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Epiretinal membrane

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membrane (ILM) after PVD also may provide retinal astrocytes access to the vitreous cavity, where they may subsequently proliferate. Many ERMs also have ILM fragments that may be peeled separately. Finally, vitreous hemorrhage, inflammation, or both associated with a PVD also may stimulate ERM formation.
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The incidence of associated PVD ranges from 75 to 93%, and PVD is present in virtually all eyes with retinal breaks or retinal detachments and subsequent ERM formation. PVD can lead to retinal breaks that may liberate RPE cells that initiate membrane formation. Small breaks in the internal limiting
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The source of the cells in epiretinal membranes (ERM) has been found to comprise glial cells, retinal pigment epithelial (RPE) cells, macrophages, fibrocytes, and collagen cells. These cells are found in varying proportions. Those from retinal breaks, previous retinal detachments, or cryopexy are
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This ocular pathology was first described by Iwanoff in 1865, and it has been shown to occur in about 7% of the population. It can occur more frequently in the older population with postmortem studies showing it in 2% of those aged 50 years and 20% in those aged 75 years.
701: 312:(OCT) of the macula. Features include a thickening of the nerve fiber layer, a serrated appearance to the surface of the retina just beneath a thickened layer of glial tissue at the retinal-vitreous interface. 247:
In the young (under 50 years of age), these cells occasionally pull free and disintegrate on their own; but in the majority of those affected (over 60 years of age) the condition is permanent. The underlying
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There is no good evidence for any preventive actions, since it appears this is a natural response to aging changes in the vitreous. It has been estimated that
1869: 1795: 293:. The presence of retinal pigment cells invariably indicates proliferative retinopathy and is only seen in association with a retinal detachment or tear. 280:, as it might be viewed by a person with very severe macular pucker. Most cases of epiretinal membrane are milder and show much smoother curved lines. 236:
if the image from one eye is too different from the image of the other eye. The distortions can make objects look different in size (usually larger =
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Dev S, Mieler WF, Pulido JS, Mittra RA (1999). "Visual outcomes after pars plana vitrectomy for epiretinal membranes associated with pars planitis".
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For severe epiretinal membrane, surgery may be recommended; however, there are the usual hazards of surgery, infections, and a possibility of
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Benson WE, Brown GC, Tasman W, McNamara JA (1988). "Complications of vitrectomy for non-clearing vitreous hemorrhage in diabetic patients".
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are the fundamental cell type in idiopathic ERMs. These cells are frequently found in small and dispersed numbers in eyes containing a
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that cannot be fully corrected optically with glasses. Partial correction often improves the binocular vision considerably though.
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Gibran SK; B Flemming; T Stappler; I Pearce; C Groenewald; H Heimann; P Hiscott; D Wong (2008). "Peel and peel again".
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Suami M, Mizota A, Hotta Y, Tanaka M (2007). "Pattern VEPs before and after idiopathic epiretinal membrane removal".
75: 1807: 1603: 1577: 1535: 1530: 1395: 1268: 1256: 1212: 1874: 1273: 35: 1986: 1780: 1627: 1472: 1219: 431:, a film monologue describing his experiences dealing with a macular pucker and his decision to undergo surgery. 57: 1525: 1496: 1120: 1085: 716: 374:. Surgery is not usually recommended unless the distortions are severe enough to interfere with daily living. 1996: 1750: 1550: 1070: 1063: 2265: 2235: 2170: 2165: 1892: 1170: 1035: 795: 136: 285:
composed mainly of dispersed RPE cells, while cells of glial origin predominate in idiopathic pathology.
