901:
472:"Cloning and characterization of 1-deoxy-D-xylulose 5-phosphate synthase from Streptomyces sp. Strain CL190, which uses both the mevalonate and nonmevalonate pathways for isopentenyl diphosphate biosynthesis"
978:
968:
933:
419:"Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol"
534:
973:
293:
983:
988:
197:
216:
926:
1043:
527:
919:
520:
1067:
620:
209:
1036:
326:
136:
776:
160:
891:
315:
404:
400:
1072:
761:
1029:
877:
864:
851:
838:
825:
812:
799:
564:
771:
725:
668:
555:
380:
307:
246:
154:
47:
673:
141:
946:
257:
278:
694:
613:
572:
221:
766:
129:
64:
963:
430:
730:
322:
59:
157:
663:
392:
81:
1062:
911:
501:
458:
396:
265:
148:
1013:
709:
704:
678:
606:
491:
483:
448:
438:
756:
740:
653:
356:
117:
512:
434:
93:
905:
794:
735:
334:
192:
52:
172:
1056:
699:
658:
582:
577:
496:
471:
453:
418:
167:
958:
648:
587:
487:
1009:
872:
807:
643:
543:
344:
176:
900:
942:
234:
443:
846:
820:
261:
17:
505:
462:
547:
348:
311:
249:
124:
105:
859:
629:
551:
365:-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating)
352:
253:
204:
100:
88:
76:
833:
112:
915:
602:
516:
355:
groups (transaldolases and transketolases, respectively). The
598:
979:
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
969:
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
282:
1017:
974:
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
889:
281:
984:
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
373:-xylulose-5-phosphate pyruvate-lyase (carboxylating)
785:
749:
718:
687:
636:
563:
215:
203:
191:
186:
166:
147:
135:
123:
111:
99:
87:
75:
70:
58:
46:
41:
32:
989:4-hydroxy-3-methylbut-2-enyl diphosphate reductase
470:Kuzuyama T, Takagi M, Takahashi S, Seto H (2000).
287:
395:have been solved for this class of enzymes, with
417:SV, Begley TP; Bringer-Meyer S; Sahm H (1997).
1037:
927:
614:
528:
8:
1044:
1030:
934:
920:
912:
621:
607:
599:
535:
521:
513:
183:
495:
452:
442:
280:
896:
29:
343:This enzyme belongs to the family of
7:
1005:
1003:
367:. Other names in common use include
288:{\displaystyle \rightleftharpoons }
1016:. You can help Knowledge (XXG) by
347:, specifically those transferring
25:
899:
379:. This enzyme participates in
243:-xylulose-5-phosphate synthase
37:-xylulose-5-phosphate synthase
1:
488:10.1128/JB.182.4.891-897.2000
423:Proc. Natl. Acad. Sci. U.S.A
275:-glyceraldehyde 3-phosphate
319:-glyceraldehyde 3-phosphate
1089:
1068:Enzymes of known structure
1002:
299:-xylulose 5-phosphate + CO
954:
777:Michaelis–Menten kinetics
182:
669:Diffusion-limited enzyme
444:10.1073/pnas.94.24.12857
381:biosynthesis of steroids
359:of this enzyme class is
947:non-mevalonate pathway
289:
258:non-mevalonate pathway
762:Eadie–Hofstee diagram
695:Allosteric regulation
573:Acetolactate synthase
391:As of late 2007, two
331:-xylulose 5-phosphate
290:
964:DXP reductoisomerase
772:Lineweaver–Burk plot
279:
435:1997PNAS...9412857S
310:of this enzyme are
731:Enzyme superfamily
664:Enzyme promiscuity
387:Structural studies
321:, whereas its two
285:
1073:Transferase stubs
1025:
1024:
997:
996:
887:
886:
596:
595:
266:chemical reaction
231:
230:
227:
226:
130:metabolic pathway
16:(Redirected from
1080:
1046:
1039:
1032:
1004:
936:
929:
922:
913:
904:
903:
895:
767:Hanes–Woolf plot
710:Enzyme activator
705:Enzyme inhibitor
679:Enzyme catalysis
623:
616:
609:
600:
537:
530:
523:
514:
509:
499:
466:
456:
446:
429:(24): 12857–62.
