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Cumulus oophorus

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Cumulus oophorus cells contribute heavily to the maturation and eventual fertilization of an oocyte. As a follicle grows in size and the antrum develops, more layers of cumulus oophorus cells accumulate around the oocyte to aid in the acrosome reaction and sperm penetration into the oocyte. The
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The Evian Annual Reproduction (EVAR) Workshop Group 2010; Fauser, B. C. J. M.; Diedrich, K.; Bouchard, P.; Domínguez, F.; Matzuk, M.; Franks, S.; Hamamah, S.; Simón, C.; Devroey, P.; Ezcurra, D.; Howles, C. M. (2011).
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Functions of the cumulus oophorus include coordination of follicular development and oocyte maturation. Mechanisms of the latter include stimulation of
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proximity between the cumulus oophorus cells and the oocyte favors bidirectional communication, which is vital for oocyte development.
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of cumulus cells, genes where increased expression is correlated with higher oocyte competence or better pregnancy outcomes, include:
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In contrast, genes where increased expression is correlated with lower oocyte competence or worse pregnancy outcomes include:
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It also provides energy substrates for oocyte meiotic resumption and promotes glycolysis.
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of cumulus cells can be performed to estimate oocyte quality and the efficiency of an
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The innermost layer of these cells is the 137:, it may be regarded as an extension of the 392:: CS1 maint: numeric names: authors list ( 1076: 1067: 815: 517: 508: 499: 478: 464: 456: 148:This layer of cells must be penetrated by 121:) is a cluster of cells that surround the 38: 369: 1529: 305: 385: 100: 29: 27:Cluster of cells surrounding an oocyte 7: 1248:Infra-corporeal residual spongy part 25: 1555:Mammal female reproductive system 1532: 1244:Trabeculae of corpora cavernosa 1: 194:As a part of the process of 1392:Internal urethral sphincter 1571: 487:Female reproductive system 434:dbefruchtung/objectbefru01 1397:External urethral orifice 1387:External sphincter muscle 1382:Internal urethral orifice 1191:Vestibular gland openings 1153:Posterior labial arteries 450:Histology image: 18404loa 350:Human Reproduction Update 200:gene expression profiling 190:Gene expression profiling 175:and regulation of oocyte 95: 37: 1311:Superficial dorsal veins 1301:Internal pudendal artery 204:ovarian hyperstimulation 1464:Uterine venous plexuses 1326:Internal pudendal veins 1124:Posterior labial nerves 1158:Posterior labial veins 1129:Anterior labial nerves 958:Pubocervical ligaments 440:UIUC Histology Subject 196:in vitro fertilization 97:Anatomical terminology 1469:Vaginal venous plexus 953:Uterosacral ligaments 362:10.1093/humupd/dmr033 315:Developmental Biology 44:Section of vesicular 1512:Uterotubal junctions 1114:Posterior commissure 979:Urogenital diaphragm 868:Supravaginal portion 790:Vesicular appendages 755:Suspensory ligaments 699:Fallopian tubes 219:expression profiling 166:amino acid transport 1507:Vesicouterine pouch 1258:Commissure of bulbs 1223:Suspensory ligament 1109:Anterior commissure 732:Intramural segments 612:Germinal epithelium 596:Perivitelline space 1502:Rectouterine pouch 1228:Fundiform ligament 1044:Support structures 999:Bartholin's glands 948:Cardinal ligaments 760:Pampiniform plexus 591:Membrana granulosa 313:Gilbert, Scott F. 177:gene transcription 139:membrana granulosa 1520: 1519: 1409: 1408: 1405: 1404: 1316:Deep dorsal veins 