39:
83:
of the skin, accounting for less than 0.01% of diagnosed cutaneous malignancies. Eccrine carcinoma tumors are locally aggressive, with a high rate of recurrence. Lack of reliable immunohistochemical markers and similarity to other common tumors has made identification of eccrine carcinoma difficult.
137:
A skin biopsy is the most common test used to diagnose eccrine carcinoma. The biopsy will detect growth of new or abnormal tissue. Another test that can be performed is using immunohistochemistry, but it is inconsistent. Markers used to detect eccrine carcinoma consist of carcinoembryonic antigen,
120:
Eccrine carcinomas include porocarcinoma, hidradenocarcinoma, malignant spiradenoma carcinoma, malignant cylindroma, syringoid eccrine carcinoma, microcystic adnexal carcinoma, mucinous carcinoma, adenoid cystic carcinoma, and ductal papillary adenocarcinoma. Other tumors not classified include
154:
In the absence of metastasis, local excision is curative in 70–80% of cases. Metastatic eccrine carcinoma has a relative mortality rate of 65% (with local lymph node involvement alone) to 80% (with distant metastases), and the 10-year overall survival rate is 9%.
103:
Eccrine carcinoma results in brown, bluish, erythematous skin lesions across the body. Common regions where lesions are found are in the lower extremities (35%), head and neck (24%), and upper extremities (14%).
723:
337:
Idrissi
Serhrouchni, Karima; Harmouch, Taoufiq; Chbani, Laila; El Fatemi, Hind; Sekal, Mohammed; Hammas, Nawal; Soughi, Meriem; Benchat, Loubna; Amarti, Afaf (2013-02-04).
541:
Sidiropoulos, M.; Sade, S.; Al-Habeeb, A.; Ghazarian, D. (2011-06-04). "Syringoid eccrine carcinoma: a clinicopathological and immunohistochemical study of four cases".
396:
Swanson, P. E.; Cherwitz, D. L.; Neumann, M. P.; Wick, M. R. (1987–2004). "Eccrine sweat gland carcinoma: an histologic and immunohistochemical study of 32 cases*".
1144:
597:
Salih, Abdulwahid M.; Kakamad, F.H.; Essa, Rawand A.; Rauf, Goran M.; S.A., Masrur; H.M., Shvan; Q.S., Rawezh; A.H., Hunar; A.H., Dahat; Othman, Snur (2017).
716:
1101:
1096:
1073:
978:
709:
206:
1058:
1030:
447:
Ohnishi, Takamitsu; Kaneko, Sakae; Egi, Motoko; Takizawa, Hajime; Watanabe, Shinichi (2002–2010). "Syringoid
Eccrine Carcinoma".
1025:
825:
498:
Moy, Ronald L.; Rivkin, Jonathan E.; Lee, Hyo; Brooks, Walter S.; Zitelli, John A. (1991–2005). "Syringoid eccrine carcinoma".
146:
Wide surgical excision is the mainstay of treatment. Chemotherapy and radiation therapy have been used in metastatic disease.
988:
121:
eccrine ductal carcinoma, basaloid eccrine carcinoma, clear cell eccrine carcinoma and non-specified sweat gland carcinomas.
1091:
993:
172:
983:
770:
1123:
928:
840:
908:
138:
progesterone receptors, estrogen receptors, epithelial membrane antigen, pancytokeratins, and cytokeratin 7.
968:
1068:
1020:
933:
830:
795:
278:
Larson, Kristian; Babiker, Hani M.; Kovoor, Andrew; Liau, Joy; Eldersveld, Jordan; Elquza, Emad (2018).
859:
805:
913:
855:
785:
762:
92:
80:
881:
876:
574:
480:
429:
1040:
973:
918:
818:
638:
620:
566:
558:
523:
515:
472:
464:
421:
413:
378:
360:
319:
301:
252:
202:
51:
1063:
1010:
628:
610:
550:
507:
456:
405:
368:
350:
309:
291:
903:
895:
689:
112:
Metastases and/or antagonistic side effects can occur after surgical excision of tumors.
