1175:
317:, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with 2-oxoglutarate as one donor, and incorporation of one atom o oxygen into each donor. The
374:
G, Martens S; Matern, U; Junghanns, KT; Heskamp, ML; Britsch, L; Forkmann, G; Martens, S (2001). "Purification and antigenicity of flavone synthase I from irradiated parsley cells".
250:
163:
182:
1232:
652:
545:
720:
459:
1256:
620:
894:
593:
175:
632:
578:
142:
1225:
118:
1050:
437:
1261:
861:
710:
1165:
452:
1035:
136:
1218:
1151:
1138:
1125:
1112:
1099:
1086:
1073:
856:
817:
807:
793:
789:
779:
767:
747:
730:
698:
662:
562:
489:
330:
1045:
999:
942:
480:
345:
265:
208:
123:
29:
702:
947:
493:
187:
1266:
841:
757:
506:
326:
111:
235:
968:
887:
637:
610:
445:
1040:
46:
752:
715:
476:
139:
63:
1251:
1004:
738:
284:
41:
937:
501:
647:
535:
426:
391:
362:
223:
130:
99:
983:
978:
952:
880:
416:
383:
354:
343:
Martens S, Forkmann G, Matern U, Lukacin R (2001). "Cloning of parsley flavone synthase I".
75:
1030:
1014:
927:
625:
318:
34:
1202:
1179:
1068:
1009:
851:
831:
826:
468:
314:
296:
273:
158:
421:
404:
358:
1245:
973:
932:
922:
670:
666:
405:"Divergent evolution of flavonoid 2-oxoglutarate-dependent dioxygenases in parsley"
1146:
1081:
917:
1174:
802:
200:
1120:
1094:
771:
734:
678:
472:
292:
269:
219:
430:
395:
387:
366:
403:
Martens S, Forkmann G, Britsch L, Wellmann F, Matern U, Lukacin R (2003).
211:
87:
550:
1195:
846:
288:
106:
1198:
1133:
903:
688:
683:
642:
277:
215:
170:
82:
70:
58:
1107:
835:
570:
528:
521:
516:
511:
303:
615:
603:
598:
588:
583:
566:
540:
94:
876:
441:
323:
flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating)
872:
239:
1206:
1163:
238:
1059:
1023:
992:
961:
910:
816:
788:
766:
729:
697:
661:
561:
488:
181:
169:
157:
152:
129:
117:
105:
93:
81:
69:
57:
52:
40:
28:
23:
18:
244:
1226:
888:
453:
8:
1233:
1219:
895:
881:
873:
460:
446:
438:
149:
420:
237:
1170:
15:
313:This enzyme belongs to the family of
7:
1191:
1189:
653:24-hydroxycholesterol 7α-hydroxylase
245:{\displaystyle \rightleftharpoons }
14:
1173:
229:a flavanone + 2-oxoglutarate + O
633:Cholesterol 7 alpha-hydroxylase
579:Flavin-containing monooxygenase
325:. This enzyme participates in
1:
422:10.1016/S0014-5793(03)00479-4
359:10.1016/S0031-9422(01)00191-1
1257:Enzymes of unknown structure
1205:. You can help Knowledge by
862:Deoxyhypusine monooxygenase
1283:
1188:
252:a flavone + succinate + CO
1051:Michaelis–Menten kinetics
857:Ecdysone 20-monooxygenase
808:Stearoyl-CoA desaturase-1
780:Dopamine beta-hydroxylase
748:Phenylalanine hydroxylase
331:isoflavonoid biosynthesis
148:
943:Diffusion-limited enzyme
321:of this enzyme class is
1201:-related article is a
842:Squalene monooxygenase
758:Tryptophan hydroxylase
507:HIF prolyl-hydroxylase
388:10.1006/abbi.2001.2491
376:Arch. Biochem. Biophys
327:flavonoid biosynthesis
246:
1036:Eadie–Hofstee diagram
969:Allosteric regulation
638:Methane monooxygenase
611:Nitric oxide synthase
247:
1046:Lineweaver–Burk plot
753:Tyrosine hydroxylase
477:steroid hydroxylases
236:
1262:Flavones metabolism
703:iron–sulfur protein
268:of this enzyme are
1005:Enzyme superfamily
938:Enzyme promiscuity
502:Prolyl hydroxylase
242:
1214:
1213:
1161:
1160:
870:
869:
536:Lysyl hydroxylase
224:chemical reaction
197:
196:
193:
192:
112:metabolic pathway
1274:
1235:
1228:
1221:
1190:
1178:
1177:
1169:
1041:Hanes–Woolf plot
984:Enzyme activator
979:Enzyme inhibitor
953:Enzyme catalysis
897:
890:
883:
874:
462:
455:
448:
439:
434:
424:
399:
370:
283:, whereas its 4
251:
249:
248:
243:
205:flavone synthase
150:
19:Flavone synthase
16:
1282:
1281:
1277:
1276:
1275:
1273:
1272:
1271:
1242:
1241:
1240:
1239:
1186:
1184:
1172:
1164:
1162:
1157:
1069:Oxidoreductases
1055:
1031:Enzyme kinetics
1019:
1015:List of enzymes
988:
957:
928:Catalytic triad
906:
901:
871:
866:
820:- miscellaneous
812:
784:
762:
725:
693:
657:
648:14α-demethylase
557:
484:
469:Oxidoreductases
466:
402:
373:
342:
339:
319:systematic name
315:oxidoreductases
307:
300:
281:
259:
255:
234:
233:
232:
12:
11:
5:
1280:
1278:
1270:
1269:
1264:
1259:
1254:
1244:
1243:
1238:
1237:
1230:
1223:
1215:
1212:
1211:
1183:
1182:
1159:
1158:
1156:
1155:
1142:
1129:
1116:
1103:
1090:
1077:
1063:
1061:
1057:
1056:
1054:
1053:
1048:
1043:
1038:
1033:
1027:
1025:
1021:
1020:
1018:
1017:
1012:
1007:
1002:
996:
994:
993:Classification
990:
989:
987:
986:
981:
976:
971:
965:
963:
959:
958:
956:
955:
950:
945:
940:
935:
930:
925:
920:
914:
912:
908:
907:
902:
900:
899:
892:
885:
877:
868:
867:
865:
864:
859:
854:
849:
844:
839:
832:Heme oxygenase
829:
827:Cyclooxygenase
823:
821:
814:
813:
811:
810:
805:
799:
797:
786:
785:
783:
782:
776:
774:
764:
763:
761:
760:
755:
750:
744:
742:
727:
726:
724:
723:
718:
713:
707:
705:
695:
694:
692:
691:
686:
681:
675:
673:
659:
658:
656:
655:
650:
645:
640:
635:
630:
629:
628:
623:
618:
608:
607:
606:
601:
596:
591:
586:
575:
573:
559:
558:
556:
555:
554:
553:
548:
538:
533:
532:
531:
526:
525:
524:
519:
514:
498:
496:
494:2-oxoglutarate
486:
485:
467:
465:
464:
457:
450:
442:
436:
435:
400:
371:
346:Phytochemistry
338:
335:
305:
298:
279:
274:2-oxoglutarate
262:
261:
257:
253:
241:
230:
195:
194:
191:
190:
185:
179:
178:
173:
167:
166:
161:
155:
154:
146:
145:
134:
127:
126:
121:
115:
114:
109:
103:
102:
97:
91:
90:
85:
79:
78:
73:
67:
66:
61:
55:
54:
50:
49:
44:
38:
37:
32:
26:
25:
21:
20:
13:
10:
9:
6:
4:
3:
2:
1279:
1268:
1267:EC 1.14 stubs
1265:
1263:
1260:
1258:
1255:
1253:
1250:
1249:
1247:
1236:
1231:
1229:
1224:
1222:
1217:
1216:
1210:
1208:
1204:
1200:
1197:
1192:
1187:
1181:
1176:
1171:
1167:
1153:
1149:
1148:
1143:
1140:
1136:
1135:
1130:
1127:
1123:
1122:
1117:
1114:
1110:
1109:
1104:
1101:
1097:
1096:
1091:
1088:
1084:
1083:
1078:
1075:
1071:
1070:
1065:
1064:
1062:
1058:
1052:
1049:
1047:
1044:
1042:
1039:
1037:
1034:
1032:
1029:
1028:
1026:
1022:
1016:
1013:
1011:
1010:Enzyme family
1008:
1006:
1003:
1001:
998:
997:
995:
991:
985:
982:
980:
977:
975:
974:Cooperativity
972:
970:
967:
966:
964:
960:
954:
951:
949:
946:
944:
941:
939:
936:
934:
933:Oxyanion hole
931:
929:
926:
924:
921:
919:
916:
915:
913:
909:
905:
898:
893:
891:
886:
884:
879:
878:
875:
863:
860:
858:
855:
853:
850:
848:
845:
843:
840:
837:
833:
830:
828:
825:
824:
822:
819:
815:
809:
806:
804:
801:
800:
798:
795:
791:
787:
781:
778:
777:
775:
773:
769:
765:
759:
756:
754:
751:
749:
746:
745:
743:
740:
739:BH4 dependent
736:
732:
728:
722:
719:
717:
714:
712:
709:
708:
706:
704:
700:
696:
690:
687:
685:
682:
680:
677:
676:
674:
672:
668:
664:
660:
654:
651:
649:
646:
644:
641:
639:
636:
634:
631:
627:
624:
622:
619:
617:
614:
613:
612:
609:
605:
602:
600:
597:
595:
592:
590:
587:
585:
582:
581:
580:
577:
576:
574:
572:
568:
564:
560:
552:
549:
547:
544:
543:
542:
539:
537:
534:
530:
527:
523:
520:
518:
515:
513:
510:
509:
508:
505:
504:
503:
500:
499:
497:
495:
491:
487:
482:
478:
474:
470:
463:
458:
456:
451:
449:
444:
443:
440:
432:
428:
423:
418:
415:(1–3): 93–8.
