Knowledge (XXG)

External globus pallidus

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The GPe is particular in comparison to the other elements of the set by the fact that it does not work as an output base of the basal ganglia (not sending axons to the thalamus) but as the main regulator of the basal ganglia system. It is sometimes used as a target for
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Direct and indirect striatopallidal pathways: Glutamatergic pathways are red, dopaminergic are magenta and GABAergic pathways are blue. STN: Subthalamic Nucleus SNr: Substantia Nigra pars reticulata SNc: Substantia Nigra pars compacta GPi: Medial globus
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Parent, AndrΓ©; Hazrati, Lili-Naz (1995-01-01). "Functional anatomy of the basal ganglia. II. The place of subthalamic nucleus and external pallidium in basal ganglia circuitry".
325:, functions to modulate the effects of the direct pathway. The GPe acts as an inhibitory "control device", adjusting subthalamic nucleus neuronal activity via GABAergic output. 133: 2200: 1078: 1220: 1168: 1123: 1114: 404:
Parent, AndrΓ©; Hazrati, Lili-Naz (1995-01-01). "Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop".
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indirect striatopallidal pathway allows for regulated excitatory input from the subthalamic nucleus to the GPi and
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means "pale globe" in Latin, indicating its appearance. The external globus pallidus is the segment of the
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Hegeman, Daniel J.; Hong, Ellie S.; HernΓ‘ndez, Vivian M.; Chan, C. Savio (2016-05-01).
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Lateral globus pallidus dysfunction has been observed in the following conditions:
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that is relatively further (lateral) from the midline of the brain.
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functions to tonically inhibit movement, mainly in the absence of
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External globus pallidus (GPe) seen in 2nd image from the left
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When movement adjustment is required, striatal inhibitory
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axons are sent to the GPe, decreasing inhibition of the
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neurons, allow for its inhibitory function and projects
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globus pallidus externus, globus pallidus lateralis
58: 53: 43: 38: 21: 282:of the brain stem. When movement is required, the 2194: 1072: 559: 8: 2201: 2187: 1992: 1789: 1609: 1452: 1395: 1258: 1119: 1110: 1079: 1065: 1057: 957: 881: 804: 602: 593: 566: 552: 544: 27: 523: 1966:Flocculonodular lobe/vestibulocerebellum 1925:Intermediate hemisphere/spinocerebellum 393: 2095:Ventral/anterior spinocerebellar tract 2024:Dorsal/posterior spinocerebellar tract 144: 18: 212:, internal globus pallidus (GPi) and 7: 2155: 2153: 399: 397: 344:neurons then stimulate the GPi and 2173:. You can help Knowledge (XXG) by 1892:Lateral hemisphere/pontocerebellum 1415:Posterior limb of internal capsule 1231:Posterior