48:
655:
Howard, Nigel; Abell, Chris; Blakemore, Wendy; Chessari, Gianni; Congreve, Miles; Howard, Steven; Jhoti, Harren; Murray, Christopher W.; Seavers, Lisa C. A.; van
Montfort, Rob L. M. (2006). "Application of Fragment Screening and Fragment Linking to the Discovery of Novel Thrombin Inhibitors†".
318:
biosynthesis (1982–83). In 1984, Abell joined the department of chemistry of the
University of Cambridge, successively holding the positions of demonstrator, lecturer and reader in chemical biology, and becoming professor in biological chemistry in 2002. He held visiting professorships at the
1328:
734:; Osborne, Andrew P.; Stephens, Elaine; Davies, Gareth M.; Coggins, John R.; Abell, Chris (2004). "Identification of 4-Amino-4-deoxychorismate Synthase as the Molecular Target for the Antimicrobial Action of (6S)-6-Fluoroshikimate".
1154:
1973:
1968:
445:, and a Yamada Science Foundation Award. In 2008 he was the MIT Novartis Lecturer, and in 2011 was a BIC International Fellow at the University of Canterbury, Christchurch, New Zealand. He was elected a
577:
Huebner, A.; Srisa-Art, M.; Holt, D.; Abell, C.; Hollfelder, F.; deMello, A. J.; Edel, J. B. (2007). "Quantitative detection of protein expression in single cells using droplet microfluidics".
693:
Bruckbauer, Andreas; Zhou, Dejian; Kang, Dae-Joon; Korchev, Yuri E.; Abell, Chris; Klenerman, David (2004). "An
Addressable Antibody Nanoarray Produced on a Nanostructured Surface".
1601:
1433:
1226:
1983:
1978:
1988:
914:
Mahapatro, Mrinal; Gibson, Christopher; Abell, Chris; Rayment, Trevor (2003). "Chiral discrimination of basic and hydrophobic molecules by chemical force spectroscopy".
859:
Albert, Armando; Dhanaraj, Venugopal; Genschel, Ulrich; Khan, Ghalib; Ramjee, Manoj K.; Pulido, Rosaline; Sibanda, B. Lynn; Delft, Frank von; Witty, Michael;
1396:
610:
Kerbarh, Olivier; Ciulli, Alessio; Chirgadze, Dimitri Y.; Blundell, Tom L.; Abell, Chris (2007). "Nucleophile
Selectivity of Chorismate-Utilizing Enzymes".
1434:"From farm to fame, Cambridge's 'cereal' life science entrepreneur | Business Weekly | Technology News | Business news | Cambridge and the East of England"
425:
In 1981, he married
Katherine Abell, who worked with him at the department of chemistry in Cambridge; they had a son. He died suddenly on 26 October 2020.
1876:
446:
37:
867:; Abell, Chris (1998). "Crystal structure of aspartate decarboxylase at 2.2 Å resolution provides evidence for an ester in protein self–processing".
33:
1327:
Theberge, Ashleigh B.; Courtois, Fabienne; Schaerli, Yolanda; Fischlechner, Martin; Abell, Chris; Hollfelder, Florian; Huck, Wilhelm T. S. (2010).
2008:
1963:
1993:
1508:
1263:
328:
263:
812:; Ostanin, Victor P.; Abell, Chris; Klenerman, David (2001). "Direct and sensitive detection of a human virus by rupture event scanning".
1295:
1584:
409:, which uses fragment-based drug discovery technology to discover cancer therapeutics. In 2001, he co-founded Akubio, which developed
2003:
1203:
283:
1112:
1246:
775:; Abell, Chris (2003). "Rapid screening by MALDI-TOF mass spectrometry to probe binding specificity at enzyme active sites".
320:
1311:
348:
267:
515:
Blundell, Tom L.; Jhoti, Harren; Abell, Chris (2002). "High-throughput crystallography for lead discovery in drug design".
417:
to develop microdroplet technology. In 2012 he co-founded Aqdot, a company developing a new microencapsulation technology.
47:
1937:
517:
378:
127:
1415:
1481:
434:
287:
1035:
1593:
450:
29:
1810:
413:
for detecting bacteria and viruses; it was acquired by
Inverness Medical Innovations in 2008. In 2010, he co-founded
1795:
1745:
442:
1917:
1695:
1527:
1007:
869:
1860:
1725:
340:
332:
311:
1785:
1730:
1635:
1089:
394:
215:
173:
100:
1577:
526:
1775:
1670:
351:, from 1986; and was the college's Todd-Hamied Fellow. In 2013 he was appointed the first director of
1998:
1958:
1735:
814:
163:
531:
355:
affairs at the
University of Cambridge, and in 2016 was appointed pro-vice-chancellor for research.