2208: 1884: 1981: 1567: 1562: 1520: 1335: 1251: 459: 261: 173: 2286: 2160: 1960: 1843: 1835: 1623: 1572: 1427: 1207: 987: 705: 260:, are usually not damaged unless the membrane becomes quite thick and hard; so usually there is no 249: 240:), especially in the central portion of the visual field, creating a localized or field-dependent 1897: 1647: 1555: 1479: 1432: 1244: 1180: 1165: 1025: 974: 603: 514: 378: 286: 82: 217:, tighten to create tension on the retina which may bulge and pucker, or even cause swelling or 198:. Sometimes, as a result of immune system response to protect the retina, cells converge in the 2240: 2137: 1902: 1762: 1545: 1202: 1108: 727: 667: 632: 595: 566: 545: 506: 162: 2028: 2018: 1864: 1839: 1772: 1738: 1657: 1288: 1278: 1175: 1030: 917: 907: 657: 624: 587: 496: 488: 210: 2095: 2059: 2023: 1642: 1467: 1454: 1388: 1345: 1263: 1075: 1007: 927: 912: 351: 440:, Ruth had epiretinal membrane complicated by macular edema in her left vitreous cavity. 2325: 2177: 2122: 1965: 1733: 1662: 1444: 1414: 1360: 1314: 1185: 1058: 992: 982: 710: 662: 645: 191: 145: 628: 370:
lines. Usually the vitreous is replaced at the same time with clear (BSS) fluid, in a
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However, since epiretinal membrane appears to be a protective response to PVD, where
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PVD can create minor damage to the retina, stimulating exudate, inflammation, and
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response. These cells can form a transparent layer gradually and, like all
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created by cataracts may sometimes be confused with epiretinal membrane.
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Usually there are flashing-light experiences and the emergence of
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Epiretinal membrane is typically diagnosed by appearance with
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Usually it occurs in one eye first, and may cause binocular
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Macular pucker, epimacular membrane, preretinal membrane,
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is a disease of the eye in response to changes in the
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Resource Guide from the National Eye Institute (NEI).
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Surgeons can remove or peel the membrane through the
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Both sexes appear to be affected equally frequently.
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January 10, 2004), an 803: 8: 1870:Chronic progressive external ophthalmoplegia 202:area as the vitreous ages and pulls away in 1198:Thygeson's superficial punctate keratopathy 2304: 2068: 1857: 1848: 1726: 1713: 1700: 1307: 1125: 1116: 1103: 854: 845: 832: 810: 796: 788: 684: 172: 144: 123: 661: 500: 109:Learn how and when to remove this message 471: 343:may reduce the inflammation response. 354:before the epiretinal membrane forms. 