limb of internal capsule 14: 1186:Posterior external arcuate fibers 321:, which contains the GPe and the 2157: 496:European Journal of Neuroscience 357:substantia nigra pars reticulata 346:substantia nigra pars reticulata 306:is monosynaptic (containing one 296:substantia nigra pars reticulata 214:substantia nigra pars reticulata 141:Anatomical terms of neuroanatomy 290:, which directly inhibits the 177:, an anatomical subset of the 1: 2121:Rostral spinocerebellar tract 822:Anterior perforated substance 461:10.1016/0165-0173(94)00008-D 418:10.1016/0165-0173(94)00007-C 2067:Anterior lobe of cerebellum 16:Part of the globus pallidus 2241: 2152: 2019:Posterior thoracic nucleus 1733:Thalamocortical radiations 1657:Thalamocortical radiations 817:Anterior olfactory nucleus 2053:Accessory cuneate nucleus 1971:Vestibulocerebellar tract 1805:Vestibulocerebellar tract 1579: 1314:Posterior parietal cortex 1281:Anterior white commissure 582:and associated structures 139: 26: 1850:Inferior olivary nucleus 1737:Supplementary motor area 1661:Supplementary motor area 1471:Genu of internal capsule 1323:Spinomesencephalic tract 906:Nucleus of diagonal band 268:ventral anterior nucleus 171:internal globus pallidus 159:external globus pallidus 22:External globus pallidus 1938:Cerebellothalamic tract 1419:Decussation of pyramids 1190:Internal arcuate fibers 855:Lateral olfactory stria 264:ventral lateral nucleus 167:lateral globus pallidus 1872:Deep cerebellar nuclei 1839:Deep cerebellar nuclei 1830:Pontocerebellar fibers 1705:Subthalamic fasciculus 1697:Subthalamic fasciculus 1438:Neuromuscular junction 924:Diagonal band of Broca 850:Medial olfactory stria 786:Subthalamic fasciculus 764:Pallidothalamic tracts 449:Brain Research Reviews 406:Brain Research Reviews 304:medial globus pallidus 292:medial globus pallidus 286:sends commands to the 242: 222:deep brain stimulation 2058:Cuneocerebellar tract 1901:Dentatothalamic tract 1855:Olivocerebellar tract 1752:nigrostriatal pathway 1713:Lenticular fasciculus 1637:Lenticular fasciculus 1540:Vestibulospinal tract 948:Hippocampal formation 894:Substantia innominata 779:Lenticular fasciculus 280:mesopontine tegmentum 239: 1570:Reticulospinal tract 1481:Facial motor nucleus 1467:Primary motor cortex 1411:Primary motor cortex 1357:Spinoreticular tract 1198:Trigeminal lemniscus 1137:Meissner's corpuscle 377:Huntington's disease 310:), it is called the 169:) combines with the 1933:Reticular formation 1721:Thalamic fasciculus 1701:Subthalamic nucleus 1645:Thalamic fasciculus 1565:Reticular formation 1561:Vestibulocerebellum 1531:Vestibulocerebellum 1476:Corticobulbar tract 1424:Corticospinal tract 1362:Reticular formation 1352:Group C nerve fiber 1328:Superior colliculus 1293:Spinothalamic tract 1180:sensory decussation 1042:Schaffer collateral 953:Hippocampus anatomy 769:Thalamic fasciculus 372:Parkinson's disease 338:subthalamic nucleus 334:subthalamic nucleus 323:subthalamic nucleus 276:superior colliculus 226:Parkinson's disease 224:as a treatment for 202:subthalamic nucleus 2225:Neuroanatomy stubs 2116:Golgi tendon organ 2090:Golgi tendon organ 1921:Interposed nucleus 1151:Cuneate fasciculus 1147:Gracile fasciculus 1133:Pacinian corpuscle 970:Hippocampus proper 644:Olfactory tubercle 