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Kaposi's sarcoma

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699: 711: 723: 474: 680: 598: 426: 1160:, in which the main character was fired after his employers found out he was HIV-positive due to visible lesions. By the time KS lesions appear, likely, the immune system has already been severely weakened. It has been reported that only 6% of men who have sex with men are aware that KS is caused by a virus different from HIV. Thus, there is little community effort to prevent KSHV infection. Likewise, no systematic screening of organ donations is in place. 418: 43: 1058: 2166:
Parravicini C, Olsen SJ, Capra M, Poli F, Sirchia G, Gao SJ, Berti E, Nocera A, Rossi E, Bestetti G, Pizzuto M, Galli M, Moroni M, Moore PS, Corbellino M (October 1997). "Risk of Kaposi's sarcoma-associated herpes virus transmission from donor allografts among Italian posttransplant Kaposi's sarcoma
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Blood tests to detect antibodies against KSHV have been developed and can be used to determine whether a person is at risk for transmitting the infection to their sexual partner, or whether an organ is infected before transplantation. However, these tests are not available except as research tools,
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Classic, endemic, immunosuppression therapy-related (also known as iatrogenic), and epidemic (also known as AIDS-related) sub-types are all described. Classic KS tends to affect older men in regions where KSHV is highly prevalent (Mediterranean, Eastern Europe, Middle East), is usually slow-growing,
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and may be flat or raised. Lesions can occur singly, multiply in a limited area, or may be widespread. Depending on the sub-type of disease and level of immune suppression, KS may worsen either gradually or quickly. Except for Classical KS where there is generally no immune suppression, KS is caused
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most commonly appears early on the toes and soles as reddish, violaceous, or bluish-black macules and patches that spread and coalesce to form nodules or plaques. A small percentage of these patients may have visceral lesions. In most cases the treatment involves surgical removal of the lesion. The
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patients in the 1980s, when its incidence grew rapidly. The tumor arises either when an HHV 8-infected organ is transplanted into someone who has not been exposed to the virus or when the transplant recipient already harbors pre-existing HHV 8 infection. Unlike classic Kaposi sarcoma, the site of
1005:, may induce regression of localized lesions in classic as well as HIV-associated Kaposi sarcoma. In general, surgery is not recommended, as Kaposi sarcoma can appear in wound edges. In general, more widespread disease, or disease affecting internal organs, is treated with systemic therapy with 585:
In Europe and North America, KSHV is transmitted through saliva. Thus, kissing is a risk factor for transmission. Higher rates of transmission among gay and bisexual men have been attributed to "deep kissing" sexual partners with KSHV. Another alternative theory suggests that use of saliva as a
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With the decrease in the death rate among people with HIV/AIDS receiving new treatments in the 1990s, the rates and severity of epidemic KS also decreased. However, the number of people living with HIV/AIDS is increasing in the United States, and it is possible that the number of people with
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Weninger W, Partanen TA, Breiteneder-Geleff S, Mayer C, Kowalski H, Mildner M, et al. (February 1999). "Expression of vascular endothelial growth factor receptor-3 and podoplanin suggests a lymphatic endothelial cell origin of Kaposi's sarcoma tumor cells".
722: 986:(HAART). Therefore, HAART is considered the cornerstone of therapy in AIDS-associated Kaposi sarcoma. However, in a certain percentage of such people, Kaposi sarcoma may recur after many years on HAART, especially if HIV is not completely suppressed. 325:
and most often affects only the legs. Endemic KS is most common in Sub-Saharan Africa and is more aggressive in children, while older adults present similarly to classic KS. Immunosuppression therapy-related KS generally occurs in people following
954:. In more advanced cases, lesions can be found in the stomach and intestines, the lymph nodes, and the lungs. Compared to other forms of KS, KS-AIDS stimulated more interest in KS research, as it was one of the first illnesses associated with 5680: 5665: 3212:
Gill PS, Tulpule A, Espina BM, Cabriales S, Bresnahan J, Ilaw M, Louie S, Gustafson NF, Brown MA, Orcutt C, Winograd B, Scadden DT (June 1999). "Paclitaxel is safe and effective in the treatment of advanced AIDS-related Kaposi's sarcoma".
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or immunosuppression, treating the cause of the immune system dysfunction can slow or stop the progression of KS. In 40% or more of patients with AIDS-associated Kaposi sarcoma, the Kaposi lesions will shrink upon first starting
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and first described in 1981. This form of KS is over 300 times more common in AIDS patients than in renal transplant recipients. In this case, HHV 8 is sexually transmitted among people also at risk for sexually transmitted HIV
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Involvement can be common in those with transplant-related or AIDS-related KS, and it may occur in the absence of skin involvement. The gastrointestinal lesions may be silent or cause weight loss, pain, nausea/vomiting,
642:. The most typical feature of Kaposi sarcoma is the presence of spindle cells forming slits containing red blood cells. Mitotic activity is only moderate and pleomorphism is usually absent. The tumor is highly 3396: 586:
sexual lubricant might be a major mode for transmission. Prudent advice is to use commercial lubricants when needed and avoid deep kissing with partners with KSHV infection or whose status is unknown.
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Tappero JW, Berger TG, Kaplan LD, Volberding PA, Kahn JO (1991). "Cryotherapy for cutaneous Kaposi's sarcoma (KS) associated with acquired immune deficiency syndrome (AIDS): a phase II trial".
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Because of their highly visible nature, external lesions are sometimes the presenting symptom of AIDS. Kaposi sarcoma entered the awareness of the general public with the release of the film
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first described the cancer, the disease has been reported in five separate clinical settings, with different presentations, epidemiology, and prognoses. All of the forms are infected with
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Treatment is based on the sub-type, whether the condition is localized or widespread, and the person's immune function. Localized skin lesions may be treated by surgery, injections of
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KSHV is also transmissible via organ transplantation and blood transfusion. Testing for the virus before these procedures is likely to effectively limit iatrogenic transmission.
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and forms vascular channels that fill with blood cells, giving the tumor its characteristic bruise-like appearance. KSHV proteins are uniformly detected in KS cancer cells.
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The condition is relatively common in people with HIV/AIDS and following organ transplant. Over 35% of people with AIDS may be affected. KS was first described by
5817: 5611: 3896: 5812: 4609: 4529: 5414: 3124:"Propranolol Decreases Proliferation of Endothelial Cells Transformed by Kaposi's Sarcoma-Associated Herpesvirus and Induces Lytic Viral Gene Expression" 5085: 899:
presents with nodular, infiltrative, vascular masses on the extremities, mostly in men between the ages of 20 and 50, and is endemic in tropical Africa.
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Fenig E, Brenner B, Rakowsky E, Lapidoth M, Katz A, Sulkes A (October 1998). "Classic Kaposi sarcoma: experience at Rabin Medical Center in Israel".
646:, containing abnormally dense and irregular blood vessels, which leak red blood cells into the surrounding tissue and give the tumor its dark color. 4821: 2194:
Hladik W, Dollard SC, Mermin J, Fowlkes AL, Downing R, Amin MM, Banage F, Nzaro E, Kataaha P, Dondero TJ, Pellett PE, Lackritz EM (September 2006).
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Luppi M, Barozzi P, Schulz TF, Setti G, Staskus K, Trovato R, Narni F, Donelli A, Maiorana A, Marasca R, Sandrini S, Torelli G (November 2000).
4765: 4203: 360:(HAART) prevents and often treats KS. In certain cases the addition of chemotherapy may be required. With widespread disease, death may occur. 2084:. Manipulation of the immune response by Epstein-Barr virus and Kaposi's sarcoma-associated herpes virus: Consequences for tumor development. 716:
Micrograph of plaque stage, with bizarre vessels dissecting the upper dermis. There is erythrocyte extravasation and hemosiderin pigmentation.
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Sgadari C, Toschi E, Palladino C, Barillari G, Carlei D, Cereseto A, Ciccolella C, Yarchoan R, Monini P, Stürzl M, Ensoli B (July 2000).
5706: 4814: 2767:"Increasing Kaposi's sarcoma-associated herpesvirus seroprevalence with age in a highly Kaposi's sarcoma endemic region, Zambia in 1985" 2718:"Increasing Kaposi's sarcoma-associated herpesvirus seroprevalence with age in a highly Kaposi's sarcoma endemic region, Zambia in 1985" 4646: 3985: 3289: 738:
Although KS may be suspected from the appearance of lesions and the patient's risk factors, a definite diagnosis can be made only by
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Micrograph of promontory sign in Kaposi's sarcoma in patch stage. Dilated irregular vascular channels surround a pre-existing vessel.
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Micrograph of tumor stage. Well-circumscribed spindle-cell tumor. Erythrocytes lie within poorly defined slit-like vascular spaces.
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Borkovic SP, Schwartz RA (December 1981). "Kaposi's sarcoma presenting in the homosexual man -- a new and striking phenomenon!".
