1019:
Hyde, S. C.; Emsley, P.; Hartshorn, M. J.; Mimmack, M. M.; Gileadi, U.; Pearce, S. R.; Gallagher, M. P.; Gill, D. R.; Hubbard, R. E.; Higgins, C. F. (1990). "Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport".
1122:
Higgins, C. F.; Hiles, I. D.; Salmond, G. P. C.; Gill, D. R.; Downie, J. A.; Evans, I. J.; Holland, I. B.; Gray, L.; Buckel, S. D.; Bell, A. W.; Hermodson, M. A. (1986). "A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria".
865:
Hyde, S. C.; Gill, D. R.; Higgins, C. F.; Trezise, A. E. O.; MacVinish, L. J.; Cuthbert, A. W.; Ratcliff, R.; Evans, M. J.; Colledge, W. H. (1993). "Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy".
1594:
Hulton, C. S.; Seirafi, A.; Hinton, J. C.; Sidebotham, J. M.; Waddell, L.; Pavitt, G. D.; Owen-Hughes, T.; Spassky, A.; Buc, H.; Higgins, C. F. (1990). "Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria".
1506:
Owen-Hughes, T. A.; Pavitt, G. D.; Santos, D. S.; Sidebotham, J. M.; Hulton, C. S.; Hinton, J. C.; Higgins, C. F. (1992). "The chromatin-associated protein H-NS interacts with curved DNA to influence DNA topology and gene expression".
1638:
Higgins, C. F.; Dorman, C. J.; Stirling, D. A.; Waddell, L.; Booth, I. R.; May, G.; Bremer, E. (1988). "A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. Typhimurium and E. Coli".
1276:
Higgins, C. F.; Haag, P. D.; Nikaido, K.; Ardeshir, F.; Garcia, G.; Ames, G. F. (1982). "Complete nucleotide sequence and identification of membrane components of the histidine transport operon of S. Typhimurium".
1908:
1550:
Gill, D. R.; Hyde, S. C.; Higgins, C. F.; Valverde, M. A.; Mintenig, G. M.; Sepúlveda, F. V. (1992). "Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein".
705:
Van Veen, H. W.; Callaghan, R.; Soceneantu, L.; Sardini, A.; Konings, W. N.; Higgins, C. F. (1998). "A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene".
1923:
1371:
Tame, J. R.; Murshudov, G. N.; Dodson, E. J.; Neil, T. K.; Dodson, G. G.; Higgins, C. F.; Wilkinson, A. J. (1994). "The structural basis of sequence-independent peptide binding by OppA protein".
917:
Valverde, M. A.; Díaz, M.; Sepúlveda, F. V.; Gill, D. R.; Hyde, S. C.; Higgins, C. F. (1992). "Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein".
1918:
228:
from 2007 to 2014. He took early retirement on 30 September 2014, following a discussion at Senate on limiting the powers of the Vice
Chancellor. He was previously the director of the
374:
336:
and became the
University's 23rd Vice-Chancellor. He took early retirement on 30 September 2014, following a discussion at Senate on limiting the powers of the Vice Chancellor.
1913:
1768:
Stern, M. J.; Ames, G. F.; Smith, N. H.; Robinson, E. C.; Higgins, C. F. (1984). "Repetitive extragenic palindromic sequences: A major component of the bacterial genome".
1725:
Newbury, S. F.; Smith, N. H.; Robinson, E. C.; Hiles, I. D.; Higgins, C. F. (1987). "Stabilization of translationally active mRNA by prokaryotic REP sequences".
1898:
1174:
Manson, M. D.; Blank, V.; Brade, G.; Higgins, C. F. (1986). "Peptide chemotaxis in E. Coli involves the Tap signal transducer and the dipeptide permease".
364:
1071:
Dorman, C. J.; Bhriain, N. N.; Higgins, C. F. (1990). "DNA supercoiling and environmental regulation of virulence gene expression in
Shigella flexneri".
