472:
signaling events. Hardy et al. further characterized an alternate mode of BCR signaling that is induced by chronic AgR stimulation and maintains a state of B cell unresponsiveness termed "anergy". Other studies that focused on the deficiencies observed in neonatal antibody production can be due to various intrinsic features such as B-cell immaturity, poor B-cell repertoire or reduced strength of BCR signaling. Activation of the BCR with T-cell-dependent (TD) or TI antigens induces cross-linking of surface Ig molecules and binding to the transmembrane protein CD79.
681:
Davis RE, Ngo VN, Lenz G, Tolar P, Young RM, Romesser PB, Kohlhammer H, Lamy L, Zhao H, Yang Y, Xu W, Shaffer AL, Wright G, Xiao W, Powell J, Jiang JK, Thomas CJ, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Johnson NA, Rimsza LM, Campo E, Jaffe ES, Wilson WH, Delabie J, Smeland
471:
were detected frequently in biopsy samples. Moreover, some researchers believe that CD79 may emerge as an alternative target for the treatment of B-cell-dependent autoimmunity. Hardy et al. found that upon an Ag-induced BCR aggregation, CD79 is phosphorylated and initiates a cascade of downstream
788:
Hardy IR, Anceriz N, Rousseau F, Seefeldt MB, Hatterer E, Irla M, Buatois V, Chatel LE, Getahun A, Fletcher A, Cons L, Pontini G, Hertzberg NA, Magistrelli G, Malinge P, Smith MJ, Reith W, Kosco-Vilbois MH, Ferlin WG, Cambier JC (February 2014).
2909:
646:
Nakken B, Munthe LA, Konttinen YT, Sandberg AK, Szekanecz Z, Alex P, Szodoray P (November 2011). "B-cells and their targeting in rheumatoid arthritis--current concepts and future perspectives".
443:
tyrosine-based activation motif (ITAM), which some scientists have found to propagate downstream signaling in B-cells. CD79 has been tested as a B-cell target in MRL/lpr mice, a mouse model for
2902:
1733:
872:
2895:
528:"Comparison of human B cell antigen receptor complexes: membrane-expressed forms of immunoglobulin (Ig)M, IgD, and IgG are associated with structurally related heterodimers"
463:
Scientists identified mutations in the BCR coreceptor CD79A/B that lead to chronic activation of BCR signaling. Somatic mutations affecting the ITAM signaling modules of
1723:
396:
3290:
206:
52:
1703:
575:
Müller B, Cooper L, Terhorst C (January 1995). "Interplay between the human TCR/CD3 epsilon and the B-cell antigen receptor associated Ig-beta (B29)".
2565:
889:
865:
3343:
3431:
2296:
2284:
2062:
3515:
3510:
2348:
2343:
2289:
2069:
850:
3520:
1802:
1728:
858:
2831:
2826:
2821:
2816:
1743:
230:
76:
3035:
2796:
627:
3180:
2032:
218:
64:
2600:
2094:
1780:
2239:
1775:
455:(BCR) activation and possibly depletion of ectopic germinal centers (GC). However, research on CD79 still remains very open.
211:
57:
439:
and AML has shown to potentially react positively with CD79 monoclonal antibodies. In addition, both CD79 chains contain an
2736:
2208:
2203:
2148:
1882:
1331:
2430:
2153:
444:
2887:
3332:
1748:
2922:
2460:
885:
376:
326:
1326:
2510:
1405:
844:
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EB, Fisher RI, Braziel RM, Tubbs RR, Cook JR, Weisenburger DD, Chan WC, Pierce SK, Staudt LM (January 2010).
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1817:
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1807:
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1104:
1032:
223:
69:
3096:
2918:
1161:
1079:
340:
276:
122:
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2398:
2111:
695:
2425:
2244:
348:
526:
Van Noesel CJ, Brouns GS, van
Schijndel GM, Bende RJ, Mason DY, Borst J, van Lier RA (June 1992).
1832:
1566:
3295:
3376:
3371:
3322:
3303:
820:
770:
721:
663:
623:
592:
557:
508:
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3401:
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739:
Li Y, Chen F, Putt M, Koo YK, Madaio M, Cambier JC, Cohen PL, Eisenberg RA (September 2008).
