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The first patient to receive the plastic implant had rheumatic fever, which had severely damaged her aortic valve to the point where she was given little chance to live. Shortly after the implant, she was able to resume a normal life and lived for almost a decade with the implanted valve before dying
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September 1952 Hufnagel, then director of the Georgetown University Medical Center's surgical research laboratory, implanted an aortic "assist" valve into the circulatory system of a 30-year-old woman. The valve consisted of a pea-size ball of plastic inside a chambered tube—an inch and a half
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The panel determined that Nixon was too ill to testify for at least six weeks. But the medical doctors made a point of protecting the confidentiality of the
President's medical records and refused to cite a reason for recommending against his testifying. Nixon never testified.
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long and an inch thick—that regulated blood flow through the heart. The manufactured valve compensated for the faulty original valve, but did not actually replace it, while ensuring that the heart was able to pump blood successfully into the body's circulatory system.
171:, he began work on the heart and other organ transplants and explored the use of plastic to replace blood vessels, developing a technique called multi-point fixation, which would have great importance in the placement of the artificial aortic valve.
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of unrelated causes. The valve itself, however, had some drawbacks, including the fact that it "clicked" loudly enough to be heard by others. Several hundred other patients subsequently received other "Hufnagel" valves.
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Hufnagel was a member of more than 75 surgical and academic societies in the United States, Europe and South
America. He was the author of more than 400 articles in medical and other scientific journals.
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Hufnagel later made significant contributions to the development of the modern heart-lung machine. The principle of the early artificial aortic valve still serves as a model for heart implants.
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faculty as director of the surgical research laboratory and professor of surgery. He became chairman of the department of surgery in 1969 and held the post until 1979.
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The purpose of the aortic valve is to prevent blood from flowing backward into the heart. In the artificial valve the free-moving plastic
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in the tube was dislodged by the pulsing blood with each heartbeat, then fell back to close the tube between pulses.
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In 1974, Hufnagel served as chairman of a three-member medical panel that evaluated the condition of
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Hufnagel
Artificial Heart Valve in the collection of the National Museum of Health and Medicine.
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144:(August 15, 1916 – May 31, 1989) was an American surgeon who invented the first
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285:"Charles A. Hufnagel, 72, Surgeon Who Invented Plastic Heart Valve"
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He died in
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159:. His father was also a surgeon. He graduated from the
259:"Hufnagel's Valve | the Artificial Heart Valve"
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http://www.ajronline.org/cgi/reprint/139/5/1010.pdf
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218:Among the awards and honors he received were the
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163:and earned his medical degree from
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174:In 1950, Hufnagel joined the
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