335:
312:
209:
234:
586:
341:
240:
42:
1280:
NT5E can act as an immune inhibitory control molecule. Free adenosine generated by NT5E inhibits cellular immune responses and thereby promotes immune escape of tumor cells. Due to enzymatic and non-enzymatic properties, CD73 is involved in cancer-related processes and is upregulated in many cancers
1166:, which can be found in c-AMP promoter parts. SMADs 2, 3, 4 and 5 and SP-1 are binding to the NT5E promoter in rats, as was proven in chromatin immunoprecipitation assays. Due to the fact, that the human and rat NT5E transcripts are 89% identical, human NT5E could be also regulated by SMAD proteins.
1235:
and function of T cell. CD73 also occurs on anergic CD4 + T cells, thereby maintaining self tolerance to healthy tissues as well as protecting the fetus from the mother's immune system during pregnancy. Also described was adenosine generated by NT5E, which limits the inflammatory immune response by
1182:
differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for
68:
1271:
and regulatory T cells also mediate their effects via adenosine generated by local ectonucleotidase. In some cases of lupus patients, adequate T cell expression of CD73 is missing, which shows an impaired regulatory function of T cells.
2483:
Thomson LF, Ruedi JM, Glass A, et al. (January 1990). "Production and characterization of monoclonal antibodies to the glycosyl phosphatidylinositol-anchored lymphocyte differentiation antigen ecto-5'-nucleotidase (CD73)".
1978:
1566:
Allard B, Cousineau I, Spring K, et al. (2019-01-01), "Chapter
Fifteen - Measurement of CD73 enzymatic activity using luminescence-based and colorimetric assays", in Galluzzi L, Rudqvist NP (eds.),
1412:. In tumor cells the miRNA expression pattern often change and therefore affect the surface NT5E, which as result interfere the anti-tumor immune response. For example, studies confirm the role of the
1174:
Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase; EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being
1178:. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of
3756:
2242:
Zhang F, Luo Y, Shao Z, et al. (April 2016). "MicroRNA-187, a downstream effector of TGFβ pathway, suppresses Smad-mediated epithelial-mesenchymal transition in colorectal cancer".
2148:
Tripathi A, Lin E, Nussenzveig R, et al. (2019-05-20). "NT5E expression and the immune landscape of prostate cancer (PC): An analysis from The Cancer Genome Atlas database".
2895:
1531:
Misumi Y, Ogata S, Ohkubo K, et al. (August 1990). "Primary structure of human placental 5'-nucleotidase and identification of the glycolipid anchor in the mature form".
348:
247:
3746:
1434:
2758:
Aumüller G, Renneberg H, Schiemann PJ, et al. (1997). "The Role of
Apocrine Released Proteins in the Post-Testicular Regulation of Human Sperm Function".
2608:
Hansen KR, Resta R, Webb CF, et al. (December 1995). "Isolation and characterization of the promoter of the human 5'-nucleotidase (CD73)-encoding gene".
3726:
2863:
839:
820:
170:
4588:
2912:
2888:
1227:. Immune suppression mediated by adenosinergic pathways is very important for maintaining immune system homeostasis. Immune suppressive functions of
2674:"Differential regulation and function of CD73, a glycosyl-phosphatidylinositol-linked 70-kD adhesion molecule, on lymphocytes and endothelial cells"
2513:
Klemens MR, Sherman WR, Holmberg NJ, et al. (November 1990). "Characterization of soluble vs membrane-bound human placental 5'-nucleotidase".
2411:
Babiychuk EB, Draeger A (June 2006). "Regulation of ecto-5'-nucleotidase activity via Ca2+-dependent, annexin 2-mediated membrane rearrangement?".
1377:
receptors associated with Gαi proteins, promoting both the migration and proliferation of tumor cells. Especially due to its beneficial effects in
4319:
1329:. This can mediate the metastatic and invasive properties of cancer. In mouse breast and prostate cancer tumor models as well as in breast cancer
4307:
4085:
1309:. It is an important key molecule in cancer regulation and development and is involved in tumor progression. In addition, NT5E functions as an
4371:
4366:
4312:
4092:
2873:
2775:
1586:
1513:
1495:
4925:
4920:
3825:
3751:
2881:
1188:
65:
4854:
4849:
4844:
4839:
3766:
1785:
1341:
and human breast cancer cells. Tumor infiltration by cells which express NT5E such as myeloid derived suppressor cells (MDSC), Treg's,
334:
1047:
4819:
1054:
1215:
which is expressed on multiple cells. This enzyme mediates the gradual hydrolysis of the autocrine and paracrine danger signals of
311:
4055:
1674:
1200:
4623:
4117:
3803:
2542:
Boyle JM, Hey Y, Guerts van Kessel A, et al. (December 1988). "Assignment of ecto-5'-nucleotidase to human chromosome 6".
1482:
1461:
2579:
Vlahović P, Stefanović V (1995). "Effect of dopamine on ecto-5'-nucleotidase expression in human glomerular mesangial cells".
1369:(NK). Thus, adenosine may inhibit the function of these immune cells. In addition, the tumor cells may also express adenosine
4262:
3798:
1346:
1163:
1936:
Ghalamfarsa G, Kazemi MH, Raoofi
Mohseni S, et al. (2019). "CD73 as a potential opportunity for cancer immunotherapy".
1478:
233:
208:
4759:
4231:
4226:
4171:
3905:
3354:
2382:
Rosi F, Carlucci F, Marinello E, et al. (March 2002). "Ecto-5'-nucleotidase in B-cell chronic lymphocytic leukemia".
1192:
1457:
4453:
4176:
150:
1252:
Some tumours have upregulation and overexpression of CD73 so it has been proposed as a drug target for cancer therapy.
3771:
2793:
Rosi F, Agostinho AB, Carlucci F, et al. (1998). "Behaviour of human lymphocytic isoenzymes of 5'-nucleotidase".
1268:
347:
246:
4483:
2908:
2050:"CD73/NT5E is a target of miR-30a-5p and plays an important role in the pathogenesis of non-small cell lung cancer"
1429:
1118:
3349:
340:
239:
4533:
3428:
2833:
1159:
884:
158:
1409:
2345:
Resta R, Yamashita Y, Thompson LF (February 1998). "Ecto-enzyme and signaling functions of lymphocyte CD73".
4497:
1175:
1133:
865:
1408:
at posttranscriptional level via binding to mRNA. This leads to degradation of the target mRNA molecule or
3840:
3835:
3830:
3820:
3127:
3055:
2312:"Cell-to-cell transfer of glycosylphosphatidylinositol-anchored membrane proteins during sperm maturation"
1216:
3184:
3102:
1378:
1374:
1370:
1220:
1149:
1330:
4421:
4134:
2717:"Surface expression, polarization, and functional significance of CD73 in human intestinal epithelia"
1568:
1366:
1318:
222:
1907:
1338:
137:
4448:
4267:
1921:
1358:
1005:
958:
1413:
1231:
are also dependent on CD73 expression. Treg's generally suppress the immune response. They affect
3855:
3589:
2829:
2567:
2436:
2370:
2173:
1961:
1600:
1314:
1241:
1232:
182:
1417:
1030:
1009:
979:
954:
1382:
2840:
2810:
2781:
2771:
2746:
2703:
2660:
2625:
2596:
2559:
2530:
2501:
2471:
2428:
2399:
2362:
2333:
2298:
2259:
2224:
2165:
2130:
2081:
2025:
1953:
1890:
1832:
1768:
1719:
1656:
1592:
1582:
1548:
1228:
130:
58:
1859:"Controlling the Immune Suppressor: Transcription Factors and MicroRNAs Regulating CD73/NT5E"
1625:"Controlling the Immune Suppressor: Transcription Factors and MicroRNAs Regulating CD73/NT5E"
4628:
4361:
4282:
3845:
3038:
2964:
2802:
2763:
2736:
2728:
2693:
2685:
2650:
2617:
2588:
2551:
2522:
2493:
2461:
2420:
2391:
2354:
2323:
2290:
2251:
2214:
2204:
2157:
2120:
2112:
2071:
2061:
2015:
2005:
1945:
1880:
1870:
1822:
1814:
1758:
1750:
1709:
1701:
1646:
1636:
1574:
1540:
1386:
1184:
427:
358:
302:
257:
1152:
4688:
3224:
3219:
3142:
1405:
1342:
585:
402:
178:
2161:
4473:
3895:
3406:
3209:
2698:
2673:
2497:
2358:
2219:
2192:
2125:
2100:
2076:
2049:
2020:
1993:
1885:
1858:
1827:
1802:
1763:
1738:
1714:
1689:
1651:
1624:
1544:
1256:
1196:
1183:
divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. Rare
1155:
2806:
2741:
2716:
2466:
2449:
2395:
2294:
1994:"Ectonucleotidase-Mediated Suppression of Lupus Autoimmunity and Vascular Dysfunction"
754:
749:
744:
739:
734:
729:
724:
719:
714:
709:
693:
688:
683:
678:
673:
668:
663:
647:
642:
637:
632:
627:
4914:
4443:
3900:
2991:
2867:
2849:
2621:
2526:
2177:
1604:
1306:
614:
2571:
2374:
1965:
1203:
reducing circulation in the legs and the joints of the hands and feet causing pain.
