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Christopher O. Barnes

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435:. Barnes used high-resolution imaging to better understand coronavirus spike proteins and the antibodies that attack them. He used cryo-electron microscopy, and identified several antibodies that attach to the receptor binding domain on the coronavirus spike protein. He defined an antibody classification system to determine where on the receptor binding domain that the antibody attaches. 180: 66: 25: 879: 874: 213: 869: 781: 478:
Christopher O Barnes; Claudia A Jette; Morgan E Abernathy; et al. (12 October 2020). "SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies".
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team. During his senior year, he was named the top student athlete. Although he had initially applied to study medicine, he changed his mind after being introduced to
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transcription using crystallographic techniques and electron microscopy. After earning his doctorate, Barnes started investigating the structure of
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of the topic and provide significant coverage of it beyond a mere trivial mention. If notability cannot be shown, the article is likely to be
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and the antibodies that attack it. He looked to understand how the virus contacts/enters cells to better inform the design of therapeutics.
829: 420: 316: 249: 231: 161: 142: 52: 114: 76: 461: 442:. These antibodies target the N-terminal domain. He is interested in identifying antibodies that can attack all coronaviruses. 199: 889: 121: 380: 87: 733: 376: 128: 523:"Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies" 399:. He was a bachelor's student in psychology, and moved to chemistry for his graduate studies. In 2010 he moved to the 83: 44: 110: 358: 99: 400: 295: 209: 830:"Stanford biologist named to 2022 class of Rita Allen Foundation Scholars | Stanford Humanities and Sciences" 195: 190: 864: 651: 859: 626: 439: 354: 320: 135: 428: 95: 601: 558: 540: 501: 493: 424: 388: 91: 609: 591: 583: 566: 548: 532: 509: 485: 480: 334:
MECHANISTIC INSIGHTS INTO EUKARYOTIC TRANSCRIPTION USING NOVEL CRYSTALLOGRAPHIC TECHNIQUES
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Christopher O Barnes; Anthony P West; Kathryn E Huey-Tubman; et al. (24 June 2020).
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Barnes continued to work on antibody structure when he established his own laboratory at
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and the antibodies that attack them. He was named one of ten "Scientists to watch" by
853: 757: 383:. As a teenager, he competed in the science olympiad. He was an undergraduate at the 447: 431:, who challenged him to uncover the structure of immune proteins that would attack 363: 706: 353:(born September 23, 1986) is an American chemist who is an assistant professor at 808: 179: 536: 587: 489: 432: 392: 544: 497: 613: 513: 404: 605: 578:
Zijun Wang; Fabian Schmidt; Yiska Weisblum; et al. (19 January 2021),
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mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants
333: 403:, where he started researching molecular pharmacology. He looked into 327: 734:"HHMI Selects 15 Hanna Gray Fellows to Support Diversity in Science" 82:
Please help to demonstrate the notability of the topic by citing
357:. During the COVID-19 pandemic, he studied the structure of the 408: 173: 59: 18: 707:"Christopher Barnes | School of Medicine Graduate Studies" 782:"Ask a Caltech Expert: Christopher Barnes on Antibodies" 205: 880:
Stanford University Department of Chemistry faculty
326: 312: 291: 271: 264: 875:University of North Carolina at Chapel Hill alumni 194:, potentially preventing the article from being 451:named Barnes one of ten "Scientists to watch". 8: 385:University of North Carolina at Chapel Hill 300:University of North Carolina at Chapel Hill 53:Learn how and when to remove these messages 261: 214:reliable, independent, third-party sources 595: 552: 250:Learn how and when to remove this message 232:Learn how and when to remove this message 162:Learn how and when to remove this message 870:People from Huntersville, North Carolina 419:Barnes was a postdoctoral researcher at 208:by replacing them with more appropriate 638: 191:too closely associated with the subject 656:University of North Carolina Athletics 7: 803: 801: 728: 726: 677: 675: 673: 671: 646: 644: 642: 625:Christopher is married to scientist 467:2022 Rita Allen Foundation Scholar 427:started. He was working alongside 421:California Institute of Technology 317:California Institute of Technology 77:notability guideline for academics 14: 387:, where he was involved with the 34:This article has multiple issues. 189:may rely excessively on sources 178: 64: 23: 652:"Christopher Barnes - Football" 462:Howard Hughes Medical Institute 42:or discuss these issues on the 885:21st-century American chemists 1: 381:North Mecklenburg High School 377:Huntersville, North Carolina 906: 828:MacCormick, Holly Alyssa. 537:10.1016/J.CELL.2020.06.025 84:reliable secondary sources 73:The topic of this article 588:10.1101/2021.01.15.426911 490:10.1038/S41586-020-2852-1 359:coronavirus spike protein 344: 305: 75:may not meet Knowledge's 786:Caltech Science Exchange 401:University of Pittsburgh 371:Early life and education 296:University of Pittsburgh 687:The Biophysical Society 111:"Christopher O. Barnes" 809:"SN 10 | Science News" 890:Structural biologists 472:Selected publications 351:Christopher O. Barnes 266:Christopher O. Barnes 758:"Christopher Barnes" 711:www.somgrad.pitt.edu 683:"Christopher Barnes" 464:Hanna H. Gray Fellow 834:humsci.stanford.edu 629:and has two sons. 440:Stanford University 415:Research and career 355:Stanford University 321:Stanford University 445:In September 2022 429:Pamela J. Bjorkman 375:Barnes grew up in 283:September 23, 1986 79: 455:Awards and honors 425:COVID-19 pandemic 389:American football 348: 347: 307:Scientific career 260: 259: 252: 242: 241: 234: 172: 171: 164: 146: 74: 57: 897: 844: 843: 841: 840: 825: 819: 818: 816: 815: 805: 796: 795: 793: 792: 778: 772: 771: 769: 768: 754: 748: 747: 745: 744: 730: 721: 720: 718: 717: 703: 697: 696: 694: 693: 679: 666: 665: 663: 662: 648: 616: 599: 574: 556: 517: 340: 286: 282: 280: 262: 255: 248: 237: 230: 226: 223: 217: 182: 174: 167: 160: 156: 153: 147: 145: 104: 68: 67: 60: 49: 27: 26: 19: 16:American chemist 905: 904: 900: 899: 898: 896: 895: 894: 850: 849: 848: 847: 838: 836: 827: 826: 822: 813: 811: 807: 806: 799: 790: 788: 780: 779: 775: 766: 764: 756: 755: 751: 742: 740: 732: 731: 724: 715: 713: 705: 704: 700: 691: 689: 681: 680: 669: 660: 658: 650: 649: 640: 635: 627:Naima G. Sharaf 623: 577: 520: 477: 474: 457: 417: 373: 338: 319: 