414:
410:
406:
401:
397:
393:
389:
385:
382:(1): 177–83.
381:
377:
372:
368:
364:
360:
356:
352:
348:
347:
341:
340:
336:
334:
332:
328:
324:
320:
316:
311:
309:
301:
294:
290:
286:
282:
275:
271:
267:
228:
227:
226:
225:
221:
217:
213:
210:
206:
202:
189:
186:
184:
180:
177:
174:
172:
168:
165:
162:
160:
156:
151:
147:
144:
141:
138:
135:
132:
128:
125:
122:
120:
116:
113:
110:
108:
104:
101:
98:
96:
92:
89:
88:NiceZyme view
86:
84:
80:
77:
74:
72:
68:
65:
62:
60:
56:
51:
48:
45:
43:
39:
36:
33:
31:
27:
22:
17:
1207:expanding it
1193:
1185:
1147:Translocases
1144:
1131:
1118:
1105:
1092:
1082:Transferases
1079:
1066:
923:Binding site
671:flavoprotein
475:, including
473:dioxygenases
412:
408:
379:
375:
350:
344:
322:
312:
263:
204:
198:
76:BRENDA entry
47:138263-98-6
918:Active site
353:(1): 43–6.
64:IntEnz view
24:Identifiers
1252:EC 1.14.11
1246:Categories
1121:Isomerases
1095:Hydrolases
962:Regulation
803:Tyrosinase
770:: reduced
733:: reduced
701:: reduced
665:: reduced
337:References
266:substrates
212:1.14.11.22
201:enzymology
133:structures
100:KEGG entry
35:1.14.11.22
1000:EC number
772:ascorbate
735:pteridine
409:FEBS Lett
293:succinate
270:flavanone
240:⇌
220:catalyzes
53:Databases
1024:Kinetics
948:Cofactor
911:Activity
431:12782296
396:11516175
367:11524111
285:products
214:) is an
188:proteins
176:articles
164:articles
137:RCSB PDB
1196:EC 1.14
1180:Biology
1134:Ligases
904:Enzymes
818:1.14.99
796:: other
790:1.14.18
768:1.14.17
731:1.14.16
699:1.14.15
663:1.14.14
563:1.14.13
490:1.14.11
289:flavone
124:profile
107:MetaCyc
42:CAS no.
1199:enzyme
1166:Portal
1108:Lyases
667:flavin
546:ALKBH1
429:
394:
365:
302:, and
276:, and
264:The 3
216:enzyme
171:PubMed
153:Search
143:PDBsum
83:ExPASy
71:BRENDA
59:IntEnz
30:EC no.
1194:This
1060:Types
836:HMOX1
571:NADPH
529:P4HTM
522:EGLN3
517:EGLN2
512:EGLN1
483:1.14)
218:that
119:PRIAM
1203:stub
1152:list
1145:EC7
1139:list
1132:EC6
1126:list
1119:EC5
1113:list
1106:EC4
1100:list
1093:EC3
1087:list
1080:EC2
1074:list
1067:EC1
852:21A2
847:17A1
721:11A1
716:11B2
711:11B1
679:19A1
626:NOS3
621:NOS2
616:NOS1
604:FMO5
599:FMO4
594:FMO3
589:FMO2
584:FMO1
567:NADH
541:AlkB
427:PMID
392:PMID
363:PMID
329:and
287:are
222:the
203:, a
183:NCBI
140:PDBe
95:KEGG
689:2E1
684:2D6
669:or
643:3A4
569:or
551:FTO
417:doi
413:544
384:doi
380:393
355:doi
256:+ H
199:In
159:PMC
131:PDB
1248::
794:19
565::
492::
481:EC
471::
425:.
411:.
407:.
390:.
378:.
361:.
351:58
349:.
333:.
310:.
297:CO
295:,
291:,
272:,
209:EC
1234:e
1227:t
1220:v
1209:.
1168::
1154:)
1150:(
1141:)
1137:(
1128:)
1124:(
1115:)
1111:(
1102:)
1098:(
1089:)
1085:(
1076:)
1072:(
896:e
889:t
882:v
838:)
834:(
792:-
741:)
737:(
479:(
461:e
454:t
447:v
433:.
419::
398:.
386::
369:.
357::
308:O
306:2
304:H
299:2
280:2
278:O
260:O
258:2
254:2
231:2
207:(
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