472:, managed the inaugural year of the Catalyst and Discovery Awards, and the first two President's Frontier Awards. He has expanded the university's research development efforts, creating a weekly digest of limited submission opportunities, a list of more than 175 funding opportunities for postdoctoral researchers, a list of more than 330 funding opportunities for early career faculty, and consolidated monthly digests of internal funding opportunities at the institution. He also consolidated multiple research administration offices into a central research administration team, Johns Hopkins University Research Administration. As director of the university's Signature Initiatives, he has overseen the launch of two new signature initiatives on
443:"Throughout his time at Johns Hopkins, Denis has distinguished himself as an outstanding scholar and teacher. Additionally, Denis’ role as a catalyst for interdisciplinary research and collaboration at the university has proven extremely effective, both in terms of the research he conducts and the support he has attracted over the years. I am confident that his current research into the physical basis for cell adhesion and de-adhesion will prove critical to our understanding of the metastasis of
459:"As is obvious to all who know him, Denis is an extremely productive and accomplished faculty member and a wonderful colleague. Those traits will serve both Denis and the university as he works with me to support important multidisciplinary research projects, including the strategic initiatives identified in the campaign, the Bloomberg Distinguished Professorships, and multidivisional proposals in response to RFAs (requests for applications)."
515:"For too long, not enough room has been made for nonconventional and nonbiological concepts borrowed from modern physics and engineering to tackle this disease. It is time to bring to the table ideas grounded in chemical and biomolecular engineering principles to develop new therapies and diagnostic tools. given us major funding for a center to study all the steps in the metastatic cascade."
25:
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816:. His research interests include cell biophysics, aging, tumor microenvironment, digital pathology, the actin cap, single molecule manipulation, intracellular particle trafficking, instrument development, tissue engineering, and nanotechnology in biology and medicine. He has made important contributions to molecular and biophysical mechanisms of
427:
Wirtz joined the faculty of the
Department of Chemical and Biomolecular Engineering at Johns Hopkins University in 1994 and was promoted to the rank of full professor in 2003. In 2009, he was selected to be the Theophilus Halley Smoot Professor of Engineering Science with secondary appointments in
360:
Wirtz was named vice provost for research in
February 2014, charged with directing the university's $ 2.24 billion research enterprise, implementing institutional research compliance, expanding research development, and producing and managing cross-divisional research initiatives, such as the Johns
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Wirtz was the first to establish how a three-dimensional environment fundamentally affects the way cancer cells migrate, providing more biologically and medically relevant information than two-dimensional studies. He also pioneered the technique of particle-tracking
643:
in 2009 "for contributions to cell micromechanics and cell adhesion and for the development and application of particle tracking methods to probe the micromechanical properties of living cells in normal conditions and disease state." Wirtz was elected fellow of the
648:
in 2010 for "his seminal contributions to the understanding of basic cellular functions through the development and application of novel biophysical methods grounded in statistical mechanics and polymer physics." In 2011, he was elected member of the
807:
Bridging the fields of chemical engineering, oncology, pathology, biophysics, and materials science, Wirtz's research focuses on the biophysical properties of healthy and diseased cells, including interactions between adjacent cells and the role of
3084:
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in order to “determine the status and trends of applying physical sciences and engineering principles to oncology research and development in leading laboratories and organizations in Europe via an on-site peer review process.”
519:
The PSOC is part of the Johns
Hopkins Institute for NanoBioTechnology (INBT), which Wirtz co-founded and acts as associate director. INBT was launched in 2006 to "promote multidisciplinary research at the interface of
748:. Wirtz also served as an expert advisor to the study panel of the international Assessment of Physical sciences and Engineering advances in Life sciences and Oncology (APHELION), which was commissioned by the
686:
Office of
Technology Commercialization. The team invented a Cell Sensor Based Pathogen Detection that will enable “selective pathogran detection by exploiting the signalizing machinery of living cells.
