223:
776:
51:
579:
526:
receptors, suggesting a role for dopamine in schizophrenia. Additional studies hypothesize dopamine dysregulation is involved in
Huntington's disease, ADHD, Tourette's syndrome, major depression, manic depression, addiction, hypertension and kidney dysfunction. Dopamine receptor antagonists are used
726:
First generation antipsychotics are used to treat schizophrenia and are often accompanied by extrapyramidal side effects. They inhibit dopaminergic neurotransmission in the brain by blocking about 72% of the D2 dopamine receptors. They can also block noradrenergic, cholinergic, and histaminergic
1215:
receptor and is used to treat schizophrenia, depression and bipolar disorder. There is controversy on whether
Ziprasidone treats negative symptoms and it has well documented gastrointestinal side effects. Ziprasidone can also cause
5614:
1065:. Clozapine is unique because it is only prescribed when treatment with at least two other antipsychotics has failed due to its very harsh side effects. It also requires weekly white blood cell counts to monitor potential
1136:
at high concentrations. It is used to treat the positive symptoms of schizophrenia, bipolar disorder and depression. Of the second generation antipsychotics, quetiapine may produce fewer parkinsonian side
1724:
Willis GL (2008). "Parkinson's disease as a neuroendocrine disorder of circadian function: dopamine-melatonin imbalance and the visual system in the genesis and progression of the degenerative process".
488:
are highly expressed on neurons in islands of
Calleja and nucleus accumbens shell and lowly expressed in areas such as the substantia nigra pars compacta, hippocampus, septal area, and ventral tegmental
522:
The dopaminergic system has been implicated in a variety of disorders. Parkinson's disease results from loss of dopaminergic neurons in the striatum. Furthermore, most effective antipsychotics block D
5607:
1114:
binds all receptors and is used to treat the positive and negative symptoms of schizophrenia as well as bipolar disorder and depression. It has been associated with significant weight gain.
1492:
Sokoloff P, Diaz J, Le Foll B, Guillin O, Leriche L, Bezard E, Gross C (February 2006). "The dopamine D3 receptor: a therapeutic target for the treatment of neuropsychiatric disorders".
5600:
2130:
2857:
95:
1019:
and is used to treat bipolar disorder and schizophrenia. Its side effects include weight gain but there is lower risk for orthostatic hypotension and hyperprolactinemia.
4651:
3395:
441:-like class, these receptors are found pre and post-synaptically. The genes that code these receptors have introns, leading to many alternately spliced variants.
467:
Peripherally, these receptors have been found in the renal, mesenteric, and splenic arteries as well as on the adrenal cortex and medulla and within the kidney.
349:
Peripherally, these receptors have been found in the renal artery, mesenteric artery, and splenic artery where activation leads to vasodilation. In addition, D
4912:
2850:
1779:
Young SL, Taylor M, Lawrie SM (April 2015). ""First do no harm." A systematic review of the prevalence and management of antipsychotic adverse effects".
1205:
and is used as an antipsychotic. It is also often used to treat dyskinesias, psychomotor agitations, tics, Huntington's chorea and alcohol dependence.
1001:
and is used as an antipsychotic, antidepressant and also treats bipolar disorder. It treats both the positive and negative symptoms of schizophrenia.
5366:
4868:
4832:
461:
are found in the striatum, substantia nigra, ventral tegmental area, hypothalamus, cortex, septum, amygdala, hippocampus, and olfactory tubercle.
4850:
4841:
2843:
2726:"A review of the discovery, pharmacological characterization, and behavioral effects of the dopamine D2-like receptor antagonist eticlopride"
5639:
5624:
2395:
986:
These drugs have fewer extrapyramidal side effects and are less likely to affect prolactin levels when compared to typical antipsychotics.
2483:
Pollack CV (July 2016). "Inhaled loxapine for the urgent treatment of acute agitation associated with schizophrenia or bipolar disorder".
513:
are found in amygdala, hippocampus, hypothalamus, globus pallidus, substantia nigra pars reticula, the thalamus, the retina and the kidney
1091:
Loxapine is often used to treat agitated and violent patients with neuropsychiatric disorders such as bipolar disorder and schizophrenia.
5947:
4859:
2656:
Stahl SM, Shayegan DK (2003). "The psychopharmacology of ziprasidone: receptor-binding properties and real-world psychiatric practice".
5519:
5463:
5172:
2685:"Review article: clinical implications of enteric and central D2 receptor blockade by antidopaminergic gastrointestinal prokinetics"
1038:
5356:
4905:
5538:
5452:
4241:
3272:
231:
5524:
4877:
701:
1191:
receptors. Risperidone not only treats the positive and negative symptoms of schizophrenia but also treats bipolar disorder.
2613:
Dose M, Lange HW (January 2000). "The benzamide tiapride: treatment of extrapyramidal motor and other clinical syndromes".
1233:
is a peripherally selective dopamine D2 receptor antagonist used as an antiemetic, gastroprokinetic agent and galactagogue.
6190:
5346:
5000:
4994:
599:β muscle spasms and sustained abnormal postures and onset occurs within a few days; can be treated with anticholinergics
6007:
5513:
5285:
4823:
1217:
966:
819:
5835:
5428:
5201:
4898:
20:
1560:
Missale C, Nash SR, Robinson SW, Jaber M, Caron MG (January 1998). "Dopamine receptors: from structure to function".
284:
are always found post-synaptically. The genes coding these receptors lack introns, so there are no splice variants.
6137:
5899:
5267:
5106:
5093:
5064:
5009:
4146:
3247:
6067:
5563:
5080:
592:
Early stage β occurs at onset of treatment or following increased dose, patients recover when dose is decreased
5457:
5403:
5388:
5360:
5141:
5136:
5127:
2829:
2527:
1681:
Zisapel N (December 2001). "Melatonin-dopamine interactions: from basic neurochemistry to a clinical setting".
1412:
Beaulieu JM, Gainetdinov RR (March 2011). "The physiology, signaling, and pharmacology of dopamine receptors".
691:
124:
3585:
5741:
5558:
5529:
5497:
5327:
5132:
5088:
5039:
4970:
3665:
633:
Late stage β occurs after prolonged (months-years) treatment, symptoms persist even after dose is decreased
586:
1982:
5751:
5439:
5245:
4051:
3227:
574:
555:
6057:
6028:
5652:
5592:
5570:
5414:
5147:
5034:
4397:
3671:
3338:
59:
1301:
and can be radiolabeled and used in PET imaging to identify disease progression in
Huntington's Disease
1033:
In addition, aripiprazole treats schizophrenia, bipolar disorder (mania), depression, and tic disorders
5781:
5575:
5419:
5272:
5225:
4646:
3857:
3128:
506:
481:
454:
368:
297:
4681:
3108:
2345:"Aripiprazole for the treatment of tic disorders in children: a systematic review and meta-analysis"
2254:
Stoner SC, Pace HA (May 2012). "Asenapine: a clinical review of a second-generation antipsychotic".
6074:
5719:
4984:
4786:
4062:
3519:
3329:
3158:
2961:
658:
192:
176:
168:
4756:
4012:
5982:
5816:
5423:
5392:
5123:
5019:
4621:
4448:
3359:
3253:
2869:
2638:
2508:
1804:
1750:
1706:
1663:
1620:
1437:
681:
636:
623:
due to effects on the nigrostriatal pathway - includes tremors, bradykinesia and muscle rigidity
172:
6164:
4298:
4257:
4207:
4152:
3143:
3123:
2940:
2825:
566:
They may include one or more of the following and last indefinitely even after cessation of the
3385:
6079:
6021:
5801:
5776:
5492:
5397:
5220:
5013:
4716:
4701:
4574:
3405:
2966:
2866:
2804:
2755:
2706:
2665:
2630:
2595:
2543:
2500:
2465:
2414:
2376:
2322:
2271:
2236:
2190:
2138:
2106:
2054:
2002:
1958:
1904:
1836:
1796:
1742:
1698:
1655:
1612:
1577:
1509:
1429:
743:
396:
380:
305:
222:
112:
107:
3645:
3087:
3033:
6062:
5937:
5876:
5811:
5694:
5482:
5276:
5191:
4945:
4776:
4696:
4564:
4172:
3987:
3596:
3429:
3038:
2877:
2794:
2786:
2745:
2737:
2696:
2622:
2585:
2577:
2535:
2492:
2455:
2445:
2406:
2366:
2356:
2312:
2302:
2263:
2226:
2180:
2172:
2096:
2088:
2044:
1994:
1948:
1940:
1894:
1884:
1788:
1734:
1690:
1647:
1604:
1569:
1501:
1421:
610:- pacing and restlessness and onset occurs within the first few months; can be treated with
551:
532:
430:
384:
309:
273:
243:
188:
79:
55:
24:
1929:"Pharmacology of the atypical antipsychotic remoxipride, a dopamine D2 receptor antagonist"
5972:
5410:
5322:
5160:
5155:
5025:
4989:
4979:
4962:
4247:
4237:
4217:
4087:
3997:
3268:
3218:
3183:
3178:
978:
These drugs are not only dopamine antagonists at the receptor specified, but also act on
6129:
6084:
5977:
5102:
4957:
4940:
4549:
4524:
4489:
4413:
4262:
3992:
3952:
3278:
3213:
2799:
2774:
2750:
2725:
2590:
2565:
2460:
2433:
2371:
2344:
2317:
2290:
2185:
2160:
2101:
2076:
1953:
1944:
1928:
1899:
1872:
1250:
749:
615:
325:
180:
234:, and are divided into two classes based on which G-protein they are coupled to. The D
6184:
5967:
5867:
5821:
5806:
5771:
5746:
5674:
5338:
5237:
5229:
5212:
5151:
4761:
4676:
4636:
4509:
4328:
4252:
4212:
4192:
4092:
3837:
3686:
3681:
3624:
3575:
3504:
3309:
3071:
3007:
2741:
2701:
2684:
2642:
1738:
1244:
528:
392:
184:
100:
75:
2267:
1754:
1710:
1667:
1624:
5942:
5761:
5699:
5684:
5628:
5317:
5183:
5166:
4921:
4771:
4766:
4751:
4671:
4631:
4605:
4600:
4559:
4554:
4403:
4348:
4338:
4303:
4293:
4222:
4182:
4142:
4102:
4077:
4067:
4057:
4007:
3982:
3977:
3947:
3902:
3706:
3701:
3661:
3514:
3344:
3324:
3314:
3258:
3243:
3233:
3148:
2683:
Tonini M, Cipollina L, Poluzzi E, Crema F, Corazza GR, De Ponti F (February 2004).
