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Dille–Koppanyi reagent

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light purple by complexation of cobalt with the barbiturate nitrogens. The test, in a slightly different formulation, was developed in the 1930s by the Hungarian-American pharmacologist Theodore Koppanyi (1901–1985) and the American Biochemist, James Madison Dille (1928–1986).
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Koppanyi, T.; Dille, J. M.; Murphy, W. S.; Krop, S. (1934). "Studies on barbiturates. II. Contributions to methods of barbital research".
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O’Neal, C. L.; Crouch, D. J.; Fatah, A. A. (2000). "Validation of twelve chemical spot tests for the detection of drugs of abuse".
40:(v/v) in methanol. Two drops of A are dropped onto the substance followed by one drop of B and any change in colour is observed. 326: 283: 175: 321: 316: 171: 263: 79: 223:
Dille, J. M.; Koppanyi, T. (1934). "Studies on barbiturates. III. Chemical assay of barbiturates".
33: 25: 124: 267: 232: 205: 116: 84: 74: 255: 37: 120: 310: 69: 48: 44: 56: 21: 142: 52: 236: 209: 143:"Color Test Reagents/Kits for Preliminary Identification of Drugs of Abuse" 128: 29: 24:. It is composed of a mixture of two solutions. Part A is 0.1 g of 150:
Law Enforcement and Corrections Standards and Testing Program
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is used as a simple spot-test to presumptively identify
271: 225:Journal of the American Pharmaceutical Association 198:Journal of the American Pharmaceutical Association 102: 100: 291: 8: 298: 284: 96: 7: 252: 250: 170:Lancashire, Robert J. (2011-10-13). 270:. You can help Knowledge (XXG) by 14: 28:dihydrate dissolved in 100 ml of 254: 172:"Unit 9: Crime - Reagent Kits" 109:Forensic Science International 1: 176:University of the West Indies 121:10.1016/S0379-0738(99)00235-2 348: 332:Analytical chemistry stubs 249: 36:. Part B made up of is 5% 237:10.1002/jps.3080231104 210:10.1002/jps.3080231103 18:Dille–Koppanyi reagent 327:Drug testing reagents 32:mixed with 0.2 ml of 264:analytical chemistry 322:Analytical reagents 262:This article about 34:glacial acetic acid 26:cobalt(II) acetate 279: 278: 231:(11): 1079–1084. 204:(11): 1074–1079. 80:Froehde's reagent 339: 300: 293: 286: 258: 251: 241: 240: 220: 214: 213: 193: 187: 186: 184: 183: 167: 161: 160: 158: 157: 147: 139: 133: 132: 104: 347: 346: 342: 341: 340: 338: 337: 336: 307: 306: 305: 304: 247: 245: 244: 222: 221: 217: 195: 194: 190: 181: 179: 169: 168: 164: 155: 153: 145: 141: 140: 136: 106: 105: 98: 93: 85:Zwikker reagent 75:Marquis reagent 66: 43:The test turns 12: 11: 5: 345: 343: 335: 334: 329: 324: 319: 317:Chemical tests 309: 308: 303: 302: 295: 288: 280: 277: 276: 259: 243: 242: 215: 188: 162: 134: 115:(3): 189–201. 95: 94: 92: 89: 88: 87: 82: 77: 72: 65: 62: 38:isopropylamine 13: 10: 9: 6: 4: 3: 2: 344: 333: 330: 328: 325: 323: 320: 318: 315: 314: 312: 301: 296: 294: 289: 287: 282: 281: 275: 273: 269: 265: 260: 257: 253: 248: 238: 234: 230: 226: 219: 216: 211: 207: 203: 199: 192: 189: 178:, Mona Campus 177: 173: 166: 163: 151: 144: 138: 135: 130: 126: 122: 118: 114: 110: 103: 101: 97: 90: 86: 83: 81: 78: 76: 73: 71: 70:Drug checking 68: 67: 63: 61: 58: 54: 50: 49:pentobarbital 46: 45:phenobarbital 41: 39: 35: 31: 27: 23: 19: 272:expanding it 261: 246: 228: 224: 218: 201: 197: 191: 180:. Retrieved 165: 154:. Retrieved 149: 137: 112: 108: 57:secobarbital 42: 22:barbiturates 17: 15: 152:. July 2000 53:amobarbital 311:Categories 182:2014-03-17 156:2011-07-24 91:References 129:10725655 64:See also 30:methanol 127:  266:is a 146:(PDF) 268:stub 125:PMID 55:and 16:The 233:doi 206:doi 117:doi 113:109 313:: 229:23 227:. 202:23 200:. 174:. 148:. 123:. 111:. 99:^ 51:, 47:, 299:e 292:t 285:v 274:. 239:. 235:: 212:. 208:: 185:. 159:. 131:. 119::

Index

barbiturates
cobalt(II) acetate
methanol
glacial acetic acid
isopropylamine
phenobarbital
pentobarbital
amobarbital
secobarbital
Drug checking
Marquis reagent
Froehde's reagent
Zwikker reagent


doi
10.1016/S0379-0738(99)00235-2
PMID
10725655
"Color Test Reagents/Kits for Preliminary Identification of Drugs of Abuse"
"Unit 9: Crime - Reagent Kits"
University of the West Indies
doi
10.1002/jps.3080231103
doi
10.1002/jps.3080231104
Stub icon
analytical chemistry
stub
expanding it

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