2299:"Mesenchymal-to-endothelial transition in Kaposi sarcoma: a histogenetic hypothesis based on a case series and literature review" 1122: 969:
and, thus, there is little screening for persons at risk for becoming infected with KSHV, such as people following a transplant.
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is aggressive, occurring in children under 10 years of age, presenting with lymph node involvement, with or without skin lesions.
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and are different manifestations of the same disease but have differences in clinical aggressiveness, prognosis, and treatment.
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is more effective than either of those two therapies individually. Limited basic and clinical evidence suggest that topical
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The mouth is involved in about 30% of cases, and is the initial site in 15% of AIDS-related KS. In the mouth, the
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of a Kaposi sarcoma showing the characteristic spindle cells, high vascularity, and intracellular hyaline globs.
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Ensoli B, Sirianni MC (1998). "Kaposi's sarcoma pathogenesis: a link between immunology and tumor biology".
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Garay SM, Belenko M, Fazzini E, Schinella R (January 1987). "Pulmonary manifestations of Kaposi's sarcoma".
1164: 550:, when the lesions are directly seen and often biopsied. Kaposi's sarcoma of the lung has a poor prognosis. 5011: 4977: 4717: 4680: 4636: 4604: 4422: 4334: 3650: 983: 908: 812: 597: 515: 391: 357: 221: 4806: 2814:
Qunibi W, Al-Furayh O, Almeshari K, Lin SF, Sun R, Heston L, Ross D, Rigsby M, Miller G (February 1998).
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Dezube BJ (October 1996). "Clinical presentation and natural history of AIDS--related Kaposi's sarcoma".
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Pauk J, Huang ML, Brodie SJ, Wald A, Koelle DM, Schacker T, Celum C, Selke S, Corey L (November 2000).
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People with a few local lesions can often be treated with local measures such as radiation therapy or
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Blumenfeld W, Egbert BM, Sagebiel RW (February 1985). "Differential diagnosis of Kaposi's sarcoma".
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Schwartz RA, Micali G, Nasca MR, Scuderi L (August 2008). "Kaposi sarcoma: a continuing conundrum".
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Kaposi sarcoma is not curable, but it can often be treatable for many years. In KS associated with
318: 194: 2582:"Classic Kaposi's sarcoma in Jews living in Israel, 1961-1989: a population-based incidence study" 425: 5333: 5222: 5076: 4939: 4904: 4874: 4702: 4567: 4241: 4105: 3990: 3949: 3823: 3818: 3813: 3640: 3028: 2985: 2796: 2747: 2611: 2009: 1699: 1644: 1547: 1175:, where KSHV is widespread, KS has become the most frequently reported cancer in some countries. 1172: 880: 817: 754: 539: 230: 168: 5621: 5212: 1115: 1044:
AIDS-associated Kaposi sarcoma will again rise as these people live longer with HIV infection.
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They are typically found on the skin, but spread elsewhere is common, especially the mouth,
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Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, Moore PS (December 1994).
951: 802: 398:. Growth can range from very slow to explosively fast, and is associated with significant 338: 214: 2857:"Bone marrow failure associated with human herpesvirus 8 infection after transplantation" 409:
The lesions are painless, but become cosmetically disfiguring or interruptive to organs.
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Characteristic purple lesions of Kaposi's sarcoma on the nose of an HIV-positive female.
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positive hyaline bodies are often seen in the cytoplasm or sometimes extracellularly.
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Phillips AM, Jones AG, Osmond DH, Pollack LM, Catania JA, Martin JN (December 2008).
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Patch stage Kaposi's sarcoma. Red to brownish irregularly shaped macules and plaques.
364: 334: 210: 5689: 3032: 2989: 2615: 2093: 2013: 1920: 1703: 1648: 5768: 5556: 5388: 5311: 5301: 5248: 5208: 5199: 5047: 4795: 4790: 4725: 4501: 4372: 3944: 3924: 3739: 3734: 3724: 3565: 3090: 2800: 2751: 2078:"Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis" 1551: 1032: 1018: 998: 994: 862: 777: 662: 647: 643: 617: 574: 547: 454: 345: 249: 2275: 2044: 689: 465:
by the lesion). Kaposi's sarcoma skin lesions may be psychologically distressing.
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are nodules or blotches that may be red, purple, brown, or black, and are usually
42: 5722: 3334: 2323: 1804: 5752: 5545: 4695: 4579: 4407: 4232: 3934: 3600: 2873: 2856: 2143: 2126: 1057: 1022: 1014: 990: 912: 628: 543: 490: 482: 458: 434: 297: 189: 5771: 3266: 3249: 3226: 3189: 3172: 2236: 1780:"Non-AIDS associated Kaposi's sarcoma: clinical features and treatment outcome" 1393: 5785: 5780: 5774: 5733: 5575: 5531: 5188: 5107: 4986: 4621: 4367: 4208: 4085: 3803: 3775: 3545: 3173:"Classic and HIV-related Kaposi sarcoma treated with 0.1% topical timolol gel" 1479: 1323: 1026: 1006: 854: 685: 670: 613: 601: 562: 535: 2958:"Kaposi's sarcoma among persons with AIDS: a sexually transmitted infection?" 1854: 1462:
Cesarman E, Damania B, Krown SE, Martin J, Bower M, Whitby D (January 2019).
481:-positive person presenting with a Kaposi's sarcoma lesion with an overlying 5763: 5674: 5496: 5459: 5343: 4929: 4853: 4412: 4362: 4126: 3713: 3685: 3590: 3425: 2557: 2540: 1687: 625: 570: 566: 438: 403: 4462: 3352: 3275: 3234: 3198: 3157: 3108: 3059: 2882: 2566: 2436: 2342: 2221: 2152: 2111: 2062: 1838: 1823: 1543: 1497: 1401: 1341: 1229: 849:
condition tends to be indolent and chronic, affecting elderly men from the
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and other vascular proliferations can be microscopically confused with KS.
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Sand M, Sand D, Thrandorf C, Paech V, Altmeyer P, Bechara FG (June 2010).
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that promote cancer cell proliferation and escape from the immune system.
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Iscovich J, Boffetta P, Winkelmann R, Brennan P, Azizi E (October 1998).
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Griffiths C, Barker J, Bleiker TO, Chalmers R, Creamer D (4 April 2016).
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and is a more aggressive disease that infiltrates the skin extensively.
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Collins English Dictionary – Complete and Unabridged, 12th Edition 2014
1082: in this section. Unsourced material may be challenged and removed. 1002: 807: 609: 510:, bleeding (either vomiting blood or passing it with bowel movements), 5657: 2425:
Laboratory Investigation; A Journal of Technical Methods and Pathology
1534: 1517: 441:. The lesions are usually as described above, but may occasionally be 5669: 5156: 4914: 4894: 4747: 3848: 3793: 3560: 3555: 3529: 3438: 939: 935: 931: 916: 739: 621: 384: 380: 305: 301: 289: 173: 2957: 1624: 3046:
Zimmerman EE, Crawford P (December 2012). "Cutaneous cryosurgery".
1663: 4841: 3514: 1957:(June 1991). "Gastrointestinal malignancy in patients with AIDS". 771: 531: 527: 472: 424: 416: 2765:
Olsen SJ, Chang Y, Moore PS, Biggar RJ, Melbye M (October 1998).
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Olsen SJ, Chang Y, Moore PS, Biggar RJ, Melbye M (October 1998).
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Cook-Mozaffari P, Newton R, Beral V, Burkitt DP (December 1998).
5711: 5297: 5149: 4095: 3614: 3433: 2541:"Classic Kaposi's sarcoma in Arabs--widening ethnic involvement" 2297:
Gurzu S, Ciortea D, Munteanu T, Kezdi-Zaharia I, Jung I (2008).
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around the tumor may produce swelling and pain. Variously sized
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Involvement of the airway can present with shortness of breath,
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in the 1980s. KSHV was discovered as a causative agent in 1994.
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Abdelmaksoud A, Filoni A, Giudice G, Vestita M (January 2017).
2241:. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. 333:
and many parts of the body can be affected. KS is diagnosed by
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and mostly affects the skin. Epidemic KS occurs in people with
3075:"Treatment of Kaposi sarcoma in children with HIV-1 infection" 2027:
Ablashi DV, Chatlynne LG, Whitman JE, Cesarman E (July 2002).
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Cancer of the skin, integumentary lymph nodes, or other organs
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Beral V, Peterman TA, Berkelman RL, Jaffe HW (January 1990).
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Classic, endemic, immunosuppression therapy-related, epidemic
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and microscopic examination. Detection of the KSHV protein
445:-like (often on the soles of the feet) or even involved in 140: 119: 113: 84: 78: 2941:
Drabell FG (2006). "Kaposi's Sarcoma and Renal Diseases".
2196:"Transmission of human herpesvirus 8 by blood transfusion" 1260:. S.v. "Kaposi's sarcoma." Retrieved August 15, 2017 from 1245:. S.v. "Kaposi's sarcoma." Retrieved August 15, 2017 from 1876:
França, Katlein; Jafferany, Mohammad (16 December 2016).