571:
Research
Experiences for Undergraduates (REU) site in the Nanotechnology for Biology and Bioengineering program. Wirtz also founded the Johns Hopkins Center for Digital Pathology that brings together
1646:
349:
properties of complex fluids and living cells and tissues. He is a professor in the
Departments of Chemical Engineering & Biomolecular Engineering and Materials Science & Engineering in the
682:’s Biomedical Engineering Award. In collaboration with Benjamin Shapiro, Elisabeth Smela and Pamela Ann Abshire, Wirtz was awarded the 2004 Physical Science Invention of the Year Award by the
636:
198:
639:
in 2006 for "major contributions in molecular cell mechanics and the development of particle tracking methods for cell and molecular biology." In 2009, he was elected fellow of the
640:
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Wirtz also directs the Johns
Hopkins Physical Sciences-Oncology Center (PSOC), which is part of a network of twelve centers in the United States funded by the
1125:
2013, S.B. Khatau, R.J. Bloom, S. Bajpai, D. Razafsky, S. Zang, A. Giri, P.-H. Wu, J. Marchand, A. Celedon, C.M. Hale, S.X. Sun, D. Hodzic, and D. Wirtz,
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615:. The program aimed to produce researchers able to create new particles and materials to be used in the detection, treatment, prevention, and cure of
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Science, Nature, Nature Cell
Biology, Nature Methods, Nature Reviews Cancer, Nature Materials, Nature Protocols, PNAS, Nature Communications
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764:
2015 4th Global
Congress on NanoEngineering for Medicine and Biology; 2015 Cell Mechanics, Morphogenesis and Pattern Formation Workshop,
3069:
492:’s Science of Learning Institute, Scott Zeger’s Individualized Health Initiative, and David Peters’ Global Health Signature Initiative.
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Wirtz's lab identified fundamental differences between conventional 2D migration and more physiologically relevant 3D migration in
428:
the departments of
Materials Science and Engineering, Pathology and Oncology, where he collaborates with fellow researchers in the
385:, Belgium. He is fluent in English and French, and became a U.S. citizen in 2007. Wirtz earned a physics engineering degree at the
451:
In February 2014, Wirtz was named the vice provost for research at Johns Hopkins . In announcing the Wirtz's appointment, Provost
1533:“Higher Education Research and Development Survey: Higher education R&D expenditures, ranked by FY 2014 R&D expenditures”
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390:
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Upon his appointment as the Theophilius Halley Smoot Professor of Engineering Physics, Dr. Nicholas Jones, former dean of the
2687:"Final Report Assessment of Physical sciences and Engineering advances in Life sciences and Oncology (APHELION) Europe Study"
468:
In his role as vice provost for research, Wirtz has recruited nearly two dozen faculty to join Johns Hopkins University as
2605:
2164:
2116:
1245:
Single molecule binding of CD44 to fibrin versus P-selectin predicts their distinct shear-dependent interactions in cancer
529:
496:
436:
350:
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1822:
3011:
2747:"Cell Mechanics, Morphogenesis and Pattern Formation: perspectives from the experimental and theoretical points of view"
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2727:"Bad kids or bad neighborhood? How cells turn rogue, escape incarceration, and become a cancer upon their surroundings"
2303:
1078:
2009, S.B. Khatau, C.M. Hale, P.J. Stewart-Hutchison, M.S. Patel, C.L. Stewart, P.C. Searson, D. Hodzic, and D. Wirtz,
2500:
2449:
1612:
1536:
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1327:
753:
672:
568:
548:, the institute is home to several center grants and numerous education, training, and outreach programs. INBT counts
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2013, A.B. Chambliss, S.B. Khatau, P.-H. Wu, N. Erdenberger, D.K. Robinson, D. Hodzic, G.D. Longmore, and D. Wirtz,
2258:
788:(CNC) annual conference in Coimbra, Portugal; distinguished lecturer at the Cancer Nanotechnology Training Center,
545:
35:
2383:
1421:
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600:
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1823:"Theophilus Halley Smoot Professorship in Engineering: Established in 1981 by the estate of Theophilus H. Smoot"
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260:
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1955:
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The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration
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1975:
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2008, S. Bajpai, J. Correia, Y. Feng, J. Figueiredo, S.X. Sun, G.D. Longmore, G. Suriano, and D. Wirtz,
1101:
973:
Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells
947:
934:
809:
564:
among its corporate partners, and Wirtz has previously served as a Nikon Partner in Science since 2008.