465:
Higgins, C. F.; Payne, J. W. (1978). "Peptide transport by germinating barley embryos: Evidence for a single common carrier for di- and oligopeptides".
208:
397:
Higgins is not currently married, although he has been married twice. He has five daughters, two from his first marriage and three from the second.
1682:
Newbury, S. F.; Smith, N. H.; Higgins, C. F. (1987). "Differential mRNA stability controls relative gene expression within a polycistronic operon".
1225:
Higgins, C. F.; Ames, G. F.; Barnes, W. M.; Clement, J. M.; Hofnung, M. (1982). "A novel intercistronic regulatory element of prokaryotic operons".
200:
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382:
352:
90:
340:
563:
204:
814:
Py, B. A.; Higgins, C. F.; Krisch, H. M.; Carpousis, A. J. (1996). "A DEAD-box RNA helicase in the
Escherichia coli RNA degradosome".
1811:
592:
386:
229:
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344:
86:
543:(Who's Who 2013, A & C Black, an imprint of Bloomsbury Publishing plc, 2013; online edn, Oxford University Press)
356:
82:
378:
233:
130:
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415:"The Peptide pools of germinating barley grains: Relation to hydrolysis and transport of storage proteins"
60:
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Alongside his academic success, Professor
Higgins has also served as a scientific advisor for the
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257:
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1437:
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1250:
1199:
1148:
1096:
1045:
993:
942:
891:
839:
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679:
654:
Higgins, C. F. (2007). "Multiple molecular mechanisms for multidrug resistance transporters".
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329:
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64:
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520:
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434:
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159:
147:
1815:
1851:
325:
221:
1328:
Higgins, C. F.; Linton, K. J. (2001). "STRUCTURAL BIOLOGY: The xyz of ABC Transporters".
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851:
800:
691:
381:
Select
Committee on Science and Technology. At present Higgins is the chair of the
297:
285:
641:
1463:
Higgins, C. F. (1994). "Flip-flop: The transmembrane translocation of lipids".
217:
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1341:
232:
Clinical
Sciences Centre and Head of Division in the Faculty of Medicine at
1349:
683:
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448:
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735:
617:
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112:
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430:
486:
304:. He has published over 200 papers in leading scientific journals like
265:
177:
347:
author. Further awards have been the CIBA Medal, Fleming Prize, and a
1298:
1246:
1195:
1144:
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1041:
989:
938:
887:
835:
273:
269:
245:
141:
522:
Peptide transport by embryos of germinating barley, Hordeum vulgare
244:
Higgins was born on 24 June 1955 in
Cambridge, England. He studied
148:
Peptide transport by embryos of germinating barley, Hordeum vulgare
783:
758:
727:
968:
Higgins, C. F.; Hyde, S. C. (1991). "Channelling our thoughts".
351:
International
Scholarship along with election to Fellow of the
95:
261:
1909:
Fellows of the
Academy of Medical Sciences (United Kingdom)
16:
British geneticist and Vice-Chancellor of Durham University
564:"Durham University vice-chancellor to retire in September"
389:
and a trustee of the Kennedy Institute for Rheumatology.
1924:
Members of the European Molecular Biology Organization
296:
Higgins was appointed Nuffield Professor of Clinical
593:"Christopher Higgins: Notes from a small university"
172:
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118:
108:
78:
70:
56:
48:
30:
23:
644:Durham University; 14-04-2007; accessed 23-04-2007
1919:Vice-chancellors and wardens of Durham University
387:DKFZ (German National Cancer Centre, Heidelberg)
385:Advisory Committee, International Review Panel,
759:"E. Coli genome sequence. A blueprint for life"
220:, academic and scientific advisor. He was the
637:
635:
8:
514:
512:
1833:
20:
1914:Fellows of the Royal Society of Edinburgh
1431:
782:
534:
532:
438:
377:on Stem Cell Research and advisor to the
460:
458:
405:
353:European Molecular Biology Organization
757:Moxon, E. R.; Higgins, C. F. (1997).