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802:
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500:
271:
126:
117:
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3208:
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452:
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146:
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740:
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683:
619:
552:
527:
372:
3504:
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2420:
1877:
968:
741:"B cell depletion with anti-CD79 mAbs ameliorates autoimmune disease in MRL/lpr mice"
588:
504:
400:
392:
384:
3190:
2776:
2084:
2074:
1605:
1571:
447:. CD79, expressed by B-cell and plasma cell precursors is a candidate that induces
404:
3019:
659:
247:
93:
3237:
3185:
3081:
3006:
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2944:
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1435:
909:
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428:
364:
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156:
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1862:
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1371:
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1361:
1216:
1000:
610:
403:
tails that they use to propagate a signal in a B cell, in a similar manner to
254:
100:
806:
791:"Anti-CD79 antibody induces B cell anergy that protects against autoimmunity"
3249:
2555:
2550:
2545:
2535:
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2520:
684:"Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma"
448:
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667:
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105:
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2801:
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2079:
1999:
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1979:
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1410:
881:
352:
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3172:
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1052:
412:
368:
242:
88:
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2015:
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1258:
1233:
1211:
1206:
1099:
1025:
1020:
1010:
468:
464:
423:
CD79 serves to be a pan-B cell marker for the detection of B-cell
360:
356:
191:
176:
37:
22:
3285:
3280:
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3222:
3212:
3120:
3104:
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3014:
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2986:
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2408:
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2218:
2198:
2193:
2183:
2178:
2057:
2010:
1970:
1625:
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1610:
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1586:
1581:
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1561:
1519:
1514:
1504:
1499:
1477:
1472:
1467:
1462:
1457:
1452:
1447:
1442:
1378:
1351:
1346:
1341:
1316:
1311:
1248:
1243:
1238:
1228:
1223:
1176:
1171:
1166:
1156:
1151:
1134:
1129:
1124:
1114:
1109:
1094:
1089:
1084:
1074:
1069:
1064:
1047:
1042:
1037:
988:
956:
951:
946:
929:
924:
919:
914:
235:
81:
2891:
854:
3259:
3245:
2383:
995:
983:
978:
973:
963:
936:
904:
355:
by the BCR. CD79 is composed of two distinct chains called
493:
3430:
3342:
3321:
3268:
3236:
3201:
3171:
3162:
3133:
3113:
3089:
3080:
3064:
3055:
3048:
3028:
3005:
2972:
2943:
2932:
2689:
2483:
2232:
1916:
1639:
1299:
897:
306:
296:
291:
270:
265:
253:
241:
229:
217:
205:
197:
187:
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175:
152:
142:
137:
116:
111:
99:
87:
75:
63:
51:
43:
33:
28:
21:
491:Chu PG, Arber DA (June 2001). "CD79: a review".
407:-generated signal transduction observed during
23:CD79a molecule, immunoglobulin-associated alpha
397:immunoreceptor tyrosine-based activation motif
177:CD79b molecule, immunoglobulin-associated beta
2903:
866:
8:
3168:
3086:
3061:
3052:
2940:
2910:
2896:
2888:
873:
859:
851:
375:. CD79a and CD79b are both members of the
363:(also known as Igα and Igβ); these form a
288:
134:
890:list of human clusters of differentiation
843:at the U.S. National Library of Medicine
814:
764:
715:
551:
480:
172:
18:
486:
484:
7:
641:
639:
532:The Journal of Experimental Medicine
620:10.1016/b978-0-12-385183-3.00002-4
445:systemic lupus erythematosus (SLE)
14:
3036:Polymeric immunoglobulin receptor
431:in some cases of T-lymphoblastic
505:10.1097/00022744-200106000-00001
379:. Human CD79a is encoded by the
3248:(with two glycoprotein chains
395:. Both CD79 chains contain an
387:, and CD79b is encoded by the
343:that forms a complex with the
1:
3344:Killer-cell IG-like receptors
3516:Genes on human chromosome 17
3511:Genes on human chromosome 19
660:10.1016/j.autrev.2011.06.010
589:10.1016/0165-2478(94)00199-2
3521:Clusters of differentiation
3432:Leukocyte IG-like receptors
886:clusters of differentiation
757:10.4049/jimmunol.181.5.2961
3537:
2923:immunoglobulin superfamily
377:immunoglobulin superfamily
451:as well as inhibition of
351:following recognition of
287:
133:
845:Medical Subject Headings
807:10.4049/jimmunol.1302672
612:Atlas of Hematopathology
383:gene that is located on
2919:Transmembrane receptors
544:10.1084/jem.175.6.1511
459:CD79 and BCR Signaling
347:(BCR) and generates a
795:Journal of Immunology
745:Journal of Immunology
391:gene that located on
341:transmembrane protein
648:Autoimmunity Reviews
367:on the surface of a
3269:Accessory molecules
3134:Accessory molecules
708:10.1038/nature08638
700:2010Natur.463...88D
3333:cytokine receptors
2933:Antibody receptor:
614:. pp. 25–46.