1660:
970:
1815:
1367:
902:
847:
643:
560:
438:
145:
1922:
1505:
1271:
1562:
1329:"Microdroplets in Microfluidics: An Evolving Platform for Discoveries in Chemistry and Biology"
1845:
1805:
1770:
1665:
1650:
1570:
1359:
1351:
1220:
1164:
980:
939:
931:
894:
886:
864:
839:
831:
796:
788:
772:
759:
751:
718:
710:
681:
673:
635:
627:
598:
590:
552:
544:
503:
485:
382:
131:
1830:
1825:
1720:
1705:
1690:
1685:
1655:
1343:
1292:
1176:
1021:
992:
923:
878:
823:
780:
743:
702:
665:
619:
582:
536:
493:
477:
307:
259:
202:
190:
177:
1544:
1907:
1835:
1790:
1755:
1645:
1531:
1512:
1419:
1299:
1250:
1130:
572:
From
Microdroplets to Microfluidics: Selective Emulsion Separation in Microfluidic Devices
414:
1855:
1850:
1820:
1780:
1710:
1640:
1620:
498:
465:
390:
219:
135:
927:
1952:
1932:
1912:
1902:
1750:
1740:
1630:
1625:
1597:
374:
303:
271:
123:
1371:
647:
1840:
1715:
1116:
1036:"Christopher ABELL - Personal Appointments (free information from Companies House)"
906:
860:
851:
731:
564:
366:
352:
336:
115:
1397:
Vargas L. Recycled
Cambridge biosensor technology attracts millions in investment
1243:
481:
274:, Abell's research was described as having "changed the face of drug discovery."
1927:
1892:
1760:
1700:
1675:
809:
370:
119:
1800:
1680:
1458:
1412:
386:
363:
291:
1355:
935:
890:
835:
792:
755:
714:
677:
631:
594:
548:
489:
1897:
1168:
984:
410:
1363:
1347:
943:
843:
800:
763:
722:
685:
639:
623:
602:
556:
507:
1293:
Christ's
College, University of Cambridge: The Fellows of Christ's College
898:
344:
324:
1384:
882:
827:
1765:
1385:
University of Cambridge: Department of Chemistry: Professor Chris Abell
359:
315:
1524:
1312:
University of Cambridge: new senior post to support post-doc community
747:
706:
669:
405:
Abell was the co-founder of several companies. In 1999, he co-founded
234:
784:
586:
184:
1515:, University of Canterbury – Christchurch. Retrieved 3 December 2013
1205:
Abell Group Home Page: Curriculum vitae: Professor Christopher Abell
1094:, Department of Chemistry, University of Cambridge, 27 October 2020
540:
1172:
1017:
988:
406:
111:
1244:
Astex Therapeutics: Scientific Advisors and Clinical Consultants
358:
Abell published over 200 papers. His research interests include
294:
biosynthesis for research supervised by James Staunton in 1982.
1566:
1525:
The Academy of Medical Sciences: Fellows: Newly elected fellows
1974:
Members of the University of Cambridge Department of Chemistry
1969:
Fellows of the Academy of Medical Sciences (United Kingdom)
1132:
50 leading scientists elected as Fellows of Royal Society
972:
Studies on the reaction mechanism of chorismate synthase
302:
Abell held a research fellowship in the laboratory of
1885:
1869:
1608:
262:who was a professor of biological chemistry at the
258:(11 November 1957 – 26 October 2020) was a British
229:
211:
201:
183:
169:
159:
141:
107:
96:
88:
76:
57:
23:
1463:, Department of Chemistry, University of Cambridge
1009:Biophysical studies of protein-ligand interactions
1208:, archived from the original on 25 September 2006
1225:: CS1 maint: bot: original URL status unknown (
1091:Professor Chris Abell FRS, FMedSci (1957 - 2020)
466:"Fragment-based approaches to enzyme inhibition"
1084:
1082:
1080:
437:(ICI) Prize in Organic Chemistry in 1992, the
1578:
389:; reactions in microdroplets; and biological
8:
964:
962:
730:Bulloch, Esther M. M.; Jones, Michelle A.;
1585:
1571:
1563:
1063:
1061:
1059:
1057:
1055:
1053:
1051:
1049:
46:
20:
1989:Fellows of the Royal Society of Chemistry
1482:"RSC Hickinbottom Award Previous Winners"
530:
497:
447:Fellow of the Academy of Medical Sciences
1239:
1237:
736:Journal of the American Chemical Society
695:Journal of the American Chemical Society
290:in 1979 followed by PhD on the topic of
286:, gaining an Bachelor of Arts degree in
1545:"Professor Christopher Abell Biography"
1336:Angewandte Chemie International Edition
1322:
1320:
1163:(PhD thesis). University of Cambridge.