2396:
1564:
1219:
a-catenin mediates initial E-cadherin-dependent cell-cell recognition and subsequent bond strengthening
2096:
1630:“Michael R. Bloomberg commits $ 350 million to Johns Hopkins for transformational academic initiative”
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Dimensional and temporal controls of three-dimensional cell migration by Zyxin and binding partners
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and enable important breakthroughs in the diagnosis and treatment of cancer in the years to come."
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2520:
2484:“Johns Hopkins stem cell researcher Sharon Gerecht receives inaugural President's Frontier Award”
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1131:
1118:
696:
481:
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is the vice provost for research and Theophilus Halley Smoot Professor of Engineering Science at
2343:
1995:
1907:
2437:
2238:
1924:
1532:
999:
Statistical analysis of cell migration in 3D using the anisotropic persistent random walk model
361:
Hopkins Catalyst and Discovery Awards program, the President's Frontier Award program, and the
2666:
1416:
1379:
1232:
Loss of a-catenin decreases the strength of single E-cadherin bonds between human cancer cells
971:
2014, D.M. Gilkes, L. Xiang, S.J. Lee, M.E. Hubbi, P. Chaturvedi, D. Wirtz, and G.L. Semenza,
883:-rich matrices) that is not predicted or extrapolated from the better known 2D case (use of a
504:
366:
250:
157:
2219:"Award Abstract #1460716: REU Site: Program in Nanotechnology for Biology and Bioengineering"
2181:
824:
and nuclear dynamics in health and disease, and he pioneered the method of particle-tracking
678:
for: “A Research and Teaching Program in Complex Fluids Dynamics.”. In 1997, he received the
2627:
2015:
1941:
1598:
1297:
The physics of cancer: the role of physical interactions and mechanical forces in metastasis
1097:
The multi-faceted role of the actin cap in cellular mechanosensation and mechanotransduction
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cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction
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829:
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342:
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172:
2726:
2076:"JHU's Charles Bennett and Andrew Feinberg named Bloomberg Distinguished Professors"
1942:"Johns Hopkins biologist Scott Bailey receives $ 250,000 President's Frontier Award"
1599:"Johns Hopkins biologist Scott Bailey receives $ 250,000 President's Frontier Award"
627:, while making a special effort to include minorities under-represented in science.
38:
or has been extensively edited by the subject or by someone connected to the subject
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1582:“New Johns Hopkins awards to provide $ 15 million to support faculty-led research”
2950:
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1349:
Micromechanical mapping of live cells by multiple-particle-tracking microrheology
1310:
A distinctive role for focal adhesion proteins in three-dimensional cell motility
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192:
2707:"The ASME 2015 4th Global Congress on NanoEngineering for Medicine and Biology"
1629:
907:
2010, S.I. Fraley, Y. Feng, D.H. Kim, A. Celedon, G.D. Longmore, and D. Wirtz,
735:
Proceedings of the National Academy of Sciences of the United States of America
2564:
1207:
884:
856:
511:. When the center was established with a $ 14.8M grant in 2009, Wirtz stated,
420:’s Human Capital and Mobility program to conduct postdoctoral research at the
326:
161:
1908:“Johns Hopkins Discovery Awards given to 23 cross-divisional research teams”
1323:
Particle-tracking microrheology of living cells: principles and applications
896:
Programmed sub-cellular release for studying the dynamics of cell detachment
553:
401:
242:
2706:
1457:“Moving cancer research out of the Petri dish and into the third dimension”
1258:
a-catenin serves as a clutch between low and high intercellular E-cadherin
1140:
Tight coupling between nucleus and cell migration through the perinuclear
744:
on physical oncology, and as the editor of the Cell Biophysics section of