577:Immunology Letters
3498:
3497:
3323:Cytokine receptor
3317:
3316:
3313:
3312:
3158:
3157:
3129:
3128:
3044:
3043:
2885:
2884:
373:disulfide bonding
320:
319:
316:
315:
166:
165:
162:
161:
3528:
3202:Antigen receptor
3169:
3087:
3065:Antigen receptor
3062:
3053:
3049:Antigen receptor
3007:Alpha (α)/mu (μ)
2941:
2926:immune receptors
2912:
2905:
2898:
2889:
875:
868:
861:
852:
829:
828:
818:
785:
779:
778:
768:
736:
730:
729:
719:
678:
672:
671:
643:
634:
633:
607:
601:
600:
572:
566:
565:
555:
523:
517:
516:
488:
399:(ITAM) in their
289:
173:
135:
19:
3536:
3535:
3531:
3530:
3529:
3527:
3526:
3525:
3501:
3500:
3499:
3494:
3426:
3338:
3309:
3264:
3232:
3197:
3154:
3125:
3109:
3076:
3040:
3024:
3001:
2968:
2934:
2928:
2916:
2886:
2881:
2685:
2479:
2228:
1912:
1635:
1295:
893:
879:
837:
832:
787:
786:
782:
738:
737:
733:
694:(7277): 88–92.
680:
679:
675:
645:
644:
637:
630:
609:
608:
604:
583:(2–3): 97–103.
574:
573:
569:
525:
524:
520:
490:
489:
482:
478:
461:
453:B-cell receptor
421:
409:T cell receptor
345:B-cell receptor
171:
17:
12:
11:
5:
3534:
3532:
3524:
3523:
3518:
3513:
3503:
3502:
3496:
3495:
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3487:
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3472:
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3452:
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3434:
3428:
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3425:
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3419:
3414:
3409:
3404:
3399:
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3389:
3384:
3379:
3374:
3369:
3364:
3359:
3354:
3348:
3346:
3340:
3339:
3337:
3336:
3327:
3325:
3319:
3318:
3315:
3314:
3311:
3310:
3308:
3307:
3293:
3288:
3283:
3278:
3272:
3270:
3266:
3265:
3263:
3262:
3257:
3242:
3240:
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3233:
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3230:
3225:
3220:
3215:
3205:
3203:
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3131:
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3127:
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3117:
3115:
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3110:
3108:
3107:
3093:
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3084:
3078:
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3066:
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3050:
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3041:
3039:
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3032:
3030:
3026:
3025:
3023:
3022:
3017:
3011:
3009:
3003:
3002:
3000:
2999:
2994:
2989:
2984:
2978:
2976:
2970:
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2967:
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2955:
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2938:
2930:
2929:
2917:
2915:
2914:
2907:
2900:
2892:
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2879:
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2829:
2824:
2819:
2814:
2809:
2804:
2799:
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2789:
2784:
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2734:
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2709:
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2628:
2623:
2618:
2613:
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2603:
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2593:
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2573:
2568:
2563:
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2548:
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2528:
2523:
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2513:
2508:
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2411:
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1997:
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1973:
1968:
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1956:
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1931:
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1911:
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1613:
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1593:
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1569:
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1512:
1507:
1502:
1497:
1496:
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1460:
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1433:
1428:
1423:
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1413:
1403:
1402:
1401:
1396:
1391:
1381:
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1354:
1349:
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1339:
1334:
1329:
1324:
1319:
1314:
1309:
1303:
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1297:
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1276:
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1251:
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1231:
1226:
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1220:
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1214:
1209:
1204:
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1189:
1184:
1179:
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1169:
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1159:
1154:
1149:
1148:
1147:
1142:
1132:
1127:
1122:
1117:
1112:
1107:
1102:
1097:
1092:
1087:
1082:
1077:
1072:
1067:
1062:
1061:
1060:
1055:
1045:
1040:
1035:
1030:
1029:
1028:
1023:
1018:
1013:
1003:
998:
993:
992:
991:
981:
976:
971:
966:
961:
960:
959:
954:
949:
939:
934:
933:
932:
927:
922:
917:
912:
901:
899:
895:
894:
880:
878:
877:
870:
863:
855:
849:
848:
836:
835:External links
833:
831:
830:
801:(4): 1641–50.