2539:
2512:
2410:
2176:
1808:
1441:
1140:
1022:
942:
884:
869:
825:
784:
705:
620:
611:
376:
332:
321:
2496:
1983:"Effects of antipsychotic medications on appetite, weight, and insulin resistance"
1573:
2037:"How do we choose between atypical antipsychotics? The advantages of amisulpride"
1827:
Arana GW (2000). "An overview of side effects caused by typical antipsychotics".
130:
6147:
6124:
6045:
6002:
5997:
5962:
5891:
5845:
5791:
5786:
5766:
5756:
5709:
5474:
5447:
5380:
5073:
4953:
4736:
4721:
4706:
4569:
4539:
4534:
4529:
4499:
4473:
4468:
4463:
4438:
4433:
4418:
4408:
4388:
4383:
4368:
4358:
4353:
4343:
4323:
4308:
4288:
4273:
4227:
4162:
4137:
4127:
4122:
4117:
4072:
4047:
4017:
3967:
3927:
3872:
3867:
3847:
3812:
3797:
3787:
3777:
3757:
3747:
3691:
3606:
3529:
3524:
3509:
3462:
3369:
3364:
3354:
3319:
3294:
3263:
3223:
3103:
3048:
3022:
3012:
2951:
1277:
1263:
1230:
1208:
1176:
1166:
1094:
1066:
990:
874:
847:
795:
388:
344:
203:
2835:
2231:
2214:
1651:
1595:
Seeman P (August 2006). "Targeting the dopamine D2 receptor in schizophrenia".
1505:
6159:
6119:
6114:
6109:
6094:
5992:
5957:
5952:
5932:
5855:
5850:
5704:
5689:
5679:
5300:
5115:
4741:
4731:
4726:
4711:
4666:
4661:
4590:
4519:
4514:
4504:
4458:
4453:
4443:
4428:
4423:
4393:
4363:
4333:
4313:
4232:
4202:
4042:
4037:
4032:
4027:
4022:
4002:
3972:
3962:
3922:
3917:
3912:
3907:
3892:
3877:
3832:
3827:
3822:
3817:
3782:
3772:
3767:
3752:
3676:
3640:
3601:
3580:
3534:
3488:
3452:
3400:
3349:
3334:
3299:
3208:
3138:
3133:
3118:
3113:
3066:
3043:
3017:
3002:
2956:
2930:
2925:
2920:
2915:
2910:
2905:
2790:
2581:
2450:
2361:
2049:
2036:
1998:
1694:
1608:
1290:
1236:
1117:
1111:
789:
731:
668:
340:
199:
41:
2092:
1792:
6169:
6152:
5987:
5909:
5886:
5731:
5669:
5309:
5259:
4801:
4781:
4746:
4691:
4686:
4641:
4595:
4585:
4378:
4373:
4318:
4278:
4197:
4187:
4177:
4167:
4082:
3957:
3897:
3887:
3862:
3852:
3842:
3802:
3742:
3737:
3656:
3611:
3554:
3549:
3483:
3478:
3473:
3457:
3415:
3410:
3304:
3289:
3188:
3153:
3053:
2981:
2976:
1046:
1004:
979:
928:
907:
775:
739:
607:
547:
2808:
2759:
2710:
2669:
2634:
2599:
2547:
2504:
2469:
2418:
2380:
2326:
2275:
2240:
2194:
2142:
2110:
2058:
2006:
1962:
1908:
1840:
1800:
1746:
1702:
1659:
1616:
1513:
1433:
578:
1889:
1581:
1425:
665:
receptors in the anterior pituitary leading to increased prolactin release
649:
It is hypothesized that these effects are due to chronic blockade of the D
6040:
5927:
5736:
5350:
4791:
4626:
4544:
4478:
4157:
4132:
4107:
4097:
3807:
3792:
3722:
3632:
3570:
3565:
3539:
3390:
3374:
3238:
3079:
2971:
2935:
2900:
1194:
1072:
965:
at higher concentrations
Thioridazine has the highest associated risk of
889:
879:
696:
596:
567:
540:
336:
317:
313:
211:
196:
87:
2626:
1638:
Iversen SD, Iversen LL (May 2007). "Dopamine: 50 years in perspective".
492:
Additional studies have found these receptors peripherally in the kidney
143:
50:
5796:
4974:
4656:
4494:
4283:
4112:
3882:
3732:
3727:
3696:
3098:
2997:
2992:
2307:
687:
675:
464:
These receptors have also been found in the retina and pituitary gland.
1037:
183:
are dopamine antagonists, and as such they have found use in treating
5487:
5056:
4936:
4890:
4796:
3762:
3616:
3493:
3058:
2215:"QTc prolongation, torsades de pointes, and psychotropic medications"
1873:"Second-generation antipsychotics and extrapyramidal adverse effects"
671:
including increased craving and binge eating that lead to weight gain
536:
207:
83:
554:
functions, although pathological imbalances have been implicated in
2528:"Quetiapine versus other atypical antipsychotics for schizophrenia"
4616:
3717:
1036:
774:
577:
221:
5596:
4894:
2839:
2289:
Scheidemantel T, Korobkova I, Rej S, Sajatovic M (2015-12-04).
3544:
570:
antagonist, especially after long-term or high-dosage use:
2779:
European
Journal of Nuclear Medicine and Molecular Imaging
2566:"Comparative Pharmacology of Risperidone and Paliperidone"
779:
Chemical
Structure of typical antipsychotic chlorpromazine
2775:"Current status of PET imaging in Huntington's disease"
2343:
Yang CS, Huang H, Zhang LL, Zhu CR, Guo Q (July 2015).
639:- includes involuntary and repetitive facial movements
2559:
2557:
2396:"Aripiprazole alone or in combination for acute mania"
1871:
Divac N, Prostran M, Jakovcevski I, Cerovac N (2014).
1225:
Dopamine antagonists used to treat nausea and vomiting
1987:
Endocrinology and
Metabolism Clinics of North America
742:
receptors. It is absorbed very easily and has a high
2041:
6093:
6020:
5920:
5864:
5834:
5718:
5660:
5651:
5636:
5551:
5506:
5473:
5438:
5379:
5337:
5308:
5299:
5258:
5211:
5182:
5114:
5101:
5087:
5072:
5055:
5048:
4928:
3936:
3441:
3428:
3197:
3167:
2889:
2876:
602:
risk factors include age, gender and family history
137:
123:
118:
106:
94:
71:
66:
32:
238:-like class of dopamine receptors is coupled to GΞ±
2030:
2028:
2026:
2024:
2022:
2020:
2018:
2016:
1487:
1485:
1483:
1481:
1479:
1477:
1475:
1473:
1471:
1407:
1405:
1403:
1401:
1399:
1397:
1395:
1393:
1391:
1389:
1387:
1385:
1383:
1381:
1379:
1377:
1375:
1373:
1371:
1369:
1367:
1365:
1363:
1361:
1359:
1357:
1355:
1353:
1351:
1349:
1347:
1345:
1343:
1341:
1339:
1337:
1335:
1555:
1553:
1551:
1549:
1547:
1545:
1543:
1469:
1467:
1465:
1463:
1461:
1459:
1457:
1455:
1453:
1451:
1333:
1331:
1329:
1327:
1325:
1323:
1321:
1319:
1317:
1315:
254:and thus inhibits adenylate cyclase production.
1541:
1539:
1537:
1535:
1533:
1531:
1529:
1527:
1525:
1523:
704:is a medical emergency caused by a decrease in
550:suppresses dopamine activity as part of normal
2773:Pagano G, Niccolini F, Politis M (June 2016).
2394:Brown R, Taylor MJ, Geddes J (December 2013).
2154:
2152:
1922:
1920:
1918:
589:(EPS) associated with typical antipsychotics:
5608:
4906:
2851:
1866:
1864:
1862:
1860:
1858:
1856:
1854:
1852:
1850:
1494:CNS & Neurological Disorders Drug Targets
8:
3597:Deoxyepinephrine (N-methyldopamine, epinine)
3039:Deoxyepinephrine (N-methyldopamine, epinine)
2338:
2336:
1822:
1820:
1818:
1774:
1772:
1770:
1768:
1766:
1764:
2403:The Cochrane Database of Systematic Reviews
2165:The Cochrane Database of Systematic Reviews
1976:
1974:
1972:
1057:with the highest affinity but still binds D
974:Second-generation antipsychotics (atypical)
810:with the highest affinity, but also binds D
792:is used as an antipsychotic and antiemetic.
756:with the highest affinity, but also binds D
5657:
5648:
5615:
5601:
5593:
5305:
5111:
5098:
5052:
4913:
4899:
4891:
3438:
2886:
2858:
2844:
2836:
2689:Alimentary Pharmacology & Therapeutics
2434:"Revisiting loxapine: a systematic review"
1258:Antagonists used only in research settings
49:
2828:at the U.S. National Library of Medicine
2798:
2749:
2700:
2589:
2459:
2449:
2432:Popovic D, Nuss P, Vieta E (2015-04-01).