1230:
2009, S. Bajpai, Y. Feng, R. Krishnamurthy, G.D. Longmore, and D. Wirtz,
1047:
cap as key mediators of physical signaling between the cytoplasm and the
880:
612:
528:." With more than 250 affiliated faculty members from the Johns Hopkins
525:
508:
473:
382:
246:
117:
3085:
Fellows of the American Institute for Medical and Biological Engineering
2746:
2262:
2870:
2830:"CNC Keynote Speaker: Engineering approaches to molecular cell biology"
2561:"World Journal of Biological Chemistry: Members of the Editorial Board"
1064:
930:: the role of physical interactions and mechanical forces in metastasis
616:
588:
378:
89:
2521:"Cell Health and Cytoskeleton, Editor-in-Chief: Professor Denis Wirtz"
2464:"Chemical and biomolecular engineer Denis Wirtz named Smoot professor"
1925:“Catalyst Awards granted to 37 early-career Johns Hopkins researchers”
1837:"Chemical and biomolecular engineer Denis Wirtz named Smoot professor"
1803:"Chemical and biomolecular engineer Denis Wirtz named Smoot professor"
1783:"The Sidney Kimmel Comprehensive Cancer Center: Laboratory Scientists"
1723:"Chemical and biomolecular engineer Denis Wirtz named Smoot professor"
1514:“Johns Hopkins leads U.S. in research spending for 36th year in a row”
607:(HHMI) funded interdisciplinary graduate research training program in
927:
836:
592:
444:
3034:
2910:
2304:"HHMI Awards $ 10 Million for Interdisciplinary Graduate Education"
2198:
1565:“Johns Hopkins scholars, leaders celebrate faculty research awards”
1336:
Efficient active transport of gene nanocarriers to the cell nucleus
1278:
Wirtz has published nearly 200 peer-reviewed articles published in
599:. He co-directs the Cancer Nanotechnology Training Center, another
579:, and engineers to develop new single-cell technology for improved
3075:
Fellows of the American Association for the Advancement of Science
1362:
Mechanics of living cells measured by laser tracking microrheology
1170:
Cytoskeletal tension induces the 3D polarized architecture of the
1141:
1111:
1081:
1044:
781:
1613:"Johns Hopkins names four new Bloomberg Distinguished Professors"
941:
2012, S.I. Fraley, Y. Feng, A. Giri, G.D. Longmore, and D Wirtz,
2787:"The Cellular and Molecular Basis of Invasive Metastatic Cancer"
1653:, Washington, D.C., 23 January 2013. Retrieved on 12 March 2015.
1340:
1223:
1088:
990:
977:
761:
2386:, Washington DC, 31 December 2010. Retrieved on 25 March 2016.
1016:
Wirtz developed novel tools and concepts to study the role of
986:
Three-dimensional cell migration does not follow a random walk
18:
2182:“Institute for NanoBioTechnology adds two to leadership team”
2056:"Institute of Data Intensive Engineering and Science (IDIES)"
1647:"Bloomberg pledges $ 350 million to Johns Hopkins University"
1375:
Reversible hydrogels from self-assembling artificial proteins
776:
Cell Biology Annual Meeting; 2014 Longrifles Cancer Seminar,
2631:, United Kingdom, 1 August 2011. Retrieved on 28 March 2016.
2501:"Faculty & Students Win Invention, Business Plan Awards"
2438:“Faculty Early Career Development (CAREER) Awards (FY 1996)”
1243:
2011, P.S. Raman, C.S. Alves, D. Wirtz, K. Konstantopoulos,
1059:
is polarized through the actin cap, which in turn polarizes
879:(MMPs) play a central role in 3D migration (migration in 3D
422:
Ecole Supérieure de Physique et Chimie Industrielles (ESPCI)
365:, which were established as part of a $ 350 million gift by
2324:"Denis Wirtz, Ph.D. AIMBE College of Fellows Class of 2006"
2453:, Arlington, 31 December 1996. Retrieved on 25 March 2016.
2369:, Baltimore, 21 December 2009. Retrieved on 25 March 2016.
2352:, Baltimore, 19 December 2009. Retrieved on 25 March 2016.
2188:, Baltimore, 20 November 2010. Retrieved on 28 March 2016.
1571:, Baltimore, 4 September 2015. Retrieved on 25 March 2016.
1157:
Nuclear envelope in nuclear positioning and cell migration
784:
Symposium on Mechanics of Soft Active Materials; 2013 The
353:, and in the Departments of Oncology and Pathology in the
2490:, Baltimore, 28 January 2015. Retrieved on 25 March 2016.
1743:"Materials Science & Engineering: Associated Faculty"
1664:"$ 1.1 Billion in Thanks From Bloomberg to Johns Hopkins"
1636:, Baltimore, 26 January 2013. Retrieved on 27 March 2016.