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The spindle cells of Kaposi sarcoma differentiate toward
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Despite its name, in general it is not considered a true
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had been described, but only rarely until the advent of
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Anglemyer A, Agrawal AK, Rutherford GW (January 2014).
1905:"Treating Kaposi's lesions in the HIV-infected patient" 638:
with a characteristic abnormal elongated shape, called
321:(HHV8 – also called KS-associated herpesvirus (KSHV)). 3250:"Mechanism of paclitaxel activity in Kaposi's sarcoma" 3122:
McAllister SC, Hanson RS, Manion RD (November 2015).
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Stress and Skin Disorders: Basic and Clinical Aspects
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http://www.thefreedictionary.com/Kaposi's+sarcoma
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http://www.thefreedictionary.com/Kaposi's+sarcoma
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In people with AIDS, Kaposi sarcoma is considered an
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HHV-8 is responsible for all varieties of KS. Since
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Andrews' Diseases of the Skin: Clinical Dermatology
1778:Jakob L, Metzler G, Chen KM, Garbe C (April 2011). 1258:
Random House Kernerman Webster's College Dictionary
367:in 1872. It became more widely known as one of the 337:, while the extent of disease may be determined by 271: 263: 244: 220: 204: 188: 180: 167: 155: 128: 101: 72: 54: 35: 1568:Ferri's Clinical Advisor 2018 E-Book: 5 Books in 1 3412:Diseases of the skin and appendages by morphology 1903:Nichols CM, Flaitz CM, Hicks MJ (November 1993). 1625:"Idiopathisches multiples Pigmentsarkom der Haut" 604:of a Kaposi sarcoma showing its typical features. 2127:"Mucosal shedding of human herpesvirus 8 in men" 865:have a higher rate of KSHV/HHV-8 infection than 665:rather than blood vessel origin. The consistent 4708:Intravascular papillary endothelial hyperplasia 3005:Journal of Acquired Immune Deficiency Syndromes 2452:Archives of Pathology & Laboratory Medicine 934:that begin as one or several red to purple-red 620:of KS remains controversial. KS may arise as a 453:. Associated swelling may be from either local 36:Kaposi's sarcoma, multiple haemorrhagic sarcoma 3177:Journal of the American Academy of Dermatology 2508: 2506: 2504: 2502: 2500: 2498: 2356:Beckstead JH, Wood GS, Fletcher V (May 1985). 1382:Journal of the American Academy of Dermatology 5612:Asymmetric periflexural exanthem of childhood 4822: 4478: 3897:Pityriasis lichenoides et varioliformis acuta 3397: 1592: 1590: 1588: 673:supports the lymphatic nature of the lesion. 493:is most frequently affected, followed by the 8: 3551:Dermatofibroma (benign fibrous histiocytoma) 1773: 1771: 1769: 1767: 1719:Hematology/Oncology Clinics of North America 3079:The Cochrane Database of Systematic Reviews 2545:Journal of Cancer Research and Therapeutics 1308:"Diagnosis and Treatment of Kaposi Sarcoma" 1283: 1281: 1279: 1277: 1275: 1273: 1271: 1269: 905:Immunosuppression-associated Kaposi sarcoma 5648: 5464: 5415:Papular purpuric gloves and socks syndrome 5283: 5113: 4880: 4869: 4858: 4849: 4829: 4815: 4807: 4485: 4471: 4463: 4274: 4172: 4044: 4033: 4026: 3630: 3619: 3421: 3404: 3390: 3382: 2076:Liang C, Lee JS, Jung JU (December 2008). 1909:Journal of the American Dental Association 1511: 1509: 1507: 1375: 1373: 1371: 761:Differential diagnosis of Kaposi's sarcoma 41: 32: 3342: 3265: 3188: 3147: 3098: 2872: 2831: 2782: 2733: 2692: 2597: 2556: 2373: 2332: 2322: 2211: 2142: 2101: 2052: 1813: 1803: 1571:. Elsevier Health Sciences. p. 735. 1533: 1516:Hoffmann C, Sabranski M, Esser S (2017). 1487: 1413: 1411: 1369: 1367: 1365: 1363: 1361: 1359: 1357: 1355: 1353: 1351: 1331: 1219: 1209: 1142:Learn how and when to remove this message 304:. The skin lesions are usually painless, 2235:Coffin JM, Hughes SH, Varmus HE (1997). 1959:The American Journal of Gastroenterology 1312:American Journal of Clinical Dermatology 1306:Schneider JW, Dittmer DP (August 2017). 596: 546:. The diagnosis is usually confirmed by 5086:Kaposi's sarcoma-associated herpesvirus 3370:Kaposi sarcoma photo library at Dermnet 2399:Rosai and Ackerman's Surgical Pathology 1837:Holland, J. C.; Tross, S. (June 1987). 1184: 891:African lymphadenopathic Kaposi sarcoma 746:in tumor cells confirms the diagnosis. 675: 559:Kaposi's sarcoma-associated herpesvirus 4766:Multifocal lymphangioendotheliomatosis 4204:Disseminated intravascular coagulation 1418:The Global Cancer Observatory (2019). 2631:American Journal of Clinical Oncology 1754:Taber's Cyclopedic Medical Dictionary 7: 5818:Connective and soft tissue neoplasms 5617:Post-vaccination follicular eruption 4563:Proliferating angioendotheliomatosis 3290:"Summary of Product Characteristics" 2513:James W, Berger T, Elston D (2005). 1629:Archiv für Dermatologie und Syphilis 1457: 1455: 1453: 1451: 1449: 1447: 1445: 1443: 1441: 1439: 1171:has been weakened. With the rise of 1080:adding citations to reliable sources 984:highly active antiretroviral therapy 433:Commonly affected areas include the 358:highly active antiretroviral therapy 2861:The New England Journal of Medicine 2200:The New England Journal of Medicine 2131:The New England Journal of Medicine 5813:Virus-related cutaneous conditions 3986:Postinflammatory hyperpigmentation 2945:. New York: Nova Biomedical Books. 930:typically presents with cutaneous 25: 4740:Acquired progressive lymphangioma 3887:Transient acantholytic dermatosis 2481:(Ninth ed.). p. 31.29. 