2370:
2360:
2316:
2306:
2230:
2184:
2100:
2048:
1952:
1898:
1888:
722:First-generation antipsychotics (typical)
686:Metabolic changes with increased risk of
642:risk factors include age, race and gender
4486:Antiemetics/gastroprokinetics/sedatives
2532:Cochrane Database of Systematic Reviews
1311:
1173:receptors with relatively low affinity.
406:receptors have been found in the kidney
353:receptors have been found in the kidney
2295:Neuropsychiatric Disease and Treatment
2129:Chokhawala, Krutika (2 October 2021).
1029:as a partial agonist but antagonizes D
939:and is also used as an antidepressant.
866:and is also used as an antidepressant.
29:
5625:functional gastrointestinal disorders
2219:The Academy of Psychosomatic Medicine
2208:
2206:
2204:
2124:
2122:
2120:
2070:
2068:
1597:Expert Opinion on Therapeutic Targets
7:
2485:Current Medical Research and Opinion
1274:with high affinity but also binds D4
331:Also found (in lower levels) in the
16:Drug which blocks dopamine receptors
5948:Dimethylaminopropionylphenothiazine
4088:Levomepromazine (methotrimeprazine)
2730:CNS Neuroscience & Therapeutics
1683:Cellular and Molecular Neurobiology
1155:with high affinity; can also bind D
1087:with high affinity; can also bind D
957:with high affinity; can also bind D
922:with high affinity; can also bind D
626:risk factors include age and gender
304:are found mainly on neurons in the
5520:Angiotensin II receptor antagonist
5464:Endocannabinoid reuptake inhibitor
2658:The Journal of Clinical Psychiatry
2159:Leucht S, Hartung B (April 2005).
1945:10.1111/j.1527-3458.2001.tb00199.x
1835:(Suppl 8): 5β11, discussion 12β3.
1829:The Journal of Clinical Psychiatry
708:activity, resulting in a central D
387:; as well as memory areas such as
14:
5411:Acetylcholine receptor antagonist
5173:Norepinephrine reuptake inhibitor
2742:10.1111/j.1755-5949.2008.00047.x
2702:10.1111/j.1365-2036.2004.01867.x
2291:"Asenapine for bipolar disorder"
2077:"Neuroleptic Malignant Syndrome"
1739:10.1515/revneuro.2008.19.4-5.245
900:with high affinity, also binds D
818:Haloperidol also has a risk for
5539:Vasopressin receptor antagonist
5453:Cannabinoid receptor antagonist
4869:Monoamine metabolism modulators
2268:10.1016/j.clinthera.2012.03.002
836:with the highest affinity but D
6104:Primarily dopamine antagonists
6053:Quaternary ammonium compounds:
5525:Endothelin receptor antagonist
5389:Acetylcholine receptor agonist
5148:Adrenergic receptor antagonist
2724:Martelle JL, Nader MA (2008).
2540:10.1002/14651858.CD006625.pub3
2411:10.1002/14651858.CD005000.pub2
2177:10.1002/14651858.CD003083.pub2
2161:"Benperidol for schizophrenia"
2075:Berman, Brian (January 2011).
702:Neuroleptic Malignant Syndrome
1:
5357:Glutamate receptor antagonist
5273:Serotonin receptor antagonist
5226:Histamine receptor antagonist
5001:Negative allosteric modulator
4995:Positive allosteric modulator
4851:Monoamine reuptake inhibitors
4824:Receptor/signaling modulators
3003:Adrogolide (ABT-431, DAS-431)
2564:Corena-McLeod M (June 2015).
2497:10.1185/03007995.2016.1170004
1877:BioMed Research International
1781:Journal of Psychopharmacology
1574:10.1152/physrev.1998.78.1.189
6008:Trimethyldiphenylpropylamine
5514:Adenosine reuptake inhibitor
5448:Cannabinoid receptor agonist
5367:Glutamate reuptake inhibitor
5286:Serotonin reuptake inhibitor
5197:Dopamine receptor antagonist
2438:Annals of General Psychiatry
1727:Reviews in the Neurosciences
250:-like class is coupled to GΞ±
226:Dopamine receptor flow chart
161:dopamine receptor antagonist
33:Dopamine receptor antagonist
5202:Dopamine reuptake inhibitor
5124:Adrenergic receptor agonist
2131:"Antipsychotic Medications"
232:G proteinβcoupled receptors
230:Dopamine receptors are all
56:Skeletal structural formula
21:dopamine reuptake inhibitor
6207:
5493:Opioid receptor antagonist
5347:Glutamate receptor agonist
5268:Serotonin receptor agonist
5221:Histamine receptor agonist
4860:Monoamine releasing agents
4048:Flupentixol (flupenthixol)
3224:Flupentixol (flupenthixol)
2232:10.1016/j.psym.2012.11.001
2035:Mortimer AM (March 2004).
1652:10.1016/j.tins.2007.03.002
1506:10.2174/187152706784111551
1243:receptors and also treats
527:for some diseases such as
18:
5192:Dopamine receptor agonist
4814:
4712:Metitepine (methiothepin)
4138:Pericyazine (periciazine)
3562:Dihydrexidine derivatives
3401:Metitepine (methiothepin)
2989:Dihydrexidine derivatives
2791:10.1007/s00259-016-3324-6
2582:10.1007/s40268-015-0092-x
2451:10.1186/s12991-015-0053-3
2362:10.1186/s12888-015-0504-z
2050:10.1017/S1461145704004134
1999:10.1016/j.ecl.2013.05.006
1981:Deng C (September 2013).
1609:10.1517/14728222.10.4.515
1253:also treats gastroparesis
246:production, whereas the D
206:used in the treatment of
142:
48:
39:
5458:Endocannabinoid enhancer
5404:Cholinesterase inhibitor
5323:GABA receptor antagonist
4314:Clotiapine (clothiapine)
4188:Spiperone (spiroperidol)
4153:Piflutixol (pifluthixol)
2830:Medical Subject Headings
2093:10.1177/1941875210386491
2043:. 7 Suppl 1 (5): S21-5.
1793:10.1177/0269881114562090
692:diabetes mellitus type 2
661:due to blockade of the D
19:Not to be confused with
5498:Enkephalinase inhibitor
5488:Opioid receptor agonist
5328:GABA reuptake inhibitor
5033:♦ Miscellaneous:
4270:Atypical antipsychotics
3653:Atypical antipsychotics
3586:N,N-Propyldihydrexidine
3286:Atypical antipsychotics
3175:Tetrahydroisoquinolines
1695:10.1023/A:1015187601628
1640:Trends in Neurosciences
1414:Pharmacological Reviews
587:Extrapyramidal symptoms
518:Implications in disease
375:have been found in the
5081:Ion channel modulators
3944:Typical antipsychotics
3205:Typical antipsychotics
2081:The Neuro Hospitalists
1042:
780:
582:
575:Cardiovascular disease
227:
5318:GABA receptor agonist
4878:Monoamine neurotoxins
3672:Aripiprazole lauroxil
2526:Asmal, Laila (2013).
2256:Clinical Therapeutics
2213:Beach, Scott (2013).
1562:Physiological Reviews
1426:10.1124/pr.110.002642
1040:
778:
581:
225:
218:Receptor pharmacology
60:typical antipsychotic
35:Dopaminergic blockers
6191:Dopamine antagonists
4647:Desmethoxyfallypride
3858:Propylnorapomorphine
3657:Alentemol (U-66444B)
3129:Propylnorapomorphine
2826:Dopamine+antagonists
6075:Cimetropium bromide
5868:serotonin receptors
5534:receptor antagonist
4787:Tetrahydropalmatine
3520:Dihydroergocryptine
3159:Tetrahydropalmatine
2962:Dihydroergocryptine
2627:10.1055/s-2000-7964
1890:10.1155/2014/656370
969:among neuroleptics.
674:Increased risk for
659:Hyperprolactinaemia
556:Parkinson's disease
193:stimulant psychosis
177:receptor antagonism
155:, also known as an
153:dopamine antagonist
5983:Pinaverium bromide
4922:Pharmacomodulation
2664:(Suppl 19): 6β12.
2615:Pharmacopsychiatry
2308:10.2147/NDT.S78043
1043:
781:
712:receptor blockade.
682:Sexual dysfunction
669:Increased appetite
637:Tardive dyskinesia
583:
415:-like receptors: D
262:-like receptors: D
228:
173:dopamine receptors
113:Dopamine receptors
58:of Haloperidol, a
6178:
6177:
6080:Fentonium bromide
6068:Methylscopolamine
6016:
6015:
5836:Phosphodiesterase
5830:
5829:
5590:
5589:
5586:
5585:
5547:
5546:
5375:
5374:
5295:
5294:
5065:Enzyme inhibition
4888:
4887:
4881:
4872:
4863:
4854:
4845:
4836:
4827:
4810:
4809:
4717:N-Methylspiperone
4575:Trimethobenzamide
3635:
3627:
3619:
3424:
3423:
3082:
3074:
3061:
2867:Dopamine receptor
2145:– via NCBI.
