271:
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24:
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D. F. MacFabe; D. P. Cain; K. Rodriguez-Capote; A. E. Franklin; J. E. Hoffman; F. Boon; A. R. Taylor; M. Kavaliers; K.-P. Ossenkopp (2007). "Neurobiological effects of intraventricular propionic acid in rats: Possible role of short-chain fatty acids on the pathogenesis and characteristics of autism
692:
In a recent well-designed translational study, human subjects fed 500 mg of calcium propionate twice daily demonstrated a modest decrease in LDL and total cholesterol, without a change in HDL. The study, only eight weeks in length, requires additional studies of both verification and longer
662:
Children were challenged with calcium propionate or placebo through daily bread in a double-blind placebo-controlled crossover trial. Although there was no significant difference by two measures, a statistically significant difference was found in the proportion of children whose behaviours
621:
Calcium propionate is used in bakery products as a mold inhibitor, typically at 0.1–0.4% (though animal feed may contain up to 1%). Mold contamination is considered a serious problem amongst bakers, and conditions commonly found in baking present near-optimal conditions for mold growth.
693:
duration to demonstrate the clinical value of this chemical. The study identified a novel regulatory circuit that links the gut microbiota metabolite propionic acid (PA), a short-chain fatty acid, with the gut immune system to control intestinal cholesterol homeostasis .
663:"worsened" with challenge (52%), compared to the proportion whose behaviour "improved" with challenge (19%). When propanoic acid was infused directly into rodents' brains, it produced reversible behavior changes (e.g. hyperactivity, dystonia, social impairment,
614:. Calcium propionate is used as a preservative in a wide variety of products, including: bread, other baked goods, processed meat, whey, and other dairy products. In agriculture, it is used, amongst other things, to prevent
631:(rope), was a serious problem, but today's improved sanitary practices in the bakery, combined with rapid turnover of the finished product, have virtually eliminated this form of spoilage. Calcium propionate and
646:
begins with its conversion to propionyl coenzyme A (propionyl-CoA), the usual first step in the metabolism of carboxylic acids. Since propanoic acid has three carbons, propionyl-CoA cannot directly enter the
618:
in cows and as a feed supplement. Propionates prevent microbes from producing the energy they need, like benzoates do. However, unlike benzoates, propionates do not require an acidic environment.
969:
Biggs, A. R.; El-Kholi, M. M.; El-Neshawy, S.; Nickerson, R. (1997). "Effects of
Calcium Salts on Growth, Polygalacturonase Activity, and Infection of Peach Fruit by Monilinia fructicola".
534:
659:–dependent enzyme catalyzes rearrangement of L-methylmalonyl-CoA to succinyl-CoA, which is an intermediate of the citric acid cycle and can be readily incorporated there.
476:
484:
320:
1111:
775:
728:
498:
100:
1004:
491:
744:
Center for Food and
Nutrition Policy review of use of calcium propanoate as an organic agent in cow feed and as milk fever prevention
655:. In most vertebrates, propionyl-CoA is carboxylated to D-methylmalonyl-CoA, which is isomerised to L-methylmalonyl-CoA. A vitamin B
285:
800:
1104:
541:
228:
1986:
1981:
249:
1976:
1097:
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S. Dengate; A. Rubin (2002). "Controlled trial of cumulative behavioural effects of a common bread preservative".
1749:
150:
779:
1084:
743:
725:
1031:"Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism"
138:
1887:
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1422:
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627:
1971:
1935:
1610:
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667:) and brain changes (e.g. innate neuroinflammation, glutathione depletion) partially mimicking human
36:
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66:
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872:
Furia, T. E. (1973). CRC Handbook of Food
Additives. CRC Handbook of Food Additives. CRC Press.
824:
Furia, T. E. (1973). CRC Handbook of Food
Additives. CRC Handbook of Food Additives. CRC Press.
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384:
131:
911:
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217:
23:
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1005:"OPP PESTICIDE ECOTOXICITY DATABASE - Details - Pesticide: Calcium propionate"
939:
615:
408:
366:
111:
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776:"NYSAES|FST|FVC|Venture 3| Chemical Food Preservatives"
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Haghikia, Arash; Zimmermann, Friederike; Schumann, Paul (7 Feb 2022).
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Except where otherwise noted, data are given for materials in their
834:
Thompson, Jackie M.; Dodd, Christine E.R.; Waites, Will M. (1993).
192:
99:
89:
1085:
Center for
Science in the Public Interest list of food additives
183:
1093:
294:
InChI=1S/2C3H6O2.Ca/c2*1-2-3(4)5;/h2*2H2,1H3,(H,4,5);/q;;+2/p-2
678:
304:
InChI=1/2C3H6O2.Ca/c2*1-2-3(4)5;/h2*2H2,1H3,(H,4,5);/q;;+2/p-2
254:
468:
685:
of calcium propionate was found to be slightly toxic to
674:
Calcium propionate can be used as a fungicide on fruit.