1115:
1005:
845:
736:
633:
598:
409:
373:
338:
314:
279:
68:
1138:
1035:
1015:
1000:
964:
780:
511:
460:
578:
484:
1045:
835:
701:
433:
38:
554:
872:
790:
753:
615:
177:
163:
Eccrine carcinoma accounts for 0.005-0.01% of diagnosed cutaneous malignancies.
56:
244:
813:
88:
624:
562:
519:
468:
417:
364:
305:
1083:
938:
923:
867:
684:
599:"Porocarcinoma: A systematic review of literature with a single case report"
642:
570:
476:
382:
355:
323:
296:
256:
527:
425:
667:
732:
280:"Oral Capecitabine Achieves Response in Metastatic Eccrine Carcinoma"
72:
744:
76:
952:
705:
129:
There is no research yet as to what causes
Eccrine carcinoma.
197:
James, William D.; Berger, Timothy G.; et al. (2006).
95:. However, metastatic disease carries a poor prognosis.
657:
1114:
1082:
951:
894:
854:
804:
761:
752:
743:
675:
661:
199:
50:
26:
21:
79:, trunk, or extremities. It originates from the
500:Journal of the American Academy of Dermatology
339:"Eccrine carcinoma: a rare cutaneous neoplasm"
717:
603:International Journal of Surgery Case Reports
8:
957:
758:
749:
724:
710:
702:
658:
245:"Cancer, An Overview of Eccrine Carcinoma"
37:
18:
632:
614:
372:
354:
313:
295:
449:The American Journal of Dermatopathology
592:
590:
588:
243:Kaseb, Hatem; Babiker, Hani M. (2020),
189:
87:Most eccrine carcinomas which have not
1102:Folliculosebaceous-apocrine hamartoma
238:
7:
1145:Epidermal nevi, neoplasms, and cysts
284:Case Reports in Oncological Medicine
273:
271:
236:
234:
232:
230:
228:
226:
224:
222:
220:
218:
1097:Folliculosebaceous cystic hamartoma
979:Multiple familial trichoepithelioma
410:10.1111/j.1600-0560.1987.tb00477.x
14:
1059:Tumor of follicular infundibulum
1031:Giant solitary trichoepithelioma
461:10.1097/00000372-200210000-00007
46:Eccrine carcinoma, alveolar type
1026:Proliferating trichilemmal cyst
826:Syringocystadenoma papilliferum
989:Desmoplastic trichoepithelioma
398:Journal of Cutaneous Pathology
1:
1092:Basaloid follicular hamartoma
994:Generalized trichoepithelioma
555:10.1136/jclinpath-2011-200069
543:Journal of Clinical Pathology
173:Microcystic adnexal carcinoma
512:10.1016/0190-9622(91)70133-m
616:10.1016/j.ijscr.2016.10.051
1161:
984:Solitary trichoepithelioma
873:Hidradenoma or Acrospiroma
1054:
960:
771:Papillary eccrine adenoma
251:, StatPearls Publishing,
45:
36:
1124:Neoplasms of the nailbed
929:Sebaceous nevus syndrome
841:Apocrine gland carcinoma
1074:Birt–Hogg–Dubé syndrome
969:Malignant pilomatricoma
1069:Perifollicular fibroma
1021:Trichilemmal carcinoma
356:10.1186/1746-1596-8-15
934:Sebaceous hyperplasia
831:Papillary hidradenoma
796:Malignant acrospiroma
737:associated structures
201:. Saunders Elsevier.