744:first pass effect
397:entorhinal cortex
381:prefrontal cortex
306:nucleus accumbens
274:D1-like receptors
244:adenylate cyclase
157:anti-dopaminergic
149:
148:
108:Biological target
67:Class identifiers
6198:
6063:Butylscopolamine
6038:Tertiary amines:
5938:Chlorbenzoxamine
5695:Oxyphencyclimine
5658:
5649:
5617:
5610:
5603:
5594:
5564:Enzyme cofactors
5483:Opioid modulator
5440:Cannabinoidergic
5306:
5112:
5099:
5053:
4915:
4908:
4901:
4892:
4875:
4866:
4857:
4848:
4839:
4830:
4818:
4697:Levofenfluramine
4565:Thiethylperazine
4242:+tranylcypromine
4173:Prochlorperazine
3988:Chlorproethazine
3633:
3625:
3620:-DOPA (levodopa)
3617:
3439:
3273:+tranylcypromine
3080:
3072:
3062:-DOPA (levodopa)
3059:
2887:
2860:
2853:
2846:
2837:
2813:
2812:
2802:
2770:
2764:
2763:
2753:
2721:
2715:
2714:
2704:
2680:
2674:
2673:
2653:
2647:
2646:
2610:
2604:
2603:
2593:
2570:Drugs in R&D
2561:
2552:
2551:
2534:(11): CD006625.
2523:
2517:
2516:
2480:
2474:
2473:
2463:
2453:
2429:
2423:
2422:
2405:(12): CD005000.
2400:
2391:
2385:
2384:
2374:
2364:
2340:
2331:
2330:
2320:
2310:
2286:
2280:
2279:
2251:
2245:
2244:
2234:
2210:
2199:
2198:
2188:
2156:
2147:
2146:
2126:
2115:
2114:
2104:
2072:
2063:
2062:
2052:
2032:
2011:
2010:
1978:
1967:
1966:
1956:
1933:CNS Drug Reviews
1927:Nadal R (2001).
1924:
1913:
1912:
1902:
1892:
1868:
1845:
1844:
1824:
1813:
1812:
1776:
1759:
1758:
1733:(4β5): 245β316.
1721:
1715:
1714:
1678:
1672:
1671:
1635:
1629:
1628:
1592:
1586:
1585:
1557:
1518:
1517:
1489:
1446:
1445:
1409:
1218:QTc prolongation
967:QTc prolongation
820:QTc prolongation
552:circadian rhythm
533:bipolar disorder
385:cingulate cortex
310:substantia nigra
195:. Several other
189:bipolar disorder
167:), is a type of
133:
80:bipolar disorder
53:
30:
25:dopamine agonist
6206:
6205:
6201:
6200:
6199:
6197:
6196:
6195:
6181:
6180:
6179:
6174:
6141:
6089:
6029:antimuscarinics
6026:
6025:and derivatives
6024:
6012:
5973:Mentha piperita
5916:
5903:
5880:
5866:
5860:
5837:
5826:
5724:
5721:
5714:
5662:
5653:Antimuscarinics
5643:
5641:
5638:
5632:
5621:
5591:
5582:
5543:
5533:
5502:
5469:
5434:
5371:
5333:
5291:
5280:
5254:
5249:
5241:
5233:
5207:
5178:
5092:
5083:
5068:
5044:
4990:Inverse agonist
4980:Partial agonist
4924:
4919:
4889:
4884:
4806:
4582:Antidepressants
4248:Triflupromazine
4238:Trifluoperazine
4218:Thioproperazine
3998:Chlorprothixene
3932:
3593:Phenethylamines
3433:
3420:
3269:Trifluoperazine
3219:Chlorprothixene
3193:
3163:
3030:Phenethylamines
2881:
2872:
2864:
2822:
2817:
2816:
2772:
2771:
2767:
2723:
2722:
2718:
2682:
2681:
2677:
2655:
2654:
2650:
2612:
2611:
2607:
2563:
2562:
2555:
2525:
2524:
2520:
2482:
2481:
2477:
2431:
2430:
2426:
2398:
2393:
2392:
2388:
2342:
2341:
2334:
2288:
2287:
2283:
2253:
2252:
2248:
2212:
2211:
2202:
2171:(2): CD003083.
2158:
2157:
2150:
2128:
2127:
2118:
2074:
2073:
2066:
2034:
2033:
2014:
1980:
1979:
1970:
1926:
1925:
1916:
1870:
1869:
1848:
1826:
1825:
1816:
1778:
1777:
1762:
1723:
1722:
1718:
1680:
1679:
1675:
1637:
1636:
1632:
1594:
1593:
1589:
1559:
1558:
1521:
1491:
1490:
1449:
1411:
1410:
1313:
1308:
1300:
1296:
1287:
1283:
1273:
1269:
1260:
1242:
1239:binds enteric D
1227:
1214:
1204:
1200:
1190:
1186:
1182:
1172:
1162:
1158:
1154:
1150:
1146:
1135:
1131:
1127:
1123:
1108:
1104:
1100:
1090:
1086:
1082:
1078:
1064:
1060:
1056:
1052:
1032:
1028:
1018:
1014:
1010:
1000:
996:
985:
976:
964:
960:
956:
952:
948:
938:
934:
925:
921:
917:
913:
903:
899:
895:
865:
861:
857:
853:
843:
839:
835:
831:
817:
813:
809:
805:
801:
771:
767:
763:
759:
755:
737:
724:
719:
711:
664:
652:
616:benzodiazepines
564:
525:
520:
510:
503:
500:
485:
478:
475:
458:
451:
448:
440:
435:-like receptors
434:
428:
426:
422:
418:
414:
405:
372:
364:
361:
352:
301:
294:
291:
283:
279:
271:
269:
265:
261:
253:
249:
242:and stimulates
241:
237:
220:
129:
62:
34:
28:
17:
12:
11:
5:
6204:
6202:
6194:
6193:
6183:
6182:
6176:
6175:
6173:
6172:
6167:
6162:
6157:
6156:
6155:
6150:
6139:
6134:
6133:
6132:
6130:Metoclopramide
6127:
6122:
6117:
6112:
6099:
6097:
6091:
6090:
6088:
6087:
6085:Methylatropine
6082:
6077:
6072:
6071:
6070:
6065:
6060:
6049:
6048:
6043:
6034:
6032:
6018:
6017:
6014:
6013:
6011:
6010:
6005:
6000:
5995:
5990:
5985:
5980:
5978:Phloroglucinol
5975:
5970:
5965:
5960:
5955:
5950:
5945:
5940:
5935:
5930:
5924:
5922:
5918:
5917:
5915:
5914:
5913:
5912:
5901:
5896:
5895:
5894:
5889:
5878:
5872:
5870:
5862:
5861:
5859:
5858:
5853:
5848:
5842:
5840:
5832:
5831:
5828:
5827:
5825:
5824:
5819:
5814:
5809:
5804:
5799:
5794:
5789:
5784:
5779:
5774:
5769:
5764:
5759:
5754:
5752:Glycopyrronium
5749:
5744:
5739:
5734:
5728:
5726:
5716:
5715:
5713:
5712:
5707:
5702:
5697:
5692:
5687:
5682:
5677:
5672:
5666:
5664:
5655:
5646:
5634:
5633:
5622:
5620:
5619:
5612:
5605:
5597:
5588:
5587:
5584:
5583:
5581:
5580:
5568:
5555:
5553:
5549:
5548:
5545:
5544:
5542:
5541:
5536:
5531:
5527:
5522:
5517:
5510:
5508:
5504:
5503:
5501:
5500:
5495:
5490:
5485:
5479:
5477:
5471:
5470:
5468:
5467:
5461:
5455:
5450:
5444:
5442:
5436:
5435:
5433:
5432:
5426:
5417:
5408:
5407:
5406:
5395:
5385:
5383:
5377:
5376:
5373:
5372:
5370:
5369:
5364:
5354:
5343:
5341:
5335:
5334:
5332:
5331:
5325:
5320:
5314:
5312:
5303:
5297:
5296:
5293:
5292:
5290:
5289:
5283:
5278:
5270:
5264:
5262:
5256:
5255:
5253:
5252:
5247:
5243:
5239:
5235:
5231:
5223:
5217:
5215:
5209:
5208:
5206:
5205:
5199:
5194:
5188:
5186:
5180:
5179:
5177:
5176:
5170:
5164:
5158:
5145:
5139:
5130:
5120:
5118:
5109:
5096:
5085:
5084:
5078:
5076:
5070:
5069:
5061:
5059:
5050:
5046:
5045:
5043:
5042:
5037:
5030:
5029:
5023:
5017:
5005:
5004:
4998:
4992:
4987:
4982:
4977:
4966:
4965:
4960:
4949:
4948:
4943:
4932:
4930:
4926:
4925:
4920:
4918:
4917:
4910:
4903:
4895:
4886:
4885:
4883:
4882:
4873:
4864:
4855:
4846:
4837:
4828:
4815:
4812:
4811:
4808:
4807:
4805:
4804:
4799:
4794:
4789:
4784:
4779:
4774:
4769:
4764:
4759:
4754:
4749:
4744:
4739:
4734:
4729:
4724:
4719:
4714:
4709:
4704:
4699:
4694:
4689:
4684:
4682:Isocorypalmine
4679:
4674:
4669:
4664:
4659:
4654:
4649:
4644:
4639:
4634:
4629:
4624:
4619:
4609:
4608:
4603:
4598:
4593:
4588:
4578:
4577:
4572:
4567:
4562:
4557:
4552:
4550:Metoclopramide