1016:(PhD thesis). University of Cambridge.
979:(PhD thesis). University of Cambridge.
958:
808:Cooper, Matthew A.; Dultsev, Fedor N.;
393:. His former doctoral students include
1984:Alumni of St John's College, Cambridge
1979:Fellows of Christ's College, Cambridge
1218:
464:Ciulli, Alessio; Abell, Chris (2007).
16:British biological chemist (1957–2020)
7:
1198:
1196:
1194:
1192:
1190:
1188:
1186:
771:Webb, Michael E.; Stephens, Elaine;
329:University of Santiago de Compostela
264:Yusuf Hamied Department of Chemistry
14:
969:Balasubramanian, Shankar (1991).
1264:"Christ's College Magazine 2019"
470:Current Opinion in Biotechnology
1460:The Abell Group: Group Members
1115:. 7 April 2013. Archived from
1069:Debrett's People of Today 2012
658:Journal of Medicinal Chemistry
321:Australian National University
270:. On his 2016 election to the
1:
2009:21st-century British chemists
1964:20th-century British chemists
928:10.1016/S0304-3991(03)00055-X
518:Nature Reviews Drug Discovery
1994:Fellows of the Royal Society
1067:Abell, Prof Christopher. In
482:10.1016/j.copbio.2007.09.003
435:Imperial Chemical Industries
284:St John's College, Cambridge
1314:(accessed 28 November 2013)
1153:Abell, Christopher (1982).
1113:"Scientific Advisory Board"
1071:(accessed 15 January 2012)
451:Fellow of the Royal Society
349:Christ's College, Cambridge
268:Christ's College, Cambridge
2025:
1796:Lakshminarayanan Mahadevan
1413:Sphere Fluidics: 2010 News
1231:(accessed 15 January 2013)
1040:beta.companieshouse.gov.uk
443:Royal Society of Chemistry
266:and Todd-Hamied Fellow of
1534:(accessed 7 January 2013)
1530:27 September 2013 at the
1422:(accessed 7 January 2013)
1403:(accessed 5 January 2009)
1387:(accessed 5 January 2009)
1302:(accessed 7 January 2013)
1253:(accessed 5 January 2009)
870:Nature Structural Biology
379:fragment-based approaches
225:
152:
128:fragment-based approaches
45:
2004:Brown University fellows
1438:www.businessweekly.co.uk
1418:18 November 2012 at the
1006:Ciulli, Alessio (2006).
449:(FMedSci) in 2012 and a
341:Paul Sabatier University
333:University of Canterbury
1156:Polyketide biosynthesis
1073:(subscription required)
777:Chemical Communications
579:Chemical Communications
433:His awards include the
395:Shankar Balasubramanian
216:Shankar Balasubramanian
191:Polyketide biosynthesis
174:University of Cambridge
101:University of Cambridge
1348:10.1002/anie.200906653
1249:14 August 2011 at the
624:10.1002/cbic.200700019
385:; bacterial and plant
282:Abell was educated at
1506:International Fellows
457:Selected publications
347:. He was a fellow of
1511:4 March 2016 at the
1298:5 March 2013 at the
815:Nature Biotechnology
407:Astex Technology Ltd
164:Biological chemistry
883:10.1038/nsb0498-289
828:10.1038/nbt0901-833
401:Commercial ventures
369:as targets for the
298:Career and research
118:as targets for the
1816:Simon Peyton Jones
1177:uk.bl.ethos.350039
1022:uk.bl.ethos.613799
993:uk.bl.ethos.386780
439:Hickinbottom Award
429:Awards and honours
260:biological chemist
146:Hickinbottom Award
1946:
1945:
1771:Eugenia Kumacheva
1666:Alastair Compston
1651:Katharine Cashman
1342:(34): 5846–5868.
748:10.1021/ja048312f
742:(32): 9912–9913.
707:10.1021/ja0317426
701:(21): 6508–6509.
