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479:
474:
24:
579:
487:
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696:
moved to ban its use in pork, citing a potential cancer risk to humans. However, as of August 2018, FDA had indefinitely stayed its withdrawal of approval and carbadox remains available.
592:
707:
feed additive and for human consumption. The
European Union also forbids the use of carbadox at any level. Australia forbids the use of carbadox in food producing animals.
98:
339:
634:
Carbadox is indicated for control of swine dysentery (vibrionic dysentery, bloody scours, or hemorrhagic dysentery); control of bacterial swine
525:
811:
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907:
304:
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944:
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and may not be used within 42 days of slaughter or used in pregnant animals. In 2016, the United States
501:
466:
138:
36:
676:'s Center for Veterinary Medicine has questioned the safety in light of its possible carcinogenicity.
959:
700:
644:
541:
313:
InChI=1S/C11H10N4O4/c1-19-11(16)13-12-6-8-7-14(17)9-4-2-3-5-10(9)15(8)18/h2-7H,1H3,(H,13,16)/b12-6+
285:
64:
529:
323:
InChI=1/C11H10N4O4/c1-19-11(16)13-12-6-8-7-14(17)9-4-2-3-5-10(9)15(8)18/h2-7H,1H3,(H,13,16)/b12-6+
858:
770:
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438:
362:
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656:
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74:
913:
289:
180:
118:
570:
766:
220:
933:
685:
639:
427:
169:
561:
669:
650:
537:
672:, carbadox has been shown to be carcinogenic and to induce birth defects. The
396:
149:
704:
648:); aid in the prevention of migration and establishment of large roundworm (
635:
623:
774:
912:, Australian Pesticides and Veterinary Medicines Authority, archived from
909:
Substances Not
Permitted for use on Food-Producing Animals in Australia
753:
Yoshimura, Haruo (2002). "Teratogenic assessment of carbadox in rats".
417:
207:
189:
654:) infections; aid in the prevention of establishment of nodular worm (
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Except where otherwise noted, data are given for materials in their
511:
23:
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109:
97:
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507:
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273:
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882:"WHO Food Additives Series: 51 CARBADOX (addendum)"
812:"FDA Moves to Ban Cancer-Causing Pork Antibiotic"
219:
73:
791:. Food and Drug Administration. July 31, 2019
8:
432:239.5 °C (463.1 °F; 512.6 K)
789:"Questions and Answers regarding Carbadox"
288:
179:
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15:
255:
716:
344:
309:
284:
170:
722:
720:
316:Key: OVGGLBAWFMIPPY-WUXMJOGZSA-N
137:
117:
7:
699:In 2004, carbadox was banned by the
326:Key: OVGGLBAWFMIPPY-WUXMJOGZBN
210:
14:
837:"10-K: PHIBRO ANIMAL HEALTH CORP"
642:or necrotic enteritis caused by
577:
477:
472:
380:
374:
22:
573:(at 25 °C , 100 kPa).
386:
368:
1:
767:10.1016/S0378-4274(01)00522-7
810:Fox, Maggie (8 April 2016).
694:Food and Drug Administration
684:Carbadox is approved in the
674:Food and Drug Administration
863:, Health Canada, 2003-05-15
732:Code of Federal Regulations
347:COC(=O)N\N=C\c2c()c1ccccc12
986:
618:that combats infection in
886:WHO Food Additives Series
567:
453:
448:
355:
335:
300:
57:
49:
35:
30:
21:
520:Precautionary statements
44:)-2-hydrazinecarboxylate
860:Maximum Residue Limits
622:, particularly swine
945:Antiparasitic agents
880:Ungemach, Fritz R.
701:Canadian government
645:Salmonella enterica
439:Solubility in water
404: g·mol
18:
755:Toxicology Letters
600:Infobox references
16:
734:. FDA. 1 Apr 2014
608:Chemical compound
606:
605:
502:Hazard statements
269:CompTox Dashboard
99:Interactive image
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965:Veterinary drugs
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761:(1–2): 115–118.
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688:only for use in
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363:Chemical formula
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728:"21CFR 558.115"
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666:
657:Oesophagostomum
632:
616:veterinary drug
609:
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595: ?)
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5:
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940:Antimicrobials
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660:) infections.
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571:standard state
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40:Methyl (2
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10:
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2:
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970:Methyl esters
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916:on 2011-02-22
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839:. MarketWatch
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686:United States
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670:animal models
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640:salmonellosis
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428:Melting point
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171:ECHA InfoCard
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955:Amine oxides
950:Quinoxalines
918:, retrieved
914:the original
908:
902:
890:. Retrieved
885:
875:
865:, retrieved
859:
853:
841:. Retrieved
831:
819:. Retrieved
815:
805:
793:. Retrieved
783:
758:
754:
748:
736:. Retrieved
731:
698:
683:
667:
655:
651:Ascaris suum
649:
643:
633:
611:
610:
493:
455:
232:RTECS number
58:Identifiers
50:Other names
41:
630:Indications
488:Signal word
409:Appearance
356:Properties
177:100.027.163
139:ChEMBL13779
119:CHEBI:94744
960:Hydrazones
934:Categories
920:2010-08-31
867:2010-07-27
711:References
680:Regulation
467:Pictograms
444:Insoluble
422:1.44 g/cm
397:Molar mass
257:M2X04R2E2Y
150:ChemSpider
86:3D model (
65:CAS Number
37:IUPAC name
795:August 7,
705:livestock
636:enteritis
624:dysentery
558:P370+P378
550:P301+P312
458:labelling
239:FE2779000
221:135403805
198:229-879-0
190:EC Number
75:6804-07-5
17:Carbadox
888:. INCHEM
816:NBC News
775:11879981
612:Carbadox
449:Hazards
159:10606106
593:what is
591: (
494:Warning
418:Density
402:262.225
208:PubChem
52:Mecadox
892:23 Mar
773:
738:23 Mar
664:Safety
588:verify
585:
340:SMILES
130:ChEMBL
31:Names
843:3 Jul
821:9 Apr
703:as a
690:swine
620:swine
614:is a
305:InChI
110:ChEBI
88:JSmol
894:2015
845:2019
823:2016
797:2019
771:PMID
740:2015
562:P501
554:P330
546:P280
542:P270
538:P264
534:P241
530:P240
526:P210
512:H302
508:H228
248:UNII
763:doi
759:129
668:In
456:GHS
274:EPA
211:CID
936::
884:.
814:.
769:.
757:.
730:.
719:^
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638:(
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387:O
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369:C
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272:(
90:)
42:E
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