453:
33:
1578:
Hsu, Jer-Yuan; Sun, Zu-Wen; Li, Xiumin; Reuben, Melanie; Tatchell, Kelly; Bishop, Douglas K.; Grushcow, Jeremy M.; Brame, Cynthia J.; Caldwell, Jennifer A.; Hunt, Donald F.; Lin, Rueyling; Smith, M. Mitchell; Allis, C. David (2000).
1128:
4243:
1460:
Mizzen, Craig A.; Yang, Xiang-Jiao; Kokubo, Tetsuro; Brownell, James E.; Bannister, Andrew J.; Owen-Hughes, Tom; Workman, Jerry; Wang, Lian; Berger, Shelley L.; Kouzarides, Tony; Nakatani, Yoshihiro; Allis, C. David (1996).
4193:
1704:
Strahl, Brian D.; Grant, Patrick A.; Briggs, Scott D.; Sun, Zu-Wen; Bone, James R.; Caldwell, Jennifer A.; Mollah, Sahana; Cook, Richard G.; Shabanowitz, Jeffrey; Hunt, Donald F.; Allis, C. David (2002).
1526:"Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation"
4188:
2570:
4233:
1139:
2398:
728:
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Nacev, Benjamin A.; Feng, Lijuan; Bagert, John D.; Lemiesz, Agata E.; Gao, JianJiong; Soshnev, Alexey A.; Kundra, Ritika; Schultz, Nikolaus; Muir, Tom W.; Allis, C. David (2019).
2338:
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1663:
Rice, Judd C.; Briggs, Scott D.; Ueberheide, Beatrix; Barber, Cynthia M.; Shabanowitz, Jeffrey; Hunt, Donald F.; Shinkai, Yoichi; Allis, C. David (2003).
2752:
702:
1524:
Hendzel, Michael J.; Wei, Yi; Mancini, Michael A.; Van Hooser, Aaron; Ranalli, Tamara; Brinkley, B. R.; Bazett-Jones, David P.; Allis, C. David (1997).
2331:
614:
stimulation, and established a synergistic relationship between histone phosphorylation and acetylation. He also determined the role of methylation at
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Brownell, James E.; Zhou, Jianxin; Ranalli, Tamara; Kobayashi, Ryuji; Edmondson, Diane G.; Roth, Sharon Y.; Allis, C. David (1996).
579:
Following this seminal report, Allis continued studying histone acetylation, discovering more histone acetyltransferases, including
4228:
3916:
2544:
1581:"Mitotic Phosphorylation of Histone H3 Is Governed by Ipl1/aurora Kinase and Glc7/PP1 Phosphatase in Budding Yeast and Nematodes"
750:
137:
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1622:"Synergistic Coupling of Histone H3 Phosphorylation and Acetylation in Response to Epidermal Growth Factor Stimulation"
4104:
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1129:"A Tribute to C. David Allis, PhD — Professor in the Department of Biochemistry and Molecular Genetics from 1998-2003"
787:
153:
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573:
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1266:"Tetrahymena Histone Acetyltransferase A: A Homolog to Yeast Gcn5p Linking Histone Acetylation to Gene Activation"
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90:
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Cheung, Peter; Tanner, Kirk G.; Cheung, Wang L.; Sassone-Corsi, Paolo; Denu, John M.; Allis, C. David (2000).
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2402:
1665:"Histone Methyltransferases Direct Different Degrees of Methylation to Define Distinct Chromatin Domains"
2279:
1964:
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1707:"Set2 Is a Nucleosomal Histone H3-Selective Methyltransferase That Mediates Transcriptional Repression"
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1362:"Acetylation and methylation of histones and their possible role in the regulation of rna synthesis"
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1421:"Pursuing the Secrets of Histone Proteins: An Amazing Journey with a Remarkable Supporting Cast"
531:. Chromatin biology at the time was not a popular topic; nor was the use of ciliated organisms.
462:
403:
Professor of
Biology two years later. In 1998, Allis went to the Department of Biochemistry and
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970:
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243:
103:
2220:
1960:"Covalent histone modifications — miswritten, misinterpreted and mis-erased in human cancers"
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In more recent years, his attention turned to "oncohistones", which are histones with
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2813:
2571:"2017 March of Dimes Prize awarded to Dr. C. David Allis for groundbreaking research"
2216:
2168:
2052:
684:
291:
2372:
1760:"Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast"
1725:
1557:
4027:
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2276:"C. David Allis to Receive the Third Annual Wiley Prize in the Biomedical Sciences"
2253:
1936:
1932:
1863:
1801:
1199:
690:
657:, and recognized the clinical significance of histone modifications, especially in
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Isolation and characterization of pole cells and polar granules from embryos of
170:
133:
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2010:
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1420:
572:, verifying Vincent Allfrey's hypothesis in the 1960s that histone acetylation
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1183:
623:
619:
433:
Allis had been treated for cancer. He died
January 8, 2023, at a hospital in
3912:
3773:
3749:
3510:
3441:
2950:
2884:
2151:
2124:
1916:
1327:
1031:
631:
562:. This was the first time that histone acetyltransferases were connected to
496:
480:
423:
378:
255:
32:
2160:
2109:
2044:
1995:
1924:
1855:
1793:
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1606:
1446:
1405:
1346:
1191:
1050:
898:"David Allis, researcher who explored 'on-off' switch in genes, dies at 71"
1549:
1541:
1495:
1386:
1293:
739:
Lewis S. Rosenstiel Award for
Distinguished Work in Basic Medical Research
3550:
2807:
665:
528:
1823:
1785:
646:
611:
607:
603:
599:
547:
504:
490:
476:
382:
306:
298:
209:
205:
119:
2660:"2022 Albany Prize Awarded for Pivotal Discoveries in Gene Regulation"
3178:
2068:"The expanding landscape of 'oncohistone' mutations in human cancers"
658:
615:
543:
199:
1977:
2485:"Lauréat 2014 du prix Charles-Léopold Mayer : C. David Allis"
1847:
559:
4244:
Recipients of the Albert Lasker Award for Basic
Medical Research
3010:
580:
287:
57:
3554:
2741:
805:
The C. David Allis
Mentorship Fund for Young Scientists at the
668:
that distort normal histone modifications, leading to cancers.
