:
568:
565:
563:
559:
551:
546:
535:
531:
527:
523:
519:
515:
511:
507:
503:
499:
498:
495:
491:
486:
483:
473:
469:
465:
461:
457:
453:
449:
445:
441:
437:
436:
433:
429:
424:
421:
420:
417:
415:
411:
409:
408:
404:
403:
400:
398:
394:
390:
386:
382:
374:
369:
365:
361:
356:
346:
342:
335:
328:
322:
315:
307:
303:
299:
294:
290:
285:
281:
273:
268:
264:
260:
255:
245:
241:
234:
227:
221:
214:
210:
204:
200:
196:
191:
187:
182:
178:
174:
170:
166:
162:
158:
154:
150:
146:
142:
138:
130:
125:
118:
113:
108:
97:
95:
91:
87:
81:
76:
73:
72:
68:
65:
58:
54:
49:
45:
41:
36:
31:
19:
4868:expanding it
4860:chromosome 5
4853:
4838:
4800:Translocases
4797:
4784:
4771:
4758:
4745:
4735:Transferases
4732:
4719:
4576:Binding site
4007:P70S6 kinase
2656:
2597:
2591:
2556:
2552:
2513:
2509:
2470:
2466:
2427:
2423:
2392:
2388:
2359:
2355:
2319:
2315:
2276:
2272:
2241:
2237:
2188:
2184:
2153:
2149:
2120:
2116:
2088:
2084:
2045:
2041:
1996:
1992:
1965:
1961:
1943:(3): 241–7.
1940:
1936:
1911:
1907:
1874:
1870:
1824:
1820:
1810:
1775:
1771:
1761:
1726:
1722:
1708:
1671:
1667:
1661:
1653:
1639:
1594:
1590:
1580:
1556:(1): 63–70.
1553:
1550:DNA Research
1549:
1539:
1530:
1521:
1512:
1503:
1424:
1421:Interactions
1379:
1366:
1337:
1330:
1326:
1325:
1251:NP_001390241
1247:NP_001390238
1235:NP_001273738
1232:
1214:NP_001355954
1210:NP_001350919
1206:NP_001350918
1195:
1164:NM_001286809
1161:
1143:NM_001369025
1139:NM_001363990
1135:NM_001363989
1124:
1100:
1081:
1055:
1036:
1010:
991:
971:
966:
827:MAPK cascade
466:frontal pole
412:
405:
270:150,290,093
257:150,219,491
132:External IDs
83:
4571:Active site
4458:(EC 2.7.12)
3845:Polo kinase
3785:Polo kinase
2639:PDB gallery
1392:subfamily.
711:nucleoplasm
640:ATP binding
371:61,121,224
358:61,058,690
110:Identifiers
4907:Categories
4774:Isomerases
4748:Hydrolases
4615:Regulation
3136:IκB kinase
2711:2.7.11-12)
1715:Kennedy MB
1498:, May 2017
1477:, May 2017
1453:References
1354:(i.e., an
416:(ortholog)
153:HomoloGene
4918:EC 2.7.11
4858:on human
4653:EC number
3262:PKC alpha
1243:NP_803126
1239:NP_033922
1202:NP_741960
1198:NP_057065
1172:NM_177407
1168:NM_009792
1131:NM_015981
1127:NM_171825
957:Orthologs
731:cytoplasm
528:subiculum
161:GeneCards
4677:Kinetics
4601:Cofactor
4564:Activity
3618:KIAA0999
3513:MAPKAPK5
3508:MAPKAPK3
3503:MAPKAPK2
2540:16704390
2029:34818876
1949:11889801
1928:11264466
1899:31122499
1891:10851169
1851:19885326
1843:12933808
1802:12223541
1753:11160423
1700:29784083
1572:10231032
1494:–
1473:–
1427:interact
1376:Function
1363:proteins
1343:II alpha