4799:
4107:
4097:
3628:
3594:
2440:
1354:
1334:
1286:
420:
199:
2762:. Advances in Experimental Medicine and Biology. Vol. 424. pp. 193–219.
2655:
2638:
1949:
162:
2767:
2255:
186:
4809:
4458:
4236:
4211:
3910:
3532:
3458:
2932:
1518:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1500:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1362:
1322:
1294:
1237:
2116:
1578:
503:
4739:
4463:
4144:
3885:
3761:
3394:
3389:
3384:
3239:
3023:
2592:
2066:
1818:
1179:
319:
216:
166:
2328:
2311:
2209:
2169:
2010:
1875:
1641:
4578:
4573:
4568:
4558:
4553:
4548:
4543:
1397:
1385:
therapy is now a promising approach to cancer treatment in the future. CD73
1224:
1137:
784:
563:
441:
386:
373:
285:
272:
174:
2432:
2403:
2263:
2228:
2134:
2085:
2029:
1957:
1894:
1836:
1772:
1723:
1660:
1596:
2814:
2785:
2750:
2707:
2689:
2664:
2629:
2600:
2563:
2534:
2505:
2366:
2337:
2302:
1705:
1573:, Methods in Enzymology, vol. 629, Academic Press, pp. 269–289,
1552:
1094:
1089:
4884:
4784:
4598:
4583:
3786:
3781:
3689:
3379:
2475:
1310:
1298:
1290:
1282:
1078:
929:
910:
2281:
Resta R, Thompson LF (February 1997). "T cell signalling through CD73".
1980:
Anti-CD73 antibody agent appears safe, shows promise in advanced cancers
1754:
1389:
are currently being tested in clinical trials for the cancer treatment.
4834:
4829:
4824:
4724:
4538:
4528:
4355:
4334:
4329:
4297:
4102:
4022:
4017:
4012:
4007:
4002:
3920:
3613:
3453:
3448:
3443:
3438:
3433:
2904:
2854:
2844:
2581:
2555:
2424:
1350:
1326:
1302:
896:
851:
2732:
1337:. His expression promotes invasion and metastasis of murine and human
107:
103:
99:
95:
91:
87:
41:
4774:
4734:
4719:
4703:
4698:
4678:
4673:
4608:
4416:
4386:
4350:
4341:
4154:
4122:
3986:
3981:
3951:
3930:
3890:
3850:
3716:
3694:
3653:
3577:
3572:
3567:
3562:
3557:
3552:
3421:
3416:
3411:
3359:
3344:
3214:
3204:
3167:
3162:
3080:
3075:
1212:
1122:
1062:
806:
1852:
1850:
1848:
1846:
1688:
St
Hilaire C, Ziegler SG, Markello TC, et al. (February 2011).
141:, CALJA, CD73, E5NT, NT, NT5, NTE, eN, eNT, 5'-nucleotidase ecto
17:
4899:
4874:
4794:
4789:
4779:
4769:
4754:
4749:
4744:
4729:
4683:
4668:
4633:
4618:
4613:
4603:
4523:
4518:
4513:
4492:
4488:
4478:
4391:
4292:
4287:
4246:
4196:
4191:
4186:
4181:
4166:
4159:
4139:
4127:
4070:
4065:
4060:
4050:
4045:
4038:
3976:
3966:
3961:
3956:
3946:
3925:
3915:
3880:
3875:
3870:
3865:
3860:
3815:
3810:
3776:
3741:
3736:
3731:
3721:
3709:
3704:
3684:
3679:
3674:
3669:
3623:
3515:
3510:
3329:
3313:
3306:
3301:
3296:
3291:
3286:
3281:
3256:
3234:
3229:
3122:
3048:
3043:
3033:
2639:"CD73 mediates adhesion of B cells to follicular dendritic cells"
2193:"Editorial: Immune Checkpoint Molecules and Cancer Immunotherapy"
769:
765:
4894:
4889:
4879:
4869:
4864:
4859:
4814:
4804:
4764:
4693:
4663:
4658:
4653:
4648:
4643:
4638:
4593:
4563:
4468:
4436:
4431:
4411:
4401:
4396:
4381:
4376:
4277:
4272:
4241:
4221:
4216:
4206:
4201:
4080:
4033:
3993:
3648:
3643:
3638:
3633:
3618:
3609:
3604:
3599:
3584:
3542:
3537:
3527:
3522:
3505:
3500:
3495:
3485:
3480:
3475:
3470:
3465:
3401:
3374:
3369:
3364:
3339:
3334:
3271:
3266:
3261:
3251:
3246:
3199:
3194:
3189:
3179:
3174:
3157:
3152:
3147:
3137:
3132:
3117:
3112:
3107:
3097:
3092:
3087:
3070:
3065:
3060:
3011:
2979:
2974:
2969:
2952:
2947:
2942:
2937:
2715:
Strohmeier GR, Lencer WI, Patapoff TW, et al. (June 1997).
1803:"The role of adenosinergic pathway in human autoimmune diseases"
1789:
1129:
154:
2877:
2101:"2B-mediated feedforward circuit enforces an immune checkpoint"
594:
4406:
3018:
3006:
3001:
2996:
2986:
2959:
2927:
1923:
1401:
2450:"Ecto-5'-nucleotidase of intact cultured C6 rat glioma cells"
2839:
Overview of all the structural information available in the
2672:
Airas L, Niemelä J, Salmi M, et al. (January 1997).
410:
1992:
Knight JS, Mazza LF, Yalavarthi S, et al. (2018).
1345:(DC) leads to accumulation of adenosine. Subsequently,
1739:"Heredo-familial vascular and articular calcification"
1570:
Tumor
Immunology and Immunotherapy – Molecular Methods
1255:
An anti-CD73 antibody CPI-006 has started early stage
575:
4712:
4506:
4255:
3939:
3662:
3322:
2920:
2515:
1023:
998:
972:
947:
2099:Yu M, Guo G, Huang L, et al. (January 2020).
2048:Zhu J, Zeng Y, Li W, et al. (February 2017).
1474:
1472:
1470:
1453:
1451:
1449:
2448:Stefanovic V, Mandel P, Rosenberg A (July 1976).
357:
256:
1675:"Entrez Gene: NT5E 5′-nucleotidase, ecto (CD73)"
1857:Kordaß T, Osen W, Eichmüller SB (2018-04-18).
1479:GRCm38: Ensembl release 89: ENSMUSG00000032420
1187:are associated with a syndrome of adult-onset
2889:
1435:Arterial calcification due to CD73 deficiency
8:
1909:Targeting adenosine for cancer immunotherapy
1690:"NT5E mutations and arterial calcifications"
715:negative regulation of inflammatory response
2191:Bazhin AV, Amedei A, Karakhanova S (2018).
1458:GRCh38: Ensembl release 89: ENSG00000135318
1420:expression, NT5E expression was decreased.
2896:
2882:
2874:
2864:United States National Library of Medicine
1801:Dong K, Gao ZW, Zhang HZ (December 2016).