780:
751:(5): 2961–72.
731:
673:
635:
628:
602:
567:
518:
479:
477:
474:
460:
457:
441:immunoreceptor
420:
417:
411:activation on
371:stabilized by
334:ifferentiation
318:
317:
314:
313:
308:
304:
303:
298:
294:
293:
285:
284:
274:
268:
267:
263:
262:
257:
251:
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199:
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167:
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154:
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144:
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131:
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120:
114:
113:
109:
108:
103:
97:
96:
91:
85:
84:
79:
73:
72:
67:
61:
60:
55:
49:
48:
45:
41:
40:
35:
31:
30:
26:
25:
16:Protein family
15:
13:
10:
9:
6:
4:
3:
2:
3533:
3522:
3519:
3517:
3514:
3512:
3509:
3508:
3506:
3491:
3488:
3486:
3483:
3481:
3478:
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3468:
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3446:
3443:
3441:
3438:
3437:
3435:
3433:
3429:
3423:
3420:
3418:
3415:
3413:
3410:
3408:
3405:
3403:
3400:
3398:
3395:
3393:
3390:
3388:
3385:
3383:
3380:
3378:
3375:
3373:
3370:
3368:
3365:
3363:
3360:
3358:
3355:
3353:
3350:
3349:
3347:
3345:
3341:
3335:
3334:
3329:
3328:
3326:
3324:
3320:
3305:
3301:
3298:(also called
3297:
3294:
3292:
3289:
3287:
3284:
3282:
3279:
3277:
3274:
3273:
3271:
3267:
3261:
3258:
3255:
3251:
3247:
3244:
3243:
3241:
3239:
3235:
3229:
3226:
3224:
3221:
3219:
3216:
3214:
3210:
3207:
3206:
3204:
3200:
3192:
3189:
3187:
3184:
3183:
3182:
3179:
3178:
3176:
3174:
3170:
3167:
3165:
3161:
3150:
3146:
3142:
3139:
3138:
3136:
3132:
3122:
3119:
3118:
3116:
3112:
3106:
3102:
3098:
3095:
3094:
3092:
3088:
3085:
3083:
3079:
3073:
3070:
3069:
3067:
3063:
3060:
3058:
3054:
3051:
3047:
3037:
3034:
3033:
3031:
3027:
3021:
3018:
3016:
3013:
3012:
3010:
3008:
3004:
2998:
2995:
2993:
2990:
2988:
2985:
2983:
2980:
2979:
2977:
2975:
2971:
2964:
2963:C-type lectin
2960:
2956:
2954:
2951:
2950:
2948:
2946:
2942:
2939:
2937:
2931:
2927:
2924:
2920:
2913:
2908:
2906:
2901:
2899:
2894:
2893:
2890:
2878:
2875:
2873:
2870:
2868:
2865:
2863:
2860:
2858:
2855:
2853:
2850:
2848:
2845:
2843:
2840:
2838:
2835:
2833:
2830:
2828:
2825:
2823:
2820:
2818:
2815:
2813:
2810:
2808:
2805:
2803:
2800:
2798:
2795:
2793:
2790:
2788:
2785:
2783:
2780:
2778:
2775:
2773:
2770:
2768:
2765:
2763:
2760:
2758:
2755:
2753:
2750:
2748:
2745:
2743:
2740:
2738:
2735:
2733:
2730:
2728:
2725:
2723:
2720:
2718:
2715:
2713:
2710:
2708:
2705:
2703:
2700:
2698:
2695:
2694:
2692:
2688:
2682:
2679:
2677:
2674:
2672:
2669:
2667:
2664:
2662:
2659:
2657:
2654:
2652:
2649:
2647:
2644:
2642:
2639:
2637:
2634:
2632:
2629:
2627:
2624:
2622:
2619:
2617:
2614:
2612:
2609:
2607:
2604:
2602:
2599:
2597:
2594:
2592:
2589:
2587:
2584:
2582:
2579:
2577:
2574:
2572:
2569:
2567:
2564:
2562:
2559:
2557:
2554:
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2549:
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2534:
2532:
2529:
2527:
2524:
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2514:
2512:
2509:
2507:
2504:
2502:
2499:
2497:
2494:
2492:
2489:
2488:
2486:
2482:
2476:
2473:
2471:
2467:
2464:
2462:
2459:
2457:
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2442:
2439:
2437:
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2329:
2325:
2322:
2320:
2317:
2313:
2310:
2308:
2305:
2304:
2303:
2300:
2298:
2295:
2291:
2288:
2286:
2283:
2282:
2281:
2278:
2276:
2273:
2271:
2268:
2266:
2263:
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2258:
2256:
2253:
2251:
2248:
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2243:
2241:
2238:
2237:
2235:
2231:
2225:
2222:
2220:
2217:
2215:
2212:
2210:
2207:
2205:
2202:
2200:
2197:
2195:
2192:
2190:
2187:
2185:
2182:
2180:
2177:
2175:
2172:
2170:
2167:
2165:
2162:
2160:
2157:
2155:
2152:
2150:
2147:
2145:
2142:
2138:
2135:
2133:
2130:
2129:
2128:
2125:
2123:
2120:
2118:
2115:
2113:
2110:
2106:
2103:
2101:
2098:
2096:
2093:
2092:
2091:
2088:
2086:
2083:
2081:
2078:
2076:
2073:
2071:
2068:
2064:
2061:
2059:
2056:
2055:
2054:
2051:
2049:
2046:
2044:
2041:
2039:
2036:
2034:
2031:
2029:
2026:
2024:
2021:
2017:
2014:
2012:
2009:
2008:
2007:
2004:
2001:
1998:
1996:
1993:
1991:
1988:
1986:
1983:
1981:
1977:
1974:
1972:
1969:
1965:
1962:
1960:
1957:
1955:
1952:
1951:
1950:
1947:
1945:
1942:
1940:
1937:
1935:
1932:
1930:
1927:
1925:
1922:
1921:
1919:
1915:
1909:
1906:
1904:
1901:
1899:
1896:
1894:
1891:
1889:
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1881:
1879:
1876:
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1700:
1697:
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1523:
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1518:
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1513:
1511:
1508:
1506:
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1501:
1498:
1494:
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1489:
1486:
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1484:
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1474:
1471:
1469:
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1441:
1437:
1434:
1432:
1429:
1427:
1424:
1422:
1419:
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1414:
1412:
1409:
1408:
1407:
1404:
1400:
1397:
1395:
1392:
1390:
1387:
1386:
1385:
1382:
1380:
1377:
1373:
1370:
1368:
1365:
1363:
1360:
1359:
1358:
1355:
1353:
1350:
1348:
1345:
1343:
1340:
1338:
1335:
1333:
1330:
1328:
1325:
1323:
1320:
1318:
1315:
1313:
1310:
1308:
1305:
1304:
1302:
1298:
1292:
1289:
1285:
1282:
1280:
1277:
1275:
1272:
1270:
1267:
1265:
1262:
1260:
1257:
1256:
1255:
1252:
1250:
1247:
1245:
1242:
1240:
1237:
1235:
1232:
1230:
1227:
1225:
1222:
1218:
1215:
1213:
1210:
1208:
1205:
1203:
1200:
1199:
1198:
1195:
1193:
1190:
1188:
1185:
1183:
1180:
1178:
1175:
1173:
1170:
1168:
1165:
1163:
1160:
1158:
1155:
1153:
1150:
1146:
1143:
1141:
1138:
1137:
1136:
1133:
1131:
1128:
1126:
1123:
1121:
1118:
1116:
1113:
1111:
1108:
1106:
1103:
1101:
1098:
1096:
1093:
1091:
1088:
1086:
1083:
1081:
1078:
1076:
1073:
1071:
1068:
1066:
1063:
1059:
1056:
1054:
1051:
1050:
1049:
1046:
1044:
1041:
1039:
1036:
1034:
1031:
1027:
1024:
1022:
1019:
1017:
1014:
1012:
1009:
1008:
1007:
1004:
1002:
999:
997:
994:
990:
987:
986:
985:
982:
980:
977:
975:
972:
970:
967:
965:
962:
958:
955:
953:
950:
948:
945:
944:
943:
940:
938:
935:
931:
928:
926:
923:
921:
918:
916:
913:
911:
908:
907:
906:
903:
902:
900:
896:
891:
887:
883:
876:
871:
869:
864:
862:
857:
856:
853:
846:
842:
841:CD79+Antigens
839:
838:
834:
826:
822:
817:
812:
808:
804:
800:
796:
792:
784:
781:
776:
772:
767:
762:
758:
754:
750:
746:
742:
735:
732:
727:
723:
718:
713:
709:
705:
701:
697:
693:
689:
685:
677:
674:
669:
665:
661:
657:
653:
649:
642:
640:
636:
631:
629:9780123851833
625:
621:
617:
613:
606:
603:
598:
594:
590:
586:
582:
578:
571:
568:
563:
559:
554:
549:
545:
541:
538:(6): 1511–9.
537:
533:
529:
522:
519:
514:
510:
506:
502:
499:(2): 97–106.
498:
494:
487:
485:
481:
475:
473:
470:
466:
458:
456:
454:
450:
446:
442:
438:
434:
430:
426:
418:
416:
414:
410:
406:
402:
401:intracellular
398:
394:
393:chromosome 17
390:
386:
385:chromosome 19
382:
378:
374:
370:
366:
362:
358:
354:
350:
346:
342:
338:
335:
333:
329:
324:
312:
309:
305:
302:
299:
295:
290:
286:
283:
282:
278:
275:
273:
269:
264:
261:
258:
256:
252:
249:
246:
244:
240:
237:
234:
232:
228:
225:
222:
220:
216:
213:
210:
208:
204:
200:
196:
193:
190:
186:
181:
178:
174:
168:
158:
155:
151:
148:
145:
141:
136:
132:
129:
128:
124:
121:
119:
115:
110:
107:
104:
102:
98:
95:
92:
90:
86:
83:
80:
78:
74:
71:
68:
66:
62:
59:
56:
54:
50:
46:
42:
39:
36:
32:
27:
24:
20:
3330:
3238:Co-receptors
3191:MHC class II
3148:
2403:
2323:
2301:
2279:
2126:
2089:
2052:
2005:
1975:
1948:
1770:
1676:
1524:
1482:
1253:
1005:
798:
794:
783:
748:
744:
734:
691:
687:
676:
654:(1): 28–34.
651:
647:
611:
605:
580:
576:
570:
535:
531:
521:
496:
492:
462:
422:
388:
380:
336:
331:
327:
322:
321:
279:
198:Alt. symbols
169:Introduction
125:
44:Alt. symbols
3186:MHC class I
3082:Co-receptor
2945:Epsilon (ε)
2936:Fc receptor
429:tumor cells
427:. However,
365:heterodimer
301:Swiss-model
183:Identifiers
147:Swiss-model
29:Identifiers
3505:Categories
3090:stimulate:
888:(see also
476:References
330:luster of
297:Structures
292:Search for
266:Other data
143:Structures
138:Search for
112:Other data
3029:Secretory
2974:Gamma (γ)
449:apoptosis
425:neoplasms