529:
169:
1642:
1603:
1479:
1313:
1239:
1127:
840:
216:
472:
75:
726:Codex Alimentarius data for calcium propanoate
1105:
8:
681:, the waterborne administration of 180
267:DTXSID90904548 DTXSID1027556, DTXSID90904548
1112:
1098:
1090:
269:
141:
119:
15:
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236:
884:Journal of Paediatrics and Child Health
702:
325:
290:
265:
132:
297:Key: BCZXFFBUYPCTSJ-UHFFFAOYSA-L
7:
606:As a food additive, it is listed as
1007:. EPA / USDA / NIFA. Archived from
756:"Ingredients -- Calcium propionate"
307:Key: BCZXFFBUYPCTSJ-NUQVWONBAE
207:
191:
14:
896:10.1046/j.1440-1754.2002.00009.x
801:"Keeping molds, bacteria at bay"
677:In a 1973 study reported by the
519:
22:
836:"Spoilage of bread by bacillus"
515:(at 25 °C , 100 kPa).
1:
860:10.1016/0964-8305(93)90039-5
371:186.2192 g/mol
635:are effective against both
2003:
983:10.1094/PDIS.1997.81.4.399
928:Behavioural Brain Research
1047:10.1093/eurheartj/ehab644
940:10.1016/j.bbr.2006.07.025
509:
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35:
30:
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379:White crystalline solid
1128:Hydrogen & halogens
403:55.8 g/100 mL (100 °C)
1035:European Heart Journal
479:
926:spectrum disorders".
628:Bacillus mesentericus
478:
461:(fire diamond)
413:slightly soluble in
52:Calcium dipropionate
41:Calcium dipropanoate
37:Preferred IUPAC name
852:1993IBiBi..32...55T
625:A few decades ago,
401:49 g/100 mL (0 °C)
396:Solubility in water
18:
17:Calcium propanoate
1987:E-number additives
1982:Food preservatives
731:2006-10-21 at the
653:citric acid cycles
612:Codex Alimentarius
558:calcium propionate
554:Calcium propanoate
542:Infobox references
480:
50:Calcium propionate
16:
1977:Calcium compounds
1959:
1958:
1480:Group 13 & 14
1121:Calcium compounds
633:sodium propionate
550:Chemical compound
548:
547:
441:Crystal structure
250:CompTox Dashboard
101:Interactive image
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803:. Archived from
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778:. Archived from
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712:, 11th Edition,
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560:has the formula
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344:Chemical formula
328:CCC(=O).CCC(=O).
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639:rope and mold.
637:B. mesentericus
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1079:External links
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642:Metabolism of
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1011:on 2019-01-23
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60:Identifiers
48:Other names
1972:Propionates
710:Merck Index
610:282 in the
446:monoclinic
376:Appearance
337:Properties
139:100.021.633
1966:Categories
1314:Pnictogens
1240:Chalcogens
1015:2019-01-22
811:2007-03-24
786:2010-02-28
761:2007-03-10
697:References
644:propionate
616:milk fever
434:Structure
409:Solubility
367:Molar mass
238:8AI80040KW
112:ChemSpider
88:3D model (
67:CAS Number
160:223-795-8
152:EC Number
77:4075-81-4
1643:Organics
1065:34597388
991:30861823
948:16950524
912:24898218
904:12173999
729:Archived
608:E number
594:salt of
458:NFPA 704
451:Hazards
415:methanol
170:E number
1159:Ca(ClO)
1056:9097250
956:3054752
848:Bibcode
651:or the
592:calcium
535:what is
533: (
428:benzene
424:acetone
419:ethanol
389:300 °C
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205:PubChem
54:Mycoban
1662:Ca(HCO
1611:Ca(MnO
1519:Ca(HCO
1495:Ca(CN)
1260:Ca(OH)
1199:Ca(BrO
1179:Ca(ClO
1167:Ca(ClO
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669:autism
530:verify
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321:SMILES
193:D09875
31:Names
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1631:CaTiO
1623:CaCrO
1415:CaHPO
1353:Ca(NO
1341:Ca(NO
1219:Ca(IO
952:S2CID
908:S2CID
286:InChI
218:19999
175:E282
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1503:CaCN
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1151:CaCl
1061:PMID
987:PMID
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900:PMID
714:1705
602:Uses
229:UNII
184:KEGG
1948:CaO
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1880:CaO
1860:CaN
1828:CaC
1815:CaN
1758:CaO
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1650:CaC
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