780:
610:
398:
297:
194:
76:
2913:list of human clusters of differentiation
2832:at the U.S. National Library of Medicine
2740:
2697:
2654:
2465:
2327:
2218:
2208:
2124:
2075:
2065:
2019:
2009:
1884:
1874:
1826:
1762:
1713:
1650:
1640:
1317:and can regulate cellular signaling with
638:hydrolase activity, acting on ester bonds
2862:This article incorporates text from the
1623:Kordaß T, Osen W, Eichmüller SB (2018).
2043:
2041:
2039:
1445:
710:pyrimidine nucleoside catabolic process
2637:Airas L, Jalkanen S (September 1996).
1333:, NT5E was confirmed to support tumor
31:
2721:The Journal of Clinical Investigation
1259:as a treatment for advanced cancers.
362:
323:
318:
261:
220:
215:
7:
1189:calcification of joints and arteries
2454:The Journal of Biological Chemistry
2162:10.1200/JCO.2019.37.15_suppl.e16591
1786:Online Mendelian Inheritance in Man
1694:The New England Journal of Medicine
720:purine nucleotide catabolic process
2498:10.1111/j.1399-0039.1990.tb01750.x
2359:10.1111/j.1600-065X.1998.tb01574.x
2310:Kirchhoff C, Hale G (March 1996).
1545:10.1111/j.1432-1033.1990.tb19158.x
1144:Transcription factor binding sites
1132:. CD73 commonly serves to convert
1020:
995:
969:
944:
920:
901:
875:
856:
830:
811:
580:
498:
436:
415:
27:Enzyme converting AMP to adenosine
25:
2384:Biomedicine & Pharmacotherapy
1267:Specialized immune cells such as
1125:that in humans is encoded by the
2413:Biochemical Society Transactions
1743:Annals of the Rheumatic Diseases
1533:European Journal of Biochemistry
1269:myeloid-derived suppressor cells
1148:NT5E contains binding sites for
584:
346:
339:
333:
310:
245:
238:
232:
207:
40:
2760:The Fate of the Male Germ Cell
730:adenosine biosynthetic process
664:anchored component of membrane
595:More reference expression data
564:More reference expression data
1:
2807:10.1016/S0024-3205(98)00206-9
2656:10.1182/blood.V88.5.1755.1755
2467:10.1016/S0021-9258(17)33333-1
2396:10.1016/S0753-3322(01)00072-5
2295:10.1016/S0898-6568(96)00132-5
1950:10.1080/14728222.2019.1559829
331:
230:
2768:10.1007/978-1-4615-5913-9_39
2622:10.1016/0378-1119(95)00574-9
2527:10.1016/0006-291X(90)91601-N
2316:Molecular Human Reproduction
2256:10.1016/j.canlet.2016.01.037
2150:Journal of Clinical Oncology
1263:Systemic lupus erythematosus
750:nucleotide catabolic process
745:leukocyte cell-cell adhesion
4926:Clusters of differentiation
4921:Genes on human chromosome 6
2909:clusters of differentiation
2678:The Journal of Cell Biology
1353:that express the adenosine
1162:and elements responsive to
452:stromal cell of endometrium
4942:
2117:10.1038/s41467-019-14060-x
1579:10.1016/bs.mie.2019.10.007
1430:Cluster of differentiation
1349:signaling is triggered in
1119:cluster of differentiation
542:retinal pigment epithelium
2853:(5′-nucleotidase) at the
2593:10.3109/13813459409007533
2067:10.1186/s12943-017-0591-1
1819:10.1007/s12026-016-8870-2
1514:"Mouse PubMed Reference:"
1496:"Human PubMed Reference:"
1416:in NT5E regulation. Upon
1404:molecules which regulate
1211:NT5E (CD73) is a surface
1093:
1088:
1084:
1077:
1061:
1042:
1027:
1002:
991:
976:
951:
940:
927:
923:
908:
904:
895:
882:
878:
863:
859:
850:
837:
833:
818:
814:
805:
790:
783:
779:
763:
613:
609:
592:
583:
574:
561:
510:
501:
448:
439:
409:
401:
397:
380:
367:
330:
309:
300:
296:
279:
266:
229:
206:
197:
193:
148:
145:
135:
128:
123:
84:
79:
62:
57:
52:
48:
39:
34:
2834:Medical Subject Headings
2210:10.3389/fimmu.2018.02878
2011:10.3389/fimmu.2018.01322
1938:Expert Opin Ther Targets
1876:10.3389/fimmu.2018.00813
1642:10.3389/fimmu.2018.00813
1410:translational repression
648:5'-nucleotidase activity
480:tendon of biceps brachii
2197:Frontiers in Immunology
1998:Frontiers in Immunology
1863:Frontiers in Immunology
1629:Frontiers in Immunology
1109:(5′-NT), also known as
1055:Chr 9: 88.21 – 88.25 Mb
2329:10.1093/molehr/2.3.177
1737:Sharp J (March 1954).
1361:are also expressed on
1191:(CALJA) affecting the
1048:Chr 6: 85.45 – 85.5 Mb
538:neural layer of retina
518:lumbar spinal ganglion
2690:10.1083/jcb.136.2.421
2347:Immunological Reviews
2105:Nature Communications
1706:10.1056/NEJMoa0912923
1400:are small non-coding
1236:negative feedback in
1223:to anti-inflammatory
1150:transcription factors
755:NAD metabolic process
740:DNA metabolic process
725:AMP catabolic process
669:extracellular exosome
514:epithelium of stomach
2156:(15_suppl): e16591.
1807:Immunologic Research
1319:extracellular matrix
1111:ecto-5′-nucleotidase
550:skin of external ear
472:smooth muscle tissue
325:Chromosome 9 (mouse)
223:Chromosome 6 (human)
80:List of PDB id codes
53:Available structures
2830:NT5E+protein,+human
2283:Cellular Signalling
1755:10.1136/ard.13.1.15
1367:natural killer cell
1321:components such as
484:germinal epithelium
476:canal of the cervix
2866:, which is in the
2556:10.1007/BF00283737
2425:10.1042/BST0340374
1813:(5–6): 1133–1141.
1359:Adenosine receptor
1315:signaling molecule
1242:adenosine receptor
1240:which express the
1229:T regulatory cells
885:ENSMUSG00000032420
703:Biological process
657:Cellular component
643:hydrolase activity
633:nucleotide binding
621:Molecular function
4908:
4907:
2777:978-1-4613-7711-5
2733:10.1172/JCI119447
1588:978-0-12-818671-8
1379:mouse tumor model
1207:Immunosuppression
1104:
1103:
1100:
1099:
1073:
1072:
1038:
1037:
1017:
1016:
987:
986:
966:
965:
936:
935:
917:
916:
891:
890:
872:
871:
846:
845:
827:
826:
775:
774:
735:dephosphorylation
628:metal ion binding
605:
604:
601:
600:
570:
569:
557:
556:
495:
494:
393:
392:
292:
291:
119:
118:
115:
114:
63:Ortholog search:
16:(Redirected from
4933:
2898:
2891:
2884:
2875:
2818:
2789:
2754:
2744:
2727:(11): 2588–601.
2711:
2701:
2668:
2658:
2633:
2604:
2575:
2538:
2509:
2479:
2469:
2444:
2407:
2378:
2341:
2331:
2306:
2268:
2267:
2239:
2233:
2232:
2222:
2212:
2188:
2182:
2181:
2145:
2139:
2138:
2128:
2096:
2090:
2089:
2079:
2069:
2054:Molecular Cancer
2045:
2034:
2033:
2023:
2013:
1989:
1983:
1976:
1970:
1969:
1933:
1927:
1919:
1913:
1905:
1899:
1898:
1888:
1878:
1854:
1841:
1840:
1830:
1798:
1792:
1783:
1777:
1776:
1766:
1734:
1728:
1727:
1717:
1685:
1679:
1678:
1671:
1665:
1664:
1654:
1644:
1620:
1614:
1613:
1612:
1611:
1563:
1557:
1556:
1528:
1522:
1521:
1510:
1504:
1503:
1492:
1486:
1476:
1465:
1455:
1365:, DCs, MDSC and
1248:As a drug target
1185:allelic variants
1086:
1085:
1057:
1050:
1033:
1021:
1012:
996:
992:RefSeq (protein)
982:
970:
961:
945:
921:
902:
876:
857:
831:
812:
781:
611:
597:
588:
581:
566:
530:seminal vesicula
506:
504:Top expressed in
499:
468:cartilage tissue
444:
442:Top expressed in
437:
416:
399:
389:
376:
365:
350:
343:
337:
326:
314:
298:
288:
275:
264:
249:
242:
236:
225:
211:
195:
189:
187:NT5E - orthologs
140:
133:
110:
77:
71:
50:
49:
44:
32:
21:
4941:
4940:
4936:
4935:
4934:
4932:
4931:
4930:
4911:
4910:
4909:
4904:
4708:
4502:
4251:
3935:
3658:
3318:
2916:
2902:
2826:
2821:
2801:(25): 2257–66.
