Knowledge

Dawn Bowdish

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Thevaranjan N., Puchta A., Schulz C., Naidoo A., Szamosi J. C., Verschoor C. P., Loukov D., Schenck L. P., Jury J., Foley K. P., Schertzer J. D., Larché M. J., Davidson D. J., Verdú E. F., Surette M. G., Bowdish D. M. E. (2017).
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Verschoor C. P., Johnstone J., Loeb M., Bramson J. L., Bowdish D. M. (2014). "Anti-pneumococcal deficits of monocyte-derived macrophages from the advanced-age, frail elderly and related impairments in PI3K-AKT signaling".
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Bowdish was appointed to the Department of Pathology & Molecular Medicine at McMaster University in 2009. Since, Bowdish has uncovered how aging alters
788: 803: 773: 758: 217: 54: 239:"The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes" 576:"Alterations to the Frequency and Function of Peripheral Blood Monocytes and Associations with Chronic Disease in the Advanced-Age, Frail Elderly" 778: 461:"MARCO, TLR2, and CD14 Are Required for Macrophage Cytokine Responses to Mycobacterial Trehalose Dimycolate and Mycobacterium tuberculosis" 793: 134:, (born May 21, 1976) is a Canadian immunologist and currently a professor in the Department of Pathology and Molecular Medicine at 347:
Bowdish D.M., Davidson D.J., Hancock R.E. (2005). "A re-evaluation of the role of host defence peptides in mammalian immunity".
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Bowdish D.M., Sakamoto K., Kim M. J., Kroos M., Mukhopadhyay S., Leifer C. A., Tryggvason K., Gordon S., Russell D. G. (2009).
159: 798: 650:"Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction" 179: 574:
Verschoor C.P., Johnstone J., Millar J., Parsons R., Lelic A., Loeb M., Bramson J. L., Bowdish D. M. (2014).
753: 190: 691: 627: 554: 504: 439: 376: 327: 272: 748: 587: 167: 163: 155: 115: 58: 166:, she discovered the immunomodulatory role of the host defence peptide LL-37. Bowdish worked at the 135: 97: 679: 615: 542: 492: 427: 364: 315: 260: 111: 669: 661: 605: 595: 534: 482: 472: 417: 409: 356: 305: 250: 719: 591: 723: 674: 649: 610: 575: 487: 460: 422: 397: 158:
with an Honours Bachelor of Science in microbiology. Bowdish obtained her PhD from the
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Bowdish D.M., Davidson D. J., Lau Y.E., Lee K., Scott M. G., Hancock R. E. (2005).
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Bowdish D. M., Davidson D. J., Speert D. P., Hancock R. E. (2004).
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Bowdish D. M., Davidson D. J., Scott M. G., Hancock R. E. (2005).
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Bowdish Lab - Macrophage Biology at McMaster University
193:, and demonstrated that age-associated gut microbe 103: 93: 75: 50: 28: 21: 197:in mice increases age-associated inflammation. 8: 696:: CS1 maint: multiple names: authors list ( 632:: CS1 maint: multiple names: authors list ( 559:: CS1 maint: multiple names: authors list ( 509:: CS1 maint: multiple names: authors list ( 444:: CS1 maint: multiple names: authors list ( 381:: CS1 maint: multiple names: authors list ( 332:: CS1 maint: multiple names: authors list ( 294:"Impact of LL-37 on anti-infective immunity" 277:: CS1 maint: multiple names: authors list ( 18: 673: 609: 599: 486: 476: 421: 309: 254: 162:in 2005. There, under the supervision of 55:University of British Columbia, Vancouver 170:from 2005-2008 under the supervision of 206: 764:21st-century Canadian women scientists 689: 625: 552: 502: 437: 374: 325: 270: 784:University of British Columbia alumni 769:Academic staff of McMaster University 402:Antimicrobial Agents and Chemotherapy 349:Current Protein & Peptide Science 7: 212: 210: 789:Alumni of the University of Oxford 14: 804:Canadian academic journal editors 774:Scientists from Hamilton, Ontario 759:21st-century Canadian biologists 178:in eliciting an immune response 154:In 1999, she graduated from the 414:10.1128/AAC.49.5.1727-1732.2005 189:to increase susceptibility to 174:where she studied the role of 160:University of British Columbia 1: 601:10.1371/journal.pone.0104522 539:10.1016/j.humimm.2014.10.004 478:10.1371/journal.ppat.1000474 298:Journal of Leukocyte Biology 779:University of Guelph alumni 256:10.4049/jimmunol.172.6.3758 820: 666:10.1016/j.chom.2017.03.002 180:Mycobacterium tuberculosis 794:Canadian women biologists 125: 68: 722:publications indexed by 361:10.2174/1389203053027494 654:Cell Host & Microbe 744:Canadian immunologists 739:Canada Research Chairs 191:pneumococcal pneumonia 243:Journal of Immunology 16:Canadian immunologist 168:University of Oxford 164:Robert