Knowledge (XXG)

CUT domain

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26: 204:"Isoforms of hepatocyte nuclear factor-6 differ in DNA-binding properties, contain a bifunctional homeodomain, and define the new ONECUT class of homeodomain proteins" 125: 73: 181:
display two modes of DNA binding, which hinge on the homeodomain and on the linker that separates it from the CUT domain, and two modes of
145: 312: 182: 133: 245:"Structural basis for recognition of the matrix attachment region of DNA by transcription factor SATB1" 129: 86: 274: 225: 170: 120: 264: 256: 215: 112: 269: 244: 306: 166: 78: 54: 108: 298: 66: 174: 220: 203: 278: 229: 82: 25: 294: 260: 61: 178: 140: 290: 102: 49: 162: 202:
Lannoy VJ, Burglin TR, Rousseau GG, Lemaigre FP (May 1998).
243:
Yamasaki, K.; Akiba, T.; Yamasaki, T.; Harata, K. (2007).
30:
solution structure of the second cut domain of human satb2
289:
This article incorporates text from the public domain
177:, which is often found downstream of the CUT domain. 139: 119: 101: 96: 72: 60: 48: 40: 35: 18: 185:stimulation, which hinge on the homeodomain. 8: 93: 24: 268: 219: 173:independently or in cooperation with the 194: 15: 7: 14: 1: 97:Available protein structures: 161:(also known as ONECUT) is a 329: 288: 157:In molecular biology, the 92: 23: 221:10.1074/jbc.273.22.13552 249:Nucleic Acids Research 261:10.1093/nar/gkm504 255:(15): 5073–5084. 155: 154: 151: 150: 146:structure summary 320: 283: 282: 272: 240: 234: 233: 223: 214:(22): 13552–62. 199: 94: 28: 16: 328: 327: 323: 322: 321: 319: 318: 317: 313:Protein domains 303: 302: 301: 287: 286: 242: 241: 237: 201: 200: 196: 191: 183:transcriptional 31: 12: 11: 5: 326: 324: 316: 315: 305: 304: 285: 284: 235: 193: 192: 190: 187: 153: 152: 149: 148: 143: 137: 136: 123: 117: 116: 106: 99: 98: 90: 89: 76: 70: 69: 64: 58: 57: 52: 46: 45: 42: 38: 37: 33: 32: 29: 21: 20: 13: 10: 9: 6: 4: 3: 2: 325: 314: 311: 310: 308: 300: 296: 292: 280: 276: 271: 266: 262: 258: 254: 250: 246: 239: 236: 231: 227: 222: 217: 213: 209: 208:J. Biol. Chem 205: 198: 195: 188: 186: 184: 180: 176: 172: 168: 164: 160: 147: 144: 142: 138: 135: 131: 127: 124: 122: 118: 114: 110: 107: 104: 100: 95: 91: 88: 84: 80: 77: 75: 71: 68: 65: 63: 59: 56: 53: 51: 47: 43: 39: 34: 27: 22: 17: 252: 248: 238: 211: 207: 197: 158: 156: 175:homeodomain 36:Identifiers 189:References 169:which can 159:CUT domain 109:structures 299:IPR003350 165:-binding 67:IPR003350 307:Category 295:InterPro 279:17652321 179:Proteins 126:RCSB PDB 62:InterPro 270:1976457 230:9593691 55:PF02376 277:  267:  228:  141:PDBsum 115:  105:  87:SUPFAM 41:Symbol 167:motif 83:SCOPe 74:SCOP2 293:and 291:Pfam 275:PMID 226:PMID 171:bind 134:PDBj 130:PDBe 113:ECOD 103:Pfam 79:1wh6 50:Pfam 265:PMC 257:doi 216:doi 212:273 163:DNA 121:PDB 44:CUT 19:CUT 309:: 297:: 273:. 263:. 253:35 251:. 247:. 224:. 210:. 206:. 132:; 128:; 111:/ 85:/ 81:/ 281:. 259:: 232:. 218::

Index


Pfam
PF02376
InterPro
IPR003350
SCOP2
1wh6
SCOPe
SUPFAM
Pfam
structures
ECOD
PDB
RCSB PDB
PDBe
PDBj
PDBsum
structure summary
DNA
motif
bind
homeodomain
Proteins
transcriptional
"Isoforms of hepatocyte nuclear factor-6 differ in DNA-binding properties, contain a bifunctional homeodomain, and define the new ONECUT class of homeodomain proteins"
doi
10.1074/jbc.273.22.13552
PMID
9593691
"Structural basis for recognition of the matrix attachment region of DNA by transcription factor SATB1"

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