2792:
2778:
2757:
2714:
2671:
2636:
2616:(1–2): 307–12.
2607:
2578:
2541:
2512:
2486:Tissue Antigens
2482:
2447:
2419:(Pt 3): 374–6.
2410:
2381:
2344:
2309:
2280:
2276:
2274:Further reading
2271:
2241:
2240:
2236:
2190:
2189:
2185:
2147:
2146:
2142:
2098:
2097:
2093:
2047:
2046:
2037:
1991:
1990:
1986:
1977:
1973:
1935:
1934:
1930:
1920:
1916:
1906:
1902:
1856:
1855:
1844:
1800:
1799:
1795:
1784:
1780:
1736:
1735:
1731:
1687:
1686:
1682:
1673:
1672:
1668:
1622:
1621:
1617:
1609:
1607:
1589:
1565:
1564:
1560:
1530:
1529:
1525:
1512:
1511:
1507:
1494:
1493:
1489:
1477:
1468:
1456:
1447:
1443:
1426:
1406:gene expression
1395:
1343:dendritic cells
1331:xenograft model
1278:
1265:
1257:clinical trials
1250:
1209:
1201:tibial arteries
1172:
1146:
1107:5′-nucleotidase
1095:View/Edit Mouse
1090:View/Edit Human
1053:
1046:
1043:Location (UCSC)
1029:
1008:
1004:
978:
957:
953:
866:ENSG00000135318
759:
698:
679:plasma membrane
652:
593:
562:
553:
548:
546:proximal tubule
544:
540:
536:
532:
528:
524:
520:
516:
502:
491:
486:
482:
478:
474:
470:
466:
462:
458:
456:Achilles tendon
454:
440:
384:
371:
363:
353:
352:
351:
344:
324:
301:Gene location (
283:
270:
262:
252:
251:
250:
243:
221:
198:Gene location (
149:
136:
129:
86:
64:
28:
23:
22:
15:
12:
11:
5:
4939:
4937:
4929:
4928:
4923:
4913:
4912:
4906:
4905:
4903:
4902:
4897:
4892:
4887:
4882:
4877:
4872:
4867:
4862:
4857:
4852:
4847:
4842:
4837:
4832:
4827:
4822:
4817:
4812:
4807:
4802:
4797:
4792:
4787:
4782:
4777:
4772:
4767:
4762:
4757:
4752:
4747:
4742:
4737:
4732:
4727:
4722:
4716:
4714:
4710:
4709:
4707:
4706:
4701:
4696:
4691:
4686:
4681:
4676:
4671:
4666:
4661:
4656:
4651:
4646:
4641:
4636:
4631:
4626:
4621:
4616:
4611:
4606:
4601:
4596:
4591:
4586:
4581:
4576:
4571:
4566:
4561:
4556:
4551:
4546:
4541:
4536:
4531:
4526:
4521:
4516:
4510:
4508:
4504:
4503:
4501:
4500:
4495:
4486:
4481:
4476:
4471:
4466:
4461:
4456:
4451:
4446:
4441:
4440:
4439:
4434:
4424:
4419:
4414:
4409:
4404:
4399:
4394:
4389:
4384:
4379:
4374:
4369:
4364:
4359:
4353:
4344:
4339:
4338:
4337:
4332:
4322:
4317:
4316:
4315:
4310:
4300:
4295:
4290:
4285:
4280:
4275:
4270:
4265:
4259:
4257:
4253:
4252:
4250:
4249:
4244:
4239:
4234:
4229:
4224:
4219:
4214:
4209:
4204:
4199:
4194:
4189:
4184:
4179:
4174:
4169:
4164:
4163:
4162:
4157:
4147:
4142:
4137:
4132:
4131:
4130:
4125:
4120:
4110:
4105:
4100:
4095:
4090:
4089:
4088:
4083:
4073:
4068:
4063:
4058:
4053:
4048:
4043:
4042:
4041:
4036:
4026:
4020:
4015:
4010:
4005:
3996:
3991:
3990:
3989:
3984:
3979:
3969:
3964:
3959:
3954:
3949:
3943:
3941:
3937:
3936:
3934:
3933:
3928:
3923:
3918:
3913:
3908:
3903:
3898:
3893:
3888:
3883:
3878:
3873:
3868:
3863:
3858:
3853:
3848:
3843:
3838:
3833:
3828:
3823:
3818:
3813:
3808:
3807:
3806:
3801:
3791:
3790:
3789:
3784:
3774:
3769:
3764:
3759:
3754:
3749:
3744:
3739:
3734:
3729:
3724:
3719:
3714:
3713:
3712:
3707:
3697:
3692:
3687:
3682:
3677:
3672:
3666:
3664:
3660:
3659:
3657:
3656:
3651:
3646:
3641:
3636:
3631:
3626:
3621:
3616:
3607:
3602:
3597:
3592:
3587:
3582:
3581:
3580:
3575:
3570:
3565:
3560:
3555:
3545:
3540:
3535:
3530:
3525:
3520:
3519:
3518:
3513:
3503:
3498:
3493:
3488:
3483:
3478:
3473:
3468:
3463:
3462:
3461:
3456:
3451:
3446:
3441:
3436:
3426:
3425:
3424:
3419:
3414:
3404:
3399:
3398:
3397:
3392:
3387:
3377:
3372:
3367:
3362:
3357:
3352:
3347:
3342:
3337:
3332:
3326:
3324:
3320:
3319:
3317:
3316:
3311:
3310:
3309:
3304:
3299:
3294:
3289:
3284:
3274:
3269:
3264:
3259:
3254:
3249:
3244:
3243:
3242:
3237:
3232:
3227:
3217:
3212:
3207:
3202:
3197:
3192:
3187:
3182:
3177:
3172:
3171:
3170:
3165:
3155:
3150:
3145:
3140:
3135:
3130:
3125:
3120:
3115:
3110:
3105:
3100:
3095:
3090:
3085:
3084:
3083:
3078:
3068:
3063:
3058:
3053:
3052:
3051:
3046:
3041:
3036:
3026:
3021:
3016:
3015:
3014:
3004:
2999:
2994:
2989:
2984:
2983:
2982:
2977:
2972:
2962:
2957:
2956:
2955:
2950:
2945:
2940:
2935:
2924:
2922:
2918:
2917:
2903:
2901:
2900:
2893:
2886:
2878:
2859:
2858:
2837:
2825:
2824:External links
2822:
2820:
2819:
2790:
2776:
2755:
2712:
2669:
2649:(5): 1755–64.
2634:
2605:
2576:
2544:Human Genetics
2539:
2510:
2480:
2460:(13): 3900–5.
2445:
2408:
2379:
2342:
2307:
2277:
2275:
2272:
2270:
2269:
2244:Cancer Letters
2234:
2183:
2140:
2091:
2035:
1984:
1971:
1944:(2): 127–142.