2362:The American Journal of Pathology 1953:Danzig JB, Brandt LJ, Reinus JF, 1518:"HIV-Associated Kaposi's Sarcoma" 883:. This variant is not related to 5632:Viral-associated trichodysplasia 5017:Modified varicella-like syndrome 4840:, symptoms and signs related to 3996:Idiopathic guttate hypomelanosis 3017:10.1097/00126334-199109000-00002 2833:10.1097/00007890-199802270-00024 2784:10.1097/00002030-199814000-00024 2735:10.1097/00002030-199814000-00024 2643:10.1097/00000421-199810000-00016 2599:10.1097/00002030-199815000-00019 1056: 897:African cutaneous Kaposi sarcoma 721: 709: 697: 678: 612:, which is a tumor arising from 97: 62: 5339:Epidermodysplasia verruciformis 4515:Blue rubber bleb nevus syndrome 4006:Hypopigmented mycosis fungoides 2928:Infections Causing Human Cancer 2264:Critical Reviews in Oncogenesis 2094:10.1016/j.semcancer.2008.09.003 1921:10.14219/jada.archive.1993.0231 1522:Oncology Research and Treatment 1468:Nature Reviews. Disease Primers 1194:"Cutaneous lesions of the nose" 1067:needs additional citations for 227:Blue rubber bleb nevus syndrome 5354:Verrucae palmares et plantares 4247:Lichen sclerosis et atrophicus 3955:Subcorneal pustular dermatosis 3581:Infantile digital fibromatosis 3091:10.1002/14651858.CD009826.pub2 2479:Rook's textbook of dermatology 928:AIDS-associated Kaposi sarcoma 924:presentation is more variable. 421:An example of Kaposi's sarcoma 1: 5571:Hand, foot, and mouth disease 5066:Cytomegalic inclusion disease 3839:Epidermolysis bullosa simplex 3676:Langerhans cell histiocytosis 3323:Sexually Transmitted Diseases 2943:New Topics in Cancer Research 2276:10.1615/CritRevOncog.v9.i2.20 2045:10.1128/cmr.15.3.439-464.2002 2033:Clinical Microbiology Reviews 1731:10.1016/S0889-8588(05)70382-8 5583:Foot-and-mouth disease virus 4610:Immunosuppression-associated 4573:Infantile hemangiopericytoma 4315:Systemic lupus erythematosus 4070:Systemic lupus erythematosus 3761:Systemic lupus erythematosus 3335:10.1097/OLQ.0b013e318182c91f 3215:Journal of Clinical Oncology 2974:10.1016/0140-6736(90)90001-L 2324:10.1371/journal.pone.0071530 1805:10.1371/journal.pone.0018397 300:, in the mouth, or in other 292:that can form masses on the 5627:Eruptive pseudoangiomatosis 5518:Congenital rubella syndrome 5263:Molluscum contagiosum virus 4735:Lymphangioma circumscriptum 3596:Lymphangioma circumscriptum 2874:10.1056/NEJM200011093431905 2517:(10th ed.). Saunders. 2144:10.1056/NEJM200011093431904 751:arteriovenous malformations 749:In differential diagnosis, 5844: 5007:Disseminated herpes zoster 4945:Herpetic gingivostomatitis 4418:Mucous membrane pemphigoid 3267:10.4049/jimmunol.165.1.509 3227:10.1200/jco.1999.17.6.1876 3190:10.1016/j.jaad.2016.08.041 2926:(2006). "Rhadinoviruses". 2082:Seminars in Cancer Biology 1598:"Kaposi Sarcoma Treatment" 1394:10.1016/j.jaad.2008.05.001 1388:(2): 179–206, quiz 207–8. 1289:"Kaposi Sarcoma Treatment" 915:, which are inhibitors of 356:. In those with HIV/AIDS, 5362: 5218:Bovine papular stomatitis 4848: 3048:American Family Physician 2673:British Journal of Cancer 1882:. Springer. p. 216. 1602:National Cancer Institute 1480:10.1038/s41572-019-0060-9 1324:10.1007/s40257-017-0270-4 1293:National Cancer Institute 938:, rapidly progressing to 634:KS lesions contain tumor 437:, back, face, mouth, and 49: 40: 5637:Gianotti–Crosti syndrome 5438:Merkel cell polyomavirus 5324:Laryngeal papillomatosis 4910:Herpes simplex keratitis 4754:Lymphangioleiomyomatosis 4595:African lymphadenopathic 4494:Tumours of blood vessels 4183:Thrombocytopenic purpura 3829:Dermatitis herpetiformis 3814:Acute contact dermatitis 3766:Pityriasis rubra pilaris 3691:Wiskott–Aldrich syndrome 3661:Lichen simplex chronicus 3541:Epidermal inclusion cyst 2401:(10th ed.). Mosby. 1198:Head & Face Medicine 538:or chest pain, or as an 485:infection in their mouth 267:42,000 (new cases, 2018) 5588:Boston exanthem disease 5258:Yaba monkey tumor virus 4940:Herpetiform esophagitis 4920:Neonatal herpes simplex 4448:Squamous-cell carcinoma 4443:Systemic histoplasmosis 3834:Porphyria cutanea tarda 3464:Squamous-cell carcinoma 2558:10.4103/0973-1482.80456 1688:10.1126/science.7997879 1165:opportunistic infection 760: 369:AIDS-defining illnesses 5012:Zoster-associated pain 4681:Universal angiomatosis 4647:Targeted hemosiderotic 4530:Endovascular papillary 4423:Cicatricial pemphigoid 4340:Acne keloidalis nuchae 4335:Folliculitis decalvans 2930:. Weinheim: Wiley-VCH. 909:calcineurin inhibitors 846:Classic Kaposi sarcoma 813:Bacillary angiomatosis 605: 516:intestinal obstruction 501:Gastrointestinal tract 486: 461:(obstruction of local 430: 422: 392:gastrointestinal tract 222:Differential diagnosis 18:Classic Kaposi sarcoma 5444:Merkel cell carcinoma 5367:Bovine papillomavirus 4325:Loose anagen syndrome 4252:Necrobiosis lipoidica 4188:Actinic/solar purpura 3862:Insect bite reactions 3651:Seborrheic dermatitis 3474:Merkel-cell carcinoma 3454:Molluscum contagiosum 3254:Journal of Immunology 1998:10.1378/chest.91.1.39 1760:. 2009. p. 1256. 1211:10.1186/1746-160X-6-7 600: 476: 428: 420: 327:organ transplantation 5786:Kaposi's sarcoma 5541:Alphavirus infection 5405:Erythema infectiosum 5182:Progressive vaccinia 5172:Generalized vaccinia 4997:Herpes zoster oticus 4520:Hemangioendothelioma 4148:Annulare centrifugum 3671:Glucagonoma syndrome 3469:Basal-cell carcinoma 3444:Seborrheic keratosis 3140:10.1128/JVI.01569-15 2685:10.1038/bjc.1998.717 2213:10.1056/NEJMoa055009 1849:(2 Suppl 3): 48–53. 1843:Seminars in Oncology 1752:"Kaposi's Sarcoma". 1076:improve this article 879:, mainly those from 798:Pneumocystis lesions 348:into the lesion, or 309:by a combination of 199:poor immune function 176:colored skin lesions 5042:Human herpesvirus 6 4393:Aphthous stomatitis 4330:Lichen planopilaris 4305:Androgenic alopecia 4111:Fixed drug eruption 3686:Pemphigus foliaceus 3586:Granular cell tumor 3128:Journal of Virology 2315:2013PLoSO...871530G 1796:2011PLoSO...618397J 1758:F. A. Davis Company 1680:1994Sci...266.1865C 1674:(5192): 1865–1869. 