4547:
4542:
4537:
4532:
4527:
4525:Deudomperidone
4522:
4517:
4512:
4507:
4502:
4497:
4492:
4490:Aceprometazine
4482:
4481:
4476:
4471:
4466:
4461:
4456:
4451:
4446:
4441:
4436:
4431:
4426:
4421:
4416:
4414:Piperacetazine
4411:
4406:
4401:
4391:
4386:
4381:
4376:
4371:
4366:
4361:
4356:
4351:
4346:
4341:
4336:
4331:
4326:
4321:
4316:
4311:
4306:
4301:
4296:
4291:
4286:
4281:
4276:
4266:
4265:
4263:Zuclopenthixol
4260:
4255:
4250:
4245:
4235:
4230:
4225:
4220:
4215:
4210:
4205:
4200:
4195:
4190:
4185:
4180:
4175:
4170:
4165:
4160:
4155:
4150:
4147:+amitriptyline
4140:
4135:
4130:
4125:
4120:
4115:
4110:
4105:
4100:
4095:
4090:
4085:
4080:
4075:
4070:
4065:
4060:
4055:
4045:
4040:
4035:
4030:
4025:
4020:
4015:
4010:
4005:
4000:
3995:
3993:Chlorpromazine
3990:
3985:
3980:
3975:
3970:
3965:
3960:
3955:
3953:Acetophenazine
3950:
3940:
3938:
3934:
3933:
3931:
3930:
3925:
3920:
3915:
3910:
3905:
3900:
3895:
3890:
3885:
3880:
3875:
3870:
3865:
3860:
3855:
3850:
3845:
3840:
3835:
3830:
3825:
3820:
3815:
3810:
3805:
3800:
3795:
3790:
3785:
3780:
3775:
3770:
3765:
3760:
3755:
3750:
3745:
3740:
3735:
3730:
3725:
3720:
3710:
3709:
3704:
3699:
3694:
3689:
3684:
3679:
3674:
3669:
3659:
3649:
3648:
3643:
3638:
3630:
3628:-Phenylalanine
3622:
3614:
3609:
3604:
3599:
3589:
3588:
3583:
3578:
3573:
3568:
3558:
3557:
3552:
3547:
3542:
3537:
3532:
3527:
3522:
3517:
3512:
3507:
3497:
3496:
3491:
3486:
3481:
3476:
3470:Aminotetralins
3466:
3465:
3460:
3455:
3445:
3443:
3436:
3431:
3426:
3425:
3422:
3421:
3419:
3418:
3413:
3408:
3403:
3398:
3393:
3388:
3378:
3377:
3372:
3367:
3362:
3357:
3352:
3347:
3342:
3332:
3327:
3322:
3317:
3312:
3307:
3302:
3297:
3292:
3282:
3281:
3279:Zuclopenthixol
3276:
3266:
3261:
3256:
3251:
3248:+amitriptyline
3241:
3236:
3231:
3221:
3216:
3214:Chlorpromazine
3211:
3201:
3199:
3195:
3194:
3192:
3191:
3186:
3181:
3171:
3169:
3165:
3164:
3162:
3161:
3156:
3151:
3146:
3141:
3136:
3131:
3126:
3121:
3116:
3111:
3109:Isocorypalmine
3106:
3101:
3091:
3090:
3085:
3077:
3075:-Phenylalanine
3069:
3064:
3056:
3051:
3046:
3041:
3036:
3026:
3025:
3020:
3015:
3010:
3005:
3000:
2995:
2985:
2984:
2979:
2974:
2969:
2964:
2959:
2954:
2944:
2943:
2938:
2933:
2928:
2923:
2918:
2913:
2908:
2903:
2893:
2891:
2884:
2879:
2874:
2873:
2865:
2863:
2862:
2855:
2848:
2840:
2834:
2833:
2821:
2820:External links
2818:
2815:
2814:
2785:(6): 1171β82.
2765:
2716:
2675:
2648:
2605:
2553:
2518:
2491:(7): 1253β60.
2475:
2424:
2386:
2349:BMC Psychiatry
2332:
2281:
2262:(5): 1023β40.
2246:
2200:
2148:
2116:
2064:
2012:
1968:
1914:
1846:
1814:
1760:
1716:
1673:
1630:
1587:
1568:(1): 189β225.
1519:
1447:
1420:(1): 182β217.
1310:
1309:
1307:
1304:
1303:
1302:
1298:
1294:
1288:
1285:
1281:
1275:
1271:
1267:
1259:
1256:
1255:
1254:
1251:Metoclopramide
1248:
1240:
1234:
1226:
1223:
1222:
1221:
1212:
1206:
1202:
1198:
1192:
1188:
1184:
1180:
1174:
1170:
1164:
1160:
1156:
1152:
1148:
1144:
1138:
1133:
1132:and can bind D
1129:
1125:
1121:
1115:
1109:
1106:
1102:
1098:
1092:
1088:
1084:
1080:
1076:
1070:
1062:
1058:
1054:
1050:
1035:
1034:
1030:
1026:
1020:
1016:
1012:
1008:
1002:
998:
994:
983:
975:
972:
971:
970:
962:
958:
954:
950:
946:
940:
936:
932:
926:
923:
919:
915:
911:
905:
901:
897:
893:
887:
882:
877:
872:
867:
863:
859:
855:
851:
845:
841:
837:
833:
829:
823:
815:
811:
807:
803:
799:
793:
787:
773:
772:
769:
765:
761:
757:
753:
750:Chlorpromazine
747:
735:
723:
720:
718:
715:
714:
713:
709:
699:
694:
684:
679:
672:
666:
662:
656:
655:
654:
650:
647:
646:
645:
644:
643:
631:
630:
629:
628:
627:
618:
605:
604:
603:
584:
563:
560:
559:
558:
523:
519:
516:
515:
514:
508:
502:
498:
495:
494:
493:
490:
483:
477:
473:
470:
469:
468:
465:
462:
456:
450:
446:
443:
438:
432:
427:
424:
420:
416:
412:
409:
408:
407:
403:
402:In addition, D
400:
370:
367:Low levels of
363:
359:
356:
355:
354:
350:
347:
329:
326:olfactory bulb
322:frontal cortex
299:
293:
289:
286:
281:
277:
270:
267:
263:
259:
256:
251:
247:
239:
235:
219:
216:
181:antipsychotics
147:
146:
140:
139:
135:
134:
127:
121:
120:
119:External links
116:
115:
110:
104:
103:
98:
92:
91:
73:
69:
68:
64:
63:
54:
46:
45:
37:
36:
15:
13:
10:
9:
6:
4:
3:
2:
6203:
6192:
6189:
6188:
6186:
6171:
6168:
6166:
6163:
6161:
6158:
6154:
6151:
6149:
6146:
6145:
6144:
6143:
6135:
6131:
6128:
6126:
6123:
6121:
6118:
6116:
6113:
6111:
6108:
6107:
6106:
6105:
6101:
6100:
6098:
6096:
6092:
6086:
6083:
6081:
6078:
6076:
6073:
6069:
6066:
6064:
6061:
6059:
6056:
6055:
6054:
6051:
6050:
6047:
6044:
6042:
6039:
6036:
6035:
6033:
6030:
6023:
6019:
6009:
6006:
6004:
6001:
5999:
5996:
5994:
5991:
5989:
5986:
5984:
5981:
5979:
5976:
5974:
5971:
5969:
5968:Isometheptene
5966:
5964:
5961:
5959:
5956:
5954:
5951:
5949:
5946:
5944:
5941:
5939:
5936:
5934:
5931:
5929:
5926:
5925:
5923:
5919:
5911:
5908:
5907:
5906:
5905:
5897:
5893:
5890:
5888:
5885:
5884:
5883:
5882:
5874:
5873:
5871:
5869:
5863:
5857:
5854:
5852:
5849:
5847:
5844:
5843:
5841:
5839:
5833:
5823:
5822:Tridihexethyl
5820:
5818:
5815:
5813:
5810:
5808:
5807:Propantheline
5805:
5803:
5800:
5798:
5795:
5793:
5790:
5788:
5785:
5783:
5780:
5778:
5775:
5773:
5772:Methantheline
5770:
5768:
5765:
5763:
5760:
5758:
5755:
5753:
5750:
5748:
5747:Fenpiverinium
5745:
5743:
5740:
5738:
5735:
5733:
5730:
5729:
5727:
5723:
5717:
5711:
5708:
5706:
5703:
5701:
5698:
5696:
5693:
5691:
5688:
5686:
5683:
5681:
5678:
5676:
5675:Dicycloverine
5673:
5671:
5668:
5667:
5665:
5659:
5656:
5654:
5650:
5647:
5645:
5635:
5630:
5626:
5618:
5613:
5611:
5606:
5604:
5599:
5598:
5595:
5578:
5577:
5572:
5569:
5566:
5565:
5560:
5557:
5556:
5554:
5552:Miscellaneous
5550:
5540:
5537:
5535:
5528:
5526:
5523:
5521:
5518:
5515:
5512:
5511:
5509:
5505:
5499:
5496:
5494:
5491:
5489:
5486:
5484:
5481:
5480:
5478:
5476:
5472:
5465:
5462:
5459:
5456:
5454:
5451:
5449:
5446:
5445:
5443:
5441:
5437:
5430:
5427:
5425:
5421:
5418:
5416:
5412:
5409:
5405:
5402:
5401:
5399:
5396:
5394:
5390:
5387:
5386:
5384:
5382:
5378:
5368:
5365:
5362:
5358:
5355:
5352:
5348:
5345:
5344:
5342:
5340:
5339:Glutamatergic
5336:
5329:
5326:
5324:
5321:
5319:
5316:
5315:
5313:
5311:
5307:
5304:
5302:
5298:
5287:
5284:
5281:
5274:
5271:
5269:
5266:
5265:
5263:
5261:
5257:
5250:
5244:
5242:
5236:
5234:
5227:
5224:
5222:
5219:
5218:
5216:
5214:
5213:Histaminergic
5210:
5203:
5200:
5198:
5195:
5193:
5190:
5189:
5187:
5185:
5181:
5174:
5171:
5168:
5165:
5162:
5159:
5157:
5153:
5149:
5146:
5143:
5140:
5138:
5134:
5131:
5129:
5125:
5122:
5121:
5119:
5117:
5113:
5110:
5108:
5104:
5100:
5097:
5095:
5090:
5086:
5082:
5077:
5075:
5071:
5067:
5066:
5060:
5058:
5054:
5051:
5047:
5041:
5038:
5036:
5032:
5031:
5027:
5024:
5021:
5018:
5015:
5011:
5007:
5006:
5002:
4999:
4996:
4993:
4991:
4988:
4986:
4983:
4981:
4978:
4976:
4972:
4968:
4967:
4964:
4961:
4959:
4955:
4951:
4950:
4947:
4944:
4942:
4938:
4934:
4933:
4931:
4927:
4923:
4916:
4911:
4909:
4904:
4902:
4897:
4896:
4893:
4880:
4879:
4874:
4871:
4870:
4865:
4862:
4861:
4856:
4853:
4852:
4847:
4844:
4843:
4842:Serotonergics
4838:
4835:
4834:
4829:
4826:
4825:
4822:
4817:
4816:
4813:
4803:
4800:
4798:
4795:
4793:
4790:
4788:
4785:
4783:
4780:
4778:
4775:
4773:
4770:
4768:
4765:
4763:
4762:Sonepiprazole
4760:
4758:
4755:
4753:
4750:
4748:
4745:
4743:
4740:
4738:
4735:
4733:
4730:
4728:
4725:
4723:
4720:
4718:
4715:
4713:
4710:
4708:
4705:
4703:
4700:
4698:
4695:
4693:
4690:
4688:
4685:
4683:
4680:
4678:
4677:Iodobenzamide
4675:
4673:
4670:
4668:
4665:
4663:
4660:
4658:
4655:
4653:
4650:
4648:
4645:
4643:
4640:
4638:
4637:Bromocriptine
4635:
4633:
4630:
4628:
4625:
4623:
4620:
4618:
4614:
4611:
4610:
4607:
4604:
4602:
4599:
4597:
4594:
4592:
4589:
4587:
4583:
4580:
4579:
4576:
4573:
4571:
4568:
4566:
4563:
4561:
4558:
4556:
4553:
4551:
4548:
4546:
4543:
4541:
4538:
4536:
4533:
4531:
4528:
4526:
4523:
4521:
4518:
4516:
4513:
4511:
4510:Benzquinamide
4508:
4506:
4503:
4501:
4498:
4496:
4493:
4491:
4487:
4484:
4483:
4480:
4477:
4475:
4472:
4470:
4467:
4465:
4462:
4460:
4457:
4455:
4452:
4450:
4447:
4445:
4442:
4440:
4437:
4435:
4432:
4430:
4427:
4425:
4422:
4420:
4417:
4415:
4412:
4410:
4407:
4405:
4402:
4399:
4395:
4392:
4390:
4387:
4385:
4382:
4380:
4377:
4375:
4372:
4370:
4367:
4365:
4362:
4360:
4357:
4355:
4352:
4350:
4347:
4345:
4342:
4340:
4337:
4335:
4332:
4330:
4329:DHA-clozapine
4327:
4325:
4322:
4320:
4317:
4315:
4312:
4310:
4307:
4305:
4302:
4300:
4297:
4295:
4292:
4290:
4287:
4285:
4282:
4280:
4277:
4275:
4271:
4268:
4267:
4264:
4261:
4259:
4256:
4254:
4253:Trifluperidol
4251:
4249:
4246:
4243:
4239:
4236:
4234:
4231:
4229:
4226:
4224:
4221:
4219:
4216:
4214:
4213:Thiopropazate
4211:
4209:
4206:
4204:
4201:
4199:
4196:
4194:
4193:Sulforidazine
4191:
4189:
4186:
4184:
4181:
4179:
4176:
4174:
4171:
4169:
4166:
4164:
4161:
4159:
4156:
4154:
4151:
4148:
4144:
4141:
4139:
4136:
4134:
4131:
4129:
4126:
4124:
4121:
4119:
4116:
4114:
4111:
4109:
4106:
4104:
4101:
4099:
4096:
4094:
4093:Levosulpiride
4091:
4089:
4086:
4084:
4081:
4079:
4076:
4074:
4071:
4069:
4066:
4064:
4063:Fluprothixene
4061:
4059:
4056:
4053:
4049:
4046:
4044:
4041:
4039:
4036:
4034:
4031:
4029:
4026:
4024:
4021:
4019:
4016:
4014:
4011:
4009:
4006:
4004:
4001:
3999:
3996:
3994:
3991:
3989:
3986:
3984:
3981:
3979:
3976:
3974:
3971:
3969:
3966:
3964:
3961:
3959:
3956:
3954:
3951:
3949:
3945:
3942:
3941:
3939:
3935:
3929:
3926:
3924:
3921:
3919:
3916:
3914:
3911:
3909:
3906:
3904:
3901:
3899:
3896:
3894:
3891:
3889:
3886:
3884:
3881:
3879:
3876:
3874:
3871:
3869:
3866:
3864:
3861:
3859:
3856:
3854:
3851:
3849:
3846:
3844:
3841:
3839:
3838:Phencyclidine
3836:
3834:
3831:
3829:
3826:
3824:
3821:
3819:
3816:
3814:
3811:
3809:
3806:
3804:
3801:
3799:
3796:
3794:
3791:
3789:
3786:
3784:
3781:
3779:
3776:
3774:
3771:
3769:
3766:
3764:
3761:
3759:
3756:
3754:
3751:
3749:
3746:
3744:
3741:
3739:
3736:
3734:
3731:
3729:
3726:
3724:
3721:
3719:
3715:
3712:
3711:
3708:
3705:
3703:
3700:
3698:
3695:
3693:
3690:
3688:
3687:Brilaroxazine
3685:
3683:
3682:Brexpiprazole
3680:
3678:
3675:
3673:
3670:
3667:
3663:
3660:
3658:
3654:
3651:
3650:
3647:
3644:
3642:
3639:
3637:
3631:
3629:
3623:
3621:
3615:
3613:
3610:
3608:
3605:
3603:
3600:
3598:
3594:
3591:
3590:
3587:
3584:
3582:
3579:
3577:
3576:Dihydrexidine
3574:
3572:
3569:
3567:
3563:
3560:
3559:
3556:
3553:
3551:
3548:
3546:
3543:
3541:
3538:
3536:
3533:
3531:
3528:
3526:
3523:
3521:
3518:
3516:
3513:
3511:
3508:
3506:
3505:Bromocriptine
3502:
3499:
3498:
3495:
3492:
3490:
3487:
3485:
3482:
3480:
3477:
3475:
3471:
3468:
3467:
3464:
3461:
3459:
3456:
3454:
3450:
3447:
3446:
3444:
3440:
3437:
3435:
3427:
3417:
3414:
3412:
3409:
3407:
3404:
3402:
3399:
3397:
3394:
3392:
3389:
3387:
3383:
3380:
3379:
3376:
3373:
3371:
3368:
3366:
3363:
3361:
3358:
3356:
3353:
3351:
3348:
3346:
3343:
3340:
3336:
3333:
3331:
3330:Norquetiapine
3328:
3326:
3323:
3321:
3318:
3316:
3313:
3311:
3310:DHA-clozapine
3308:
3306:
3303:
3301:
3298:
3296:
3293:
3291:
3287:
3284:
3283:
3280:
3277:
3274:
3270:
3267:
3265:
3262:
3260:
3257:
3255:
3252:
3249:
3245:
3242:
3240:
3237:
3235:
3232:
3229:
3225:
3222:
3220:
3217:
3215:
3212:
3210:
3206:
3203:
3202:
3200:
3196:
3190:
3187:
3185:
3182:
3180:
3176:
3173:
3172:
3170:
3166:
3160:
3157:
3155:
3152:
3150:
3147:
3145:
3142:
3140:
3137:
3135:
3132:
3130:
3127:
3125:
3122:
3120:
3117:
3115:
3112:
3110:
3107:
3105:
3102:
3100:
3096:
3093:
3092:
3089:
3086:
3084:
3078:
3076:
3070:
3068:
3065:
3063:
3057:
3055:
3052:
3050:
3047:
3045:
3042:
3040:
3037:
3035:
3031:
3028:
3027:
3024:
3021:
3019:
3016:
3014:
3011:
3009:
3008:Dihydrexidine
3006:
3004:
3001:
2999:
2996:
2994:
2990:
2987:
2986:
2983:
2980:
2978:
2975:
2973:
2970:
2968:
2965:
2963:
2960:
2958:
2955:
2953:
2949:
2946:
2945:
2942:
2939:
2937:
2934:
2932:
2929:
2927:
2924:
2922:
2919:
2917:
2914:
2912:
2909:
2907:
2904:
2902:
2898:
2895:
2894:
2892:
2888:
2885:
2883:
2875:
2871:
2868:
2861:
2856:
2854:
2849:
2847:
2842:
2841:
2838:
2831:
2827:
2824:
2823:
2819:
2810:
2806:
2801:
2796:
2792:
2788:
2784:
2780:
2776:
2769:
2766:
2761:
2757:
2752:
2747:
2743:
2739:
2736:(3): 248β62.
2735:
2731:
2727:
2720:
2717:
2712:
2708:
2703:
2698:
2695:(4): 379β90.
2694:
2690:
2686:
2679:
2676:
2671:
2667:
2663:
2659:
2652:
2649:
2644:
2640:
2636:
2632:
2628:
2624:
2620:
2616:
2609:
2606:
2601:
2597:
2592:
2587:
2583:
2579:
2576:(2): 163β74.