1928:
1914:
1900:
1842:
1793:
1778:
1729:
1680:
1666:
1615:
1587:
1558:
1523:
1505:
1487:
1466:
1444:
1442:
1439:
1438:
1437:
1432:
1425:
1422:
1394:
1391:
1339:melanoma cells
1277:
1274:
1264:
1261:
1249:
1246:
1208:
1205:
1171:
1168:
1145:
1142:
1102:
1101:
1098:
1097:
1092:
1082:
1081:
1075:
1074:
1071:
1070:
1068:
1066:
1059:
1058:
1051:
1044:
1040:
1039:
1036:
1035:
1025:
1024:
1018:
1015:
1014:
1000:
999:
993:
989:
988:
985:
984:
974:
973:
967:
964:
963:
949:
948:
942:
938:
937:
934:
933:
925:
924:
918:
915:
914:
906:
905:
899:
893:
892:
889:
888:
880:
879:
873:
870:
869:
861:
860:
854:
848:
847:
844:
843:
835:
834:
828:
825:
824:
816:
815:
809:
803:
802:
797:
792:
788:
787:
777:
776:
773:
772:
761:
760:
758:
757:
752:
747:
742:
737:
732:
727:
722:
717:
712:
706:
704:
700:
699:
697:
696:
691:
686:
681:
676:
671:
666:
660:
658:
654:
653:
651:
650:
645:
640:
635:
630:
624:
622:
618:
617:
607:
606:
603:
602:
599:
598:
590:
589:
578:
572:
571:
568:
567:
559:
558:
555:
554:
552:
551:
547:
543:
539:
535:
531:
527:
523:
519:
515:
511:
508:
507:
496:
493:
492:
490:
489:
485:
481:
477:
473:
469:
465:
464:synovial joint
461:
460:jejunal mucosa
457:
453:
449:
446:
445:
433:
432:
424:
413:
407:
406:
403:RNA expression
395:
394:
391:
390:
382:
378:
377:
369:
366:
361:
355:
354:
345:
338:
332:
328:
327:
322:
316:
315:
307:
306:
294:
293:
290:
289:
281:
277:
276:
268:
265:
260:
254:
253:
244:
237:
231:
227:
226:
219:
213:
212:
204:
203:
191:
190:
147:
143:
142:
134:
126:
125:
121:
120:
117:
116:
113:
112:
82:
81:
73:
72:
61:
55:
54:
46:
45:
37:
36:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
4938:
4927:
4924:
4922:
4919:
4918:
4916:
4901:
4898:
4896:
4893:
4891:
4888:
4886:
4883:
4881:
4878:
4876:
4873:
4871:
4868:
4866:
4863:
4861:
4858:
4856:
4853:
4851:
4848:
4846:
4843:
4841:
4838:
4836:
4833:
4831:
4828:
4826:
4823:
4821:
4818:
4816:
4813:
4811:
4808:
4806:
4803:
4801:
4798:
4796:
4793:
4791:
4788:
4786:
4783:
4781:
4778:
4776:
4773:
4771:
4768:
4766:
4763:
4761:
4758:
4756:
4753:
4751:
4748:
4746:
4743:
4741:
4738:
4736:
4733:
4731:
4728:
4726:
4723:
4721:
4718:
4717:
4715:
4711:
4705:
4702:
4700:
4697:
4695:
4692:
4690:
4687:
4685:
4682:
4680:
4677:
4675:
4672:
4670:
4667:
4665:
4662:
4660:
4657:
4655:
4652:
4650:
4647:
4645:
4642:
4640:
4637:
4635:
4632:
4630:
4627:
4625:
4622:
4620:
4617:
4615:
4612:
4610:
4607:
4605:
4602:
4600:
4597:
4595:
4592:
4590:
4587:
4585:
4582:
4580:
4577:
4575:
4572:
4570:
4567:
4565:
4562:
4560:
4557:
4555:
4552:
4550:
4547:
4545:
4542:
4540:
4537:
4535:
4532:
4530:
4527:
4525:
4522:
4520:
4517:
4515:
4512:
4511:
4509:
4505:
4499:
4496:
4494:
4490:
4487:
4485:
4482:
4480:
4477:
4475:
4472:
4470:
4467:
4465:
4462:
4460:
4457:
4455:
4452:
4450:
4447:
4445:
4442:
4438:
4435:
4433:
4430:
4429:
4428:
4425:
4423:
4420:
4418:
4415:
4413:
4410:
4408:
4405:
4403:
4400:
4398:
4395:
4393:
4390:
4388:
4385:
4383:
4380:
4378:
4375:
4373:
4370:
4368:
4365:
4363:
4360:
4357:
4354:
4352:
4348:
4345:
4343:
4340:
4336:
4333:
4331:
4328:
4327:
4326:
4323:
4321:
4318:
4314:
4311:
4309:
4306:
4305:
4304:
4301:
4299:
4296:
4294:
4291:
4289:
4286:
4284:
4281:
4279:
4276:
4274:
4271:
4269:
4266:
4264:
4261:
4260:
4258:
4254:
4248:
4245:
4243:
4240:
4238:
4235:
4233:
4230:
4228:
4225:
4223:
4220:
4218:
4215:
4213:
4210:
4208:
4205:
4203:
4200:
4198:
4195:
4193:
4190:
4188:
4185:
4183:
4180:
4178:
4175:
4173:
4170:
4168:
4165:
4161:
4158:
4156:
4153:
4152:
4151:
4148:
4146:
4143:
4141:
4138:
4136:
4133:
4129:
4126:
4124:
4121:
4119:
4116:
4115:
4114:
4111:
4109:
4106:
4104:
4101:
4099:
4096:
4094:
4091:
4087:
4084:
4082:
4079:
4078:
4077:
4074:
4072:
4069:
4067:
4064:
4062:
4059:
4057:
4054:
4052:
4049:
4047:
4044:
4040:
4037:
4035:
4032:
4031:
4030:
4027:
4024:
4021:
4019:
4016:
4014:
4011:
4009:
4006:
4004:
4000:
3997:
3995:
3992:
3988:
3985:
3983:
3980:
3978:
3975:
3974:
3973:
3970:
3968:
3965:
3963:
3960:
3958:
3955:
3953:
3950:
3948:
3945:
3944:
3942:
3938:
3932:
3929:
3927:
3924:
3922:
3919:
3917:
3914:
3912:
3909:
3907:
3904:
3902:
3899:
3897:
3894:
3892:
3889:
3887:
3884:
3882:
3879:
3877:
3874:
3872:
3869:
3867:
3864:
3862:
3859:
3857:
3854:
3852:
3849:
3847:
3844:
3842:
3839:
3837:
3834:
3832:
3829:
3827:
3824:
3822:
3819:
3817:
3814:
3812:
3809:
3805:
3802:
3800:
3797:
3796:
3795:
3792:
3788:
3785:
3783:
3780:
3779:
3778:
3775:
3773:
3770:
3768:
3765:
3763:
3760:
3758:
3755:
3753:
3750:
3748:
3745:
3743:
3740:
3738:
3735:
3733:
3730:
3728:
3725:
3723:
3720:
3718:
3715:
3711:
3708:
3706:
3703:
3702:
3701:
3698:
3696:
3693:
3691:
3688:
3686:
3683:
3681:
3678:
3676:
3673:
3671:
3668:
3667:
3665:
3661:
3655:
3652:
3650:
3647:
3645:
3642:
3640:
3637:
3635:
3632:
3630:
3627:
3625:
3622:
3620:
3617:
3615:
3611:
3608:
3606:
3603:
3601:
3598:
3596:
3593:
3591:
3588:
3586:
3583:
3579:
3576:
3574:
3571:
3569:
3566:
3564:
3561:
3559:
3556:
3554:
3551:
3550:
3549:
3546:
3544:
3541:
3539:
3536:
3534:
3531:
3529:
3526:
3524:
3521:
3517:
3514:
3512:
3509:
3508:
3507:
3504:
3502:
3499:
3497:
3494:
3492:
3489:
3487:
3484:
3482:
3479:
3477:
3474:
3472:
3469:
3467:
3464:
3460:
3457:
3455:
3452:
3450:
3447:
3445:
3442:
3440:
3437:
3435:
3432:
3431:
3430:
3427:
3423:
3420:
3418:
3415:
3413:
3410:
3409:
3408:
3405:
3403:
3400:
3396:
3393:
3391:
3388:
3386:
3383:
3382:
3381:
3378:
3376:
3373:
3371:
3368:
3366:
3363:
3361:
3358:
3356:
3353:
3351:
3348:
3346:
3343:
3341:
3338:
3336:
3333:
3331:
3328:
3327:
3325:
3321:
3315:
3312:
3308:
3305:
3303:
3300:
3298:
3295:
3293:
3290:
3288:
3285:
3283:
3280:
3279:
3278:
3275:
3273:
3270:
3268:
3265:
3263:
3260:
3258:
3255:
3253:
3250:
3248:
3245:
3241:
3238:
3236:
3233:
3231:
3228:
3226:
3223:
3222:
3221:
3218:
3216:
3213:
3211:
3208:
3206:
3203:
3201:
3198:
3196:
3193:
3191:
3188:
3186:
3183:
3181:
3178:
3176:
3173:
3169:
3166:
3164:
3161:
3160:
3159:
3156:
3154:
3151:
3149:
3146:
3144:
3141:
3139:
3136:
3134:
3131:
3129:
3126:
3124:
3121:
3119:
3116:
3114:
3111:
3109:
3106:
3104:
3101:
3099:
3096:
3094:
3091:
3089:
3086:
3082:
3079:
3077:
3074:
3073:
3072:
3069:
3067:
3064:
3062:
3059:
3057:
3054:
3050:
3047:
3045:
3042:
3040:
3037:
3035:
3032:
3031:
3030:
3027:
3025:
3022:
3020:
3017:
3013:
3010:
3009:
3008:
3005:
3003:
3000:
2998:
2995:
2993:
2990:
2988:
2985:
2981:
2978:
2976:
2973:
2971:
2968:
2967:
2966:
2963:
2961:
2958:
2954:
2951:
2949:
2946:
2944:
2941:
2939:
2936:
2934:
2931:
2930:
2929:
2926:
2925:
2923:
2919:
2914:
2910:
2906:
2899:
2894:
2892:
2887:
2885:
2880:
2879:
2876:
2872:
2871:
2869:
2868:public domain
2865:
2856:
2852:
2851:
2846:
2842:
2838:
2835:
2831:
2828:
2827:
2823:
2816:
2812:
2808:
2804:
2800:
2796:
2795:Life Sciences
2791:
2787:
2783:
2779:
2773:
2769:
2765:
2761:
2756:
2752:
2748:
2743:
2738:
2734:
2730:
2726:
2722:
2718:
2713:
2709:
2705:
2700:
2695:
2691:
2687:
2684:(2): 421–31.