1013:(such as liposomal 319:Human herpesvirus 8 317:) and infection by 195:Human herpesvirus 8 5823:Vascular neoplasia 5744:External resources 5520:("German measles") 5334:Bowenoid papulosis 4905:Herpes gladiatorum 4703:Pyogenic granuloma 4568:Hemangiopericytoma 4413:Pemphigus vulgaris 4242:Granuloma annulare 4106:Carcinoid syndrome 3991:Tuberous sclerosis 3950:Coccidioidomycosis 3824:Bullous pemphigoid 3819:Pemphigus vulgaris 3751:Secondary syphilis 3641:Contact dermatitis 3375:2010-11-08 at the 1641:10.1007/BF01830024 1173:HIV/AIDS in Africa 1091:"Kaposi's sarcoma" 881:sub-Saharan Africa 818:Pyogenic granuloma 755:pyogenic granuloma 614:mesenchymal tissue 606: 540:incidental finding 487: 431: 423: 375:Signs and symptoms 311:immune suppression 231:pyogenic granuloma 5795: 5794: 5645: 5644: 5600: 5599: 5596: 5595: 5566:Coxsackie A virus 5546:Chikungunya fever 5454: 5453: 5410:Reticulocytopenia 5382: 5381: 5271: 5270: 5177:Eczema vaccinatum 5101: 5100: 5054:Exanthema subitum 5025: 5024: 5002:Ophthalmic zoster 4967:B virus infection 4935:Eczema herpeticum 4804: 4803: 4771:Lymphangiomatosis 4730:lymphangiosarcoma 4590:African cutaneous 4460: 4459: 4456: 4455: 4300:Telogen effluvium 4264: 4263: 4260: 4259: 4221: 4220: 4217: 4216: 4162: 4161: 4014: 4013: 3882:Lichen spinulosus 3877:Keratosis pilaris 3756:Mycosis fungoides 3656:Stasis dermatitis 3646:Atopic dermatitis 3609: 3608: 3484:Trichoepithelioma 3459:Actinic keratosis 2524:978-0-7216-2921-6 2408:978-0-8089-2433-3 2248:978-0-87969-571-2 1889:978-3-319-46352-0 1623:Kaposi M (1872). 1565:Ferri FF (2017). 1535:10.1159/000455971 1152: 1151: 1144: 1126: 1009:alpha, liposomal 659:endothelial cells 536:coughing up blood 522:Respiratory tract 463:lymphatic vessels 451:fungating lesions 396:respiratory tract 350:radiation therapy 279: 278: 254:radiation therapy 206:Diagnostic method 30:Medical condition 16:(Redirected from 5835: 5649: 5465: 5291: 5284: 5278:Papillomaviridae 5114: 5091:Kaposi's sarcoma 5059:Roseola vaccinia 4980: 4960: 4915:Herpetic sycosis 4900:Herpetic whitlow 4888: 4881: 4870: 4859: 4850: 4831: 4824: 4817: 4808: 4617:Hemangioblastoma 4585:Kaposi's sarcoma 4487: 4480: 4473: 4464: 4398:Oral candidiasis 4275: 4173: 4101:Erythema nodosum 4045: 4034: 4027: 3971:Tinea versicolor 3809:Bullous impetigo 3746:Pityriasis rosea 3681:Lichen sclerosus 3666:Darier's disease 3631: 3620: 3576:Kaposi's sarcoma 3422: 3406: 3399: 3392: 3383: 3357: 3356: 3346: 3314: 3308: 3307: 3305: 3303: 3294: 3286: 3280: 3279: 3269: 3245: 3239: 3238: 3209: 3203: 3202: 3192: 3168: 3162: 3161: 3151: 3119: 3113: 3112: 3102: 3070: 3064: 3063: 3043: 3037: 3036: 3000: 2994: 2993: 2953: 2947: 2946: 2938: 2932: 2931: 2920: 2914: 2913: 2898:Arizona Medicine 2893: 2887: 2886: 2876: 2852: 2846: 2845: 2835: 2811: 2805: 2804: 2786: 2762: 2756: 2755: 2737: 2713: 2707: 2706: 2696: 2664: 2655: 2654: 2626: 2620: 2619: 2601: 2577: 2571: 2570: 2560: 2539:Kumar P (2011). 2536: 2530: 2528: 2510: 2493: 2492: 2474: 2468: 2467: 2447: 2441: 2440: 2419: 2413: 2412: 2397:Rosai J (2011). 2394: 2388: 2387: 2377: 2353: 2347: 2346: 2336: 2326: 2294: 2288: 2287: 2259: 2253: 2252: 2232: 2226: 2225: 2215: 2191: 2185: 2184: 2163: 2157: 2156: 2146: 2122: 2116: 2115: 2105: 2073: 2067: 2066: 2056: 2024: 2018: 2017: 1981: 1975: 1974: 1950: 1944: 1943: 1941: 1940: 1931:. Archived from 1900: 1894: 1893: 1873: 1867: 1866: 1834: 1828: 1827: 1817: 1807: 1775: 1762: 1761: 1756:. Vol. 21. 1749: 1743: 1742: 1714: 1708: 1707: 1659: 1653: 1652: 1620: 1614: 1613: 1611: 1609: 1604:. 1 October 2015 1594: 1583: 1582: 1562: 1556: 1555: 1537: 1513: 1502: 1501: 1491: 1464:"Kaposi sarcoma" 1459: 1434: 1433: 1431: 1429: 1424: 1420:"Kaposi sarcoma" 1415: 1406: 1405: 1377: 1346: 1345: 1335: 1303: 1297: 1296: 1285: 1264: 1255: 1249: 1240: 1234: 1233: 1223: 1213: 1189: 1147: 1140: 1136: 1133: 1127: 1125: 1084: 1060: 1052: 979:immunodeficiency 952:mucous membranes 867:European peoples 859:Eastern European 725: 713: 701: 682: 667:immunoreactivity 354:biologic therapy 313:(such as due to 282:Kaposi's sarcoma 258:biologic therapy 235:melanocytic nevi 147: 146: 143: 142: 139: 136: 133: 130: 125: 124: 121: 118: 115: 112: 109: 106: 103: 94: 93: 90: 89: 86: 83: 80: 77: 74: 71: 68: 45: 33: 21: 5843: 5842: 5838: 5837: 5836: 5834: 5833: 5832: 5798: 5797: 5796: 5791: 5790: 5739: 5738: 5660: 5646: 5641: 5622:Lipschütz ulcer 5592: 5550: 5525: 5490: 5470:Paramyxoviridae 5450: 5421: 5378: 5358: 5287: 5267: 5237: 5213:Milker's nodule 5193: 5145:Monkeypox virus 5097: 5070: 5021: 4976: 4971: 4954: 4949: 4884: 4844: 4838:Skin infections 4835: 4805: 4800: 4775: 4712: 4600:AIDS-associated 4510:Hemangiosarcoma 4496: 4491: 4461: 4452: 4384: 4377: 4344: 4310:Alopecia areata 4288: 4270: 4256: 4213: 4192: 4168: 4158: 4115: 4074: 4060:Viral exanthems 4038: 4022: 4020: 4010: 3981:Pityriasis alba 3959: 3901: 3843: 3780: 3700: 3696:Zinc deficiency 3626: 3624: 3605: 3533: 3524: 3488: 3479:Nevus sebaceous 3413: 3410: 3377:Wayback Machine 3366: 3361: 3360: 3316: 3315: 3311: 3301: 3299: 3292: 3288: 3287: 3283: 3247: 3246: 3242: 3211: 3210: 3206: 3170: 3169: 3165: 3134:(21): 11144–9. 3121: 3120: 3116: 3085:(1): CD009826. 3072: 3071: 3067: 3054:(12): 1118–24. 3045: 3044: 3040: 3002: 3001: 2997: 2968:(8682): 123–8. 2955: 2954: 2950: 2940: 2939: 2935: 2922: 2921: 2917: 2895: 2894: 2890: 2867:(19): 1378–85. 2854: 2853: 2849: 2820:Transplantation 2813: 2812: 2808: 2764: 2763: 2759: 2715: 2714: 2710: 2666: 2665: 2658: 2628: 2627: 2623: 2592:(15): 2067–72. 2579: 2578: 2574: 2538: 2537: 2533: 2525: 2512: 2511: 2496: 2489: 2476: 2475: 2471: 2449: 2448: 2444: 2421: 2420: 2416: 2409: 2396: 2395: 2391: 2355: 2354: 2350: 2296: 2295: 2291: 2261: 2260: 2256: 2249: 2234: 2233: 2229: 2193: 2192: 2188: 2165: 2164: 2160: 2137:(19): 1369–77. 2124: 2123: 2119: 2075: 2074: 2070: 2026: 2025: 2021: 1983: 1982: 1978: 1952: 1951: 1947: 1938: 1936: 1902: 1901: 1897: 1890: 1875: 1874: 1870: 1836: 1835: 1831: 1777: 1776: 1765: 1751: 1750: 1746: 1716: 1715: 1711: 1661: 1660: 1656: 1622: 1621: 1617: 1607: 1605: 1596: 1595: 1586: 1579: 1564: 1563: 1559: 1515: 1514: 1505: 1461: 1460: 1437: 1427: 1425: 1422: 1417: 1416: 1409: 1379: 1378: 1349: 1305: 1304: 1300: 1295:. 16 June 2017. 