343:Diagnostic Pathology
297:10.1155/2018/7127048
81:eccrine sweat glands
914:Sebaceous carcinoma
909:Muir–Torre syndrome
786:Syringofibroadenoma
93:wide local excision
71:characterized by a
31:Syringoid carcinoma
882:Ceruminous adenoma
877:Hidradenocarcinoma
676:External resources
1132:
1131:
1110:
1109:
1041:Trichofolliculoma
974:Trichoepithelioma
947:
946:
919:Sebaceous adenoma
890:
889:
819:Dermal cylindroma
776:Eccrine carcinoma
699:
698:
65:Eccrine carcinoma
62:
61:
22:Eccrine carcinoma
16:Medical condition
1152:
1064:Fibrofolliculoma
1011:Fibrofolliculoma
958:
759:
750:
726:
719:
712:
703:
659:
647:
646:
636:
618:
594:
583:
582:
538:
532:
531:
495:
489:
488:
444:
438:
437:
393:
387:
386:
376:
358:
334:
328:
327:
317:
299:
275:
266:
265:
264:
263:
240:
213:
212:
194:
91:can be cured by
73:plaque or nodule
41:
19:
1160:
1159:
1155:
1154:
1153:
1151:
1150:
1149:
1135:
1134:
1133:
1128:
1106:
1078:
1050:
943:
904:Nevus sebaceous
896:Sebaceous gland
886:
850:
800:
739:
730:
700:
695:
694:
690:article/1101796
671:
670:
656:
651:
650:
596:
595:
586:
540:
539:
535:
497:
496:
492:
446:
445:
441:
395:
394:
390:
336:
335:
331:
277:
276:
269:
261:
259:
242:
241:
216:
209:
196:
195:
191:
186:
169:
161:
152:
144:
135:
127:
118:
110:
101:
17:
12:
11:
5:
1158:
1156:
1148:
1147:
1137:
1136:
1130:
1129:
1127:
1126:
1120:
1118:
1112:
1111:
1108:
1107:
1105:
1104:
1099:
1094:
1088:
1086:
1080:
1079:
1077:
1076:
1071:
1066:
1061:
1055:
1052:
1051:
1049:
1048:
1043:
1038:
1033:
1028:
1023:
1018:
1013:
1008:
1006:Trichoblastoma
1003:
998:
997:
996:
991:
986:
981:
971:
961:
955:
949:
948:
945:
944:
942:
941:
936:
931:
926:
921:
916:
911:
906:
900:
898:
892:
891:
888:
887:
885:
884:
879:
870:
864:
862:
852:
851:
849:
848:
846:Apocrine nevus
843:
838:
833:
828:
823:
822:
821:
810:
808:
802:
801:
799:
798:
793:
788:
783:
778:
773:
767:
765:
756:
747:
741:
740:
731:
729:
728:
721:
714:
706:
697:
696:
693:
692:
680:
679:
677:
673:
672:
666:
665:
663:
662:Classification
655:
654:External links
652:
649:
648:
584:
549:(9): 788–792.
533:
506:(5): 857–860.
490:
455:(5): 409–413.
439:
388:
329:
267:
214:
207:
188:
187:
185:
182:
181:
180:
175:
168:
165:
160:
157:
151:
148:
143:
140:
134:
131:
126:
123:
117:
114:
109:
106:
100:
97:
69:skin condition
60:
59:
54:
48:
47:
43:
42:
34:
33:
28:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1157:
1146:
1143:
1142:
1140:
1125:
1122:
1121:
1119:
1117:
1113:
1103:
1100:
1098:
1095:
1093:
1090:
1089:
1087:
1085:
1081:
1075:
1072:
1070:
1067:
1065:
1062:
1060:
1057:
1056:
1053:
1047:
1044:
1042:
1039:
1037:
1036:Trichoadenoma
1034:
1032:
1029:
1027:
1024:
1022:
1019:
1017:
1016:Trichilemmoma
1014:
1012:
1009:
1007:
1004:
1002:
1001:Trichodiscoma
999:
995:
992:
990:
987:
985:
982:
980:
977:
976:
975:
972:
970:
966:
965:Pilomatricoma
963:
962:
959:
956:
954:
950:
940:
937:
935:
932:
930:
927:
925:
922:
920:
917:
915:
912:
910:
907:
905:
902:
901:
899:
897:
893:
883:
880:
878:
874:
871:
869:
866:
865:
863:
861:
857:
853:
847:
844:
842:
839:
837:
834:
832:
829:
827:
824:
820:
817:
816:
815:
812:
811:
809:
807:
803:
797:
794:
792:
789:
787:
784:
782:
781:Eccrine nevus
779:
777:
774:
772:
769:
768:
766:
764:
760:
757:
755:
751:
748:
746:
742:
738:
734:
727:
722:
720:
715:
713:
708:
707:
704:
691:
687:
686:
682:
681:
678:
674:
669:
664:
660:
653:
644:
640:
635:
630:
626:
622:
617:
612:
608:
604:
600:
593:
591:
589:
585:
580:
576:
572:
568:
564:
560:
556:
552:
548:
544:
537:
534:
529:
525:
521:
517:
513:
509:
505:
501:
494:
491:
486:
482:
478:
474:
470:
466:
462:
458:
454:
450:
443:
440:
435:
431:
427:
423:
419:
415:
411:
407:
403:
399:
392:
389:
384:
380:
375:
370:
366:
362:
357:
352:
348:
344:
340:
333:
330:
325:
321:
316:
311:
307:
303:
298:
293:
289:
285:
281:
274:
272:
268:
258:
254:
250:
246:
239:
237:
235:
233:
231:
229:
227:
225:
223:
221:
219:
215:
210:
208:0-7216-2921-0
204:
200:
193:
190:
183:
179:
176:
174:
171:
170:
166:
164:
158:
156:
149:
147:
141:
139:
132:
130:
124:
122:
115:
113:
108:Complications
107:
105:
98:
96:
94:
90:
85:
82:
78:
74:
70:
66:
58:
55:
53:
49:
44:
40:
35:
32:
29:
25:
20:
1046:Dilated pore
836:Hidrocystoma
775:
683:
606:
602:
546:
542:
536:
503:
499:
493:
452:
448:
442:
404:(2): 65–86.
401:
397:
391:
346:
342:
332:
287:
283:
260:, retrieved
248:
198:
192:
162:
153:
145:
136:
128:
119:
111:
102:
86:
64:
63:
30:
791:Spiradenoma
754:Sweat gland
178:Skin lesion
57:Dermatology
27:Other names
814:Cylindroma
262:2020-04-22
249:StatPearls
184:References
67:is a rare
1084:Hamartoma
939:Mantleoma
924:Sebaceoma
868:Syringoma
685:eMedicine
625:2210-2612
609:: 13–16.
563:0021-9746
520:0190-9622
469:0193-1091
418:0303-6987
365:1746-1596
349:(1): 15.
306:2090-6706
159:Frequency
150:Prognosis
142:Treatment
133:Diagnosis
52:Specialty
1139:Category
860:apocrine
806:Apocrine
643:27898349
579:46508699
571:21642659
485:20147934
477:12357203
383:23379908
324:29686913
257:31082086
167:See also
99:Symptoms
856:Eccrine
763:Eccrine
634:5128823
528:2050853
434:1897717
426:2439558
374:3570399
315:5852884
290:: 1–5.
75:on the
745:Glands
733:Tumors
641:
631:
623:
577:
569:
561:
526:
518:
483:
475:
467:
432:
424:
416:
381:
371:
363:
322:
312:
304:
255:
205:
125:Causes
89:spread
1116:Nails
575:S2CID
481:S2CID
430:S2CID
116:Types
77:scalp
953:Hair
735:and
639:PMID
621:ISSN
567:PMID
559:ISSN
524:PMID
516:ISSN
473:PMID
465:ISSN
422:PMID
414:ISSN
379:PMID
361:ISSN
320:PMID
302:ISSN
288:2018
253:PMID
203:ISBN
629:PMC
611:doi
551:doi
508:doi
457:doi
406:doi
369:PMC
351:doi
310:PMC
292:doi
1141::
688::
637:.
627:.
619:.
607:30
605:.
601:.
587:^
573:.
565:.
557:.
547:64
545:.
522:.
514:.
504:24
502:.
479:.
471:.
463:.
453:24
451:.
428:.
420:.
412:.
402:14
400:.
377:.
367:.
359:.
345:.
341:.
318:.
308:.
300:.
286:.
282:.
270:^
247:,
217:^
967:/
875:/
858:/
725:e
718:t
711:v
668:D
645:.
613::
581:.
553::
530:.
510::
487:.
459::
436:.
408::
385:.
353::
347:8
326:.
294::
211:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
