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240:. Spanning the fields of science and medicine, he was Canada's first medical geneticist, one of the creators of the discipline of medical genetics in North America, and laid the foundations in the field of Genetic Counselling, which has enhanced the lives of patients worldwide. Among his many accomplishments, Fraser pioneered work in the genetics of cleft palate and popularized the concept of multifactorial disease.
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Before Fraser took the stage, genetics and medicine were two very separate fields. There was no vision for the potential of genetics in human medicine. But very soon, Fraser turned his attention from fruit flies and mice to human genetics, and became the founder of the first
Canadian medical genetics
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Fraser made contributions in three areas. He collected data on recurrence risks for a number of pediatric conditions, to answer the questions of the parents of affected children. He helped develop the principles of genetic counseling. He showed that cortisone, injected into pregnant mice, caused
252:, he returned with his family to Canada when he was an infant. After a few years in Dublin, where his father, Frank Wise Fraser was Canadian Trade Commissioner, the family moved to Jamaica, where he received his primary and secondary school education at
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cleft palates in the offspring, and that the frequency of induced clefts varied with the genotype, thus bringing genetics into teratology. From this he developed the multifactorial threshold model that underlies many common familial conditions.
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He has been awarded four honorary doctorates, from Acadia
University (1967), SUNY at Potsdam, Dalhousie University (2003) and McGill University (2010).
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1979 Founding co-director of the
Medical Research Council of Canada Group in Medical Genetics, the longest lasting group in the history of the MRC.
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Fraser has served as president of the major North
American societies in Genetics and Teratology and has won almost every award in his field.
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department in a paediatric hospital, named the F. Clarke Fraser
Clinical Genetics Centre at McGill University in 1995.
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453:"Obituary: Clarke Fraser made pioneering discoveries in McGill's 'mouse room'"
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1952-82 Founder and
Director of the Department of Medical Genetics at the
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1970-82 was the Molson
Professor of Genetics in the Department of Biology.
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1950: joined McGill
University as an assistant professor of genetics.
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1955: appointed an
Associate and in 1960 was made a full professor.
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Multifactorial threshold model that underlies some familial conditions
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1979–82, Professor in the McGill Centre for Human Genetics.
236:(29 March 1920 – 17 December 2014) was a Canadian medical
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Academic staff of the Memorial University of Newfoundland
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321:1982–85, Professor of Clinical Genetics at
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1486:Canadian expatriates in the United States
69:Learn how and when to remove this message
519:Osler Library of the History of Medicine
32:This article includes a list of general
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1451:Fellows of the Royal Society of Canada
483:archivalcollections.library.mcgill.ca
7:
1461:Academic staff of McGill University
323:Memorial University of Newfoundland
38:it lacks sufficient corresponding
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1481:People educated at Munro College
1476:People from Norwich, Connecticut
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1471:Officers of the Order of Canada
418:"Canadian Medical Hall of Fame"
380:"Canadian Who's Who 1997 entry"
451:Fitterman, Lisa (2015-01-21).
350:1999 Government of Quebec's
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561:Canadian Medical Hall of Fame
359:Canadian Medical Hall of Fame
316:Montreal Children's Hospital
1400:Marie-Marguerite d'Youville
384:University of Toronto Press
16:Canadian medical geneticist
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1130:Jonathan Campbell Meakins
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510:The Canadian Encyclopedia
288:but did not go overseas.
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107:Norwich, Connecticut, USA
1436:Acadia University alumni
1240:Cheryl Rockman-Greenberg
1175:William Thornton Mustard
1042:Charles Philippe Leblond
479:"F. Clarke Fraser Fonds"
286:Royal Canadian Air Force
212:Royal Canadian Air Force
738:William Arthur Cochrane
338:Royal Society of Canada
53:more precise citations.
1341:Lucille Teasdale-Corti
1155:Frederick Montizambert
660:Wilfred Gordon Bigelow
515:F. Clarke Fraser fonds
357:2012 Elected to the
343:1984 Officer of the
336:1966 Fellow of the
1441:Canadian geneticists
1298:F. Estelle R. Simons
796:Charles George Drake
723:Harvey Max Chochinov
352:Prix Wilder-Penfield
276:degree in 1950 from
260:degree in 1940 from
250:Norwich, Connecticut
1446:Medical geneticists
1255:Jean-Lucien Rouleau
943:Emmett Matthew Hall
753:Douglas Harold Copp
615:Charles Thomas Beer
605:Henry J. M. Barnett
559:Inductees into the
506:Frank Clarke Fraser
284:, he served in the
258:Bachelor of Science
225:Frank Clarke Fraser
214:, McGill University
187:William Allan Award
85:Frank Clarke Fraser
1361:Sir Charles Tupper
1303:Duncan G. Sinclair
1165:Thomas John Murray
993:Charles B. Huggins
978:Charles Hollenberg
958:Donald Olding Hebb
948:Judith Goslin Hall
933:Vladimir Hachinski
857:John G. FitzGerald
635:Michel G. Bergeron
458:The Globe and Mail
274:Doctor of Medicine
268:degree in 1941, a
203:Medicine, genetics
165:Medical geneticist
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595:Elizabeth Bagshaw
523:McGill University
278:McGill University
266:Master of Science
262:Acadia University
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194:Scientific career
155:McGill University
147:Acadia University
116:December 17, 2014
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486:. Retrieved
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428:November 23,
426:. Retrieved
422:the original
406:. Retrieved
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387:. Retrieved
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282:World War II
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208:Institutions
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118:(2014-12-17)
65:
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37:
1431:2014 deaths
1426:1920 births
1405:Salim Yusuf
1328:Emily Stowe
1224:Vera Peters
1135:Maud Menten
1115:Marco Marra
1110:Tak Wah Mak
1100:John McCrae
988:David Hubel
758:Max Cynader
728:Bruce Chown
700:John Browne
610:Murray Barr
408:October 13,
389:October 13,
151:Nova Scotia
125:Nationality
51:introducing
1420:Categories
1346:James Till
1288:Hans Selye
1265:Ian Rusted
1260:Claude Roy
973:Jack Hirsh
781:John Dirks
766:Paul David
488:2018-03-28
464:2015-01-27
438:References
238:geneticist
161:Occupation
100:1920-03-29
59:April 2014
34:references
915:Jean Gray
905:Phil Gold
867:Terry Fox
743:May Cohen
280:. During
244:Biography
135:Education
620:John Bel
248:Born in
129:Canadian
88:OC, FRSC
517:at the
143:Jamaica
47:improve
200:Fields
179:Awards
36:, but
270:Ph.D.
231:
430:2011
410:2006
391:2006
264:, a
233:FRSC
113:Died
94:Born
508:at
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