262:inhibition of the 243: 173:(GPi) to form the 2182: 2181: 2147: 2146: 2143: 2142: 2139: 2138: 2104:Cerebellar vermis 2033:Cerebellar vermis 1976:Vestibular nuclei 1962:Fastigial nucleus 1800:Vestibular nuclei 1779: 1778: 1775: 1774: 1717:Ansa lenticularis 1641:Ansa lenticularis 1599: 1598: 1592:β†’ muscles of neck 1589:Tectospinal tract 1535:Vestibular nuclei 1510:Rubrospinal tract 1387: 1386: 1383: 1382: 1310:Postcentral gyrus 1273:Free nerve ending 1243: 1242: 1235:Postcentral gyrus 1054: 1053: 1050: 1049: 937: 936: 870: 869: 862:Olfactory trigone 794: 793: 774:Ansa lenticularis 708:Centrum semiovale 694: 693: 639:Nucleus accumbens 508:10.1111/ejn.13196 502:(10): 1239–1265. 363:Related pathology 274:, as well as the 155: 154: 150: 2232: 2203: 2196: 2189: 2161: 2154: 1993: 1790: 1756: 1679: 1619: 1610: 1554: 1524: 1498: 1460: 1453: 1396: 1374:Cingulate cortex 1298:Spinal lemniscus 1259: 1194:Medial lemniscus 1142:Posterior column 1120: 1111: 1081: 1074: 1067: 1058: 958: 929:Stria terminalis 882: 805: 751:External capsule 715:Internal capsule 634:Ventral striatum 603: 594: 568: 561: 554: 545: 538: 537: 527: 487: 481: 480: 444: 438: 437: 401: 319:indirect pathway 246:Indirect pathway 147:edit on Wikidata 31: 19: 2240: 2239: 2235: 2234: 2233: 2231: 2230: 2229: 2210: 2209: 2208: 2207: 2150: 2148: 2135: 2072: 2045:muscle spindles 2011:muscle spindles 1998: 1988:Spinocerebellar 1986: 1980: 1888:Dentate nucleus 1876: 1771: 1749: 1744: 1673: 1668: 1613: 1595: 1584:Midbrain tectum 1575: 1550: 1545: 1520: 1515: 1494: 1489: 1456: 1442: 1379: 1336: 1332:Midbrain tectum 1252: 1239: 1215: 1182:/arcuate fibers 1163: 1159:Cuneate nucleus 1155:Gracile nucleus 1102: 1085: 1055: 1046: 1013: 951: 946: 933: 910: 899:Nucleus basalis 877:basal forebrain 866: 845:Olfactory tract 831: 790: 756:Extreme capsule 735:Optic radiation 690: 669: 653:Globus pallidus 625:Caudate nucleus 615:Dorsal striatum 583: 572: 542: 541: 489: 488: 484: 446: 445: 441: 403: 402: 395: 390: 365: 284:cerebral cortex 248: 234: 187:globus pallidus 183:Globus pallidus 175:globus pallidus 151: 48:Globus pallidus 34: 17: 12: 11: 5: 2238: 2236: 2228: 2227: 2222: 2212: 2211: 2206: 2205: 2198: 2191: 2183: 2180: 2179: 2162: 2145: 2144: 2141: 2140: 2137: 2136: 2134: 2133: 2108: 2107: 2082: 2080: 2074: 2073: 2071: 2070: 2037: 2036: 2003: 2001: 1999:proprioception 1990: 1985:Bidirectional: 1982: 1981: 1979: 1978: 1958: 1957: 1917: 1916: 1884: 1882: 1878: 1877: 1875: 1874: 1846: 1845: 1825:Pontine nuclei 1821: 1820: 1796: 1794: 1787: 1781: 1780: 1777: 1776: 1773: 1772: 1770: 1769: 1759: 1757: 1746: 1745: 1682: 1680: 1670: 1669: 1622: 1620: 1607: 1601: 1600: 1597: 1596: 1594: 1593: 1580: 1577: 1576: 1574: 1573: 1557: 1555: 1547: 1546: 1544: 1543: 1527: 1525: 1517: 1516: 1514: 1513: 1501: 1499: 1491: 1490: 1488: 1487: 1485:Facial muscles 1463: 1461: 1450: 1448:Extrapyramidal 1444: 1443: 1441: 1440: 1404: 1402: 1393: 1389: 1388: 1385: 1384: 1381: 1380: 1378: 1377: 1347: 1345: 1338: 1337: 1318: 1317: 1268: 1266: 1256: 1245: 1244: 1241: 1240: 1238: 1237: 1226: 1224: 1217: 1216: 1214: 1213: 1174: 1172: 1165: 1164: 1162: 1161: 1129: 1127: 1117: 1108: 1104: 1103: 1086: 1084: 1083: 1076: 1069: 1061: 1052: 1051: 1048: 1047: 1045: 1044: 1039: 1037:Perforant path 1034: 1029: 1023: 1021: 1015: 1014: 