2575:
2571:
2567:
2560:
2558:
2554:
2549:
2545:
2541:
2537:
2533:
2529:
2522:
2519:
2514:
2510:
2506:
2502:
2498:
2494:
2490:
2486:
2479:
2476:
2471:
2467:
2462:
2457:
2452:
2447:
2443:
2439:
2435:
2428:
2425:
2420:
2416:
2412:
2408:
2404:
2397:
2390:
2387:
2382:
2378:
2373:
2368:
2363:
2358:
2354:
2350:
2346:
2339:
2337:
2333:
2328:
2324:
2319:
2314:
2309:
2304:
2300:
2296:
2292:
2285:
2282:
2277:
2273:
2269:
2265:
2261:
2257:
2250:
2247:
2242:
2238:
2233:
2228:
2224:
2220:
2216:
2209:
2207:
2205:
2201:
2196:
2192:
2187:
2182:
2178:
2174:
2170:
2166:
2162:
2155:
2153:
2149:
2144:
2140:
2136:
2132:
2125:
2123:
2121:
2117:
2112:
2108:
2103:
2098:
2094:
2090:
2086:
2082:
2078:
2071:
2069:
2065:
2060:
2056:
2051:
2046:
2042:
2038:
2031:
2029:
2027:
2025:
2023:
2021:
2019:
2017:
2013:
2008:
2004:
2000:
1996:
1993:(3): 545β63.
1992:
1988:
1984:
1977:
1975:
1973:
1969:
1964:
1960:
1955:
1950:
1946:
1942:
1939:(3): 265β82.
1938:
1934:
1930:
1923:
1921:
1919:
1915:
1910:
1906:
1901:
1896:
1891:
1886:
1882:
1878:
1874:
1867:
1865:
1863:
1861:
1859:
1857:
1855:
1853:
1851:
1847:
1842:
1838:
1834:
1830:
1823:
1821:
1819:
1815:
1810:
1806:
1802:
1798:
1794:
1790:
1787:(4): 353β62.
1786:
1782:
1775:
1773:
1771:
1769:
1767:
1765:
1761:
1756:
1752:
1748:
1744:
1740:
1736:
1732:
1728:
1720:
1717:
1712:
1708:
1704:
1700:
1696:
1692:
1689:(6): 605β16.
1688:
1684:
1677:
1674:
1669:
1665:
1661:
1657:
1653:
1649:
1646:(5): 188β93.
1645:
1641:
1634:
1631:
1626:
1622:
1618:
1614:
1610:
1606:
1603:(4): 515β31.
1602:
1598:
1591:
1588:
1583:
1579:
1575:
1571:
1567:
1563:
1556:
1554:
1552:
1550:
1548:
1546:
1544:
1542:
1540:
1538:
1536:
1534:
1532:
1530:
1528:
1526:
1524:
1520:
1515:
1511:
1507:
1503:
1499:
1495:
1488:
1486:
1484:
1482:
1480:
1478:
1476:
1474:
1472:
1470:
1468:
1466:
1464:
1462:
1460:
1458:
1456:
1454:
1452:
1448:
1443:
1439:
1435:
1431:
1427:
1423:
1419:
1415:
1408:
1406:
1404:
1402:
1400:
1398:
1396:
1394:
1392:
1390:
1388:
1386:
1384:
1382:
1380:
1378:
1376:
1374:
1372:
1370:
1368:
1366:
1364:
1362:
1360:
1358:
1356:
1354:
1352:
1350:
1348:
1346:
1344:
1342:
1340:
1338:
1336:
1334:
1332:
1330:
1328:
1326:
1324:
1322:
1320:
1318:
1316:
1312:
1305:
1292:
1289:
1279:
1276:
1265:
1262:
1261:
1257:
1252:
1249:
1246:
1245:gastroparesis
1238:
1235:
1232:
1229:
1228:
1224:
1219:
1210:
1207:
1196:
1193:
1178:
1175:
1168:
1165:
1142:
1139:
1119:
1116:
1113:
1110:
1096:
1093:
1074:
1071:
1068:
1048:
1045:
1044:
1039:
1024:
1021:
1006:
1003:
992:
989:
988:
987:
981:
973:
968:
944:
941:
930:
927:
909:
906:
891:
888:
886:
883:
881:
878:
876:
873:
871:
868:
849:
846:
827:
824:
821:
797:
794:
791:
788:
786:
783:
782:
777:
751:
748:
745:
741:
733:
730:
729:
728:
721:
716:
707:
703:
700:
698:
695:
693:
689:
685:
683:
680:
677:
673:
670:
667:
660:
657:
648:
641:
640:
638:
635:
634:
632:
625:
624:
622:
619:
617:
613:
612:beta blockers
609:
606:
601:
600:
598:
594:
593:
591:
590:
588:
585:
580:
576:
573:
572:
571:
569:
561:
557:
553:
549:
546:
545:
544:
542:
538:
534:
530:
529:schizophrenia
517:
512:
505:
504:
496:
491:
487:
480:
479:
471:
466:
463:
460:
453:
452:
444:
442:
436:
410:
401:
398:
394:
393:dentate gyrus
390:
386:
382:
378:
374:
366:
365:
357:
348:
346:
342:
338:
334:
330:
327:
323:
319:
315:
311:
307:
303:
296:
295:
287:
285:
275:
257:
255:
245:
233:
224:
217:
215:
213:
209:
205:
201:
198:
194:
190:
186:
185:schizophrenia
182:
178:
174:
171:which blocks
170:
166:
162:
158:
154:
145:
141:
136:
132:
128:
126:
122:
117:
114:
111:
109:
105:
102:
99:
97:
93:
89:
85:
81:
77:
76:Schizophrenia
74:
70:
65:
61:
57:
52:
47:
44:
43:
38:
31:
26:
22:
6136:
6103:
6102:
6052:
6037:
5943:Diisopromine
5898:
5875:
5782:Oxyphenonium
5762:Isopropamide
5700:Piperidolate
5685:Dihexyverine
5574:
5562:
5260:Serotonergic
5196:
5184:Dopaminergic
5063:
4876:
4867:
4858:
4849:
4840:
4831:
4820:
4819:
4772:Stepholidine
4767:Spiroxatrine
4757:Seridopidine
4752:SB-277,011-A
4672:Fenfluramine
4632:Bromerguride
4612:
4606:Trimipramine
4601:Propiomazine
4581:
4560:Promethazine
4555:Metopimazine
4485:
4404:Paliperidone
4349:Fluperlapine
4339:Elopiprazole
4304:Clocapramine
4294:Carpipramine
4269:
4223:Thioridazine
4183:Prothipendyl
4143:Perphenazine
4103:Mesoridazine
4078:Homopipramol
4068:Fluspirilene
4058:Fluphenazine
4013:Clothixamide
4008:Clopenthixol
3983:Chloracizine
3978:Butaperazine
3948:Acepromazine
3943:
3903:Salvinorin A
3713:
3707:Norclozapine
3702:Lumateperone
3662:Aripiprazole
3652:
3592:
3561:
3515:Chanoclavine
3500:
3469:
3448:
3381:
3345:Paliperidone
3325:Norclozapine
3315:Fluperlapine
3285:
3259:Thioridazine
3244:Perphenazine
3234:Fluphenazine
3204:
3174:
3149:Stepholidine
3094:
3029:
2988:
2947:
2897:Benzazepines
2896:
2782:
2778:
2768:
2733:
2729:
2719:
2692:
2688:
2678:
2661:
2657:
2651:
2621:(1): 19β27.
2618:
2614:
2608:
2573:
2569:
2531:
2521:
2488:
2484:
2478:
2441:
2437:
2427:
2402:
2389:
2352:
2348:
2298:
2294:
2284:
2259:
2255:
2249:
2222:
2218:
2168:
2164:
2134:
2087:(1): 41β47.
2084:
2080:
2040:
1990:
1986:
1936:
1932:
1880:
1876:
1832:
1828:
1784:
1780:
1730:
1726:
1719:
1686:
1682:
1676:
1643:
1639:
1633:
1600:
1596:
1590:
1565:
1561:
1500:(1): 25β43.
1497:
1493:
1417:
1413:
1211:blocks the D
1141:Paliperidone
1023:Aripiprazole
982:receptor 5HT
977:
943:Thioridazine
885:Perphenazine
870:Fluspirilene
826:Fluphenazine
785:Clopenthixol
725:
706:dopaminergic
621:Parkinsonism
565:
562:Side effects
521:
437:unlike the D
429:
377:hypothalamus
333:hypothalamus
272:
229:
164:
160:
156:
152:
150:
138:Legal status
40:
6148:Cinitapride
6125:Domperidone
6095:Propulsives
6058:Scopolamine
6046:Hyoscyamine
6003:Trepibutone
5998:Tiropramide
5963:Idanpramine
5892:Cilansetron
5881:antagonists
5846:Drotaverine
5792:Pipenzolate
5787:Penthienate
5767:Mepenzolate
5757:Hexocyclium
5710:Trimebutine
5663:amino group
5576:Amino acids
5475:Opioidergic
5381:Cholinergic
5094:transporter
5074:Ion channel
5010:Transporter
4954:Ion channel
4833:Adrenergics
4737:Pridopidine
4722:Nafadotride
4707:Metergoline
4622:Alpiropride
4570:Trazpiroben
4540:Hydroxyzine
4535:Eticlopride
4530:Domperidone
4500:Alimemazine
4474:Ziprasidone
4469:Zicronapine
4464:Veralipride
4449:Tefludazine
4439:Risperidone
4434:Remoxipride
4419:Pipotiazine
4409:Perospirone
4398:+fluoxetine
4389:Ocaperidone
4384:Mosapramine
4369:Mazapertine
4359:Iloperidone
4354:Gevotroline
4344:Flumezapine
4324:Cyamemazine
4309:Clorotepine
4289:Blonanserin
4274:Amisulpride
4228:Thiothixene
4163:Pipamperone
4128:Perathiepin
4123:Penfluridol
4118:Nemonapride
4073:Haloperidol
4052:+melitracen
4018:Clopimozide
3968:Bromperidol
3937:Antagonists
3928:WAY-100,635
3873:Quinelorane
3868:Quinagolide
3848:Pramipexole
3813:Pardoprunox
3798:Mesulergine
3788:Flibanserin
3778:Dizocilpine
3758:Armodafinil
3748:Apomorphine
3692:Cariprazine
3666:+sertraline
3607:Etilevodopa
3530:Ergocornine
3525:Epicriptine
3510:Cabergoline
3463:Rimantadine
3449:Adamantanes
3370:Ziprasidone
3365:Zicronapine
3360:Tefludazine
3355:Risperidone
3339:+fluoxetine
3320:Iloperidone
3295:Clorotepine
3264:Thiothixene
3254:Pifluthixol
3228:+melitracen
3198:Antagonists
3104:Apomorphine
3049:Etilevodopa
3023:Doxanthrine
3013:Dinapsoline
2952:Cabergoline
2301:: 3007β17.
