17:
339:
46:, titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small. Some examples of the types of drugs commonly requiring titration include
208:
Olson KR, Anderson IB, Benowitz NL, Blanc PD, Clark RF, Kearney TE, Kim-Katz SY, Wu AH, eds. (11 December 2017). "Section III: Therapeutic Drugs and
Antidotes".
20:
Therapeutic (green) and side effect dose response curves (red) illustrating a typical starting and progressively increasing titrated doses (arrows).
183:
Roden DM (2014). "Chapter 5 : Principles of
Clinical Pharmacology". In Kasper D, Fauci A, Hauser S, Longo D, Jameson JL, Loscalzo J (eds.).
380:
242:
217:
192:
167:
142:
304:
88:
is given in increasing dosages until side effects become intolerable. A clinical trial in which a suitable dose is found is called a
404:
103:
77:
373:
233:
Kruidering-Hall M, Campbell L (30 November 2017). "Chapter 27: Skeletal Muscle
Relaxants". In Katzung BG (ed.).
399:
366:
158:
Schachter M, Pirmohamed M (2012). "General
Pharmacology". In Bennett PN, Brown MJ, Sharma P (eds.).
278:
90:
259:
238:
213:
188:
163:
138:
85:
69:
Titrating off of a medication instead of stopping abruptly is recommended in some situations.
43:
350:
130:
290:
59:
36:
111:– chewed as a stimulant (or, after extended use, a depressant) by Aboriginal Australians
81:
70:
51:
393:
55:
346:
32:
16:
338:
63:
131:"Chapter 2: Therapeutics and Good Prescribing: Choosing a Dosing Regime"
47:
108:
73:
should be tapered after extended use to avoid adrenal insufficiency.
28:
133:. In Walker BR, Colledge NR, Ralston SH, Penman ID (eds.).
305:"Dose-Response Information to Support Drug Registration"
354:
135:Davidson's Principles and Practice of Medicine
374:
8:
237:(14th ed.). New York, NY: McGraw-Hill.
187:(19th ed.). New York, NY: McGraw-Hill.
212:(7th ed.). New York, NY: McGraw-Hill.
381:
367:
162:(11 ed.). Elsevier. pp. 74–109.
137:. Elsevier Health Sciences. p. 34.
15:
121:
286:
276:
7:
335:
333:
262:. In Matteson EL, Curtis MR (eds.).
185:Principles of Clinical Pharmacology
353:. You can help Knowledge (XXG) by
14:
235:Basic & Clinical Pharmacology
337:
264:Treatment Issues in Rheumatology
35:for the maximum benefit without
27:is the process of adjusting the
76:Drug titration is also used in
1:
210:Poisoning & Drug Overdose
260:"Glucocorticoid withdrawal"
104:Therapeutic drug monitoring
421:
332:
42:When a drug has a narrow
349:-related article is a
312:Guideline for Industry
21:
160:Clinical Pharmacology
19:
314:. FDA. November 1994
258:Furst DE, Saag KG.
405:Pharmacology stubs
129:Maxwell S (2013).
91:dose-ranging study
22:
362:
361:
244:978-1-259-64115-2
219:978-0-07-183979-2
194:978-0-07-180215-4
169:978-0-7020-4084-9
144:978-0-7020-5103-6
86:experimental drug
44:therapeutic index
412:
383:
376:
369:
341:
334:
324:
323:
321:
319:
309:
301:
295:
294:
288:
284:
282:
274:
272:
270:
255:
249:
248:
230:
224:
223:
205:
199:
198:
180:
174:
173:
155:
149:
148:
126:
60:anti-depressants
420:
419:
415:
414:
413:
411:
410:
409:
390:
389:
388:
387:
330:
328:
327:
317:
315:
307:
303:
302:
298:
285:
275:
268:
266:
257:
256:
252:
245:
232:
231:
227:
220:
207:
206:
202:
195:
182:
181:
177:
170:
157:
156:
152:
145:
128:
127:
123:
118:
100:
82:clinical trials
71:Glucocorticoids
52:anticonvulsants
37:adverse effects
12:
11:
5:
418:
416:
408:
407:
402:
392:
391:
386:
385:
378:
371:
363:
360:
359:
342:
326:
325:
296:
287:|website=
250:
243:
225:
218:
200:
193:
175:
168:
150:
143:
120:
119:
117:
114:
113:
112:
106:
99:
96:
56:blood thinners
25:Drug titration
13:
10:
9:
6:
4:
3:
2:
417:
406:
403:
401:
398:
397:
395:
384:
379:
377:
372:
370:
365:
364:
358:
356:
352:
348:
343:
340:
336:
331:
313:
306:
300:
297:
292:
280:
265:
261:
254:
251:
246:
240:
236:
229:
226:
221:
215:
211:
204:
201:
196:
190:
186:
179:
176:
171:
165:
161:
154:
151:
146:
140:
136:
132:
125:
122:
115:
110:
107:
105:
102:
101:
97:
95:
93:
92:
87:
83:
79:
74:
72:
67:
65:
61:
57:
53:
49:
45:
40:
38:
34:
30:
26:
18:
400:Pharmacology
355:expanding it
347:pharmacology
344:
329:
316:. Retrieved
311:
299:
267:. Retrieved
263:
253:
234:
228:
209:
203:
184:
178:
159:
153:
134:
124:
89:
75:
68:
41:
24:
23:
394:Categories
116:References
33:medication
289:ignored (
279:cite book
64:sedatives
98:See also
318:13 June
269:13 June
78:phase I
48:insulin
241:
216:
191:
166:
141:
109:Pituri
84:. The
62:, and
345:This
308:(PDF)
31:of a
351:stub
320:2018
291:help
271:2018
239:ISBN
214:ISBN
189:ISBN
164:ISBN
139:ISBN
29:dose
80:of
396::
310:.
283::
281:}}
277:{{
94:.
66:.
58:,
54:,
50:,
39:.
382:e
375:t
368:v
357:.
322:.
293:)
273:.
247:.
222:.
197:.
172:.
147:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