399:accession codes
372:
364:
330:
318:
298:
294:
292:
291:
286:
274:
242:
184:
36:
30:
27:Class of enzymes
21:
1088:
1087:
1083:
1082:
1081:
1079:
1078:
1077:
1053:
1052:
1051:
1050:
1000:
998:
993:
950:
940:
910:
898:
890:
888:
883:
795:Oxidoreductases
781:
757:Enzyme kinetics
745:
741:List of enzymes
714:
683:
654:Catalytic triad
632:
627:
597:
592:
559:
541:
469:
416:
413:
389:
370:
362:
357:systematic name
338:
328:
316:
302:
296:
277:
276:
272:
240:
34:
28:
23:
22:
15:
12:
11:
5:
1086:
1084:
1076:
1075:
1070:
1065:
1055:
1054:
1049:
1048:
1041:
1034:
1026:
1023:
1022:
995:
994:
992:
991:
986:
981:
976:
971:
966:
961:
955:
952:
951:
941:
939:
938:
931:
924:
916:
909:
908:
885:
884:
882:
881:
868:
855:
842:
829:
816:
803:
789:
787:
783:
782:
780:
779:
774:
769:
764:
759:
753:
751:
747:
746:
744:
743:
738:
733:
728:
722:
720:
719:Classification
716:
715:
713:
712:
707:
702:
697:
691:
689:
685:
684:
682:
681:
676:
671:
666:
661:
656:
651:
646:
640:
638:
634:
633:
628:
626:
625:
618:
611:
603:
594:
593:
591:
590:
585:
580:
575:
569:
567:
561:
560:
542:
540:
539:
532:
525:
517:
511:
510:
467:
412:
409:
388:
385:
336:
306:Thus, the two
304:
303:
300:
284:
229:
228:
225:
224:
219:
213:
212:
207:
201:
200:
195:
189:
188:
180:
179:
170:
164:
163:
152:
145:
144:
139:
133:
132:
127:
121:
120:
115:
109:
108:
103:
97:
96:
91:
85:
84:
79:
73:
72:
68:
67:
62:
56:
55:
50:
44:
43:
39:
38:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
1085:
1074:
1071:
1069:
1066:
1064:
1061:
1060:
1058:
1047:
1042:
1040:
1035:
1033:
1028:
1027:
1021:
1019:
1015:
1012:article is a
1011:
1006:
1001:
990:
987:
985:
982:
980:
977:
975:
972:
970:
967:
965:
962:
960:
957:
956:
953:
948:
944:
937:
932:
930:
925:
923:
918:
917:
914:
907:
902:
897:
893:
879:
875:
874:
869:
866:
862:
861:
856:
853:
849:
848:
843:
840:
836:
835:
830:
827:
823:
822:
817:
814:
810:
809:
804:
801:
797:
796:
791:
790:
788:
784:
778:
775:
773:
770:
768:
765:
763:
760:
758:
755:
754:
752:
748:
742:
739:
737:
736:Enzyme family
734:
732:
729:
727:
724:
723:
721:
717:
711:
708:
706:
703:
701:
700:Cooperativity
698:
696:
693:
692:
690:
686:
680:
677:
675:
672:
670:
667:
665:
662:
660:
659:Oxyanion hole
657:
655:
652:
650:
647:
645:
642:
641:
639:
635:
631:
624:
619:
617:
612:
610:
605:
604:
601:
589:
586:
584:
583:Transketolase
581:
579:
578:Transaldolase
576:
574:
571:
570:
568:
566:
562:
557:
553:
549:
545:
538:
533:
531:
526:
524:
519:
518:
515:
507:
503:
498:
493:
489:
485:
481:
477:
473:
468:
464:
460:
455:
450:
445:
440:
436:
432:
428:
424:
420:
415:
414:
410:
408:
406:
402:
398:
394:
386:
384:
382:
378:
374:
366:
358:
354:
350:
346:
341:
339:
332:
324:
320:
313:
309:
270:
269:
268:
267:
263:
259:
255:
251:
248:
244:
236:
223:
220:
218:
214:
211:
208:
206:
202:
199:
196:
194:
190:
185:
181:
178:
174:
171:
169:
168:Gene Ontology
165:
162:
159:
156:
153:
150:
146:
143:
140:
138:
134:
131:
128:
126:
122:
119:
116:
114:
110:
107:
106:NiceZyme view
104:
102:
98:
95:
92:
90:
86:
83:
80:
78:
74:
69:
66:
63:
61:
57:
54:
51:
49:
45:
40:
31:
19:
1018:expanding it
1007:
999:
959:DXP synthase
873:Translocases
870:
857:
844:
831:
818:
808:Transferases
805:
792:
649:Binding site
588:DXP synthase
544:Transferases
482:(4): 891–7.