2225:(1): 1β13.
1278:Nafadotride
1264:Eticlopride
1231:Domperidone
1209:Ziprasidone
1177:Risperidone
1167:Remoxipride
1095:Nemonapride
1067:neutropenia
991:Amisulpride
875:Penfluridol
848:Flupentixol
796:Haloperidol
389:hippocampus
345:hippocampus
308:as well as
204:antiemetics
200:antagonists
144:In Wikidata
6165:Ilebopride
6160:Acotiamide
6120:Clebopride
6115:Bromopride
6110:Alizapride
6022:Belladonna
5993:Simeticone
5958:Fenpiprane
5953:Fenoverine
5933:Caroverine
5856:Papaverine
5851:Moxaverine
5838:inhibitors
5817:Timepidium
5742:Diphemanil
5720:Quaternary
5705:Rociverine
5690:Mebeverine
5680:Difemerine
5640:functional
5623:Drugs for
5424:Ganglionic
5415:Muscarinic
5393:Muscarinic
5116:Adrenergic
4985:Antagonist
4742:Raclopride
4732:PNU-99,194
4727:Nuciferine
4667:Fananserin
4662:Fallypride
4591:Nefazodone
4520:Clebopride
4515:Bromopride
4505:Alizapride
4459:Tiospirone
4454:Tenilapine
4444:Sertindole
4429:Quetiapine
4424:Piquindone
4394:Olanzapine
4364:Lurasidone
4334:Dixyrazine
4299:Cinuperone
4258:Zetidoline
4233:Timiperone
4208:Teflutixol
4203:Sultopride
4043:Fluotracen
4038:Flucindole
4033:Fluanisone
4028:Fluacizine
4023:Droperidol
4003:Ciclindole
3973:Butaclamol
3963:Benperidol
3923:Umespirone
3918:Talipexole
3913:Sumanirole
3908:SKF-83,959
3893:Ropinirole
3878:Quinpirole
3833:PF-592,379
3828:PF-219,061
3823:PD-168,077
3818:PD-128,907
3783:Esketamine
3773:CP-226,269
3768:Captodiame
3753:Arketamine
3677:Bifeprunox
3641:Melevodopa
3602:Dopexamine
3581:Dinoxyline
3535:Lergotrile
3489:Rotigotine
3453:Amantadine
3350:Quetiapine
3335:Olanzapine
3300:Clotiapine
3209:Butaclamol
3144:SKF-89,626
3139:SKF-89,145
3134:Rotigotine
3124:PF 6669571
3119:PF-6649751
3114:Nuciferine
3067:Melevodopa
3044:Dopexamine
3018:Dinoxyline
2957:CY-208,243
2941:Zelandopam
2931:SKF-83,959
2926:SKF-82,958
2921:SKF-81,297
2916:SKF-77,434
2911:SKF-38,393
2906:Fenoldopam
2870:modulators
2135:StatPearls
1883:: 656370.
1306:References
1291:Raclopride
1237:Bromopride
1118:Quetiapine
1112:Olanzapine
790:Droperidol
732:Benperidol
727:activity.
678:resistance
341:cerebellum
328:and retina
42:Drug class
6170:Mosapride
6153:Cisapride
5988:Proxazole
5910:Mosapride
5887:Alosetron
5865:Acting on
5812:Tiemonium
5802:Prifinium
5777:Otilonium
5732:Benzilone
5725:compounds
5670:Camylofin
5644:disorders
5637:Drugs for
5571:Precursor
5420:Nicotinic
5398:Nicotinic
5310:GABAergic
5035:Precursor
5020:Inhibitor
4946:Inhibitor
4821:See also:
4802:Yohimbine
4782:Terguride
4747:Sarizotan
4692:L-745,870
4687:L-741,626
4642:Buspirone
4596:Opipramol
4586:Amoxapine
4379:Molindone
4374:Melperone
4319:Clozapine
4279:Asenapine
4198:Sulpiride
4178:Promazine
4168:Preclamol
4083:Lenperone
3958:Azaperone
3898:Roxindole
3888:Ro10-5824
3863:Pukateine
3853:Preclamol
3843:Piribedil
3803:Modafinil
3743:Aplindore
3738:Adrafinil
3636:-Tyrosine
3612:Ibopamine
3555:Terguride
3550:Pergolide
3501:Ergolines
3484:8-OH-PBZI
3479:7-OH-DPAT
3474:5-OH-DPAT
3458:Memantine
3416:SCH-23390
3411:Perlapine
3386:Berupipam
3305:Clozapine
3290:Asenapine
3189:Mevidalen
3154:Tavapadon
3083:-Tyrosine
3054:Ibopamine
2982:Terguride
2977:Pergolide
2948:Ergolines
2643:260238868
1047:Clozapine
1041:Clozapine
1005:Asenapine
980:serotonin
929:Sulpiride
908:Spiperone
904:receptors
740:serotonin
738:and some
608:Akathisia
597:dystonias
548:Melatonin
511:receptors
501:receptors
486:receptors
476:receptors
459:receptors
449:receptors
373:receptors
362:receptors
302:receptors
292:receptors
6185:Category
6142:agonists
6041:Atropine
5928:Alverine
5904:agonists
5737:Bevonium
5722:ammonium
5661:Tertiary
5559:Cofactor
5429:Muscular
5089:Receptor
5040:Cofactor
5026:Releaser
5014:Enhancer
5008:♦
4971:Receptor
4969:♦
4952:♦
4935:♦
4792:Tiapride
4702:LEK-8829
4627:Azapride
4545:Itopride
4479:Zotepine
4158:Pimozide
4133:Perazine
4108:Moperone
4098:Loxapine
3808:OSU-6162
3793:Ketamine
3723:A-412997
3571:Ciladopa
3566:2-OH-NPA
3540:Lisuride
3442:Agonists
3406:Odapipam
3391:Ecopipam
3375:Zotepine
3239:Loxapine
2972:Lisuride
2967:LEK-8829
2936:Trepipam
2901:6-Br-APB
2890:Agonists
2809:26899245
2760:18801115
2711:14871277
2670:14728084
2635:10721880
2600:25943458
2548:24249315
2505:27121764
2470:25859275
2419:24346956
2381:26220447
2327:26674884
2276:22494521
2241:23295003
2195:15846648
2143:30137788
2111:23983836
2059:14972081
2007:24011886
1963:11607043
1909:24995318
1841:10811237
1801:25516373
1755:29375454
1747:19145986
1711:25508148
1703:12043836
1668:22686973
1660:17368565
1625:30902536
1617:16848689
1514:16613552
1434:21303898
1197:blocks D
1195:Tiapride
1137:effects.
1073:Loxapine
890:Pimozide
880:Perazine
717:Examples
697:Sedation
653:receptor
568:dopamine
541:vomiting
337:thalamus
318:amygdala
314:striatum
212:vomiting
197:dopamine
96:ATC code
88:vomiting
5797:Poldine
5516:(AdoRI)
5466:(eCBRI)
5049:Classes
4975:Agonist
4963:Blocker
4941:Inducer
4657:F-15063
4495:AS-8112
4284:BL-1020
4113:Naranol
3883:RDS-127
3733:ABT-724
3728:ABT-670
3697:F-15063
3646:XP21279
3099:A-68930
3088:XP21279
3034:BCO-001
2998:A-86929
2993:A-77636
2800:4844650
2751:2753830
2591:4488186
2513:4402288
2461:4391595
2372:4518630
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2318:4675633
2186:7017029
2102:3726098
1954:6741677
1900:4065707
1809:8345032
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1442:2545878
1293:binds D
1280:binds D
1266:binds D
1179:binds D
1169:binds D
1143:binds D
1120:binds D
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1075:binds D
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910:binds D
892:binds D
862:, and D
850:binds D
844:as well
828:binds D
798:binds D
752:binds D
734:binds D
688:obesity
676:insulin
179:. Most
131:D012559
5642:bowel
5460:(eCBE)
5057:Enzyme
4958:Opener
4937:Enzyme
4797:UH-232
4777:SV-293
4613:Others
3763:BP-897
3714:Others
3494:UH-232
3382:Others
3095:Others
2832:(MeSH)
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537:nausea
208:nausea
191:, and
159:and a
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5921:Other
5573:(see
5561:(see
5507:Other
5330:(GRI)
5288:(SRI)
5204:(DRI)
5175:(NRI)
5091:&
5003:(NAM)
4997:(PAM)
4929:Types
4617:3-PPP
3718:3-PPP
3434:-like
2882:-like
2639:S2CID
2509:S2CID
2399:(PDF)
1805:S2CID
1751:S2CID
1707:S2CID
1664:S2CID
1621:S2CID
1438:S2CID
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5351:AMPA
5277:5-HT
5079:See
5062:see
5028:(RA)
5022:(RI)
5016:(RE)
4652:EEDQ
3396:EEDQ
3184:DPTQ
3179:DETQ
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2756:PMID
2707:PMID
2666:PMID
2631:PMID
2596:PMID
2544:PMID
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2323:PMID
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2139:PMID
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2003:PMID
1959:PMID
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169:drug
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