563:
1467:
250 Subunit of TFIID Has
Histone Acetyltransferase Activity"
321:. The experience attracted him to research, and he went to
2692:. Rockefeller University. January 14, 2023. Archived from
4194:
Members of the United States
National Academy of Sciences
2399:
American
Society for Biochemistry and Molecular Biology
729:
American
Society for Biochemistry and Molecular Biology
598:
transcription). Allis also branched off to researching
2716:"C. David Allis Mentorship Fund for Young Scientists"
1229:"2014 Japan Prize Achievement - "Life Science" field"
4189:
Fellows of the
American Academy of Arts and Sciences
2278:. Wiley Foundation. January 27, 2004. Archived from
1958:
Chi, Ping; Allis, C. David; Wang, Gang Greg (2010).
1360:
Allfrey, V. G.; Faulkner, R.; Mirsky, A. E. (1964).
4079:
3940:
3805:
3670:
3589:
3216:
2869:
2776:
242:(March 22, 1951 – January 8, 2023) was an American
221:
198:
176:
166:
125:
114:
86:
64:
39:
23:
1099:"C. David Allis Named Wilson Professor of Biology"
4234:University of Virginia School of Medicine faculty
2601:"2018 Albert Lasker Basic Medical Research Award"
1824:"The language of covalent histone modifications"
1309:""Modifying" My Career toward Chromatin Biology"
1161:Goldfarb, David S.; Gorovsky, Martin A. (2009).
1066:"Former SU professor named Japan Prize Laureate"
399:in 1995, and became the Marie Curran Wilson and
2332:"Past A&S Alumni Award Winners (2002-2019)"
1366:Proceedings of the National Academy of Sciences
1010:Proceedings of the National Academy of Sciences
775:Albert Lasker Award for Basic Medical Research
653:) explicitly associated the histone code with
637:In 2000, Allis and Brian Strahl proposed the "
150:Albert Lasker Award for Basic Medical Research
3566:
2753:
769:March of Dimes Prize in Developmental Biology
8:
2690:"Remembering a pioneer of chromatin biology"
931:
929:
927:
925:
854:
852:
827:"Alum C. David Allis wins 2018 Lasker Award"
333:three years later, under the supervision of
254:. He was also the Head of the Laboratory of
4239:Members of the National Academy of Medicine
1093:
1091:
325:for graduate studies. He graduated with an
3573:
3559:
3551:
2760:
2746:
2738:
1822:Strahl, Brian D.; Allis, C. David (2000).
31:
20:
3145:The Event Horizon Telescope Collaboration
2243:"Massry Prize Winners ( 1996 – Present )"
2150:
2099:
2034:
1985:
1906:
1734:
1724:
1680:
1639:
1596:
1485:
1436:
1395:
1385:
1336:
1326:
1283:
1040:
1030:
2718:. Rockefeller University. Archived from
422:Professor and Head of the Laboratory of
16:American molecular biologist (1951–2023)
1163:"Nuclear Dimorphism: Two Peas in a Pod"
818:
723:Gairdner Foundation International Award
606:. He linked histone phosphorylation to
998:
996:
994:
992:
891:
889:
887:
268:Memorial Sloan Kettering Cancer Center
266:(the other two institutions being the
4204:Indiana University Bloomington alumni
2187:American Academy of Arts and Sciences
1758:Sun, Zu-Wen; Allis, C. David (2002).
679:American Academy of Arts and Sciences
527:that is transcriptionally silent and
381:in 1989. He joined the Department of
7:
833:. September 11, 2018. Archived from
475:Allis was known for his research of
2547:. Gruber Foundation. Archived from
2009:Dent, Sharon; Grewal, Shiv (2023).
1064:Scalese, Sarah (February 4, 2014).
937:"C. David Allis, Ph.D. (1951-2023)"
757:Breakthrough Prize in Life Sciences
641:hypothesis", which states that DNA
142:Breakthrough Prize in Life Sciences
130:Canada Gairdner International Award
4224:Baylor College of Medicine faculty
2666:. October 13, 2022. Archived from
1138:. January 24, 2023. Archived from
896:Murphy, Brian (January 21, 2023).
868:. January 14, 2023. Archived from
697:Wiley Prize in Biomedical Sciences
554:to Gcn5p, a known transcriptional
14:
2247:University of Southern California
483:structure. He started working on
309:. He had his first experience of
751:Grand Prix Charles-Leopold Mayer
534:In 1996, his group isolated the
451:
264:Tri-Institutional MD–PhD Program
138:Grand Prix Charles-Leopold Mayer
4209:University of Rochester faculty
4199:University of Cincinnati alumni
4000:/ John Frederick Grassle (2013)
1726:10.1128/MCB.22.5.1298-1306.2002
1314:Journal of Biological Chemistry
1105:. July 25, 1997. Archived from
634:regulates histone methylation.
503:is an ideal candidate to study
4214:Rockefeller University faculty
1889:"Translating the histone code"
1712:Molecular and Cellular Biology
860:"Charles David Allis ("Dave")"
831:Indiana University Bloomington
809:was established in his honor.
649:. Later, Allis (together with
323:Indiana University Bloomington
1:
4184:American molecular biologists
3710:Ernest John Christopher Polge
2577:. May 8, 2017. Archived from
1682:10.1016/s1097-2765(03)00479-9
1641:10.1016/s1097-2765(00)80256-7
1598:10.1016/S0092-8674(00)00034-9
1487:10.1016/S0092-8674(00)81821-8
1285:10.1016/S0092-8674(00)81063-6
712:Distinguished Alumnus Award,
282:Allis was born and raised in
3053:Sudbury Neutrino Observatory
2634:National Academy of Medicine
2339:College of Arts and Sciences
2306:National Academy of Sciences
2125:"C. David Allis (1951–2023)"
2011:"C. David Allis (1951–2023)"
782:National Academy of Medicine
717:College of Arts and Sciences
707:National Academy of Sciences
390:College of Arts and Sciences
4219:Syracuse University faculty
2977:Supernova Cosmology Project
2213:"2002 Dickson Prize Winner"
2123:Berger, Shelley L. (2023).