248:NM_021602
207:NCBI gene
94:NM_001783
53:NCBI gene
3377:KIR2DL5B
3372:KIR2DL5A
3114:inhibit:
2997:Neonatal
882:Proteins
825:24442438
775:18713966
726:20054396
668:21777703
513:11396639
437:lymphoma
433:leukemia
419:Function
311:InterPro
157:InterPro
47:IG-alpha
3422:KIR3DS1
3417:KIR3DL3
3412:KIR3DL2
3407:KIR3DL1
3402:KIR2DS5
3397:KIR2DS4
3392:KIR2DS3
3387:KIR2DS2
3382:KIR2DS1
3367:KIR2DL4
3362:KIR2DL3
3357:KIR2DL2
3352:KIR2DL1
3296:ζ-chain
3173:Ligands
3164:T cells
3057:B cells
2992:FcγRIII
2690:301–350
2484:251–300
2436:CD240CE
2233:201–250
1917:151–200
1640:101–150
816:3941979
766:2865432
717:2845535
696:Bibcode
597:7541024
562:1375264
553:2119249
413:T cells
353:antigen
339:) is a
307:Domains
277:Chr. 17
255:UniProt
201:IG-beta
153:Domains
123:Chr. 19
101:UniProt
3490:LILRB5
3485:LILRB4
3480:LILRB3
3475:LILRB2
3470:LILRB1
3465:LILRA6
3460:LILRA5
3455:LILRA4
3450:LILRA3
3445:LILRA2
3440:LILRA1
3020:Fcα/μR
2987:FcγRII
2959:FcεRII
2697:CD300A
2656:CDw293
2441:CD240D
2302:CD213a
2280:CDw210
2245:CD202b
2219:CDw199
2214:CDw198
1868:CD140b
1300:51–100
847:(MeSH)
823:
813:
773:
763:
724:
714:
688:Nature
666:
626:
595:
560:
550:
511:
369:B cell
349:signal
260:P40259
243:RefSeq
236:147245
188:Symbol
106:P11912
89:RefSeq
82:112205
34:Symbol
3015:FcαRI
2982:FcγRI
2953:FcεRI
2877:CD350
2872:CD349
2867:CD344
2862:CD340
2857:CD339
2852:CD338
2847:CD337
2842:CD336
2837:CD335
2832:CD334
2827:CD333
2822:CD332
2817:CD331
2812:CD329
2807:CD328
2802:CD327
2797:CD326
2792:CD325
2787:CD324
2782:CD322
2777:CD321
2772:CD320
2767:CD318
2762:CD317
2757:CD316
2752:CD315
2747:CD314
2742:CD312
2737:CD309
2732:CD307
2727:CD306
2722:CD305
2717:CD304
2712:CD303
2707:CD302
2702:CD301
2681:CD299
2676:CD298
2671:CD297
2666:CD295
2661:CD294
2651:CD292
2646:CD290
2641:CD289
2636:CD288
2631:CD286
2626:CD284
2621:CD283
2616:CD282
2611:CD281
2606:CD280
2601:CD279
2596:CD278
2591:CD276
2586:CD275
2581:CD274
2576:CD273
2571:CD272
2566:CD271
2561:CD269
2556:CD268
2551:CD267
2546:CD266
2541:CD265
2536:CD264
2531:CD263
2526:CD262
2521:CD261
2516:CD258
2511:CD257
2506:CD256
2501:CD254
2496:CD253
2491:CD252
2475:CD249
2470:CD248
2466:CD247
2461:CD246
2456:CD244
2451:CD243
2446:CD241
2431:CD239
2426:CD238
2421:CD236
2404:CD235
2399:CD234
2394:CD233
2389:CD230
2384:CD229
2379:CD228
2374:CD227
2369:CD226
2364:CD225
2359:CD224
2354:CD223
2349:CD222
2344:CD221
2339:CD220
2324:CD218
2319:CD217
2297:CD212
2275:CD209
2270:CD208
2265:CD207
2260:CD206
2255:CD205
2250:CD204
2240:CD201
2224:CD200
2209:CD197
2204:CD196
2199:CD195
2194:CD194
2189:CD193
2184:CD192
2179:CD191
2174:CD186
2169:CD185
2164:CD184
2159:CD183
2154:CD182
2149:CD181
2144:CD180
2127:CD179
2122:CD178
2117:CD177
2112:CD174
2090:CD172
2085:CD171
2080:CD170
2075:CD169
2070:CD168
2053:CD167
2048:CD166
2043:CD164
2038:CD163
2033:CD162
