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65:"Two Views of Mind" attempts to begin building a scientific basis for the effective application of technology to invoke, on-demand, the effects of deep meditation which would allow people to reach mental states previously attainable only by those with many years of focused training. Dr. deCharms has since gone on to develop and patent related technologies, described below.
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Subjects' brain activation patterns are measured using real-time fMRI as the subjects watch from inside the scanner using virtual reality goggles, and subjects are trained to control the patterns of activation inside their own brain. This in turn leads to changes in the subjects' mental experiences.
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DeCharms invented and patented the use of brain imaging for someone to visualize the functioning of their own brain in real time using fMRI , creating the new academic field of real-time neuroimaging-based training along with collaborators from around the world. He has developed a set of technologies
62:. The book included collaborations with a number of meditators and lamas, exploring how the approaches of the two traditions of Western Cognitive Neuroscience and Asian Introspective Meditation can be unified, and whether it is possible to use neuroscience to create new approaches to meditation.
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Keck Center for
Integrative Neuroscience. This work included recording patterns of brain activation from multiple locations in the brain, and how these patterns of activation underlie perception, experience, and learning. This has led to over three dozen published USPTO patent disclosures and
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DeCharms and a team of collaborative researchers have explored whether people can learn to control patterns of activation taking place inside their own brains. It had not previously been possible to non-invasively measure brain activation in real-time using neuroimaging, but recent advances in
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For example, subjects have learned to control activation in brain regions associated with pain, and they report a corresponding decrease in their levels of pain. DeCharms' team coined the term
Neuroimaging Therapy, in use to describe this approach.
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deCharms, R. C.; Christoff, K.; Glover, G. H.; Pauly, J. M.; Whitfield, S. & Gabrieli, J. D. (2004). "Learned regulation of spatially localized brain activation using real-time fMRI".
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Research on rtfMRI-based training has been published in the scientific literature and has also been broadly covered in the popular press including
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allowing patients, physicians, researchers, and subjects to visualize and control the functioning of the brain using non-invasive methods based on
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deCharms, R. C.; Merzenich, M. M. (1996). "Primary cortical representation of sounds by the coordination of action-potential timing".
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629:"Seeing Your Pain: Learning to consciously alter brain activity through MRI feedback could help control pain and other disorders"
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46:, including technology based on imaging methods that allow people to watch the activation of their own brains 'live' using
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multiple issued US patents by Dr. deCharms including foundational patents US-6996261, US-7567693, US-9241665 and others,
187:(rtfMRI). An overview of this field, applications of real-time functional brain imaging, is provided in Dr. deCharms'
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deCharms, R. C.; Blake, D. T. & Merzenich, M. M. (1998). "Optimizing sound features for cortical neurons".
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Miller, K. L.; Hargreaves, B. A.; Lee, J.; Ress, D.; deCharms, R. C. & Pauly, J. M. (2003).
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deCharms, R. C. & Zador, A. (2000). "Neural representation and the cortical code".
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232:, BBC, NPR, Wired, Technology Review. This research has been conducted at
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deCharms wrote the book Two Views of Mind, with the 14th Dalai Lama,
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computation and neuroimaging have made this a reality using rtfMRI.
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Christopher deCharms - The Future Of The Mind (LeWeb'14 Paris)
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Christopher deCharms: A look inside the brain in real time
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and more recently at
Omneuron's 3T MRI Research Center in
38:. Currently, Dr. deCharms is the founder and CEO of
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Proceedings of the
National Academy of Sciences USA
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Proceedings of the
National Academy of Sciences USA
587:Two Views of Mind: Abhidharma and Brain Science
185:real-time functional magnetic resonance imaging
721:University of California, San Francisco alumni
210:https://patents.justia.com/patent/20160267809
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191:. DeCharms started his research career in
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170:Learn how and when to remove this message
605:"Mind Over Matter with a Machine's Help"
258:; Ludlow, D.; Pauly, J. M.; Soneji, D.;
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240:, California through funding from the
48:functional magnetic resonance imaging
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331:10.1016/j.neuroimage.2003.08.041
195:as a graduate student and later
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54:Augmented Meditation Technology
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361:Magnetic Resonance in Medicine
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509:10.1126/science.280.5368.1439
402:Annual Review of Neuroscience
242:National Institutes of Health
262:& Mackey, S. C. (2005).
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88:biography of a living person
108:must be removed immediately
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716:American neuroscientists
459:10.1073/pnas.95.26.15166
430:deCharms, R. C. (1998).
24:Dr. Christopher deCharms
289:10.1073/pnas.0505210102
197:postdoctoral researcher
119:"Christopher deCharms"
102:Please help by adding
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248:Selected publications
199:in the laboratory of
97:references or sources
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671:Christopher deCharms
540:1996Natur.381..610D
501:1998Sci...280.1439C
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234:Stanford University
655:Omneuron's website
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230:The New York Times
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