1005:"Profile of C. David Allis"
798:when he graduated from the
788:Albany Medical Center Prize
550:, and found the enzyme was
154:Albany Medical Center Prize
4260:
4179:Scientists from Cincinnati
2489:French Academy of Sciences
2036:10.1038/d41586-023-00346-0
1887:; Allis, C. David (2001).
1438:10.1016/j.cell.2018.08.022
359:Baylor College of Medicine
193:Baylor College of Medicine
3726:William Hayward Pickering
3601:Ephraim Katchalski-Katzir
2092:10.1038/s41586-019-1038-1
1184:10.1016/j.cub.2009.04.023
829:. Department of Biology,
685:Dickson Prize in Medicine
630:, and found that histone
628:histone methyltransferase
536:histone acetyltransferase
401:Joseph Chamberlain Wilson
357:. In 1981, he joined the
262:, and a professor at the
233:
159:
30:
2519:Breakthrough Prize Board
2336:University of Cincinnati
1419:Allis, C. David (2018).
1307:Allis, C. David (2015).
800:University of Cincinnati
763:Gruber Prize in Genetics
714:University of Cincinnati
645:is largely regulated by
626:-containing proteins as
303:University of Cincinnati
278:Early life and education
146:Gruber Prize in Genetics
91:University of Cincinnati
4229:Massry Prize recipients
3867:/ Keith J. Sainsbury /
3471:Shankar Balasubramanian
3207:Alexander Zamolodchikov
3139:Peter van Nieuwenhuizen
2631:"C. David Allis, Ph.D."
2250:Keck School of Medicine
2152:10.1126/science.adg7738
1917:10.1126/science.1063127
1328:10.1074/jbc.X115.663229
1103:University of Rochester
1032:10.1073/pnas.0602256103
1003:Downey, Philip (2006).
865:The Cincinnati Enquirer
600:histone phosphorylation
418:in 2003 as the Joy and
397:University of Rochester
351:University of Rochester
347:postdoctoral fellowship
210:Drosophila melanogaster
189:University of Rochester
4038:Emmanuelle Charpentier
3657:Frank Sherwood Rowland
3485:Clifford P. Brangwynne
3318:Emmanuelle Charpentier
2664:Albany Medical College
2455:"The 2014 Japan Prize"
1133:University of Virginia
941:Rockefeller University
807:Rockefeller University
794:Allis was a member of
479:and their relation to
416:Rockefeller University
409:University of Virginia
395:Allis returned to the
373:, and was promoted to
272:Weill Cornell Medicine
252:Rockefeller University
185:University of Virginia
181:Rockefeller University
2989:High-Z Supernova Team
1965:Nature Reviews Cancer
1542:10.1007/s004120050256
1387:10.1073/pnas.51.5.786
647:histone modifications
477:histone modifications
365:in the Department of
305:in 1969, majoring in
120:histone modifications
4143:John Michael Wallace
3428:Virginia Man-Yee Lee
3292:Alexander Varshavsky
3111:Jocelyn Bell Burnell
3009:and contributors to
2722:on February 16, 2023
2696:on February 16, 2023
2223:on December 25, 2022
1939:on February 20, 2023
1245:on February 15, 2023
1209:on February 14, 2023
1142:on February 11, 2023
585:transcription factor
464:Charles David Allis
353:after obtaining his
317:(or fourth) year of
4127:/ Kazuo Hagimoto /
3966:Tadamitsu Kishimoto
3696:Jacques-Louis Lions
3412:Jeffrey M. Friedman
3302:Charles David Allis
2987:and members of the
2975:and members of the
2670:on October 14, 2022
2640:on February 8, 2023
2611:on February 8, 2023
2581:on February 8, 2023
2551:on February 1, 2023
2525:on January 16, 2023
2495:on February 7, 2023
2465:on February 2, 2023
2435:on February 6, 2023
2429:Brandeis University
2405:on February 6, 2023
2395:"ASBMB–Merck Award"
2375:on December 6, 2021
2369:Gairdner Foundation
2345:on December 4, 2022
2312:on February 5, 2023
2282:on February 5, 2023
2256:on December 5, 2022
2193:on February 3, 2023
2143:2023Sci...379..645B
2084:2019Natur.567..473N
2027:2023Natur.614..409D
1901:(5532): 1074–1080.
1840:2000Natur.403...41S
1786:10.1038/nature00883
1778:2002Natur.418..104S
1378:1964PNAS...51..786A
1321:(26): 15904–15908.
1109:on October 16, 2019
1076:on October 19, 2021
1070:Syracuse University
1023:2006PNAS..103.6425D
977:on February 7, 2023
947:on January 30, 2023
910:on January 23, 2023
903:The Washington Post
872:on January 17, 2023
837:on February 1, 2023
604:histone methylation
505:histone acetylation
387:Syracuse University
375:associate professor
363:assistant professor
319:Bachelor of Science
290:. His father was a
244:molecular biologist
240:Charles David Allis
25:Charles David Allis
4105:Robert A. Weinberg
4087:Robert G. Gallager
4032:Steven D. Tanksley
4018:Theodore Friedmann
3921:Victor A. McKusick
3879:Masatoshi Takeichi
3827:Timothy R. Parsons
3823:John B. Goodenough
3817:Kimishige Ishizaka
3792:Jack L. Strominger
3788:W. Wesley Peterson
3768:Hiroyuki Yoshikawa
3764:Joseph Engelberger
3740:Edward F. Knipling
3505:Masashi Yanagisawa
3416:Franz-Ulrich Hartl
3346:Stephen J. Elledge
3298:Alim Louis Benabid
3185:Charles H. Bennett
3135:Daniel Z. Freedman
3085:Charles L. Bennett
3049:Arthur B. McDonald
3037:KĹŤichirĹŤ Nishikawa
2967:John Henry Schwarz
2957:Alexander Polyakov
2935:Michel Della Negra
2854:Daniel A. Spielman
2769:Breakthrough Prize
1136:School of Medicine
511:. It has a larger
461:has a profile for
412:School of Medicine
405:Molecular Genetics
369:and Department of
345:Allis undertook a
294:and his mother an
246:, and the Joy and
100:Indiana University
4156:
4155:
4125:Masataka Nakazawa
4119:Christopher Field
4004:Yasuharu Suematsu
3948:Shun-ichi Iwasaki
3907:Peter Shaw Ashton
3847:Benoit Mandelbrot
3841:Andrzej Tarkowski
3661:Elias James Corey
3548:
3547:
3527:Fredrick Van Goor
3420:Arthur L. Horwich
3394:Adrian R. Krainer
3288:Richard P. Lifton
3246:Napoleone Ferrara
3226:Cornelia Bargmann
3075:Andrew Strominger
3071:Joseph Polchinski
2881:Nima Arkani-Hamed
2830:Vincent Lafforgue
2820:Christopher Hacon
2662:(Press release).