E. W. Hancock 156:University of Guelph 116:Robert E. W. Hancock 59:University of Oxford 799:Women immunologists 592:2014PLoSO...9j4522V 311:10.1189/jlb.0704380 136:McMaster University 98:McMaster University 132:Dawn M. E. Bowdish 23:Dawn M. E. Bowdish 129: 128: 104:Academic advisors 70:Scientific career 811: 702: 701: 695: 687: 677: 644: 638: 637: 631: 623: 613: 603: 571: 565: 564: 558: 550: 527:Human Immunology 521: 515: 514: 508: 500: 490: 480: 456: 450: 449: 443: 435: 425: 393: 387: 386: 380: 372: 344: 338: 337: 331: 323: 313: 289: 283: 282: 276: 268: 258: 234: 228: 227: 225: 224: 214: 45:Hamilton, Canada 42: 38: 36: 19: 819: 818: 814: 813: 812: 810: 809: 808: 729: 728: 711: 706: 705: 688: 646: 645: 641: 624: 573: 572: 568: 551: 523: 522: 518: 501: 471:(6): e1000474. 458: 457: 453: 436: 395: 394: 390: 373: 346: 345: 341: 324: 291: 290: 286: 269: 236: 235: 231: 222: 220: 216: 215: 208: 203: 152: 118: 114: 110: 86: 82: 57: 51:Alma mater 46: 43: 40: 34: 32: 24: 17: 12: 11: 5: 817: 815: 807: 806: 801: 796: 791: 786: 781: 776: 771: 766: 761: 756: 751: 746: 741: 731: 730: 727: 726: 724:Google Scholar 717: 710: 709:External links 707: 704: 703: 660:(4): 455–466. 639: 586:(8): e104522. 566: 533:(12): 1192–6. 516: 465:PLOS Pathogens 451: 408:(5): 1727–32. 388: 339: 284: 249:(6): 3758–65. 229: 205: 204: 202: 199: 151: 148: 127: 126: 123: 122: 105: 101: 100: 95: 91: 90: 77: 73: 72: 66: 65: 52: 48: 47: 44: 30: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 816: 805: 802: 800: 797: 795: 792: 790: 787: 785: 782: 780: 777: 775: 772: 770: 767: 765: 762: 760: 757: 755: 754:Living people 752: 750: 747: 745: 742: 740: 737: 736: 734: 725: 721: 718: 716: 713: 712: 708: 699: 693: 685: 681: 676: 671: 667: 663: 659: 655: 651: 643: 640: 635: 629: 621: 617: 612: 607: 602: 597: 593: 589: 585: 581: 577: 570: 567: 562: 556: 548: 544: 540: 536: 532: 528: 520: 517: 512: 506: 498: 494: 489: 484: 479: 474: 470: 466: 462: 455: 452: 447: 441: 433: 429: 424: 419: 415: 411: 407: 403: 399: 392: 389: 384: 378: 370: 366: 362: 358: 354: 350: 343: 340: 335: 329: 321: 317: 312: 307: 303: 299: 295: 288: 285: 280: 274: 266: 262: 257: 252: 248: 244: 240: 233: 230: 219: 213: 211: 207: 200: 198: 196: 192: 188: 187:myeloid cells 183: 181: 177: 173: 172:Siamon Gordon 169: 165: 161: 157: 149: 147: 145: 141: 137: 133: 124: 121: 120:Siamon Gordon 117: 113: 109: 106: 102: 99: 96: 92: 89: 85: 81: 78: 74: 71: 67: 64: 60: 56: 53: 49: 41:(age 48) 31: 27: 20: 720:Dawn Bowdish 692:cite journal 657: 653: 642: 628:cite journal 583: 579: 569: 555:cite journal 530: 526: 519: 505:cite journal 468: 464: 454: 440:cite journal 405: 401: 391: 377:cite journal 355:(1): 35–51. 352: 348: 342: 328:cite journal 304:(4): 451–9. 301: 297: 287: 273:cite journal 246: 242: 232: 221:. Retrieved 184: 153: 131: 130: 108:Lori Burrows 94:Institutions 69: 39:May 21, 1976 749:1976 births 733:Categories 223:2024-09-16 201:References 84:Immunology 35:1976-05-21 195:dysbiosis 684:28407483 620:25105870 580:PLOS ONE 547:25446401 497:19521507 432:15855488 369:15638767 320:15569695 265:15004180 675:5392495 611:4126708 588:Bibcode 488:2688075 423:1087655 140:Ontario 112:Joe Lam 80:Biology 63:England 682:  672:  618:  608:  545:  495:  485:  430:  420:  367:  318:  263:  150:Career 144:Canada 76:Fields 176:MARCO 88:Aging 698:link 680:PMID 634:link 616:PMID 561:link 543:PMID 511:link 493:PMID 446:link 428:PMID 383:link 365:PMID 334:link 316:PMID 279:link 261:PMID 29:Born 670:PMC 662:doi 606:PMC 596:doi 535:doi 483:PMC 473:doi 418:PMC 410:doi 357:doi 306:doi 251:doi 247:172 146:. 138:in 735:: 694:}} 690:{{ 678:. 668:. 658:21 656:. 652:. 630:}} 626:{{ 614:. 604:. 594:. 582:. 578:. 557:}} 553:{{ 541:. 531:75 529:. 507:}} 503:{{ 491:. 481:. 467:. 463:. 442:}} 438:{{ 426:. 416:. 406:49 404:. 400:. 379:}} 375:{{ 363:. 351:. 330:}} 326:{{ 314:. 302:77 300:. 296:. 275:}} 271:{{ 259:. 245:. 241:. 209:^ 182:. 142:, 61:, 37:) 700:) 686:. 664:: 636:) 622:. 598:: 590:: 584:9 563:) 549:. 537:: 513:) 499:. 475:: 469:5 448:) 434:. 412:: 385:) 371:. 359:: 353:6 336:) 322:. 308:: 281:) 267:. 253:: 226:. 33:(

Index

University of British Columbia, Vancouver
University of Oxford
England
Biology
Immunology
Aging
McMaster University
Lori Burrows
Joe Lam
Robert E. W. Hancock
Siamon Gordon
McMaster University
Ontario
Canada
University of Guelph
University of British Columbia
Robert E. W. Hancock
University of Oxford
Siamon Gordon
MARCO
Mycobacterium tuberculosis
myeloid cells
pneumococcal pneumonia
dysbiosis


"Keeping grandparents and grandchildren together for as long as possible"
"The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes"
doi
10.4049/jimmunol.172.6.3758

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