1012: 1011: 1006: 1005: 1004: 1002:Fascia dentata 994: 993: 992: 987: 982: 977: 966: 964: 955: 939: 938: 935: 934: 932: 931: 926: 920: 918: 912: 911: 909: 908: 903: 902: 901: 890: 888: 879: 872: 871: 868: 867: 865: 864: 859: 858: 857: 852: 841: 839: 833: 832: 830: 829: 827:Olfactory bulb 824: 819: 813: 811: 802: 800:Rhinencephalon 796: 795: 792: 791: 789: 788: 783: 782: 781: 776: 759: 758: 753: 747: 746: 744:Corona radiata 740: 739: 738: 737: 732: 730:Posterior limb 727: 722: 711: 710: 704: 702: 696: 695: 692: 691: 689: 688: 683: 677: 675: 671: 670: 668: 667: 666: 665: 660: 649: 648: 647: 646: 641: 630: 629: 628: 627: 622: 611: 609: 600: 591: 585: 584: 573: 571: 570: 563: 556: 548: 540: 539: 482: 455:(1): 128–154. 439: 392: 391: 389: 386: 385: 384: 379: 374: 364: 361: 312:direct pathway 247: 244: 233: 230: 153: 152: 143: 137: 136: 131: 125: 124: 119: 113: 112: 107: 101: 100: 95: 88: 87: 82: 76: 75: 72: 68: 67: 62: 56: 55: 51: 50: 45: 41: 40: 36: 35: 32: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 2237: 2226: 2223: 2221: 2220:Basal ganglia 2218: 2217: 2215: 2204: 2199: 2197: 2192: 2190: 2185: 2184: 2178: 2176: 2172: 2169:article is a 2168: 2163: 2160: 2156: 2151: 2131: 2127: 2123: 2122: 2117: 2113: 2110: 2109: 2105: 2101: 2097: 2096: 2091: 2087: 2084: 2083: 2081: 2079: 2075: 2068: 2064: 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360: 358: 354: 353:multisynaptic 349: 347: 343: 342:glutamatergic 339: 335: 331: 326: 324: 320: 315: 313: 309: 305: 301: 297: 293: 289: 285: 281: 277: 273: 269: 265: 261: 258:command, via 257: 253: 252:basal ganglia 245: 238: 231: 229: 227: 223: 217: 215: 211: 207: 203: 199: 195: 190: 188: 184: 180: 179:basal ganglia 176: 172: 168: 164: 160: 148: 142: 138: 135: 132: 130: 126: 123: 120: 118: 114: 111: 108: 106: 102: 99: 96: 93: 89: 86: 83: 81: 77: 73: 69: 66: 63: 61: 57: 52: 49: 46: 42: 37: 30: 25: 20: 2175:expanding it 2167:neuroanatomy 2164: 2149: 2119: 2093: 2056: 2022: 1969: 1955:Motor cortex 1936: 1914:Motor cortex 1899: 1853: 1843:Granule cell 1828: 1818:Granule cell 1803: 1750: 1741:Motor cortex 1685:Motor cortex 1675: 1665:Motor cortex 1625:Motor cortex 1615: 1587: 1568: 1551: 1538: 1521: 1508: 1495: 1474: 1457: 1422: 1407: 1355: 1321: 1319: 1284: 1178: 1140: 1019:White matter 916:White matter 837:White matter 762: 700:White matter 499: 495: 485: 452: 448: 442: 409: 405: 366: 350: 327: 316: 256:motor cortex 249: 218: 206:diencephalon 191: 166: 162: 158: 156: 110:A14.1.09.509 98:birnlex_1610 64: 1997:Unconscious 1943:Red nucleus 1505:Red nucleus 1092:spinal cord 962:Grey matter 943:Archicortex 886:Grey matter 809:Grey matter 598:Grey matter 580:human brain 54:Identifiers 2214:Categories 2130:Cerebellum 2112:upper limb 2086:lower limb 2078:Reflex arc 2041:upper limb 2007:lower limb 1864:Hemisphere 1814:Cerebellum 1785:Cerebellar 1663:) β†’ 5Β° ( 1552:extension: 1522:extension: 388:References 80:NeuroNames 71:Acronym(s) 1739:) β†’ 7Β° ( 1676:indirect: 1400:Pyramidal 1100:fasciculi 1009:Subiculum 686:Claustrum 516:1460-9568 330:GABAergic 260:GABAergic 194:GABAergic 2118:) β†’ 2Β° ( 2092:) β†’ 2Β° ( 2051:) β†’ 2Β° ( 2017:) β†’ 2Β° ( 1947:Thalamus 1906:Thalamus 1881:Efferent 1793:Afferent 1767:Striatum 1731:) β†’ 6Β° ( 1729:Thalamus 1711:) β†’ 5Β° ( 1703:) β†’ 4Β° ( 1695:) β†’ 