2605:Lasker Foundation
2078:(7749): 473–478.
1772:(6893): 104–108.
1505:on April 15, 2019
1178:(11): R449–R452.
1017:(17): 6425–6427.
971:Gruber Foundation
672:Honors and awards
517:transcriptionally
467:
301:. He entered the
296:elementary school
250:Professor at the
237:
236:
161:Scientific career
4251:
3994:C. Grant Willson
3782:Marc Van Montagu
3756:Takashi Sugimura
3690:Xavier Le Pichon
3635:Donald Henderson
3631:Georges Vendryes
3575:
3568:
3561:
3552:
3539:Andrew Singleton
3489:Anthony A. Hyman
3459:Jeffery W. Kelly
3454:
3446:Richard J. Youle
3390:C. Frank Bennett
3384:Don W. Cleveland
3358:Yoshinori Ohsumi
3284:Robert S. Langer
3272:James P. Allison
3234:Lewis C. Cantley
3175:Hidetoshi Katori
3155:Jens H. Gundlach
3065:Super-Kamiokande
2947:Joseph Incandela
2931:Fabiola Gianotti
2893:Maxim Kontsevich
2848:Takuro Mochizuki
2790:Maxim Kontsevich
2762:
2755:
2748:
2739:
2732:
2731:
2729:
2727:
2712:
2706:
2705:
2703:
2701:
2686:
2680:
2679:
2677:
2675:
2656:
2650:
2649:
2647:
2645:
2636:. Archived from
2627:
2621:
2620:
2618:
2616:
2607:. Archived from
2597:
2591:
2590:
2588:
2586:
2567:
2561:
2560:
2558:
2556:
2545:"C. David Allis"
2541:
2535:
2534:
2532:
2530:
2521:. Archived from
2515:"C. David Allis"
2511:
2505:
2504:
2502:
2500:
2491:. Archived from
2481:
2475:
2474:
2472:
2470:
2461:. Archived from
2451:
2445:
2444:
2442:
2440:
2431:. Archived from
2421:
2415:
2414:
2412:
2410:
2401:. Archived from
2391:
2385:
2384:
2382:
2380:
2371:. Archived from
2365:"C. David Allis"
2361:
2355:
2354:
2352:
2350:
2341:. Archived from
2328:
2322:
2321:
2319:
2317:
2308:. Archived from
2302:"C. David Allis"
2298:
2292:
2291:
2289:
2287:
2272:
2266:
2265:
2263:
2261:
2252:. Archived from
2239:
2233:
2232:
2230:
2228:
2219:. Archived from
2209:
2203:
2202:
2200:
2198:
2189:. Archived from
2183:"C. David Allis"
2179:
2173:
2172:
2154:
2120:
2114:
2113:
2103:
2063:
2057:
2056:
2038:
2006:
2000:
1999:
1989:
1955:
1949:
1948:
1946:
1944:
1935:. Archived from
1910:
1885:Jenuwein, Thomas
1881:
1875:
1874:
1872:
1870:
1819:
1813:
1812:
1810:
1808:
1755:
1749:
1748:
1738:
1728:
1719:(5): 1298–1306.
1701:
1695:
1694:
1684:
1675:(6): 1591–1598.
1660:
1654:
1653:
1643:
1617:
1611:
1610:
1600:
1575:
1569:
1568:
1566:
1564:
1521:
1515:
1514:
1512:
1510:
1504:
1498:. Archived from
1489:
1480:(7): 1261–1270.
1471:
1457:
1451:
1450:
1440:
1416:
1410:
1409:
1399:
1389:
1357:
1351:
1350:
1340:
1330:
1304:
1298:
1297:
1287:
1261:
1255:
1254:
1252:
1250:
1244:
1238:. Archived from
1233:
1225:
1219:
1218:
1216:
1214:
1208:
1202:. Archived from
1167:
1158:
1152:
1151:
1149:
1147:
1125:
1119:
1118:
1116:
1114:
1095:
1086:
1085:
1083:
1081:
1072:. Archived from
1061:
1055:
1054:
1044:
1034:
1000:
987:
986:
984:
982:
973:. Archived from
967:"C. David Allis"
963:
957:
956:
954:
952:
943:. Archived from
933:
920:
919:
917:
915:
906:. Archived from
893:
882:
881:
879:
877:
856:
847:
846:
844:
842:
823:
546:that acetylates
523:, and a smaller
465:
455:
454:
414:. He joined the
335:Anthony Mahowald
228:Anthony Mahowald
223:Doctoral advisor
217:
71:
49:
47:
35:
21:
4259:
4258:
4254:
4253:
4252:
4250:
4249:
4248:
4159:
4158:
4157:
4152:
4147:Ronald M. Evans
4133:Karl Deisseroth
4129:Gero Miesenböck
4101:Bert Vogelstein
4097:Martin A. Green
4075:
4056:Max Dale Cooper
4042:Jennifer Doudna
4014:Yutaka Takahasi
3936:
3883:Erkki Ruoslahti
3865:Akira Fujishima
3833:Tim Berners-Lee
3801:
3796:Don Craig Wiley
3682:W. Jason Morgan
3666:
3625:Theodore Maiman
3611:Willem J. Kolff
3585:
3579:
3549:
3544:
3535:Ellen Sidransky
3515:Michel Sadelain
3501:Emmanuel Mignot
3475:David Klenerman
3448:
3438:Catherine Dulac
3350:Harry F. Noller
3328:Karl Deisseroth
3314:Jennifer Doudna
3280:Michael N. Hall
3266:Bert Vogelstein
3262:Shinya Yamanaka
3258:Robert Weinberg
3254:Charles Sawyers
3212:
3189:Gilles Brassard
3169:Steven Weinberg
3151:Eric Adelberger
3061:YĹŤichirĹŤ Suzuki
2973:Saul Perlmutter
2939:Tejinder Virdee
2923:Stephen Hawking
2872:
2865:
2786:Simon Donaldson
2772:
2766:
2736:
2735:
2725:
2723:
2714:
2713:
2709:
2699:
2697:
2688:
2687:
2683:
2673:
2671:
2658:
2657:
2653:
2643:
2641:
2629:
2628:
2624:
2614:
2612:
2599:
2598:
2594:
2584:
2582:
2569:
2568:
2564:
2554:
2552:
2543:
2542:
2538:
2528:
2526:
2513:
2512:
2508:
2498:
2496:
2483:
2482:
2478:
2468:
2466:
2453:
2452:
2448:
2438:
2436:
2423:
2422:
2418:
2408:
2406:
2393:
2392:
2388:
2378:
2376:
2363:
2362:
2358:
2348:
2346:
2330:
2329:
2325:
2315:
2313:
2300:
2299:
2295:
2285:
2283:
2274:
2273:
2269:
2259:
2257:
2241:
2240:
2236:
2226:
2224:
2211:
2210:
2206:
2196:
2194:
2181:
2180:
2176:
2122:
2121:
2117:
2065:
2064:
2060:
2008:
2007:
2003:
1978:10.1038/nrc2876
1957:
1956:
1952:
1942:
1940:
1883:
1882:
1878:
1868:
1866:
1834:(6765): 41–45.