350:in the eye that herald changes in the 7: 1678:Familial exudative vitreoretinopathy 47:adding citations to reliable sources 1801:non-arteritic anterior (NAION) 1638:Leber's hereditary optic neuropathy 1673:Persistent tunica vasculosa lentis 14: 1401:Polypoidal choroidal vasculopathy 1506:Central retinal artery occlusion 481:British Journal of Ophthalmology 366:and improve vision by 2 or more 23: 2351:Disorders of choroid and retina 1511:Branch retinal artery occlusion 1240:Terrien's marginal degeneration 339:is formed, it is possible that 34:needs additional citations for 1541:Bietti's crystalline dystrophy 1501:Central retinal vein occlusion 1230:Pellucid marginal degeneration 1: 1594:Vitelliform macular dystrophy 1485:Posterior vitreous detachment 1351:Persistent pupillary membrane 629:10.1016/S0161-6420(99)90247-6 322:Posterior vitreous detachment 204:posterior vitreous detachment 2081:Leber's congenital amaurosis 1992:Internuclear ophthalmoplegia 1683:Vogt-Koyanagi-Harada disease 1668:Persistent fetal vasculature 1599:Leber's congenital amaurosis 310:optical coherence tomography 880:Meibomian gland dysfunction 2367: 1604:Birdshot chorioretinopathy 1578:Central serous retinopathy 1396:Focal choroidal excavation 1269:Corneal neovascularization 1086:Subconjunctival hemorrhage 2316: 2303: 2071: 1987:Convergence insufficiency 1860: 1729: 1712: 1699: 1628:Primary juvenile glaucoma 1473:Cytomegalovirus retinitis 1115: 1102: 888: 844: 831: 822:Diseases of the human eye 592:10.1007/s10633-006-9039-4 152: 143: 1497:Ocular ischemic syndrome 538:Binocul Vis Strabismus Q 1997:One and a half syndrome 1751:Foster Kennedy syndrome 650:Trans Am Ophthalmol Soc 493:10.1136/bjo.2007.129965 157:image. 89-year-old man. 2236:Argyll Robertson pupil 1036:Periorbital cellulitis 281: 137:cellophane maculopathy 2209:Scintillating scotoma 1875:Kearns–Sayre syndrome 1818:Toxic and nutritional 1791:posterior (PION) 1274:Kayser–Fleischer ring 530:Additional references 275: 153:Epiretinal membrane, 58:"Epiretinal membrane" 1982:Conjugate gaze palsy 1853:Paralytic strabismus 1786:anterior (AION) 1568:Retinitis pigmentosa 1563:Macular degeneration 1336:Intermediate uveitis 1252:Keratoconjunctivitis 460:macular degeneration 262:macular degeneration 43:improve this article 2287:Childhood blindness 2266:Parinaud's syndrome 1836:Extraocular muscles 1624:Ocular hypertension 1588:Epiretinal membrane 1573:Retinal haemorrhage 1428:Congenital cataract 644:Johnson MW (2005). 250:photoreceptor cells 184:Epiretinal membrane 127:Epiretinal membrane 1813:Leber's hereditary 1480:Retinal detachment 1433:Childhood cataract 1245:Post-LASIK ectasia 1026:Orbital cellulitis 975:Lacrimal apparatus 754:External resources 379:retinal detachment 282: 2338: 2337: 2334: 2333: 2299: 2298: 2295: 2294: 2241:Marcus Gunn pupil 2217: 2216: 2138:Visual impairment 2005: 2004: 1911: 1910: 1898:Fourth-nerve (IV) 1826: 1825: 1763:Optic disc drusen 1695: 1694: 1691: 1690: 1409: 1408: 1297: 1296: 1203:Corneal dystrophy 1098: 1097: 1094: 1093: 969: 968: 777: 776: 434:In the 2011 film 181: 180: 121:Medical condition 119: 118: 111: 93: 2358: 2305: 2069: 2060:Vision disorders 2019:Refractive error 1961:Brown's syndrome 1917:Other strabismus 1903:Sixth-nerve (VI) 1893:Oculomotor (III) 1865:Ophthalmoparesis 1858: 1849: 1840:Binocular vision 1773:Optic neuropathy 1739:optic papillitis 1727: 1714: 1701: 1590:(Macular pucker) 1308: 1289:Band keratopathy 1126: 1117: 1104: 1031:Orbital lymphoma 918:Blepharophimosis 908:Blepharochalasis 855: 846: 833: 812: 805: 