1299:Wikidata
936:Sources:
802:G1 phase
756:dendrite
696:membrane
438:amygdala
4833:Biology
4787:Ligases
4557:Enzymes
4277:MAP3K14
4255:MAP3K11
4250:MAP3K10
4240:MAP3K13
4235:MAP3K12
4037:RPS6KC1
4032:RPS6KA1
4027:RPS6KA3
4022:RPS6KA2
4017:RPS6KB2
4002:RPS6KA4
3997:RPS6KA5
3648:Kalirin
3613:SNF1LK2
2852:EIF2AK4
2847:EIF2AK3
2701:Kinases
2575:8999860
2532:8980240
2497:8332020
2489:8940188
2454:8413226
2411:7929371
2376:7822264
2346:2039456
2338:7706316
2303:7523419
2294:2120194
2260:2394752
2225:2164678
2193:Bibcode
2172:2155236
2137:2114109
2107:1375933
2072:1374067
2063:2289443
2021:1314426
2001:Bibcode
1993:Science
1984:1309762
1793:6758084
1744:6763799
1691:5963920
1631:3475713
1599:Bibcode
1496:Ensembl
1475:Ensembl
1331:CAMKIIα
1069:UniProt
1024:Ensembl
963:Species
942:QuickGO
726:nucleus
706:synapse
691:cytosol
391:pattern
117:Aliases
18:CAMKIIα
4819:Portal
4761:Lyases
4507:MAP2K7
4502:MAP2K6
4497:MAP2K5
4492:MAP2K4
4487:MAP2K3
4482:MAP2K2
4477:MAP2K1
4428:ACVRL1
4423:ACVR2B
4418:ACVR2A
4413:ACVR1C
4408:ACVR1B
4391:BMPR1B
4386:BMPR1A
4260:MAP3K7
4245:MAP3K9
4196:MAP3K8
4191:MAP3K7
4186:MAP3K6
4181:MAP3K5
4176:MAP3K4
4171:MAP3K3
4166:MAP3K2
4161:MAP3K1
4135:MAPK14
4130:MAPK13
4125:MAPK11
4113:MAPK10
4091:MAPK15
4086:MAPK12
3978:CDC2L1
3953:CDC2L5
3628:SNF1LK
3453:CAMK2G
3448:CAMK2D
3443:CAMK2B
3438:CAMK2A
3428:CAMK1G
3423:CAMK1D
3418:CAMK1B
3413:CAMK1A
3267:PRKCB1
3204:PRKACA
3199:PRKACB
3194:PRKACG
3170:IKBKAP
2996:BCKDHB
2991:BCKDHA
2965:PRKAG3
2960:PRKAG2
2955:PRKAG1
2945:PRKAB2
2940:PRKAB1
2930:PRKAA2
2925:PRKAA1
2770:STK38L
2598:CAMK2A
2592:CAMK2A
2589:Human
2573:
2538:
2530:
2495:
2487:
2452:
2445:364685
2442:
2409:
2374:
2344:
2336:
2301:
2291:
2258:
2223:
2213:
2170:
2135:
2105:
2070:
2060:
2027:
2019:
1982:
1947:
1926:
1897:
1889:
1849:
1841:
1800:
1790:
1751:
1741:
1698:
1688:
1662:CAMK2A
1629:
1622:298983
1619:
1570:
1440:CDK5R1
1429:with:
1382:enzyme
1367:CAMK2A
1358:which
1356:enzyme
1348:CamKII
1335:a.k.a.
1285:search
1283:PubMed
1102:P11798
1083:Q9UQM7
979:Entrez
562:BioGPS
165:CAMK2A
141:114078
124:CAMK2A
33:CAMK2A
4862:is a
4713:Types
4469:MAP2K
4403:ACVR1
4396:BMPR2
4381:BMPR1
4306:GSK-3
4147:MAP3K
4108:MAPK9
4103:MAPK8
4081:MAPK7
4076:MAPK6
4071:MAPK4
4066:MAPK3
4061:MAPK1
3973:PFTK1
3968:PCTK3
3963:PCTK2
3958:PCTK1
3948:CDK12
3943:CDK10
3918:CDKL5
3898:CDKL2
3775:STK19
3770:EEF2K
3751:PHKG2
3746:PHKG1
3736:PHKA2
3731:PHKA1
3712:MYLK4
3707:MYLK3
3702:MYLK2
3678:DCLK1
3673:Titin
3663:TRIB3
3658:TRIB2
3653:TRIB1
3643:TSSK2
3623:STK40
3608:PSKH1
3603:PRKD3
3598:PRKD2
3578:PHKG2
3573:PHKG1
3563:OBSCN