1588:, Baltimore, 27 January 2015. Retrieved on 27 March 2016.
1520:, Baltimore, 9 December 2015. Retrieved on 27 March 2016.
637:
American Institute for Medical and Biological Engineering
199:
American Institute for Medical and Biological Engineering
2055:
1462:, Baltimore, 1 January 2013. Retrieved on 28 March 2016.
1036:, and mechanotransduction. In particular, he identified
660:
Biophysical Society, American Society for Microbiology,
1672:, New York, 26 January 2013. Retrieved on 1 March 2015.
1256:
2013, S. Bajpai, Y. Feng, D. Wirtz, and G.D. Longmore,
2397:"Belgian American Educational Foundation BAEF Members"
1931:, Baltimore, 25 June 2015. Retrieved on 25 March 2016.
1885:"Wirtz relishes new role as vice provost for research"
1619:, Baltimore, 30 March 2015. Retrieved on 27 July 2015.
1540:, Arlington, 31 July 2015. Retrieved on 25 March 2016.
603:-funded entity. From 2005 to 2012, he also directed a
1914:, Baltimore, 6 July 2015. Retrieved on 25 March 2016.
2604:
Department of Chemical and Biomolecular Engineering
2344:“Seven Johns Hopkins Researchers Named AAAS Fellows”
595:, Chronic obstructive pulmonary disease (COPD), and
42:
It may need editing to conform to Knowledge (XXG)'s
2871:"Royal Academy of Medicine of Belgium: Denis Wirtz"
795:In 2019, we was elected as a foreign member of the
712:. Wirtz formerly served on the editorial boards of
641:
American Association for the Advancement of Science
288:
266:
256:
230:
189:
American Association for the Advancement of Science
178:
151:
135:
125:
96:
80:
2612:, Baltimore, Fall 2009. Retrieved on 28 March 2016
2171:, Baltimore, Fall 2009. Retrieved on 28 March 2016
2123:, Baltimore, Fall 2009. Retrieved on 28 March 2016
2036:"Johns Hopkins University Research Administration"
954:2013, K. Konstantopoulos, P.-H. Wu, and D. Wirtz,
924:2011, D. Wirtz, K. Konstantopoulos, P.C. Searson,
730:Nanomedicine: Nanotechnology, Biology and Medicine
1956:"Limited Submissions at Johns Hopkins University"
1388:Particle tracking microrheology of complex fluids
2541:"Cell Adhesion & Migration: Editorial Board"
2284:"Cancer Nanotechnology Training Centers (CNTCs)"
46:policy. There may be relevant discussion on the
690:Since 2008, he has been the Editor-in-Chief of
416:. He was then granted a fellowship through the
1095:2013, D.H. Kim, A.B. Chambliss, and D. Wirtz,
2363:“INBT, EOC directors named AAAS 2009 Fellows”
1857:"Denis Wirtz named vice provost for research"
1162:Advances in Experimental Medicine and Biology
8:
2998:, 25 March 2016. Retrieved on 25 March 2016.
1155:2014, D. Razafsky, D. Wirtz, and D. Hodzic,
984:2014, P.H. Wu, A. Giri, S.X. Sun, D. Wirtz,
894:2009, B. Wildt, D. Wirtz, and P.C. Searson,
772:; 2015 MRS Fall Meeting & Exhibit; 2015
738:, as the guest editor of a Special Issue of
720:Journal of the Royal Society Interface Focus
337:and nuclear dynamics in health and disease.
480:, and space studies, Space@Hopkins, led by
77:
664:, American Society for Microbiology, and
430:Sidney Kimmel Comprehensive Cancer Center
206:Biomedical Engineering Foundation Award,
66:Learn how and when to remove this message
3080:Fellows of the American Physical Society
2979:, 9 June 2020. Retrieved on 9 June 2020.