1287: 1286: 1267: 1256: 1252: 1241: 1237: 1191: 1190: 1186: 1181: 1148: 1137: 1131: 1128: 1085: 1083: 1073: 1061: 1050: 1041: 975: 966: 877:African peoples 831: 803:Dermatophytosis 763: 736: 729: 726: 717: 714: 705: 702: 693: 683: 595: 583: 565:. KSHV encodes 556: 524: 503: 471: 449:with resulting 415: 377: 339:medical imaging 288:) is a type of 215:medical imaging 151: 127: 100: 96: 65: 61: 31: 28: 23: 22: 15: 12: 11: 5: 5841: 5839: 5831: 5830: 5825: 5820: 5815: 5810: 5800: 5799: 5793: 5792: 5789: 5788: 5777: 5760: 5748: 5747: 5745: 5741: 5740: 5737: 5736: 5725: 5714: 5703: 5692: 5677: 5661: 5656: 5655: 5653: 5652:Classification 5643: 5642: 5640: 5639: 5634: 5629: 5624: 5619: 5614: 5608: 5606: 5602: 5601: 5598: 5597: 5594: 5593: 5591: 5590: 5585: 5580: 5579: 5578: 5573: 5562: 5560: 5557:Picornaviridae 5552: 5551: 5549: 5548: 5543: 5537: 5535: 5527: 5526: 5524: 5523: 5522: 5521: 5515: 5502: 5500: 5492: 5491: 5489: 5488: 5487: 5486: 5475: 5473: 5462: 5456: 5455: 5452: 5451: 5449: 5448: 5447: 5446: 5433: 5431: 5428:Polyomaviridae 5423: 5422: 5420: 5419: 5418: 5417: 5412: 5407: 5399:Parvovirus B19 5394: 5392: 5384: 5383: 5380: 5379: 5377: 5376: 5375: 5374: 5372:Equine sarcoid 5363: 5360: 5359: 5357: 5356: 5351: 5349:Pigmented wart 5346: 5341: 5336: 5331: 5329:Butcher's wart 5326: 5321: 5320: 5319: 5309: 5307:Heck's disease 5304: 5294: 5292: 5281: 5273: 5272: 5269: 5268: 5266: 5265: 5260: 5255: 5245: 5243: 5239: 5238: 5236: 5235: 5230: 5225: 5220: 5215: 5205: 5203: 5195: 5194: 5192: 5191: 5186: 5185: 5184: 5179: 5174: 5169: 5162:Vaccinia virus 5159: 5154: 5153: 5152: 5142: 5141: 5140: 5135: 5124: 5122: 5111: 5103: 5102: 5099: 5098: 5096: 5095: 5094: 5093: 5082: 5080: 5072: 5071: 5069: 5068: 5063: 5062: 5061: 5056: 5037: 5035: 5027: 5026: 5023: 5022: 5020: 5019: 5014: 5009: 5004: 4999: 4994: 4989: 4983: 4981: 4973: 4972: 4970: 4969: 4963: 4961: 4951: 4950: 4948: 4947: 4942: 4937: 4932: 4927: 4925:Genital herpes 4922: 4917: 4912: 4907: 4902: 4897: 4895:Herpes simplex 4891: 4889: 4878: 4867: 4856: 4846: 4845: 4836: 4834: 4833: 4826: 4819: 4811: 4802: 4801: 4799: 4798: 4793: 4783: 4781: 4777: 4776: 4774: 4773: 4768: 4763: 4761:Cystic hygroma 4758: 4757: 4756: 4744: 4743: 4742: 4737: 4722: 4720: 4714: 4713: 4711: 4710: 4705: 4700: 4699: 4698: 4693: 4683: 4678: 4677: 4676: 4671: 4666: 4661: 4651: 4650: 4649: 4644: 4639: 4634: 4629: 4619: 4614: 4613: 4612: 4607: 4602: 4597: 4592: 4582: 4577: 4576: 4575: 4565: 4560: 4559: 4558: 4553: 4547: 4542: 4537: 4532: 4527: 4517: 4512: 4506: 4504: 4498: 4497: 4492: 4490: 4489: 4482: 4475: 4467: 4458: 4457: 4454: 4453: 4451: 4450: 4445: 4440: 4435: 4433:Coxsackievirus 4430: 4425: 4420: 4415: 4410: 4405: 4400: 4395: 4389: 4387: 4379: 4378: 4376: 4375: 4370: 4365: 4360: 4354: 4352: 4346: 4345: 4343: 4342: 4337: 4332: 4327: 4322: 4317: 4312: 4307: 4302: 4296: 4294: 4290: 4289: 4287: 4286: 4283: 4281: 4272: 4266: 4265: 4262: 4261: 4258: 4257: 4255: 4254: 4249: 4244: 4239: 4229: 4227: 4223: 4222: 4219: 4218: 4215: 4214: 4212: 4211: 4206: 4200: 4198: 4194: 4193: 4191: 4190: 4185: 4179: 4177: 4170: 4164: 4163: 4160: 4159: 4157: 4156: 4150: 4145: 4143:Gyratum repens 4140: 4135: 4129: 4123: 4121: 4117: 4116: 4114: 4113: 4108: 4103: 4098: 4093: 4088: 4082: 4080: 4076: 4075: 4073: 4072: 4067: 4065:Toxic erythema 4062: 4057: 4055:Drug eruptions 4051: 4049: 4042: 4031: 4024: 4016: 4015: 4012: 4011: 4009: 4008: 4003: 3998: 3993: 3988: 3983: 3978: 3973: 3967: 3965: 3961: 3960: 3958: 3957: 3952: 3947: 3942: 3937: 3932: 3927: 3922: 3917: 3911: 3909: 3903: 3902: 3900: 3899: 3894: 3892:Lichen nitidus 3889: 3884: 3879: 3874: 3869: 3864: 3859: 3853: 3851: 3845: 3844: 3842: 3841: 3836: 3831: 3826: 3821: 3816: 3811: 3806: 3801: 3796: 3794:Herpes simplex 3790: 3788: 3782: 3781: 3779: 3778: 3773: 3768: 3763: 3758: 3753: 3748: 3743: 3737: 3732: 3727: 3722: 3716: 3710: 3708: 3702: 3701: 3699: 3698: 3693: 3688: 3683: 3678: 3673: 3668: 3663: 3658: 3653: 3648: 3643: 3637: 3635: 3628: 3617: 3611: 3610: 3607: 3606: 3604: 3603: 3598: 3593: 3588: 3583: 3578: 3573: 3568: 3563: 3558: 3553: 3548: 3543: 3537: 3535: 3526: 3525: 3523: 3522: 3517: 3512: 3507: 3502: 3496: 3494: 3490: 3489: 3487: 3486: 3481: 3476: 3471: 3466: 3461: 3456: 3451: 3446: 3441: 3436: 3430: 3428: 3419: 3415: 3414: 3411: 3409: 3408: 3401: 3394: 3386: 3380: 3379: 3365: 3364:External links 3362: 3359: 3358: 3329:(12): 1011–4. 3309: 3281: 3240: 3221:(6): 1876–83. 3204: 3183:(1): 153–155. 3163: 3114: 3065: 3038: 2995: 2948: 2933: 2915: 2888: 2847: 2806: 2777:(14): 1921–5. 2757: 2728:(14): 1921–5. 2708: 2679:(11): 1521–8. 2656: 2637:(5): 498–500. 2621: 2572: 2531: 2523: 2494: 2487: 2469: 2458:(2): 123–127. 2442: 2431:(2): 243–251. 2414: 2407: 2389: 2368:(2): 294–300. 2348: 2289: 2254: 2247: 2227: 2206:(13): 1331–8. 2186: 2158: 2117: 2088:(6): 423–436. 2068: 2039:(3): 439–464. 2019: 1976: 1945: 1895: 1888: 1868: 1829: 1763: 1744: 1709: 1654: 1635:(2): 265–273. 1615: 1584: 1577: 1557: 1503: 1435: 1407: 1347: 1318:(4): 529–539. 1298: 1265: 1250: 1235: 1183: 1182: 1180: 1177: 1150: 1149: 1064: 1062: 1055: 1049: 1046: 1040: 1037: 1011:anthracyclines 974: 971: 965: 962: 961: 960: 925: 919:function) for 902: 901: 900: 894: 870: 855:Arab countries 830: 829:Classification 827: 826: 825: 820: 815: 810: 805: 800: 795: 790: 788:Histoplasmosis 785: 783:Cryptococcosis 780: 775: 762: 759: 735: 732: 731: 730: 727: 720: 718: 715: 708: 706: 703: 696: 694: 684: 677: 661:, probably of 594: 591: 582: 579: 555: 552: 523: 520: 502: 499: 470: 467: 447:skin breakdown 414: 411: 376: 373: 277: 276: 273: 269: 268: 265: 261: 260: 246: 242: 241: 224: 218: 217: 208: 202: 201: 192: 186: 185: 182: 178: 177: 171: 165: 164: 159: 153: 152: 150: 149: 58: 56: 52: 51: 47: 46: 38: 37: 29: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 5840: 5829: 5826: 5824: 5821: 5819: 5816: 5814: 5811: 5809: 5806: 5805: 5803: 5787: 5783: 5782: 5778: 5776: 5773: 5770: 5766: 5765: 5761: 5759: 5755: 5754: 5750: 5749: 5746: 5742: 5735: 5731: 5730: 5726: 5724: 5720: 5719: 5715: 5713: 5709: 5708: 5704: 5702: 5698: 5697: 5693: 5691: 5687: 5686: 5682: 5678: 5676: 5672: 5671: 5667: 5663: 5662: 5659: 5654: 5650: 5638: 5635: 5633: 5630: 5628: 5625: 5623: 5620: 5618: 5615: 5613: 5610: 5609: 5607: 5603: 5589: 5586: 5584: 5581: 5577: 5574: 5572: 5569: 5568: 5567: 5564: 5563: 5561: 5559: 5558: 5553: 5547: 5544: 5542: 5539: 5538: 5536: 5534: 5533: 5528: 5519: 5516: 5514: 5511: 5510: 5509: 5508: 5507:Rubella virus 5504: 5503: 5501: 5499: 5498: 5497:Matonaviridae 5493: 5485: 5482: 5481: 5480: 5477: 5476: 5474: 5472: 5471: 5466: 5463: 5461: 5457: 5445: 5442: 5441: 5440: 5439: 5435: 5434: 5432: 5430: 5429: 5424: 5416: 5413: 5411: 5408: 5406: 5403: 5402: 5401: 5400: 5396: 5395: 5393: 5391: 5390: 5385: 5373: 5370: 5369: 5368: 5365: 5364: 5361: 5355: 5352: 5350: 5347: 5345: 5344:Verruca plana 5342: 5340: 5337: 5335: 