2683:
2679:
2675:
2670:
2666:
2662:
2657:
2652:
2648:
2644:
2640:
2635:
2631:
2627:
2623:
2619:
2615:
2611:
2606:
2602:
2598:
2594:
2590:
2586:
2582:
2577:
2573:
2569:
2565:
2561:
2557:
2553:
2549:
2545:
2540:
2536:
2532:
2528:
2524:
2521:(3): 1371–7.
2520:
2516:
2511:
2507:
2503:
2499:
2495:
2491:
2487:
2481:
2477:
2473:
2468:
2463:
2459:
2455:
2451:
2446:
2442:
2438:
2434:
2430:
2426:
2422:
2418:
2414:
2409:
2405:
2401:
2397:
2393:
2389:
2385:
2380:
2376:
2372:
2368:
2364:
2360:
2356:
2352:
2348:
2343:
2339:
2335:
2330:
2325:
2322:(3): 177–84.
2321:
2317:
2313:
2308:
2304:
2300:
2296:
2292:
2288:
2284:
2279:
2278:
2273:
2265:
2261:
2257:
2253:
2250:(2): 203–13.
2249:
2245:
2238:
2235:
2230:
2226:
2221:
2216:
2211:
2206:
2202:
2198:
2194:
2187:
2184:
2179:
2175:
2171:
2167:
2163:
2159:
2155:
2151:
2144:
2141:
2136:
2132:
2127:
2122:
2118:
2114:
2110:
2106:
2102:
2095:
2092:
2087:
2083:
2078:
2073:
2068:
2063:
2059:
2055:
2051:
2044:
2042:
2040:
2036:
2031:
2027:
2022:
2017:
2012:
2007:
2003:
1999:
1995:
1988:
1985:
1982:
1981:
1975:
1972:
1967:
1963:
1959:
1955:
1951:
1947:
1943:
1939:
1932:
1929:
1926:
1924:
1918:
1915:
1912:
1910:
1904:
1901:
1896:
1892:
1887:
1882:
1877:
1872:
1868:
1864:
1860:
1853:
1851:
1849:
1847:
1843:
1838:
1834:
1829:
1824:
1820:
1816:
1812:
1808:
1804:
1797:
1794:
1791:
1787:
1782:
1779:
1774:
1770:
1765:
1760:
1756:
1752:
1748:
1744:
1740:
1733:
1730:
1725:
1721:
1716:
1711:
1707:
1703:
1700:(5): 432–42.
1699:
1695:
1691:
1684:
1681:
1676:
1670:
1667:
1662:
1658:
1653:
1648:
1643:
1638:
1634:
1630:
1626:
1619:
1616:
1606:
1602:
1598:
1594:
1590:
1584:
1580:
1576:
1572:
1571:
1562:
1559:
1554:
1550:
1546:
1542:
1538:
1534:
1527:
1524:
1519:
1515:
1509:
1506:
1501:
1497:
1491:
1488:
1484:
1480:
1475:
1473:
1471:
1467:
1463:
1459:
1454:
1452:
1450:
1446:
1440:
1436:
1433:
1431:
1428:
1427:
1423:
1421:
1419:
1415:
1411:
1407:
1403:
1399:
1392:
1390:
1388:
1384:
1380:
1376:
1372:
1368:
1364:
1360:
1356:
1352:
1348:
1344:
1340:
1336:
1332:
1328:
1324:
1320:
1316:
1312:
1308:
1307:breast cancer
1304:
1300:
1296:
1292:
1288:
1284:
1275:
1273:
1270:
1262:
1260:
1258:
1253:
1247:
1245:
1243:
1239:
1234:
1233:proliferation
1230:
1226:
1222:
1218:
1214:
1206:
1204:
1202:
1198:
1194:
1190:
1186:
1181:
1177:
1169:
1167:
1165:
1161:
1157:
1154:
1151:
1143:
1141:
1139:
1135:
1131:
1128:
1124:
1120:
1116:
1112:
1108:
1096:
1091:
1087:
1083:
1080:
1076:
1069:
1067:
1064:
1060:
1056:
1052:
1049:
1045:
1041:
1034:
1032:
1026:
1022:
1019:
1013:
1011:
1007:
1001:
997:
994:
990:
983:
981:
975:
971:
968:
962:
960:
956:
950:
946:
943:
941:RefSeq (mRNA)
939:
932:
931:
926:
922:
919:
913:
912:
907:
903:
900:
898:
894:
887:
886:
881:
877:
874:
868:
867:
862:
858:
855:
853:
849:
842:
841:
836:
832:
829:
823:
822:
817:
813:
810:
808:
804:
801:
798:
796:
793:
789:
786:
782:
778:
771:
767:
762:
756:
753:
751:
748:
746:
743:
741:
738:
736:
733:
731:
728:
726:
723:
721:
718:
716:
713:
711:
708:
707:
705:
702:
701:
695:
692:
690:
687:
685:
682:
680:
677:
675:
672:
670:
667:
665:
662:
661:
659:
656:
655:
649:
646:
644:
641:
639:
636:
634:
631:
629:
626:
625:
623:
620:
619:
616:
615:Gene ontology
612:
608:
596:
591:
587:
582:
579:
577:
573:
565:
560:
549:
545:
541:
537:
533:
529:
525:
521:
517:
513:
512:
509:
505:
500:
497:
487:
483:
479:
475:
471:
467:
463:
459:
455:
451:
450:
447:
443:
438:
435:
434:
431:
429:
425:
423:
422:
418:
417:
414:
412:
408:
404:
400:
396:
388:
383:
379:
375:
370:
364:9|9 E3.1
360:
356:
349:
342:
336:
329:
321:
317:
313:
308:
304:
299:
295:
287:
282:
278:
274:
269:
259:
255:
248:
241:
235:
228:
224:
218:
214:
210:
205:
201:
196:
192:
188:
184:
180:
176:
172:
168:
164:
160:
156:
152:
144:
139:
132:
127:
122:
111:
109:
105:
101:
97:
93:
89:
83:
78:
75:
74:
70:
67:
60:
56:
51:
47:
43:
38:
33:
30:
19:
4426:
4346:
4324:
4302:
4149:
4112:
4075:
4028:
3998:
3971:
3793:
3699:
3547:
3490:
3276:
3028:
2861:
2860:
2848:
2798:
2794:
2759:
2724:
2720:
2681:
2677:
2646:
2642:
2613:
2609:
2587:(3): 171–3.