2810:"Longrifles Cancer Seminar in Baltimore"
1871:"Bloomberg Distinguished Professorships"
1051:. More recently, he discovered that the
797:Belgian Royal Academy of Medicine (ARMB)
786:Centre for Neuroscience and Cell Biology
658:American Institute of Chemical Engineers
218:Belgian Royal Academy of Medicine (ARMB)
203:National Science Foundation CAREER Award
2239:"National Science Foundation REU Sites"
1551:"Denis Wirtz Vice Provost for Research"
1448:
1437:Belgian American Educational Foundation
997:2015, P.-H. Wu, A. Giri, and D. Wirtz,
828:to probe the rheological properties of
651:Belgian American Educational Foundation
398:Belgian American Educational Foundation
213:Belgian American Educational Foundation
16:Belgian molecular biologist (born 1965)
2931:"Distinguished Lecturer – Denis Wirtz"
2851:"Distinguished Lecturer – Denis Wirtz"
1703:"Distinguished Lecturer – Denis Wirtz"
1628:Office of Communications Staff Report
1407:Bloomberg Distinguished Professorships
1186:Single-molecule adhesion nanomechanics
1138:2014, D.H. Kim, S. Cho, and D. Wirtz,
859:. In particular, they found that the
363:Bloomberg Distinguished Professorships
2767:"2015 MRS Fall Meeting & Exhibit"
2349:Johns Hopkins School of Public Health
2199:"INBT Corporate Partnerships Program"
2165:“Engineers Join Fight Against Cancer”
2117:“Engineers Join Fight Against Cancer”
1976:"Post-doctoral Funding Opportunities"
706:World Journal of Biological Chemistry
7:
1996:"Early Career Funding Opportunities"
1683:"BAEF Fellowships: Alumni 1980–1989"
851:, creating new understanding of the
694:. He is on the Editorial Boards of
623:, chemistry, physics, biology, and
488:’s 21st Century Cities Initiative,
1427:Physical Sciences-Oncology Centers
913:in three-dimensional cell motility
470:Bloomberg Distinguished Professors
396:With a Hoover Fellowship from the
14:
3025:Vice Provost for Research Webpage
2951:"Patents by Inventor Denis Wirtz"
774:American Society for Cell Biology
671:Wirtz is a 1996 recipient of the
662:American Society for Cell Biology
3065:Johns Hopkins University faculty
2016:"Internal Funding Opportunities"
778:Johns Hopkins School of Medicine
692:Cell Health and the Cytoskeleton
635:Wirtz was elected fellow of the
355:Johns Hopkins School of Medicine
88:
23:
2367:Institute for NanoBioTechnology
1237:Journal of Biological Chemistry
1020:and nuclear connections to the
605:Howard Hughes Medical Institute
3095:21st-century Belgian educators
3090:20th-century Belgian educators
2417:"AIChE Community: Denis Wirtz"
2259:"Center for Digital Pathology"
835:Wirtz currently holds several
832:and living cells and tissues.
760:Recent plenary talks include:
732:, as an ad hoc editor for the
656:Wirtz is also a member of the
400:(BAEF), he earned an M.S. and
1:
2586:"TECHNOLOGY: Editorial Board"
2436:National Science Foundation.
1383:. Vol. 281, nº 5375; 389–392.
1168:2015, D.H. Kim and D. Wirtz,
994:. Vol. 111, nº 11; 3949–3954.
702:Cell Adhesion & Migration
619:. It recruited students from
587:, therapeutic approaches for
497:National Institutes of Health
437:Whiting School of Engineering
391:Université libre de Bruxelles
351:Whiting School of Engineering
140:Université libre de Bruxelles
2623:“Preface: Physical oncology”
2133:Cofield, Calla (June 2010).
1344:. Vol. 100, nº 7; 3878–3882.
1190:Using single-molecule force
2621:Lee, Jerry and Denis Wirtz
2450:National Science Foundation
2135:"Cell is Mechanical Device"
1537:National Science Foundation
1530:National Science Foundation
1370:. Vol. 78, nº 4; 1736–1747.
1357:. Vol. 83, nº 6; 3162–3176.
1328:Annual Review of Biophysics
1084:cap regulates nuclear shape
754:National Science Foundation
673:National Science Foundation
569:National Science Foundation
484:. These are in addition to
3111:
3070:Stanford University alumni
2642:"Comprehensive Biophysics"
2378:American Physical Society
1494:"Denis Wirtz Profile Page"
1012:Cell and nuclear mechanics
968:. Vol. 104, nº 2; 279–280.
546:Applied Physics Laboratory
2384:American Physical Society
1422:National Cancer Institute
1318:. Vol. 12, nº 6; 598–604.