1821:
1820:
1816:
1806:
1804:
1757:
1756:
1752:
1703:
1702:
1698:
1662:
1661:
1657:
1619:
1618:
1614:
1577:
1576:
1572:
1562:
1560:
1523:
1522:
1518:
1508:
1506:
1502:
1469:
1466:
1459:
1458:
1454:
1418:
1417:
1413:
1359:
1358:
1354:
1306:
1305:
1301:
1263:
1262:
1258:
1248:
1246:
1242:
1231:
1227:
1226:
1222:
1212:
1210:
1206:
1171:Current Biology
1165:
1160:
1159:
1155:
1145:
1143:
1127:
1126:
1122:
1112:
1110:
1097:
1096:
1089:
1079:
1077:
1063:
1062:
1058:
1002:
1001:
990:
980:
978:
965:
964:
960:
950:
948:
935:
934:
923:
913:
911:
895:
894:
885:
875:
873:
858:
857:
850:
840:
838:
825:
824:
820:
815:
674:
651:Thomas Jenuwein
591:
576:transcription.
473:
472:
471:
456:
452:
447:
343:
280:
215:
191:
187:
183:
152:
148:
144:
140:
136:
132:
98:
82:
73:
69:
68:January 8, 2023
60:
51:
45:
43:
26:
17:
12:
11:
5:
4257:
4255:
4247:
4246:
4241:
4236:
4231:
4226:
4221:
4216:
4211:
4206:
4201:
4196:
4191:
4186:
4181:
4176:
4171:
4161:
4160:
4154:
4153:
4151:
4150:
4136:
4122:
4111:Katalin KarikĂł
4108:
4094:
4083:
4081:
4077:
4076:
4074:
4073:
4066:Yoshio Okamoto
4063:
4060:Jacques Miller
4049:
4035:
4025:
4011:
4008:C. David Allis
4001:
3991:
3984:Nicholas Lydon
3973:
3962:Dennis Ritchie
3955:
3952:Peter Vitousek
3944:
3942:
3938:
3937:
3935:
3934:
3927:Dennis Meadows
3924:
3917:Robert E. Kahn
3910:
3903:Peter GrĂĽnberg
3896:
3886:
3872:
3869:John H. Lawton
3858:
3851:James A. Yorke
3844:
3830:
3820:
3809:
3807:
3803:
3802:
3800:
3799:
3785:
3771:
3753:
3746:Charles K. Kao
3743:
3733:
3730:Arvid Carlsson
3723:
3720:Kary B. Mullis
3713:
3703:
3693:
3674:
3672:
3668:
3667:
3665:
3664:
3654:
3647:Luc Montagnier
3628:
3617:Henry Beachell
3614:
3607:David Turnbull
3604:
3597:John R. Pierce
3593:
3591:
3587:
3586:
3580:
3578:
3577:
3570:
3563:
3555:
3546:
3545:
3543:
3542:
3523:Paul Negulescu
3508:
3493:Demis Hassabis
3482:
3463:Katalin KarikĂł
3456:
3431:
3409:
3402:Xiaowei Zhuang
3387:
3376:Kazutoshi Mori
3365:
3343:
3321:
3295:
3269:
3242:Titia de Lange
3230:David Botstein
3222:
3220:
3214:
3213:
3211:
3210:
3200:
3182:
3172:
3162:
3148:
3142:
3131:Sergio Ferrara
3124:
3114:
3104:
3097:Lyman Page Jr.
3093:Norman Jarosik
3082:
3068:
3057:Takaaki Kajita
3014:
3013:project (2016)
2992:
2970:
2960:
2954:
2916:
2905:Nathan Seiberg
2901:Juan Maldacena
2877:
2875:
2867:
2866:
2864:
2863:
2857:
2851:
2845:
2839:
2833:
2827:
2824:James McKernan
2817:
2811:
2805:
2802:Richard Taylor
2782:
2780:
2774:
2773:
2767:
2765:
2764:
2757:
2750:
2742:
2734:
2733:
2707:
2681:
2651:
2622:
2592:
2575:March of Dimes
2562:
2536:
2506:
2476:
2446:
2425:"Past Winners"
2416:
2386:
2356:
2323:
2293:
2267:
2234:
2204:
2174:
2115:
2058:
2001:
1972:(7): 457–469.
1950:
1908:10.1.1.453.900
1876:
1814:
1750:
1696:
1669:Molecular Cell
1655:
1634:(6): 905–915.
1627:Molecular Cell
1612:
1591:(3): 279–291.
1570:
1536:(6): 348–360.