2584:
2580:
2550:(1): 88–92.
2547:
2543:
2518:
2514:
2489:
2485:
2457:
2453:
2416:
2412:
2390:(2): 100–4.
2387:
2383:
2350:
2346:
2319:
2315:
2289:(2): 131–9.
2286:
2282:
2247:
2243:
2237:
2200:
2196:
2186:
2153:
2149:
2143:
2108:
2104:
2094:
2057:
2053:
2001:
1997:
1987:
1979:
1974:
1941:
1937:
1931:
1922:
1917:
1908:
1903:
1866:
1862:
1810:
1806:
1796:
1781:
1749:(1): 15–27.
1746:
1742:
1732:
1697:
1693:
1683:
1669:
1632:
1628:
1618:
1608:, retrieved
1569:
1561:
1539:(3): 563–9.
1536:
1532:
1526:
1517:
1508:
1499:
1490:
1414:miR30 family
1396:
1355:A2A receptor
1335:angiogenesis
1287:glioblastoma
1279:
1266:
1254:
1251:
1210:
1173:
1147:
1126:
1114:
1110:
1106:
1105:
1028:
1006:NP_001191742
1003:
977:
959:NM_001204813
952:
928:
909:
883:
864:
838:
819:
799:
794:
689:cell surface
526:right kidney
426:
419:
146:External IDs
85:
29:
2492:(1): 9–19.
1323:fibronectin
1295:oesophageal
1121:73), is an
694:nucleoplasm
534:granulocyte
385:88,254,145
372:88,209,250
284:85,495,791
271:85,449,584
124:Identifiers
4915:Categories
2911:(see also
2353:: 95–109.
2111:(1): 515.
1610:2020-11-28
1485:, May 2017
1464:, May 2017
1441:References
1418:miR-30a-5p
1363:macrophage
1238:neutrophil
1180:lymphocyte
1158:proteins,
522:left colon
430:(ortholog)
167:HomoloGene
2178:190909472
2170:0732-183X
2060:(1): 34.
1605:208035622
1387:inhibitor
1383:anti-CD73
1225:adenosine
1138:adenosine
1031:NP_035981
1010:NP_002517
980:NM_011851
955:NM_002526
785:Orthologs
175:GeneCards
2905:Proteins
2572:22488106
2433:16709165
2404:12000134
2375:29930691
2264:26820227
2229:30568661
2203:: 2878.
2135:31980601
2086:28158983
2030:29942314
2004:: 1322.
1966:58767911
1958:30556751
1895:29720980
1837:27665459
1788:(OMIM):
1773:13149051
1724:21288095
1661:29720980
1597:31727245
1481:–
1460:–
1424:See also
1398:MicroRNA
1311:adhesion
1299:prostate
1291:melanoma
1283:leukemia
1281:such as
1170:Function
1079:Wikidata
764:Sources:
674:membrane
4713:301–350
4507:251–300
4459:CD240CE
4256:201–250
3940:151–200
3663:101–150
2855:PDBe-KB
2845:UniProt
2815:9651114
2786:9361795
2751:9169488
2708:9015312
2699:2134816
2665:8781432
2630:8566797
2601:8000038
2564:2848759
2535:2173922
2506:2137649
2441:8728207
2367:9553767
2338:9238677
2303:9113412
2220:6290335
2126:6981126
2077:5291990
2021:6004379
1886:5915482
1869:: 813.
1828:5126201
1764:1030367
1715:3049958
1652:5915482
1635:: 813.
1553:2129526
1483:Ensembl
1462:Ensembl
1327:laminin
1303:ovarian
1197:femoral
897:UniProt
852:Ensembl
791:Species
770:QuickGO
684:cytosol
405:pattern
131:Aliases
4720:CD300A
4679:CDw293
4464:CD240D
4325:CD213a
4303:CDw210
4268:CD202b
4242:CDw199
4237:CDw198
3891:CD140b
3323:51–100
2850:P21589
2836:(MeSH)
2813:
2784:
2774:
2749:
2742:508104
2739:
2706:
2696:
2663:
2628:
2599:
2570:
2562:
2533:
2504:
2476:819433
2474:
2439:
2431:
2402:
2373:
2365:
2336:
2301:
2262:
2227:
2217:
2176:
2168:
2133:
2123:
2084:
2074:
2028:
2018:
1964:
1956:
1893:
1883:
1835:
1825:
1790:211800
1771:
1761:
1722:
1712:
1659:
1649:
1603:
1595:
1585:
1551:
1351:T cell
1276:Cancer
1213:enzyme
1199:, and
1123:enzyme
1065:search
1063:PubMed
930:Q61503
911:P21589
807:Entrez
576:BioGPS
263:6q14.3
155:129190
4900:CD350
4895:CD349
4890:CD344
4885:CD340
4880:CD339
4875:CD338
4870:CD337
4865:CD336
4860:CD335
4855:CD334
4850:CD333
4845:CD332
4840:CD331
4835:CD329
4830:CD328
4825:CD327
4820:CD326
4815:CD325
4810:CD324
4805:CD322
4800:CD321
4795:CD320
4790:CD318
4785:CD317
4780:CD316
4775:CD315
4770:CD314
4765:CD312
4760:CD309
4755:CD307
4750:CD306
4745:CD305
4740:CD304
4735:CD303
4730:CD302
4725:CD301
4704:CD299
4699:CD298
4694:CD297
4689:CD295
4684:CD294
4674:CD292
4669:CD290
4664:CD289
4659:CD288
4654:CD286
4649:CD284
4644:CD283
4639:CD282
4634:CD281
4629:CD280
4624:CD279
4619:CD278
4614:CD276
4609:CD275
4604:CD274
4599:CD273
4594:CD272
4589:CD271
4584:CD269
4579:CD268
4574:CD267
4569:CD266
4564:CD265
4559:CD264
4554:CD263
4549:CD262
4544:CD261
4539:CD258
4534:CD257
4529:CD256
4524:CD254
4519:CD253
4514:CD252
4498:CD249
4493:CD248
4489:CD247
4484:CD246
4479:CD244
4474:CD243
4469:CD241
4454:CD239
4449:CD238
4444:CD236
4427:CD235
4422:CD234
4417:CD233
4412:CD230
4407:CD229
4402:CD228
4397:CD227
4392:CD226
4387:CD225
4382:CD224
4377:CD223
4372:CD222
4367:CD221
4362:CD220
4347:CD218
4342:CD217
4320:CD212
4298:CD209
4293:CD208
4288:CD207
4283:CD206
4278:CD205
4273:CD204
4263:CD201
4247:CD200
4232:CD197
4227:CD196
4222:CD195
4217:CD194
4212:CD193
4207:CD192
4202:CD191
4197:CD186
4192:CD185
4187:CD184
4182:CD183
4177:CD182
4172:CD181
4167:CD180
4150:CD179
4145:CD178
4140:CD177
4135:CD174
4113:CD172
4108:CD171
4103:CD170
4098:CD169
4093:CD168
4076:CD167
4071:CD166
4066:CD164
4061:CD163
4056:CD162
4051:CD161
4046:CD160
4029:CD159
3999:CD158
3994:CD157
3972:CD156
3967:CD155
3962:CD154
3957:CD153
3952:CD152
3947:CD151
3931:CD150
3926:CD148
3921:CD147
3916:CD146
3911:CD144
3906:CD143
3901:CD142
3896:CD141
3886:CD138
3881:CD137
3876:CD136
3871:CD135