1305:. Vol. 11, nº 7; 512–522.
1286:He has an h-index of 83.
750:National Cancer Institute
646:American Physical Society
601:National Cancer Institute
501:National Cancer Institute
321:. He is an expert in the
284:
280:(Postdoctoral Fellowship)
223:
184:American Physical Society
87:
3060:Scientists from Brussels
2663:Comprehensive Biophysics
2661:Egelman, Edward (2012).
1412:Johns Hopkins University
1284:Journal of Cell Biology.
1240:. Vol. 284; 18252–18259.
1227:. Vol. 105; 18331–18336.
1212:Supporting Publications:
1092:. Vol. 107; 19017–19022.
1073:Supporting Publications:
909:The distinctive role of
889:Supporting Publications:
877:matrix metalloproteinase
865:focal adhesion molecules
843:2D vs. 3D cell migration
746:Comprehensive Biophysics
544:and scientists from the
319:Johns Hopkins University
261:Johns Hopkins University
239:biomolecular engineering
2097:"Signature Initiatives"
1396:. Vol. 79, nÂş 17; 3282.
1393:Physical Review Letters
1250:Journal of Cell Science
1196:intracellular molecules
1149:Journal of Cell Science
956:Dimensional control of
911:focal adhesion proteins
770:University of Cambridge
631:Awards and distinctions
278:Pierre-Gilles de Gennes
3012:Pathology and Oncology
2891:"Faculty: Denis Wirtz"
1763:"Faculty: Denis Wirtz"
1460:Johns Hopkins Magazine
1269:. Vol. 105; 2289–2300.
1253:. Vol. 124; 1904–1910.
1198:such as a-catenin and
1152:. Vol. 127; 2528–2541.
1028:, including 2D and 3D
981:. Vol. 111; E384-E393.
853:tumor microenvironment
790:University of Kentucky
766:Isaac Newton Institute
684:University of Maryland
560:, Secant Medical, and
530:schools of Engineering
517:
461:
449:
377:Wirtz was born in the
168:Tumor Microenvironment
2990:"Author: Denis Wirtz"
2971:"Author: Denis Wirtz"
1302:Nature Reviews Cancer
1290:Highly cited articles
1194:, his lab showed how
948:Nature Communications
935:Nature Reviews Cancer
812:on nuclear shape and
810:cellular architecture
567:Wirtz is the PI of a
513:
457:
441:
44:neutral point of view
2665:. Elsevier Science.
2380:“APS Fellow Archive”
1165:. Vol. 773; 471–490.
1122:. Vol. 3; 1087–1095.
1105:. Vol. 9; 5516–5523.
406:Chemical Engineering
235:Chemical engineering
3035:Wirtz Group Website
1651:The Washington Post
1473:"Reddit Cancer AMA"
1367:Biophysical Journal
1354:Biophysical Journal
1315:Nature Cell Biology
1266:Biophysical Journal
1181:. Vol. 48; 161–172.
1007:. Vol. 10; 517–527.
965:Biophysical Journal
938:. Vol. 11; 512–522.
921:. Vol. 12; 598–604.
918:Nature Cell Biology
725:Biophysical Journal
680:Whitaker Foundation
666:Society of Rheology
453:Robert C. Lieberman
410:Stanford University
387:Ecole Polytechnique
208:Whitaker Foundation
145:Stanford University
2443:2016-03-03 at the
1669:The New York Times
1662:Barbaro, Michael.
1475:. 22 February 2016
1331:. Vol 38; 301–326.
1204:cell-cell adhesion
1135:. Vol. 2; 488–499.
1132:Scientific Reports
1119:Scientific Reports
1110:The LINC-anchored
1040:and the so-called
904:. Vol. 6; 211–213.
697:Scientific Reports
482:Charles L. Bennett
424:in Paris, France.