670:10.1021/jm050850v
383:enzyme inhibition
256:Christopher Abell
253:
252:
212:Doctoral students
154:Scientific career
134:; and biological
132:enzyme inhibition
62:Christopher Abell
2016:
1831:Sriram Ramaswamy
1776:Corinne Le Quéré
1706:Maria Fitzgerald
1691:Marcus du Sautoy
1686:Christl Donnelly
1656:Sarah Cleaveland
1587:
1580:
1573:
1564:
1557:
1556:
1554:
1552:
1541:
1535:
1522:
1516:
1503:
1497:
1496:
1494:
1492:
1478:
1472:
1471:
1470:
1468:
1455:
1449:
1448:
1446:
1444:
1429:
1423:
1410:
1404:
1401:(27 August 2008)
1394:
1388:
1382:
1376:
1375:
1333:
1324:
1315:
1309:
1303:
1290:
1284:
1283:
1281:
1279:
1270:. Archived from
1260:
1254:
1241:
1232:
1230:
1224:
1216:
1215:
1213:
1200:
1181:
1180:
1150:
1144:
1143:
1142:
1140:
1127:
1121:
1120:
1119:on 7 April 2013.
1109:
1103:
1102:
1101:
1099:
1086:
1075:
1065:
1044:
1043:
1032:
1026:
1025:
1003:
997:
996:
966:
947:
922:(1–4): 297–301.
910:
865:Smith, Alison G.
861:Blundell, Tom L.
855:
804:
785:10.1039/b308182f
773:Smith, Alison G.
767:
732:Parker, Emily J.
726:
689:
664:(4): 1346–1355.
651:
606:
587:10.1039/b618570c
568:
534:
511:
501:
314:, USA, studying
308:Brown University
288:Natural Sciences
249:
246:
244:
242:
240:
238:
236:
203:Doctoral advisor
197:
178:Brown University
83:
72:11 November 1957
71:
69:
50:
40:
21:
2024:
2023:
2019:
2018:
2017:
2015:
2014:
2013:
1949:
1948:
1947:
1942:
1908:Jennifer Doudna
1881:
1865:
1836:Caroline Series
1791:Eleanor Maguire
1756:Ramanujan Hegde
1604:
1591:
1561:
1560:
1550:
1548:
1547:. Royal Society
1543:
1542:
1538:
1532:Wayback Machine
1523:
1519:
1513:Wayback Machine
1504:
1500:
1490:
1488:
1480:
1479:
1475:
1466:
1464:
1457:
1456:
1452:
1442:
1440:
1432:Quested, Tony.
1431:
1430:
1426:
1420:Wayback Machine
1411:
1407:
1399:Business Weekly
1395:
1391:
1383:
1379:
1331:
1326:
1325:
1318:
1310:
1306:
1300:Wayback Machine
1291:
1287:
1277:
1275:
1262:
1261:
1257:
1251:Wayback Machine
1242:
1235:
1217:
1211:
1209:
1202:
1201:
1184:
1152:
1151:
1147:
1138:
1136:
1135:, 29 April 2016
1129:
1128:
1124:
1111:
1110:
1106:
1097:
1095:
1088:
1087:
1078:
1066:
1047:
1034:
1033:
1029:
1005:
1004:
1000:
968:
967:
960:
955:
950:
916:Ultramicroscopy
913:
858:
807:
770:
729:
692:
654:
609:
581:(12): 1218–20.
576:
532:10.1.1.538.3976
514:
463:
459:
453:(FRS) in 2016.
431:
423:
415:Sphere Fluidics
403:
371:rational design
300:
280:
233:
218:
195:
176:
120:rational design
114:
81:
80:26 October 2020
67:
65:
64:
63:
53:
41:
28:
26:
17:
12:
11:
5:
2022:
2020:
2012:
2011:
2006:
2001:
1996:
1991:
1986:
1981:
1976:
1971:
1966:
1961:
1951:
1950:
1944:
1943:
1941:
1940:
1938:Ellen Williams
1935:
1930:
1925:
1920:
1915:
1910:
1905:
1900:
1895:
1889:
1887:
1883:
1882:
1880:
1879:
1873:
1871:
1867:
1866:
1864:
1863:
1858:
1856:Philip Withers
1853:
1848:
1843:
1838:
1833:
1828:
1823:
1821:Jonathon Pines
1818:
1813:
1808:
1806:Russell Morris
1803:
1798:
1793:
1788:
1783:
1778:
1773:
1768:
1763:
1758:
1753:
1748:
1746:Richard Harvey
1743:
1738:
1733:
1728:
1723:
1718:
1713:
1711:Antony Galione
1708:
1703:
1698:
1693:
1688:
1683:
1678:
1673:
1668:
1663:
1658:
1653:
1648:
1643:
1641:Martin Bridson
1638:
1633:
1628:
1623:
1621:Jas Pal Badyal
1618:
1612:
1610:
1606:
1605:
1592:
1590:
1589:
1582:
1575:
1567:
1559:
1558:
1536:
1517:
1498:
1473:
1450:
1424:
1405:
1389:
1377:
1316:
1304:
1285:
1274:on 18 May 2021
1255:
1233:
1182:
1145:
1122:
1104:
1076:
1045:
1027:
998:
957:
956:
954:
951:
949:
948:
911:
877:(4): 289–293.