1516:
1464:
1452:
1411:
1372:(5): 786–794.
1352:
1299:
1278:(6): 843–851.
1256:
1220:
1153:
1120:
1087:
1056:
988:
958:
921:
883:
848:
817:
816:
814:
811:
796:Phi Beta Kappa
792:
791:
785:
780:Member of the
778:
772:
766:
760:
754:
748:
742:
736:
726:
720:
710:
700:
694:
688:
682:
677:Member of the
673:
670:
632:ubiquitylation
589:
457:
450:
449:
448:
446:
443:
379:full professor
342:
339:
329:in 1975 and a
311:basic research
279:
276:
235:
234:
231:
230:
225:
219:
218:
202:
196:
195:
178:
174:
173:
168:
164:
163:
157:
156:
127:
123:
122:
116:
115:Known for
112:
111:
88:
84:
83:
74:
72:(aged 71)
66:
62:
61:
52:
50:March 22, 1951
41:
37:
36:
28:
27:
24:
15:
13:
10:
9:
6:
4:
3:
2:
4256:
4245:
4242:
4240:
4237:
4235:
4232:
4230:
4227:
4225:
4222:
4220:
4217:
4215:
4212:
4210:
4207:
4205:
4202:
4200:
4197:
4195:
4192:
4190:
4187:
4185:
4182:
4180:
4177:
4175:
4172:
4170:
4167:
4166:
4164:
4148:
4144:
4140:
4139:Brian Hoskins
4137:
4134:
4130:
4126:
4123:
4120:
4116:
4115:Drew Weissman
4112:
4109:
4106:
4102:
4098:
4095:
4092:
4088:
4085:
4084:
4082:
4078:
4071:
4067:
4064:
4061:
4057:
4053:
4052:Akira Yoshino
4050:
4047:
4043:
4039:
4036:
4033:
4029:
4026:
4023:
4022:Alain Fischer
4019:
4015:
4012:
4009:
4005:
4002:
3999:
3995:
3992:
3989:
3988:Masato Sagawa
3985:
3981:
3977:
3974:
3971:
3970:Toshio Hirano
3967:
3963:
3959:
3956:
3953:
3949:
3946:
3945:
3943:
3939:
3932:
3931:David E. Kuhl
3928:
3925:
3922:
3918:
3914:
3911:
3908:
3904:
3900:
3897:
3894:
3890:
3889:John Houghton
3887:
3884:
3880:
3876:
3873:
3870:
3866:
3862:
3861:Kenichi Honda
3859:
3856:
3852:
3848:
3845:
3842:
3838:
3834:
3831:
3828:
3824:
3821:
3818:
3814:
3811:
3810:
3808:
3804:
3797:
3793:
3789:
3786:
3783:
3779:
3775:
3772:
3769:
3765:
3761:
3757:
3754:
3751:
3747:
3744:
3741:
3737:
3736:Nick Holonyak
3734:
3731:
3727:
3724:
3721:
3717:
3714:
3711:
3707:
3704:
3701:
3697:
3694:
3691:
3687:
3683:
3679:
3678:Marvin Minsky
3676:
3675:
3673:
3669:
3662:
3658:
3655:
3652:
3648:
3644:
3640:
3636:
3632:
3629:
3626:
3622:
3618:
3615:
3612:
3608:
3605:
3602:
3598:
3595:
3594:
3592:
3588:
3583:
3576:
3571:
3569:
3564:
3562:
3557:
3556:
3553:
3540:
3536:
3532:
3531:Thomas Gasser
3528:
3524:
3520:
3519:Sabine Hadida
3516:
3512:
3509:
3506:
3502:
3498:
3494:
3490:
3486:
3483:
3480:
3476:
3472:
3468:
3467:Drew Weissman
3464:
3460:
3457:
3452:
3447:
3443:
3439:
3435:
3432:
3429:
3425:
3421:
3417:
3413:
3410:
3407:
3403:
3399:
3398:Angelika Amon
3395:
3391:
3388:
3385:
3381:
3377:
3373:
3369:
3366:
3363:
3359:
3355:
3354:Roeland Nusse
3351:
3347:
3344:
3341:
3337:
3333:
3329:
3325:
3324:Edward Boyden
3322:
3319:
3315:
3311:
3307:
3306:Victor Ambros
3303:
3299:
3296:
3293:
3289:
3285:
3281:
3277:
3276:Mahlon DeLong
3273:
3270:
3267:
3263:
3259:
3255:
3251:
3247:
3243:
3239:
3235:
3231:
3227:
3224:
3223:
3221:
3219:
3218:Life sciences
3215:
3208:
3204:
3201:
3198:
3197:Peter W. Shor
3194:
3193:David Deutsch
3190:
3186:
3183:
3180:
3176:
3173:
3170:
3166:
3163:
3160:
3159:Blayne Heckel
3156:
3152:
3149:
3146:
3143:
3140:
3136:
3132:
3128:
3125:
3122:
3118:
3115:
3112:
3108:
3105:
3102:
3101:David Spergel
3098:
3094:
3090:
3086:
3083:
3080:
3076:
3072:
3069:
3066:
3062:
3058:
3054:
3050:
3046:
3042:
3038:
3034:
3030:
3029:Atsuto Suzuki
3026:
3025:Daya Bay team
3022:
3018:
3015:
3012:
3008:
3004:
3000:
2999:Ronald Drever
2996:
2993:
2990:
2986:
2982:
2981:Brian Schmidt
2978:
2974:
2971:
2968:
2964:
2963:Michael Green
2961:
2958:
2955:
2952:
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2944:
2943:Guido Tonelli
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2913:Edward Witten
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2860:Simon Brendle
2858:
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2842:Martin Hairer
2840:
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2814:Jean Bourgain
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2217:Dickson Prize
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1848:10.1038/47412
1845:
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644:
643:transcription
640:
635:
633:
629:
625:
622:, identified
621:
617:
613:
609:
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601:
597:
593:
586:
583:(part of the
582:
577:
575:
571:
568:
567:transcription
565:
561:
557:
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101:
96:
92:
89:
85:
81:
77:
67:
63:
59:
55:
42:
38:
34:
29:
22:
19:
4091:Svante Pääbo
4028:Hideo Hosono
4007:
3998:Jean Fréchet
3980:Brian Druker
3976:Janet Rowley
3958:Ken Thompson
3875:Makoto Nagao
3837:Anne McLaren
3778:Jozef Schell
3706:Gerhard Ertl
3700:John J. Wild
3686:Dan McKenzie
3651:Robert Gallo
3643:Frank Fenner
3621:Gurdev Khush
3479:Pascal Mayer
3424:David Julius
3406:Zhijian Chen
3372:Peter Walter
3368:Joanne Chory
3340:Svante Pääbo
3301:
3238:Hans Clevers
3164:
3126:
3117:Charles Kane
3106:
3089:Gary Hinshaw
3007:Rainer Weiss
2994:
2953:(LHC) (2013)
2918:
2897:Andrei Linde
2726:February 16,
2724:. Retrieved
2720:the original
2710:
2700:February 16,
2698:. Retrieved
2694:the original
2684:
2672:. Retrieved
2668:the original
2654:
2642:. Retrieved
2638:the original
2625:
2613:. Retrieved
2609:the original
2595:
2583:. Retrieved
2579:the original
2565:
2553:. Retrieved
2549:the original
2539:
2527:. Retrieved
2523:the original
2509:
2497:. Retrieved
2493:the original
2479:
2467:. Retrieved
2463:the original
2449:
2437:. Retrieved
2433:the original
2419:
2407:. Retrieved
2403:the original
2389:
2377:. Retrieved
2373:the original
2359:
2347:. Retrieved
2343:the original
2326:
2314:. Retrieved
2310:the original
2296:
2284:. Retrieved
2280:the original
2270:
2258:. Retrieved
2254:the original
2237:
2225:. Retrieved
2221:the original
2207:
2195:. Retrieved
2191:the original
2177:
2134:
2128:
2118:
2075:
2071:
2061:
2018:
2014:
2004:
1969:
1963:
1953:
1943:February 20,
1941:. Retrieved
1937:the original
1898:
1892:
1879:
1869:February 19,
1867:. Retrieved
1831:
1827:
1817:
1807:February 18,
1805:. Retrieved
1769:
1763:
1753:
1716:
1710:
1699:
1672:
1668:
1658:
1631:
1625:
1615:
1588:
1584:
1573:
1563:February 17,
1561:. Retrieved
1533:
1529:
1519:
1509:February 16,
1507:. Retrieved
1500:the original
1477:
1473:
1455:
1431:(1): 18–21.
1428:
1424:
1414:
1369:
1365:
1355:
1318:
1312:
1302:
1275:
1269:
1259:
1249:February 15,
1247:. Retrieved
1240:the original
1223:
1213:February 14,
1211:. Retrieved
1204:the original
1175:
1169:
1156:
1146:February 11,
1144:. Retrieved
1140:the original
1123:
1111:. Retrieved
1107:the original
1078:. Retrieved
1074:the original
1059:
1014:
1008:
979:. Retrieved
975:the original
961:
949:. Retrieved
945:the original
912:. Retrieved
908:the original
901:
874:. Retrieved
870:the original
863:
839:. Retrieved
835:the original
821:
804:
793:
735:Award (2008)
691:Massry Prize
663:
639:histone code
636:
578:
556:co-activator
539:
533:
525:micronucleus
513:macronucleus
509:dual nucleus
500:
484:
474:
463:
432:
426:Biology and
420:Jack Fishman
394:
377:in 1986 and
371:Cell Biology
367:Biochemistry
344:
292:city planner
281:
258:Biology and
248:Jack Fishman
239:
238:
211:
204:
177:Institutions
160:
118:Research of
70:(2023-01-08)
18:
4174:2023 deaths
4169:1951 births
3899:Albert Fert
3855:Seiji Ogawa
3716:Frank Press
3582:Japan Prize
3497:John Jumper
3449: [
3434:David Baker
3380:Kim Nasmyth
3362:Huda Zoghbi
3336:Helen Hobbs
3310:Gary Ruvkun
3250:Eric Lander
3121:Eugene Mele
3079:Cumrun Vafa
3067:team (2016)
3021:Kam-Biu Luk
3017:Yifang Wang
2927:Peter Jenni
2871:Fundamental
2798:Terence Tao
2794:Jacob Lurie
2778:Mathematics
2674:October 14,
2644:February 8,
2615:February 8,
2585:February 8,
2555:February 1,
2529:January 16,
2499:February 7,
2469:February 6,
2459:Japan Prize
2439:February 6,
2409:February 6,
2379:February 6,
2349:February 6,
2316:February 5,
2286:February 5,
2260:December 5,
2227:February 3,
2197:February 3,
1236:Japan Prize
1113:October 16,
1080:October 19,
981:February 7,
951:January 30,
914:January 23,
876:January 30,
841:February 1,
745:Japan Prize
655:epigenetics
540:Tetrahymena
519:active and
507:due to its
501:Tetrahymena
494:unicellular
486:Tetrahymena
428:Epigenetics
260:Epigenetics
171:Epigenetics
134:Japan Prize
4163:Categories
4070:Rattan Lal
4046:Adi Shamir
3893:Akira Endo
3813:Ian McHarg
3760:Bruce Ames
3639:Isao Arita
3584:recipients
3332:John Hardy
3203:John Cardy
3003:Kip Thorne
2985:Adam Riess
2949:(CMS) and
2909:Ashoke Sen
2836:Alex Eskin
1530:Chromosoma
813:References
624:SET domain
620:histone H3
594:needed to
570:activation
552:homologous
466:(Q1064064)
439:Washington
284:Cincinnati
80:Washington
54:Cincinnati
46:1951-03-22
3913:Vint Cerf
3774:Leo Esaki
3750:Masao Ito
3511:Carl June
3442:Dennis Lo
2951:Lyn Evans
2933:(ATLAS),
2885:Alan Guth
2771:laureates
2169:256901502
2053:256577181
1903:CiteSeerX
666:mutations
574:regulates
538:p55 from
497:eukaryote
481:chromatin
424:Chromatin
392:in 1990.