171:Particle-tracking
1580:Sneiderman, Phil
1417:Ronald J. Daniels
534:Arts and Sciences
505:physical sciences
367:Michael Bloomberg
312:
311:
251:materials science
225:Scientific career
165:Nuclear dynamics
162:Cancer Metastasis
158:Digital Pathology
155:3D Cell Motility
111:February 20, 1965
76:
75:
68:
3102:
2999:
2986:
2980:
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2697:
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2683:
2677:
2676:
2658:
2652:
2651:
2649:
2648:
2638:
2632:
2628:Physical Biology
2619:
2613:
2606:“Faculty Awards”
2602:
2596:
2595:
2593:
2592:
2582:
2576:
2575:
2573:
2572:
2563:. Archived from
2557:
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2537:
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2261:. Archived from
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2209:
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2012:
2006:
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2003:
2002:
1992:
1986:
1985:
1983:
1982:
1972:
1966:
1965:
1963:
1962:
1952:
1946:
1945:
1944:. February 2016.
1938:
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1710:
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1689:
1679:
1673:
1660:
1654:
1645:Anderson, Nick.
1643:
1637:
1626:
1620:
1609:
1603:
1602:
1601:. February 2016.
1595:
1589:
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1484:
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1481:
1480:
1469:
1463:
1453:
1061:hyper-acetylated
1049:nuclear interior
1034:mechanosensation
1004:Nature Protocols
741:Physical Biology
715:Physical Biology
611:for biology and
597:frailty in aging
558:Northrop Grumman
550:Becton Dickinson
381:municipality of
308:
305:
303:
301:
299:
297:
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273:Gerald G. Fuller
268:Doctoral advisor
114:
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26:
19:
3110:
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3030:Faculty Webpage
3021:
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2988:Google Scholar
2987:
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2969:Google Scholar
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2445:Wayback Machine
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1512:O’Shea, Dennis
1511:
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1471:
1470:
1466:
1454:
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1276:
926:The physics of
814:gene expression
805:
633:
509:study of cancer
466:
414:polymer physics
375:
300:/administration
292:
276:
215:
211:Hoover Fellow,
210:
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136:Alma mater
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3020:
3019:External links
3017:
3016:
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3007:
3006:External links
3004:
3001:
3000:
2995:Google Scholar
2981:
2976:Google Scholar
2962:
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2672:978-0123749208
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2007:
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1611:Brooks, Kelly
1604:
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1292:
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1272:
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1260:bond strengths
1254:
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1228:
1188:
1187:
1183:
1182:
1166:
1153:
1136:
1123:
1106:
1093:
1080:A perinuclear
1057:adherent cells
1053:nuclear lamina
1038:LINC complexes
1032:and adhesion,
1030:cell migration
1026:cell functions
1014:
1013:
1009:
1008:
995:
982:
969:
952:
951:. Vol. 3; 719.
939:
922:
905:
901:Nature Methods
873:LINC complexes
845:
844:
830:complex fluids
804:
801:
632:
629:
609:nanotechnology
589:human diseases
522:nanotechnology
490:Barbara Landau
465:
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418:European Union
374:
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329:mechanisms of
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197:Fellow of the
187:Fellow of the
182:Fellow of the
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152:Known for
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3050:Living people
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2567:on 2015-12-18
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2342:Parsons, Tim
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2265:on 2016-04-03
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2163:Gebel, Erika
2160:
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2115:Gebel, Erika
2112:
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1859:. 2014-03-06.
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2186:HUB at Work
2169:ChemBE BOND
2121:ChemBE BOND
1432:Cell CANARY
1102:Soft Matter
1042:perinuclear
958:cancer cell
780:; and 2014
625:engineering
577:oncologists
478:Alex Szalay
347:rheological
327:biophysical
315:Denis Wirtz
193:AAAS Fellow
126:Nationality
101:Denis Wirtz
82:Denis Wirtz
3044:Categories
2956:2016-03-31
2936:2016-03-28
2916:2016-03-30
2896:2016-03-30
2876:2020-05-05
2856:2016-03-28
2836:2016-03-31
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2795:2016-03-28
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2021:2016-03-30
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1563:Hub Staff
1499:2016-03-28
1479:2016-03-28
1443:References
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885:Petri dish
857:metastasis
710:TECHNOLOGY
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373:Biography
323:molecular
243:pathology
129:American
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2441:Archived
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2139:APS News
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1065:histones
1024:and key
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613:medicine
538:Medicine
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474:big data
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383:Brussels
335:adhesion
302:/provost
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231:Fields
179:Awards
142:(B.S.)
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