2028:CD161
2023:CD160
2006:CD159
1976:CD158
1971:CD157
1949:CD156
1944:CD155
1939:CD154
1934:CD153
1929:CD152
1924:CD151
1908:CD150
1903:CD148
1898:CD147
1893:CD146
1888:CD144
1883:CD143
1878:CD142
1873:CD141
1863:CD138
1858:CD137
1853:CD136
1848:CD135
1843:CD134
1838:CD133
1833:CD132
1828:CD131
1823:CD130
1818:CD129
1813:CD127
1808:CD126
1803:CD125
1798:CD124
1793:CD123
1788:CD122
1771:CD121
1754:CD120
1749:CD119
1744:CD118
1739:CD117
1734:CD116
1729:CD115
1724:CD114
1719:CD113
1714:CD112
1709:CD111
1704:CD110
1699:CD109
1694:CD108
1677:CD107
1672:CD106
1667:CD105
1662:CD104
1657:CD103
1652:CD102
1647:CD101
1631:CD100
469:CD79A
465:CD79B
361:CD79B
357:CD79A
272:Locus
192:CD79B
127:q13.2
118:Locus
38:CD79A
3331:see
3304:TCRζ
3302:and
3300:CD3ζ
3291:CD3ε
3286:CD3δ
3281:CD3γ
3254:CD8β
3252:and
3250:CD8α
3228:TRG@
3223:TRD@
3218:TRB@
3213:TRA@
3149:CD79
3145:Ig-β
3141:Ig-α
3121:CD22
3105:CD81
3101:CD19
3097:CD21
1626:CD99
1621:CD98
1616:CD97
1611:CD96
1606:CD95
1601:CD94
1596:CD93
1591:CD92
1587:CD91
1582:CD90
1577:CD89
1572:CD88
1567:CD87
1562:CD86
1525:CD85
1520:CD84
1515:CD83
1510:CD82
1505:CD81
1500:CD80
1483:CD79
1478:CD78
1473:CD74
1468:CD73
1463:CD72
1458:CD71
1453:CD70
1448:CD69
1443:CD68
1406:CD66
1384:CD64
1379:CD63
1357:CD62
1352:CD61
1347:CD59
1342:CD58
1337:CD57
1332:CD56
1327:CD55
1322:CD54
1317:CD53
1312:CD52
1307:CD51
1291:CD50
1254:CD49
1249:CD48
1244:CD47
1239:CD46
1234:CD45
1229:CD44
1224:CD43
1197:CD42
1192:CD41
1187:CD40
1182:CD39
1177:CD38
1172:CD37
1167:CD36
1162:CD35
1157:CD34
1152:CD33
1135:CD32
1130:CD31
1125:CD30
1120:CD29
1115:CD28
1110:CD27
1105:CD26
1100:CD25
1095:CD24
1090:CD23
1085:CD22
1080:CD21
1075:CD20
1070:CD19
1065:CD18
1048:CD16
1043:CD15
1038:CD14
1033:CD13
1006:CD11
1001:CD10
898:1–50
821:PMID
771:PMID
722:PMID
664:PMID
624:ISBN
593:PMID
558:PMID
509:PMID
467:and
381:mb-1
359:and
323:CD79
231:OMIM
224:1699
219:HGNC
77:OMIM
70:1698
65:HGNC
3276:CD3
3260:CD4
3246:CD8
3209:TCR
3181:MHC
3072:BCR
2961:is
996:CD9
984:CD8
979:CD7
974:CD6
969:CD5
964:CD4
942:CD3
937:CD2
910:a-c
905:CD1
811:PMC
803:doi
799:192
761:PMC
753:doi
749:181
712:PMC
704:doi
692:463
656:doi
616:doi
585:doi
548:PMC
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281:q23
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2312:2
2307:1
2290:b
2285:a
2137:b
2132:a
2105:g
2100:b
2095:a
2063:b
2058:a
2016:c
2011:a
2002:)
2000:k
1995:i
1990:e
1985:d
1980:a
1978:(
1964:c
1959:b
1954:a
1781:b
1776:a
1764:b
1759:a
1687:b
1682:a
1555:k
1550:j
1545:h
1540:e
1535:d
1530:a
1493:b
1488:a
1436:f
1431:e
1426:d
1421:c
1416:b
1411:a
1399:C
1394:B
1389:A
1372:P
1367:L
1362:E
1284:f
1279:e
1274:d
1269:c
1264:b
1259:a
1217:d
1212:c
1207:b
1202:a
1145:B
1140:A
1058:B
1053:A
1026:d
1021:c
1016:b
1011:a
989:a
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