3866:CD134
3861:CD133
3856:CD132
3851:CD131
3846:CD130
3841:CD129
3836:CD127
3831:CD126
3826:CD125
3821:CD124
3816:CD123
3811:CD122
3794:CD121
3777:CD120
3772:CD119
3767:CD118
3762:CD117
3757:CD116
3752:CD115
3747:CD114
3742:CD113
3737:CD112
3732:CD111
3727:CD110
3722:CD109
3717:CD108
3700:CD107
3695:CD106
3690:CD105
3685:CD104
3680:CD103
3675:CD102
3670:CD101
3654:CD100
2643:Blood
2568:S2CID
2437:S2CID
2371:S2CID
2174:S2CID
1962:S2CID
1601:S2CID
1393:miRNA
1193:iliac
1164:c-AMP
1153:AP-2,
840:23959
800:Mouse
795:Human
766:Amigo
488:tibia
428:Mouse
421:Human
368:Start
303:Mouse
267:Start
200:Human
163:99782
3649:CD99
3644:CD98
3639:CD97
3634:CD96
3629:CD95
3624:CD94
3619:CD93
3614:CD92
3610:CD91
3605:CD90
3600:CD89
3595:CD88
3590:CD87
3585:CD86
3548:CD85
3543:CD84
3538:CD83
3533:CD82
3528:CD81
3523:CD80
3506:CD79
3501:CD78
3496:CD74
3491:CD73
3486:CD72
3481:CD71
3476:CD70
3471:CD69
3466:CD68
3429:CD66
3407:CD64
3402:CD63
3380:CD62
3375:CD61
3370:CD59
3365:CD58
3360:CD57
3355:CD56
3350:CD55
3345:CD54
3340:CD53
3335:CD52
3330:CD51
3314:CD50
3277:CD49
3272:CD48
3267:CD47
3262:CD46
3257:CD45
3252:CD44
3247:CD43
3220:CD42
3215:CD41
3210:CD40
3205:CD39
3200:CD38
3195:CD37
3190:CD36
3185:CD35
3180:CD34
3175:CD33
3158:CD32
3153:CD31
3148:CD30
3143:CD29
3138:CD28
3133:CD27
3128:CD26
3123:CD25
3118:CD24
3113:CD23
3108:CD22
3103:CD21
3098:CD20
3093:CD19
3088:CD18
3071:CD16
3066:CD15
3061:CD14
3056:CD13
3029:CD11
3024:CD10
2921:1–50
2843:for
2811:PMID
2782:PMID
2772:ISBN
2747:PMID
2704:PMID
2661:PMID
2626:PMID
2610:Gene
2597:PMID
2560:PMID
2531:PMID
2502:PMID
2472:PMID
2429:PMID
2400:PMID
2363:PMID
2334:PMID
2299:PMID
2260:PMID
2225:PMID
2166:ISSN
2131:PMID
2082:PMID
2026:PMID
1954:PMID
1925:2016
1911:2018
1891:PMID
1833:PMID
1769:PMID
1720:PMID
1657:PMID
1593:PMID
1583:ISBN
1549:PMID
1373:and
1347:cAMP
1325:and
1313:and
1305:and
1219:and
1160:SP-1
1156:SMAD
1130:gene
1127:NT5E
1115:CD73
821:4907
411:Bgee
359:Band
320:Chr.
258:Band
217:Chr.
179:NT5E
171:1895
151:OMIM
138:NT5E
108:4H2G
104:4H1S
100:4H2I
96:4H2F
92:4H1Y
88:4H2B
69:RCSB
66:PDBe
35:NT5E
18:CD73
3019:CD9
3007:CD8
3002:CD7
2997:CD6
2992:CD5
2987:CD4
2965:CD3
2960:CD2
2933:a-c
2928:CD1
2841:PDB
2803:doi
2764:doi
2737:PMC
2729:doi
2694:PMC
2686:doi
2682:136
2651:doi
2618:doi
2614:167
2589:doi
2585:102
2552:doi
2523:doi
2519:172
2494:doi
2462:doi
2458:251
2421:doi
2392:doi
2355:doi
2351:161
2324:doi
2291:doi
2252:doi
2248:373
2215:PMC
2205:doi
2158:doi
2121:PMC
2113:doi
2072:PMC
2062:doi
2016:PMC
2006:doi
1946:doi
1881:PMC
1871:doi
1823:PMC
1815:doi
1759:PMC
1751:doi
1710:PMC
1702:doi
1698:364
1647:PMC
1637:doi
1575:doi
1541:doi
1537:191
1402:RNA
1221:ADP
1217:ATP
1176:AMP
1136:to
1134:AMP
1113:or
381:End
280:End
183:OMA
159:MGI
59:PDB
4917::
4491:-
3612:-
2953:1E
2948:1D
2943:1B
2938:1A
2907::
2847::
2809:.
2799:62
2797:.
2780:.
2770:.
2745:.
2735:.
2725:99
2723:.
2719:.
2702:.
2692:.
2680:.
2676:.
2659:.
2647:88
2645:.
2641:.
2624:.
2612:.
2595:.
2583:.
2566:.
2558:.
2548:81
2546:.
2529:.
2517:.
2500:.
2490:35
2488:.
2470:.
2456:.
2452:.
2435:.
2427:.
2417:34
2415:.
2398:.
2388:56
2386:.
2369:.
2361:.
2349:.
2332:.
2318:.
2314:.
2297:.
2285:.
2258:.
2246:.
2223:.
2213:.
2199:.
2195:.
2172:.
2164:.
2154:37
2152:.
2129:.
2119:.
2109:11
2107:.
2103:.
2080:.
2070:.
2058:16
2056:.
2052:.
2038:^
2024:.
2014:.
2000:.
1996:.
1960:.
1952:.
1942:23
1940:.
1889:.
1879:.
1865:.
1861:.
1845:^
1831:.
1821:.
1811:64
1809:.
1805:.
1767:.
1757:.
1747:13
1745:.
1741:.
1718:.
1708:.
1696:.
1692:.
1655:.
1645:.
1631:.
1627:.
1599:,
1591:,
1581:,
1547:.
1535:.
1516:.
1498:.
1469:^
1448:^
1381:,
1375:A3
1371:A1
1357:.
1301:,
1297:,
1293:,
1289:,
1285:,
1244:.
1195:,
1140:.
768:/
387:bp
374:bp
286:bp
273:bp
181:;
177::
173:;
169::
165:;
161::
157:;
153::
106:,
102:,
98:,
94:,
90:,
4437:b
4432:a
4358:)
4356:b
4351:a
4349:(
4335:2
4330:1
4313:b
4308:a
4160:b
4155:a
4128:g
4123:b
4118:a
4086:b
4081:a
4039:c
4034:a
4025:)
4023:k
4018:i
4013:e
4008:d
4003:a
4001:(
3987:c
3982:b
3977:a
3804:b
3799:a
3787:b
3782:a
3710:b
3705:a
3578:k
3573:j
3568:h
3563:e
3558:d
3553:a
3516:b
3511:a
3459:f
3454:e
3449:d
3444:c
3439:b
3434:a
3422:C
3417:B
3412:A
3395:P
3390:L
3385:E
3307:f
3302:e
3297:d
3292:c
3287:b
3282:a
3240:d
3235:c
3230:b
3225:a
3168:B
3163:A
3081:B
3076:A
3049:d
3044:c
3039:b
3034:a
3012:a
2980:ε
2975:δ
2970:γ
2915:)
2897:e
2890:t
2883:v
2870:.
2857:.
2817:.
2805::
2788:.
2766::
2753:.
2731::
2710:.
2688::
2667:.
2653::
2632:.
2620::
2603:.
2591::
2574:.
2554::
2537:.
2525::
2508:.
2496::
2478:.
2464::
2443:.
2423::
2406:.
2394::
2377:.
2357::
2340:.
2326::
2320:2
2305:.
2293::
2287:9
2266:.
2254::
2231:.
2207::
2201:9
2180:.
2160::
2137:.
2115::
2088:.
2064::
2032:.
2008::
2002:9
1968:.
1948::
1897:.
1873::
1867:9
1839:.
1817::
1775:.
1753::
1726:.
1704::
1677:.
1663:.
1639::
1633:9
1577::
1555:.
1543::
1520:.
1502:.
1117:(
305:)
202:)
185::
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