3Β° ( 1691:) β†’ 2Β° ( 1689:Striatum 1655:) β†’ 4Β° ( 1653:Thalamus 1635:) β†’ 3Β° ( 1631:) β†’ 2Β° ( 1629:Striatum 1496:flexion: 1458:flexion: 1432:Anterior 1408:flexion: 1372:) β†’ 3Β° ( 1370:Thalamus 1364:) β†’ 2Β° ( 1312:) β†’ 4Β° ( 1308:) β†’ 3Β° ( 1306:Thalamus 1290:Anterior 1279:) β†’ 2Β° ( 1265:/lateral 1202:Thalamus 681:Amygdala 607:Striatum 574:Rostral 534:26841063 477:20808851 434:28252990 382:Dystonia 300:striatum 288:striatum 272:thalamus 241:pallidus 232:Function 210:striatum 204:(in the 192:The GPe 92:NeuroLex 1935:, or β†’ 1616:direct: 1428:Lateral 1344:/medial 1286:Lateral 1107:Sensory 1032:Fimbria 620:Putamen 578:of the 525:4874844 469:7711765 426:7711769 308:synapse 302:to the 270:of the 208:), the 200:to the 44:Part of 39:Details 2114:β†’ 1Β° ( 2088:β†’ 1Β° ( 2043:β†’ 1Β° ( 2009:β†’ 1Β° ( 1027:Alveus 875:Other 532:  522:  514:  475:  467:  432:  424:  336:. The 2165:This 1392:Motor 1088:Brain 674:Other 473:S2CID 430:S2CID 351:This 198:axons 145:[ 134:61839 60:Latin 2171:stub 1953:) β†’ 1912:) β†’ 1683:1Β° ( 1623:1Β° ( 1350:1Β° ( 1342:Slow 1320:2Β° ( 1288:and 1271:1Β° ( 1263:Fast 1254:pain 1192:) β†’ 1153:) β†’ 1115:DCML 1098:and 1090:and 725:Genu 530:PMID 512:ISSN 465:PMID 422:PMID 317:The 294:and 278:and 266:and 250:The 157:The 122:5570 105:TA98 2126:ICP 2100:SCP 2063:ICP 2049:DRG 2029:ICP 2015:DRG 1964:in 1929:SCP 1923:in 1896:SCP 1890:in 1860:ICP 1852:β†’ 1835:MCP 1810:ICP 1727:of 1709:GPi 1693:GPe 1651:of 1633:GPi 1533:β†’ 1368:of 1330:of 1304:of 1302:VPL 1210:VPM 1206:VPL 990:CA4 985:CA3 980:CA2 975:CA1 663:GPi 658:GPe 520:PMC 504:doi 457:doi 414:doi 165:or 163:GPe 129:FMA 117:TA2 85:232 74:GPe 2216:: 2128:β†’ 2124:β†’ 2102:β†’ 2098:β†’ 2065:β†’ 2061:β†’ 2055:β†’ 2047:β†’ 2031:β†’ 2027:β†’ 2021:β†’ 2013:β†’ 1974:β†’ 1968:β†’ 1951:VL 1945:β†’ 1941:β†’ 1931:β†’ 1927:β†’ 1910:VL 1904:β†’ 1898:β†’ 1894:β†’ 1870:β†’ 1866:β†’ 1862:β†’ 1858:β†’ 1841:β†’ 1837:β†’ 1833:β†’ 1827:β†’ 1816:β†’ 1812:β†’ 1808:β†’ 1802:β†’ 1765:β†’ 1735:β†’ 1725:VL 1723:β†’ 1719:β†’ 1707:β†’ 1699:β†’ 1687:β†’ 1659:β†’ 1649:VL 1647:β†’ 1643:β†’ 1627:β†’ 1586:β†’ 1567:β†’ 1563:β†’ 1537:β†’ 1507:β†’ 1483:β†’ 1479:β†’ 1473:β†’ 1469:β†’ 1436:β†’ 1430:, 1421:β†’ 1417:β†’ 1413:β†’ 1366:MD 1360:β†’ 1354:β†’ 1334:) 1326:β†’ 1300:β†’ 1296:β†’ 1283:β†’ 1275:β†’ 1233:β†’ 1229:β†’ 1221:3Β° 1208:, 1200:β†’ 1188:, 1177:β†’ 1169:2Β° 1139:β†’ 1124:1Β° 1094:: 528:. 518:. 510:. 500:43 498:. 494:. 471:. 463:. 453:20 451:. 428:. 420:. 410:20 408:. 396:^ 348:. 340:' 314:. 228:. 216:. 181:. 94:ID 2202:e 2195:t 2188:v 2177:. 2132:) 2106:) 2069:) 2035:) 1949:( 1908:( 1754:: 1743:) 1715:/ 1667:) 1639:/ 1434:) 1426:( 1376:) 1316:) 1251:/ 1223:: 1212:) 1204:( 1196:/ 1184:( 1171:: 1157:/ 1149:/ 1145:( 1135:/ 1126:: 1080:e 1073:t 1066:v 950:/ 945:: 766:: 567:e 560:t 553:v 536:. 506:: 479:. 459:: 436:. 416:: 161:( 149:]

Index


Globus pallidus
Latin
NeuroNames
232
NeuroLex
birnlex_1610
TA98
A14.1.09.509
TA2
5570
FMA
61839
Anatomical terms of neuroanatomy
edit on Wikidata
internal globus pallidus
globus pallidus
basal ganglia
Globus pallidus
globus pallidus
GABAergic
axons
subthalamic nucleus
diencephalon
striatum
substantia nigra pars reticulata
deep brain stimulation
Parkinson's disease

basal ganglia

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