798: 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1088: 1083: 1078: 1073: 1068: 1067: 1066: 1059:Conjunctivitis 1056: 1050: 1048: 1042: 1041: 1039: 1038: 1033: 1028: 1023: 1018: 1012: 1010: 1004: 1003: 1001: 1000: 995: 993:Dacryocystitis 990: 985: 983:Dacryoadenitis 979: 977: 971: 970: 967: 966: 964: 963: 958: 953: 948: 942: 940: 934: 933: 931: 930: 925: 920: 915: 910: 905: 900: 895: 889: 886: 885: 883: 882: 877: 872: 867: 861: 859: 852: 842: 841: 836: 829: 828: 825: 824: 818: 817: 815: 814: 807: 800: 792: 786: 785: 782:Macular Pucker 775: 774: 771: 770: 758: 757: 755: 751: 750: 747: 746: 735: 724: 713: 697: 692: 691: 689: 688:Classification 681: 680:External links 678: 677: 676: 641: 623:(6): 1086–90. 612: 580:Doc Ophthalmol 575: 554: 531: 528: 525: 524: 470: 469: 467: 464: 463: 462: 457: 452: 445: 442: 428:Gray's Anatomy 403: 400: 394: 391: 359: 356: 317: 314: 305: 302: 269: 266: 192:vitreous humor 188:macular pucker 179: 178: 165: 159: 158: 150: 149: 141: 140: 133: 129: 128: 120: 117: 116: 31: 29: 22: 15: 13: 10: 9: 6: 4: 3: 2: 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1069: 1065: 1062: 1061: 1060: 1057: 1055: 1052: 1051: 1049: 1047: 1043: 1037: 1034: 1032: 1029: 1027: 1024: 1022: 1019: 1017: 1014: 1013: 1011: 1009: 1005: 999: 998:Xerophthalmia 996: 994: 991: 989: 986: 984: 981: 980: 978: 976: 972: 962: 959: 957: 954: 952: 949: 947: 944: 943: 941: 939: 935: 929: 926: 924: 921: 919: 916: 914: 911: 909: 906: 904: 903:Lagophthalmos 901: 899: 896: 894: 891: 890: 887: 881: 878: 876: 873: 871: 868: 866: 863: 862: 860: 856: 853: 851: 847: 843: 839: 834: 830: 823: 820: 819: 813: 808: 806: 801: 799: 794: 793: 790: 783: 780: 779: 769: 765: 764: 760: 759: 756: 752: 745: 741: 740: 736: 734: 730: 729: 725: 723: 719: 718: 714: 712: 708: 707: 703: 699: 698: 695: 690: 686: 679: 673: 669: 664: 659: 655: 651: 647: 642: 638: 634: 630: 626: 622: 618: 617:Ophthalmology 613: 609: 605: 601: 597: 593: 589: 585: 581: 576: 572: 568: 565:(12): 862–4. 564: 560: 555: 551: 547: 544:(2): 96–101. 543: 539: 534: 533: 529: 520: 516: 512: 508: 503: 498: 494: 490: 487:(3): 373–77. 486: 482: 475: 472: 465: 461: 458: 456: 453: 451: 448: 447: 443: 441: 439: 438: 432: 430: 429: 424: 420: 416: 413: 409: 408:Spalding Gray 401: 399: 392: 390: 388: 384: 380: 375: 373: 369: 365: 357: 355: 353: 349: 344: 342: 338: 334: 330: 325: 323: 315: 313: 311: 303: 301: 298: 294: 292: 288: 279: 274: 267: 265: 263: 259: 255: 251: 245: 243: 239: 235: 234:double vision 231: 226: 224: 220: 219:macular edema 216: 212: 207: 205: 201: 197: 193: 189: 185: 175: 169: 168:Ophthalmology 166: 164: 160: 156: 151: 147: 142: 138: 134: 130: 125: 113: 110: 102: 91: 88: 84: 81: 77: 74: 70: 67: 63: 60: â€“  59: 55: 54:Find sources: 48: 44: 38: 37: 32:This article 30: 26: 21: 20: 2136: / 2132: / 2111:Monochromacy 2043: / 1939:Heterophoria 1927: / 1626: / 1622: / 1587: 1526:hypertensive 1499: / 1320:Ciliary body 1235:Keratoglobus 1143:Episcleritis 1021:Enophthalmos 1016:Exophthalmos 961:Trichomegaly 956:Distichiasis 858:Inflammation 761: 737: 726: 715: 700: 653: 649: 620: 616: 586:(2): 67–73. 