1296:Arteries of bulbs 1240:Corpora cavernosa 1163:Interlabial sulci 1104:Labiocrural folds 1057: 1056: 992:Vestibular glands 987: 986: 805: 804: 772:Wolffian vestiges 750:Ovarian ligaments 693: 692: 569:Follicular antrum 119:discus proligerus 111: 110: 106: 16:(Redirected from 1562: 1537: 1536: 1528: 1424:Ovarian arteries 1357:Tunica albuginea 1119:Dartos muliebris 1077: 1068: 816: 627:Cumulus oophorus 617:Tunica albuginea 574:Follicular fluid 518: 509: 500: 480: 473: 466: 457: 417:Swiss embryology 398: 397: 391: 383: 373: 340: 329: 328: 310: 212:embryo selection 127:ovarian follicle 115:cumulus oophorus 103:edit on Wikidata 74:cumulus oophorus 46:ovarian follicle 42: 33:Cumulus oophorus 30: 21: 1570: 1569: 1565: 1564: 1563: 1561: 1560: 1559: 1545: 1544: 1543: 1531: 1523: 1521: 1516: 1497:Perineal sponge 1492:Urethral sponge 1475: 1444:Spiral arteries 1401: 1363: 1286:Dorsal arteries 1263:Pars intermedia 1194: 1180:Vaginal orifice 1053: 1008: 983: 962: 943:Broad ligaments 938:Round ligaments 924: 879: 801: 780:Gartner's ducts 766: 736: 689: 648: 600: 489: 484: 407: 402: 401: 384: 342: 341: 332: 325: 312: 311: 307: 302: 192: 162: 135:antral follicle 107: 78:discus proliger 76: 53: 28: 23: 22: 18:Discus proliger 15: 12: 11: 5: 1568: 1566: 1558: 1557: 1547: 1546: 1542: 1541: 1518: 1517: 1515: 1514: 1509: 1504: 1499: 1494: 1489: 1483: 1481: 1477: 1476: 1474: 1473: 1472: 1471: 1466: 1461: 1456: 1448: 1447: 1446: 1441: 1439:Vaginal artery 1436: 1434:Arcuate artery 1431: 1429:Uterine artery 1426: 1417: 1415: 1411: 1410: 1407: 1406: 1403: 1402: 1400: 1399: 1394: 1389: 1384: 1379: 1377:Urethral crest 1373: 1371: 1365: 1364: 1362: 1361: 1358: 1355: 1350: 1345: 1344: 1343: 1341:Pudendal nerve 1338: 1330: 1329: 1328: 1323: 1321:Veins of bulbs 1318: 1313: 1305: 1304: 1303: 1298: 1293: 1288: 1280: 1279: 1278: 1273: 1265: 1260: 1255: 1254: 1253: 1250: 1245: 1242: 1232: 1231: 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In the 131:ovulation 1549:Category 1276:Frenulum 1200:Clitoris 1146:Frenulum 1063:External 1037:Fornices 722:Fimbriae 712:Ampullae 662:Oogonium 545:Albicans 495:Internal 380:21896560 217:In gene 1539:Anatomy 1369:Urethra 1332:Nerves 967:General 843:Isthmus 819:Regions 639:Medulla 562:Interna 557:Externa 513:Ovaries 371:3191938 58:Details 1525:Portal 1487:G-spot 1450:Veins 1360:Septum 1353:Fascia 1307:Veins 1272:Corona 1014:Vagina 974:Glands 885:Layers 848:Cervix 836:Fundus 831:Cavity 811:Uterus 707:Isthmi 670:Oocyte 632:Stroma 622:Cortex 552:Thecae 540:Luteum 530:Corpus 504:Adnexa 427:, and 419:(from 378:  368:  321:  270:TRIM28 266:CTNND1 170:sterol 123:oocyte 1480:Other 1268:Glans 1252:Angle 1218:Bulbs 1213:Crura 1185:Hymen 1173:Fossa 1081:Labia 1072:Vulva 1032:Walls 1027:Rugae 1022:Canal 875:Horns 853:Canal 727:Ostia 680:Ootid 605:Other 286:PTGS2 262:DHCR7 254:HSPB1 246:CXCR4 242:CCND2 231:PTGS2 227:GREM1 101:[ 90:18659 69:Latin 48:of a 1235:Body 1208:Root 893:Wall 826:Body 685:Ovum 394:link 376:PMID 319:ISBN 294:SCD5 292:and 290:SCD1 282:CX43 278:AREG 274:STAR 258:DVL3 250:GPX3 238:BDNF 229:and 223:HAS2 168:and 152:for 113:The 444:366 366:PMC 358:doi 296:. 214:. 85:FMA 50:cat 1551:: 431:) 429:UF 425:UB 423:, 421:UL 390:}} 386:{{ 374:. 364:. 354:17 352:. 348:. 333:^ 288:, 284:, 280:, 276:, 272:, 268:, 264:, 260:, 256:, 252:, 248:, 244:, 240:, 233:. 225:, 198:, 179:. 145:. 1527:: 479:e 472:t 465:v 396:) 382:. 360:: 327:. 117:( 105:] 20:)

Index

Discus proliger

ovarian follicle
cat
Latin
FMA
18659
Anatomical terminology
edit on Wikidata
oocyte
ovarian follicle
ovulation
antral follicle
membrana granulosa
corona radiata
spermatozoa
fertilization
amino acid transport
sterol
biosynthesis
gene transcription
in vitro fertilization
gene expression profiling
ovarian hyperstimulation
aneuploidy
embryo selection
expression profiling
HAS2
GREM1
PTGS2

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