5332: 5330: 5327: 5325: 5322: 5318: 5315: 5314: 5313: 5310: 5308: 5305: 5303: 5299: 5296: 5295: 5293: 5290: 5285: 5282: 5280: 5279: 5274: 5264: 5261: 5259: 5256: 5254: 5250: 5247: 5246: 5244: 5240: 5234: 5231: 5229: 5226: 5224: 5221: 5219: 5216: 5214: 5210: 5207: 5206: 5204: 5202: 5201: 5196: 5190: 5187: 5183: 5180: 5178: 5175: 5173: 5170: 5168: 5165: 5164: 5163: 5160: 5158: 5155: 5151: 5148: 5147: 5146: 5143: 5139: 5136: 5134: 5131: 5130: 5129: 5126: 5125: 5123: 5121: 5120: 5115: 5112: 5110: 5109: 5104: 5092: 5089: 5088: 5087: 5084: 5083: 5081: 5079: 5078: 5073: 5067: 5064: 5060: 5057: 5055: 5052: 5051: 5050: 5049: 5044: 5043: 5039: 5038: 5036: 5034: 5033: 5028: 5018: 5015: 5013: 5010: 5008: 5005: 5003: 5000: 4998: 4995: 4993: 4992:Herpes zoster 4990: 4988: 4985: 4984: 4982: 4979: 4974: 4968: 4965: 4964: 4962: 4959: 4958: 4952: 4946: 4943: 4941: 4938: 4936: 4933: 4931: 4928: 4926: 4923: 4921: 4918: 4916: 4913: 4911: 4908: 4906: 4903: 4901: 4898: 4896: 4893: 4892: 4890: 4887: 4882: 4879: 4877: 4876: 4871: 4868: 4866: 4865: 4864:Herpesviridae 4860: 4857: 4855: 4851: 4847: 4843: 4839: 4832: 4827: 4825: 4820: 4818: 4813: 4812: 4809: 4797: 4794: 4792: 4788: 4785: 4784: 4782: 4778: 4772: 4769: 4767: 4764: 4762: 4759: 4755: 4752: 4751: 4750: 4749: 4745: 4741: 4738: 4736: 4733: 4732: 4731: 4727: 4724: 4723: 4721: 4719: 4715: 4709: 4706: 4704: 4701: 4697: 4694: 4692: 4689: 4688: 4687: 4686:Angiokeratoma 4684: 4682: 4679: 4675: 4672: 4670: 4667: 4665: 4662: 4660: 4657: 4656: 4655: 4652: 4648: 4645: 4643: 4640: 4638: 4635: 4633: 4630: 4628: 4625: 4624: 4623: 4620: 4618: 4615: 4611: 4608: 4606: 4603: 4601: 4598: 4596: 4593: 4591: 4588: 4587: 4586: 4583: 4581: 4578: 4574: 4571: 4570: 4569: 4566: 4564: 4561: 4557: 4554: 4551: 4548: 4546: 4543: 4541: 4538: 4536: 4533: 4531: 4528: 4526: 4523: 4522: 4521: 4518: 4516: 4513: 4511: 4508: 4507: 4505: 4503: 4499: 4495: 4488: 4483: 4481: 4476: 4474: 4469: 4468: 4465: 4449: 4446: 4444: 4441: 4439: 4436: 4434: 4431: 4429: 4426: 4424: 4421: 4419: 4416: 4414: 4411: 4409: 4406: 4404: 4403:Lichen planus 4401: 4399: 4396: 4394: 4391: 4390: 4388: 4386: 4380: 4374: 4371: 4369: 4366: 4364: 4361: 4359: 4358:Onychomycosis 4356: 4355: 4353: 4351: 4347: 4341: 4338: 4336: 4333: 4331: 4328: 4326: 4323: 4321: 4320:Tinea capitis 4318: 4316: 4313: 4311: 4308: 4306: 4303: 4301: 4298: 4297: 4295: 4291: 4285: 4284: 4282: 4280: 4276: 4273: 4269:Miscellaneous 4267: 4253: 4250: 4248: 4245: 4243: 4240: 4238: 4234: 4231: 4230: 4228: 4224: 4210: 4207: 4205: 4202: 4201: 4199: 4195: 4189: 4186: 4184: 4181: 4180: 4178: 4174: 4171: 4167:Nonblanchable 4165: 4154: 4151: 4149: 4146: 4144: 4141: 4139: 4136: 4134: 4130: 4128: 4125: 4124: 4122: 4118: 4112: 4109: 4107: 4104: 4102: 4099: 4097: 4094: 4092: 4089: 4087: 4084: 4083: 4081: 4077: 4071: 4068: 4066: 4063: 4061: 4058: 4056: 4053: 4052: 4050: 4046: 4043: 4041: 4035: 4032: 4028: 4025: 4017: 4007: 4004: 4002: 3999: 3997: 3994: 3992: 3989: 3987: 3984: 3982: 3979: 3977: 3974: 3972: 3969: 3968: 3966: 3964:Hypopigmented 3962: 3956: 3953: 3951: 3948: 3946: 3943: 3941: 3938: 3936: 3933: 3931: 3928: 3926: 3923: 3921: 3918: 3916: 3915:Acne vulgaris 3913: 3912: 3910: 3908: 3904: 3898: 3895: 3893: 3890: 3888: 3885: 3883: 3880: 3878: 3875: 3873: 3870: 3868: 3867:Lichen planus 3865: 3863: 3860: 3858: 3855: 3854: 3852: 3850: 3846: 3840: 3837: 3835: 3832: 3830: 3827: 3825: 3822: 3820: 3817: 3815: 3812: 3810: 3807: 3805: 3802: 3800: 3799:Herpes zoster 3797: 3795: 3792: 3791: 3789: 3787: 3783: 3777: 3774: 3772: 3771:Parapsoriasis 3769: 3767: 3764: 3762: 3759: 3757: 3754: 3752: 3749: 3747: 3744: 3741: 3738: 3736: 3733: 3731: 3728: 3726: 3723: 3721: 3717: 3715: 3712: 3711: 3709: 3707: 3703: 3697: 3694: 3692: 3689: 3687: 3684: 3682: 3679: 3677: 3674: 3672: 3669: 3667: 3664: 3662: 3659: 3657: 3654: 3652: 3649: 3647: 3644: 3642: 3639: 3638: 3636: 3632: 3629: 3621: 3618: 3616: 3612: 3602: 3599: 3597: 3594: 3592: 3589: 3587: 3584: 3582: 3579: 3577: 3574: 3572: 3569: 3567: 3564: 3562: 3559: 3557: 3554: 3552: 3549: 3547: 3544: 3542: 3539: 3538: 3536: 3531: 3527: 3521: 3518: 3516: 3513: 3511: 3508: 3506: 3503: 3501: 3498: 3497: 3495: 3491: 3485: 3482: 3480: 3477: 3475: 3472: 3470: 3467: 3465: 3462: 3460: 3457: 3455: 3452: 3450: 3447: 3445: 3442: 3440: 3437: 3435: 3432: 3431: 3429: 3427: 3423: 3420: 3416: 3407: 3402: 3400: 3395: 3393: 3388: 3387: 3384: 3378: 3374: 3371: 3368: 3367: 3363: 3354: 3350: 3345: 3340: 3336: 3332: 3328: 3324: 3320: 3313: 3310: 3298: 3291: 3285: 3282: 3277: 3273: 3268: 3263: 3260:(1): 509–17. 3259: 3255: 3251: 3244: 3241: 3236: 3232: 3228: 3224: 3220: 3216: 3208: 3205: 3200: 3196: 3191: 3186: 3182: 3178: 3174: 3167: 3164: 3159: 3155: 3150: 3145: 3141: 3137: 3133: 3129: 3125: 3118: 3115: 3110: 3106: 3101: 3096: 3092: 3088: 3084: 3080: 3076: 3069: 3066: 3061: 3057: 3053: 3049: 3042: 3039: 3034: 3030: 3026: 3022: 3018: 3014: 3011:(9): 839–46. 3010: 3006: 2999: 2996: 2991: 2987: 2983: 2979: 2975: 2971: 2967: 2963: 2959: 2952: 2949: 2944: 2937: 2934: 2929: 2925: 2919: 2916: 2911: 2907: 2904:(12): 902–4. 2903: 2899: 2892: 2889: 2884: 2880: 2875: 2870: 2866: 2862: 2858: 2851: 2848: 2843: 2839: 2834: 2829: 2825: 2821: 2817: 2810: 2807: 2802: 2798: 2794: 2790: 2785: 2780: 2776: 2772: 2768: 2761: 2758: 2753: 2749: 2745: 2741: 2736: 2731: 2727: 2723: 2719: 2712: 2709: 2704: 2700: 2695: 2690: 2686: 2682: 2678: 2674: 2670: 2663: 2661: 2657: 2652: 2648: 2644: 2640: 2636: 2632: 2625: 2622: 2617: 2613: 2609: 2605: 2600: 2595: 2591: 2587: 2583: 2576: 2573: 2568: 2564: 2559: 2554: 2550: 2546: 2542: 2535: 2532: 2526: 2520: 2516: 2509: 2507: 2505: 2503: 2501: 2499: 2495: 2490: 2488:9781118441190 2484: 2480: 2473: 2470: 2465: 2461: 2457: 2453: 2446: 2443: 2438: 2434: 2430: 2426: 2418: 2415: 2410: 2404: 2400: 2393: 2390: 2385: 2381: 2376: 2371: 2367: 2363: 2359: 2352: 2349: 2344: 2340: 2335: 2330: 2325: 2320: 2316: 2312: 2309:(8): e71530. 2308: 2304: 2300: 2293: 2290: 2285: 2281: 2277: 2273: 2270:(2): 107–24. 2269: 2265: 2258: 2255: 2250: 2244: 2240: 2239: 2231: 2228: 2223: 2219: 2214: 2209: 2205: 2201: 2197: 2190: 2187: 2182: 2178: 2175:(7): 2826–9. 