856:
822:(9): 833–837.
805:
779:(19): 2416–7.
768:
727:
690:
652:
618:(6): 622–624.
607:
574:
569:
541:10.1038/nrd706
512:
476:(6): 489–496.
460:
458:
455:
430:
427:
422:
419:
402:
399:
391:nanotechnology
375:antimicrobials
299:
296:
279:
276:
251:
250:
231:
227:
226:
223:
222:
220:Alessio Ciulli
213:
209:
208:
207:James Staunton
205:
199:
198:
187:
181:
180:
171:
167:
166:
161:
157:
156:
150:
149:
143:
139:
138:
136:nanotechnology
124:antimicrobials
109:
108:Known for
105:
104:
98:
94:
93:
90:
86:
85:
84:(aged 62)
78:
74:
73:
61:
59:
55:
54:
51:
43:
42:
27:
24:
15:
13:
10:
9:
6:
4:
3:
2:
2021:
2010:
2007:
2005:
2002:
2000:
1997:
1995:
1992:
1990:
1987:
1985:
1982:
1980:
1977:
1975:
1972:
1970:
1967:
1965:
1962:
1960:
1957:
1956:
1954:
1939:
1936:
1934:
1933:Rino Rappuoli
1931:
1929:
1926:
1924:
1921:
1919:
1916:
1914:
1913:Gerd Faltings
1911:
1909:
1906:
1904:
1901:
1899:
1896:
1894:
1891:
1890:
1888:
1884:
1878:
1875:
1874:
1872:
1868:
1862:
1859:
1857:
1854:
1852:
1849:
1847:
1844:
1842:
1839:
1837:
1834:
1832:
1829:
1827:
1824:
1822:
1819:
1817:
1814:
1812:
1809:
1807:
1804:
1802:
1799:
1797:
1794:
1792:
1789:
1787:
1784:
1782:
1779:
1777:
1774:
1772:
1769:
1767:
1764:
1762:
1759:
1757:
1754:
1752:
1751:Adrian Hayday
1749:
1747:
1744:
1742:
1739:
1737:
1734:
1732:
1729:
1727:
1724:
1722:
1721:Harry Gilbert
1719:
1717:
1714:
1712:
1709:
1707:
1704:
1702:
1699:
1697:
1694:
1692:
1689:
1687:
1684:
1682:
1679:
1677:
1674:
1672:
1669:
1667:
1664:
1662:
1661:James Collier
1659:
1657:
1654:
1652:
1649:
1647:
1644:
1642:
1639:
1637:
1634:
1632:
1631:Polina Bayvel
1629:
1627:
1626:Steven Balbus
1624:
1622:
1619:
1617:
1614:
1613:
1611:
1607:
1603:
1599:
1598:Royal Society
1595:
1588:
1583:
1581:
1576:
1574:
1569:
1568:
1565:
1546:
1540:
1537:
1533:
1529:
1526:
1521:
1518:
1514:
1510:
1507:
1502:
1499:
1487:
1483:
1477:
1474:
1462:
1461:
1454:
1451:
1439:
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367:biosynthesis
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170:Institutions
153:
116:biosynthesis
82:(2020-10-26)
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1959:1957 births
1928:Pasko Rakic
1893:Robert Cava
1851:David Wales
1826:Jim Prosser
1786:David Lodge
1781:Mark Lemmon
1761:David Hight
1731:Anne Glover
1701:Artur Ekert
1676:Jack Cuzick
1636:Graham Bell
1616:Chris Abell
1486:www.rsc.org
1467:15 November
1139:2 September
1098:15 November
612:ChemBioChem
89:Nationality
25:Chris Abell
1953:Categories
1918:John Hayes
1903:Mark Davis
1801:Gil McVean
1741:Ian Graham
1696:Jim Dunlop
1681:Bill David
1212:15 January
953:References
411:biosensors
364:amino acid
339:, and the
312:Providence
292:polyketide
68:1957-11-11
1898:Vint Cerf
1671:Brian Cox
1491:1 January
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1600:elected
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