583: 579: 562: 558: 541: 537: 484: 480: 474: 435: 433: 426: 419:screenwriter 405: 396: 393:Epidemiology 376: 361: 345: 329:inflammation 326: 319: 307: 299: 295: 283: 246: 227: 208: 187: 183: 182: 105: 96: 86: 79: 72: 65: 53: 41:Please help 36:verification 33: 2261:Cycloplegia 2204:Photophobia 2199:Hemeralopia 2156:Hemianopsia 2134:Vision loss 2045:Aniseikonia 2036:Astigmatism 1956:Cyclotropia 1934:Hypertropia 1746:Papilledema 1718:Optic nerve 1551:Sickle cell 1531:Purtscher's 1516:Retinopathy 1384:Choroiditis 1225:Keratoconus 1046:Conjunctiva 923:Xanthelasma 875:Blepharitis 502:10722/90372 450:Eye surgery 425:, released 337:scar tissue 335:fluid, and 287:Laminocytes 278:Amsler grid 242:aniseikonia 223:Amsler grid 215:scar tissue 132:Other names 16:Eye disease 2310:Infections 2231:Anisocoria 2194:Asthenopia 2187:subjective 2171:homonymous 2166:bitemporal 2118:Nyctalopia 2106:Dichromacy 2050:Presbyopia 2011:Refraction 1832:Strabismus 1722:Optic disc 1081:Pinguecula 946:Trichiasis 728:DiseasesDB 656:: 537–67. 466:References 423:playwright 372:vitrectomy 316:Prevention 258:cone cells 69:newspapers 2282:Nystagmus 2256:Mydriasis 2130:Blindness 2076:Amblyopia 2064:Blindness 2024:Hyperopia 1949:Exophoria 1944:Esophoria 1929:Exotropia 1925:Esotropia 1463:Retinitis 1161:Keratitis 1138:Scleritis 1071:Pterygium 951:Madarosis 898:Ectropion 893:Entropion 870:Chalazion 763:eMedicine 744:133853005 739:SNOMED CT 406:In 1996, 383:cataracts 358:Treatment 333:exudative 304:Diagnosis 254:rod cells 238:macropsia 211:leucocyte 163:Specialty 99:June 2019 2345:Category 2321:Trachoma 2086:Diplopia 1781:Ischemic 1706:Pathways 1620:Glaucoma 1521:diabetic 1423:Cataract 1361:Synechia 1213:Meesmann 1181:Exposure 1166:herpetic 1064:allergic 1054:Chemosis 988:Epiphora 672:17057817 637:10366075 608:22039065 600:17216518 550:17688418 519:42887974 511:18055573 444:See also 412:American 387:diplopia 352:vitreous 348:floaters 230:diplopia 206:(PVD). 196:diabetes 2161:binasal 2148:Anopsia 2091:Scotoma 1885:palsies 1648:Red eye 1633:Floater 1440:Aphakia 1371:Choroid 1341:Hyphema 1331:Uveitis 938:Eyelash 768:oph/396 722:D019773 663:1447588 571:3231410 402:Culture 368:Snellen 200:macular 83:scholar 2251:Miosis 2029:Myopia 1808:Kjer's 1556:photic 1455:Retina 1208:Fuchs' 1176:fungal 1153:Cornea 1130:Sclera 913:Ptosis 850:Eyelid 838:Adnexa 711:362.56 670:  660:  635:  606:  598:  569:  548:  517:  509:  455:macula 421:, and 364:sclera 341:NSAIDs 170:  85:  78:  71:  64:  56:  2275:Other 2223:Pupil 1613:Other 1257:sicca 1109:Globe 1008:Orbit 733:31161 604:S2CID 515:S2CID 415:actor 268:Cause 90:JSTOR 76:books 1415:Lens 1315:Iris 865:Stye 717:MeSH 706:9-CM 668:PMID 633:PMID 596:PMID 567:PMID 546:PMID 507:PMID 437:Paul 256:and 62:news 702:ICD 658:PMC 654:103 625:doi 621:106 588:doi 584:114 497:hdl 489:doi 291:PVD 276:An 232:or 186:or 155:OCT 45:by 2347:: 766:: 742:: 731:: 720:: 709:: 666:. 652:. 648:. 631:. 619:. 602:. 594:. 582:. 563:19 561:. 542:22 540:. 513:. 505:. 495:. 485:92 483:. 417:, 331:, 264:. 252:, 811:e 804:t 797:v 704:- 694:D 674:. 639:. 627:: 610:. 590:: 573:. 552:. 521:. 499:: 491:: 112:) 106:( 101:) 97:( 87:· 80:· 73:· 66:· 39:.

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cellophane maculopathy

OCT
Specialty
Ophthalmology
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vitreous humor
diabetes
macular
posterior vitreous detachment
leucocyte
scar tissue
macular edema
Amsler grid
diplopia
double vision
macropsia
aniseikonia
photoreceptor cells

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