298: 292:Alma mater 287: 284: 278: 276: 267: 256: 245: 244: 243: 238: 227: 221: 218: 203: 183: 168: 157: 151: 148: 105: 103: 81: 69: 65: 28: 24: 17: 12: 11: 5: 903: 901: 893: 892: 887: 882: 877: 872: 867: 862: 852: 851: 846: 845: 820: 797: 773: 749: 722: 698: 667: 637: 636: 634: 631: 622: 619: 618: 617: 575: 518: 473: 470: 469: 468: 465: 456: 453: 416: 413: 397:Gary J. Pielak 379:. He attended 372: 369: 346: 345: 342: 341: 330: 324: 323: 314: 310: 309: 303: 302: 293: 289: 288: 275: 273: 269: 268: 265: 258: 257: 240: 239: 186: 184: 177: 170: 169: 72: 70: 63: 58: 32: 31: 29: 22: 15: 13: 10: 9: 6: 4: 3: 2: 902: 891: 888: 886: 883: 881: 878: 876: 873: 871: 868: 866: 865:Living people 863: 861: 858: 857: 855: 835: 831: 824: 821: 810: 804: 802: 798: 787: 783: 777: 774: 763: 759: 753: 750: 739: 735: 729: 727: 723: 712: 708: 702: 699: 688: 684: 678: 676: 674: 672: 668: 657: 653: 647: 645: 643: 639: 632: 630: 628: 621:Personal life 620: 615: 611: 607: 603: 598: 593: 589: 585: 581: 576: 572: 568: 564: 560: 555: 550: 546: 542: 538: 534: 530: 529: 524: 519: 515: 511: 507: 503: 499: 495: 491: 487: 483: 482: 476: 475: 471: 466: 463: 459: 458: 454: 452: 450: 449: 443: 441: 436: 434: 430: 426: 422: 414: 412: 410: 406: 402: 398: 394: 390: 386: 382: 378: 370: 368: 366: 365: 360: 356: 352: 343: 336: 335: 331: 329: 325: 322: 318: 315: 311: 308: 304: 301: 297: 294: 290: 285:(age 38) 274: 270: 263: 254: 251: 236: 233: 225: 222:December 2022 215: 211: 207: 201: 197: 193: 192: 187:This article 185: 181: 176: 175: 166: 163: 155: 152:December 2022 144: 141: 137: 134: 130: 127: 123: 120: 116: 113: –  112: 108: 107:Find sources: 101: 97: 93: 89: 85: 78: 71: 62: 61: 56: 54: 47: 46: 41: 40: 35: 30: 21: 20: 837:. Retrieved 833: 823: 812:. Retrieved 789:. Retrieved 785: 776: 765:. Retrieved 761: 752: 741:. Retrieved 737: 714:. Retrieved 710: 701: 690:. Retrieved 686: 659:. Retrieved 655: 624: 579: 526: 479: 448:Science News 446: 444: 437: 418: 374: 364:Science News 362: 350: 349: 332: 313:Institutions 306: 246: 228: 219: 204:Please help 188: 158: 149: 139: 132: 125: 118: 106: 50: 43: 37: 36:Please help 33: 860:1986 births 88:independent 854:Categories 839:2022-12-04 814:2022-12-03 791:2022-12-04 767:2022-12-04 743:2022-12-04 716:2022-12-04 692:2022-12-04 661:2022-12-04 633:References 614:Q105098700 514:Q100524175 433:SARS-CoV-2 405:eukaryotic 393:biophysics 279:1986-09-23 206:improve it 196:verifiable 122:newspapers 96:redirected 39:improve it 571:Q97519832 545:0092-8674 498:1476-4687 423:when the 367:in 2022. 210:citations 86:that are 45:talk page 610:Wikidata 606:33501451 567:Wikidata 563:32645326 510:Wikidata 506:33045718 597:7836122 554:7311918 200:neutral 136:scholar 100:deleted 612:  604:  594:  569:  561:  551:  543:  512:  504:  496:  481:Nature 339:(2017) 337:  328:Thesis 138:  131:  124:  117:  109:  92:merged 460:2017 143:JSTOR 129:books 98:, or 762:HHMI 738:HHMI 602:PMID 559:PMID 541:ISSN 528:Cell 502:PMID 494:ISSN 272:Born 198:and 115:news 592:PMC 584:doi 549:PMC 533:doi 486:doi 409:HIV 395:by 212:to 856:: 832:. 800:^ 784:. 760:. 736:. 725:^ 709:. 685:. 670:^ 654:. 641:^ 608:, 600:, 590:, 582:, 565:. 557:. 547:. 539:. 531:. 525:. 508:. 500:. 492:. 484:. 281:) 94:, 48:. 842:. 817:. 794:. 770:. 746:. 719:. 695:. 664:. 586:: 573:. 535:: 516:. 488:: 277:( 253:) 247:( 235:) 229:( 224:) 220:( 216:. 202:. 165:) 159:( 154:) 150:( 140:· 133:· 126:· 119:· 102:. 80:. 55:) 51:(

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