2174: 2170: 2162: 2159: 2154: 2150: 2145: 2140: 2136: 2132: 2128: 2121: 2118: 2113: 2109: 2104: 2099: 2095: 2091: 2087: 2083: 2079: 2072: 2069: 2064: 2060: 2055: 2050: 2046: 2042: 2038: 2034: 2030: 2023: 2020: 2015: 2011: 2007: 2003: 1999: 1995: 1991: 1987: 1980: 1977: 1972: 1968: 1964: 1960: 1956: 1949: 1946: 1935:on 2007-09-29 1934: 1930: 1926: 1922: 1918: 1915:(11): 78–84. 1914: 1910: 1906: 1899: 1896: 1891: 1885: 1881: 1880: 1872: 1869: 1864: 1860: 1856: 1852: 1848: 1844: 1840: 1833: 1830: 1825: 1821: 1816: 1811: 1806: 1801: 1797: 1793: 1790:(4): e18397. 1789: 1785: 1781: 1774: 1772: 1770: 1768: 1764: 1759: 1755: 1748: 1745: 1740: 1736: 1732: 1728: 1725:(5): 1023–9. 1724: 1720: 1713: 1710: 1705: 1701: 1697: 1693: 1689: 1685: 1681: 1677: 1673: 1669: 1665: 1658: 1655: 1650: 1646: 1642: 1638: 1634: 1630: 1626: 1619: 1616: 1603: 1599: 1593: 1591: 1589: 1585: 1580: 1578:9780323529570 1574: 1570: 1569: 1561: 1558: 1553: 1549: 1545: 1541: 1536: 1531: 1527: 1523: 1519: 1512: 1510: 1508: 1504: 1499: 1495: 1490: 1485: 1481: 1477: 1473: 1469: 1465: 1458: 1456: 1454: 1452: 1450: 1448: 1446: 1444: 1442: 1440: 1436: 1421: 1414: 1412: 1408: 1403: 1399: 1395: 1391: 1387: 1383: 1376: 1374: 1372: 1370: 1368: 1366: 1364: 1362: 1360: 1358: 1356: 1354: 1352: 1348: 1343: 1339: 1334: 1329: 1325: 1321: 1317: 1313: 1309: 1302: 1299: 1294: 1290: 1284: 1282: 1280: 1278: 1276: 1274: 1272: 1270: 1266: 1263: 1259: 1254: 1251: 1248: 1244: 1239: 1236: 1231: 1227: 1222: 1217: 1212: 1207: 1203: 1199: 1195: 1188: 1185: 1178: 1176: 1174: 1170: 1169:immune system 1166: 1161: 1159: 1158: 1146: 1143: 1135: 1132:November 2020 1124: 1121: 1117: 1114: 1110: 1107: 1103: 1100: 1096: 1093: –  1092: 1088: 1087:Find sources: 1081: 1077: 1071: 1070: 1065:This section 1063: 1059: 1054: 1053: 1047: 1045: 1038: 1036: 1034: 1030: 1028: 1024: 1020: 1016: 1012: 1008: 1004: 1000: 999:beta-blockers 996: 992: 987: 985: 980: 972: 970: 963: 957: 953: 949: 945: 941: 937: 933: 929: 926: 922: 918: 914: 913:ciclosporines 910: 906: 903: 898: 895: 892: 889: 888: 886: 885:HIV infection 882: 878: 874: 871: 868: 864: 860: 856: 852: 851:Mediterranean 847: 844: 843: 842: 840: 836: 835:Moritz Kaposi 828: 824: 821: 819: 816: 814: 811: 809: 806: 804: 801: 799: 796: 794: 793:Leishmaniasis 791: 789: 786: 784: 781: 779: 776: 773: 770: 769: 768: 767: 758: 756: 752: 747: 745: 741: 733: 724: 719: 712: 707: 700: 695: 691: 690:H&E stain 687: 681: 676: 674: 672: 668: 664: 660: 655: 653: 649: 645: 641: 640:spindle cells 637: 632: 630: 627: 623: 619: 615: 611: 603: 599: 592: 590: 587: 580: 578: 576: 575:circular RNAs 572: 568: 564: 560: 553: 551: 549: 545: 541: 537: 533: 529: 521: 519: 517: 513: 512:malabsorption 509: 500: 498: 496: 492: 484: 480: 475: 468: 466: 464: 460: 456: 452: 448: 444: 440: 436: 427: 419: 412: 410: 407: 405: 401: 397: 393: 388: 386: 382: 374: 372: 370: 366: 365:Moritz Kaposi 361: 359: 355: 351: 347: 342: 340: 336: 335:tissue biopsy 332: 328: 322: 320: 316: 312: 307: 303: 299: 295: 291: 287: 283: 275:20,000 (2018) 274: 270: 266: 262: 259: 255: 251: 247: 243: 240: 236: 232: 228: 225: 223: 219: 216: 212: 211:Tissue biopsy 209: 207: 203: 200: 196: 193: 191: 187: 183: 179: 175: 172: 170: 166: 163: 160: 158: 154: 145: 92: 60: 59: 57: 55:Pronunciation 53: 48: 44: 39: 34: 19: 5828:Rare cancers 5779: 5762: 5751: 5727: 5716: 5705: 5694: 5679: 5664: 5555: 5530: 5505: 5495: 5468: 5436: 5426: 5397: 5389:Parvoviridae 5387: 5312:Genital wart 5302:plantar wart 5276: 5249:Yatapoxvirus 5223:Pseudocowpox 5209:Farmyard pox 5198: 5117: 5106: 5090: 5075: 5048:Roseolovirus 5046: 5040: 5030: 4955: 4873: 4862: 4796:Angiofibroma 4791:angiosarcoma 4746: 4726:Lymphangioma 4642:Microvenular 4584: 4556:Spindle cell 4502:Blood vessel 4373:Ingrown nail 3945:Dermatophyte 3940:Gonococcemia 3925:Folliculitis 3575: 3566:Neurofibroma 3534:subcutaneous 3326: 3322: 3312: 3300:. Retrieved 3296: 3284: 3257: 3253: 3243: 3218: 3214: 3207: 3180: 3176: 3166: 3131: 3127: 3117: 3082: 3078: 3068: 3051: 3047: 3041: 3008: 3004: 2998: 2965: 2961: 2951: 2942: 2936: 2927: 2918: 2901: 2897: 2891: 2864: 2860: 2850: 2826:(4): 583–5. 2823: 2819: 2809: 2774: 2770: 2760: 2725: 2721: 2711: 2676: 2672: 2634: 2630: 2624: 2589: 2585: 2575: 2548: 2544: 2534: 2514: 2478: 2472: 2455: 2451: 2445: 2428: 2424: 2417: 2398: 2392: 2365: 2361: 2351: 2306: 2302: 2292: 2267: 2263: 2257: 2238:Retroviruses 2237: 2230: 2203: 2199: 2189: 2172: 2168: 2161: 2134: 2130: 2120: 2085: 2081: 2071: 2036: 2032: 2022: 1992:(1): 39–43. 1989: 1985: 1979: 1965:(6): 715–8. 1962: 1958: 1948: 1937:. Retrieved 1933:the original 1912: 1908: 1898: 1878: 1871: 1846: 1842: 1832: 1787: 1783: 1753: 1747: 1722: 1718: 1712: 1671: 1667: 1657: 1632: 1628: 1618: 1606:. Retrieved 1601: 1567: 1560: 1528:(3): 94–98. 1525: 1521: 1471: 1467: 1426:. Retrieved 1385: 1381: 1315: 1311: 1301: 1292: 1257: 1253: 1242: 1238: 1201: 1197: 1187: 1162: 1157:Philadelphia 1155: 1153: 1138: 1129: 1119: 1112: 1105: 1098: 1086: 1074:Please help 1069:verification 1066: 1042: 1039:Epidemiology 1033:Alitretinoin 1031: 1019:daunorubicin 995:chemotherapy 988: 976: 967: 927: 904: 896: 890: 872: 863:Israeli Jews 845: 832: 778:Histiocytoma 765: 764: 748: 737: 663:lymph vessel 656: 648:Inflammation 639: 633: 618:histogenesis 607: 588: 584: 581:Transmission 557: 548:bronchoscopy 525: 504: 488: 455:inflammation 432: 408: 389: 378: 362: 346:chemotherapy 343: 323: 285: 281: 280: 250:chemotherapy 190:Risk factors 5753:MedlinePlus 5532:Togaviridae 4696:Angiolipoma 4664:Seriginosum 4637:Glomeruloid 4580:Venous lake 4535:Epithelioid 4428:Herpesvirus 4408:Leukoplakia 4233:Scleroderma 4120:Specialized 4048:Generalized 4023:involvement 3935:Candidiasis 3627:involvement 3601:Myxoid cyst 3449:Acrochordon 2551:(1): 92–4. 2167:patients". 1608:18 December 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Index

Classic Kaposi sarcoma

/kæˈpsiz/
/ˈkɑːpəsiz,ˈkæpə-/
Specialty
Oncology
Symptoms
Purple
Risk factors
Human herpesvirus 8
poor immune function
Diagnostic method
Tissue biopsy
medical imaging
Differential diagnosis
Blue rubber bleb nevus syndrome
pyogenic granuloma
melanocytic nevi
melanoma
chemotherapy
radiation therapy
biologic therapy
cancer
skin
lymph nodes
organs
purple
immune suppression
HIV/AIDS
Human herpesvirus 8

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