524:(Matt Frewer): General practitioner, novelist, and TV medical expert, Mike is devoted to his patients, sometimes offering his services for free, much to the consternation of his partners in the practice. His many responsibilities sometimes plays havoc with his love life, as is exemplified in the pilot episode where his unhappy girlfriend has to resort to making a doctor's appointment to see him. The least willing to "maximize the practice," as Grant once suggested, Mike's greatest ambition is to be like
32:
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543:(Beau Gravitte): Accomplished, ambitious heart surgeon and the medical partner with whom Mike initially disagrees with the most, Grant is at times egocentric, vain and shallow with a taste for the finer things in life, though these qualities are later downplayed somewhat as the series progressed. He becomes a good friend of Mike's brother Richard.
537:): Mike's best friend and medical partner, an uptight, ambitious African-American who is anxious to have the “perfect life,” leading him to become at times overly controlling with his wife and son. Though at times exasperated by Mike's endless pranks and off-the-wall comments, Abe is usually the first to go out on a limb for his friend.
612:, a snobby blowhard and know-it-all, Hugh has a tendency to critique plays and novels without having any exposure to the material. He's constantly at odds with Mike during his segments, as it sometimes leads to on-air humiliation. It is later revealed that he is gay and HIV-positive, and he subsequently becomes a patient of Deirdre's.
426:. Most of the comedy surrounds Dr. Stratford's zany antics, tempered by his commitment to his profession and his patients. Though at first serving as "straight men" for Frewer's manic style of comic acting, the other characters gained more depth as the series progressed, and the plots sometimes focused on issues such as
563:): Mike's brother, and an English professor ("I'm an Associate Professor at a liberal arts college - they pay me in brie"), he shares a house with Mike. Having come out as gay, Richard maintains a close relationship with his brother, though Mike can't resist a good-natured jibe or two at his brother's expense.
549:(Maureen Mueller): The medical partner who comes off as aloof, or as she puts it, “a complete bitch,” and is not above exploiting a situation for her own benefit. However, she is very protective of her patients and her partners, especially Mike. Deirdre also has a weakness for the wrong men, like her
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only to promote his new novel. He soon found himself bickering with host Hugh
Persons during the live broadcast as it was plain to see that Hugh was attempting to fake his critique when he had never read the book. Producer Elizabeth McQueen liked his style (and that someone finally took the pompous
656:
Wanting to avoid the pitfalls of working in HMOs, the four decided to start a practice together after graduation. This decision initially led to conflicts as Mike's approach to medicine conflicted with his partners', particularly Grant's. The conflicts increased as he started a promotional campaign
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host down a peg or two), and offered him a spot on the show. Though Mike tries to cover serious medical issues in his segments on "Wake Up
Providence," they usually devolve into unplanned lunacy, which only endears him more to his viewers, and even raises the show's ratings, much to Hugh's dismay.
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Coming from a family of medical professionals, Mike
Stratford first befriended Abe Butterfield while attending Harvard Medical School. Aware of his need for a study group, Abe invited Mike to join his, where Mike met Grant Linowitz, Deirdre Bennett, and Peter Balcovske. At first, Mike got off to a
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bad start with the group with his apparent lack of preparation, and nervous habit of clowning around. Mike's medical skill was soon made evident when he quickly came to the aid of
Belkovske, the study group leader, who was having an epileptic attack and eventually dropped out of medical school.
642:): Mother to Mike and Richard, wife to Harold, an excellent nurse, Connie longs to return to her profession, even to the point where she works briefly with Mike as his nurse. Unfazed by Mike's goofy nature, she usually responds in kind, and is far more accepting of her son Richard being gay.
583:): Mike's sometime girlfriend, and television producer of "Wake Up Providence," Elizabeth tries to keep the show together as Mike presents one wacky medical segment after another. She leaves for New York after the episode, “Bachelor Doctor.”
573:): Psychiatrist and Grant's sister, Leona appears in the final season when she moves to Rhode Island with her daughter after her ex-husband writes a hit play which features a character based on her known only as "The Domineering Bitch"
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632:): Father to Mike and Richard, husband to Connie, Harold is a stuffy, well-established heart surgeon who disapproves of Mike's choice to be a general practitioner of medicine, as well as Richard's sexual orientation.
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410:, due to low ratings. One episode, "Long Day's Journey Into Deirdre", remains unaired in the United States (although it was aired as part of series runs in Australia and Great Britain).
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