413:Higgins, C. F.; Payne, J. W. (1981).
7:
1899:Alumni of the Royal College of Music
540:"HIGGINS, Prof. Christopher Francis"
341:Institute for Scientific Information
642:Durham welcomes new Vice Chancellor
339:Higgins has been recognised by the
14:
1828:Human Genetics Commission Website
562:Tallentire, Mark (5 March 2014).
212:(born 24 June 1955) is a British
525:(PhD thesis). Durham University.
324:In April 2007, he was appointed
1812:"Professor Christopher Higgins"
1416:"The ABC of channel regulation"
1894:Alumni of Grey College, Durham
1:
591:Keating, Matt (29 May 2007).
1782:10.1016/0092-8674(84)90436-7
1739:10.1016/0092-8674(87)90433-8
1696:10.1016/0092-8674(87)90599-X
1653:10.1016/0092-8674(88)90470-9
1609:10.1016/0092-8674(90)90458-Q
1565:10.1016/0092-8674(92)90263-C
1521:10.1016/0092-8674(92)90354-F
1477:10.1016/0092-8674(94)90248-8
1433:10.1016/0092-8674(95)90465-4
365:Academy of Medical Sciences
197:Christopher Francis Higgins
25:Christopher Francis Higgins
1940:
1860:2007–September 2014
1852:Warden and Vice-Chancellor
357:Royal Society of Edinburgh
260:in 1976. He was awarded a
1862:
1849:
1841:
1836:
383:Spongiform Encephalopathy
264:in 1979 for his study of
168:
101:
1414:Higgins, C. F. (1995).
1393:10.1126/science.8202710
1342:10.1126/science.1065588
548:(subscription required)
519:Higgins, Chris (2012).
234:Imperial College London
131:Imperial College London
280:, his focus turned to
61:Royal College of Music
361:Royal Society of Arts
302:University of Oxford
278:University of Dundee
268:transporters in the
256:, graduating with a
135:University of Dundee
127:University of Oxford
1904:English geneticists
1385:1994Sci...264.1578T
1379:(5165): 1578–1581.
1336:(5536): 1782–1784.
1291:1982Natur.298..723H
1239:1982Natur.298..760H
1188:1986Natur.321..253M
1137:1986Natur.323..448H
1085:1990Natur.344..789D
1034:1990Natur.346..362H
982:1991Natur.352..194H
931:1992Natur.355..830V
880:1993Natur.362..250H
828:1996Natur.381..169P
775:1997Natur.389Q.120M
720:1998Natur.391..291V
676:10.1038/nature05630
668:2007Natur.446..749H
620:. Durham University
479:1978Plant.138..217H
431:10.1104/pp.67.4.785
345:'Most Highly Cited'
214:molecular biologist
1845:Sir Kenneth Calman
487:10.1007/BF00386814
334:Sir Kenneth Calman
258:first class degree
1872:
1871:
1863:Succeeded by
1856:Durham University
1837:Academic offices
1285:(5876): 723–727.
1233:(5876): 760–762.
1182:(6067): 253–256.
1131:(6087): 448–450.
1079:(6268): 789–792.
1028:(6282): 362–365.
976:(6332): 194–195.
925:(6363): 830–833.
874:(6417): 250–255.
822:(6578): 169–172.
769:(6647): 120–121.
714:(6664): 291–295.
662:(7137): 749–757.
618:"Vice-Chancellor"
568:The Northern Echo
330:Durham University
254:Durham University
226:Durham University
194:
193:
123:Durham University
103:Scientific career
65:Durham University
1931:
1866:Stuart Corbridge
1842:Preceded by
1834:
1829:
1827:
1825:
1823:
1818:on 4 August 2007
1814:. Archived from
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419:Plant Physiology
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379:House of Commons
375:Select Committee
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160:Doctoral advisor
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332:. He succeeded
326:Vice-Chancellor
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272:of germinating
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222:Vice-Chancellor
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