3558:NUAK2
3553:NUAK1
3548:MKNK2
3543:MKNK1
3533:MARK4
3528:MARK3
3523:MARK2
3518:MARK1
3498:STK11
3493:DAPK3
3488:DAPK2
3483:DAPK1
3478:CHEK2
3473:CHEK1
3458:CAMK4
3433:CAMK2
3408:CAMK1
3403:BRSK2
3297:PRKCQ
3292:PRKCI
3287:PRKCG
3282:PRKCH
3277:PRKCE
3272:PRKCD
3233:PRKG1
3165:IKBKG
3160:IKBKE
3109:STK10
3104:FASTK
3030:IDH3G
3025:IDH3B
3020:IDH3A
2986:BCKDK
2780:ROCK1
2765:STK38
2760:MAST2
2755:MAST1
2750:LATS2
2745:LATS1
2536:S2CID
2493:S2CID
2342:S2CID
2216:54319
2025:S2CID
1895:S2CID
1847:S2CID
1668:eLife
1442:, and
1413:with
1012:12322
972:Mouse
967:Human
938:Amigo
414:Mouse
407:Human
354:Start
289:Mouse
253:Start
186:Human
157:56577
149:88256
4864:stub
4856:gene
4805:list
4798:EC7
4792:list
4785:EC6
4779:list
4772:EC5
4766:list
4759:EC4
4753:list
4746:EC3
4740:list
4733:EC2
4727:list
4720:EC1
4296:TPK1
4272:CDC7
4230:MLKs
4223:KSR2
4218:KSR1
4213:BRAF
4208:ARAF
4203:RAFs
3938:CDK9
3933:CDK8
3928:CDK7
3923:CDK6
3913:CDK5
3908:CDK4
3903:CDK3
3893:CDK2
3888:CDK1
3869:PLK4
3864:PLK3
3859:PLK2
3854:PLK1
3809:PLK4
3804:PLK3
3799:PLK2
3794:PLK1
3741:PHKB
3697:MYLK
3668:TRIO
3638:SPEG
3633:SNRK
3593:PKD1
3588:PIM2
3583:PIM1
3568:PASK
3538:MELK
3468:CASK
3463:MLCK
3384:GRK6
3379:GRK5
3374:GRK4
3312:PKN3
3307:PKN2
3209:PRKY
3155:TBK1
3150:IKK2
3145:CHUK
3049:STK4
3015:IDH2
2900:PDK4
2895:PDK3
2890:PDK2
2885:PDK1
2864:WEE1
2859:Wee1
2827:mTOR
2815:AKT3
2810:AKT2
2805:AKT1
2795:SGK3
2790:SGK2
2657:1hkx
2571:PMID
2528:PMID
2510:Cell
2485:PMID
2450:PMID
2407:PMID
2372:PMID
2334:PMID
2299:PMID
2256:PMID
2221:PMID
2168:PMID
2133:PMID
2103:PMID
2068:PMID
2017:PMID
1980:PMID
1945:PMID
1924:PMID
1887:PMID
1839:PMID
1798:PMID
1749:PMID
1696:PMID
1627:PMID
1568:PMID
1446:DLG1
1370:gene
1350:, a
397:Bgee
345:Band
306:Chr.
249:5q32
244:Band
203:Chr.
137:OMIM
94:5IG3
90:3SOA
86:2VZ6
67:RCSB
64:PDBe
4301:TTK
4265:ZAK
2842:HRI
2837:PKR
2785:SGK
2775:CIT
2561:doi
2557:272
2518:doi
2475:doi
2471:271
2440:PMC
2432:doi
2397:doi
2393:269
2364:doi
2360:116
2324:doi
2320:270
2289:PMC
2281:doi
2277:127
2246:doi
2242:265
2211:PMC
2201:doi
2158:doi
2154:265
2125:doi
2121:169
2093:doi
2089:267
2058:PMC
2050:doi
2046:117
2009:doi
1997:256
1970:doi
1966:267
1916:doi
1879:doi
1829:doi
1825:278
1788:PMC
1780:doi
1739:PMC
1731:doi
1686:PMC
1676:doi
1617:PMC
1607:doi
1558:doi
1400:at
1333:),
993:815
570:n/a
367:End
266:End
169:OMA
145:MGI
57:PDB
4909::
2951:γ
2936:β
2921:α
2709:EC
2703::
2569:.
2555:.
2551:.
2534:.
2526:.
2514:87
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1941:47
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