256:Chromatin
87:Education
3063:and the
3051:and the
3039:and the
3031:and the
3023:and the
2808:Ian Agol
2161:36795814
2110:30894748
2045:36737544
1996:20574448
1925:11498575
1856:10638745
1794:12077605
1745:11839797
1691:14690610
1650:10911985
1607:10975519
1558:29723188
1463:"The TAF
1447:30217363
1406:14172992
1347:25944906
1192:19515351
1051:16618930
596:initiate
548:histones
529:germline
515:that is
491:ciliated
445:Research
3165:Special
3127:Special
3107:Special
3033:KamLAND
2995:Special
2919:Special
2873:physics
2139:Bibcode
2130:Science
2101:6512987
2080:Bibcode
2023:Bibcode
1987:3262678
1933:1883924
1894:Science
1864:4418993
1836:Bibcode
1802:4338471
1774:Bibcode
1550:9362543
1496:8980232
1374:Bibcode
1338:4481195
1294:8601308
1200:9841779
1042:1458902
1019:Bibcode
705:of the
659:cancers
612:mitogen
608:mitosis
521:somatic
459:Scholia
435:Seattle
407:at the
383:Biology
349:in the
313:in his
307:biology
299:teacher
76:Seattle
4149:(2024)
4135:(2023)
4121:(2022)
4107:(2021)
4093:(2020)
4072:(2019)
4062:(2018)
4048:(2017)
4034:(2016)
4024:(2015)
4010:(2014)
3990:(2012)
3972:(2011)
3954:(2010)
3933:(2009)
3923:(2008)
3909:(2007)
3895:(2006)
3885:(2005)
3871:(2004)
3857:(2003)
3843:(2002)
3829:(2001)
3819:(2000)
3798:(1999)
3784:(1998)
3770:(1997)
3752:(1996)
3742:(1995)
3738:Jr. /
3732:(1994)
3722:(1993)
3712:(1992)
3702:(1991)
3692:(1990)
3663:(1989)
3653:(1988)
3627:(1987)
3613:(1986)
3603:(1985)
3541:(2024)
3507:(2023)
3481:(2022)
3455:(2021)
3430:(2020)
3408:(2019)
3386:(2018)
3364:(2017)
3342:(2016)
3320:(2015)
3294:(2014)
3268:(2013)
3209:(2024)
3199:(2023)
3181:(2022)
3179:Jun Ye
3171:(2021)
3161:(2021)
3147:(2020)
3141:(2019)
3123:(2019)
3113:(2018)
3103:(2018)
3081:(2017)
3055:team,
3047:team,
3035:team,
2991:(2015)
2969:(2014)
2959:(2013)
2915:(2012)
2862:(2024)
2856:(2023)
2850:(2022)
2844:(2021)
2838:(2020)
2832:(2019)
2826:(2018)
2816:(2017)
2810:(2016)
2804:(2015)
2167:
2159:
2108:
2098:
2072:Nature
2051:
2043:
2015:Nature
1994:
1984:
1931:
1923:
1905:
1862:
1854:
1828:Nature
1800:
1792:
1765:Nature
1743:
1736:134702
1733:
1689:
1648:
1605:
1556:
1548:
1494:
1445:
1404:
1397:300163
1394:
1345:
1335:
1292:
1198:
1190:
1049:
1039:
790:(2022)
784:(2019)
777:(2018)
771:(2017)
765:(2016)
759:(2015)
753:(2014)
747:(2014)
741:(2010)
725:(2007)
719:(2007)
709:(2005)
703:Member
699:(2004)
693:(2003)
687:(2002)
681:(2001)
616:lysine
544:enzyme
361:as an
341:Career
315:senior
216:(1978)
214:
200:Thesis
167:Fields
126:Awards
4080:2020s
3941:2010s
3806:2000s
3671:1990s
3590:1980s
3453:]
2165:S2CID
2049:S2CID
1929:S2CID
1860:S2CID
1798:S2CID
1554:S2CID
1503:(PDF)
1470:(PDF)
1243:(PDF)
1232:(PDF)
1207:(PDF)
1196:S2CID
1166:(PDF)
733:Merck
618:9 of
560:yeast
542:, an
3537:and
3477:and
3392:and
3338:and
3316:and
3290:and
3264:and
3205:and
3177:and
3157:and
3119:and
3059:and
3011:LIGO
2965:and
2800:and
2728:2023
2702:2023
2676:2022
2646:2023
2617:2022
2587:2022
2557:2022
2531:2023
2501:2023
2471:2023
2441:2023
2411:2023
2381:2023
2351:2023
2318:2023
2288:2023
2262:2022
2229:2023
2199:2023
2157:PMID
2106:PMID
2041:PMID
1992:PMID
1945:2023
1921:PMID
1871:2023
1852:PMID
1809:2023
1790:PMID
1741:PMID
1687:PMID
1646:PMID
1603:PMID
1585:Cell
1565:2023
1546:PMID
1511:2023
1492:PMID
1474:Cell
1443:PMID
1425:Cell
1402:PMID
1343:PMID
1290:PMID
1271:Cell
1251:2023
1215:2023
1188:PMID
1148:2023
1115:2019
1082:2021
1047:PMID
983:2023
953:2023
916:2023
878:2023
843:2023
610:and
602:and
581:TAF1
489:, a
288:Ohio
270:and
65:Died
58:Ohio
40:Born
3045:T2K
3041:K2K
2147:doi
2135:379
2096:PMC
2088:doi
2076:567
2031:doi
2019:614
1982:PMC
1974:doi
1913:doi
1899:293
1844:doi
1832:403
1782:doi
1770:418
1731:PMC
1721:doi
1677:doi
1636:doi
1593:doi
1589:102
1538:doi
1534:106
1482:doi
1433:doi
1429:175
1392:PMC
1382:doi
1333:PMC
1323:doi
1319:290
1280:doi
1180:doi
1037:PMC
1027:doi
1015:103
564:DNA
558:in
385:at
355:PhD
331:PhD
327:MSc
274:).
108:PhD
104:MSc
95:BSc
4165::
4145:/
4141:/
4131:/
4117:/
4113:/
4103:/
4099:/
4089:/
4068:/
4058:/
4054:/
4044:/
4040:/
4030:/
4020:/
4016:/
4006:/
3996:/
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