479:
476:J. Bacteriol
475:
426:
422:
390:
377:DXP-synthase
376:
368:
360:
345:transferases
342:
305:
238:
232:
94:BRENDA entry
65:202218-79-9
18:DXP synthase
1010:transferase
644:Active site
271:pyruvate +
82:IntEnz view
42:Identifiers
1057:Categories
943:Metabolism
847:Isomerases
821:Hydrolases
688:Regulation
411:References
393:structures
308:substrates
235:enzymology
151:structures
118:KEGG entry
726:EC number
361:pyruvate:
283:⇌
262:catalyzes
71:Databases
1063:EC 2.2.1
750:Kinetics
674:Cofactor
637:Activity
548:aldehyde
506:10648511
369:1-deoxy-
349:aldehyde
327:1-deoxy-
323:products
312:pyruvate
295:1-deoxy-
252:) is an
239:1-deoxy-
222:proteins
210:articles
198:articles
155:RCSB PDB
33:1-deoxy-
949:enzymes
906:Biology
860:Ligases
630:Enzymes
463:9371765
431:Bibcode
353:ketonic
256:in the
250:2.2.1.7
177:QuickGO
142:profile
125:MetaCyc
60:CAS no.
53:2.2.1.7
892:Portal
834:Lyases
552:ketone
504:
494:
461:
451:
375:, and
254:enzyme
205:PubMed
187:Search
173:AmiGO
161:PDBsum
101:ExPASy
89:BRENDA
77:IntEnz
48:EC no.
1008:This
786:Types
565:2.2.1
497:94361
454:24228
260:that
137:PRIAM
1014:stub
878:list
871:EC7
865:list
858:EC6
852:list
845:EC5
839:list
832:EC4
826:list
819:EC3
813:list
806:EC2
800:list
793:EC1
558:2.2)
502:PMID
459:PMID
405:2O1X
403:and
401:2O1S
333:and
325:are
314:and
264:the
237:, a
217:NCBI
158:PDBe
113:KEGG
492:PMC
484:doi
480:182
449:PMC
439:doi
397:PDB
351:or
233:In
193:PMC
149:PDB
1059::
945:-
556:EC
546::
500:.
490:.
478:.
474:.
457:.
447:.
437:.
427:94
425:.
421:.
407:.
383:.
340:.
335:CO
247:EC
175:/
1045:e
1038:t
1031:v
1020:.
935:e
928:t
921:v
894::
880:)
876:(
867:)
863:(
854:)
850:(
841:)
837:(
828:)
824:(
815:)
811:(
802:)
798:(
622:e
615:t
608:v
554:(
550:-
536:e
529:t
522:v
508:.
486::
465:.
441::
433::
371:d
363:d
337:2
329:d
317:d
301:2
297:d
273:d
245:(
241:d
35:d
20:)
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